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id stringlengths 40 40	title stringlengths 15 120	text stringlengths 41 3.14k	source stringclasses 2 values
c3c00bca634ce630f353e3347087382359c09cd6	the pathway for adenosine-phosphate deaminase involves two substrates,	the pathway for adenosine-phosphate deaminase involves two substrates, 5'-adenosine monophosphate and water. this pathway is referred to as amidine hydrolysis. adenosine-phosphate deaminase binds to 5'-amp using water to break the c-n bond and replacing it with a carbonyl group. ultimately, this produces 5'-imp (inosin...	wikipedia
abe7eb851799e1d0072b6d5619eded536d159b4d	the ec number for adenosine-phosphate deaminase is. the	the ec number for adenosine-phosphate deaminase is. the class is (ec 3) for hydrolase. hydrolases are enzymes that catalyze bond cleavage by reaction with water. the sub-class refers to adenosine-phosphate deaminase acting on carbon-nitrogen bonds, other than peptide bonds. the sub-sub-class refers to the type of subst...	wikipedia
f3f66321f336e4db1c19d19f35d120311f3f40b8	this enzyme belongs to the family of hydrolases,	this enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. the systematic name of this enzyme class is adenosine-phosphate aminohydrolase. other names in common use include adenylate deaminase, adenine nucleotide deaminase, and adeno...	wikipedia
bf04156492a79582591832d2606f714ccb7b46fe	on 1 june 1928 when aged 31, he	on 1 june 1928 when aged 31, he was interviewed by the board of directors from which he was announced as starting immediately as the first secretary manager of the dumfries club, queen of the south. he filled three roles at the club as he also signed himself as a player. in his first season, he was sent off when playin...	wikipedia
6082bf9fe9f092ed054d46d9dd34f72fbf745965	wright joined heart of midlothian for an estimated	wright joined heart of midlothian for an estimated fee of £2500 in 1922 – a record fee for an aberdeen player at the time – and remained a prominent figure in scottish football. for three successive seasons, he played in the annual east v west trial for the scotland national team. wright spent five seasons with hearts.	wikipedia
27d206d2c64da3a1b79f0b8f822742ef9e074f39	wright began playing with aberdeen when he was	wright began playing with aberdeen when he was only 16. he remained at the dons until 1922, captaining the side in his latter years at the club. he was regarded as one of the best half backs in scotland and gained representative honours when he played for the scottish league against the english league. he made 143 appe...	wikipedia
e97f26219d27aa7479e2bb64e18eb2bea5b6e3e7	the 2022–23 season was the 72nd season in	the 2022–23 season was the 72nd season in the history of ferencvárosi tc and their 6th consecutive season in the top flight. the club will participate in nemzeti bajnokság i, magyar kupa and the ehf european league.	wikipedia
e97f26219d27aa7479e2bb64e18eb2bea5b6e3e7	the 2022–23 season was the 72nd season in	the 2022–23 season was the 72nd season in the history of ferencvárosi tc and their 6th consecutive season in the top flight. the club will participate in nemzeti bajnokság i, magyar kupa and the ehf european league.	wikipedia
657c2a8641e756912a4e6b3e91974b7d6592b528	antonio lanzavecchia is an italian and swiss immunologist.	antonio lanzavecchia is an italian and swiss immunologist. as a fellow of collegio borromeo he obtained a degree with honors in medicine in 1976 from the university of pavia where he specialized in pediatrics and infectious diseases. he is head human immunology program, istituto nazionale di genetica molecolare-ingm, m...	wikipedia
4767ff41f0abe9aaa6b05505a0c5da880c6682be	in 2021, lanzavecchia and colleagues developed a vaccine	in 2021, lanzavecchia and colleagues developed a vaccine that protects animals from salmonella. recent highly cited work on covid-19 analyzes the sensitivity of the virus to mrna vaccine-elicited antibodies and the receptor-binding domain of the sars-cov-2 omicron variant.	wikipedia
9c47108c1f37e9c692ba14d01e61893482ef9641	the laboratory also pioneered the use of human	the laboratory also pioneered the use of human monoclonal antibodies as tools for vaccine design, a process dubbed as “analytic vaccinology” (,). basic studies addressed the role of somatic mutations in the development of broadly neutralizing antibodies () and the relationship between infection and autoimmunity (). the...	wikipedia
f4a48abc5be4b3f2afd5daf4b38b515182391a17	starting in 2003, the laboratory developed efficient methods	starting in 2003, the laboratory developed efficient methods to isolate human monoclonal antibodies as new tools for prophylaxis and therapy of infectious diseases (). among these is fi6 that neutralizes all influenza a viruses (), mpe8 that neutralizes four different paramyxoviruses () and mab114 (ansuvimab) that has ...	wikipedia
5e1f213abd126299b634848fbd8714ec6c0f92ad	in the late nineties the lanzavecchia laboratory determined	in the late nineties the lanzavecchia laboratory determined the mechanism, stoichiometry and kinetics of t cell receptor stimulation and signaling (,) and discovered a fundamental division of memory t cells into two major subsets of central memory and effector memory and central t cells that play distinct roles in imme...	wikipedia
47068faa83be6543ece1dcc4dd37d72a9c700f35	in 1994 sallusto and lanzavecchia discovered that human	in 1994 sallusto and lanzavecchia discovered that human monocytes could be induced to differentiate in vitro into immature dendritic cells that resemble those that function as sentinels in peripheral tissues (), contributing to the rapid advancement of the field in the late nineties. taking advantage of such immature d...	wikipedia
c40af91df2606dc369e737a95001538fa96586d4	starting in the early eighties, lanzavecchia has contributed	starting in the early eighties, lanzavecchia has contributed to the advancement of human immunology in three distinct fields: i) antigen presentation and dendritic cell biology; ii) lymphocyte activation and immunological memory and iii) human monoclonal antibodies. in 1985, using antigen-specific t and b cell clones, ...	wikipedia
514d732c9074421707f2f12546889fc2fb458f00	since 1980 lanzavecchia's laboratory developed robust methods to	since 1980 lanzavecchia's laboratory developed robust methods to study human t and b cells in vitro, first at the university of genoa, then at the basel institute for immunology and, from 1999 to 2020 at the institute for research in biomedicine in bellinzona, of which he was the founding director. he has been teaching...	wikipedia
f0d17293de98c73e3b728b50546b45c6936a265e	antonio lanzavecchia (born in varese october 9, 1951)	antonio lanzavecchia (born in varese october 9, 1951) is an italian and swiss immunologist. as a fellow of collegio borromeo he obtained a degree with honors in medicine in 1976 from the university of pavia where he specialized in pediatrics and infectious diseases. he is head human immunology program, istituto naziona...	wikipedia
b2e275ea467867aebc3fd4f62a949b0e5553dc79	gbadebo was ordained as assistant pastor of the	gbadebo was ordained as assistant pastor of the redeemed christian church of god in 2006 and ordained as a full pastor in 2009 during the convention theme "hope of glory". he is the country co-ordinator of the church in thailand.	wikipedia
e861966819f821ce3775fcbcda0f14ecfc195f45	gbadebo is an "a" license coach (by afc)	gbadebo is an "a" license coach (by afc) is currently coaching suphanburi f.c. in thai league 1. he was head coach for bangkok christian international school senior and under 15 soccer teams from 2007 to 2009 at tisac championship, assistant coach for thai port fc in the thailand f.a. cup champion in 2010, technical di...	wikipedia
203be327599898bc7214f6e1ac4976a38f2bcbdd	in 1993, gbadebo joined stationery stores f.c. during	in 1993, gbadebo joined stationery stores f.c. during 1990–1993, gbadebo was called to play for nigeria under-20 and under-23 national teams, from 1994 to 1998 he played for al-bourj fc and in 1998 moved to bec tero sasana the following year, he went on loan to mohun bagan ac, then back again to thailand to lead bec te...	wikipedia
e09c6c93032cdda472edb04b4f80804d481036fb	gbadebo attended ansar ud seen primary school odunfa	gbadebo attended ansar ud seen primary school odunfa at ebute metta in lagos state and ansar ud been grammar school at randle avenue surulere, lagos state, for his secondary school certificate. he also attended anwar ul islam college agege, lagos state, for his advanced level school certificate. he attended the univers...	wikipedia
77d5515ca3d1e04f9ee4dc835d25984e8419ee84	in enzymology, an agmatinase is an enzyme that	in enzymology, an agmatinase is an enzyme that catalyzes the chemical reaction thus, the two substrates of this enzyme are agmatine and h2o, whereas its two products are putrescine and urea. this enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in ...	wikipedia
a4ea9064666cbb51f1dd729ea72e916b84e775e1	as of late 2007, 5 structures have been	as of late 2007, 5 structures have been solved for this class of enzymes, with pdb accession codes 1gq6, 1gq7, 1wog, 1woh, and 1woi.	wikipedia
d5b7082253b86dc4bee253e14e22d6f764e1a60d	this enzyme belongs to the family of hydrolases,	this enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. the systematic name of this enzyme class is agmatine amidinohydrolase. other names in common use include agmatine ureohydrolase, and speb. this enzyme participates in urea cy...	wikipedia
6a117bd76bf1d3add10904804b76a22c5fb0ad23	3671 dionysus is a small binary amor asteroid,	3671 dionysus is a small binary amor asteroid, orbiting between earth and the asteroid belt. it was discovered by carolyn and gene shoemaker at palomar observatory on 27 may 1984. it is named after dionysus, the greek god of wine. its provisional designation was 1984 kd. it is an outer earth grazer because its periheli...	wikipedia
9c9d2ca28ce840e03ff640252cb51eedf1c7a5bd	in 1997, a team of astronomers at the	in 1997, a team of astronomers at the european southern observatory announced that lightcurve observations indicate the presence of a small moon orbiting dionysus. its provisional designation is s/1997 (3671) 1. this moon measures 300 meters in diameter, and orbits 3.6 km from dionysus with an eccentricity of 0.07 and ...	wikipedia
7dc8cbfbf391ae0d033722ee10d9f0cbd76677ff	dionysus makes modestly close approaches to earth. on	dionysus makes modestly close approaches to earth. on 19 june 1984 dionysus passed 0.0305 au (4,560,000 km; 2,840,000 mi) from earth. on 18 june 2085 it will pass 0.028 au (4,200,000 km; 2,600,000 mi) from earth.	wikipedia
53e62f74ec0e99c748e362df6e6c69b4a9d4bbed	3671 dionysus is a potentially hazardous asteroid (pha)	3671 dionysus is a potentially hazardous asteroid (pha) because its minimum orbit intersection distance (moid) is less than 0.05 au and its diameter is greater than 150 meters. the earth-moid is 0.01989 au (2,976,000 km; 1,849,000 mi). its orbit is well-determined for the next several hundred years.	wikipedia
6a117bd76bf1d3add10904804b76a22c5fb0ad23	3671 dionysus is a small binary amor asteroid,	3671 dionysus is a small binary amor asteroid, orbiting between earth and the asteroid belt. it was discovered by carolyn and gene shoemaker at palomar observatory on 27 may 1984. it is named after dionysus, the greek god of wine. its provisional designation was 1984 kd. it is an outer earth grazer because its periheli...	wikipedia
519ee9e5582bb964307ae683b56b2e8187e14177	"ai no tane" is the unofficial debut single	"ai no tane" is the unofficial debut single of japanese pop idol group morning musume, released under a defunct up-front group-affiliated independent label on november 3, 1997. it is sometimes called the "zeroth single"—"morning coffee" (モーニングコーヒー) being the "first single" and so on. it was later included in many other...	wikipedia
58d9415c19f03406151e8402103750aa823edcbe	the single was released and first distributed on	the single was released and first distributed on november 3 at shinsaibashi, osaka, selling 16,610 copies, and then on november 9 at fukuoka with 9,004 copies. distribution continued on november 23 at sapporo with 14,853 copies. during this event, kaori iida was hospitalized because her contact lens broke and caused te...	wikipedia
6e0ab1482f5b780a0c2d7c3fb4b057e880747ecc	recordings began on mid-september as well as the	recordings began on mid-september as well as the photoshoot for the cd cover. during the production, the group faced a big issue regarding with yuko nakazawa. at the beginning, nakazawa wore long hair that was originally featured in their single's cover. she later cut it short before debuting publicly. this act caused ...	wikipedia
42ed49b82be8aef629eedaf51977d189f4d4c1cb	in 1997, sharan q organized a talent search	in 1997, sharan q organized a talent search competition named "josei rokku vōkarisuto Ōdishon" (女性ロックヴォーカリストオーディション) under the show asayan. after the competition, producer and sharan q vocalist tsunku offered yuko nakazawa, aya ishiguro, kaori iida, natsumi abe, and asuka fukuda — five of the ten losers of the competit...	wikipedia
f4579675a3a05dcc880393b08ced53a765e773ba	it was later included in many other morning	it was later included in many other morning musume releases: in their first official single "morning coffee"; their first album, first time (ファーストタイム); and their first "best of" compilation, best! morning musume 1. an instrumental for this song was included in the bonus karaoke disc in the early single box.	wikipedia
4a0af365723747417caeabf9c3d185502265e2c8	" ai no tane " (愛の種, the seeds	" ai no tane " (愛の種, the seeds of love) is the unofficial debut single of japanese pop idol group morning musume, released under a defunct up-front group -affiliated independent label on november 3, 1997. it is sometimes called the "zeroth single" — " morning coffee " (モーニングコーヒー) being the "first single" and so on.	wikipedia
9904de2217e172887d1aca032383fe5408d05187	andrás cser is a hungarian linguist and professor	andrás cser is a hungarian linguist and professor of theoretical linguistics at pázmány péter catholic university. he is the editor-in-chief of acta linguistica academica.cser is known for his works on phonology.	wikipedia
913301062695b3a40d40b7cf9238f69af1dfe25a	the anderson impurity model, named after philip warren	the anderson impurity model, named after philip warren anderson, is a hamiltonian that is used to describe magnetic impurities embedded in metals. it is often applied to the description of kondo effect-type problems, such as heavy fermion systems and kondo insulators. in its simplest form, the model contains a term des...	wikipedia
78d6ea713eae4b9db359fc00a0db31d04b4e6ae0	there are other variants of the anderson model,	there are other variants of the anderson model, such as the su(4) anderson model, which is used to describe impurities which have an orbital, as well as a spin, degree of freedom. this is relevant in carbon nanotube quantum dot systems. the su(4) anderson model hamiltonian is	wikipedia
712ed2d69584ddbbe5b894a00981af8255b6a71e	where x j {\displaystyle x_{j}} is the position	where x j {\displaystyle x_{j}} is the position of impurity site j {\displaystyle j}, and f {\displaystyle f} is the impurity creation operator (used instead of d {\displaystyle d} by convention for heavy-fermion systems). the hybridization term allows f - orbital electrons in heavy fermion systems to interact, althoug...	wikipedia
bca5f0464ca6638111f920e25c1ff6c8d11bccf1	where the c {\displaystyle c} operator is the	where the c {\displaystyle c} operator is the annihilation operator of a conduction electron, and d {\displaystyle d} is the annihilation operator for the impurity, k {\displaystyle k} is the conduction electron wavevector, and σ {\displaystyle \sigma } labels the spin. the on–site coulomb repulsion is u {\displaystyle...	wikipedia