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gem-squad_v2-train-29200
5ad39ae3604f3c001a3fe885
Pharmaceutical_industry
An investigation by ProPublica found that at least 21 doctors have been paid more than $500,000 for speeches and consulting by drugs manufacturers since 2009, with half of the top earners working in psychiatry, and about $2 billion in total paid to doctors for such services. AstraZeneca, Johnson & Johnson and Eli Lilly...
Who conducted an investigation on drugs?
Who conducted an investigation on drugs?
[ "Who conducted an investigation on drugs?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29201
5ad39ae3604f3c001a3fe886
Pharmaceutical_industry
An investigation by ProPublica found that at least 21 doctors have been paid more than $500,000 for speeches and consulting by drugs manufacturers since 2009, with half of the top earners working in psychiatry, and about $2 billion in total paid to doctors for such services. AstraZeneca, Johnson & Johnson and Eli Lilly...
Billions of drugs have been paid why which companies?
Billions of drugs have been paid why which companies?
[ "Billions of drugs have been paid why which companies?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29202
5ad39ae3604f3c001a3fe887
Pharmaceutical_industry
An investigation by ProPublica found that at least 21 doctors have been paid more than $500,000 for speeches and consulting by drugs manufacturers since 2009, with half of the top earners working in psychiatry, and about $2 billion in total paid to doctors for such services. AstraZeneca, Johnson & Johnson and Eli Lilly...
How much was discovered to have been paid to drug companies by doctors?
How much was discovered to have been paid to drug companies by doctors?
[ "How much was discovered to have been paid to drug companies by doctors?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29203
5ad39ae3604f3c001a3fe888
Pharmaceutical_industry
An investigation by ProPublica found that at least 21 doctors have been paid more than $500,000 for speeches and consulting by drugs manufacturers since 2009, with half of the top earners working in psychiatry, and about $2 billion in total paid to doctors for such services. AstraZeneca, Johnson & Johnson and Eli Lilly...
What was the reason these doctors have to pay fines?
What was the reason these doctors have to pay fines?
[ "What was the reason these doctors have to pay fines?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29204
5ad39ae3604f3c001a3fe889
Pharmaceutical_industry
An investigation by ProPublica found that at least 21 doctors have been paid more than $500,000 for speeches and consulting by drugs manufacturers since 2009, with half of the top earners working in psychiatry, and about $2 billion in total paid to doctors for such services. AstraZeneca, Johnson & Johnson and Eli Lilly...
How many companies have been paid by various doctors?
How many companies have been paid by various doctors?
[ "How many companies have been paid by various doctors?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29205
571af72f9499d21900609bbd
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
Why are collaborative agreements important?
Why are collaborative agreements important?
[ "Why are collaborative agreements important?" ]
{ "text": [ "to explore the potential of new drug substances" ], "answer_start": [ 455 ] }
gem-squad_v2-train-29206
571af72f9499d21900609bbe
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
How do large corporations show vertical integration?
How do large corporations show vertical integration?
[ "How do large corporations show vertical integration?" ]
{ "text": [ "participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution" ], "answer_start": [ 70 ] }
gem-squad_v2-train-29207
571af72f9499d21900609bbf
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
What are large companies relying on outside organizations for?
What are large companies relying on outside organizations for?
[ "What are large companies relying on outside organizations for?" ]
{ "text": [ "to manage drug development" ], "answer_start": [ 595 ] }
gem-squad_v2-train-29208
571af72f9499d21900609bc0
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
What are smaller organizations responsible for?
What are smaller organizations responsible for?
[ "What are smaller organizations responsible for?" ]
{ "text": [ "focus on a specific aspect such as discovering drug candidates or developing formulations" ], "answer_start": [ 255 ] }
gem-squad_v2-train-29209
571d29cf5efbb31900334eba
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
What type of integration do large corporations often do?
What type of integration do large corporations often do?
[ "What type of integration do large corporations often do?" ]
{ "text": [ "vertical" ], "answer_start": [ 48 ] }
gem-squad_v2-train-29210
571d29cf5efbb31900334ebb
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
What type of integration do smaller organizations do?
What type of integration do smaller organizations do?
[ "What type of integration do smaller organizations do?" ]
{ "text": [ "a specific aspect" ], "answer_start": [ 264 ] }
gem-squad_v2-train-29211
571d29cf5efbb31900334ebc
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
What type of agreements are made to research potential new drugs?
What type of agreements are made to research potential new drugs?
[ "What type of agreements are made to research potential new drugs?" ]
{ "text": [ "collaborative agreements" ], "answer_start": [ 353 ] }
gem-squad_v2-train-29212
571d29cf5efbb31900334ebd
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
What type of organizations are multinational corporations increasingly rely on?
What type of organizations are multinational corporations increasingly rely on?
[ "What type of organizations are multinational corporations increasingly rely on?" ]
{ "text": [ "contract research" ], "answer_start": [ 563 ] }
gem-squad_v2-train-29213
5ad39125604f3c001a3fe665
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
Why is collaborative distribution important?
Why is collaborative distribution important?
[ "Why is collaborative distribution important?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29214
5ad39125604f3c001a3fe666
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
How do large corporations show multi-nationals integration?
How do large corporations show multi-nationals integration?
[ "How do large corporations show multi-nationals integration?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29215
5ad39125604f3c001a3fe667
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
What are large companies relying on outside marketing for?
What are large companies relying on outside marketing for?
[ "What are large companies relying on outside marketing for?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29216
5ad39125604f3c001a3fe668
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
What are smaller drugs responsible for?
What are smaller drugs responsible for?
[ "What are smaller drugs responsible for?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29217
5ad39125604f3c001a3fe669
Pharmaceutical_industry
Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or...
What type of integration do large drugs often do?
What type of integration do large drugs often do?
[ "What type of integration do large drugs often do?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29218
571af86f32177014007ea002
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
Who is the core guide?
Who is the core guide?
[ "Who is the core guide?" ]
{ "text": [ "The British National Formulary" ], "answer_start": [ 501 ] }
gem-squad_v2-train-29219
571af86f32177014007ea003
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
Who is responsible for approving drugs in the United Kingdom?
Who is responsible for approving drugs in the United Kingdom?
[ "Who is responsible for approving drugs in the United Kingdom?" ]
{ "text": [ "Medicines and Healthcare Products Regulatory Agency" ], "answer_start": [ 15 ] }
gem-squad_v2-train-29220
571af86f32177014007ea004
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
After an approval in the United States, when does an approval occur in the United Kingdom and other countries?
After an approval in the United States, when does an approval occur in the United Kingdom and other countries?
[ "After an approval in the United States, when does an approval occur in the United Kingdom and other countries?" ]
{ "text": [ "comes later" ], "answer_start": [ 264 ] }
gem-squad_v2-train-29221
571af86f32177014007ea005
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
Who decides how NHS will allow drugs?
Who decides how NHS will allow drugs?
[ "Who decides how NHS will allow drugs?" ]
{ "text": [ "National Institute for Health and Care Excellence (NICE)" ], "answer_start": [ 312 ] }
gem-squad_v2-train-29222
571af86f32177014007ea006
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
Who does the evaluations for drugs in the United Kingdom?
Who does the evaluations for drugs in the United Kingdom?
[ "Who does the evaluations for drugs in the United Kingdom?" ]
{ "text": [ "European Medicines Agency" ], "answer_start": [ 128 ] }
gem-squad_v2-train-29223
571d2a97dd7acb1400e4c22c
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
What UK firm approves pharmaceutical drugs?
What UK firm approves pharmaceutical drugs?
[ "What UK firm approves pharmaceutical drugs?" ]
{ "text": [ "Medicines and Healthcare Products Regulatory Agency" ], "answer_start": [ 15 ] }
gem-squad_v2-train-29224
571d2a97dd7acb1400e4c22d
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
What UK organization evaluates drugs?
What UK organization evaluates drugs?
[ "What UK organization evaluates drugs? " ]
{ "text": [ "European Medicines Agency" ], "answer_start": [ 128 ] }
gem-squad_v2-train-29225
571d2a97dd7acb1400e4c22e
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
What firm in England and Wales decides if the NHS allows drugs?
What firm in England and Wales decides if the NHS allows drugs?
[ "What firm in England and Wales decides if the NHS allows drugs?" ]
{ "text": [ "National Institute for Health and Care Excellence" ], "answer_start": [ 312 ] }
gem-squad_v2-train-29226
571d2a97dd7acb1400e4c22f
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
What is the name of the core guide for pharmacists and clinicians?
What is the name of the core guide for pharmacists and clinicians?
[ "What is the name of the core guide for pharmacists and clinicians?" ]
{ "text": [ "British National Formulary" ], "answer_start": [ 505 ] }
gem-squad_v2-train-29227
5ad3a053604f3c001a3fe995
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
Who is the core clinician?
Who is the core clinician?
[ "Who is the core clinician?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29228
5ad3a053604f3c001a3fe996
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
Who is responsible for approving drugs in the NHS?
Who is responsible for approving drugs in the NHS?
[ "Who is responsible for approving drugs in the NHS?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29229
5ad3a053604f3c001a3fe997
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
After an approval in the UK, when does an approval occur in the NHS and other countries?
After an approval in the UK, when does an approval occur in the NHS and other countries?
[ "After an approval in the UK, when does an approval occur in the NHS and other countries?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29230
5ad3a053604f3c001a3fe998
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
Who decides how the USA will allow drugs?
Who decides how the USA will allow drugs?
[ "Who decides how the USA will allow drugs?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29231
5ad3a053604f3c001a3fe999
Pharmaceutical_industry
In the UK, the Medicines and Healthcare Products Regulatory Agency approves drugs for use, though the evaluation is done by the European Medicines Agency, an agency of the European Union based in London. Normally an approval in the UK and other European countries comes later than one in the USA. Then it is the National...
Who does the evaluations for drugs in the United States?
Who does the evaluations for drugs in the United States?
[ "Who does the evaluations for drugs in the United States?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29232
571af9329499d21900609bc5
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
What is subject to the Orphan Drug Act?
What is subject to the Orphan Drug Act?
[ "What is subject to the Orphan Drug Act?" ]
{ "text": [ "diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances" ], "answer_start": [ 129 ] }
gem-squad_v2-train-29233
571af9329499d21900609bc6
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
What is given to companies who develop drugs for "orphan diseases"?
What is given to companies who develop drugs for "orphan diseases"?
[ "What is given to companies who develop drugs for \"orphan diseases\"?" ]
{ "text": [ "tax reductions, fee waivers, and market exclusivity on that drug for a limited time (seven years), regardless of whether the drug is protected by patents" ], "answer_start": [ 426 ] }
gem-squad_v2-train-29234
571af9329499d21900609bc7
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
Why are these companies rewarded?
Why are these companies rewarded?
[ "Why are these companies rewarded?" ]
{ "text": [ "Because medical research and development of drugs to treat such diseases is financially disadvantageous" ], "answer_start": [ 282 ] }
gem-squad_v2-train-29235
571d2b4ddd7acb1400e4c234
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
What is a term for rare diseases in some territories?
What is a term for rare diseases in some territories?
[ "What is a term for rare diseases in some territories?" ]
{ "text": [ "orphan diseases" ], "answer_start": [ 52 ] }
gem-squad_v2-train-29236
571d2b4ddd7acb1400e4c235
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
What size of disease populations are subject to the Orphan Drug Act?
What size of disease populations are subject to the Orphan Drug Act?
[ "What size of disease populations are subject to the Orphan Drug Act?" ]
{ "text": [ "fewer than 200,000 patients" ], "answer_start": [ 148 ] }
gem-squad_v2-train-29237
571d2b4ddd7acb1400e4c236
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
What is one financial benefit to researching orphan drugs?
What is one financial benefit to researching orphan drugs?
[ "What is one financial benefit to researching orphan drugs?" ]
{ "text": [ "tax reductions" ], "answer_start": [ 426 ] }
gem-squad_v2-train-29238
571d2b4ddd7acb1400e4c237
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
What is the length of time of market exclusivity of an orphan drug?
What is the length of time of market exclusivity of an orphan drug?
[ "What is the length of time of market exclusivity of an orphan drug?" ]
{ "text": [ "seven years" ], "answer_start": [ 511 ] }
gem-squad_v2-train-29239
5ad3a4c6604f3c001a3fea95
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
What is subject to patients in the United States?
What is subject to patients in the United States?
[ "What is subject to patients in the United States?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29240
5ad3a4c6604f3c001a3fea96
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
What is given to companies who develop rules for "orphan diseases"?
What is given to companies who develop rules for "orphan diseases"?
[ "What is given to companies who develop rules for \"orphan diseases\"?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29241
5ad3a4c6604f3c001a3fea97
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
Why are these rules rewarded?
Why are these rules rewarded?
[ "Why are these rules rewarded?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29242
5ad3a4c6604f3c001a3fea98
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
What is a term for rare rules in some territories?
What is a term for rare rules in some territories?
[ "What is a term for rare rules in some territories?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29243
5ad3a4c6604f3c001a3fea99
Pharmaceutical_industry
There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act. Because medical research and developme...
What size of disease populations are subject to patents?
What size of disease populations are subject to patents?
[ "What size of disease populations are subject to patents?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29244
571af9889499d21900609bcb
Pharmaceutical_industry
Ben Goldacre has argued that regulators – such as the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK, or the Food and Drug Administration (FDA) in the United States – advance the interests of the drug companies rather than the interests of the public due to revolving door exchange of employees bet...
Who argued against regulators?
Who argued against regulators?
[ "Who argued against regulators?" ]
{ "text": [ "Ben Goldacre" ], "answer_start": [ 0 ] }
gem-squad_v2-train-29245
571d3ae3dd7acb1400e4c25c
Pharmaceutical_industry
Ben Goldacre has argued that regulators – such as the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK, or the Food and Drug Administration (FDA) in the United States – advance the interests of the drug companies rather than the interests of the public due to revolving door exchange of employees bet...
Who argued that drug regulators were greater serving the interests of the drug companies than the patients?
Who argued that drug regulators were greater serving the interests of the drug companies than the patients?
[ "Who argued that drug regulators were greater serving the interests of the drug companies than the patients?" ]
{ "text": [ "Ben Goldacre" ], "answer_start": [ 0 ] }
gem-squad_v2-train-29246
571d3ae3dd7acb1400e4c25d
Pharmaceutical_industry
Ben Goldacre has argued that regulators – such as the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK, or the Food and Drug Administration (FDA) in the United States – advance the interests of the drug companies rather than the interests of the public due to revolving door exchange of employees bet...
The business friendships between which parties have been criticized?
The business friendships between which parties have been criticized?
[ "The business friendships between which parties have been criticized?" ]
{ "text": [ "regulator and company employees" ], "answer_start": [ 389 ] }
gem-squad_v2-train-29247
571d3ae3dd7acb1400e4c25e
Pharmaceutical_industry
Ben Goldacre has argued that regulators – such as the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK, or the Food and Drug Administration (FDA) in the United States – advance the interests of the drug companies rather than the interests of the public due to revolving door exchange of employees bet...
Goldacre argued that which party didn't require that new drugs be improved at all?
Goldacre argued that which party didn't require that new drugs be improved at all?
[ "Goldacre argued that which party didn't require that new drugs be improved at all?" ]
{ "text": [ "regulators" ], "answer_start": [ 437 ] }
gem-squad_v2-train-29248
5ad3ad2f604f3c001a3febe5
Pharmaceutical_industry
Ben Goldacre has argued that regulators – such as the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK, or the Food and Drug Administration (FDA) in the United States – advance the interests of the drug companies rather than the interests of the public due to revolving door exchange of employees bet...
Who argued against the public?
Who argued against the public?
[ "Who argued against the public?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29249
5ad3ad2f604f3c001a3febe6
Pharmaceutical_industry
Ben Goldacre has argued that regulators – such as the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK, or the Food and Drug Administration (FDA) in the United States – advance the interests of the drug companies rather than the interests of the public due to revolving door exchange of employees bet...
Who argued that drug regulators were greater serving the interests of patients than the drug companies?
Who argued that drug regulators were greater serving the interests of patients than the drug companies?
[ "Who argued that drug regulators were greater serving the interests of patients than the drug companies?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29250
5ad3ad2f604f3c001a3febe7
Pharmaceutical_industry
Ben Goldacre has argued that regulators – such as the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK, or the Food and Drug Administration (FDA) in the United States – advance the interests of the drug companies rather than the interests of the public due to revolving door exchange of employees bet...
The business friendships between which parties have been praised?
The business friendships between which parties have been praised?
[ "The business friendships between which parties have been praised?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29251
5ad3ad2f604f3c001a3febe8
Pharmaceutical_industry
Ben Goldacre has argued that regulators – such as the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK, or the Food and Drug Administration (FDA) in the United States – advance the interests of the drug companies rather than the interests of the public due to revolving door exchange of employees bet...
The FDA argued that which party didn't require that new drugs be improved at all?
The FDA argued that which party didn't require that new drugs be improved at all?
[ "The FDA argued that which party didn't require that new drugs be improved at all?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29252
5ad3ad2f604f3c001a3febe9
Pharmaceutical_industry
Ben Goldacre has argued that regulators – such as the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK, or the Food and Drug Administration (FDA) in the United States – advance the interests of the drug companies rather than the interests of the public due to revolving door exchange of employees bet...
Who argues that regulators do not require that new regulators offer an improvement?
Who argues that regulators do not require that new regulators offer an improvement?
[ "Who argues that regulators do not require that new regulators offer an improvement?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29253
571d2c3b5efbb31900334ec2
Pharmaceutical_industry
In many non-US western countries a 'fourth hurdle' of cost effectiveness analysis has developed before new technologies can be provided. This focuses on the efficiency (in terms of the cost per QALY) of the technologies in question rather than their efficacy. In England and Wales NICE decides whether and in what circum...
NICE decides the availability of drugs in which two countries?
NICE decides the availability of drugs in which two countries?
[ "NICE decides the availability of drugs in which two countries?" ]
{ "text": [ "England and Wales" ], "answer_start": [ 263 ] }
gem-squad_v2-train-29254
571d2c3b5efbb31900334ec3
Pharmaceutical_industry
In many non-US western countries a 'fourth hurdle' of cost effectiveness analysis has developed before new technologies can be provided. This focuses on the efficiency (in terms of the cost per QALY) of the technologies in question rather than their efficacy. In England and Wales NICE decides whether and in what circum...
What is the name of the organization in Scotland that decides the availability of drugs?
What is the name of the organization in Scotland that decides the availability of drugs?
[ "What is the name of the organization in Scotland that decides the availability of drugs?" ]
{ "text": [ "Scottish Medicines Consortium" ], "answer_start": [ 429 ] }
gem-squad_v2-train-29255
571d2c3b5efbb31900334ec4
Pharmaceutical_industry
In many non-US western countries a 'fourth hurdle' of cost effectiveness analysis has developed before new technologies can be provided. This focuses on the efficiency (in terms of the cost per QALY) of the technologies in question rather than their efficacy. In England and Wales NICE decides whether and in what circum...
What threshold must a drug pass before it is approved?
What threshold must a drug pass before it is approved?
[ "What threshold must a drug pass before it is approved?" ]
{ "text": [ "cost-effectiveness" ], "answer_start": [ 575 ] }
gem-squad_v2-train-29256
5ad3a314604f3c001a3fea45
Pharmaceutical_industry
In many non-US western countries a 'fourth hurdle' of cost effectiveness analysis has developed before new technologies can be provided. This focuses on the efficiency (in terms of the cost per QALY) of the technologies in question rather than their efficacy. In England and Wales NICE decides whether and in what circum...
QALY decides the availability of drugs in which two countries?
QALY decides the availability of drugs in which two countries?
[ "QALY decides the availability of drugs in which two countries?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29257
5ad3a314604f3c001a3fea46
Pharmaceutical_industry
In many non-US western countries a 'fourth hurdle' of cost effectiveness analysis has developed before new technologies can be provided. This focuses on the efficiency (in terms of the cost per QALY) of the technologies in question rather than their efficacy. In England and Wales NICE decides whether and in what circum...
What is the name of the organization in Wales that decides the availability of drugs?
What is the name of the organization in Wales that decides the availability of drugs?
[ "What is the name of the organization in Wales that decides the availability of drugs?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29258
5ad3a314604f3c001a3fea47
Pharmaceutical_industry
In many non-US western countries a 'fourth hurdle' of cost effectiveness analysis has developed before new technologies can be provided. This focuses on the efficiency (in terms of the cost per QALY) of the technologies in question rather than their efficacy. In England and Wales NICE decides whether and in what circum...
What threshold must a Wales pass before it is approved?
What threshold must a Wales pass before it is approved?
[ "What threshold must a Wales pass before it is approved?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29259
5ad3a314604f3c001a3fea48
Pharmaceutical_industry
In many non-US western countries a 'fourth hurdle' of cost effectiveness analysis has developed before new technologies can be provided. This focuses on the efficiency (in terms of the cost per QALY) of the technologies in question rather than their efficacy. In England and Wales NICE decides whether and in what circum...
Where does QALY decide whether decide in what circumstances drugs and technologies will be made available?
Where does QALY decide whether decide in what circumstances drugs and technologies will be made available?
[ "Where does QALY decide whether decide in what circumstances drugs and technologies will be made available?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29260
5ad3a314604f3c001a3fea49
Pharmaceutical_industry
In many non-US western countries a 'fourth hurdle' of cost effectiveness analysis has developed before new technologies can be provided. This focuses on the efficiency (in terms of the cost per QALY) of the technologies in question rather than their efficacy. In England and Wales NICE decides whether and in what circum...
What must the NHS do in order to be approved?
What must the NHS do in order to be approved?
[ "What must the NHS do in order to be approved?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29261
571d2ccfdd7acb1400e4c23c
Pharmaceutical_industry
The top ten best-selling drugs of 2013 totaled $75.6 billion in sales, with the anti-inflammatory drug Humira being the best-selling drug worldwide at $10.7 billion in sales. The second and third best selling were Enbrel and Remicade, respectively. The top three best-selling drugs in the United States in 2013 were Abil...
How much money did the top ten bestselling drugs make in 2013?
How much money did the top ten bestselling drugs make in 2013?
[ "How much money did the top ten bestselling drugs make in 2013?" ]
{ "text": [ "$75.6 billion" ], "answer_start": [ 47 ] }
gem-squad_v2-train-29262
571d2ccfdd7acb1400e4c23d
Pharmaceutical_industry
The top ten best-selling drugs of 2013 totaled $75.6 billion in sales, with the anti-inflammatory drug Humira being the best-selling drug worldwide at $10.7 billion in sales. The second and third best selling were Enbrel and Remicade, respectively. The top three best-selling drugs in the United States in 2013 were Abil...
What was the name of the top-selling anti-inflammatory drug in 2013?
What was the name of the top-selling anti-inflammatory drug in 2013?
[ "What was the name of the top-selling anti-inflammatory drug in 2013?" ]
{ "text": [ "Humira" ], "answer_start": [ 103 ] }
gem-squad_v2-train-29263
571d2ccfdd7acb1400e4c23e
Pharmaceutical_industry
The top ten best-selling drugs of 2013 totaled $75.6 billion in sales, with the anti-inflammatory drug Humira being the best-selling drug worldwide at $10.7 billion in sales. The second and third best selling were Enbrel and Remicade, respectively. The top three best-selling drugs in the United States in 2013 were Abil...
What was the bestselling drug in history?
What was the bestselling drug in history?
[ "What was the bestselling drug in history?" ]
{ "text": [ "Lipitor" ], "answer_start": [ 415 ] }
gem-squad_v2-train-29264
571d2ccfdd7acb1400e4c23f
Pharmaceutical_industry
The top ten best-selling drugs of 2013 totaled $75.6 billion in sales, with the anti-inflammatory drug Humira being the best-selling drug worldwide at $10.7 billion in sales. The second and third best selling were Enbrel and Remicade, respectively. The top three best-selling drugs in the United States in 2013 were Abil...
How much money did Lipitor make before the patent expired?
How much money did Lipitor make before the patent expired?
[ "How much money did Lipitor make before the patent expired?" ]
{ "text": [ "$141 billion" ], "answer_start": [ 465 ] }
gem-squad_v2-train-29265
571d2ccfdd7acb1400e4c240
Pharmaceutical_industry
The top ten best-selling drugs of 2013 totaled $75.6 billion in sales, with the anti-inflammatory drug Humira being the best-selling drug worldwide at $10.7 billion in sales. The second and third best selling were Enbrel and Remicade, respectively. The top three best-selling drugs in the United States in 2013 were Abil...
In what year did Pfizer's patent over Lipitor expire?
In what year did Pfizer's patent over Lipitor expire?
[ "In what year did Pfizer's patent over Lipitor expire?" ]
{ "text": [ "2011" ], "answer_start": [ 545 ] }
gem-squad_v2-train-29266
5ad3a5d0604f3c001a3feaa9
Pharmaceutical_industry
The top ten best-selling drugs of 2013 totaled $75.6 billion in sales, with the anti-inflammatory drug Humira being the best-selling drug worldwide at $10.7 billion in sales. The second and third best selling were Enbrel and Remicade, respectively. The top three best-selling drugs in the United States in 2013 were Abil...
How much money did the top ten bestselling drugs make in 2011?
How much money did the top ten bestselling drugs make in 2011?
[ "How much money did the top ten bestselling drugs make in 2011?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29267
5ad3a5d0604f3c001a3feaaa
Pharmaceutical_industry
The top ten best-selling drugs of 2013 totaled $75.6 billion in sales, with the anti-inflammatory drug Humira being the best-selling drug worldwide at $10.7 billion in sales. The second and third best selling were Enbrel and Remicade, respectively. The top three best-selling drugs in the United States in 2013 were Abil...
What was the name of the top-selling anti-inflammatory drug in 2011?
What was the name of the top-selling anti-inflammatory drug in 2011?
[ "What was the name of the top-selling anti-inflammatory drug in 2011?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29268
5ad3a5d0604f3c001a3feaab
Pharmaceutical_industry
The top ten best-selling drugs of 2013 totaled $75.6 billion in sales, with the anti-inflammatory drug Humira being the best-selling drug worldwide at $10.7 billion in sales. The second and third best selling were Enbrel and Remicade, respectively. The top three best-selling drugs in the United States in 2013 were Abil...
What was the bestselling drug in 2011?
What was the bestselling drug in 2011?
[ "What was the bestselling drug in 2011?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29269
5ad3a5d0604f3c001a3feaac
Pharmaceutical_industry
The top ten best-selling drugs of 2013 totaled $75.6 billion in sales, with the anti-inflammatory drug Humira being the best-selling drug worldwide at $10.7 billion in sales. The second and third best selling were Enbrel and Remicade, respectively. The top three best-selling drugs in the United States in 2013 were Abil...
How much money did Lipitor make after the patent expired?
How much money did Lipitor make after the patent expired?
[ "How much money did Lipitor make after the patent expired?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29270
5ad3a5d0604f3c001a3feaad
Pharmaceutical_industry
The top ten best-selling drugs of 2013 totaled $75.6 billion in sales, with the anti-inflammatory drug Humira being the best-selling drug worldwide at $10.7 billion in sales. The second and third best selling were Enbrel and Remicade, respectively. The top three best-selling drugs in the United States in 2013 were Abil...
In what year did Humira's patent over Lipitor expire?
In what year did Humira's patent over Lipitor expire?
[ "In what year did Humira's patent over Lipitor expire?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29271
571d2dbf5efbb31900334ec8
Pharmaceutical_industry
Depending on a number of considerations, a company may apply for and be granted a patent for the drug, or the process of producing the drug, granting exclusivity rights typically for about 20 years. However, only after rigorous study and testing, which takes 10 to 15 years on average, will governmental authorities gran...
How long do drug exclusivity rights usually last?
How long do drug exclusivity rights usually last?
[ "How long do drug exclusivity rights usually last?" ]
{ "text": [ "20 years" ], "answer_start": [ 189 ] }
gem-squad_v2-train-29272
571d2dbf5efbb31900334ec9
Pharmaceutical_industry
Depending on a number of considerations, a company may apply for and be granted a patent for the drug, or the process of producing the drug, granting exclusivity rights typically for about 20 years. However, only after rigorous study and testing, which takes 10 to 15 years on average, will governmental authorities gran...
Governments grant permission to market drugs after how many years?
Governments grant permission to market drugs after how many years?
[ "Governments grant permission to market drugs after how many years?" ]
{ "text": [ "10 to 15 years on average" ], "answer_start": [ 259 ] }
gem-squad_v2-train-29273
571d2dbf5efbb31900334eca
Pharmaceutical_industry
Depending on a number of considerations, a company may apply for and be granted a patent for the drug, or the process of producing the drug, granting exclusivity rights typically for about 20 years. However, only after rigorous study and testing, which takes 10 to 15 years on average, will governmental authorities gran...
What enables a drug's owner to recover R&D costs?
What enables a drug's owner to recover R&D costs?
[ "What enables a drug's owner to recover R&D costs?" ]
{ "text": [ "Patent protection" ], "answer_start": [ 378 ] }
gem-squad_v2-train-29274
571d2dbf5efbb31900334ecb
Pharmaceutical_industry
Depending on a number of considerations, a company may apply for and be granted a patent for the drug, or the process of producing the drug, granting exclusivity rights typically for about 20 years. However, only after rigorous study and testing, which takes 10 to 15 years on average, will governmental authorities gran...
What kind of drug is produced by competitors once a patent expires?
What kind of drug is produced by competitors once a patent expires?
[ "What kind of drug is produced by competitors once a patent expires?" ]
{ "text": [ "generic" ], "answer_start": [ 578 ] }
gem-squad_v2-train-29275
571d2dbf5efbb31900334ecc
Pharmaceutical_industry
Depending on a number of considerations, a company may apply for and be granted a patent for the drug, or the process of producing the drug, granting exclusivity rights typically for about 20 years. However, only after rigorous study and testing, which takes 10 to 15 years on average, will governmental authorities gran...
What decade was the pharmaceutical industry's "golden era"?
What decade was the pharmaceutical industry's "golden era"?
[ "What decade was the pharmaceutical industry's \"golden era\"?" ]
{ "text": [ "1990s" ], "answer_start": [ 1034 ] }
gem-squad_v2-train-29276
5ad3a6d2604f3c001a3feabf
Pharmaceutical_industry
Depending on a number of considerations, a company may apply for and be granted a patent for the drug, or the process of producing the drug, granting exclusivity rights typically for about 20 years. However, only after rigorous study and testing, which takes 10 to 15 years on average, will governmental authorities gran...
How long do company exclusivity rights usually last?
How long do company exclusivity rights usually last?
[ "How long do company exclusivity rights usually last?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29277
5ad3a6d2604f3c001a3feac0
Pharmaceutical_industry
Depending on a number of considerations, a company may apply for and be granted a patent for the drug, or the process of producing the drug, granting exclusivity rights typically for about 20 years. However, only after rigorous study and testing, which takes 10 to 15 years on average, will governmental authorities gran...
Governments grant permission to market companies after how many years?
Governments grant permission to market companies after how many years?
[ "Governments grant permission to market companies after how many years?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29278
5ad3a6d2604f3c001a3feac1
Pharmaceutical_industry
Depending on a number of considerations, a company may apply for and be granted a patent for the drug, or the process of producing the drug, granting exclusivity rights typically for about 20 years. However, only after rigorous study and testing, which takes 10 to 15 years on average, will governmental authorities gran...
What enables a drug's owner to recover patent costs?
What enables a drug's owner to recover patent costs?
[ "What enables a drug's owner to recover patent costs?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29279
5ad3a6d2604f3c001a3feac2
Pharmaceutical_industry
Depending on a number of considerations, a company may apply for and be granted a patent for the drug, or the process of producing the drug, granting exclusivity rights typically for about 20 years. However, only after rigorous study and testing, which takes 10 to 15 years on average, will governmental authorities gran...
What kind of drug is produced by competitors once an industry expires?
What kind of drug is produced by competitors once an industry expires?
[ "What kind of drug is produced by competitors once an industry expires?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29280
5ad3a6d2604f3c001a3feac3
Pharmaceutical_industry
Depending on a number of considerations, a company may apply for and be granted a patent for the drug, or the process of producing the drug, granting exclusivity rights typically for about 20 years. However, only after rigorous study and testing, which takes 10 to 15 years on average, will governmental authorities gran...
What decade was the pharmaceutical industry's "drug era"?
What decade was the pharmaceutical industry's "drug era"?
[ "What decade was the pharmaceutical industry's \"drug era\"?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29281
571d2eafdd7acb1400e4c246
Pharmaceutical_industry
In the United States, new pharmaceutical products must be approved by the Food and Drug Administration (FDA) as being both safe and effective. This process generally involves submission of an Investigational New Drug filing with sufficient pre-clinical data to support proceeding with human trials. Following IND approva...
The safety and efficacy of new drugs must be approved by what organization in the US?
The safety and efficacy of new drugs must be approved by what organization in the US?
[ "The safety and efficacy of new drugs must be approved by what organization in the US?" ]
{ "text": [ "Food and Drug Administration" ], "answer_start": [ 74 ] }
gem-squad_v2-train-29282
571d2eafdd7acb1400e4c247
Pharmaceutical_industry
In the United States, new pharmaceutical products must be approved by the Food and Drug Administration (FDA) as being both safe and effective. This process generally involves submission of an Investigational New Drug filing with sufficient pre-clinical data to support proceeding with human trials. Following IND approva...
What type of filing is used before beginning human trials?
What type of filing is used before beginning human trials?
[ "What type of filing is used before beginning human trials?" ]
{ "text": [ "Investigational New Drug" ], "answer_start": [ 192 ] }
gem-squad_v2-train-29283
571d2eafdd7acb1400e4c248
Pharmaceutical_industry
In the United States, new pharmaceutical products must be approved by the Food and Drug Administration (FDA) as being both safe and effective. This process generally involves submission of an Investigational New Drug filing with sufficient pre-clinical data to support proceeding with human trials. Following IND approva...
How many phases of human trials may be done after IND approval?
How many phases of human trials may be done after IND approval?
[ "How many phases of human trials may be done after IND approval?" ]
{ "text": [ "three" ], "answer_start": [ 323 ] }
gem-squad_v2-train-29284
571d2eafdd7acb1400e4c249
Pharmaceutical_industry
In the United States, new pharmaceutical products must be approved by the Food and Drug Administration (FDA) as being both safe and effective. This process generally involves submission of an Investigational New Drug filing with sufficient pre-clinical data to support proceeding with human trials. Following IND approva...
What type of application is filed after completing three phases of human trials?
What type of application is filed after completing three phases of human trials?
[ "What type of application is filed after completing three phases of human trials?" ]
{ "text": [ "New Drug Application" ], "answer_start": [ 667 ] }
gem-squad_v2-train-29285
571d2eafdd7acb1400e4c24a
Pharmaceutical_industry
In the United States, new pharmaceutical products must be approved by the Food and Drug Administration (FDA) as being both safe and effective. This process generally involves submission of an Investigational New Drug filing with sufficient pre-clinical data to support proceeding with human trials. Following IND approva...
What type of risk assessment results in approving the drug to go on the market?
What type of risk assessment results in approving the drug to go on the market?
[ "What type of risk assessment results in approving the drug to go on the market?" ]
{ "text": [ "positive benefit-risk" ], "answer_start": [ 776 ] }
gem-squad_v2-train-29286
5ad39f27604f3c001a3fe941
Pharmaceutical_industry
In the United States, new pharmaceutical products must be approved by the Food and Drug Administration (FDA) as being both safe and effective. This process generally involves submission of an Investigational New Drug filing with sufficient pre-clinical data to support proceeding with human trials. Following IND approva...
What organization in the US must approve the safety and efficacy of testing?
What organization in the US must approve the safety and efficacy of testing?
[ "What organization in the US must approve the safety and efficacy of testing?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29287
5ad39f27604f3c001a3fe942
Pharmaceutical_industry
In the United States, new pharmaceutical products must be approved by the Food and Drug Administration (FDA) as being both safe and effective. This process generally involves submission of an Investigational New Drug filing with sufficient pre-clinical data to support proceeding with human trials. Following IND approva...
What type of filing is used before beginning risk assessment?
What type of filing is used before beginning risk assessment?
[ "What type of filing is used before beginning risk assessment?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29288
5ad39f27604f3c001a3fe943
Pharmaceutical_industry
In the United States, new pharmaceutical products must be approved by the Food and Drug Administration (FDA) as being both safe and effective. This process generally involves submission of an Investigational New Drug filing with sufficient pre-clinical data to support proceeding with human trials. Following IND approva...
How many phases of human trials may be done after review?
How many phases of human trials may be done after review?
[ "How many phases of human trials may be done after review?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29289
5ad39f27604f3c001a3fe944
Pharmaceutical_industry
In the United States, new pharmaceutical products must be approved by the Food and Drug Administration (FDA) as being both safe and effective. This process generally involves submission of an Investigational New Drug filing with sufficient pre-clinical data to support proceeding with human trials. Following IND approva...
What type of application is filed after completing three phases of products?
What type of application is filed after completing three phases of products?
[ "What type of application is filed after completing three phases of products?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29290
5ad39f27604f3c001a3fe945
Pharmaceutical_industry
In the United States, new pharmaceutical products must be approved by the Food and Drug Administration (FDA) as being both safe and effective. This process generally involves submission of an Investigational New Drug filing with sufficient pre-clinical data to support proceeding with human trials. Following IND approva...
What type of risk assessment results in approving the drug to go on to studies?
What type of risk assessment results in approving the drug to go on to studies?
[ "What type of risk assessment results in approving the drug to go on to studies?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29291
571d2f3bdd7acb1400e4c250
Pharmaceutical_industry
Advertising is common in healthcare journals as well as through more mainstream media routes. In some countries, notably the US, they are allowed to advertise directly to the general public. Pharmaceutical companies generally employ sales people (often called 'drug reps' or, an older term, 'detail men') to market direc...
"Drug reps" are usually hired by what type of firms?
"Drug reps" are usually hired by what type of firms?
[ "\"Drug reps\" are usually hired by what type of firms?" ]
{ "text": [ "Pharmaceutical companies" ], "answer_start": [ 191 ] }
gem-squad_v2-train-29292
571d2f3bdd7acb1400e4c251
Pharmaceutical_industry
Advertising is common in healthcare journals as well as through more mainstream media routes. In some countries, notably the US, they are allowed to advertise directly to the general public. Pharmaceutical companies generally employ sales people (often called 'drug reps' or, an older term, 'detail men') to market direc...
What law regulates drug marketing in the US?
What law regulates drug marketing in the US?
[ "What law regulates drug marketing in the US?" ]
{ "text": [ "Prescription Drug Marketing Act of 1987" ], "answer_start": [ 563 ] }
gem-squad_v2-train-29293
571d2f3bdd7acb1400e4c252
Pharmaceutical_industry
Advertising is common in healthcare journals as well as through more mainstream media routes. In some countries, notably the US, they are allowed to advertise directly to the general public. Pharmaceutical companies generally employ sales people (often called 'drug reps' or, an older term, 'detail men') to market direc...
Who do drug reps market to?
Who do drug reps market to?
[ "Who do drug reps market to?" ]
{ "text": [ "directly and personally to physicians" ], "answer_start": [ 315 ] }
gem-squad_v2-train-29294
5ad3a829604f3c001a3feae7
Pharmaceutical_industry
Advertising is common in healthcare journals as well as through more mainstream media routes. In some countries, notably the US, they are allowed to advertise directly to the general public. Pharmaceutical companies generally employ sales people (often called 'drug reps' or, an older term, 'detail men') to market direc...
"US reps" are usually hired by what type of firms?
"US reps" are usually hired by what type of firms?
[ "\"US reps\" are usually hired by what type of firms?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29295
5ad3a829604f3c001a3feae8
Pharmaceutical_industry
Advertising is common in healthcare journals as well as through more mainstream media routes. In some countries, notably the US, they are allowed to advertise directly to the general public. Pharmaceutical companies generally employ sales people (often called 'drug reps' or, an older term, 'detail men') to market direc...
What law regulates drug marketing in some countries?
What law regulates drug marketing in some countries?
[ "What law regulates drug marketing in some countries?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29296
5ad3a829604f3c001a3feae9
Pharmaceutical_industry
Advertising is common in healthcare journals as well as through more mainstream media routes. In some countries, notably the US, they are allowed to advertise directly to the general public. Pharmaceutical companies generally employ sales people (often called 'drug reps' or, an older term, 'detail men') to market direc...
Who do US reps market to?
Who do US reps market to?
[ "Who do US reps market to? " ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29297
5ad3a829604f3c001a3feaea
Pharmaceutical_industry
Advertising is common in healthcare journals as well as through more mainstream media routes. In some countries, notably the US, they are allowed to advertise directly to the general public. Pharmaceutical companies generally employ sales people (often called 'drug reps' or, an older term, 'detail men') to market direc...
Who do US companies generally employ?
Who do US companies generally employ?
[ "Who do US companies generally employ?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29298
5ad3a829604f3c001a3feaeb
Pharmaceutical_industry
Advertising is common in healthcare journals as well as through more mainstream media routes. In some countries, notably the US, they are allowed to advertise directly to the general public. Pharmaceutical companies generally employ sales people (often called 'drug reps' or, an older term, 'detail men') to market direc...
What is marketing of media in the US regulated by?
What is marketing of media in the US regulated by?
[ "What is marketing of media in the US regulated by?" ]
{ "text": [], "answer_start": [] }
gem-squad_v2-train-29299
571d34cadd7acb1400e4c256
Pharmaceutical_industry
There has been increasing controversy surrounding pharmaceutical marketing and influence. There have been accusations and findings of influence on doctors and other health professionals through drug reps, including the constant provision of marketing 'gifts' and biased information to health professionals; highly preval...
Drug reps have been accused of giving what to health professionals?
Drug reps have been accused of giving what to health professionals?
[ "Drug reps have been accused of giving what to health professionals?" ]
{ "text": [ "'gifts' and biased information" ], "answer_start": [ 251 ] }