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11300117-0136-10.layout.json
[ "83.", "84.", "85.", "86.", "87.", "88.", "89.", "90.", "1.", "92.", "93.", "94.", "95,", "McCarthy,", "£.,", "0'Connell,", "D.,", "LaForce,", "M.", "and", "Huber,", "G.:", "How", "much", "oxygen", "1s", "toxic?", "Clin.", "Res.", "21:666,", "1973.", "Dodd,", "M.,", "Johnson,", "S.,", "Harris,", "L.,", "O'Connell,", "D.,", "Finder,", "E.,", "LaForce,", "M.", "G.:", "Recovery", "and", "adeptation", "of", "the", "Tung", "to", "injury", "induced", "by", "prolonged", "exposure", "to", "100%", "oxygen.", "Clin.", "Res.", "21:659,", "1973.", "O'Connell,", "D.,", "Huber,", "G.,", "Simmons,", "G.,", "Barrett,", "I.,", "LaForce,", "M.", "and", "Mullane,", "J.7", "Chest", "strapping,", "bacterial", "infection", "and", "the", "A", "model", "for", "experimental", "respiratory", "acidosis.", "Clin.", "Res.", "21:670,", "1973.", "McCarthy,", "C.,", "O'Connell,", "D.,", "Finder,", "E.,", "Simmons,", "G.", "and", "Huber,", "G.:", "The", "effect", "of", "prolonged", "exposure", "To", "100%", "oxygen", "on", "the", "intrapulmonary", "inactivation", "of", "various", "bacterial", "pathogens.", "Clin.", "Res.", "21:607,", "1973,", "Huber,", "G.,", "0'Connell,", "D.,", "McCarthy,", "C.,", "Birns,", "R.", "and", "Mullane,", "J.:", "The", "effect", "of", "oXygen", "administration", "on", "aspiration", "pneumonitis.", "Clin.", "Res.", "21:662,", "1973.", "Huber,", "G.,", "0'Connell,", "D.,", "McCarthy,", "C.,", "Birns,", "R.,", "LaForce,", "M.", "and", "MuITlane,", "J.7", "Oxygén", "administration", "and", "antibacterial", "defenses", "of", "the", "lung", "in", "experimental", "congestive", "heart", "failure..", "Clin,", "Res.", "21:426,", "1973.", "Mullane,", "J.F.,", "LaForce,", "F.M.,", "0'Connell,", "D.M.", "and", "Huber,", "G.L.:", "Acute", "bIood", "1655", "and", "puldonary", "host", "defense", "mechanisms", "in", "the", "rat.", "J.", "Surg.", "Res.", "14:228-234,", "1973,", "Popovic,", "N.A.,", "Bielke,", "S.R.,", "Huber,", "G.L.", "and", "Mullane,", "J.F.:", "Pulmonary", "ultrastructural", "changes", "after", "aspiration", "oF", "bTood.", "Proc.", "Elect.", "Microscopy", "Soc.", "Am.", "31:406-407,", "1973.", "Mullane,", "J.F.,", "Liang,", "J.C.,", "Popovic,", "N.A.", "and", "Huber,", "G.L,:", "Alveolar", "septal", "edema", "with", "experimental", "biliary", "obstruction.", "Gastroenterology", "64:887,", "1973,", "Mullane,", "J.F.,", "LaForce,", "F.M.,", "Wilfong,", "R.G.,", "O'Connell,", "D.M.", "and", "Huber,", "G.L.7", "Tntra-alveolar", "blood", "and", "pulmonary", "antibacterial", "defense.", "Am.", "Rev.", "Resp.", "Dis.", "107:1093,", "1973,", "LaForce,", "F.M.,", "Mullane,", "J.F.,", "Boehme,", "R.F.,", "Kelly,", "W.J.", "and", "Huber,", "G.L.:", "The", "effect", "of", "pulmonary", "edema", "on", "antibacterial", "defenses", "of", "the", "lung.", "J.", "Lab.", "Clin.", "Med.", "82:634-648,", "1973,", "LaForce,", "F.M.,", "Kelly,", "W.J.", "and", "Huber,", "G.L.:", "Inactivation", "of", "staphylococei", "by", "alveolaT", "macrophages", "with", "preliminary", "observations", "on", "the", "importance", "of", "alveolar", "lining", "material.", "Am.", "Rev.", "Resp.", "Dis.", "108:784-790,", "1973.", "Mullane,", "J.F.,", "LaForce,", "F.M.", "and", "Huber,", "G.L.:", "Variations", "in", "lung", "water", "and", "puTmonary", "host", "defenses.", "Am.", "Surg.", "39:630-636,", "1973.", "Voo", "2kl", "W", "oo", "b", "o", "e", "s", "e", "T", "vk", "il", "S", "i", "b", "Do", "bl", "i", "11300127", "v", "Vv", "Bl", "i", "Lo" ]
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521826392+-6403-5.layout.json
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514050868+-0907-31.layout.json
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508939370_508939517-83.layout.json
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521513430+-3444-7.layout.json
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505990904.layout.json
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508939370_508939517-97.layout.json
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508939370_508939517-111.layout.json
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500441172+-1192-11.layout.json
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0001007338-5.layout.json
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500692166_500692218-47.layout.json
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513839252_513839291-9.layout.json
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508939370_508939517-86.layout.json
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502835948+-5959-7.layout.json
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50119548-9557-8.layout.json
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2078020292.layout.json
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0001461870-0.layout.json
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511781859_511781868-4.layout.json
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0001039501-98.layout.json
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"Bloom", "(34)", "developed", "a", "similar", "par-", "tial", "restraint", "and", "catheter", "protection", "system", "involving", "a", "leather", "vest", "and", "fiexible", "vinyl", "covered", "conduit.", "Methods", "for", "drug", "self-administration", "in", "un-", "restrained", "monkeys", "have", "been", "reported", "by", "Thompson", "&", "Pickens", "(38).", "In", "this", "method", "monkeys", "are", "fitted", "with", "a", "leather", "vest", "and", "an", "aluminum", "backs", "pack.", "The", "back-pack", "contains", "2", "radio", "receiver", "and", "miniature", "infusion", "pump.", "A", "signal", "from", "a", "remote", "transmitter", "is", "used", "to", "activate", "the", "infusion", "pump.", "Ry", "using", "receivers", "tuned", "to", "different", "frequencies,", "several", "animals", "can", "live", "in", "a", "common", "experimental", "space", "and", "independently", "or", "concurrently", "self-ad-", "minister", "drugs.", "VARIABLES", "INFLUENCING", "THE", "SELF-ADMINISTRATION", "OF", "DRUGS", "In", "this", "section,", "studies", "designed", "to", "determine", "the", "pharmacological,", "vr-", "genismic,", "and", "environmental", "variables", "affecting", "drug", "self-administration", "are", "reviewed.", "It", "is", "impossible", "at", "this", "point", "in", "the", "development", "of", "this", "re-", "search", "to", "specify", "how", "these", "variables", "interact", "or", "how", "they", "affect", "the", "self-", "administration", "of", "different", "classes", "of", "drugs.", "However,", "this", "review", "may", "help", "to", "stimulate", "research", "by", "pointing", "out", "the", "deficiencies", "in", "our", "knowledge.", "VHARMACULOGICAL", "VARIABLES", "Pharmacological", "compaunds", "shown", "to", "be", "reinforcers—Just", "as", "food,", "electrical", "stimulation", "of", "subcortical", "brain", "structures,", "and", "the", "opportunity", "to", "engage", "in", "sexual", "hehavior", "all", "have", "different", "reinforcing", "properties,", "one", "might", "expect", "different", "drugs", "to", "have", "different", "reinforcing", "effests.", "The", "car-", "liest", "evidence", "suggesting", "that", "drugs", "might", "serve", "as", "reinforcers", "was", "Sprage’s", "(36)", "repot", "that", "physically-dependent", "chimpanzees", "would", "engage", "in", "behavior", "which", "Jed", "to", "the", "experimenter’s", "administration", "of", "morphine", "Thotgh", "sustained", "self-administration", "was", "not", "part", "of", "this", "study,", "the", "data", "suggested", "that", "morphine", "administration", "maintained", "the", "drug-directed", "be-", "havior.", "Beach", "(37)", "made", "a", "similar", "observation", "in", "rats", "using", "a", "T-maze.", "The", "first", "study", "demonstrating", "that", "morphine", "served", "as", "a", "reinforeer", "in", "rats", "was", "by", "Headlee,", "Coppock", "&", "Nichols", "(3).", "Further", "morphine", "self-administration", "studies", "have", "been", "conducted", "by", "Weeks", "(27,", "30),", "Schuster", "&", "Thompson", "(29),", "and", "Yanagita,", "Deneau", "&", "Seevers", "(28).", "Subsequent", "reports", "by", "Weeks", "&", "Coltins", "(38),", "Thompson", "&", "Schuster", "(39),", "Collins", "&", "Wecks", "(40)," ]
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bap06a00.layout.json
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2073874045_4052-2.layout.json
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2022161585_2022161648-38.layout.json
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2046807567_7643-64.layout.json
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504221516_504221531-15.layout.json
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504989552_504989561-9.layout.json
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518415175+-5177-2.layout.json
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50119548-9557-7.layout.json
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0001039501-89.layout.json
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2022161585_2022161648-7.layout.json
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500692166_500692218-49.layout.json
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82834937_4954-12.layout.json
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524860047+-0116-15.layout.json
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506320540_506320542-2.layout.json
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2505531228_1235-3.layout.json
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11277228.layout.json
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502835948+-5959-4.layout.json
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2077456508_6510-1.layout.json
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11300117-0136-18.layout.json
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