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ee0ae75683831a7ae274796f49b5a5b3082c1c78
1993–94 season was not a successful one. for
1993–94 season was not a successful one. for the first time in 8 years, beşiktaş finished the league outside of the top two while Özdilek had a quiet year comparing to his high standards and netted 8 goals. the sole consolation of the year was another turkish cup added to the club's trophy cabinet. next year saw the ar...
wikipedia
20f2ca1d8cba691181400316d1b3197694f991c8
in Özdilek's first year beşiktaş have won the
in Özdilek's first year beşiktaş have won the turkish cup and came second in the league. the following years proved to be even more successful for the team. under gordon milne 's helm, beşiktaş's young outfit started to dominate turkish football in a way which was unprecedented before. in the 1988–89 season beşiktaş cl...
wikipedia
81e0f84078b25fef2f4637e3c7126c005fa97ac5
born in samsun, Özdilek started to play at
born in samsun, Özdilek started to play at the amateur level with his hometown outfit samsun ladikspor. while he was only 16, he was scouted and picked up by kahramanmaraşspor, a team which has freshly promoted to the second-tier of turkish football. Özdilek managed to make an immediate impact on his new team and becam...
wikipedia
112903cca5befaf9120629045e2e9c7b3f64805d
for 13 years, beşiktaş has worn his form.
for 13 years, beşiktaş has worn his form. in 1991, he won the footballer of the year award in turkey. he took part in the squad which was the "undefeated champion" in 1992. with 130 goals it is the domestic midfielder who scored the most points of the süper lig in all time. he also scored 100 goals and entered the 100s...
wikipedia
dbf4a9350926d85813377d4affad0bb515e961b3
having spent most of his professional career with
having spent most of his professional career with beşiktaş, he is regarded as one of the idols of the İstanbul side. Özdilek is one of the most prolific scorers of turkish football despite playing mainly in midfield. during his beşiktaş days he has managed to score 130 goals which was a record for most goals scored by ...
wikipedia
73f231611d44296852f863d845ec069788ff36fa
mehmet " Şifo " Özdilek (born 1 april
mehmet " Şifo " Özdilek (born 1 april 1966, in samsun) is a turkish football manager and former player. he is nicknamed "Şifo" after belgian star enzo scifo with whom he shared a similar playing style.
wikipedia
60b9a8db013732e6c02f41c6af15fa77be10ab5a
in july 2018, bahn moved to hallescher fc.
in july 2018, bahn moved to hallescher fc. he made his competitive debut for the club on 28 july 2018 in a 2–0 away defeat to his former club, zwickau. he scored his first competitive goal for the club on 11 august 2018 in a 2–0 home victory over 1. fc kaiserslautern. his goal, scored in the 19th minute, came from the ...
wikipedia
e19546ece1b94c8b9f1dd81f1263cd941681f51f
in september 2017, bahn was signed by 3.
in september 2017, bahn was signed by 3. liga club fsv zwickau. he made his competitive debut for the club on 8 september 2017 in a 2–0 away victory over preußen münster. he scored his first competitive goal for the club on 23 september 2017 in a 1–0 home victory over werder bremen ii. he scored in the 86th minute.
wikipedia
4d004e816b39375b45e4b9e761dbc8ce4a71243e
in june 2016, bahn joined 3. liga club
in june 2016, bahn joined 3. liga club fsv frankfurt on a two-year contract, arriving alongside christopher schorch. he made his competitive debut for the club on 30 july 2016 in a 1–1 away draw with holstein kiel. he scored his first competitive goal for the club on 16 october 2016 in a 6–0 home victory over fortuna k...
wikipedia
356e714707c888e690aa2fc2f019deceaa5f560b
in january 2015 he joined 3. liga side
in january 2015 he joined 3. liga side stuttgarter kickers on a permanent basis, signing a contract until 2017. his previous club, fc st. pauli, though secured themselves a return option for summer 2016. he made his league debut for the club on 28 february 2015 in a 2–0 away victory over fortuna köln. he was subbed in ...
wikipedia
e2e0968ba4afbdea9a8fd52139836517c30e48e5
stephen michael gionta is an american former professional
stephen michael gionta is an american former professional ice hockey centre. he played in the national hockey league (nhl) with the new jersey devils and new york islanders. gionta is the younger brother of brian gionta, who played for the devils from 2001 to 2009.
wikipedia
aa29bb8a357b7a4c14580fcb47460fd675456cb3
on october 13, 2018, gionta returned to the
on october 13, 2018, gionta returned to the islanders, signing a one-year, two-way contract. he featured in five games with the islanders, going scoreless before he was assigned to play out the remainder of his contract in a return to the bridgeport sound tigers.
wikipedia
797288a1b55a79dff095768423efab6a133ce23c
after 11 seasons with the devils, gionta's association
after 11 seasons with the devils, gionta's association with the club ended as he was out of contract to become a free agent. unsigned over the following summer, gionta accepted a professional try-out contract to attend the new york islanders ' training camp on september 12, 2016. at the end of training camp, he signed ...
wikipedia
bc7a8e133b22e98955507a9bc86ff73ad8b68d02
on april 12, 2012, gionta scored his first
on april 12, 2012, gionta scored his first career nhl goal. the goal, which was the game-winning goal, was scored against craig anderson of the ottawa senators. the devils won the game 4–2, while gionta received first star honors of the game. during the 2012 postseason, gionta skated in 24 games with the devils, record...
wikipedia
cdb50c4ff2528b4cf1134764ae479d243b910ef7
after spending the next few seasons in the
after spending the next few seasons in the minor leagues, gionta was called up by the devils during the 2010-11 season. he made his debut on november 5, 2010 in a 3–0 loss to the new york rangers. gionta went scoreless in 12 games for the devils that season.
wikipedia
aeaacaf6634b3bea2b7035aaa8839b52875b47fa
gionta was not drafted by any team. however,
gionta was not drafted by any team. however, after graduating from boston college he signed an amateur tryout agreement with the albany river rats. the river rats were the american hockey league (ahl) affiliate of the new jersey devils, the team in which his older brother brian was a member of. gionta made his professi...
wikipedia
d81785fd7879b7ad7d7cbd4439f9bfe1e5a38e5d
stephen michael gionta (born october 9, 1983) is
stephen michael gionta (born october 9, 1983) is an american former professional ice hockey centre. he played in the national hockey league (nhl) with the new jersey devils and new york islanders. gionta is the younger brother of brian gionta, who played for the devils from 2001 to 2009.
wikipedia
6f6c33519c1209cfaf1ac9965581232d30ab380a
on 16 march 2016, zhangylyshbay signed a 1-year
on 16 march 2016, zhangylyshbay signed a 1-year contract, with the option of a second year, with fc aktobe. on 5 july 2016, zhangylyshbay left aktobe by mutual consent, signing for fc zhetysu the following day.
wikipedia
b6b760b145a1eb90f05069af8e88dfece79f9046
toktar sabituly zhangylyshbay (kazakh: Тоқтар Сәбитұлы Жанғылышбай; born
toktar sabituly zhangylyshbay (kazakh: Тоқтар Сәбитұлы Жанғылышбай; born 25 may 1993) is a kazakh footballer who plays as a forward for kaisar.
wikipedia
3d99b7403fc0525e4abbdbf07d6d4b1c9708a969
if a statistical procedure ordinarily compares distributions in
if a statistical procedure ordinarily compares distributions in terms of the determinants of variance-covariance matrices then, in the case of singular matrices, this comparison can be undertaken by using a combination of the ranks of the matrices and their pseudo-determinants, with the matrix of higher rank being coun...
wikipedia
1421a54f23f30f83a98e93d3e8a348423e7dc03d
supposing rank (a) = k {\displaystyle \operatorname {rank}
supposing rank (a) = k {\displaystyle \operatorname {rank} (a)=k}, so that k is the number of non-zero singular values, we may write a = p p † {\displaystyle a=pp^{\dagger }} where p {\displaystyle p} is some n -by- k matrix and the dagger is the conjugate transpose. the singular values of a {\displaystyle a} are the s...
wikipedia
a58c16537dffa46ce038c2c4073f9b7d1b0a7572
if a {\displaystyle a} is positive semi-definite, then
if a {\displaystyle a} is positive semi-definite, then the singular values and eigenvalues of a {\displaystyle a} coincide. in this case, if the singular value decomposition (svd) is available, then | a | + {\displaystyle |\mathbf {a} |_{+}} may be computed as the product of the non-zero singular values. if all singula...
wikipedia
14436590ed7c392e1411a4328a2d8982251256c5
if pdet > 0 {\displaystyle \operatorname {pdet} >0},
if pdet > 0 {\displaystyle \operatorname {pdet} >0}, the transformation is sense-preserving (rotation) whereas if the pdet < 0 {\displaystyle \operatorname {pdet} <0}, the transformation is sense-preserving (reflection).
wikipedia
44679e0878cd5b25d65545898120bbbf5daee96b
the vahlen matrix of a conformal transformation, the
the vahlen matrix of a conformal transformation, the möbius transformation (i.e. (a x + b) (c x + d) − 1 {\displaystyle (ax+b)(cx+d)^{-1}} for a, b, c, d ∈ g (p, q) {\displaystyle a,b,c,d\in {\mathcal {g}}(p,q)}), is defined as = {\displaystyle ={\begin{bmatrix}a&b\\c&d\end{bmatrix}}}. by the pseudo-determinant of the ...
wikipedia
cc409d1ceed8deb37e5168cd85133deb39fec081
the zlob trojan, identified by some antiviruses as
the zlob trojan, identified by some antiviruses as trojan.zlob, is a trojan horse which masquerades as a required video codec in the form of activex. it was first detected in late 2005, but only started gaining attention in mid-2006. once installed, it displays popup ads which appear similar to real microsoft windows w...
wikipedia
d4d48873aa0750bf88f0dcaf286a7471338fb97c
the group that created zlob has also created
the group that created zlob has also created a mac trojan with similar behaviors (named rsplug). some variants of the zlob family, like the so-called " dnschanger ", add rogue dns name servers to the registry of windows-based computers and attempt to hack into any detected router to change the dns settings, potentially...
wikipedia
1d3ee5d59cfbb3bcf020650cca4ca300b4ecec6a
project honeypot spam domains list (phsdl) tracks and
project honeypot spam domains list (phsdl) tracks and catalogs spam domains. some of the domains on the list are redirects to porn sites and various video watching sites that show a number of online videos. playing videos on these sites activates a request to download an activex codec which is malware. it prevents the ...
wikipedia
29585af73099ffc0e8268b01f420486be4c9d2be
the trojan has also been linked to downloading
the trojan has also been linked to downloading atnvrsinstall.exe which uses the windows security shield icon to look as if it is an anti-virus installation file from microsoft. having this file run can wreak havoc on computers and networks. one typical symptom is random computer shutdowns or reboots with random comment...
wikipedia
3618c8edad589f9e0c68191e4adc9dc66c08ade3
once installed, it displays popup ads which appear
once installed, it displays popup ads which appear similar to real microsoft windows warning popups, informing the user that their computer is infected with spyware. clicking these popups triggers the download of a fake anti-spyware program (such as virus heat and ms antivirus (antivirus 2009)) in which the trojan hors...
wikipedia
96f2c37c59d6bf02977888de4e7d6ec908e49454
the zlob trojan, identified by some antiviruses as
the zlob trojan, identified by some antiviruses as trojan.zlob, is a trojan horse which masquerades as a required video codec in the form of activex. it was first detected in late 2005, but only started gaining attention in mid-2006.
wikipedia
e0231cc663c3f3c68a21bd5d22e197c19fc8c943
microscopy is the technical field of using microscopes
microscopy is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye. there are three well-known branches of microscopy: optical, electron, and scanning probe microscopy, along with the emerging field of x-ray microscopy. optical microscopy and electron micr...
wikipedia
ef1963fd175e37f07d486f99f35ded961aa4ab83
this diversity of the types of microscopes in
this diversity of the types of microscopes in forensic applications comes mainly from their magnification ranges, which are (1- 1200x), (50 -30,000x) and (500- 250,000x) for the optical microscopy, sem and tem respectively.
wikipedia
bef8b185b71e2eb07c729ef5ac58503680ad7eb6
in the late 1800s, amateur microscopy became a
in the late 1800s, amateur microscopy became a popular hobby in the united states and europe. several 'professional amateurs' were being paid for their sampling trips and microscopic explorations by philanthropists, to keep them amused on the sunday afternoon (e.g., the diatom specialist a. grunow, being paid by (among...
wikipedia
1bfdc25c29d5b0c8726f1aeae031d298f4490143
while microscopy is a central tool in the
while microscopy is a central tool in the documentation of biological specimens, it is often insufficient to justify the description of a new species based on microscopic investigations alone. often genetic and biochemical tests are necessary to confirm the discovery of a new species. a laboratory and access to academi...
wikipedia
30d92856029abc6aab56294299fe75815b76ceb0
amateur microscopy is the investigation and observation of
amateur microscopy is the investigation and observation of biological and non-biological specimens for recreational purposes. collectors of minerals, insects, seashells, and plants may use microscopes as tools to uncover features that help them classify their collected items. other amateurs may be interested in observi...
wikipedia
e35b27fa46d9730e09ccccd876a4a42bcdf2f0b2
where λ {\displaystyle \lambda } is the wavelength
where λ {\displaystyle \lambda } is the wavelength of the excitation laser and na is the numerical aperture of the objective lens. the abbe diffraction limit holds if the incoming wave front is parallel. in reality, however, the laser beam profile is gaussian. therefore, in order to the calculate the achievable resolut...
wikipedia
8288613261c8076b66088e4cd873bcd651df8c6a
here Γ {\displaystyle \gamma } is the grüneisen
here Γ {\displaystyle \gamma } is the grüneisen coefficient, e l a s e r {\displaystyle e_{laser}} is the laser's photon energy and e g {\displaystyle e_{g}} is the sample's band gap energy. therefore, photoacoustic microscopy seems well suited as a complementary technique to fluorescence microscopy, as a high fluoresc...
wikipedia
a226d9ef4cdf3ae06db6e98550e3d8c5d3ebd93f
p a ∝ α ∗ Γ ∗ ((1
p a ∝ α ∗ Γ ∗ ((1 − η f l) ∗ e g + (e l a s e r − e g)) {\displaystyle pa\propto \alpha *\gamma *((1-\eta _{fl})*e_{g}+(e_{laser}-e_{g}))}
wikipedia
a5200e9f02463d40529b7ef69659d49a4f2ef576
the image contrast is related to the sample's
the image contrast is related to the sample's absorption coefficient α {\displaystyle \alpha }. this is in contrast to bright or dark field microscopy, where the image contrast is due to transmittance or scattering. in principle, the contrast of fluorescence microscopy is proportional to the sample's absorption too. ho...
wikipedia
bbedc20cc3fd4c5f8c8a9f41a62eb60edd34c290
a microscopy technique relying on the photoacoustic effect,
a microscopy technique relying on the photoacoustic effect, i.e. the generation of (ultra)sound caused by light absorption.a focused and intensity modulated laser beam is raster scanned over a sample. the generated (ultra)sound is detected via an ultrasound transducer. commonly piezoelectric ultrasound transducers are ...
wikipedia
3c78041fc6291a53a135a48826c08586d132ab22
high-intensity, short-pulse laboratory x-ray lasers have been under
high-intensity, short-pulse laboratory x-ray lasers have been under development for several years. when this technology comes to fruition, it will be possible to obtain magnified three-dimensional images of elementary biological structures in the living state at a precisely defined instant. for optimum contrast between...
wikipedia
be238ed7114775ee4a505116202fc6403c404299
laser microscopy is a rapidly growing field that
laser microscopy is a rapidly growing field that uses laser illumination sources in various forms of microscopy. for instance, laser microscopy focused on biological applications uses ultrashort pulse lasers, in a number of techniques labeled as nonlinear microscopy, saturation microscopy, and two-photon excitation mic...
wikipedia
af877cb45d616f66c8008cc6d02e9755d9a35132
digital pathology is an image-based information environment enabled
digital pathology is an image-based information environment enabled by computer technology that allows for the management of information generated from a digital slide. digital pathology is enabled in part by virtual microscopy, which is the practice of converting glass slides into digital slides that can be viewed, ma...
wikipedia
b7ed4764ccb229dc406c377e11a42c216c7c8ae0
a unique feature of dhm is the ability
a unique feature of dhm is the ability to adjust focus after the image is recorded, since all focus planes are recorded simultaneously by the hologram. this feature makes it possible to image moving particles in a volume or to rapidly scan a surface. another attractive feature is the ability of dhm to use low cost opti...
wikipedia
16d60ea2a4955276dc856b7c43ad62d5a7bd7389
dhm can operate both in reflection and transmission
dhm can operate both in reflection and transmission mode. in reflection mode, the phase shift image provides a relative distance measurement and thus represents a topography map of the reflecting surface. in transmission mode, the phase shift image provides a label-free quantitative measurement of the optical thickness...
wikipedia
4671d1e0e1d45df33a3f04849cd29d343f23ec87
in digital holographic microscopy (dhm), interfering wave fronts
in digital holographic microscopy (dhm), interfering wave fronts from a coherent (monochromatic) light-source are recorded on a sensor. the image is digitally reconstructed by a computer from the recorded hologram. besides the ordinary bright field image, a phase shift image is created.
wikipedia
8e5e863b168eb17dd6b3cd95573bee82a83fec74
ir versions of sub-diffraction microscopy also exist. these
ir versions of sub-diffraction microscopy also exist. these include ir near-field scanning optical microscope (nsom), photothermal microspectroscopy and atomic force microscope based infrared spectroscopy (afm-ir), as well as scattering-type scanning near-field optical microscopy (s-snom) & nano-ftir that provide nanos...
wikipedia
634baf1ea6eebe58b72117cb0f76b1f1e5f86100
the term infrared microscopy refers to microscopy performed
the term infrared microscopy refers to microscopy performed at infrared wavelengths. in the typical instrument configuration, a fourier transform infrared spectrometer (ftir) is combined with an optical microscope and an infrared detector. the infrared detector can be a single point detector, a linear array or a 2d foc...
wikipedia
bc494d929a41c3e1f64f2e0a3ece200892771f2c
ultraviolet microscopes have two main purposes. the first
ultraviolet microscopes have two main purposes. the first is to use the shorter wavelength of ultraviolet electromagnetic energy to improve the image resolution beyond that of the diffraction limit of standard optical microscopes. this technique is used for non-destructive inspection of devices with very small features...
wikipedia
e30da46bab6325f9aa110a843656f24a34fe2b73
ultrasonic force microscopy allows the local mapping of
ultrasonic force microscopy allows the local mapping of elasticity in atomic force microscopy by the application of ultrasonic vibration to the cantilever or sample. to analyze the results of ultrasonic force microscopy in a quantitative fashion, a force-distance curve measurement is done with ultrasonic vibration appl...
wikipedia
1f8343f9184c5c585901b6f8e5f452acb350b66d
ultrasonic force microscopy (ufm) has been developed in
ultrasonic force microscopy (ufm) has been developed in order to improve the details and image contrast on "flat" areas of interest where afm images are limited in contrast. the combination of afm-ufm allows a near field acoustic microscopic image to be generated. the afm tip is used to detect the ultrasonic waves and ...
wikipedia
77da4445eb3b091ad8554a3f55adbcd5460b0687
this is a sub-diffraction technique. examples of scanning
this is a sub-diffraction technique. examples of scanning probe microscopes are the atomic force microscope (afm), the scanning tunneling microscope, the photonic force microscope and the recurrence tracking microscope. all such methods use the physical contact of a solid probe tip to scan the surface of an object, whi...
wikipedia
33b4ea6c99e8111b864bc23e245ea2e610219d7b
until the invention of sub-diffraction microscopy, the wavelength
until the invention of sub-diffraction microscopy, the wavelength of the light limited the resolution of traditional microscopy to around 0.2 micrometers. in order to gain higher resolution, the use of an electron beam with a far smaller wavelength is used in electron microscopes.
wikipedia
6047f3900ea8b94da362072fb4771c504743113d
the creation of accurate micrographs requires a microscopical
the creation of accurate micrographs requires a microscopical technique using a monocular eyepiece. it is essential that both eyes are open and that the eye that is not observing down the microscope is instead concentrated on a sheet of paper on the bench besides the microscope. with practice, and without moving the he...
wikipedia
58b0f17a51f6ed87178e85c1318120d2be5b5141
most modern instruments provide simple solutions for micro-photography
most modern instruments provide simple solutions for micro-photography and image recording electronically. however such capabilities are not always present and the more experienced microscopist may prefer a hand drawn image to a photograph. this is because a microscopist with knowledge of the subject can accurately con...
wikipedia
9a9e706aedf19f16cea171a4bd983dbf59b7ed40
serial time encoded amplified microscopy (steam) is an
serial time encoded amplified microscopy (steam) is an imaging method that provides ultrafast shutter speed and frame rate, by using optical image amplification to circumvent the fundamental trade-off between sensitivity and speed, and a single-pixel photodetector to eliminate the need for a detector array and readout ...
wikipedia
199e1caff811e2194fa69423247241afaf2a1f03
this is mostly achieved by imaging a sufficiently
this is mostly achieved by imaging a sufficiently static sample multiple times and either modifying the excitation light or observing stochastic changes in the image. the deconvolution methods described in the previous section, which removes the psf induced blur and assigns a mathematically 'correct' origin of light, a...
wikipedia
56f100b1c8730b6c66d359fee23e226f1aa6b425
where n is the additive noise. knowing this
where n is the additive noise. knowing this point spread function means that it is possible to reverse this process to a certain extent by computer-based methods commonly known as deconvolution microscopy. there are various algorithms available for 2d or 3d deconvolution. they can be roughly classified in nonrestorativ...
wikipedia
d636ea2d8d1897b0d74231959d020eaf6d159d16
however, blurring is not caused by random processes,
however, blurring is not caused by random processes, such as light scattering, but can be well defined by the optical properties of the image formation in the microscope imaging system. if one considers a small fluorescent light source (essentially a bright spot), light coming from this spot spreads out further from ou...
wikipedia
80cc2b2e38972a295861ba5c50cf6b6dca6df302
fluorescence microscopy is a powerful technique to show
fluorescence microscopy is a powerful technique to show specifically labeled structures within a complex environment and to provide three-dimensional information of biological structures. however, this information is blurred by the fact that, upon illumination, all fluorescently labeled structures emit light, irrespect...
wikipedia
cad55d82d216d1ddcb93a3a0a436d9d513307244
wide-field multiphoton microscopy refers to an optical non-linear
wide-field multiphoton microscopy refers to an optical non-linear imaging technique in which a large area of the object is illuminated and imaged without the need for scanning. high intensities are required to induce non-linear optical processes such as two-photon fluorescence or second harmonic generation. in scanning...
wikipedia
cf4e6cce740d735daa7eb9c4a720c3398b651627
using a plane of light formed by focusing
using a plane of light formed by focusing light through a cylindrical lens at a narrow angle or by scanning a line of light in a plane perpendicular to the axis of objective, high resolution optical sections can be taken. single plane illumination, or light sheet illumination, is also accomplished using beam shaping te...
wikipedia
f351bbd113ad06d4ac033ef40d264f5c60a312ee
a two-photon microscope is also a laser-scanning microscope,
a two-photon microscope is also a laser-scanning microscope, but instead of uv, blue or green laser light, a pulsed infrared laser is used for excitation. only in the tiny focus of the laser is the intensity high enough to generate fluorescence by two-photon excitation, which means that no out-of-focus fluorescence is ...
wikipedia
d664e5b412fa6af492643c7b0bd582bbc098818c
a subclass of confocal microscopes are spinning disc
a subclass of confocal microscopes are spinning disc microscopes which are able to scan multiple points simultaneously across the sample. a corresponding disc with pinholes rejects out-of-focus light. the light detector in a spinning disc microscope is a digital camera, typically em-ccd or scmos.
wikipedia
320cc34784b4bd180987b2170d519446f8d0f08e
confocal laser scanning microscopy uses a focused laser
confocal laser scanning microscopy uses a focused laser beam (e.g. 488 nm) that is scanned across the sample to excite fluorescence in a point-by-point fashion. the emitted light is directed through a pinhole to prevent out-of-focus light from reaching the detector, typically a photomultiplier tube. the image is constr...
wikipedia
62b9ee17103fd4e8fd7e3789e64a097e4cdc2c56
to block the excitation light from reaching the
to block the excitation light from reaching the observer or the detector, filter sets of high quality are needed. these typically consist of an excitation filter selecting the range of excitation wavelengths, a dichroic mirror, and an emission filter blocking the excitation light. most fluorescence microscopes are oper...
wikipedia
96f9d0054843f0ee24eaf893cf8905181235fb46
since fluorescence emission differs in wavelength (color) from
since fluorescence emission differs in wavelength (color) from the excitation light, an ideal fluorescent image shows only the structure of interest that was labeled with the fluorescent dye. this high specificity led to the widespread use of fluorescence light microscopy in biomedical research. different fluorescent d...
wikipedia
f79e17d077c7dd39495f803120deb4cf703a9c23
growth of protein crystals results in both protein
growth of protein crystals results in both protein and salt crystals. both are colorless and microscopic. recovery of the protein crystals requires imaging which can be done by the intrinsic fluorescence of the protein or by using transmission microscopy. both methods require an ultraviolet microscope as proteins absor...
wikipedia
86e31c586f3d757b456a3d563652be0383f96cd6
highly efficient fluorescent proteins such as the green
highly efficient fluorescent proteins such as the green fluorescent protein (gfp) have been developed using the molecular biology technique of gene fusion, a process that links the expression of the fluorescent compound to that of the target protein. this combined fluorescent protein is, in general, non-toxic to the or...
wikipedia
d30fd501950b3b997186635730c061f5d68de079
the antibodies can be tailor-made for a chemical
the antibodies can be tailor-made for a chemical compound. for example, one strategy often in use is the artificial production of proteins, based on the genetic code (dna). these proteins can then be used to immunize rabbits, forming antibodies which bind to the protein. the antibodies are then coupled chemically to a ...
wikipedia
a7d903acac2e3d1469799d71a4de2c96aec2e0fb
this method is of critical importance in the
this method is of critical importance in the modern life sciences, as it can be extremely sensitive, allowing the detection of single molecules. many fluorescent dyes can be used to stain structures or chemical compounds. one powerful method is the combination of antibodies coupled to a fluorophore as in immunostaining...
wikipedia
01e5f9ab3e9e06bc6d1d9f131bdfa9f52f063f6e
an additional technique using interference is interference reflection
an additional technique using interference is interference reflection microscopy (also known as reflected interference contrast, or ric). it relies on cell adhesion to the slide to produce an interference signal. if there is no cell attached to the glass, there will be no interference.
wikipedia
f2988009653d69525eb11346bdca5e00915d7754
note: in cases where the optical design of
note: in cases where the optical design of a microscope produces an appreciable lateral separation of the two beams we have the case of classical interference microscopy, which does not result in relief images, but can nevertheless be used for the quantitative determination of mass-thicknesses of microscopic objects.
wikipedia
e921dca30cbec52d3852575cd4ae991e2667d37c
in a homogeneous specimen, there is no difference
in a homogeneous specimen, there is no difference between the two beams, and no contrast is being generated. however, near a refractive boundary (say a nucleus within the cytoplasm), the difference between the ordinary and the extraordinary beam will generate a relief in the image. differential interference contrast re...
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the system consists of a special prism (nomarski
the system consists of a special prism (nomarski prism, wollaston prism) in the condenser that splits light in an ordinary and an extraordinary beam. the spatial difference between the two beams is minimal (less than the maximum resolution of the objective). after passage through the specimen, the beams are reunited by...
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eb5795bf0199de7df5f287cefe62da2e7d5893c3
superior and much more expensive is the use
superior and much more expensive is the use of interference contrast. differences in optical density will show up as differences in relief. a nucleus within a cell will actually show up as a globule in the most often used differential interference contrast system according to georges nomarski. however, it has to be kep...
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0cbd071c52febe497b18ca9b2996703850f79be1
more sophisticated techniques will show proportional differences in
more sophisticated techniques will show proportional differences in optical density. phase contrast is a widely used technique that shows differences in refractive index as difference in contrast. it was developed by the dutch physicist frits zernike in the 1930s (for which he was awarded the nobel prize in 1953). the ...
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dispersion staining is an optical technique that results
dispersion staining is an optical technique that results in a colored image of a colorless object. this is an optical staining technique and requires no stains or dyes to produce a color effect. there are five different microscope configurations used in the broader technique of dispersion staining. they include brightf...
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rheinberg illumination is a variant of dark field
rheinberg illumination is a variant of dark field illumination in which transparent, colored filters are inserted just before the condenser so that light rays at high aperture are differently colored than those at low aperture (i.e., the background to the specimen may be blue while the object appears self-luminous red)...
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a88f35cfeb3edbd584aadbbbeac2bad4ed6c615b
dark field microscopy is a technique for improving
dark field microscopy is a technique for improving the contrast of unstained, transparent specimens. dark field illumination uses a carefully aligned light source to minimize the quantity of directly transmitted (unscattered) light entering the image plane, collecting only the light scattered by the sample. dark field ...
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c2ac30824cbb6fe28aca93612091e88af0d97cb1
the use of oblique (from the side) illumination
the use of oblique (from the side) illumination gives the image a three-dimensional appearance and can highlight otherwise invisible features. a more recent technique based on this method is hoffmann's modulation contrast, a system found on inverted microscopes for use in cell culture. oblique illumination enhances con...
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6304f1d9fbb226dc9e43226fd217758fb16a8915
bright field microscopy is the simplest of all
bright field microscopy is the simplest of all the light microscopy techniques. sample illumination is via transmitted white light, i.e. illuminated from below and observed from above. limitations include low contrast of most biological samples and low apparent resolution due to the blur of out-of-focus material. the s...
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37d388d4b3ee87bbc9a6b1a3dedfa33eb4ba2ef4
live cells in particular generally lack sufficient contrast
live cells in particular generally lack sufficient contrast to be studied successfully, since the internal structures of the cell are colorless and transparent. the most common way to increase contrast is to stain the structures with selective dyes, but this often involves killing and fixing the sample. staining may al...
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24a912d51857365d11a2e270a3556f492d63382a
optical or light microscopy involves passing visible light
optical or light microscopy involves passing visible light transmitted through or reflected from the sample through a single lens or multiple lenses to allow a magnified view of the sample. the resulting image can be detected directly by the eye, imaged on a photographic plate, or captured digitally. the single lens wi...
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875a43a52fbf648461ca7685fe82c3ae0c14a847
the field of microscopy (optical microscopy) dates back
the field of microscopy (optical microscopy) dates back to at least the 17th-century. earlier microscopes, single lens magnifying glasses with limited magnification, date at least as far back as the wide spread use of lenses in eyeglasses in the 13th century but more advanced compound microscopes first appeared in euro...
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optical microscopy and electron microscopy involve the diffraction,
optical microscopy and electron microscopy involve the diffraction, reflection, or refraction of electromagnetic radiation /electron beams interacting with the specimen, and the collection of the scattered radiation or another signal in order to create an image. this process may be carried out by wide-field irradiation...
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fdb109a1da0968a7b01d552c29042f060a154446
microscopy is the technical field of using microscopes
microscopy is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye (objects that are not within the resolution range of the normal eye). there are three well-known branches of microscopy: optical, electron, and scanning probe microscopy, along with the eme...
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72f2d7bfb017816d64e301a3390efca101f93c9e
professor victor on-kwok li is an american hong
professor victor on-kwok li is an american hong kong academic. he is best known for his contributions to the development of information technology. he received the government of hong kong bronze bauhinia star in 2001, and he is a fellow of institute of electrical and electronics engineers. prof. li is currently chair p...
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e995c2c7a1f22048e2cf84fe2cccd10ad476e900
from 2007 to 2012, he served as associate
from 2007 to 2012, he served as associate dean of engineering at hku. before joining hku in 1997, he was a professor of electrical engineering (ee) at the university of southern california (usc) and director of communication sciences institute of usc. he chaired the computer communications technical committee of the ie...
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3e5bbcb05ec150fc62ee6bfc2747bd5c7f596daa
prof. li is currently chair professor and head
prof. li is currently chair professor and head of the department of electrical and electronic engineering of the university of hong kong (hku). he also serves as managing director of versitech ltd. he is also on the boards of sunevision ltd., china.com ltd., and anxin-china holding ltd. prof. li also chairs the executi...
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babb6f078070866b373f41cf272b654183c20e50
professor victor on-kwok li (born october 11, 1954)
professor victor on-kwok li (born october 11, 1954) is an american hong kong academic. he is best known for his contributions to the development of information technology. he received the government of hong kong bronze bauhinia star in 2001, and he is a fellow of institute of electrical and electronics engineers.
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8acdfe44340a49fbc946216d0accc97fc9b56e37
actaea, officially (120347) salacia i actaea, is a
actaea, officially (120347) salacia i actaea, is a natural satellite of the classical kuiper belt object 120347 salacia. its diameter is estimated to be approximately 300 km (190 mi), which is approximately one-third the diameter of salacia; thus, salacia and actaea are viewed by william grundy et al. to be a binary sy...
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a64ddebd0d2c48063cf3020a0af32a0b5f2ff303
the mass of the system is (4.92 ±
the mass of the system is (4.92 ± 0.07) × 10 kg, with actaea constituting perhaps 4% of this. actaea is 2.372 ± 0.060 magnitudes fainter than salacia, implying a diameter ratio of 2.98 for equal albedos. hence, assuming equal albedos, it has a diameter of 284 ± 10 km. actaea has the same color as salacia (v−i = 0.89 ± ...
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94d302bb1ddf13ad969516a7282effab00582188
actaea orbits its primary every 5.493 d at
actaea orbits its primary every 5.493 d at a distance of 5619 ± 87 km and with an eccentricity of 0.0084 ± 0.0076. the ratio of its semi-major axis to its primary's hill radius is 0.0023, the tightest trans-neptunian binary with a known orbit.
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c084d050f00cb0d5d31d9974010eb09bd7fc7389
it was discovered on 21 july 2006 by
it was discovered on 21 july 2006 by keith s. noll, harold levison, denise stephens, and will grundy with the hubble space telescope. on 18 february 2011, it was officially named actaea after the nereid nymph named actaea.
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e4aa704f1e910b5c4d8878df74eba3002874edbb
actaea, officially (120347) salacia i actaea, is a
actaea, officially (120347) salacia i actaea, is a natural satellite of the classical kuiper belt object 120347 salacia. its diameter is estimated to be approximately 300 km (190 mi), which is approximately one-third the diameter of salacia; thus, salacia and actaea are viewed by william grundy et al. to be a binary sy...
wikipedia
27aa18a51684e9a2aa482ac76bad7b06843d57db
f. douglas bolstorff was an american basketball player
f. douglas bolstorff was an american basketball player and coach. he played collegiately for the university of minnesota. he was selected by the detroit pistons in the 8th round of the 1957 nba draft. he played for the pistons (1957–58) in the nba for three games. f. doug bolstorff also served as coach of macalester co...
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0529965940079b99e463ebcd5db238406ea8aa09
k. tsianina lomawaima is an american interdisciplinary researcher
k. tsianina lomawaima is an american interdisciplinary researcher of indigenous studies, anthropology, history, and political science. she is a professor in the school of social transformation at arizona state university. she specializes in the interaction between sovereign native nations and u.s. federalism, the statu...
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00b3be64224be48e44ccfe85c01e52649da78f0c
in 2007 lomawaima co-founded the native american and
in 2007 lomawaima co-founded the native american and indigenous studies association, and she served as its president in 2012–2013. lomawaima was the 2010 recipient of the lifetime achievement award for american indian history from the western history association. in 2016, she was named a member of the national academy ...
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afb61aa65a0476046c9e382e28e4d8fd31ab54cb
lomawaima has also coauthored multiple books. in 2000,
lomawaima has also coauthored multiple books. in 2000, she published away from home: american indian boarding school experiences with margaret archuleta and brenda child. in 2001, she and david e. wilkins published uneven ground: american indian sovereignty and federal law. uneven ground was selected as an outstanding ...
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