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800 | Ventricular high-rate episodes in pacemaker diagnostics identify a high-risk subgroup of patients with tachy-brady syndrome. | The purpose of this study was to evaluate the frequency and clinical significance of ventricular high-rate (VHR) episodes (ventricular rate >162 bpm) in patients with symptomatic bradycardia and paroxysmal atrial fibrillation (AF).</AbstractText>Newer pacemakers have enhanced diagnostic features that permit detectio... |
801 | Deaths associated with implantable cardioverter defibrillator failure and deactivation reported in the United States Food and Drug Administration Manufacturer and User Facility Device Experience Database. | The aim of this study was to understand the causes of implantable cardioverter defibrillator (ICD) failure and complications so that adverse events, including unnecessary death, can be prevented.</AbstractText>Sudden death may occur if an ICD fails to treat life-threatening ventricular arrhythmias.</AbstractText>The Un... |
802 | A 25-year control of idiopathic ventricular fibrillation with electrophysiologic-guided antiarrhythmic drug therapy. | The case of a 28-year-old man with recurrent syncope and multiple documented episodes of idiopathic ventricular fibrillation is reported. Recurrent syncope suggesting a self-terminating ventricular tachyarrhythmia occurred after 1 month of amiodarone therapy, and ventricular fibrillation was inducible at electrophysiol... |
803 | Recurrent ventricular fibrillation secondary to aortic valve tumor. | The case of a patient with recurrent ventricular fibrillation secondary to an aortic tumor is reported. Ventricular fibrillation occurs secondary to ischemia, arrhythmia, or congenital disease, or it may be an idiopathic event. Irreversible and recurrent situations require placement of an implantable cardioverter defib... |
804 | Biventricular pacing reduces the induction of monomorphic ventricular tachycardia: a potential mechanism for arrhythmia suppression. | The aim of the present study was to evaluate in a prospective randomized fashion the electrophysiologic effects of acute biventricular (BV) pacing. We hypothesized that (1) the local coupling interval in the left ventricle in response to right-sided ventricular premature beats is prolonged when BV pacing is applied dur... |
805 | Trends in treated ventricular fibrillation out-of-hospital cardiac arrest: a 17-year population-based study. | The aims of this study were to describe the trends of ventricular fibrillation (VF) out-of-hospital cardiac arrest in Rochester, Minnesota, since 1985 and to determine coexistent trends in implantable cardioverter defibrillator (ICD) placement and termination of potentially lethal ventricular arrhythmias that might exp... |
806 | Randomized pilot study of a new atrial-based minimal ventricular pacing mode in dual-chamber implantable cardioverter-defibrillators. | We hypothesized that a new minimal ventricular pacing mode (MVP) that provides AAI/R pacing with ventricular monitoring and back-up DDD/R pacing as needed during AV block (AVB) would significantly reduce cumulative percent ventricular pacing compared to DDD/R.</AbstractText>Conventional DDD/R mode often results in high... |
807 | Diagnostic information in implantable devices that pertain to endpoints in atrial fibrillation studies. | Implantable devices can store significant information about physiologic parameters relating to rhythm and rate control. The primary objective of our analysis was to evaluate the relationship between changes in these parameters and changes in clinical outcomes in patients with atrial tachyarrhythmias (AT). Because the p... |
808 | Ventricular rate control as an endpoint for treatment of atrial fibrillation. | Interest in the use of rate control as an endpoint for managing atrial fibrillation likely will increase given the results of recent randomized clinical trials. As an endpoint, rate control has favorable attributes of ease of measurement and clear numerical definitions. Pharmacologic rate control is achieved in approxi... |
809 | Are there alternatives to mortality as an endpoint in clinical trials of atrial fibrillation? | Although atrial fibrillation (AF) is associated with an increased risk of death in many cohort studies and, therefore, is an endpoint of interest in trials of management of AF, the frequency of occurrence is low. Arrhythmia suppression as a surrogate endpoint for mortality in trials of rhythm management has a bad reput... |
810 | The coronary sinus: passive bystander or source of arrhythmia? | The coronary sinus provides access to the epicardial space of the heart allowing ablation of epicardial accessory pathways, foci of ventricular arrhythmia, and arrhythmogenic areas such as the vein or ligament of Marshall. In addition, its musculature may form atrioventricular accessory connections, participate in macr... |
811 | Epicardial organization of human ventricular fibrillation. | The objective of this study was to test the hypothesis that on the epicardium of the in vivo human heart, ventricular fibrillation (VF) consists of chaotic small wavefronts that constantly change paths.</AbstractText>Despite the significance of VF to cardiovascular mortality, little is known about the wavefronts that c... |
812 | Temporary overdriving pacing as an adjunct to antiarrhythmic drug therapy for electrical storm in acute myocardial infarction. | A-55-year-old man with diabetes mellitus was admitted to hospital because of chest pain. He was diagnosed as anterior acute myocardial infarction and treated with stent placement. After 7 days, ventricular fibrillation occurred because of a subacute reocclusion and balloon angioplasty was performed. Despite reperfusion... |
813 | Combined effects of nifekalant and lidocaine on the spiral-type re-entry in a perfused 2-dimensional layer of rabbit ventricular myocardium. | Spiral re-entry plays the principal role in the genesis of ventricular tachycardia and ventricular fibrillation (VT/VF). The specific I(Kr) blocker, nifekakant (NIF) has, often in combination with lidocaine (LID), recently been used in Japan to prevent recurrent VT/VF, but the combined effects of these drugs on spiral ... |
814 | Idiopathic right ventricular outflow tract tachycardia induced during acute episode of atrial fibrillation.<Pagination><StartPage>150</StartPage><EndPage>153</EndPage><MedlinePgn>150-3</MedlinePgn></Pagination><Abstract><AbstractText>Tachycardia-induced tachycardia is a rare condition. We report a case in which an epis... | Tachycardia-induced tachycardia is a rare condition. We report a case in which an episode of paroxysmal atrial fibrillation led to right ventricular outflow tract tachycardia. We also analyse all potential mechanisms that might contribute to the coexistence of these two different arrhythmias in the same patient.</Abstr... |
815 | Pre-operative atrial fibrillation as the key determinant of outcome of mitral valve repair for degenerative mitral regurgitation. | To examine the impact of pre-operative atrial fibrillation (AF) on the outcome of mitral valve repair (MVR) for degenerative mitral regurgitation (MR).</AbstractText>Among 392 patients with moderate to severe MR who underwent MVR between 1991 and 2002, 283 patients with isolated degenerative MR were followed for 4.7+/-... |
816 | Effect of cardiac resynchronization therapy on inducibility of ventricular tachyarrhythmias in cardiac arrest survivors with either ischemic or idiopathic dilated cardiomyopathy. | We evaluated whether long-term cardiac resynchronization therapy affects the inducibility of ventricular tachyarrhythmias in relation to reverse remodeling in cardiac arrest survivors with either ischemic or idiopathic dilated cardiomyopathy. Clinical, electrophysiologic, and echocardiographic data of 18 patients were ... |
817 | ECG repolarization waves: their genesis and clinical implications. | The electrocardiographic (ECG) manifestation of ventricular repolarization includes J (Osborn), T, and U waves. On the basis of biophysical principles of ECG recording, any wave on the body surface ECG represents a coincident voltage gradient generated by cellular electrical activity within the heart. The J wave is a d... |
818 | Factors associated with poor survival in women experiencing cardiac arrest in a rural setting. | The purpose of this study was to determine whether gender differences exist in the characteristics and outcomes for out-of-hospital cardiac arrest (OHCA) occurring in a rural setting.</AbstractText>In urban settings, women have a lower incidence of OHCA than men but otherwise a comparable survival for ventricular fibri... |
819 | Long-term results after ablation of infarct-related ventricular tachycardia. | The purpose of this study was to assess the long-term effects of ablation of infarct-related ventricular tachycardia (VT) and the subsequent requirement for implantable cardioverter-defibrillator (ICD) therapy.</AbstractText>The long-term consequences after initially successful catheter ablation of infarct-related VT r... |
820 | Defibrillation threshold testing: is it really necessary at the time of implantable cardioverter-defibrillator insertion? | The purpose of this study was to (1) determine how often implantable cardioverter-defibrillator (ICD) system modifications were needed to obtain an adequate safety margin for defibrillation, (2) identify how often and for what indications defibrillation threshold (DFT) testing was not performed, and (3) identify factor... |
821 | [Plasma Nt-proBNP concentration during heart failure therapy]. | To study the changes of plasma Nt-proBNP levels obtained at multi-time-points during heart failure patients underwent treatment and the relationship between the concentrations to the patients' clinical improvements.</AbstractText>Forty heart failure patients and 41 normal control patients were chosen. The heart functio... |
822 | Effect of incessant ventricular tachyarrhythmias on serum endothelin and big-endothelin levels. | Endothelin-1 (ET-1) is a potent endogenous arrhythmogenic substance. The aim of our study was to investigate the changes of serum ET-1 and big-endothelin levels in patients suffering from spontaneous, incessant ventricular tachyarrhythmias. The 11 consecutive patients' (mean age, 59 +/- 11 years) underlying diseases we... |
823 | Effects of experimental diabetes on endothelin-induced ventricular arrhythmias in dogs. | Endothelin-1 (ET-1) is known to have a direct arrhythmogenic effect in the mammalian heart. Diabetes mellitus is accompanied by a series of endothelial and cardiac disfunctions; however, little is known about ET-1-induced direct arrhythmias in diabetes mellitus. Therefore, we infused ET-1 (33 pmol/min) into the left an... |
824 | Changes of endothelin-1 and big endothelin-1 levels and action potential duration during myocardial ischemia-reperfusion in dogs with and without ventricular fibrillation. | Myocardial ischemia-reperfusion is associated with increased production of endothelin-1 (ET-1). Moreover, exogenous ET-1 has arrhythmogenic properties. Our aim was to investigate the correlation between endogenous ET-1, big ET-1 levels and epicardial monophasic action potential duration during myocardial ischemia-reper... |
825 | Myofiberbreak-up: a marker of ventricular fibrillation in sudden cardiac death. | Electrophysiologically, ventricular fibrillation is defined as a "chaotic, random, asynchronous electrical activity of the ventricles due to repetitive re-entrant excitation and/or rapid focal discharge". To this point its morphological equivalent has not been defined.</AbstractText>Several groups of different diseases... |
826 | Automatic impedance monitoring and patient alert feature in implantable cardioverter defibrillators: being alert for the unexpected! | Recent advances in implantable cardioverter defibrillator (ICD) technology have enabled implementation of an automatic monitoring feature in ICDs that provides daily measurements of several technical parameters such as battery status, pacing, and high-voltage impedance. The system alerts the patient with an audible ala... |
827 | Role of streptomycin-sensitive stretch-activated channel in chest wall impact induced sudden death (commotio cordis). | Deaths secondary to low-energy impacts to the precordium in young individuals (commotio cordis) have been reported with increasing frequency. In a swine model, baseball impacts induce ventricular fibrillation when directed at the center of the left ventricle during the vulnerable portion of repolarization just prior to... |
828 | Regional variation in capture of fibrillating swine left ventricle during electrical stimulation. | While it has been shown that electrical stimulation can capture a region of myocardium during ventricular fibrillation (VF), the ideal location to stimulate to maximize capture of the fibrillating in vivo left ventricle (LV) is not known. We previously demonstrated a mean directionality to the propagation of VF wavefro... |
829 | Short QT syndrome and atrial fibrillation caused by mutation in KCNH2. | The short QT syndrome is a newly described clinical entity characterized by the presence of a short QT interval associated with cardiac tachyarrhythmias including sudden cardiac death at a young age in otherwise healthy individuals. A genetic basis has been identified linking the disease to mutations in KCNH2 in the fa... |
830 | Clinical and electrophysiological characteristics of Brugada syndrome caused by a missense mutation in the S5-pore site of SCN5A. | Brugada syndrome is an inherited cardiac disorder caused by mutations in the SCN5A gene encoding the cardiac sodium channel alpha-subunit, and potentially leads to ventricular fibrillation and sudden death. We report a case of a novel SCN5A mutation associated with Brugada syndrome. A 51-year-old man suffered from recu... |
831 | [Nifekalant hydrochloride as an effective treatment for postoperative ischemic heart disease]. | We experienced 2 effective cases of nifekalant hydrochloride. One patient was 76-year-old female who underwent emergent coronary artery bypass grafting (CABG) because of unstable angina pectoris (AP) and ventricular fibrillation (Vf). Her cardiac function had been decreased preoperatively due to old myocardial infarcti... |
832 | [Infarct exclusion for postinfarction left ventricular free wall rupture with severe congestive heart failure]. | A 70-year-old man was transferred to our hospital with severe congestive heart failure and ventricular arrhythmia due to acute myocardial infarction. He had experienced chest pain 3 weeks previously and was admitted to another hospital for dyspnea, where he required assist ventilation, 1 week prior to the transfer. An ... |
833 | Safe performance of magnetic resonance imaging on a patient with an ICD. | This is a report on a patient with an implanted cardioverter defibrillator (ICD) who intentionally underwent magnetic resonance imaging (MRI) of a malignant brain tumor. To avoid inadequate detection of ventricular tachycardia (VT) or ventricular fibrillation (VF), the ICD was inactivated by programming the VT-detectio... |
834 | Transcoronary ablation of septal hypertrophy does not alter ICD intervention rates in high risk patients with hypertrophic obstructive cardiomyopathy. | Transcoronary ablation of septal hypertrophy (TASH) is safe and effectively reduces the intraventricular gradient in patients with hypertrophic obstructive cardiomyopathy (HOCM). To analyze the potential of anti- and proarrhythmic effects of TASH, we studied the discharge rates of implanted cardioverter defibrillators ... |
835 | Atrial pacing should be used more frequently in sinus node disease. | Single lead atrial (AAI(R)) pacing for sick sinus syndrome provides physiological pacing and is less expensive than a dual chamber system. Compared with ventricular-based pacing, it maintains the normal cardiac depolarization sequence, is associated with less atrial fibrillation and heart failure, and avoids pacemaker ... |
836 | Clinical, echocardiographic, and electrocardiographic abnormalities in Boxers with cardiomyopathy and left ventricular systolic dysfunction: 48 cases (1985-2003). | To identify clinical, echocardiographic, and electrocardiographic abnormalities in Boxers with cardiomyopathy and echocardiographic evidence of left ventricular systolic dysfunction.</AbstractText>Retrospective study.</AbstractText>48 mature Boxers.</AbstractText>Medical records were reviewed for information on age; se... |
837 | Electrophysiological concept of ventricular defibrillation mechanism. | Sudden cardiac death is a major health problem in most industrialized countries around the world including Thailand. It is mainly caused by ventricular fibrillation (VF). Currently, defibrillation is the only effective clinical treatment of this fatal arrhythmia. Although defibrillation mechanism has been investigated ... |
838 | [Cardiac resynchronization therapy and arrhythmias]. | Cardiac resynchronization therapy (CRT) is now considered an established therapy for patients with chronic heart failure in the presence of a wide QRS complex. Though proarrhythmic effects have been described in a few cases, CRT did not increase the frequency of ventricular tachyarrhythmias in prospective studies. In p... |
839 | Respiratory medications and the risk of cardiac arrhythmias. | Medications used to treat respiratory diseases include beta-adrenoceptors, antimuscarinics, inhaled and oral corticosteroids, and theophyllines. Most of these drugs have been associated indirectly with cardiac rhythm disorders, but epidemiologic evidence is limited.</AbstractText>To evaluate the association between res... |
840 | Clinical and echocardiographic determinants of long-term survival after surgical myectomy in obstructive hypertrophic cardiomyopathy. | Surgical myectomy has been the standard treatment for patients with drug-refractory obstructive hypertrophic cardiomyopathy. The clinical and echocardiographic predictors of long-term survival and freedom from cardiovascular morbidity after myectomy have been unclear.</AbstractText>We studied a consecutive cohort of 33... |
841 | P wave signal averaged ECG and chemoreflexsensitivity in paroxysmal atrial fibrillation. | Detailed analysis of the QRS-complex and autonomic dysfunction can identify patients at risk to suffer from ventricular arrhythmias. To determine whether patients at risk for paroxysmal atrial fibrillation (PAF) could be identified while in sinus rhythm, a P wave triggered signal averaged ECG and an analysis of the aut... |
842 | [Nibentan -- a drug for pharmacological cardioversion of persistent atrial fibrillation]. | To assess efficacy of a potassium channel blocker nibentan for pharmacological cardioversion of persistent atrial fibrillation. Method. Nibentan (1% solution) was infused intravenously after 3 weeks of warfarin pretreatment to 31 patients with duration of atrial fibrillation from 4 weeks to 15 months.</AbstractText>Sin... |
843 | Cariporide potentiates the effects of epinephrine and vasopressin by nonvascular mechanisms during closed-chest resuscitation. | The efficacy of vasopressor therapy during closed-chest resuscitation is limited and decreases over time. We previously reported that sodium-hydrogen exchanger isoform-1 inhibition during ventricular fibrillation (VF) using cariporide ameliorates ischemic contracture and enhances the efficacy of chest compression. We c... |
844 | Impact of congestive heart failure and left ventricular systolic function on the prognostic significance of atrial fibrillation and atrial flutter following acute myocardial infarction. | Reports on the prognostic importance of atrial fibrillation following myocardial infarction have provided considerable variation in results. Thus, this study examined the impact of left ventricular systolic function and congestive heart failure on the prognostic importance of atrial fibrillation in acute myocardial inf... |
845 | Left ventricular aneurysm repair: early survival. | The aim of this study was to evaluate the early survival in patients submitted to left ventricular (LV) repair and concomitant myocardial revascularization.</AbstractText>We retrospectively reviewed the records of 51 patients who were submitted to LV repair and concomitant myocardial revascularization between January 1... |
846 | Clinical evaluation of an inspiratory impedance threshold device during standard cardiopulmonary resuscitation in patients with out-of-hospital cardiac arrest. | To determine whether an impedance threshold device, designed to enhance circulation, would increase acute resuscitation rates for patients in cardiac arrest receiving conventional manual cardiopulmonary resuscitation.</AbstractText>Prospective, randomized, double-blind, intention-to-treat.</AbstractText>Out-of-hospital... |
847 | Reprogramming of the human atrial transcriptome in permanent atrial fibrillation: expression of a ventricular-like genomic signature. | Atrial fibrillation is associated with increased expression of ventricular myosin isoforms in atrial myocardium, regarded as part of a dedifferentiation process. Whether reexpression of ventricular isoforms in atrial fibrillation is restricted to transcripts encoding for contractile proteins is unknown. Therefore, this... |
848 | Propranolol intoxication revealing a Brugada syndrome. | This is the first report of Brugada syndrome revealed by beta-blocker intoxication. A 24-year-old healthy man ingested propranolol (2.28 g) to commit suicide. After early gastric lavage, electrolytes, cardiac enzymes, chest X-ray, and echocardiography were normal. Dosages of psychotropic drugs were negative. ECG showed... |
849 | An autopsy case of Brugada syndrome with significant lesions in the sinus node. | A 30-year-old man with Brugada syndrome died suddenly. The heart weighed 380 g. The left ventricular wall showed mild thickening, and marked fatty tissue deposition was noted in the right ventricular outflow tract. Neither ventricle was enlarged. Contraction band necrosis was diffuse in both ventricles. In the ventricl... |
850 | Unsuccessful internal defibrillation in Brugada syndrome: focus on refractoriness and ventricular fibrillation cycle length. | In patients with Brugada syndrome, implantable cardioverter defibrillator (ICD) is the only reliable treatment to prevent sudden death though, in some cases, internal defibrillation may be unsuccessful. The aim of this study was to examine the determinants of defibrillation failure, with a focus on electrophysiologic c... |
851 | [Semiautomatic external defibrillation: use inside a hospital]. | The electric rhythm which provokes the majority of the cases of sudden death is ventricular fibrillation, and the only effective measure to reestablish spontaneous circulation consists in administering a precocious electrical discharge, or defibrillation. Time is a fundamental factor since the possibilities tor surviva... |
852 | Plasma concentration of atrial natriuretic peptide is related to the duration of atrial fibrillation in patients with advanced heart failure. | Plasma concentration of atrial natriuretic peptide (ANP) is elevated in patients with atrial fibrillation (AF) and in patients with chronic heart failure (CHF).Aim. To assess ANP level in patients with permanent AF and advanced CHF.</AbstractText>The study group consisted of 41 patients (27 males, mean age 62+/-8 years... |
853 | Role of postoperative use of adrenergic drugs in occurrence of atrial fibrillation after cardiac surgery. | Use of adrenergic (inotropic and vasopressor) drugs is common after cardiac surgery.</AbstractText>The study was undertaken to evaluate the role of postoperative adrenergic drug use as a predictor of postoperative atrial fibrillation (AF) after cardiac surgery.</AbstractText>The study population consisted of 199 patien... |
854 | [What do we actually know about out-of-hospital cardiac arrest?]. | Each year at least 300,000 people in the United States and 8000 to 10,000 people in Switzerland suffer from out-of-hospital cardiac arrest, mostly due to ventricular fibrillation. Early defibrillation provides definitive treatment for most of cardiac arrest victims. Semi-automatic external defibrillators are easy to ha... |
855 | A comparison of cardiac resynchronization by sequential biventricular pacing and left ventricular pacing to simultaneous biventricular pacing: rationale and design of the DECREASE-HF clinical trial. | The first generation of cardiac resynchronization therapy (CRT) devices approved for the treatment of heart failure used simultaneous biventricular (BiV) pacing to achieve ventricular resynchronization. Left ventricular pacing alone and sequential BiV pacing also show promise as alternative ways to deliver CRT, but hav... |
856 | Prolonged repolarization after ventricular assist device support is associated with arrhythmias in humans with congestive heart failure. | Recent observations indicate that the QTc interval often increases in the early postoperative period (<1 week) after mechanical unloading of severely failing hearts with a left ventricular assist device (LVAD). The present study examined whether early changes in ventricular repolarization after LVAD placement are as... |
857 | Congestive heart failure and atrial fibrillation: rhythm versus rate control. | The incidence both of heart failure and atrial fibrillation is steadily increasing in the United States' population, and these conditions frequently coexist in the same patient. It is likely that the onset of one of these disorders leads to the onset and propagation of the other through multiple mechanisms. Several stu... |
858 | An arrhythmia classification system based on the RR-interval signal. | This paper proposes a knowledge-based method for arrhythmic beat classification and arrhythmic episode detection and classification using only the RR-interval signal extracted from ECG recordings.</AbstractText>A three RR-interval sliding window is used in arrhythmic beat classification algorithm. Classification is per... |
859 | Infarct morphology identifies patients with substrate for sustained ventricular tachycardia. | We sought to evaluate whether infarct size characterization by cardiac magnetic resonance imaging (MRI) is a better predictor of inducible ventricular tachycardia (VT) than left ventricular ejection fraction (LVEF).</AbstractText>Inducibility of VT at electrophysiologic study (EPS) and low LVEF can identify patients wi... |
860 | Depression as a predictor for appropriate shocks among patients with implantable cardioverter-defibrillators: results from the Triggers of Ventricular Arrhythmias (TOVA) study. | We sought to examine the relationship between symptoms of depression and shock-treated ventricular arrhythmias among implantable cardioverter-defibrillator (ICD) patients.</AbstractText>Depression predicts mortality in patients with coronary artery disease (CAD), but whether this is via an increased risk of fatal ventr... |
861 | The prognostic importance of left ventricular outflow obstruction in hypertrophic cardiomyopathy varies in relation to the severity of symptoms. | The aim of this study was to investigate whether the prognostic importance of left ventricular (LV) outflow obstruction in hypertrophic cardiomyopathy (HCM) is influenced by other predictors of morbidity and mortality.</AbstractText>It remains unknown whether the effect of outflow obstruction on clinical outcome in HCM... |
862 | N-Terminal-proBNP (NT-proBNP) as an indicator of cardiac dysfunction. A study in patients presenting with suspected cardiac disorders. | Natriuretic peptides represent a novel diagnostic tool in the assessment of cardiac dysfunction.</AbstractText>A total of 473 consecutive referred patients presenting to 18 cardiologists for the assessment of their cardiac state were recruited for the study. Patients received a medical history, a physical examination a... |
863 | The effect of tirofiban and clopidogrel pretreatment on outcome of old saphenous vein graft stenting in patients with acute coronary syndromes. | In spite of developments in interventional cardiology, the success rate of saphenous vein graft stenting is still low in patients with acute coronary syndromes. In this study, we aimed at finding out the effect of pretreatment with Tirofiban, a glycoprotein IIb/IIIa inhibitor, and clopidogrel, an adenosine diphosphate ... |
864 | Effects of oxypeucedanin on hKv1.5 and action potential duration. | A furocoumarin derivative, oxypeucedanin, was purified from Angelica dahurica, and its effects on the human Kv1.5 (hKv1.5) channel and on the cardiac action potential duration (APD), were examined using the patch-clamp technique and the conventional microelectrode technique. Oxypeucedanin inhibited the hKv1.5 current i... |
865 | [Importance of critical events training for anesthesiology residents: experience with computer simulator.]. | Because of monitoring and drugs evolution, there has been a decrease in the incidence of critical events during anesthetic procedures. Despite this low frequency, critical event training for Anesthesiology residents remains important. This study aimed at evaluating Anesthesiology residents' critical care skills during ... |
866 | Estimation of cardiac event risk by MDCT. | Coronary calcifications are specific markers for coronary atherosclerosis. The amount of coronary calcium is related to the likelihood of vulnerable plaques. Vulnerable plaques may rupture and may result in sudden coronary thrombus formation, occlusion, ischemia and ventricular fibrillation and finally cardiac death. T... |
867 | Surgical ventricular restoration in end-stage ischemic cardiomyopathy patients. | Surgical ventricular restoration (SVR) has generally been contraindicated in patients with an ejection fraction (EF) <20%, with pulmonary arterial (PA) pressure >60 mm Hg, and being treated with inotropic agents.</AbstractText>The patients in this study were 6 men and 5 women 50 to 78 years of age (mean, 62.4 yea... |
868 | Ethnicity and variation in prognosis for patients newly hospitalised for heart failure: a matched historical cohort study. | To compare mortality and factors predictive for outcome in age matched white and South Asian cohorts after first admission for heart failure.</AbstractText>Matched historical cohort study.</AbstractText>One National Health Service trust comprising three acute care hospitals.</AbstractText>176 South Asian (mean age 68 (... |
869 | Effect of hypothermia on transthoracic defibrillation in a swine model. | Induced hypothermia (H) appears a promising intervention to protect the heart and brain after resuscitation from cardiac arrest. However, the influence of H on transthoracic defibrillation energy requirements is not well documented.</AbstractText>In 39 swine (21.4+/-1.3(S.E.) kg) hypothermia was induced by surrounding ... |
870 | Differences in time to defibrillation and intubation between two different ventilation/compression ratios in simulated cardiac arrest. | During basic life support (BLS) by a two-rescuer-team early defibrillation and ALS procedures should be performed without interruptions of the BLS-ventilation/compression sequence. The objective of this study was to determine the impact of a ventilation/compression ratio of 5:50 versus 2:15 on the time intervals "Start... |
871 | Risk factors for first-ever ischemic stroke: a hospital-based case-control study in Kaohsiung, Taiwan. | Numerous population-based epidemiological studies have shown the prevalence and strength of vascular risk factors for stroke but little is known about risk factors of stroke in Taiwan. The aim of this study was to identify vascular risk factors in a group of first-ever ischemic stroke patients in Taiwan.</AbstractText>... |
872 | The new selective I(Ks)-blocking agent HMR 1556 restores sinus rhythm and prevents heart failure in pigs with persistent atrial fibrillation. | Antiarrhythmic drugs for treatment of atrial fibrillation in patients with heart failure are limited by proarrhythmia and low efficacy. Experimental studies indicate that the pure I(Ks) blocking agents chromanol 293b and HMR 1556 prolong repolarization more markedly at fast than at slow heart rates and during beta-adre... |
873 | A randomized controlled trial of magnesium sulfate, in addition to usual care, for rate control in atrial fibrillation. | We examine the safety and efficacy of magnesium sulfate infusion, in addition to usual care, for acute rate reduction in patients with atrial fibrillation and a rapid ventricular response rate.</AbstractText>This was a prospective, randomized, double-blind, placebo-controlled trial of intravenous magnesium sulfate in a... |
874 | Clinical, echocardiographic, and hemodynamic characteristics of rheumatic mitral valve stenosis and atrial fibrillation. | Chronic atrial fibrillation (AF) is associated with an increased frequency of embolic events and negative impact on cardiac function, and therefore, an increased morbidity and mortality risk in patients with rheumatic mitral valve stenosis (RMS). In the present study, the clinical, 2-D and Doppler echocardiographic, an... |
875 | Diltiazem versus amiodarone to prevent atrial fibrillation in coronary surgery. | The prophylactic effect of amiodarone on atrial fibrillation after coronary bypass grafting with extracorporeal circulation was compared with that of diltiazem in two groups of 60 patients each. Patients were monitored continuously for 8 days. The incidence of atrial fibrillation was recorded retrospectively in a contr... |
876 | Minimal access via lower partial sternotomy for congenital heart defects. | To evaluate the invasiveness of a minimal access approach for simple congenital heart defects, and determine whether it can be regarded as a standard operation, 83 patients with an atrial septal defect and 73 with a ventricular septal defect underwent repair through a minimal skin incision and lower partial median ster... |
877 | The Gurvich waveform has lower defibrillation threshold than the rectilinear waveform and the truncated exponential waveform in the rabbit heart. | Implantable cardioverter defibrillator studies have established the superiority of biphasic waveforms over monophasic waveforms. However, external defibrillator studies of biphasic waveforms are not as widespread. Our objective was to compare the defibrillation efficacy of clinically used biphasic waveforms, i.e., trun... |
878 | Permanent His-bundle pacing after atrioventricular node ablation in a patient with chronic atrial fibrillation and mitral regurgitation. | Hemodynamic deterioration because of worsening of mitral regurgitation can occur in a small number of patients undergoing atrioventricular node (AVN) ablation and pacing therapy. Patients with moderate mitral regurgitation before ablation seem prone to this complication. Successful permanent His-bundle pacing after AVN... |
879 | The genetics of cardiac arrhythmias. | Cardiac rhythm problems result in high levels of morbidity and mortality, with sudden arrhythmic death claiming approximately 300,000 lives in the United States each year. Investigations into the genetic contributions to rhythm and conduction disorders have found genes or loci associated with primary rhythm/conduction ... |
880 | The Brugada Syndrome. | In 1992 a syndrome was described consisting of syncopal episodes and/or (resuscitated) sudden death in patients with a structurally normal heart and a characte ristic electrocardiogram (ECG) displaying a pattern resembling a right bundle branch block with ST segment elevation in leads V1 to V3. The disease is genetical... |
881 | [Cardiac arrest outside hospital: initial and subsequent cardiological management]. | The prognosis of cardiac arrest outside hospital is directly related to the initial management. The aim of this work was to evaluate the characteristics of the initial and subsequent cardiological management of victims of cardiac arrest outside hospital with a retrospective analysis of data from the SAMU 35 (Emergency ... |
882 | Current status of mitral valve repair. | Mitral valve repair is the procedure of choice to treat mitral valve dysfunction. Advantages of mitral valve repair over mitral valve replacement include improved long-term survival, better preservation of left ventricular function, and greater freedom from endocarditis, thromboembolism, and anticoagulant-related hemor... |
883 | Pharmacologic therapies for atrial fibrillation. | Pharmacologic therapy for atrial fibrillation may be used for acute cardioversion or ventricular rate control or for long-term therapy to maintain sinus rhythm or control ventricular rates in atrial fibrillation. Therapies must be tailored to elderly patients, with particular attention to structural heart disease, brad... |
884 | [Early post-operative arrhythmias in endomyocardial fibrosis or chronic parietal endocarditis in 84 cases studied at the Cardiology Institute of Abidjan]. | The authors have studied rhythmic events happened during early post-operative period in 84 operated patients for endomyocardial fibrosis, synonym nowadays to chronic parietal endocarditis, in the Institute of Cardiology of Abidjan (Côte d'lvoire), from January 1977 to July 1991. The mean age has been 15.6 +/- 43 y... |
885 | [Effect of omega-3 fatty acids on the prevention of atrial arrhythmias]. | The effects of omega-3 fatty acids on membrane stabilization are well known. Reduction of ventricular arrhythmias and sudden death has been reported; fewer data exist regarding the effects on atrial arrhythmias. The object of this report is to evaluate the reduction of atrial arrhythmia-fibrillation after treatment wit... |
886 | Update in atrial fibrillation. | Atrial fibrillation (AF) is the most common sustained arrhythmia in adults. It is a significant public health problem in the United States where it affects 2.2 million Americans and almost 10% of the population older than 80 years. It should be emphasized that the prevalence of AF increases with advancing age and with ... |
887 | Fatal course of parvovirus B19-associated myocarditis in a female liver transplant recipient. | Acute myocarditis may result in severe hemodynamic compromise with fatal outcome. Furthermore, recent studies suggest myocarditis as a major cause of sudden unexpected death. A variety of cardiotropic viral, rickettsial, and bacterial infectious agents have been identified to date. Parvovirus B19 (PVB19) is usually ben... |
888 | Charging up the public for automated external defibrillators. | Public training in the use of automated external defibrillators to treat out-of-hospital cardiac arrests has been receiving increased attention. The implementation of public access defibrillation programs has been the most significant intervention to improve survival in decades. Dramatic success came when we placed aut... |
889 | Ibutilide for rapid conversion of atrial fibrillation or flutter in a mixed critically ill patient population. | Ibutilide is an intravenous class III antiarrhythmic agent that has been shown to be effective in converting acute onset atrial fibrillation/flutter in stable medical and cardio-surgical patients. Data on its use in critically ill patients are rare. The aim of this open, non-randomized, prospective trial was to assess ... |
890 | The incidence and timing of major arrhythmias following successful primary angioplasty for acute myocardial infarction. | The potential benefits of direct percutaneous transluminal coronary angioplasty (PTCA) on malignant arrhythmias in the hospital phase of acute myocardial infarction have not yet been established.</AbstractText>We prospectively investigated the incidence and timing of major arrhythmias occurring during direct PTCA and w... |
891 | [Cardiology]. | The therapeutic acquisition to be retained for 2004 are: 1. The elderly patients with heart failure also should receive beta blocker treatment. The correction of anaemia, aggravating factor in heart failure, improves symptoms and survival of the patient. 2. It remains to prove that the treatment of sleep apnea, which s... |
892 | C-reactive protein elevation predicts the occurrence of atrial structural remodeling in patients with paroxysmal atrial fibrillation. | It has been poorly understood whether inflammation may contribute to atrial structural remodeling and increase the propensity for atrial fibrillation (AF) to persist. We investigated the relationship between C-reactive protein (CRP) elevation and the development of atrial remodeling in AF. The study population comprise... |
893 | Long term complications in single and dual chamber pacing are influenced by surgical experience and patient morbidity. | To determine how short and long term complication rates after pacemaker implantation are influenced by patient morbidity, operator experience, and choice of pacing system.</AbstractText>Retrospective analysis of 1884 patients who received VVI (n = 610), VDD (n = 371), or DDD devices (n = 903) between 1990 and 2001. Fol... |
894 | Heart failure in patients with preserved and deteriorated left ventricular ejection fraction. | To determine clinical and prognostic differences between preserved and deteriorated systolic function (defined as left ventricular (LV) ejection fractions > or = 50% and < 50%, respectively) in patients with heart failure satisfying modified Framingham criteria.</AbstractText>Records were studied of 1252 patients... |
895 | [Attempt to assess the risk of recurrence of life-threatening ventricular arrhythmia using simple non-invasive tests]. | Baroreflex sensitivity (BRS), as assessed using phenylephrine method, and depressed 24-hour heart rate variability (HRV) have been shown to be powerful predictors of life-threatening ventricular arrhythmias. However, before these tests are widely used, their methodology has to be simplified. The aim of this study was t... |
896 | "W-shaped" volume curve with gated myocardial perfusion single photon emission computed tomography. | Gating errors (GEs) with ECG gated myocardial SPECT (G-SPECT) may occur irrespective of the presence or absence of arrhythmias. We evaluated the impact of GEs on both reconstructed tomograms and left ventricular ejection fraction (LVEF) derived from G-SPECT, and searched for clues to identify these errors.</AbstractTex... |
897 | N-2-mercaptopropionylglycine, a scavanger of reactive oxygen species, does not modify the early antiarrhythmic effect of ischaemic preconditioning in anaesthetised dogs. | The possible involvement of reactive oxygen species (ROS) in the protective effects of ischaemic preconditioning (PC) against arrhythmias was examined in anaesthetised dogs using the ROS scavenger N-2-mercaptopropionylglycine (MPG).</AbstractText>PC was induced in 20 chloralose-urethane anaesthetised dogs by two 5 min ... |
898 | Pyrroloquinoline quinone (PQQ) decreases myocardial infarct size and improves cardiac function in rat models of ischemia and ischemia/reperfusion. | As pyrroloquinoline quinone (PQQ) is a redox cofactor in mammals, we asked if it is cardioprotective. Rats were subjected to 2 h of left anterior descending (LAD) coronary artery ligation without reperfusion (model 1, ischemia). In model 2 (ischemia/reperfusion), rats were subjected to 17 or 30 min of LAD occlusion and... |
899 | Termination of spiral waves during cardiac fibrillation via shock-induced phase resetting. | Multiple unstable spiral waves rotating around phase singularities (PSs) in the heart, i.e., ventricular fibrillation (VF), is the leading cause of death in the industrialized world. Spiral waves are ubiquitous in nature and have been extensively studied by physiologists, mathematicians, chemists, and biologists, with ... |
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