id int64 | subtask string | question string | options list | answer_index int64 | answer_text string | metadata string |
|---|---|---|---|---|---|---|
201 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CACCGCTTTCAAGGCATCATGCCCAAGTCGCCACTTGGGGGCAGTCTAATGCCTCTGTCCCTTCCCATCGCCATTTTCCCGCCTGCCTTCTCTCTTAGG... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
202 | 5_tfbs | Hypothesis: The transcription factor ZBTB33 binds to the following Human DNA sequence. Is this true? CACAAGATCCCGCTAAGAGGAGCTCGTGAGAATCAGGAAGAGCCCCATCCTCATTCAGTGTTCCTCCAGCGCCCTCTGCTGACAAGGTTTAACACTGAGC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "ZBTB33", "true_labels": ["ZBTB33", "CTCF", "GABPA"]} |
203 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TCTATGCACTTGTGACCTGGCTGGTGATTTGGGGAGGGGGCCGCTGCCAAGTGCTCACCACCATTTGGAAGATCTGCGTGGGAATCAGTGTTTAAGTTGG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
204 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GAGATGATTTTGCCCCAGGGGACATCTGGCCATATCTGGAAACACTTGTGGTTGCCACAACTGGGAGGGGGTGTTACTAGCATCCAGTGGGCGAGGGGA... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
205 | 5_tfbs | Can you confirm the presence of a STAT1 TFBS in this Human DNAsequence? GGAAGCTAGGCTCAGGGAAGAATGGAGTTGCCTGGGACCAACCTTCTGGTAAGAGACAGCCCCGGGCTGGGACACAAGCTTCCTGACTGCTGTTATCTTC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "STAT1", "true_labels": ["STAT1"]} |
206 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GGGCGGGCGCCGAGCGCTGAGCGCTGAGGTGAGGCGAGGCGAGGCGAAGCGGGGGCGCCCGGGAGCGCGGGGCCAGGAGGGCAGAGGGAGATGCGGCCGC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
207 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GTGGGGGGAGGGAGAGGAGACGCAGCCTGGTGGAGATGAGGCTGAGTGGGTGGGAGAGGGAGAGGGAGTGAGGGAGGATTTCCGGGATTGTCCGAGCTGA | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
208 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the ZBTB33 binding profile? AAGGAAACAGACCTTCTGAGAATGAACTTCCAGTGGATCATTCCTTTTTTTATCAAAACATCTTAGCAGAGCTAAAAGATAGTCTAGCTGGTTTGGGAGG | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "ZBTB33", "true_labels": ["STAT1"]} |
209 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? AGCGGCGGAGGTCAGCAGCGAGGGGGCAGGGCCGGCGCTGGCGGCCACGGAGCTTGCGCGTCGCTGGGCTCGGAACCCAGGGACGCGAGCCAGCGCTGGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
210 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GCCCTCCCGCCCCCAGCACGGCCACCCGTCACCGGCGGCCAATCTAACGTAACTTCGCGAGATCCGGACTGGGAGGCGCCCTTCGACCAGTGCGCATGCG | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
211 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the YY1 transcription factor? GGAGCAAATGTTCAAGCACAGAGCCATGCACACTAGGCCACGAACTTCCCGTCACACATGCTCTGGAGGAAGAGGAAATGCTTGACGCATCATCGCTCAG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "YY1", "true_labels": ["GABPA"]} |
212 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CTACTCTCCTTTTACTCTGTCCCTGTCTCATAGCTGTATGTTAAGCGACTTCCTGTAGACTGTTCTCAGTGTTATTTACTGTAGCTTCCTGCCAGGCAGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
213 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GAGGTTCAGACAGCGGAGGTGAGCTCAGCCAGAAGTGTGAGGAGACAGCGCCCTCCAGTGGCCTCTGCGCAGCAGCGAGGGAAGCCGAAGGAGGGGGTG... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
214 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the E2F1 transcription factor? TGACTTAAGATAACAAAGCCAAGCTTTGTGCTTAGCTGTTTTTGACTGACATCATCAATTTTATTTTATGTTGGTCACCTCCGGTAACAGGAAAAAATGG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "E2F1", "true_labels": ["JUN"]} |
215 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GAGTTTTACAATTTCCACACACTAGATGGCACCAGAGACAATTACATAACCACCTGTTTAGTAAACAAGTTTATATCCTGAAAAATCCCCTAATTTTTCA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
216 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? AGGCGAGTCGCCGGGGGTCGGCAGAGGTCAGCAGCCTGCGAGACCCTCCTAGGCTCGTGGCCCTAGGCGCGGCAGCTGACACGTAAGTCTCGTCGCCCGA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
217 | 5_tfbs | I need to know if TEAD4 is likely to bind to this DNA fragment: TGAGGGTCTACGGCTTCCTGAGAGGAGGTGCTGACTCACTTCCTTTCCCTCCCGGTGCTCCCTGGTCTCTGTGTCCTCAGCAGTTCCGTGGGGCCAGCCA | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "TEAD4", "true_labels": ["GABPA"]} |
218 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? AGAATCATCACATTCCCCTATCTTGCCTGGCCCCAGGCTGTGGAGCAAAGGCCGCCCTTGCGCAAGGCCCGTGTGCGCCCAGCTGTCCTTGCGGTGGCCC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
219 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GCACCGGGGACACCAAAAAGCAGCCCAAGCTCCAGCCGCCATCTCCTGGTAAGTGGCGGCGCTGCAGTCACTGGCCCAGGAAAGCCCAGGCGCCTGGCCT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
220 | 5_tfbs | Is the provided Human DNA sequence a target for the GABPA protein? AGCTTTTGGGCTGAGATGATGGGACTTTCCAAATATAGAATCATGTCATCTGCAAACAAAGACAATTTTACTTCCTCTCTTCCTCTTTGAATATGCTTTA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "GABPA", "true_labels": ["RELA", "GABPA", "SRF", "MEF2A"]} |
221 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CCACCAGCACCATGCAGTTCCAGGAACACCCATATTTGGTGTAGAAATGGGTGGCACTACAGTTCTGAGAAATCGTAACTGTTTTCCTGGAATCTTCCTG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
222 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GGTGAATCTCAGAGGCTCTGGTCACCTGATCATAGAACGGTTTGCCTTAGTCTGGACACTAGGGGGCGCTTGGGGACCATTTCTGAGAAGACTTGGGGTA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
223 | 5_tfbs | I need to know if GATA2 is likely to bind to this DNA fragment: CCTATCTTCCAGGTCCAGAAACTGAGGCTCAGAGGGAGACTTTCTGATGAGTGCAGCGTGCAGATAAGAGCATCTCCAAAGCTACCTCCTTCCCCAGTCA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "GATA2", "true_labels": ["GATA2"]} |
224 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? AGGGACGAGCACCAACCACACCAACCGCGAACGGCTGGGTCGCCGCTGTAAACGGGAGGCCTGCCCGCCCAAAGCTCGCAACCATACAGCGCCGCGAGCG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
225 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TGGCTTCCCGCGCTGCCCTGCCCGGGGCTGGTCTCGTCCCAGGACCCTGGAGAGCGGCCCCAGGAGGCGTGGAGGAGGGGAGAGAGCCGAGGGAAGTGG... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
226 | 5_tfbs | I need to know if GATA2 is likely to bind to this DNA fragment: TCGGCACAAGATACAGGTCACAAAGACCTTGCTGATAAAAGAGGTTCCGATAAAGAAGCCGGCCAAAACCCACCAAAACCAAGATGGCAACGACAGTGAC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "GATA2", "true_labels": ["YY1"]} |
227 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CGTTATGAAAACACCTTGGCTGTGGGATGCCTGAGTCAAAGCCACCTAAATAGGCCTCCAAGTGGACGGATCAACTGCACCCAATGAGAAGGTAGGTCAG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
228 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CAACCACCTGGAATTGAGGCTGTTTCAAGGTACAGATGCAGTGTGTGTTTGTCTTGCTTTTGTTTGCACCTTCTACCAGCTGGAAGCCAGAAGGTGTGGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
229 | 5_tfbs | I need to know if YY1 is likely to bind to this DNA fragment: CCGCCTCTCTCCCACCTGACTGGCTCCTCCCTTTCCCCGGCCGGACACGGCGCCCGTCGCAGCTGCCAGACTCCAAAATGGCAGCCGCGCAGAGCGCGCA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "YY1", "true_labels": ["YY1"]} |
230 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CCGCTTTTGCTTCATACACTAGAGCTAGCCCGCCCCTGCGCTTTGTAGGGACGCCCGCGCGGCGAAGAAATTGCGCAGCGACCGGCAGCGAGCTGGTCGT | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
231 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TGCATTATGCAATGACTAGACGTTACCACTGGATGGTGCATTCTTTACCTGTAAGAAATACACATTGGGGCCAGCACGGTGGCTCACGCCTGTCATCCC... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
232 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for TEAD4?
Sequence: GTGTATAGAGATGGAAGGGCAGCGTGGGTGTATCCACAGATGGGTTTAGGTTTTTTTTTTGGATGTTTTCTATTACCTCATTCAGCAACTTTATGTTTCA | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "TEAD4", "true_labels": ["JUN", "EGR1"]} |
233 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GAAAAGAATTTTAGATATCGGGATCGCATCCTTCAGTAAGGCAGGAGAGCCACATTTAAACGTCCCCTGCAACATGCCTAAAAAGACATCTTTCAATCTG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
234 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? ACGGCCAGAATGATTTCCTTCAAAAACAGCAATACGATGATGTCATTTGGCCGTTTAAAACTTCCTGTGGCTTCACGTTAGTCAGAGTCTAAACAGGAAA | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
235 | 5_tfbs | Can you confirm the presence of a FOXA1 TFBS in this Human DNAsequence? AGGCTCCACAGCCCTCCCCCTCCCCAGTAAACAGCAACAACCGTGCTGATGGCGGGACTTGGCACGAGCTCCCCGCCAAGCATTATCAGACACCCCAGAC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "FOXA1", "true_labels": ["FOXA1", "SP1"]} |
236 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GCCAACTCCCCCCCCGCGAAGCACTGAGCCCAGACCACATCAGCGCAGCGGTCGCTGCGCGCCGAGCCGCCACGCGCCACGCCAGTACCCACGCGGCCGC | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
237 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? AGCCAGTGTCAGGACAAGGGCCTCTCTTGGGGACAGTGGCCTCTTTTCATGGGAAAGCCCCAGGAAGTGACGTGACCTCTTCAGGCTCCATGCCTGAGCC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
238 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the REST transcription factor? ATCTTCCCTTAACAGCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGGCAAATCCAGGAAACAGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "REST", "true_labels": ["REST"]} |
239 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? CCTGAGGACTACCAGTCCCAGTGTGCACTGCTTCTTCCCCGGCTCTCCCGCGAGCCGACTCGGAGCCGTGTCTCTCGCTTCTACCCGGGGTAGGCGCGCT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
240 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CGGCTCCTCCCGGTCGCCGCCACCGCCTCCATGCCGGATCACGTGACTCTTCCGCCCCGCCCCCTTCCCCTGCCTCCTACTCCGCCCTTCTCTCTCCTCT | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
241 | 5_tfbs | Hypothesis: The transcription factor SRF binds to the following Human DNA sequence. Is this true? GGATTCCCTTTCTCACTCTAGCGAGGAGGACTTGCACACGTTCTGGAACACTTCCCCAAATATGGTCCGAGGAAAGAAGTCCCTAGTGCCATCCCACCCC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "SRF", "true_labels": ["SRF"]} |
242 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? TGTTAGGGCTTCTCACACTGAGCAGAGTTCAGAGCAGACTTCTCTGCTCAATGATTGCCTTCGGGTGTGTGTAGCAACCAGGAATATAGGGGGTCCTGAC | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
243 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TCCTCACTCAGCCCTCGGCGACCCTCTGGTACCCTGGACAGCTCCCCGGGGAGCAGTCTACCGCTAGGCGGCGGCTGCTAAGAGAGGAACCCTCCTGACG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
244 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the POU5F1 binding profile? CATACAGAAGCAGGTGGTGGGTTTGCAGGATGCTTGAATGACAAAGGTTTCACAGCAAATGCAAATGAGGGAGCTAGCAGTCTCTGAAAATCAGATTAAA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "POU5F1", "true_labels": ["POU5F1"]} |
245 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? TCCTCTAGCATTTGCCCTGTGCTGCGCATGTGCTCGCCCTGCAACCACCTTTGGGGCAGGTACTATCGTATCATATCGTATCATCATTGGCTCAGGGTAT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
246 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CTCTCTCTCTCTCTTTCTTTCTTCTTTTTTGAGACAGAGTTTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCGCCATCTCAGCTCACTGCAACCTCCC... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
247 | 5_tfbs | Could you verify if the motif for TEAD4 is present in this specific Human DNA sequence? GAATTCACCCAGCCTTGTTCCATTTTCTCTTAACAAAACACACCGCAAAAGCTCTCACAAGCTGCTTTGATGAAGCCACATGTATTTCCCCCTTCACAAT | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "TEAD4", "true_labels": ["MAX"]} |
248 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? TGCCGTCCAGGGTGCTGAAATCTGGTCTCAGAACCATGCACAAATAGATACAAAAATTCAGAAGACAATGCAATGCTTGGAAACCCGGCTAAAGCTTGTG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
249 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TGTCCGCGCTCCTGGCCCTCGTCCTTCGCGCCAGAGCAGGTTCGCAAACTCCTCAGACCCTTCTGCTCCCGGCCGCCGCTTTCCGCCGGGGCGAGACCCC | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
250 | 5_tfbs | Is the provided Human DNA sequence a target for the YY1 protein? TGCCAATCACTGCTGGTTTGCCCTCCCCCTGGTGTTGGCCCGGCTGACTCGGGGTAGGGGAGGTCGGGGAGGGGGCGATAAAATGGCGCAGGGGGCGGAG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "YY1", "true_labels": ["REST", "YY1", "CTCF", "SP1", "NRF1"]} |
251 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? TCTTCTCCACTTCGGGAAGCCAGGCGCAGTCCACTCACCATTCCTCGGCTTCCCGGGTGTCCTGGCGTCAGCTAGGGATGTCCCAATACTCGCAGGTCAC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
252 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CCACGGAAAAGAGGGCCAACTTCCGCTTAGCGCAGGTCACATAGGCGCTTTCAGTTCTCGCGAGATGAGCAGAAGTACGGGATAGCGGAAGTGAGCATG... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
253 | 5_tfbs | Can you confirm the presence of a RELA TFBS in this Human DNAsequence? GTGTTACGCTCTGGCAGGGGGGGTGGGAGTCATGATCAGGGGTGTGGGAGGAAAATCAGGATCAGGCCATGACTCAGAATGCTAAGAACTTTGATGGAGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "RELA", "true_labels": ["RELA", "EGR1"]} |
254 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TGCACACTGTGGCTCGGGCGGCAATGCGGCAATCTGGGAGGGCTGCGGCCGTCAACGCCCACGCAGCAGGGAGAGACCGGGAGTGGACAGCCACAGGCAG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
255 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CGCCCCCTCGTGGTACTGAGGGCACTCTGATATCCTGAGCACCCCTGATGCTTCTGAGCGCCCCCAGGTGTCCTGAGCGCCCCCTGGTGGTTCTGAGAG... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
256 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for SRF?
Sequence: CACGGGAACTCCCATTTATAAAACCATCAGATCTCGCGAGACTTATTCACTGCCACGAGAATGGCATGAGTGAAACAGCCACCAAGATTCAATTATCTCC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "SRF", "true_labels": ["ZBTB33", "RELA"]} |
257 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GGGCTTTTAGGGAAAACGGTGTTGGAGATGGCTGGTGGCGCAATACCTACCTTCCACCACTAGATGACAAACTTGCAACAGCGTGCTTCCAACAGGACGC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
258 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TGATGTTCAGGGAGATGGTCAGCAGATGGTGCTAACTTACCACCCTTCCCTCTGAATCCTTTGGGGGCATTCTTAAAATTAATCCAGTGGAACTTTCAG... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
259 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: ATCGGCCAGGAATGTGTGAGGGGGAAGGGGGAAGGACAAGAGGTTTCACCCCCTGGTTAGTTTGGCCTCGCTAAGGCAGGGAGCCGCCCTCACGCAATGA. Is this a TEAD4 binding site? | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "TEAD4", "true_labels": ["TEAD4"]} |
260 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GTCAGCTAAAGCCCTGAGGGATGGTCATACTGAGTCAGTCGGACCTTTGGCTCTCGGCACTCACTAGAGCACCTGTATTGACAGGATTGTTCATATGGTG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
261 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TATTCACAAGGTGCAAACACTTACATGTGTATATGCATGATTTCACCACCAGGGGGCATTGTGGTTTGACTGTCCAGTTAAAGAGCCTGTGTTCTATCAG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
262 | 5_tfbs | Is YY1 occupancy expected at this locus based on the Human DNA sequence provided below? TGAGCGCAGCCCGCGCAGCTGGCGAGGGAGGGGGCGCCCGCGCCGCCATATTCCCTCCCGCCGGCCGGCTCCGCGGCGCGCAGCCACCATGAGCACCGCC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "YY1", "true_labels": ["NRF1", "EGR1", "YY1"]} |
263 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GTCCTCCCCCGGGCGCTCGTGGGCTTCCCTGAGGGCCCAGCTCTCACTCCGCCCCTTCCTGCCCGCGCGTGAGTCGCCAGAGGGGGCCCGCCCGGTCCTT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
264 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? TCACGCTTCCGTTCACCCCTCCCCTCCCCTGGGGCGGGTCAAGTGAGCCGGGCGGCGGGGCGGTGCGGGCTGGGGGAGGGGAACAGGAAAGGCCTGGCGG | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
265 | 5_tfbs | Hypothesis: The transcription factor NRF1 binds to the following Human DNA sequence. Is this true? CAGCAGGCGCTGCTTTAGTTACCAGCACTTTGCTTCCTCCGTCTCCCCGCGCCAGGCATCGGGCATCCCAACCTCGACTTTGGCCTTCAACTTGGCGCGC | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "NRF1", "true_labels": ["RELA", "SP1"]} |
266 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? TCTCATCTCTTTGTTTCTCCCCGGCTGCCGTCAGTCACCGGCTCTCTGCGCCCCCACCCGCGCGGGCTCGCGGCCGTGCTGCGGGCGTGGCCTCAGCCGC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
267 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TCCTCGAGGGAGCTTTGGCCAATTTAGGGCAAAGCGGAACTGTGTTTGGTAGTAACCTCGGGCTTGGGTTTCTGTGTCACTCAGCATACGTGGAATGTT... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains TEAD4, No CTCF"} |
268 | 5_tfbs | I need to know if NRF1 is likely to bind to this DNA fragment: CCCAGAACGCCTTGGGACGCGCAGTTTGGACAGAAGCAGCCATGACGTGCCAGGCGGCCTGTGCAACCAGTCTCCATGGTGCTGGAGTGGGGGTGGGGGA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "NRF1", "true_labels": ["REST", "SP1", "EGR1"]} |
269 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? ACGGGGCCCCGCCCCGCCGCCTCTCAACCATCAGGTTCGGCAGCCCGCGGCGCCGCCTGGCAGCTCCTCCTCTTCTCCGCCCCGCCGGCCGCGGGCGCGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
270 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CGGTTCCTTGGTTCCTGAGGGCGATGGCGCGGGGTGGCTGGCGCCGGCTACGCCGCCTGTTATCCGCGGGGCAGCTTCTATTCCAGGGCCGCGCGCTGCT | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
271 | 5_tfbs | Hypothesis: The transcription factor YY1 binds to the following Human DNA sequence. Is this true? AACCCATGGGGGTGAGGTGGCCATGCTGTCTGTCATCAGCCCACCCACCCCTAATTGCTCCTCCTCCACCTGGTTCCATGGGGAAAGAGGGTGGGAAGGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "YY1", "true_labels": ["EGR1", "YY1"]} |
272 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? ACAATACACACATAACACACACATACAACACACACACGCAACATACACATACATACATATACACATACAAACACACACAACATATAATACAACAATACAC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
273 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TGAACGGCAGTTTGGGAGTCGGACCGGGGCCTGTGGATTAGGATGCAGCCTGCTTCCCGCCCAGCCGGCTCGGCCAGGCCAGCGCCCGCCCCTCCCTCC... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
274 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: GGTCAATTCCGGGAAGTGATTTTGGTTCCTAGAAAAACCCACATGGCTCCTGGCCCAGCCCAAGCCCTGCCCAATTGTGCAGCCCAGACAGGGAGCCCTC. Is this a STAT1 binding site? | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "STAT1", "true_labels": ["STAT1"]} |
275 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? AGCTGGGGGGAAAACAGCGTGAGTTGGATAAGTGGAGCTGAGCGTGGATGCACAAAGTGCACTGAGCCATCATTCCTGGAGGAAAACCATTGAACAAATC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
276 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TATCTCATTGCTACAAAGAGTCTGTTTTGTTAGTCTATGATCTCTATTTTAATGTTAATGCTGGTCAGTTGTGCCTAAATTCCAAAGGGAGGAGGGAAC... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains TEAD4, No CTCF"} |
277 | 5_tfbs | Could you verify if the motif for POU5F1 is present in this specific Human DNA sequence? ACATGCAAAGCACTTTAGACTATATTTAGTACCTAATTGATGTGGCAGCAGGGGCCGCCTGGGATGTTGTGGCATCATTTTTGCTCTCAATGAGACACGA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "POU5F1", "true_labels": ["JUN", "CTCF", "POU5F1", "MEF2A"]} |
278 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? TAGGGTCATGGAAATCGCTTCAGCCCGCCCAAGAATAGAAAGCCGAACAGTGGGGCCTTCAAGGAAAGAGGTGCTACGTGCACAAAAAGTGTTGCCTGTC | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
279 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TTTGCAACCTCAAAACACTTAGCAAACCTTGCATCTTGAGGGACTAAGTGGCTAAGTTGGCTGGACTTCCTGGGTCCCTAGGGACTTCCCTAAGGGGAT... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
280 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the FOXA1 transcription factor? AACCGCTCTTGCAGCCTGCGGTCAGCGACGACCCGGCACTCGGCAGCTCCCTGGAACGGGAGGGGCAAGCATACGGCCCGCTCCTCTGCTCGCGCCCCAG | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "FOXA1", "true_labels": ["SP1"]} |
281 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? AAAGCTGTAAATCTCATTTGGGAGCAAACACACACATTGCCTTTTGGGGCCCTGACCCATTGGAACTGTGTGGGTTGTAGCACAGCTGGACTGGGGTAGG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
282 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GCTGCCTGCCTCCCTCTAGCGGTCTAGCCTGAACCCATGCTCCTGCGCAGGAGAGCATAACCAGTTAATCAGCCAGTAAGCACACACTAAACATCTACTG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
283 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the SRF transcription factor? TTCTGCTCATTCTTCTATCACAGCTCCTCTGACATTTGCCAGACCTCACCATTTCCTCAGCCATTTCTGGTCTGAATCATCAGCCCCCCATGCCTGCTGC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "SRF", "true_labels": ["SRF"]} |
284 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? ACACGCGCCCCTAAAGGAGGGGAACGGAACGCCCAGGCCAATGCGGGAGCCCACACAAGGCGGACACGAAGGGTCGAAAGTGAACGTAACAAGTCCCGAT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
285 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CCCAGGAGCACGGGAAGCAAGAGGCGCCCCACGGGGGTGGAGCGCCGGCTCTCCTCCGCCAGCAGCCGCCGCAGGAACCTGCCACACATCCTGTTTTGGA | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
286 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the FOXA1 transcription factor? GAGCGGACTCCGTCGCCGTCCCGGCCCCACCGCCGCCCTTCTTCACCTTCATGGCCTTGCGGGGCCGAGGCTCGCCTGCTGCTGCCGCCGCTGCCTGCGC | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "FOXA1", "true_labels": ["SP1"]} |
287 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? GCCTCCCACTTCATTGCCCCCTCCCAGTTTTCAGCCCTTGGTTGAACCTGACTGGGCTGGGTGTCTCCTGTCAACTTCTCCCATCCTCAACACTAACACA | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
288 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? ACCCACAAAGGCCGGAAGCGGCCACGGGGGGTCTAAGAACCAGCCCGCGCGGGGCGCACTTCCGCGGCCGCTCTAGGAAGGGAGCGAAAGGGGCTTTCAA | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
289 | 5_tfbs | Could you verify if the motif for SP1 is present in this specific Human DNA sequence? AACACCATGTGATTTCTAAATACGATTAGTGACTGATATATATGGGTGTAATGCTGTTGTCATGGTTCATGTCTCCAGGCAAAATCTGCTGACTCACCTA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "SP1", "true_labels": ["MAX"]} |
290 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GGAGGCGGGGCCCGAGGCCAATACCGCCCAATCACAGGAGGGAGCTGCCCCAGGGTACCGCCCCGGGGGCCTGACTGGCCAATGGGAAAGTGAGCGGCGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
291 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GCCCCAGCCTCCGCTGGACCATCCCCACCGCCGCCCACACAGTGGGTGAAGCCTCATGTCTGGGCGGGTCCCTCCTATCATAGTGTGGGGCCCTAGCAGA | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
292 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for ZBTB33?
Sequence: GACAGGGCCACCACCAGCTCAAAGTTACAGAGGTCACCTGAGAATGGCTGGGGTCAGGGCATCCACAGCCTGAGTGGGCGGCAACCCCAGCTACTCTGCC | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "ZBTB33", "true_labels": ["EGR1"]} |
293 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GCTTCTACTGAGTCCCACCTAGTTCCGTGGTTTTCTCCCTGTTCCTGGCTCTGCCCTCTCTGCCCTACTCACCTCCCACCCACTTCCCTAAGCATTGAAG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
294 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GGAAAGGAAGGGAAGGATAAAGGGGAGGGAACAGGGAAGGAGAGGGGCGGGATGGGGTTGGATAGGGTGAGGAGGAAGGAGGGAGGAGGGATACGGTAG... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
295 | 5_tfbs | Is the provided Human DNA sequence a target for the MEF2A protein? AGGTCTCTACAAGAGCCTCTGAAACCTGAAGGACCACACACACACGCACCCACGCGCGCGCGCGCACACACACACACACACACACACATGCATAAACAGT | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "MEF2A", "true_labels": ["EGR1", "NRF1"]} |
296 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TGCCTAACATGTGTCTTTATGTCAACAGAATCGAGGCATGTTTACACTGTCTCATGAAACACTCTGCTTTACCCAGGGACAAAATATAATGTTTACCTAG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
297 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? AAACGGGTCCAGAAAAGTTCAATAATTGCACGTACCACATACCCACTAGGTGTCAGGGCTGGACATCGAGCCCAGGGCTAGCTCTAAAACCAGTGCTGT... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
298 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: CATGGCGGCGGCGGAAGTCTCATCAAGCCCGGCGGCCTTGTCTCTGGGCTGGGCCTTCTCGAGCTACTGGCCCTGCTAGCCCCAGTTGTGGGGTCTCAGC. Is this a GABPA binding site? | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "GABPA", "true_labels": ["EGR1"]} |
299 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? AGTAAGTCTCACGAGATCTGATGGTTTTGAAAAACGGGAGTCTCCTTGCAAAAGCTCTCTCTTCTCTTGAGTGCCTTTAATCTTCCACCATGACTTGTGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
300 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TTAAGAAACACTTTTAGAGCAATGCCCTGTGTCAAGCACTGCTCTACATTGAGAAAGTGGCTCAGAGCAGTCTGAGGAATGTGAGATATGCAAAATTGGT | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains TEAD4, No CTCF"} |
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