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gem-squad_v2-train-28700
5a0f8530decec900184755c8
Canadian_football
During the last three minutes of a half, the penalty for failure to place the ball in play within the 20-second play clock, known as "time count" (this foul is known as "delay of game" in American football), is dramatically different from during the first 27 minutes. Instead of the penalty being 5 yards with the down r...
How many yards does the loss of down lose on third down?
How many yards does the loss of down lose on third down?
[ "How many yards does the loss of down lose on third down?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28701
5a0f8530decec900184755c9
Canadian_football
During the last three minutes of a half, the penalty for failure to place the ball in play within the 20-second play clock, known as "time count" (this foul is known as "delay of game" in American football), is dramatically different from during the first 27 minutes. Instead of the penalty being 5 yards with the down r...
On what down can the 20 second play clock give possession to the defense?
On what down can the 20 second play clock give possession to the defense?
[ "On what down can the 20 second play clock give possession to the defense?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28702
572e9091cb0c0d14000f12aa
Canadian_football
The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter cannot end ...
What happens to a quarter whose time expires while the ball is still live in play?
What happens to a quarter whose time expires while the ball is still live in play?
[ "What happens to a quarter whose time expires while the ball is still live in play?" ]
{ "text": [ "extended" ], "answer_start": [ 161 ] }
gem-squad_v2-train-28703
572e9091cb0c0d14000f12ab
Canadian_football
The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter cannot end ...
What causes a quarter to be extended one additional play even if time has run out?
What causes a quarter to be extended one additional play even if time has run out?
[ "What causes a quarter to be extended one additional play even if time has run out?" ]
{ "text": [ "penalty" ], "answer_start": [ 328 ] }
gem-squad_v2-train-28704
572e9091cb0c0d14000f12ac
Canadian_football
The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter cannot end ...
How long is a quarter in minutes?
How long is a quarter in minutes?
[ "How long is a quarter in minutes?" ]
{ "text": [ "15" ], "answer_start": [ 91 ] }
gem-squad_v2-train-28705
572e9091cb0c0d14000f12ad
Canadian_football
The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter cannot end ...
Which plays do not cause time to run off the clock during the final minutes of a half?
Which plays do not cause time to run off the clock during the final minutes of a half?
[ "Which plays do not cause time to run off the clock during the final minutes of a half?" ]
{ "text": [ "convert attempts" ], "answer_start": [ 30 ] }
gem-squad_v2-train-28706
5a0f91a2decec900184755cf
Canadian_football
The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter cannot end ...
When does the clock not run when a penalty is pending?
When does the clock not run when a penalty is pending?
[ "When does the clock not run when a penalty is pending?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28707
5a0f91a2decec900184755d0
Canadian_football
The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter cannot end ...
If a quarter's time expires while the ball is pending how long is the quarter extended?
If a quarter's time expires while the ball is pending how long is the quarter extended?
[ "If a quarter's time expires while the ball is pending how long is the quarter extended?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28708
5a0f91a2decec900184755d1
Canadian_football
The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter cannot end ...
When can't a scrimmage end?
When can't a scrimmage end?
[ "When can't a scrimmage end?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28709
5a0f91a2decec900184755d2
Canadian_football
The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter cannot end ...
What does the losing team have the option to do?
What does the losing team have the option to do?
[ "What does the losing team have the option to do?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28710
5a0f91a2decec900184755d3
Canadian_football
The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter cannot end ...
What is the name of the plays where the clock doesn't run near the end of a half?
What is the name of the plays where the clock doesn't run near the end of a half?
[ "What is the name of the plays where the clock doesn't run near the end of a half?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28711
572e92c5c246551400ce4368
Canadian_football
In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs until it sc...
What determines which team gets possession first when extending a game to break a tie?
What determines which team gets possession first when extending a game to break a tie?
[ "What determines which team gets possession first when extending a game to break a tie?" ]
{ "text": [ "coin toss" ], "answer_start": [ 134 ] }
gem-squad_v2-train-28712
572e92c5c246551400ce4369
Canadian_football
In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs until it sc...
At which yard line on their opponent's side does a team take possession of the ball according to the CFL's tie-breaking rules?
At which yard line on their opponent's side does a team take possession of the ball according to the CFL's tie-breaking rules?
[ "At which yard line on their opponent's side does a team take possession of the ball according to the CFL's tie-breaking rules?" ]
{ "text": [ "35" ], "answer_start": [ 257 ] }
gem-squad_v2-train-28713
572e92c5c246551400ce436a
Canadian_football
In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs until it sc...
In which year did the CFL begin requiring teams to attempt 2-point conversions after scoring in a tie-breaking situation?
In which year did the CFL begin requiring teams to attempt 2-point conversions after scoring in a tie-breaking situation?
[ "In which year did the CFL begin requiring teams to attempt 2-point conversions after scoring in a tie-breaking situation?" ]
{ "text": [ "2010" ], "answer_start": [ 396 ] }
gem-squad_v2-train-28714
572e92c5c246551400ce436b
Canadian_football
In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs until it sc...
Which round of tie-breaking is the last possible round in a regular season CFL game?
Which round of tie-breaking is the last possible round in a regular season CFL game?
[ "Which round of tie-breaking is the last possible round in a regular season CFL game?" ]
{ "text": [ "second" ], "answer_start": [ 776 ] }
gem-squad_v2-train-28715
572e92c5c246551400ce436c
Canadian_football
In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs until it sc...
Which CFL games require tie-breaking rounds continue until a winner results?
Which CFL games require tie-breaking rounds continue until a winner results?
[ "Which CFL games require tie-breaking rounds continue until a winner results?" ]
{ "text": [ "playoff or championship" ], "answer_start": [ 874 ] }
gem-squad_v2-train-28716
5a0f93f9decec900184755d9
Canadian_football
In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs until it sc...
After teams have completed their 2 point conversions, who is declared the winner?
After teams have completed their 2 point conversions, who is declared the winner?
[ "After teams have completed their 2 point conversions, who is declared the winner?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28717
5a0f93f9decec900184755da
Canadian_football
In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs until it sc...
If a game is tied at the end of a touchdown, what determines who takes possession?
If a game is tied at the end of a touchdown, what determines who takes possession?
[ "If a game is tied at the end of a touchdown, what determines who takes possession?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28718
5a0f93f9decec900184755db
Canadian_football
In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs until it sc...
After the coin toss if there is no winner during regular season what happens?
After the coin toss if there is no winner during regular season what happens?
[ "After the coin toss if there is no winner during regular season what happens?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28719
5a0f93f9decec900184755dc
Canadian_football
In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs until it sc...
What is a team required to do after having a possession in the 2010 season?
What is a team required to do after having a possession in the 2010 season?
[ "What is a team required to do after having a possession in the 2010 season?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28720
5a0f93f9decec900184755dd
Canadian_football
In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs until it sc...
In the 2010 season if a game is tied what can each team do?
In the 2010 season if a game is tied what can each team do?
[ "In the 2010 season if a game is tied what can each team do?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28721
571a6dbe4faf5e1900b8a9a0
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
Who identified the active substance?
Who identified the active substance?
[ "Who identified the active substance?" ]
{ "text": [ "John Abel" ], "answer_start": [ 545 ] }
gem-squad_v2-train-28722
571a6dbe4faf5e1900b8a9a1
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
Who marketed epinephrine?
Who marketed epinephrine?
[ "Who marketed epinephrine?" ]
{ "text": [ "Parke Davis" ], "answer_start": [ 837 ] }
gem-squad_v2-train-28723
571a6dbe4faf5e1900b8a9a3
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
As an inhaler, what was epinephrine used to treat?
As an inhaler, what was epinephrine used to treat?
[ "As an inhaler, what was epinephrine used to treat?" ]
{ "text": [ "nasal congestion" ], "answer_start": [ 1168 ] }
gem-squad_v2-train-28724
571a6dbe4faf5e1900b8a9a4
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
Who developed the method to obtain epinephrine in a pure state?
Who developed the method to obtain epinephrine in a pure state?
[ "Who developed the method to obtain epinephrine in a pure state?" ]
{ "text": [ "Jokichi Takamine" ], "answer_start": [ 708 ] }
gem-squad_v2-train-28725
571a79d910f8ca1400305084
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
What could epinephrine treat?
What could epinephrine treat?
[ "What could epinephrine treat?" ]
{ "text": [ "nasal congestion" ], "answer_start": [ 1168 ] }
gem-squad_v2-train-28726
571a79d910f8ca1400305085
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
When did epinephrine stop being available in the United States?
When did epinephrine stop being available in the United States?
[ "When did epinephrine stop being available in the United States?" ]
{ "text": [ "2011" ], "answer_start": [ 1061 ] }
gem-squad_v2-train-28727
571a79d910f8ca1400305086
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
What trade name was epinephrine marketed under?
What trade name was epinephrine marketed under?
[ "What trade name was epinephrine marketed under?" ]
{ "text": [ "Adrenalin" ], "answer_start": [ 891 ] }
gem-squad_v2-train-28728
571a79d910f8ca1400305087
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
Who developed the method to get epinephrine in it's pure form?
Who developed the method to get epinephrine in it's pure form?
[ "Who developed the method to get epinephrine in it's pure form?" ]
{ "text": [ "Jokichi Takamine" ], "answer_start": [ 708 ] }
gem-squad_v2-train-28729
571ced8fdd7acb1400e4c1aa
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
In what year was epinephrine discovered?
In what year was epinephrine discovered?
[ "In what year was epinephrine discovered?" ]
{ "text": [ "1897" ], "answer_start": [ 540 ] }
gem-squad_v2-train-28730
571ced8fdd7acb1400e4c1ab
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
What was the trade name of epinephrine?
What was the trade name of epinephrine?
[ "What was the trade name of epinephrine?" ]
{ "text": [ "Adrenalin" ], "answer_start": [ 891 ] }
gem-squad_v2-train-28731
571ced8fdd7acb1400e4c1ac
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
Who first discovered epinephrine?
Who first discovered epinephrine?
[ "Who first discovered epinephrine?" ]
{ "text": [ "John Abel" ], "answer_start": [ 545 ] }
gem-squad_v2-train-28732
571ced8fdd7acb1400e4c1ad
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
What is epinephrine used to treat?
What is epinephrine used to treat?
[ "What is epinephrine used to treat?" ]
{ "text": [ "asthma attacks" ], "answer_start": [ 986 ] }
gem-squad_v2-train-28733
571ced8fdd7acb1400e4c1ae
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
In what year was Primatene Mist no longer sold in the United States?
In what year was Primatene Mist no longer sold in the United States?
[ "In what year was Primatene Mist no longer sold in the United States?" ]
{ "text": [ "2011" ], "answer_start": [ 1061 ] }
gem-squad_v2-train-28734
5ad35451604f3c001a3fdd75
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
Who identified the inactive substance?
Who identified the inactive substance?
[ "Who identified the inactive substance?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28735
5ad35451604f3c001a3fdd76
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
Who marketed Primatene?
Who marketed Primatene?
[ "Who marketed Primatene?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28736
5ad35451604f3c001a3fdd77
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
What trade name was Primatene marketed under?
What trade name was Primatene marketed under?
[ "What trade name was Primatene marketed under?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28737
5ad35451604f3c001a3fdd78
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
As an inhaler, what was Primatene used to treat?
As an inhaler, what was Primatene used to treat?
[ "As an inhaler, what was Primatene used to treat?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28738
5ad35451604f3c001a3fdd79
Pharmaceutical_industry
By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extra...
Who developed the method to obtain Primatene in a pure state?
Who developed the method to obtain Primatene in a pure state?
[ "Who developed the method to obtain Primatene in a pure state?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28739
571a7b594faf5e1900b8a9ce
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
Who developed Amphetamine?
Who developed Amphetamine?
[ "Who developed Amphetamine?" ]
{ "text": [ "Smith, Kline and French" ], "answer_start": [ 628 ] }
gem-squad_v2-train-28740
571a7b594faf5e1900b8a9cf
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
What are common side effects of Amphetamine?
What are common side effects of Amphetamine?
[ "What are common side effects of Amphetamine?" ]
{ "text": [ "sensations of exhilaration and palpitations" ], "answer_start": [ 554 ] }
gem-squad_v2-train-28741
571a7b594faf5e1900b8a9d0
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
When were tricyclic antidepressants developed?
When were tricyclic antidepressants developed?
[ "When were tricyclic antidepressants developed?" ]
{ "text": [ "1960s" ], "answer_start": [ 1101 ] }
gem-squad_v2-train-28742
571a7b594faf5e1900b8a9d1
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
What were some uses for Amphetamine?
What were some uses for Amphetamine?
[ "What were some uses for Amphetamine?" ]
{ "text": [ "narcolepsy, post-encepheletic parkinsonism, and mood elevation in depression and other psychiatric indications" ], "answer_start": [ 775 ] }
gem-squad_v2-train-28743
571a7b594faf5e1900b8a9d2
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
Who synthesized Amphetamine for asthma?
Who synthesized Amphetamine for asthma?
[ "Who synthesized Amphetamine for asthma?" ]
{ "text": [ "Gordon Alles" ], "answer_start": [ 405 ] }
gem-squad_v2-train-28744
571cef645efbb31900334e52
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
Ephedrine was used as an oral medicine for what illness?
Ephedrine was used as an oral medicine for what illness?
[ "Ephedrine was used as an oral medicine for what illness?" ]
{ "text": [ "asthma" ], "answer_start": [ 306 ] }
gem-squad_v2-train-28745
571cef645efbb31900334e53
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
In what year was amphetamine first tested on asthma patients?
In what year was amphetamine first tested on asthma patients?
[ "In what year was amphetamine first tested on asthma patients?" ]
{ "text": [ "1929" ], "answer_start": [ 478 ] }
gem-squad_v2-train-28746
571cef645efbb31900334e54
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
What was the trade name of amphetamine as a nasal decongestant?
What was the trade name of amphetamine as a nasal decongestant?
[ "What was the trade name of amphetamine as a nasal decongestant?" ]
{ "text": [ "Benzedrine Inhaler" ], "answer_start": [ 697 ] }
gem-squad_v2-train-28747
571cef645efbb31900334e55
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
In what year did the American Medical Association approve amphetamine for medical use?
In what year did the American Medical Association approve amphetamine for medical use?
[ "In what year did the American Medical Association approve amphetamine for medical use?" ]
{ "text": [ "1937" ], "answer_start": [ 996 ] }
gem-squad_v2-train-28748
571cef645efbb31900334e56
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
In what decade were tricyclic antidepressants created?
In what decade were tricyclic antidepressants created?
[ "In what decade were tricyclic antidepressants created?" ]
{ "text": [ "1960s" ], "answer_start": [ 1101 ] }
gem-squad_v2-train-28749
5ad355cd604f3c001a3fddad
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
Who developed tricyclics?
Who developed tricyclics?
[ "Who developed tricyclics?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28750
5ad355cd604f3c001a3fddae
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
What are common side effects of tricyclics?
What are common side effects of tricyclics?
[ "What are common side effects of tricyclics?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28751
5ad355cd604f3c001a3fddaf
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
When was the American Medical Association developed?
When was the American Medical Association developed?
[ "When was the American Medical Association developed?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28752
5ad355cd604f3c001a3fddb0
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
What were some uses for the American Medical Association?
What were some uses for the American Medical Association?
[ "What were some uses for the American Medical Association?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28753
5ad355cd604f3c001a3fddb1
Pharmaceutical_industry
While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. Follow...
Who synthesized the American Medical Association for asthma?
Who synthesized the American Medical Association for asthma?
[ "Who synthesized the American Medical Association for asthma?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28754
571a7d3f4faf5e1900b8a9e0
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
What is diabetes caused from?
What is diabetes caused from?
[ "What is diabetes caused from?" ]
{ "text": [ "absence of a substance normally produced by the pancreas" ], "answer_start": [ 113 ] }
gem-squad_v2-train-28755
571a7d3f4faf5e1900b8a9e1
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
Before insulin, what was the life expectancy of diabetics?
Before insulin, what was the life expectancy of diabetics?
[ "Before insulin, what was the life expectancy of diabetics?" ]
{ "text": [ "only a few months" ], "answer_start": [ 1411 ] }
gem-squad_v2-train-28756
571a7d3f4faf5e1900b8a9e2
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
How can diabetes be induced in dogs?
How can diabetes be induced in dogs?
[ "How can diabetes be induced in dogs?" ]
{ "text": [ "surgical removal of the pancreas" ], "answer_start": [ 266 ] }
gem-squad_v2-train-28757
571a7d3f4faf5e1900b8a9e3
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
Who discovered that pancreatic extract reversed symptoms of pancreas removal?
Who discovered that pancreatic extract reversed symptoms of pancreas removal?
[ "Who discovered that pancreatic extract reversed symptoms of pancreas removal?" ]
{ "text": [ "Frederick Banting and his student Charles Best" ], "answer_start": [ 328 ] }
gem-squad_v2-train-28758
571a7d3f4faf5e1900b8a9e4
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
Why was insulin therapy delayed?
Why was insulin therapy delayed?
[ "Why was insulin therapy delayed?" ]
{ "text": [ "difficulties in producing the material in sufficient quantity and with reproducible purity" ], "answer_start": [ 631 ] }
gem-squad_v2-train-28759
571cf17ddd7acb1400e4c1b4
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
Diabetes is caused by the removal of what organ?
Diabetes is caused by the removal of what organ?
[ "Diabetes is caused by the removal of what organ?" ]
{ "text": [ "pancreas" ], "answer_start": [ 161 ] }
gem-squad_v2-train-28760
571cf17ddd7acb1400e4c1b5
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
Left untreated, how long were diabetic patients were expected to live?
Left untreated, how long were diabetic patients were expected to live?
[ "Left untreated, how long were diabetic patients were expected to live?" ]
{ "text": [ "a few months" ], "answer_start": [ 1416 ] }
gem-squad_v2-train-28761
571cf17ddd7acb1400e4c1b6
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
What could be adjusted in a sample of pancreatic extract to produce purer insulin?
What could be adjusted in a sample of pancreatic extract to produce purer insulin?
[ "What could be adjusted in a sample of pancreatic extract to produce purer insulin?" ]
{ "text": [ "pH" ], "answer_start": [ 981 ] }
gem-squad_v2-train-28762
571cf17ddd7acb1400e4c1b7
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
To purify insulin, Banting and Best sought the assistance of what company?
To purify insulin, Banting and Best sought the assistance of what company?
[ "To purify insulin, Banting and Best sought the assistance of what company?" ]
{ "text": [ "Eli Lilly and Co." ], "answer_start": [ 790 ] }
gem-squad_v2-train-28763
571cf17ddd7acb1400e4c1b8
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
Minkowski and von Mering did surgical tests on what animal?
Minkowski and von Mering did surgical tests on what animal?
[ "Minkowski and von Mering did surgical tests on what animal?" ]
{ "text": [ "dogs" ], "answer_start": [ 258 ] }
gem-squad_v2-train-28764
5ad359eb604f3c001a3fde4b
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
What is purification caused from?
What is purification caused from?
[ "What is purification caused from?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28765
5ad359eb604f3c001a3fde4c
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
Before insulin, what was the life expectancy of purification?
Before insulin, what was the life expectancy of purification?
[ "Before insulin, what was the life expectancy of purification?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28766
5ad359eb604f3c001a3fde4d
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
How can purification be induced in dogs?
How can purification be induced in dogs?
[ "How can purification be induced in dogs?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28767
5ad359eb604f3c001a3fde4e
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
Who discovered that pancreatic extract reversed symptoms of purification removal?
Who discovered that pancreatic extract reversed symptoms of purification removal?
[ "Who discovered that pancreatic extract reversed symptoms of purification removal?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28768
5ad359eb604f3c001a3fde4f
Pharmaceutical_industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian pr...
Why was purification therapy delayed?
Why was purification therapy delayed?
[ "Why was purification therapy delayed?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28769
571a7fd610f8ca14003050af
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
What is phenobarbital used for?
What is phenobarbital used for?
[ "What is phenobarbital used for?" ]
{ "text": [ "epilepsy" ], "answer_start": [ 1128 ] }
gem-squad_v2-train-28770
571a7fd610f8ca14003050b0
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
What sleep aid was marketed in 1904?
What sleep aid was marketed in 1904?
[ "What sleep aid was marketed in 1904?" ]
{ "text": [ "Veronal" ], "answer_start": [ 326 ] }
gem-squad_v2-train-28771
571a7fd610f8ca14003050b1
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
What is amphetamine used for today?
What is amphetamine used for today?
[ "What is amphetamine used for today?" ]
{ "text": [ "attention deficit disorder" ], "answer_start": [ 1063 ] }
gem-squad_v2-train-28772
571a7fd610f8ca14003050b2
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
Why was barbiturates and amphetamines restricted?
Why was barbiturates and amphetamines restricted?
[ "Why was barbiturates and amphetamines restricted?" ]
{ "text": [ "addictive properties and abuse potential" ], "answer_start": [ 824 ] }
gem-squad_v2-train-28773
571a7fd610f8ca14003050b3
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
Who discovered a reaction that induced sleep in dogs?
Who discovered a reaction that induced sleep in dogs?
[ "Who discovered a reaction that induced sleep in dogs?" ]
{ "text": [ "Hermann Emil Fischer and Joseph von Mering" ], "answer_start": [ 8 ] }
gem-squad_v2-train-28774
571cf2c5dd7acb1400e4c1be
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
What compound was discovered to induce sleep?
What compound was discovered to induce sleep?
[ "What compound was discovered to induce sleep?" ]
{ "text": [ "diethylbarbituric acid" ], "answer_start": [ 82 ] }
gem-squad_v2-train-28775
571cf2c5dd7acb1400e4c1bf
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
What was the first trade name of diethylbarbituric acid?
What was the first trade name of diethylbarbituric acid?
[ "What was the first trade name of diethylbarbituric acid?" ]
{ "text": [ "Veronal" ], "answer_start": [ 326 ] }
gem-squad_v2-train-28776
571cf2c5dd7acb1400e4c1c0
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
What is phenobarbital mainly used to treat today?
What is phenobarbital mainly used to treat today?
[ "What is phenobarbital mainly used to treat today?" ]
{ "text": [ "epilepsy" ], "answer_start": [ 1128 ] }
gem-squad_v2-train-28777
571cf2c5dd7acb1400e4c1c1
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
In what year was phenobarbital discovered?
In what year was phenobarbital discovered?
[ "In what year was phenobarbital discovered?" ]
{ "text": [ "1911" ], "answer_start": [ 514 ] }
gem-squad_v2-train-28778
571cf2c5dd7acb1400e4c1c2
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
What was Veronal used for when Bayer put it on the market?
What was Veronal used for when Bayer put it on the market?
[ "What was Veronal used for when Bayer put it on the market?" ]
{ "text": [ "sleep aid" ], "answer_start": [ 339 ] }
gem-squad_v2-train-28779
5ad35897604f3c001a3fde2f
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
What is increased awareness used for?
What is increased awareness used for?
[ "What is increased awareness used for?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28780
5ad35897604f3c001a3fde30
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
What acid was marketed in 1904?
What acid was marketed in 1904?
[ "What acid was marketed in 1904?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28781
5ad35897604f3c001a3fde31
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
What is acid used for today?
What is acid used for today?
[ "What is acid used for today?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28782
5ad35897604f3c001a3fde32
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
Why were acids restricted?
Why were acids restricted?
[ "Why were acids restricted? " ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28783
5ad35897604f3c001a3fde33
Pharmaceutical_industry
In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade...
Who discovered an acid reaction?
Who discovered an acid reaction?
[ "Who discovered an acid reaction?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28784
571aa3cb4faf5e1900b8ab8e
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
Who developed Arsphenamine?
Who developed Arsphenamine?
[ "Who developed Arsphenamine?" ]
{ "text": [ "Paul Ehrlich and chemist Alfred Bertheim" ], "answer_start": [ 80 ] }
gem-squad_v2-train-28785
571aa3cb4faf5e1900b8ab8f
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
What was the first effective treatment for Syphilis?
What was the first effective treatment for Syphilis?
[ "What was the first effective treatment for Syphilis?" ]
{ "text": [ "Arsphenamine" ], "answer_start": [ 609 ] }
gem-squad_v2-train-28786
571aa3cb4faf5e1900b8ab90
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
What complications are associated with Syphilis?
What complications are associated with Syphilis?
[ "What complications are associated with Syphilis?" ]
{ "text": [ "severe skin ulceration, neurological damage, and death" ], "answer_start": [ 750 ] }
gem-squad_v2-train-28787
571aa3cb4faf5e1900b8ab91
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
What is Amphetamine's market name?
What is Amphetamine's market name?
[ "What is Amphetamine's market name?" ]
{ "text": [ "Institute of Experimental Therapy" ], "answer_start": [ 128 ] }
gem-squad_v2-train-28788
571aa3cb4faf5e1900b8ab92
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
Where is the Institute of Experimental Therapy located?
Where is the Institute of Experimental Therapy located?
[ "Where is the Institute of Experimental Therapy located?" ]
{ "text": [ "Berlin" ], "answer_start": [ 165 ] }
gem-squad_v2-train-28789
571cf51edd7acb1400e4c1c8
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
What was the name of the first synthetic bacterial drug?
What was the name of the first synthetic bacterial drug?
[ "What was the name of the first synthetic bacterial drug?" ]
{ "text": [ "arsphenamine" ], "answer_start": [ 8 ] }
gem-squad_v2-train-28790
571cf51edd7acb1400e4c1c9
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
Bacterial infections could be treated with medicines containing what kind of dye?
Bacterial infections could be treated with medicines containing what kind of dye?
[ "Bacterial infections could be treated with medicines containing what kind of dye?" ]
{ "text": [ "arsenic" ], "answer_start": [ 355 ] }
gem-squad_v2-train-28791
571cf51edd7acb1400e4c1ca
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
Arsphenamine became the first treatment for what previously incurable disease?
Arsphenamine became the first treatment for what previously incurable disease?
[ "Arsphenamine became the first treatment for what previously incurable disease?" ]
{ "text": [ "syphilis" ], "answer_start": [ 669 ] }
gem-squad_v2-train-28792
571cf51edd7acb1400e4c1cb
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
In what year was arsphenamine discovered?
In what year was arsphenamine discovered?
[ "In what year was arsphenamine discovered?" ]
{ "text": [ "1911" ], "answer_start": [ 3 ] }
gem-squad_v2-train-28793
571cf51edd7acb1400e4c1cc
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
What was the commercial name of arsphenamine?
What was the commercial name of arsphenamine?
[ "What was the commercial name of arsphenamine?" ]
{ "text": [ "Salvarsan" ], "answer_start": [ 212 ] }
gem-squad_v2-train-28794
5ad35bb2604f3c001a3fde7b
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
Who developed commercial ulceration?
Who developed commercial ulceration?
[ "Who developed commercial ulceration?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28795
5ad35bb2604f3c001a3fde7c
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
What was the first effective treatment for Bertheim?
What was the first effective treatment for Bertheim?
[ "What was the first effective treatment for Bertheim?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28796
5ad35bb2604f3c001a3fde7d
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
What complications are associated with Bertheim?
What complications are associated with Bertheim?
[ "What complications are associated with Bertheim?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28797
5ad35bb2604f3c001a3fde7e
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
What is Bertheim's market name?
What is Bertheim's market name?
[ "What is Bertheim's market name?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28798
5ad35bb2604f3c001a3fde7f
Pharmaceutical_industry
In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes...
Where is the Institute of Bertheim located?
Where is the Institute of Bertheim located?
[ "Where is the Institute of Bertheim located?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-28799
571aa8204faf5e1900b8abca
Pharmaceutical_industry
The modern pharmaceutical industry traces its roots to two sources. The first of these were local apothecaries that expanded from their traditional role distributing botanical drugs such as morphine and quinine to wholesale manufacture in the mid 1800s. Rational drug discovery from plants started particularly with the ...
When was Morphine and Quinine first available?
When was Morphine and Quinine first available?
[ "When was Morphine and Quinine first available?" ]
{ "text": [ "mid 1800s" ], "answer_start": [ 243 ] }