id int64 | subtask string | question string | options list | answer_index int64 | answer_text string | metadata string |
|---|---|---|---|---|---|---|
301 | 5_tfbs | I need to know if YY1 is likely to bind to this DNA fragment: AGTGGTACGGCTCGCAGGGGCGGGGCCCAGGTCATGTGACGCGGCCGCGGCCGCCATTTTGTTCTGCGGTGCTGGTATTTAGAGCGCAGCGGCTGACGGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "YY1", "true_labels": ["SP1", "YY1"]} |
302 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? AGACCCACAGTCACCACAAGGAGGGTGCCCGGCAGGGGGAGCTCCAGAAGGAAGGGAGCACTCTGGACCTCAGGACACCTCAGGACATGCAGTGATGGGA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
303 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TGACGTCAGTGGGAGCGGAGGCGATTTGGCCTAGAGCTGGGGCTGAGCACGTGGGATGGTCGGGGCCTGTTTGCCCAATGTACACGAGGCTGGAGAATA... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
304 | 5_tfbs | Could you verify if the motif for NR3C1 is present in this specific Human DNA sequence? GTCCATCTGTCCACCCGCCATCTACCCGTGTATCCACCCACCCACCACCCACACATCCATCCATCCATTCATCCCTGCAATCAGCAGGTCAGCCCCCATT | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "NR3C1", "true_labels": ["EGR1"]} |
305 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? AAAGTCTGCCTCCATGTCAGCTGAGTTTTGACCTAAACTCTGGAGAGTTCTAGAGTTGGTGGCGAGCCCACAGGACTTTGGTTTCAAGTCTGGATGCACA | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
306 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CTGCCTGGATGACAGAAGATCAGAGTGTGCTGGAATGTCCCACCCTTTCCAGCTTCCCGCAGCCAAGCCAGGCTCTGGGGTGATCATTCCCATAGCAACC | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains TEAD4, No CTCF"} |
307 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: GGGAAGAGCGGGGGAGACCGCTACTTATAAAACCATCAGATCCCATGAGAACTCACCCACTATCGCGAGAACAGCCTGAGGGAACACTATCAGGAGAACC. Is this a ZBTB33 binding site? | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "ZBTB33", "true_labels": ["ZBTB33"]} |
308 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TTCTTGCATCTGTTAGCATGCACTCTTAAGCGTTAGGAACAAGTTGGTCCTATTGGATGGGCAAAGAGCTTTTTGAATTATTAGTGTTAAAGACGAGAAA | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
309 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GGGACAGCGTGGGAGTTCATCAAGCACCTTAGAATATTGCACGATTTTAAACTTATGAATTGTTTATTTCTGGAATTTTTCATTTACTATTTTCAGACTG | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains TEAD4, No CTCF"} |
310 | 5_tfbs | Is the provided Human DNA sequence a target for the EGR1 protein? AGTCCAGCTGTAGTCACATTCTCACTTCTAAAGCAAGGGTAAAATCCTTAAGTAAACACGTTCCACAGGGGCTGTGCTAAAGTACATTTTTCAAAGACCA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "EGR1", "true_labels": ["FOXA1"]} |
311 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? AAGCGAGTAGCCATTGGTGAGGAGACCTGCAAGGCTAAAACATCATGCACTGGATGCCAATGTGGATCACGGTGCAAGTGGTTCAGGGTGGAGCACAAGT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
312 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GCCCAAGAGCCCGAGAGGAATCGGTGCTGCGCTGCTGGCGCGTCGCGTCGGGTCGCCTGGGGGAGTGGCGCCCAGGAAGGCAGCAAGCCGGGTGGCCGCA | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
313 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the CTCF binding profile? GCCAAGTACACAAGCTCTGGACTCAGATTTCACTTCCACCGTTTTAGCTTTATAGGTGTGACCTACACATGTGACTTCACCTCAGTTTTGTGATCCGTAA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "CTCF", "true_labels": ["MAX"]} |
314 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? TGTCTGGACTCACTCAGGCAGACAACAGGGCGTCTCGCAAGACGAGACTGGCTCATGCTGAGAACGCCCCCCTTCTTCCAAAGGAGTTCCTTGTTCTCCC | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
315 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CACAAAATGCCACGGCGTGACGCCCCATTCCGAGCGCGGTGCGGACGGCGGCGCAGGGAGCGCAGCGCGTGCGCCCGGGAAGCGCGCGGCTCTCAGCTCC | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
316 | 5_tfbs | Is POU5F1 occupancy expected at this locus based on the Human DNA sequence provided below? CTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCGCCCCCGCAAAAAAAAAATTAACATTTGTTAATTTTTTCTAGCTCCTTGGTGGTCTTGTTAAGATT | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "POU5F1", "true_labels": ["SP1", "EGR1"]} |
317 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? TGGCGCTGTCGTGTACCCTTAACAGGTATCTGCTCCTCATGGCGCAGGAGCATCTGGAGTTCCGCCTGCCGGTGAGTCCGTAGCGCCCTCCGGAACTTCC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
318 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CGCGCCCGGCAGCCCCGCCACCGTCAGCACCTGCGCCTCGGGCGGGCTTTCCCCACCTCTGGGAGGCACGAATCCTCAGGGGCTCCTCGAGAGGGCGCC... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
319 | 5_tfbs | Can you confirm the presence of a GABPA TFBS in this Human DNAsequence? AAACCTCGCGACACTCGCAACTCCCGAGGCCCTTCCTGCTACTGGCCTCAGAGGGAAGAGACATCGGGAAGATTGCTCCGCCCACAGAAAGGAAGATTTC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "GABPA", "true_labels": ["ZBTB33", "GABPA", "SP1", "EGR1"]} |
320 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? ATACAGTACTAACTTGCACCTCAAGACTTTGTCCAGGGTTTGGATGTGCCAGAAATGATGTTAATTGCTGTTAGAGTGACCATCAGTTAGTTCTTTGGAC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
321 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GGGCTGTAGTAGGCGTCCATGGCAGCGGCCGGCGACTCGCAGTAAGAGACGCAAGTCTCAGCATTCATGCCTGGCTTGCGCAGGCGGCGGGCGGGGACGC | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
322 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the RELA transcription factor? CCCTACACTAGTGATTTTCCTGAGAGCTGTCCAGCATGTGCCTGTGGTCCGGGCAGCATGCTGGCTCCCCCTCCCACCTTCCCTTTCCCAAGTCCTCCCA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "RELA", "true_labels": ["RELA", "MAX", "SP1"]} |
323 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? AAGTGGGCTCCCTCAGGCGCAAGATCACTAAGGAGGAGATCCATACATCCACCCCCCAGTGAGAGGAGCCTCTAAGGCAACAGTGAGATGAAAGAGTTTA | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
324 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CTCATGTTGAGACAGCCAAGCATAAAGAGACTCCCTACCGGCCTGCGCACTGGGCAGAGTGCACGCTGGGGTGGAGCCTCAGGAAGTTGGCGCCATTTT... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
325 | 5_tfbs | Is the provided Human DNA sequence a target for the ZBTB33 protein? GATGGGTTGGTTCCACATCTTTGCAATTGTGACTTGTACTGCCATCAAGTGTCTTTCTGGTATAATGACTTCTTTTCCTTTGGGTAGATACCCAGGAGTG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "ZBTB33", "true_labels": ["CTCF"]} |
326 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? GCCGCGGCCGGGGGCTGGGGCGCGGACTGGTCCCGGGAGCCCGACGGGCCTTGCGAGCAGCGGGCCGCGGGAGAAAGCAGCAGCCGCAAGGCGGCGGAGA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
327 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? AGCGCCCGCCCGCAGGGATCCCAACGACTGCTGTTCCCGCCTCCCGGTGAGACCCCGCAGTTGCCCTGCCCTCACCATGGTGCCGGCGGGGACCGGGCT... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
328 | 5_tfbs | Hypothesis: The transcription factor JUN binds to the following Human DNA sequence. Is this true? TTGGGCTGTTTTCACGTCTATATAAGGCAGTGCAGAGTGCTTCCTTTGATGTGTCCCGCCTCTGCTGTGGCCTCATCATGCCGGGCTAACTTGGTCTTCC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "JUN", "true_labels": ["JUN", "SRF"]} |
329 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CTCCTGGAGCACCCCGGGGGCCCGAATTGTTCATTCCGCCCAACTGCGTGCCACTCACGCGACCCCGGGGTTTGCCGAAAAGGAGCCTCCGGGTGGGGTG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
330 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CCGCCGCCGCCAGGTGCCCGCCGAGGGCCGGAGGGAGGAGCCGGGGCGGCGCGAGGGGGAGCGGCCGGGAGGGCGGAGGCCGCCCCGGCCTCGCCTCCGC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
331 | 5_tfbs | Is GABPA occupancy expected at this locus based on the Human DNA sequence provided below? GCAGAGGCTTCTGGCAGTGGTGCGCTAGGAGCAAGTAGAAAAACAACGGCCGTCCGACGGACGTCCGGGAACCTTGGGCGGGGCTCGTGGGGTAGCTTCT | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "GABPA", "true_labels": ["SP1"]} |
332 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CTCCCCCTGCTCACGAGCTCAAGGTCCTTTTCTTGGCTGTGTTTCCGGAGCAGAGGGGCCCGCAGACTCCGCTGGTTCCTGGCAGCCTCCACGGACTGCT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
333 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GGCGGCACATCCGCTTCCCTTCTTCACCTTTCTGGCACCCGCAACACGCAAGCGGCATGAAAGGGCCCTCCGAGGAGAATGTCACCTTTTCTGTCGCAA... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
334 | 5_tfbs | Is the provided Human DNA sequence a target for the ZBTB33 protein? AGGACTCGCTTTCCCAGGGGCCCCCGCGGTCGCAGGGGCAACGAGCCCGGCCGGCCCTCGCGAGCGGAGGCGGGGCCGGGGCCGGAAGTCACGTGCTGTG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "ZBTB33", "true_labels": ["ZBTB33", "SP1"]} |
335 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GTGTACTTCACTGGGCAACACTGTTGGCACACAAGGGACTACAGAACACATTGACATGAGAAAGAGGGCAACTCACAACTGACACACCTCAGAGTGTGGA | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
336 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GCTTGTTCTTGCCTGGACGCCGCACACCAGGTTAGCAGCCACCAGGGGGCACCAAAGCAGCCCATCCCAGAGGAAAGCGTGGGCCTCTGAGCCATTGAAA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
337 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for RELA?
Sequence: CAGCCCTGGGCGGGAGCGGCAACATCTCCACGTCACCCTTTTGGAGCCGCCGACATTCAGAGGGGCAGGACACGGGAACGCGCGCTGTCTTGCTTTACGG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "RELA", "true_labels": ["SP1"]} |
338 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? GAAGGGAGAGGGAATGCAGTGACTGTTCTGTGCCCGGAAGGCTGGGCCAGTCCAGTGCTAGAATCTGGCTGGATGGTTAGTGTGGGATTGAAGCACCTTA | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
339 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? TGGGGGTAAGCGGGAAGCAGCCATGTCCACCAGAGGTCCGCCGGAGCCTCAGCGCGCAGGAGCGGAAGTGGGGTTCGACCAAGGGGTGTGGCGAGCCCGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
340 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the NRF1 binding profile? CCCTAAACTTGAACTCCTGTCTGTGCAGCCTCCAGCCGGCCAGGCGCTAAATAAGGCCACGGCCCGTTTCCTCCTTCAAAAGTCCCTTGTAAAGGGCGAT | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "NRF1", "true_labels": ["SRF"]} |
341 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? ACAGGAGTGTGTCTGGTTCTCAGCTGTGTCCCCAGCACCTTGGACAGTGCCTGGCACATAGTACATGCTCATTGTAGGTTTGATGAGCGAGTGAATGAAT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
342 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? AGGGCCCGGCGCCCAGGGACTCAAAGGACCCTCCCGCGCCCCGCGAGGCTCCGGGGTCTCGGGCTTCCGCCTTCTTGCTGCCCTCGTTCTTGCCAGGGCC | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
343 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the TEAD4 transcription factor? AGACCATACCCAGGAAGCCACATTTCGAGCTATAGGGAAACCACAAGAAAGCTCCAAAAATGGAAGTCCCAGCTTGCTCTCCACAATTATGTCATTTTTC | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "TEAD4", "true_labels": ["SRF"]} |
344 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? AGGTGTCAGCAGTTTCAGTTGCTCCTGAGGCCTCTCTAATCGGCTTGCAGATTGCCATTTTCTCACTGTGTCCTCACATGGCACATGGCCATTCCTCTAT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
345 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? AGAGATAAAGGGCATCCACATCAGTAAAGAGGAAGTCAAACTGTTGCTGTTTGCTGATATGATTGTTTACCTAGAAAACCCTAAAGCCTCCTCCAGAAAG | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
346 | 5_tfbs | Is the provided Human DNA sequence a target for the MAX protein? GTTAGCCTCAGCAAACTCACACAGGAACAGAAAACCAGCGAGACCGCATGGTCTCACTTATAAGTGGGAGCTGAACAATGAGAACACATGGTCACATGGC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "MAX", "true_labels": ["MAX"]} |
347 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GCTCACCCAAAGCCACAGCGAGGAGCAGAGACAGGGACTTCATGGCGCTGCGACCTCCTCAGCCATGAAGCCTCCTCTTCCTCCTTTCACTTTCACTTTC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
348 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TTCTGTTTTAGGCACTCACTGGCTCTCTCTCAGATTAGGAGCTGCATGTGGTGAGGAGTTGACACCTCCTGTCAACAACCACCTGAATAAGCTTGGAAGC | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
349 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the GABPA transcription factor? GCTGGAAAGTTGCCCTTAAGGAAGTGACATTTAGGCTGATACTGAAAGATAAAAAGCTAGGTATGCAAAAGTTGAGAAAGGGAAAGAGGAACTTTAGGCA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "GABPA", "true_labels": ["GABPA", "POU5F1"]} |
350 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? CAAACCGTGGTGCGTCATGCCATGGGATATCCCGCCGCAGCAAAGAGGAACCAGCCACTGACCAGCACGCATGGTGGCTGGAACCCAAACTTGAAAATGA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
351 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCAGACGTGCGTAATTTTAAAGCTCCCTCTGGTGGTTCTACTGA... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
352 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the REST binding profile? CCCGCCGCCCCGCGGCGCAGCCTGAGCGCCACACAAAGGACGCGGCCGACTCTAGCGACCCTGCGGCGCTCCCGGGCGCGAGCCGCCGGGGTCGGGCGGG | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "REST", "true_labels": ["SP1"]} |
353 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TCATTCCTCCCGGCACGCGCGGAGAGGGACTGTGATTGTTCACTTTACACGTCACTCTTTGTGACGTCCCCGGCGGGGGCGGGAAAAAGGAGGCGGACGA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
354 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GGTAAACTTTCCTCCACATTCCATACATTCGTAGGGCTTCTCTCCAGTGTGGATTCTCTGGTGCTGATAGAGGTGTGAGCTCTGGCTGAAGGCTTTCCC... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains TEAD4, No CTCF"} |
355 | 5_tfbs | I need to know if NRF1 is likely to bind to this DNA fragment: TCCCCTCCCCCCTTGCTCACTTATGTGCTGTGCATCCCGCTCCGATCTCCCGCCAACCCCGCCGACCCCTAAACTTTAGAGGGGAAATGGGAGGGCACAT | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "NRF1", "true_labels": ["SP1"]} |
356 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? CCCCTGGGAGCCGCAGCTGTTCTGCCGTATGGGGGAGGGGAACGCTTTCCAACAGTCATCTCTTCCTCTTCAGGCCGCCAACGCCGACCGCACCACAGTC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
357 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CTGCTCGCCCCGCCCGGGCTGCCGAGCCCGAGGCAGGGGTGGCGGGAAGTGGGGGCGGGCGGAGCAGGGCCGGCCTGTGCGGCTCTCGGACCCCGGCTC... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
358 | 5_tfbs | Hypothesis: The transcription factor CTCF binds to the following Human DNA sequence. Is this true? CTGGACTAGGAAGGCCCTGCTCCCGACCGACCCGGAGCGCGCTGCTGCCCTCTACCGGTCATCCGTGCGGCCGGACACCGTGTCAGGCCCGCGAGGAGGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "CTCF", "true_labels": ["ZBTB33", "CTCF"]} |
359 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CATGTTACAGGCTACACGGTGTGTGGTCAGCTTCGCAGTTGTGTTTTAGAAGGGCAAAAAGGGCCCTTTTTTGCTTACGGTATTCTTTCCAATCTGGGCT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
360 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? TTTCTGTCTCCCTTCCGCCCCGCATGTATCCTGACGACCAGAAACGCCCTCTACTTGAGATAACTGGAGCTGGACTCTGCCTCCTGCAATGCAAAGAAC... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
361 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the CTCF binding profile? AATCTGTGGTCCCCACTCCAGTCACTCTGGACTTTCCAAGATGCAAATTTGCACACTGTGAACCTCTGCTATAAACCATTCACTGGCTTCTCCTGGCTCT | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "CTCF", "true_labels": ["RELA", "POU5F1"]} |
362 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GCCGCGCCCGTCCGCGGCGCCGCCAGCCAGGGCGGAAACGGCTGCGGCTTCGCTAGGGACGCATGCGCGGGTCCCTTAGTTTTCGCGAGATAACGGTCGA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
363 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TAAGAGGCCATAGCACCGAAAAGCAGCGTGGGCGCCGGCTGAGGCTTCTCCCAGCCCGTGGGTGGCAGCGTGCTAGCACACTGCCACCATCTCAAAGCCA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
364 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for STAT1?
Sequence: GTTTGGGCACCCAGGCTATGAATGAGGCAGGGTCTTGCAATTGTGGACTAGAAGATTAGCAGCCTAGAAAAGTCACTTATCTTGCTGCCTCAGGTTCTTA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "STAT1", "true_labels": ["GATA2"]} |
365 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CTTAAAGAAATTTACTTTTTTCAGGGAAAGCTTCACCTCCCAACGTTAGTAGGGGAACACACATATCGGCGGATTGCAAGCACCCCCAAGTTATAAAAAT | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
366 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CGGGGCGGGGTGGGGCGGGGAGAACGAGGGCGTTCTCGCGAGATTTGCCTCCTCCCGGTCCCAGCTCCCCGCACCTTCTCGGCCTCTGTCTGGGTCCCC... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
367 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for YY1?
Sequence: TTGCAACTGCTGAACTCTGCCCTTGTAGTGTGAAAACAGCCACAGACCAAATGTAAAAGAATAAACATGGCTGTTTCAACAAAACTTTACTTACAAAAAT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "YY1", "true_labels": ["YY1"]} |
368 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? ATAAATTTTAAAATTCGCGAGAGTTGCTTCCACTCTCGTGAGACCTCCTGCGCGTTAAGCCTCACCCGCGAAGGCTCTCCACGCAGGAAGAAGATCAAGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
369 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CCCTGCGGCAGGAGGAGGCGGAGCCCCCGCTCTCGCCCCGCCCCCACCTCACGTGACCCGCACGGCGCCTCGAGGCCGGAAGCGATTGCGAGCCAGCGCG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
370 | 5_tfbs | I need to know if TEAD4 is likely to bind to this DNA fragment: CCAAGGAGGAAGAAGAGGAACCAGGTGCTGGCACCCCAGGTCGCAAACACATGCACTCCCCCTCAGCCCCGGAGCACGGGGCCTCGTTGCCTTGTCCCTC | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "TEAD4", "true_labels": ["MAX"]} |
371 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? CTGGGCAACAGTCAACTCCAGTCAACCAGGACCTGTGTGTAAGAATGTGAGCTTTGCTGTCAGGGACTCTGGTTGGCTGTGAGTGACCACCCCCGGAATG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
372 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GATTTCCAAAGAAAAATGGCATGTCAGTAACACTTATCTACAGTAACGAAAGCAGCTAGATTTCAGATATACGCATACAAGAGGAAGTGCCGACCTAATC | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
373 | 5_tfbs | I need to know if JUN is likely to bind to this DNA fragment: CAGGGATGCCCCAAGGAACTGCACTGCCTGTTCCTTCCAGAGGGGGGAGCCACAGTGAGGACATGGATTGGTTCTTGATCCAGAACTCTCCCTCCAGAGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "JUN", "true_labels": ["JUN", "CTCF", "GABPA", "RELA"]} |
374 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? CTGTAGCTACTAGGTGATGGGGTGGCTGGTTGGGGTGTCACGTGGTGGTCCATACAGGGTGATGCACTGGCATATGGTGCTAGCATACAATGCAAGAACT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
375 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GGTTTTTGCTTTGAATTGTTCACCTACCTGTGACATTCCTCACTGATAACTCATTGTAAATAGGTCAATATGCTGGCAAATGTTTTCTTTTTTCTTTTC... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains TEAD4, No CTCF"} |
376 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the POU5F1 transcription factor? AGAAGATGGCGGGAATTGCCATATTGAGTGAACCCAGTTTCTAATGGCCTGCATTTGCATATCAAAGCTTGCGGGCTCCGCCCTTCAAGCTGCCTTTTCT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "POU5F1", "true_labels": ["POU5F1", "YY1"]} |
377 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GGCTGGGACCCGGCTGCGCGGCCTTCGTCCAAAATACACAGAACGGCTGGTATCCACAGGAGGCCCCATCGCACGGCAGAACTGGTGACCGGACACAAAA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
378 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GGAATTAGTGTAACATTCCTGCATAAATGCATTGTATACTCTGTAAAACCTGCTGTGAAAAAAAAAGTTGATTAAGAATGCAGGAATCTGGTTAATTTGC | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains TEAD4, No CTCF"} |
379 | 5_tfbs | Hypothesis: The transcription factor NR3C1 binds to the following Human DNA sequence. Is this true? AAACTTTTCTTTTTTTATTGTTGCCATGTCCCTGTGTTGACATTACAGAATGTTCTCTGCCTCCGTGCTCCTGGGGACATTGACAGACCAGCTGAGTTGC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "NR3C1", "true_labels": ["NR3C1"]} |
380 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? CAGAAGCGCGGCCTAGGCTCGGCCAGCAACAGCGACTCCTGGGAGGGTCCTGCGCCCTCGGGGGTGCCCCAGGCGCCGAGGCTGCGCGCGGGGCGTTCCA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
381 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? AACTCAGCGAAGATTTTTTCCTCTGGCCTCGCGCGCCCTGCAGAAGGCGGGGCTGGGGGGTCACCCGAGCCTTCTCCCTGCCGCAGGCTACCTGGGCCCG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
382 | 5_tfbs | Is the provided Human DNA sequence a target for the SRF protein? TGAGGATAATCTCCCTGTCTCTCAAGATCCTTAATCATATCTGCAAAGTACTTTTTTTTTTTTTTTTTTTGCCATATAAGGTAACGTTCACAGGTTCCAG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "SRF", "true_labels": ["SRF"]} |
383 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? CAGTCCGACCCGCGCGCTGCGCCCCTGCTGAGCGGCGCGGAGCTACCACGCCCTGCCAGACTCGCCCTTGGGTCCCTGTCTGACGAGCTCTAGGCAATCT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
384 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TAGGGTCTTTTATTTTCCTGGGAGGCAAGAAGTCCCAGTCCTCCTCCAGAGCCCCAGCTGCCACCTGCTGGTTGTCAATTTTAACCTCATAAGTAGCATT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
385 | 5_tfbs | I need to know if SRF is likely to bind to this DNA fragment: GCCACCATGCCCGGCTAATTCTGTATTTTTAATAGAGGCGGGGTTTCACCATGTTGGCCAGGCTGGTTTCGAACTCTTGACCTCAGGTGATCCACCCACC | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "SRF", "true_labels": ["MEF2A", "YY1"]} |
386 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TGCTAACCTGCTTAGGTCTGGCACTTTTTTGCGTCAAGGGCAGAAATAATTGTTGAAGAAGGTACATCCAGCATTCAACAGTGTGCAAGATGCACACTTT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
387 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CCACGTGGGTGGGGCCAGATGGGGGTGGATGTTGAAACCGGATGCAAAACCCATAGCAGGCAAGAAAAAGGCAAACACCTCATGCAGTTTGGTGTCTGGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
388 | 5_tfbs | Can you confirm the presence of a EGR1 TFBS in this Human DNAsequence? TCTATTTATATTTTATTGTGCTATGTCTTGAAATGTTGTTGTAGCTATTACTTTTGATTGGATATTACTTAGTATTCCTACTTTAAATAAGAGTAGTTTG | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "EGR1", "true_labels": ["MEF2A"]} |
389 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TGTGGGACAAGACTCATCAACACGCACCCAGGACGTCCCTGCCGACCGGAGCCGGTCCGGGGAAGCAAGACGACAGGACCACAGGGGCCGGCCGACGGGC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
390 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? ATAGGGAAAAGGAAAGTGAAGCGTTTCCTGAGTTCGGGGGTCGGCGGAAGATGGCGGCCGGCGAAAGGAGCTGGTGCCTGTGCAAGTTGTTGAGGTGAGC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
391 | 5_tfbs | I need to know if POU5F1 is likely to bind to this DNA fragment: TGCAGATTCCTCCCATCCACATGAAACCACCCCCTTCTCATCAGATAGCACCTTCCCTTGCCTCGTGATGCAAACTGCTTCTCTAACTACTGCAGAGTAC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "POU5F1", "true_labels": ["POU5F1"]} |
392 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TCTTCTAGGAAAAGTTTCTCATTAGCATTTCTATAGGGAGCAGCTGCTACCCTATCTACCCCTATTATCTGATGGCCAGGGCAATGGGGTTGACTGGGAG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
393 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CCAGGGCGCCAGGACCCTGCGCTGTCCGCCGTGGCCGGCGCGTCCACACGGTGGCGCGCCGCACAGCCTGTCCGCTCTGGCCCGCCCGGCTCGCTGGTG... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
394 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the POU5F1 transcription factor? CACCGGCTCTGACCAGGAGTTTGGGGAGCTTCAGGACATTGCTGTGCTTTGGGGATTCCCTCCACATGCTGCACGCGCATCTCGCCCCCAGGGGCACTGC | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "POU5F1", "true_labels": ["RELA", "REST"]} |
395 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? GCAGTTTTATGTTGGCCAGTCAGATGATGTCCTGGATGACAATGGAACTTTCATGGGCCACCTTCTAAGTTCGAGCTGTGTGGTGTGGCAGTCCCTCTTT | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
396 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CACCCCCTCCCAGTGCTGGAGCCACAGCGACACCTACTGGCCACGGACACCTAGGCCACCCCCTCCAGGACGCCCGGGCCCTGTGGTCCATCTGGCCCA... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
397 | 5_tfbs | Is ZBTB33 occupancy expected at this locus based on the Human DNA sequence provided below? GAGACTGACAGCACCGGGACCGACCACGGCCCACCCCTCCGGCCGCGGCGGCCGGGACCAGAACAGCGCAGGCTCTCCGCCCACGCCTGCCCTCGGCTCC | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "ZBTB33", "true_labels": ["SP1", "EGR1"]} |
398 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CCTGCCTCCTGGAGGAACCGTTTTCTGCCCCTCTCCTTGAGTTCTCCGGAGCCCCCCTCGAGGGTCACACCCCCCCGCTTGAGTCCCGCCCTTCTGTGCC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
399 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CTTCCGGGAGGGACGGCACGGGGGCGGCGCCTGCCGGGGGTAGGTGAGCGCCGGAGCCGGACCGGGGACGCGTGATGGGTAGGGCGCGGGGCGGGGTCT... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
400 | 5_tfbs | Is the provided Human DNA sequence a target for the YY1 protein? CGAGCCGTTGCGGGAGAAGGAGGAACCGCAGACCCTGTAATCCCGGCTCGCGGACGGGGTCGGGCACCGGCTTCGCCATTTTCGCTTCAGCTCGCACTGC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "YY1", "true_labels": ["YY1"]} |
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