id int64 | subtask string | question string | options list | answer_index int64 | answer_text string | metadata string |
|---|---|---|---|---|---|---|
401 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? TCCCCGCTCCTTTTCAGGAACTAGAATTCGTGCCTTGTAATCCGCGCCACCGTGAAAGCATCCCTCAGCGCGCCGCGCCCGCGCACTCGCCCCGCTCACG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
402 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GTGTTCTCTCCGTCCCCGATCCACTCGGGCTCCGGCAGCTGCTGCTTGGGCGCCTTCGGCATCGCGGTGGCAGAACTAGAAACGAGTTACAGATAGAAA... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
403 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the STAT1 transcription factor? TCGGGGTCTCCCGGGCGACCGCACAAGCGTCGGCGTCCTTAGCGTTCCGCCGGTTTAGGCGGAGGCGGAGGCGGAGCGTTTGGGGGCGGCCGGGGCGGCT | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "STAT1", "true_labels": ["EGR1", "NRF1"]} |
404 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CAGCCTAGGATTTTCAGAGTAATGTGAGTGCTGTCATCTGAGCCCCCCTTACTGCTTCAGATGATACAAACAGTGACCAATGGTCCGAGATGAAGTGTAA | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
405 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CTGTCAACACAGTTCATCTTAATGACTCATCATTCTGTCATCTGCTGCCCTCTACTGGAAAAGAATACATATAGCCAACAGTGTGGTCCAGAATCCAGA... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
406 | 5_tfbs | Is the provided Human DNA sequence a target for the SRF protein? GCTTGATAGCAAACCACACTCGGCACAGGAAGGAGAACAGCGCCCGCGGCCCCGGGCCTCCATGAAATCAGCAAGGGCGCGCTCCTCCCACCGCCGCGCT | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "SRF", "true_labels": ["GABPA", "SP1"]} |
407 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? TCCACCGTTCCCCTCAAGCTCACCAGAAAGGGTGCAGCCTCTTATCTAGGCAAAACAGGCCCTTCAAATTTTCACCGGAAACAAAAAGGTCAGCTTTCTC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
408 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CTCTTTTGATTGTGAACTACCTGAGCCACTGTGTTGTTAAGGGCATCTGCCATTAGAGGGCAGAAGTTGCCTAGACTTAGCCTCCGCAAATATTACGATT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
409 | 5_tfbs | I need to know if STAT1 is likely to bind to this DNA fragment: CAGCAGAGAAGATGCCAAAATTTTGTATTTACTGTCAGGGCAATGATGCTGGAACTGCAGATCCAGCGCCCCGAAACCCGGCCCATCCCAAGACACTGCT | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "STAT1", "true_labels": ["SP1"]} |
410 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TTCGCCCAGAGCCCCCCACCCGGGCCGTGACCTGGTCTGTGGCCTCCGCTCCGGAGCCCAAGTTCCGCGTCTTCCCTGCTTTCGGCTGGGGGTGGGGTGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
411 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GAACTAGCACACACTGGGGCGGGGTCGCCAGGGCGTGAGGCTTCAGCACCACAGACAGCAATCCGACAGTCCGGTCGAGGGCGCTGCCGGCGAGGTAGC... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
412 | 5_tfbs | Is the provided Human DNA sequence a target for the E2F1 protein? GTGGCCAGGAAGGGCTCTCTCAAAGGTGACATTTAAGCTGAGTTCTGAAGGAATGAGATGGAGCCAGGCATTGGAAAAACAGTTATCATGACGATAAGAC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "E2F1", "true_labels": ["GABPA"]} |
413 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? AGGAATAAGAGTCATGCACCTGATAGACATCTTAGGTGCCCCACCAACCATTATCTAGTTCTTCTACACTAAGACAGAGTACTCACCAGGATCCTAACAC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
414 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TGGCCACTGAGTGCCACGGAAGCGCCTGTCACCACAGGAAGCCCCACGGCTTTGCCACGGCCTTGTCTACAGAGGCAGCCACTGCCTTCCAGAGGCCAG... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
415 | 5_tfbs | Is the provided Human DNA sequence a target for the REST protein? CTTTGCTCTCATTCGCACTATGGTCAGGAAAGGAAACCATTTCTCTCTCTGAAAAGAGGAAGTGAATTTTTTTGTGGTTTAAGCAAAGTTTGTAATTAAA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "REST", "true_labels": ["REST", "GABPA"]} |
416 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? AGATCTAGTGCGGTTCGTTCCGAGGCACCACCATGTTGGGCTGTCGGCCTCTCACCGACTTCTTGGGTCCGTACCTGCGGCATGTGTCTGTTTAAGTGTC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
417 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CCGGCCGCCTCGTTGCTGGCAGCGCTTCCGCCCGCCGGCGCACCAGTCAGTACCGCGCCCGGCGAATGTGGAGGGCGAAGCTGCGGCAGGGCAATCACA... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
418 | 5_tfbs | Can you confirm the presence of a MEF2A TFBS in this Human DNAsequence? GTTTAGTGTGGCAGAAGATGAAAGAACCGGACAGGAATACGGACGAAATTGGAGCAGGGTTTGGGCTCTCCCCTTCGCAGATAATGGGAGGAGCCGGGCC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "MEF2A", "true_labels": ["SP1"]} |
419 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? CCCCCGCCATCCCGCTCGCTCCCCTTCGGCGGCCTCGCTCCACCGCCCCGCCACGCGTCCGAGCGGGCTCCGTAGCCTACCGCAACCGCGCGCGGAGCTG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
420 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? ATTATCTATGTACCGCCTCTCAGCTTCAAATACACCCACGGAGTTAAGCTTTGTCAACAGAGGGCGCCGGAGAGTCACTGCAGGAGGGACGGTCTCCTGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
421 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: CGGAACATCGCAAACGAGTCCCGGCCAACCCCCTCCCCTCAAACTCTTCTCGGGACCCCTTTCTTCACAGTTATTTGGTCGATGAGGCAAGAGATCAAGG. Is this a NR3C1 binding site? | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "NR3C1", "true_labels": ["SP1"]} |
422 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? AGAGATTTAATAATTCTAGCAAAAAAAGAAGAGAAAAAAAATACAGAAGAAAAAAAAAAAGAAAACAGGAGCTTATAGAAAGTAAGATAATGAAAATTTT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
423 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GGAATTTCGTGATGTTCCCTGCCTGAGCTTCGGGGAGGGCGGGGGAGTGCTGTAAGGGGCTATCGCGCAAGTGCAGACCCTCTGCTTCTGCCGCAAACG... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
424 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the MAX binding profile? TACATTTTTTAATTGTAGAAAAGGCAAGTTGTGTGGCTGCTGACCTTGGTCCTGAATGGTAGCTAAAGTACTGTTTTCTGAGAAGAGTGTTGAAGGGGGT | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "MAX", "true_labels": ["REST", "STAT1"]} |
425 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? TCAACCAATTTCAGCAATAAGGCCAGTCCCCAGGGCATCGCAGCCAGAGTAGTGACTGCCGGGACACCAAAGCCATCCCCTACGGCCAGATAGGACCCGC | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
426 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TCCTGGGGTCCCGGCCACCTGGGGAAGCCGCGCCTGCCAAGGAGGCCACCAGAGGGCAGTGCAGGCTTCTGCCTGGGCCCCAGGCCCTGCCTGTGTTGAA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
427 | 5_tfbs | Hypothesis: The transcription factor STAT1 binds to the following Human DNA sequence. Is this true? GTCATTGGAGATGGATTTTGAAGTGAGGAAGAATGTCTAAAGGCACATATGGGGAAGCAAGATAAGAAGAAGGTAGGAGTGTGCAGGAAGGAAAGTACTC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "STAT1", "true_labels": ["GATA2"]} |
428 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TATAGAAGGATGGAACTCTGTATGTGAGTCAGCAATAGTGGATAAGGGCAGAAATTAACAGGATGTTTTGAGAGTGGCAATAAATTAACCCAATCCTCTT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
429 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TATCACCAGAGCGCTTGACAGCCCCCTGTTGGGAGAGGATAGAATGTTCTGAGCTGGGACACAGGCTTTACACAATCTTGTCATCTGCTTAGCCACTTGT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
430 | 5_tfbs | I need to know if SP1 is likely to bind to this DNA fragment: AATTTACTGAGGTGGAAAGATTGCGGGGTCATTGTGGGGTCAGGCTGAGGGGGCCGGGCCCAGCCCTATTCACGTGACCCGGTCCCAGGGAGAGGAGTTT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "SP1", "true_labels": ["REST", "SP1"]} |
431 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? GAAACACACCCTTGTGCTTATATCAACGGCTTTCTTCCAGGAAGCATGGCACTGCTTTCAGAGCATGCACACATTGTTATCTTGTCTGTTCGAGGGAAGT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
432 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TCTTTCATTATCTGTTATAATTTTGCAATGGCGGTTTCAACCTAGTGGCCGAACCCGTCCCATCCATCTCCCGCGCCCCTCCGCTCCACCACAGCCCTCG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
433 | 5_tfbs | Is the provided Human DNA sequence a target for the TEAD4 protein? TTTTGGGTTTCACTAGATTTAAAGCAGAAGTGAGGCTTCATTACAAGGCCACCTCTCTTTTCTGACTAGTGGGGTTTTAAATAGCCTGGTGGCTTTCCAG | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "TEAD4", "true_labels": ["RELA"]} |
434 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? AAGGGCCTCTCCTGACCCCATTTTTCTCCTTCCGGAGCGCTCCGCAGAGCACCAACTGGGAAAGCGAGGGCGCCCCAAACCAGAGCCGGAGGCACCCTCT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
435 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? ATTTGTGTGGGTCTGTGGATGGCCATCTACTGGTCTTTCACTGCAATGACAGTGTCATCCTACTTTCTCCAAAAGGAAATTTACAGCAGTCAAAAACTAC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
436 | 5_tfbs | Hypothesis: The transcription factor JUN binds to the following Human DNA sequence. Is this true? CACTCCAGGCAGGCGACAGGTGACAGGTGATCACGCCCCCTCAACGCCGCCGGGGCCCACAAGGCCCCGCTCCCTATGAGTTCAGTCCTGCCCCAGTGAT | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "JUN", "true_labels": ["EGR1"]} |
437 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? AGCTGAAACCCTGGCTTAGGGGAAGAGGAACCGCCTGGGAGGGGCTGGGGGAGATCCTGGGTTCCCCTCTGGCACTAACCAATGTGGCCACCAGAGGGCG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
438 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CATGGCCTGCAGGTGGCGCAGGTTGGCACCGTGCGCCTGATGTCCGGGCACTGCGCGCCTCCAGAGCGTGAGGCCGATGACGCTGTAGGCTACAAACATC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
439 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the CTCF binding profile? CTGGTGGAAATCGGTGGAAGGGCACTAAGAAGGGGACTGACTTGGCCAGATGGAGATTGGCCACAGGGTGGTGCTGTGGAGGCAGATTTGAAGGTGAGGC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "CTCF", "true_labels": ["CTCF"]} |
440 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? TTATTTTTAGACGAGCATCTTCAAAAGAGCAAGCTGGAAGATAATTTGCATGCATCTTTCCATCATCTTTCATTTCTTGTTTTCACCAAGTATAAAGACT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
441 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CGGCTGGCGCGCAAGGCCTGCTGGGGCTTGTAGTCTAGACCACTTCCGCGCTCAGGCGCCTGCGCTTTAGCTGCTAACTCGCTCTAGTAGCTGTGGTCGG | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
442 | 5_tfbs | Hypothesis: The transcription factor E2F1 binds to the following Human DNA sequence. Is this true? AGCCTTCCCTCCCCAGCTGCCGAGGCCTGTGAAAATGGCGCCACCTGTCGGCCAGGCTCAGGATGGCGTCTGAGTCCCGGACCGGGATGTGCGGGAGGGC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "E2F1", "true_labels": ["CTCF", "E2F1", "SP1", "YY1"]} |
443 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GACAGCTTTGAACTGGCGCGCCGGACACTCGAAATCTAAACGACAGTCCAAAACCGCCCCGCAGGCAAAAGCAACAATCCTACAAGACACTCATCCCCGA | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
444 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? AGCACGGGTCTGAAAGGGCAGGTGCCTGTCCTGGAAACCACCTTCTCTTGGGGCATCCCCTGGCTGCCCTTCTGCCTGTTGCCACCAGGTGGGGCTCTCT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
445 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: CAACACAGTAGAATATAGGCTTCATGGTTGGAGTTTCAGCGGCCATCTTGGACCATGAGGTGACCTTGGGAATGGAAACCATAGAAGATGCCTAGGTTTC. Is this a FOXA1 binding site? | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "FOXA1", "true_labels": ["YY1"]} |
446 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GGGCCCGCGAAAAGCTTCCTCTTAGCGGCTGGTGATGCATGACGAGGGTTCGGGCGCTCAAGCTGACCTGGCACGCTTCCTGCGGCTCGTTGGTAGGTCG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
447 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GCCAACTACATGGATAATAAAGAAAAAAATGAGAATTTTAAAGCTAAAAGACTCCTACTGGCCAATTTTGAGTACTTCCTGAGGATGAGACACTTTCCAC | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
448 | 5_tfbs | Is SP1 occupancy expected at this locus based on the Human DNA sequence provided below? CTGGCAGTTGTGAACTCGAACCTGCCGCTGTCGCCGCGGCGGGGCGGGGAGCGAGAGTGGGCCGCGGAGGCCGGCCTTCGGGCTCCATGGACGGGCGCCG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "SP1", "true_labels": ["SP1"]} |
449 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GTGCAGTGGTACAATCATAGCTGACTGTATCCTCAACCTCCCAGGCCCAAGAGATCCTCCCACCTCATTCTCATGAGTAGCTGGGACTTGAGGCACATGC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
450 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GCAACGCCACGTCGCACAAACAGGACAGGAGGGGGCGAGGGGTGTGTGCGCGCGCGTGCTGTCCCCAAATGGATGAGAAATAAGGGAAAGGAGGGGTTGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
451 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the GABPA transcription factor? TAACTCTCGTGGGCTTGCCCTGAGTCTCGCGAGTGCCAGCATTGCCCCGCCCTTGGATGGGCTCCTGCTTTCCAGCGTCTCACCGTCCCACTGTCCTACC | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "GABPA", "true_labels": ["ZBTB33"]} |
452 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GACTCCCCGTTTTCCGGATGCTCGGGAACAGTAGTCTTTGAACTGAGGTTTCCCGGGGATGTGCGGGGGGGGGACTTGGAGGAGATAAAGGTACGCAGGG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
453 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GGAAGGCCTGCACTAACGGGATCCGGTGTAAATAATTCTGAGCAGCTCCAGGTCCTGAGCCCAGCAAGCACGTGCTGCGGCAGGGCGCGGGGAGGGCGC... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
454 | 5_tfbs | Hypothesis: The transcription factor RELA binds to the following Human DNA sequence. Is this true? AGTGGCGCGGTCTTGGCTCCTGGGATTACAGGCGTCCGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAAACGGGGTTTCCCCATGTTGGTCAGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "RELA", "true_labels": ["RELA", "REST", "MEF2A"]} |
455 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? CCCGCAGGCGGTGCGGCCGCCTTGGGAAAGGTCTCTGCAAGGCGGGGGACTTCATTCGCGGCTTCAACCGCGGTAGATAAGCAAAGGTCAGCCCCGACCC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
456 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CCGGACTCCTAGGGGAATGTCTCCATTTGCTCTTGTTGAAGGAAGAAGGGCGAGAATTTCCAGGTCTGTGGAGACCCCACATCCCAGGTACAGAATTGC... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains TEAD4, No CTCF"} |
457 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the FOXA1 transcription factor? AGCCTTTCTAACTGATCTGGCTGCTATGTGGTCCAACCGTGTTTAAACAGAAAGTGCAAGGTAAACAAGATTTTTGTGGTTTCACTTTGATGGAGGAGTA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "FOXA1", "true_labels": ["GABPA", "FOXA1"]} |
458 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GCCCTAAAGGCCAAGAATGTCACATGAATCAGTCCCCCTATGACAAGCACTCACTTAGGCTGAGAAGTAGAGGTGAATGAGACACAGGCAGGCTCAGTTG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
459 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TTGAAGTAAAGGACGCGAGGCGGCGCTGTCACCGCATTCTGTGAACCGCAGCGCTCTGGGTCCCTCCCGCTGGTCTAGTATCATTTCAGTGAACGTCACT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
460 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: CACGAAAGACACACTTCACAGTCTCCGTGACCTCTGCAGCCCGGTGAGGCTTTGTTATGTAGATGCTCTTAATTGGGTGAGTCACTTACTGCAAACAGCT. Is this a CTCF binding site? | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "CTCF", "true_labels": ["CTCF"]} |
461 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CACCGTCCACATTATGACACGCAGCATACAGAGCCTCTGCAACAGCGTAGGTACTCCTTAATCGCAGTGTGGCGATGACACGAAGCCAGCACTCTCCGGG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
462 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? ACCCTCGGGGACTGCTGGCTGCGCAGCGTGGCCAGCCGGACCGCCCTACTGCGCACCGGGGCTGCCGGGGCGCCACGTGGTGCGCACGTGGTCCGGCCCC | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
463 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for E2F1?
Sequence: GTTCTCCCTGGTGCCGTCTCCGGCTTGGCGCCGCATCCTCCTCTGGGCTCGCGATGGCCGCGTCCCCTCCCGCTGCGGACGGGTCCTTTGGTACATGCAG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "E2F1", "true_labels": ["ZBTB33", "CTCF", "E2F1"]} |
464 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? TGTCTGCTCCTTACTGTACACTTGGCTGGCAGAGAAGGGAAAATGGAGCCGCCATCTTAACGTGTCTGGTTCCTAGTTTCTGCCGGCATTCACCCGTGCA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
465 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? AAGGAGCTCCCCTTGGAGTTGCCTGTGAGGCCTCCACACCCTCATCACTGACAACCTCTGGGGGGCGCCTGTCCTCACCACCTGTCACTGTCTCATCCAA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
466 | 5_tfbs | Can you confirm the presence of a JUN TFBS in this Human DNAsequence? TTGACCTATTTATAATCTGCGCCTTATTCTCCGCCCCCAAAGGCTGCTGGCAACCAATTCTCGGTGGCGAAGTCGTGACGTCAGCTGTTGCGGGTCAGAT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "JUN", "true_labels": ["JUN", "MEF2A", "SP1"]} |
467 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? GCGTGGCAGCGCGGAGGGGGACAGGCCCCGCGGGCCCCTGGTGGCTCCCGCCGGAGGAGCTGGCCAGGAGTATGGGGCTGGATGAGCGACCGTCGGAGGG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
468 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TCCTTGTTTGCAGAGTCTAGTGGGGCTGGCCCTGGTAACCTCTGGTGATTCATCCAGCACACCCTATGACCACATCCCCATTGTGTGTGTGTAGAGAGG... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
469 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the GABPA binding profile? GCGCCGTGCAGTGAGAGCACGCCGCTTGACCGAAGGGGCGGGGCCTGAAGGCTGAGCGCAGTCGCGAGGCTGTAGTTGGCAGGAGAGCGGGCGGGGCCTG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "GABPA", "true_labels": ["SP1", "EGR1"]} |
470 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? CGCCCATGCAAGTAGCTGGGCCTCGGGAGGGGGCTGGAGGGAGAGGGGAACGCCCCCCCGGCCCCCGCGAGAGCTGCCACGCCCTTGGGGATGTGGCCGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
471 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CCTCCCGAAGTACTGGGATTGCGGGTGTGAGCCGCTGTGCCTGGCTGCACTTTTCCTTCTAATGGAATGTAAGCGCCACTTTTGTCTGTTATTTTCACT... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains TEAD4, No CTCF"} |
472 | 5_tfbs | Could you verify if the motif for SP1 is present in this specific Human DNA sequence? GGAACCAAGATGGCGGCAGAAAGACCGAGCGAGAGCGTGACCCACGCCTGTTGCAGAAGGAAGCCTGGAGCGGAGGGGGTGGGACTAGGATCCGATTCCG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "SP1", "true_labels": ["YY1"]} |
473 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? CAGCGTGACGGAGGGGTGACTCAGACTGGCTGTGCAGTGTGCGATCCCCGGATCTGGCCCTCCACTGCCTTCAGGTGTGCACCGCGTCAGAGGAGTCACC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
474 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TTGGCTGGGTCCTGCGTGCGGCCCTGGATTCAGGGGCCTTCCAGAGGTGCGCATGTGCGAGAGTGGGCGGCGCGGCCTGGGCGGGGGTCGGGAGAGGGA... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
475 | 5_tfbs | Is the provided Human DNA sequence a target for the ZBTB33 protein? CCAGCTTTAGCGCGGAGGCTACCCTCTTCTATTTGCTCTTGGGCGTCAGAGCGGCACCCTACTCTGTGTAAGCCTTTGGATCCCGCTCGCACTTCCTCCC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "ZBTB33", "true_labels": ["GABPA"]} |
476 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TGTGTGCGTGGTGGTAAAGTGTGCAAGTGTGTGTGTGTTGTGGTGGGTTGGTCATGTGCTGTCGTGGCTGCAGCGTGTTGCGCATGTGGGCGGGTGTGGT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
477 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TGGCTCCATTTGAAATGGTTTTTTAGGCAAAGGAGACTAGATGAACGTGGAGGAGAGGGAAAGTATTTAGGCGCGAAGATGCTACAGAACAGGCTTATT... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
478 | 5_tfbs | I need to know if TEAD4 is likely to bind to this DNA fragment: CACATGCTGTGACCCACAGTAACCTTCATGGGCCAGGGAAGGGAGCATTCAGGGAAGACCCGCTGGAATGTGAATGGAGCAGGGCTTCCACCCACACCCT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "TEAD4", "true_labels": ["TEAD4", "EGR1", "STAT1"]} |
479 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CCTTCGTGGGCGGCCCCGACCGCCGCGGCTCGAGGAGGGGCGGGGCTGGGGCGGCCGAGCTCTCGCGAGGTTTCGTCGGGGGCTGGCGGCTGCGGCTCGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
480 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? AAGGGCGCTGGCCGCGCGTGAGAACCGGCGCGGGCGAGCCGGGGGCGGGGAGGCGCCGGGAGCAGGTGGTGCAGCCCGAGGTGTGCGGGAGGGGCTGGC... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
481 | 5_tfbs | Is the provided Human DNA sequence a target for the SRF protein? CCATGGCAACACCAGGAAGTTACCTTGTATGGCTTAACAAGGGGAGGAATCCTCAGTCCTGGGAATTGCCCACTCCTTTCCTGGAAAGCTTATGAATAAT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "SRF", "true_labels": ["GABPA", "SRF", "SP1", "STAT1"]} |
482 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GCTCCTGGGGACCGCGACACGCGCTCCCACGGCGGCTCGCGACCCACAGCCCGCCCGCGAGCTCGCCCAGAGTATCACGAGACGAGGGGAGACCTCCCCC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
483 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CACAGCAGCTGATATCACATTAATTTATACTTCCTCTCAGAGCTGACTCATTTCCGTTATTCTCTGGGACTCCCTTCTAAAATGTTTCCATCAAATTTT... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
484 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for SP1?
Sequence: GCCCAGGCTCCCCCGCCCTTCCCTCGGGGCTCCCCGCTCTCTCCCCCGCCACCCTCCGCTCCCCCCTTTACCCCGAGGCGTGCAGCCACTTCTGTGAAGA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "SP1", "true_labels": ["SP1", "EGR1"]} |
485 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GGGAAGGATGTAAATTCATTGCAAATGGTAATTTAATGGAGCCTAGCTTTTTTGTCATGCAAAAAGATCCGAATGGATGTGGCAGCCAGCAGCAATTCCT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
486 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? ATCTCGGCTCACTGCAAGCTCCGCCTCCCAGGTTCGCGCCATTCTCCTGTCTCAGCCTGGCACTGTGACATTTTATCTTGTGTTTACATTATTTATGAAA | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
487 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: ATAAATAGGCAGTGAAGTACAGAAACAGCTGGCTGGATTGGTTACAGGTGGGCGTTTGCCTTATTTGAACACAGTTTGAACACTCAGCAGTGTATGAGTG. Is this a SRF binding site? | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "SRF", "true_labels": ["SRF", "EGR1"]} |
488 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? AGCACAGATACAGGAACGAGCTTTATTAGCGTTAATTGCAATGAGTCTGCGCAGCTCAAAGGCCGGATTCTTGCTCACGGCGAAATCTAGCAGTGATGAT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
489 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CTATGGAATGTATCCCTTTAAAAAGCAGCAATAAACTTCTAGCCTATTTTGACGTTCTTAGAACACCTTAGTCACTTTCAGTTCCTCTCTTGTTTCTAC... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains TEAD4, No CTCF"} |
490 | 5_tfbs | Could you verify if the motif for ZBTB33 is present in this specific Human DNA sequence? TGCCAGGACCGGGAAGTTACTAGGCTCGCCCGCGGGAGTCGCTGTCCGAGCTTGGCAGTGCTGAAACCGCCGGCGTGAGCTAGGGAGCTGCGGGCTGCGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "ZBTB33", "true_labels": ["ZBTB33"]} |
491 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GATCATGGCCATGATTAAGAATTCAAATCAGGAATCTTCTCCAAAAACATAGGAAGAATCTGAGGTGATTTATCTGTCGTAATCCACTAGGAGATCGTAG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
492 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? ACAATCTCATGCACCCACCTCTTTCACGACGGTTCCTCAGCCTGTAGAGAAGGGGGCGCTGCAGTCATTTCCATGGCATGGGTGGACAGGTTGCATTAAT | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
493 | 5_tfbs | Is the provided Human DNA sequence a target for the RELA protein? AGAAGTCCAATGATTAATTACTTCCCACTACACATGCCTTATCTGCCCAGGCCAGGTCTGAGCTGTGTGCCTTTCTTGATCACCGGGTCTGTCTCCAGGG | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "RELA", "true_labels": ["GATA2"]} |
494 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GAGTCGAGGCGGTCTTGGCGGTTGTTGGACGAGGAAGGTAACTGAGAATTGAGGTTGGGGAGAGCCCTCCCGACAAGACCGGTCCTCGCGCTGGGGTTGG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
495 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GGTCCGCGCAGGCGCGCCGAGGACGCCAGGGCGGCGCATGAGTGCTGTGCCCGTCCACCTCGGGAACTACCGAGAAGATGGTGGCTGAGCCAGGAGAGG... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
496 | 5_tfbs | I need to know if RELA is likely to bind to this DNA fragment: CTGACACAATGATGCTCGACAAAGTCGCTGGCCACAGTGCTGAATCAAGACAGCCATATTGGTCCCTGCTAAATCTGACTGAAAACTGTACAGTACACAG | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "RELA", "true_labels": ["REST", "YY1"]} |
497 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CGTTTCTGAATGAATCCAGACTGATGTCACAAAGACGGCATATGGTACTCATGATTGACTGTCGCAGAAAACAATTACATCCTGTCGTGCTGTTCAATTT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
498 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GTGATGTGAAAAGCACCCTTTGTTATTTGTAGCTCAGAACTGGAGAGTTCCTGCATCTTGTGGCTTTCTGAATCGCTGCACTCAGACAAGAAGAAGCACC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
499 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the E2F1 binding profile? ACCATGCTTCATTGGTGTCTGGGTTGTGGTTTAGGGCTGATGCTGACCTGCTTGGCCCAGTAGGTGGCGCCAGTGACCCATGCTAGCCACAGCTCCTGGT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "E2F1", "true_labels": ["CTCF", "E2F1"]} |
500 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? ATCCCTAACTTGCATGCTCTGCTCGCTCCTCAGAGCCGAGGAGTCTCGCGGGCTGGCTCAATCCGTTAGTTAGTCCGCTGGACGGCACGACACCGAGGCT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
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