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b024e0a8035915948b58e55aaff4b605abd37226 | in mathematics, the cartan–hadamard conjecture is a fundamental | in mathematics, the cartan–hadamard conjecture is a fundamental problem in riemannian geometry and geometric measure theory which states that the classical isoperimetric inequality may be generalized to spaces of nonpositive sectional curvature, known as cartan–hadamard manifolds. the conjecture, which is named after f... | wikipedia |
ef0b520061c5a44a1d5bb4e527df45effdd56a2c | chajiaotan bridge is a suspension bridge in xishui | chajiaotan bridge is a suspension bridge in xishui county, guizhou, china. it is one of the highest bridges in the world at 323 m (1,060 ft). the bridge is part of the xugu expressway carrying traffic over the chishui river. construction began in 2014 and the bridge opened in 2020. the main span of the bridge is 1,200 ... | wikipedia |
2ccb0ce29bb1d07d25caa59b44938dd84be4a3be | chishuihe bridge chajiaotan is the last link along | chishuihe bridge chajiaotan is the last link along the 84-kilometre (52 mi) xugu expressway that connects the city of xuyong on the g76 with the city of gulin and eventually the chishui river gorge where it will connect with the renchi expressway in guizhou. construction was completed in 2016 on all but the very easter... | wikipedia |
abb615d0007b2b331b175138d9db740701bd3238 | chajiaotan bridge is a suspension bridge in xishui | chajiaotan bridge is a suspension bridge in xishui county, guizhou, china. it is one of the highest bridges in the world at 323 m (1,060 ft). the bridge is part of the xugu expressway carrying traffic over the chishui river. construction began in 2014 and the bridge opened in 2020. the main span of the bridge is 1,200 ... | wikipedia |
3fa72a5420c43953beb03d1dd57c8d37a535e0ca | an evolutionary landscape is a metaphor or a | an evolutionary landscape is a metaphor or a construct used to think about and visualize the processes of evolution acting on a biological entity. this entity can be viewed as searching or moving through a search space. for example, the search space of a gene would be all possible nucleotide sequences. the search space... | wikipedia |
9586d33bc0f5e1d26113661d6ac22a63c3b39995 | the second example comes from a paper titled | the second example comes from a paper titled "synonymous genes explore different evolutionary landscapes." the authors of this paper are broadly interested in the ability of a protein to evolve. they specifically wanted to know how synonymous substitutions affected the evolutionary landscape of a protein. to do this, t... | wikipedia |
4708a1e056655d4007f1d042e07e22677c53c19e | recent increases in computational power and ease of | recent increases in computational power and ease of sequencing have allowed the concept of evolutionary landscapes to be taken from a purely conceptual metaphor to something that can be modeled and explored. this is especially true of the field of genomics. one good example is the research article "the evolutionary lan... | wikipedia |
f70eab18a2a4e5ce9801ca50ee12227a4028e998 | recent increases in computational power and ease of | which started in asia and is still occurring in europe and africa. the second haplotype is restricted to europe and is not in linkage disequilibrium with the global haplotype. this european haplotype carries with it a mutation associated with autoimmune diseases. the authors hypothesize another mutation in the haploty... | wikipedia |
6aa4399f30d9e0a9d7ce3fafeaa93c66de73b0c7 | morphospaces also lack a dimension of fitness. instead, | morphospaces also lack a dimension of fitness. instead, their axes are mathematical models of phenotypic traits developed a priori to observational measurements. observational measurements are then mapped onto the resulting surface to indicate areas of possible phenotypic space occupied by the species under considerati... | wikipedia |
4647917170a6ad1ed2e7ba191df6a2ec91ac5963 | selection-weighted attraction graphing (swag) uses force-directed network graphing | selection-weighted attraction graphing (swag) uses force-directed network graphing to visualize fitness landscapes. in this visualization, genotypes are represented by nodes which are attracted to each other in proportion to the relative change in fitness between them (nodes will tend to be closer if there is stronger ... | wikipedia |
f250bc4de9ec7d9f66f5a116faa5886255378c70 | while kaplan (2008) wishes to discard the idea | while kaplan (2008) wishes to discard the idea of landscapes all together, massimo pigliucci is less drastic. he acknowledges four categories of landscapes: fitness landscapes, adaptive landscapes, fitness surfaces, and morphospaces. fitness landscapes are those similar to what wright (1932) proposed (called adaptive a... | wikipedia |
ce8eea0912f7097c189cd2921fbbc55b49bcba8f | the work of gavrilets, along with other issues, | the work of gavrilets, along with other issues, has prompted kaplan (2008) to propose abandoning the metaphor of evolutionary landscapes (which he calls adaptive or fitness landscapes). kaplan (2008) has six main criticisms of the metaphor: (1) it has no explanatory power; (2) it lacks a relevant mathematical model; (3... | wikipedia |
70483561deec893e7f6edd4c215de92290c78474 | one of the first criticisms (or at least | one of the first criticisms (or at least difficulty) with evolutionary landscapes is their dimensionality. wright recognized that true landscapes can have thousands of dimensions, but he also felt reducing those dimensions to two was acceptable since his point in doing so was simply to convey a complex idea. as a visua... | wikipedia |
f9b5246637979cd94631aa93418b143958af3111 | the concept of evolutionary landscapes changed once more | the concept of evolutionary landscapes changed once more as the modern understanding of molecular evolution emerged. it is claimed that maynard smith (1970) was the first to visualize protein evolution as a network of proteins one mutational step away from others. however, for this to be true, there must be pathways be... | wikipedia |
5c67fe28532688bb625d37b90d604cd847b7f70e | in a series of papers, russell lande developed | in a series of papers, russell lande developed a mathematical model for simpson's phenotypic landscape. lande reconciled wright's population-level view with simpson's use of higher taxonomic levels. lande considers fitness peaks to be determined by the environment and thus represent ecological niches or adaptive zones ... | wikipedia |
0f90ffc131966eaa7cf24e02bb8b3322c844f981 | in 1944, simpson expanded wright's landscape to include | in 1944, simpson expanded wright's landscape to include phenotypes. in simpson's model, the landscape is a means of visualizing the "relationship between selection, structure, and adaptation." unlike wright, simpson used the landscape to represent both natural selection and genetic drift. uphill movements are due to po... | wikipedia |
3a09ff5908432e4d5d0afea5c26c1b0f76d5dabd | credit for the first evolutionary landscape typically goes | credit for the first evolutionary landscape typically goes to sewall wright, and his idea has arguably had a much larger audience and greater influence on the field of evolutionary biology than any other comparable understanding of "evolutionary landscape". in his 1932 paper, wright presents the concept of an evolution... | wikipedia |
677a1725d960f141a47464e67f7a48ed9d113c75 | according to mccoy (1979), the first evolutionary landscape | according to mccoy (1979), the first evolutionary landscape was presented by armand janet of toulon, france, in 1895. in janet's evolutionary landscape, a species is represented as a point or an area on a polydimensional surface of phenotypes, which is reduced to two dimensions for simplicity. the size of the populatio... | wikipedia |
068909bc948afe20104a02d711eb7735cfa48ac5 | what exactly constitutes an "evolutionary landscape" is frequently | what exactly constitutes an "evolutionary landscape" is frequently confused in the literature; the term is often used interchangeably with "adaptive landscape" and "fitness landscape", although some authors have different definitions of adaptive and fitness landscapes. additionally, there is a large disagreement whethe... | wikipedia |
29e00dac290769d01bc126f371f3697ccc05aa5a | an evolutionary landscape is a metaphor or a | an evolutionary landscape is a metaphor or a construct used to think about and visualize the processes of evolution (e.g. natural selection and genetic drift) acting on a biological entity (e.g. a gene, protein, population, or species). this entity can be viewed as searching or moving through a search space. for exampl... | wikipedia |
72bd7807586947796b0daf5e0f0ef900d714e70d | by 5 february the territory had 7,372 active | by 5 february the territory had 7,372 active cases of covid. 867 new cases were reported, for 22,492 total since march 2020. 129 cases were hospitalised, with 28 in intensive care, 3 on oxygen. | wikipedia |
f3247e20c3344f75319d71ceeae31bbf565d2a25 | on 2 february nt had its fourth covid | on 2 february nt had its fourth covid related death, a man his 80s. he died at old timers aged care service in alice springs where he lived. he was not vaccinated and also had underlying health conditions. by that day the territory had 6,576 active cases of covid. 1,201 new cases were reported and 129 cases were hospit... | wikipedia |
1395bf4818feede98b7daf7bae17f5491f1877bf | on 31 january another covid related death occurred, | on 31 january another covid related death occurred, nts' third, at the alice springs hospital. the death was a woman from the remote aboriginal community of mutitjulu, near ayer's rock. she had received 1 dose of covid vaccine. | wikipedia |
91573b73adc2aa69647a112530f1f9d3bde7dd84 | on 16 january, at 3pm alice springs entered | on 16 january, at 3pm alice springs entered a 'lockout', wherein those not fully vaccinated must remain in isolation, under similar conditions to a general covid lockdown. outbreaks have occurred in alice springs and darwin prisons, aged care facilities and a renal hostel in alice springs. the restrictions are due to b... | wikipedia |
4bcdc6295d0d45765a8977b85beac6ed1363dd59 | by this day the territory had 3,730 active | by this day the territory had 3,730 active cases of covid, most in greater darwin. 412 new cases were reported to 8pm on 14 january, and 32 cases were hospitalised, with none in intensive care. | wikipedia |
dac414751533906dfa103597c3eb2144bcb73ddc | on 6 january, from 1pm, a lockout was | on 6 january, from 1pm, a lockout was implemented over the entire territory until mid-day on 9 january. a vaccine pass system came into effect at that time as well. everyone in the nt will have to show proof of their covid-19 vaccination status before being be allowed to enter venues such as casinos, cinemas, clubs, pu... | wikipedia |
4c7ffc2d5299d487d6a8ae0eb269faf87c3e4ff5 | on 1 december, lajamanu's lockdown was downgraded to | on 1 december, lajamanu's lockdown was downgraded to a lockout, and robinson river moved out of lockout. on 2 december, a positive case was recorded at lajamanu. binjari's hard lockdown was moved to a standard lockdown. | wikipedia |
25f8252b8f6ff805877fded3ff3d2834e2b5306e | on 29 november, a positive case of the | on 29 november, a positive case of the sars-cov-2 omicron variant was recorded at the howard springs quarantine facility, from a return traveller who arrived at darwin from johannesburg, south africa on 25 november. | wikipedia |
fe6fe4f1d6838eb3ab52d35de85f3267891798b7 | on 15 november, the nt recorded two new | on 15 november, the nt recorded two new cases, one in katherine and one in robinson river, northern territory, a remote community about 800 kilometres east of katherine. both greater katherine and robinson river and its surrounding homelands entered lockdown. the outbreak was later confirmed to be linked to the cluster... | wikipedia |
fdb6fec6a2d6a9b23707028f797e67ec2d294350 | on 4 november, the nt recorded its first | on 4 november, the nt recorded its first case of covid-19 community transmission, when a person who had spent time in katherine and greater darwin tested positive. as a result, katherine entered lockdown while the greater darwin region entered lockout. the primary infection case was traced to a person who "almost certa... | wikipedia |
7b9a9de377596cf30eea8feb3aa2062e2b90fa50 | on 16 august greater darwin and the katherine | on 16 august greater darwin and the katherine region went into another snap lockdown due to end at mid-day on 19 august. this followed one new covid case who was infectious in the community for several days. he was an international arrival, coming from the u.s. to australia and nt for legitimate work purposes, who had ... | wikipedia |
bf96fcfd79d49ef8ce637a877c1c03317a1408e6 | on 28 june, as the mine covid cluster | on 28 june, as the mine covid cluster in nt had grown to 7 cases, the lockdown in darwin was extended by 72 hours to 1pm on 2 july. the fireworks for territory day on 1 july were postponed. | wikipedia |
42516d7051c06939bf834ac9d0cd17bfa4c6736a | from 1pm on 27 june, darwin went into | from 1pm on 27 june, darwin went into a 'snap' lockdown, for at least 48 hours, after more covid-19 cases were confirmed that were linked to the granites gold mine case. they were believed to be of the delta covid-19 variant. the affected areas are the darwin, palmerston and litchfield council areas. during the lockdow... | wikipedia |
dfb111fa82a53ebc3ce0ee69c1ac9d8dd255d081 | on 26 june the granites gold mine went | on 26 june the granites gold mine went into lockdown after a worker tested positive for covid-19. the mine is 540 km (340 mi) north-west of alice springs. about 750 fifo (fly-in/fly-out) workers onsite were affected, while about 900 who left the site recently had to go into isolation, 259 in nt, but 650 went elsewhere ... | wikipedia |
ac47422ad32daf980711249f81bccf3b75f9d791 | due to a growing cluster in bondi, sydney, | due to a growing cluster in bondi, sydney, from 6pm (local) on 24 june, the northern territory declared all of greater sydney a hotspot. any person entering nt from sydney will have to quarantine for 14 days. | wikipedia |
7a1d1f1c2071c1820687950dcc618b4197ff2de9 | by 7 june more than 10,000 northern territorians | by 7 june more than 10,000 northern territorians had been fully vaccinated. the nt vaccination program was extended to anyone in darwin and palmerston over 16 years-of-age from 8 june. previously, those over 16 could usually only book for the vaccine if they lived in regional parts of the nt, such as alice springs and ... | wikipedia |
c8c64b93831ab92886d8efafe092a961613ce4f0 | on 3 february 2021, after a quarantine hotel | on 3 february 2021, after a quarantine hotel worker at the grand hyatt melbourne, involved in the australian open tennis quarantine program, was found to have covid-19, victoria reintroduced some rules, and delayed the imminent easing of some restrictions. on 4 february 2021 the northern territory responded to the melb... | wikipedia |
d64dfdbf9542f3b6cde37b0302b8def33251a2cb | on 24 march 2020, the northern territory (nt) | on 24 march 2020, the northern territory (nt) government introduced strict border control, with anyone arriving from abroad or interstate being required to self-isolate for 14 days. the only exemption would be due to health and emergency services, defence and policing, flight crews and freight, and based on "compassion... | wikipedia |
74f11a0e6e08d8d97684ed3d01613047c2464dbb | context-sensitive half-life or context sensitive half-time is defined | context-sensitive half-life or context sensitive half-time is defined as the time taken for blood plasma concentration of a drug to decline by one half after an infusion designed to maintain a steady state has been stopped. the "context" is the duration of infusion. when a drug which has a multicompartmental pharmacoki... | wikipedia |
f0aa5ed04d118e05911b481edb39bae12abc261f | when a drug which has a multicompartmental pharmacokinetic | when a drug which has a multicompartmental pharmacokinetic model is given by intravenous infusion it initially will distribute to the central compartment and then move out of this compartment into one or two peripheral compartments. once this infusion is discontinued, drug continues to move into the peripheral compartm... | wikipedia |
b9d592c3e01eb4c75b64537e48e25891a5576be6 | context-sensitive half-life or context sensitive half-time is defined | context-sensitive half-life or context sensitive half-time is defined as the time taken for blood plasma concentration of a drug to decline by one half after an infusion designed to maintain a steady state (i.e. a constant plasma concentration) has been stopped. the "context" is the duration of infusion. | wikipedia |
ae00f0b79a9761ac8f90e98da202dbbeae3c20ac | she was married twice: to the economic historian | she was married twice: to the economic historian a n "max" cole from whom she was divorced in 1960. from 1962 to 1968, she was married to bill wedderburn, baron wedderburn of charlton, a union that also ended in divorce. both marriages were childless. | wikipedia |
7c736ac5590c96c615f540e855daa78cf72060bb | wedderburn was a pro-vice-chancellor of the university of | wedderburn was a pro-vice-chancellor of the university of london from 1986 to 1988. from 1981 to 2003 she was also a senior research fellow at imperial college. she was honorary president of the fawcett society from 1986 to 2002. from 1998 to 2000, she was chair of the committee of enquiry into women in prison. | wikipedia |
b86e0443442e186cfdcdcd1eb84159483407b4d2 | between 1993 and 1995, a j. m. w. | between 1993 and 1995, a j. m. w. turner (van tromp going about to please his masters, ships at sea, getting a good wetting c. 1844), john constable (a sketch for view on the stour, nr dedham c.1821/2) and thomas gainsborough (peasants going to market: early morning c. 1770) were sold for a total of £21m. holloway's re... | wikipedia |
3bb24333faf82c1693a15cb45a507c8a91021efa | the late 1980s were difficult times financially for | the late 1980s were difficult times financially for universities including the new college. she closed the chemistry department, for which the extensive bourne building had been constructed in the late 1960s, as chemistry had become too expensive a subject. she reduced staff across all departments and, more controversi... | wikipedia |
0909831ab56c92f61aed064491eedc75a26b645a | the official title (royal holloway and bedford new | the official title (royal holloway and bedford new college) is still retained, but for everyday use the college is now referred to as royal holloway, university of london or simply royal holloway, london. on leaving royal holloway she declined the damehood normally offered to former female principals. there is no expla... | wikipedia |
87a0dfb6c7b18d5749940c86a140182b39b23cb1 | in 1981 she became principal of bedford college. | in 1981 she became principal of bedford college. the 1982 partnership agreement between bedford and royal holloway was signed as a result of severe cuts in government spending on higher education. discussions had taken place between wedderburn and holloway's then principal, dr lionel butler. before anything was finalis... | wikipedia |
8988b4fad375eae25df5a1b1e54eff439139c4b7 | she was a research officer at the board | she was a research officer at the board of trade from 1946 to 1966, did research in applied economics at cambridge and then worked as a lecturer, and subsequently reader and professor, in industrial sociology at the imperial college of science and technology in london, then part of the university of london, from 1965 t... | wikipedia |
e833d693bdaa44bfdf87bc2607afffcf74a7e6b6 | wedderburn was born in walthamstow and educated at | wedderburn was born in walthamstow and educated at walthamstow county high school for girls in north-east london and girton college, cambridge, where she read economics. she joined the communist party in the 1940s, but ended her membership of the party in the late 1950s, while remaining on the left of the labour moveme... | wikipedia |
48b50c41a9699d840ea79741e05f6d975e5e0e73 | dorothy enid wedderburn (née barnard, formerly cole; 18 | dorothy enid wedderburn (née barnard, formerly cole; 18 september 1925 – 20 september 2012) was principal of bedford college, part of the university of london, and after the merger with royal holloway college, another college of the university, was the first principal of the combined institution. | wikipedia |
d574e72565bf7baccc810dad6dfd9336f6438b84 | in electronics, an electronic switch is a switch | in electronics, an electronic switch is a switch controlled by an active electronic component or device. without using moving parts, they are called solid state switches, which distinguishes them from mechanical switches. electronic switches are considered binary devices because they dramatically change the conductivit... | wikipedia |
4fd3909060c83973de938e82bc3b138434005293 | the diode can be treated as switch that | the diode can be treated as switch that conducts significantly only when forward biased and is otherwise effectively disconnected (high impedance). specific diode types that can change switching state quickly, such as the schottky diode and the 1n4148, are called "switching diodes". | wikipedia |
acf45cf2d1c2540626721577121c2b60954c4ef9 | early telephone systems used an electromagnetically operated strowger | early telephone systems used an electromagnetically operated strowger switch to connect telephone callers; later telephone exchanges contain one or more electromechanical crossbar switches. thus the term 'switched' is applied to telecommunications networks, and signifies a network that is circuit switched, providing de... | wikipedia |
67ac1b6a778ff21b44c2f85e3bcc70a34736d0d9 | the traditional relay is an electromechanical switch that | the traditional relay is an electromechanical switch that uses an electromagnet controlled by a current to operate a mechanical switching mechanism. other operating principles are also used (for instance, solid-state relays invented in 1971 control power circuits with no moving parts, instead using a semiconductor devi... | wikipedia |
3cead5556a39bec8d9db870d478968ecbc64355a | diadenylate cyclase ec 2.7.7.85, dna integrity scanning protein | diadenylate cyclase ec 2.7.7.85, dna integrity scanning protein disa is a dna binding protein participates in a dna-damage check-point. disa forms globular foci that rapidly scan along the chromosomes searching for lesions. catalytic activity this enzyme has diadenylate cyclase activity, catalyzing the condensation of ... | wikipedia |
2c337b3f4f22f8f237ffb98e06bc6d9fac8756a9 | this enzyme has diadenylate cyclase activity, catalyzing the | this enzyme has diadenylate cyclase activity, catalyzing the condensation of 2 atp molecules into cyclic di-amp (c-di-amp). c-di-amp likely acts as a signaling molecule that may couple dna integrity with a cellular process. this rate-limiting step is the accessibility of the active site; mutating the possible exit tunn... | wikipedia |
b233a12d1a5968d6800a0c8e8a740e76b2e013db | diadenylate cyclase ec 2.7.7.85, dna integrity scanning protein | diadenylate cyclase ec 2.7.7.85, dna integrity scanning protein disa is a dna binding protein participates in a dna-damage check-point. disa forms globular foci that rapidly scan along the chromosomes searching for lesions. catalytic activity | wikipedia |
c8cea6dfa5618652db27b26f06d6ca3d1d4d0795 | casa linda plaza, its official name, was the | casa linda plaza, its official name, was the brainchild of carl martin brown and his son howard d. brown. the east dallas family farm land of 600 plus acres was purchased in 1937. the abstract completed at that time traces the ownership of the land back to the original owner who had been rewarded the land for his servi... | wikipedia |
2a1dc05cb7da18a7bf708358f0977508a8f6ce7a | casa linda plaza, its official name, was the | c & s hardware, skillern's drug store, reynolds-penland, el fenix (restaurant), zenith televisions, ashburn's ice cream, wyatt's cafeteria, parisian-peyton's, colberts, mr and mrs gift shop, vavra's bakery store, time jewelers, jackson's sporting goods, varsity shop, degeorge's barbecue, fred's barbecue, maple shop (f... | wikipedia |
b5e0c83fe1908dc70f1f36466e850273fe9cdfa1 | the highland park cafeteria was unfortunately forced to | the highland park cafeteria was unfortunately forced to close permanently, during the summer of 2020, due to the coronavirus pandemic. all furniture, equipment, signage, etc. was auctioned off. with the shuttering of highland park cafeteria’s last existing location, it brought to an end their 95-year legacy. | wikipedia |
bb67976501aad3b166cdec8be5095aa950563f7b | hopkins-shafer purchased the property in the 1980s and | hopkins-shafer purchased the property in the 1980s and painted the buildings bright pink. since then, the center went through several changes in ownership. in 2008, the shopping center changed hands again, selling to a company called amreit, which began renovating the center in march 2008. according to the company webs... | wikipedia |
126849125e0009432b7da5c2ea12c6538976b0c3 | among the first tenants were tom thumb grocery | among the first tenants were tom thumb grocery store, mott's variety store, c & s hardware, skillern's drug store, reynolds-penland, el fenix (restaurant), zenith televisions, ashburn's ice cream, wyatt's cafeteria, parisian-peyton's, colberts, mr and mrs gift shop, vavra's bakery store, time jewelers, jackson's sporti... | wikipedia |
bf4f9bea9dbc98cb0e042c2b56db5b752d9fe926 | carl brown started buying the land in the | carl brown started buying the land in the early 1930s and eventually owned over 1,000 acres of prime residential and commercial property in east dallas. building was started before world war ii and resumed after howard brown returned from his active duty in wwii in february 1946. due to the war, construction materials ... | wikipedia |
9c847ed85c3b65cacc42b3a576d7d176922b02ca | casa linda plaza, its official name, was the | casa linda plaza, its official name, was the brainchild of carl martin brown and his son howard d. brown. the east dallas family farm land of 600 plus acres was purchased in 1937. the abstract completed at that time traces the ownership of the land back to the original owner who had been rewarded the land for his servi... | wikipedia |
bc532f14fcb107c6f8d2d137f5393d91354c747c | diadenosine hexaphosphate hydrolase (amp-forming) is an enzyme with | diadenosine hexaphosphate hydrolase (amp-forming) is an enzyme with systematic name p1,p6-bis(5'-adenosyl)hexaphosphate nucleotidohydrolase (amp-forming). this enzyme catalyses the following chemical reaction a divalent cation is essential for activity. | wikipedia |
437a89006338f615cd744b20fbfb3193e3eeab79 | diadenosine hexaphosphate hydrolase (amp-forming) (ec 3.6.1.60, haps1, nudt11 | diadenosine hexaphosphate hydrolase (amp-forming) (ec 3.6.1.60, haps1, nudt11 (gene), haps2, nudt10 (gene)) is an enzyme with systematic name p1,p6-bis(5'-adenosyl)hexaphosphate nucleotidohydrolase (amp-forming). this enzyme catalyses the following chemical reaction | wikipedia |
7736c429ca3d73674bf04dc264b458d475b39d1f | donald william smillie was a professional ice hockey | donald william smillie was a professional ice hockey player who played twelve games in the national hockey league with the boston bruins during the 1933–34 season. the rest of his career, which lasted from 1933 to 1936, was spent in various minor leagues. smillie got the first of his two nhl goals on march 6, 1934 in b... | wikipedia |
085cdd60f60ddb651e19ceaefc9dbcfa358dcc6b | donald william smillie (september 13, 1910 — june | donald william smillie (september 13, 1910 — june 15, 1993) was a professional ice hockey player who played twelve games in the national hockey league with the boston bruins during the 1933–34 season. the rest of his career, which lasted from 1933 to 1936, was spent in various minor leagues. | wikipedia |
6de2815e1f8a1f7df5b713dbdd1bbf572862e8a9 | fg-8205 (l-663,581) is an imidazobenzodiazepine derivative related to | fg-8205 (l-663,581) is an imidazobenzodiazepine derivative related to bretazenil, which acts as a partial agonist at gabaa receptors, with slight selectivity for the α1-containing subtype. in animal tests it has anxiolytic and anticonvulsant effects but with little sedation or ataxia produced. | wikipedia |
823f42bddf95eea623da7ee3513a585a54ed38a4 | fg-8205 (l-663,581) is an imidazobenzodiazepine derivative related to | fg-8205 (l-663,581) is an imidazobenzodiazepine derivative related to bretazenil, which acts as a partial agonist at gaba receptors, with slight selectivity for the α -containing subtype. in animal tests it has anxiolytic and anticonvulsant effects but with little sedation or ataxia produced. | wikipedia |
7d20015fa171c357d4e7bdfe84380fd45159b6c7 | the pharmacological properties of this drug have not | the pharmacological properties of this drug have not yet been fully explored but currently suggest that it may be a more potent anti-cancer agent than other chemotherapeutic drugs. the bacterium is believed to use dynemicin a as an antibacterial agent to help it survive in its niche in the environment. dynemicin a, as ... | wikipedia |
a6d868234edcc24d408954a74a7a3d8bdecd14b0 | dynemicin a is specific for b-dna, and functions | dynemicin a is specific for b-dna, and functions by intercalating into the minor groove of the double helix. for intercalation to occur, the separation between strands, which is usually 3-4 angstroms, needs to be widened to 7-8 angstroms to allow enough space for the ligand to bind. given this, the dna must be strained... | wikipedia |
076921363baabb7ead9b09525eedaa183ee4e642 | dynemicin a is an antitumor natural product isolated | dynemicin a is an antitumor natural product isolated from micromonospora chersina which causes dna strand cleavage. iwasaki et al. first studied the biosynthetic pathway of dynemicin a by c nmr labeling experiments. dynemicin a is thought to be biosynthesized separately from two different heptaketide chains originated ... | wikipedia |
b77ee1baca8a85f35c9e534b9d806969cee68325 | dynemicin a was first isolated from the soil | dynemicin a was first isolated from the soil in the gujarat state of india. it was discovered to be the natural product of the indigenous bacteria micromonospora chersina. the natural product displays a bright purple color due to the anthraquinone chromophore structure within it. initially, this compound was isolated f... | wikipedia |
ebe7b5a7d6ce5af4a95621e56bb9877b51d4cb83 | after her phd, stoeckli stayed in the laboratory | after her phd, stoeckli stayed in the laboratory of professor peter sonderegger for two more years as a postdoctoral fellow from 1990 to 1992. afterward, she moved to cleveland to join the laboratory of professor lynn landmesser at the case western reserve university in 1993, where she studied the guidance of chick com... | wikipedia |
7adc5388883662787853ea6fa85d87f0d021695d | stoeckli pursued her undergraduate studies in biochemistry at | stoeckli pursued her undergraduate studies in biochemistry at the university of zurich in 1980 and then followed with her doctorate studies in the same department under the supervision of professor peter sonderegger. her ph.d. thesis was devoted to the identification and characterisation of proteins secreted from axons... | wikipedia |
496810668d8f2fe6981d2c19816bc9712682db4d | in computing, esatap is a combination connection for | in computing, esatap is a combination connection for external storage devices. an esata or usb device can be plugged into an esatap port. the socket has keyed cutouts for both types of device to ensure that a connector can only be plugged in the right way. | wikipedia |
c71bd3fa4e68a3d057630f2bc3af4c7b9a0a1eec | if the smaller side of this cable is | if the smaller side of this cable is plugged into a "powered" esata port, providing both 12 v and 5 v, then the wide end may be plugged into a 2.5" or 3.5" sata hard drive, supplying the bare drive with both signal and power. the small 2.5" drive will get signal and power at 5 v, which is all that the smaller drive req... | wikipedia |
7e02212ee8198ad1a313d739d9cacf124206ec45 | esatap cables are available with wide connectors to | esatap cables are available with wide connectors to plug directly into the power and signal connectors of a bare drive, providing a 12 v supply in the case of a desktop machine. a version of this wide connector is found inside every external sata hard drive enclosure; when the hard drive is slid inside, it mates with a... | wikipedia |
b7c56826a28d59cad50be787fff302217ff62e48 | there are only two versions of this port. | there are only two versions of this port. most laptop computers do not have 12 v power available, and have an esatap port which provides only 5 v. desktop computers, with 12 v available, have a port with two additional pads, placed against the plug's "horns", which provide 12 v. some manufacturers refer to these ports ... | wikipedia |
a4dceb8dcd331f61f2a955dbe54e8a86c0fbca80 | esatap throughput is not necessarily the same as | esatap throughput is not necessarily the same as sata, many enclosures and docks that support both esata and usb use combo bridge chips which can severely reduce the throughput, and usb throughput is that of the usb version supported by the port (typically usb 3.0 or 2.0). esatap ports (bracket versions) can run at a t... | wikipedia |
7be98a2bbd5b4db25e5a0719fe8cd6e2918c79ef | on many notebook computers only a limited amount | on many notebook computers only a limited amount of power at 5 v is available, and none at all at 12 v. devices requiring more power than is available via the expresscard, or an additional 12 v supply as required by most 3.5" or 5.25" drives, can be driven if an additional power supply is used. cables are available to ... | wikipedia |
195b4f1473e887942e54a2a8676429a8cae7b0b4 | if advanced functionality such as a port multiplier | if advanced functionality such as a port multiplier is required, a pci express add-on card can be used. if it has port multiplier support, an esatap port allows a user to connect to a multi-bay nas (network attached storage) machine with multiple hard disks (hdd) using one esata cable. | wikipedia |
0ef5f6b7d26f373dad301da5a0883f8fbaf45bf5 | on a desktop computer the port is simply | on a desktop computer the port is simply a connector, usually mounted on a bracket at the back accessible from outside the machine, connected to motherboard sources of sata, usb, and power at 5 v and 12 v. no change is required to drivers, registry or bios settings and the usb support is independent of the sata connect... | wikipedia |
b530750a0f4b82c76c6603b9ac3c17504090f878 | sata is a computer bus interface for connecting | sata is a computer bus interface for connecting host bus adapters to mass storage devices such as hard disk drives and optical drives. esata is a sata connector accessible from outside the computer, to provide a signal (but not power) connection for external storage devices. | wikipedia |
ba7d99881b1d3809f4951c0d561b3dd76f53522b | as the port is designed to work with | as the port is designed to work with both sata and usb, both organizations have formally approved it. the usb implementers forum states it does not support any connector used by other standards, hence such 'combo' ports are to be used at one's own risk. as of 2011 the organization responsible for the sata specification... | wikipedia |
ba154ead19f9a711f46b3ecb3773ba9aae80eadd | in computing, esatap (also known as power over | in computing, esatap (also known as power over esata, power esata, esata/usb combo, esata usb hybrid port / euhp) is a combination connection for external storage devices. an esata or usb device can be plugged into an esatap port. the socket has keyed cutouts for both types of device to ensure that a connector can only... | wikipedia |
c466bfafd39ba384a7e52ea04122e9c63d1ba505 | charles glen king was an american biochemist who | charles glen king was an american biochemist who was a pioneer in the field of nutrition research and who isolated vitamin c at the same time as albert szent-györgyi. a biography of king states that many feel he deserves equal credit with szent-györgyi for the discovery of this vitamin. | wikipedia |
ebaab962683fa7cba6c7672037d0d2c01427782a | apart from his work with the nutrition foundation, | apart from his work with the nutrition foundation, king's public service activities involved creation of the usda 's plant, soil, and nutrition laboratory in ithaca, new york. he helped establish the food and nutrition board, dealing with food and nutrition problems in military and civilian populations, beginning in wo... | wikipedia |
f887586e7247e344360f22ec665c4e00efbb64a9 | king's contribution to the science of nutrition revolves | king's contribution to the science of nutrition revolves around his isolation of vitamin c in 1931-1932 by studying the antiscorbic activities of guinea pigs with preparations from lemon juice. albert szent-györgyi was conducting similar research at the university of szeged in hungary, focusing on hexuronic acid. the c... | wikipedia |
a331d43852290f29397aa0316afbf8298d5e182c | king was born in entiat, washington to charles | king was born in entiat, washington to charles clement king and mary jane bookwalter. he entered washington state university early, as his local one-room school did not have a twelfth grade. he was a member of lambda chi alpha. world war i interrupted his college studies, where he served in the 12th infantry, a machine... | wikipedia |
27f5db029326555cc82f8f54de88035bfe0b8cf8 | charles glen king (october 22, 1896 – january | charles glen king (october 22, 1896 – january 23, 1988) was an american biochemist who was a pioneer in the field of nutrition research and who isolated vitamin c at the same time as albert szent-györgyi. a biography of king states that many feel he deserves equal credit with szent-györgyi for the discovery of this vit... | wikipedia |
c370ed610e32bcca5dd001c0d61ea27a9fd23129 | the infallible pistol was a .32 acp caliber | the infallible pistol was a .32 acp caliber handgun manufactured by the davis-warner arms corp during the early 20th century. when warner arms co. could no longer get the schwarzlose model 1908 pistols from germany, they had .32 pocket pistols made in the united states in three variations. the front sights and the grip... | wikipedia |
e37b4579f3c86add573699010501eba027ce1ea0 | they had one serious drawback. at the back | they had one serious drawback. at the back of the guns there is a small lever and a push-through pin. if the shooter disassembled the pistol and forgot the turn that lever the right way or forgot to push the pin all the way in, the breechblock would be stopped only by a small projection and could come back in his face.... | wikipedia |
03a9f25fb29a056573c2f7eddf61bedc62293cb1 | the guns were called the "davis-warner infallible", and | the guns were called the "davis-warner infallible", and their trademark was "blocks the sear", a reference to the way the safety worked. unlike the schwarzlose m1908, the davis-warner guns are fairly conventional, striker-fired, blowbacks, using a breechblock rather than a slide, though, since browning had patented the... | wikipedia |
3f939b1d07b28d5e26358535356f0c971d608306 | when warner arms co. could no longer get | when warner arms co. could no longer get the schwarzlose model 1908 pistols from germany, they had.32 pocket pistols made in the united states in three variations. the front sights and the grips that there was a conscious effort to imitate the outline of the schwarzlose. | wikipedia |
85a5216e1c0edfb471fae932c203636d83ecc513 | the routh array is a tabular method permitting | the routh array is a tabular method permitting one to establish the stability of a system using only the coefficients of the characteristic polynomial. central to the field of control systems design, the routh–hurwitz theorem and routh array emerge by using the euclidean algorithm and sturm's theorem in evaluating cauc... | wikipedia |
309ecb2630420487fd07fbac411684ea6af4fd03 | in order for all the roots of the | in order for all the roots of the polynomial f (z) {\displaystyle f(z)} to have negative real parts, it is necessary and sufficient that all of the elements in the first column of the routh scheme be different from zero and of the same sign. | wikipedia |
2df6b416ce73296a401b5f42637143b5778ba757 | and for the stable case where p = | and for the stable case where p = 0 {\displaystyle p=0} then v (a 0, b 0, c 0, d 0, …) = 0 {\displaystyle v(a_{0},b_{0},c_{0},d_{0},\dots)=0} by which we have routh's famous criterion: | wikipedia |
ac75f63e8e676c0594af5072e920730676879946 | the number of roots of a real polynomial | the number of roots of a real polynomial f (z) {\displaystyle f(z)} which lie in the right half plane r e (r i) > 0 {\displaystyle {\mathfrak {re}}(r_{i})>0} is equal to the number of changes of sign in the first column of the routh scheme. | wikipedia |
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