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12,700
Prediction of midterm performance of active-fixation leads using current of injury.
There are only limited prospective data on the clinical relevance of current of injury (COI) as a predictor of the midterm performance of active-fixation leads. This study sought to investigate whether it is possible to predict the midterm performance of active-fixation leads using COI recorded at the time of implantat...
12,701
Ventricular cycle length characteristics estimative of prolonged RR interval during atrial fibrillation.
When atrial fibrillation (AF) is incessant, imaging during a prolonged ventricular RR interval may improve image quality. It was hypothesized that long RR intervals could be predicted from preceding RR values.</AbstractText>From the PhysioNet database, electrocardiogram RR intervals were obtained from 74 persistent AF ...
12,702
Cardiac transplant in a family pedigree of hypertrophic cardiomyopathy secondary to a mutation in the AMP gene.
The phenotype of this unique condition comprises left ventricular hypertrophy (LVH), accessory pathways, atrial arrhythmia and premature failure of the atrioventricular node. At age 11, his ECG showed marked voltage criteria for LVH but his echocardiography was negative. He declined further screening but was reassessed...
12,703
Conductor externalization of the RIATA implantable cardioverter defibrillator lead: a challenging lead extraction requiring laser-powered sheath.
We report the case of a 27-year-old man who received a single chamber implantable cardioverter defibrillator with a St Jude Medical Riata double coil passive lead for secondary prevention of sudden cardiac death due to idiopathic ventricular fibrillation. Subsequently, he was readmitted for lead extraction because of d...
12,704
Outcome after implantation of a cardioverter-defibrillator in patients with Brugada syndrome: a multicenter study-part 2.
Implantable cardioverter-defibrillator indications in Brugada syndrome remain controversial, especially in asymptomatic patients. Previous outcome data are limited by relatively small numbers of patients or short follow-up durations. We report the outcome of patients with Brugada syndrome implanted with an implantable ...
12,705
Preoperative cardiac evaluation by dipyridamole thallium-201 myocardial perfusion scan provides no benefit in patients with abdominal aortic aneurysm.
The purpose of the present study was to evaluate the benefits of a preoperative dipyridamole thallium-201 myocardial perfusion scan in patients undergoing abdominal aortic aneurysm (AAA) repair.</AbstractText>We retrospectively reviewed findings in a prospectively collected database of patients undergoing open or endov...
12,706
Trapped platelets activated in ischemia initiate ventricular fibrillation.
We tested the hypothesis that ischemia-induced ventricular fibrillation (VF) is facilitated by platelets, trapped regionally in the ischemic zone and activated to release arrhythmogenic secretome.</AbstractText>In a randomized study in blood-free, buffer-perfused isolated rat hearts, ischemic zone territory (34&#xb1;1%...
12,707
Significance of inducible very fast ventricular tachycardia (cycle length 200-230 ms) after early reperfusion for ST-segment-elevation myocardial infarction.
Electrophysiological study (EPS) after myocardial infarction may have a role in identifying patients at risk of sudden cardiac death. It has been shown previously that inducible very fast ventricular tachycardia (VT; cycle length [CL], 200-230 ms) is predictive of arrhythmia recurrence; however, its significance early ...
12,708
Prevalence of atrial arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy.
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy, characterized by right ventricular dysfunction and ventricular arrhythmias. Limited information is available concerning atrial arrhythmias in ARVD/C.</AbstractText>The purpose of this study was to characterize spontaneous...
12,709
The incidence, pattern, and prognostic value of left ventricular myocardial scar by late gadolinium enhancement in patients with atrial fibrillation .
This study sought to identify the frequency, pattern, and prognostic significance of left ventricular (LV) late gadolinium enhancement (LGE) in patients with atrial fibrillation (AF).</AbstractText>There are limited data on the presence, pattern, and prognostic significance of LV myocardial fibrosis in patients with AF...
12,710
Treatment of monitored out-of-hospital ventricular fibrillation and pulseless ventricular tachycardia utilising the precordial thump.
Few studies have described the value of the precordial thump (PT) as first-line treatment of monitored out-of-hospital cardiac arrest (OHCA) from ventricular fibrillation and pulseless ventricular tachycardia (VF/VT).</AbstractText>Patient data was extracted from the Victorian Ambulance Cardiac Arrest Registry (VACAR) ...
12,711
Three-dimensional color Doppler echocardiographic quantification of tricuspid regurgitation orifice area: comparison with conventional two-dimensional measures.
Three-dimensional (3D) color Doppler echocardiography (CDE) provides directly measured vena contracta area (VCA). However, a large comprehensive 3D color Doppler echocardiographic study with sufficiently severe tricuspid regurgitation (TR) to verify its value in determining TR severity in comparison with conventional q...
12,712
Valve replacement surgery for older individuals with preoperative atrial fibrillation: the effect of prosthetic valve choice and surgical ablation.
Prosthetic valve type selection combined with surgical ablation during left-sided heart valve replacement in older individuals with atrial fibrillation remains controversial.</AbstractText>A total of 573 patients aged 60 years or older (median, 65; range, 60-84) who underwent left-sided valve replacement surgery in the...
12,713
Targeted ablation at stable atrial fibrillation sources improves success over conventional ablation in high-risk patients: a substudy of the CONFIRM Trial.
Pulmonary vein (PV) isolation has disappointing results in patients with obesity, heart failure, obstructive sleep apnea (OSA) and enlarged left atria (LA), for unclear reasons. We hypothesized that these comorbidities may cause higher numbers or non-PV locations of atrial fibrillation (AF) sources, where targeted sour...
12,714
Near-fatal myocarditis complicating typhoid fever in a traveler returning from Nepal.
We report a 27-year-old traveler who returned from Nepal suffering from typhoid fever. His disease was complicated by life-threatening myocarditis and ventricular fibrillation, a rare manifestation in travelers.
12,715
Drug-induced Brugada syndrome by noncardiac agents.
Drug-induced Brugada syndrome (BrS) represents a great challenge for the prescribing clinicians as well as for those involved in the development of novel pharmaceuticals and in the regulatory bodies responsible with monitoring drug safety. Apart from well-known cardiac agents (mainly Class I antiarrhythmics), an increa...
12,716
Late sodium current inhibition: the most promising antiarrhythmic principle in the near future?
Ranolazine has primarily been developed and so far approved as an antianginal drug. However, it also has potentially interesting and relevant antiarrhythmic properties. Its antiarrhythmic effects are mainly based on the blockade of sodium currents, in particular of the late sodium current. Experimental and clinical stu...
12,717
Bispectral index as a possible early marker of cerebral hypoperfusion.
We report a case of unexplained transient ventricular fibrillation in a child with ventricular septal defect (VSD) scheduled for VSD closure. The bispectral index (BIS) values dropped within 15s of transient cardiac arrest and it showed recovery within 15 s of restoration of circulation. Monitoring BIS during surgery, ...
12,718
An autopsy case of tako-tsubo cardiomyopathy presenting ventricular tachycardia after pacemaker implantation.
We herein report a rare autopsy case of tako-tsubo cardiomyopathy (TTC) presenting ventricular tachycardia after pacemaker implantation. A 69-year-old male received a dual-chamber pacemaker implantation for complete atrioventricular block. He had no chest symptoms after the operation. Three days later, he developed sev...
12,719
Combination of asystole and sinus arrest with junctional escape rhythm seen in Takotsubo cardiomyopathy: A case report.
Takotsubo cardiomyopathy (TCM) is characterized by a transient depression of contractile function of mid and/or apical segments of the left ventricle with compensatory hyperkinesis of the basal segment. It leads to ballooning of the apex in systole, resembling an octopus trap, hence the name. There have been many diffe...
12,720
Cognitive impairment after appropriate implantable cardioverter-defibrillator therapy for ventricular fibrillation.
Short periods of cerebral ischaemia during ventricular defibrillation testing may be associated with neuropsychological impairment. However, the impact of out-of-hospital ventricular fibrillation (VF) converted by implantable cardioverter-defibrillator (ICD) shock on cognitive functioning is unknown.</AbstractText>To a...
12,721
Impact of pulmonary vein isolation on obstructive sleep apnea in patients with atrial fibrillation.
Obstructive sleep apnea (OSA) has been identified as associated with the onset and propagation of atrial fibrillation (AF) and predicts recurrences of AF after pulmonary vein isolation (PVI). Vice versa, it has never been investigated whether PVI influences OSA. However, it has been controversial whether a restored atr...
12,722
Electromechanical delay detected by tissue Doppler echocardiography is associated with the frequency of attacks in patients with lone atrial fibrillation.
Our main purpose in this study is to compare atrial (inter-atrial, intra-left atrial, intra-right atrial) electromechanical delays of patients with lone atrial fibrillation (LAF) with healthy individuals and examine the relationship of annual LAF attack frequency.</AbstractText>32 entirely healthy individuals and 32 pa...
12,723
Beta-blockade and A1-adenosine receptor agonist effects on atrial fibrillatory rate and atrioventricular conduction in patients with atrial fibrillation.
Reduced irregularity of RR intervals in permanent atrial fibrillation (AF) has been associated with poor outcome. It is not fully understood, however, whether modification of atrioventricular (AV) conduction using rate-control drugs affects RR variability and irregularity measures. We aimed at assessing whether atrial ...
12,724
Ablation of atrial fibrillation in Brugada syndrome patients with an implantable cardioverter defibrillator to prevent inappropriate shocks resulting from rapid atrial fibrillation.
Inappropriate shocks resulting from atrial tachyarrhythmias are highly problematic for patients with an implantable cardioverter defibrillator (ICD). We aimed to determine the effectiveness of catheter ablation of atrial fibrillation (AF) in preventing inappropriate shocks due to rapid AF in patients diagnosed with Bru...
12,725
Temporary resolution of chronic atrial fibrillation after cardiac surgery and the prolongation of ventricular repolarization.
Chronic atrial fibrillation may temporarily resolve after cardiac surgery. Prolongation of the ventricular repolarization period may be the electrophysiological background for this phenomenon.</AbstractText>The aim of the study was to assess the association between resolution of atrial fibrillation and changes in the d...
12,726
[Effectiveness of simultaneous cardiac resynchronization therapy in surgical valvular patients with severe heart failure].
Cardiac resynchronization therapy (CRT)has been accepted broadly as an alternative to medical treatment in managing severe heart failure patients. Despite advance in CRT, the presence of a significant valvular heart disease was currently specific exclusion criteria and a response to this therapy remains unclear. The pu...
12,727
Complex atrial arrhythmias as first manifestation of catecholaminergic polymorphic ventricular tachycardia: an unusual course in a patient with a new mutation in ryanodine receptor type 2 gene.
Catecholaminergic polymorphic ventricular tachycardia is a rare life-threatening arrhythmogenic disorder. An association with paroxysmal atrial fibrillation and other atrial arrhythmias has been described, but in all published cases the initial manifestation of the disease was ventricular arrhythmia. This is the first ...
12,728
Echocardiography in newly diagnosed atrial fibrillation patients: a systematic review and economic evaluation.
To investigate the clinical effectiveness and cost-effectiveness of transthoracic echocardiography (TTE) in all patients who are newly diagnosed with atrial fibrillation (AF).</AbstractText>Narrative synthesis reviews were conducted on the prognostic and diagnostic accuracy of TTE for, and prevalence of, pathologies in...
12,729
[A case of large tracheoesophageal fistula after repair of the right discending aortic arch].
A 77-year-old woman with right aortic arch was diagnosed as aortic dissection (De Bakey IIIb) and hospitalized for conservative treatment. But, her respiratory condition deteriorated due to tracheal stenosis with aortic dissection. Surgical graft replacement of the descending aorta was performed to release tracheal ste...
12,730
Caring for patients receiving therapeutic hypothermia post cardiac arrest in the intensive care unit.
Survivors of ventricular fibrillation cardiac arrest have poor and often devastating neurological outcomes despite advances in resuscitation techniques and services (Bernard et al., 2002; Collins &amp; Samworth, 2008). In an effort to increase survival rates, improve neurological outcomes and reduce mortality for survi...
12,731
Waveform analysis-guided treatment versus a standard shock-first protocol for the treatment of out-of-hospital cardiac arrest presenting in ventricular fibrillation: results of an international randomized, controlled trial.
Ventricular fibrillation (VF) waveform properties have been shown to predict defibrillation success and outcomes among patients treated with immediate defibrillation. We postulated that a waveform analysis algorithm could be used to identify VF unlikely to respond to immediate defibrillation, allowing selective initial...
12,732
Safety and efficacy of a totally subcutaneous implantable-cardioverter defibrillator.
The most frequent complications associated with implantable cardioverter-defibrillators (ICDs) involve the transvenous leads. A subcutaneous implantable cardioverter-defibrillator (S-ICD) has been developed as an alternative system. This study evaluated the safety and effectiveness of the S-ICD System (Cameron Health/B...
12,733
Association between renal function, diastolic dysfunction, and postoperative atrial fibrillation following cardiac surgery.
Renal dysfunction is associated with a higher rate of atrial fibrillation in clinical practice. This study investigated the associations between renal function, left ventricular (LV) diastolic dysfunction, and postoperative atrial fibrillation (POAF).</AbstractText>A total of 265 consecutive patients who underwent card...
12,734
Imaging techniques in electrophysiology and implantable device procedures: results of the European Heart Rhythm Association survey.
The purpose of this European Heart Rhythm Association (EHRA) survey is to assess the implementation and use of imaging techniques in cardiac electrophysiology (EP) and device procedures across European cardiovascular centres. Forty European centres, all members of the EHRA EP research network, responded to this survey....
12,735
Bisoprolol reversed small conductance calcium-activated potassium channel (SK) remodeling in a volume-overload rat model.
A recent study indicated that apamin-sensitive current (I KAS, mediated by apamin-sensitive small conductance calcium-activated potassium channels subunits) density significantly increased in heart failure and led to recurrent spontaneous ventricular fibrillation. While the underlying molecular correlation with SK chan...
12,736
Impact of the right ventricular lead position on clinical outcome and on the incidence of ventricular tachyarrhythmias in patients with CRT-D.
Data on the impact of right ventricular (RV) lead location on clinical outcome and ventricular tachyarrhythmias in cardiac resynchronization therapy with defibrillator (CRT-D) patients are limited.</AbstractText>To evaluate the impact of different RV lead locations on clinical outcome in CRT-D patients enrolled in the ...
12,737
New image processing and noise reduction technology allows reduction of radiation exposure in complex electrophysiologic interventions while maintaining optimal image quality: a randomized clinical trial.
Despite their carcinogenic potential, X-rays remain indispensable for electrophysiologic (EP) procedures.</AbstractText>The purpose of this study was to evaluate the dose reduction and image quality of a novel X-ray technology using advanced image processing and dose reduction technology in an EP laboratory.</AbstractT...
12,738
Arrhythmias in patients with acute coronary syndrome in the first 24 hours of hospitalization.
In patients with acute coronary syndrome (ACS), we sought to: 1) describe arrhythmias during hospitalization, 2) explore the association between arrhythmias and patient outcomes, and 3) explore predictors of the occurrence of arrhythmias.</AbstractText>In a prospective sub-study of the IMMEDIATE AIM study, we analyzed ...
12,739
Signal integral for optimizing the timing of defibrillation.
The possibility of successful defibrillation decreases with an increased duration of ventricular fibrillation (VF). Futile electrical shocks are inversely correlated with myocardial contractile function and long-term survival. Previous studies have demonstrated that various ECG waveform analyses predict the success of ...
12,740
Comparative analysis of clinical, electrocardiographic, angiographic and echocardiographic data of indigenous and non-indigenous residents of Yakutia with coronary artery atherosclerosis.
The aim of the study is to compare clinical, angiographic, electrocardiographic, echocardiographic data between indigenous and non-indigenous residents of Yakutia.</AbstractText>We performed cross-sectional analysis of the Registry of Selective Coronary Angiography (SCAG) of the Yakutsk Republican Hospital for the peri...
12,741
Relationship between seizure episode and sudden cardiac arrest in patients with epilepsy: a community-based study.
Among patients with epilepsy, sudden cardiac arrest (SCA) is a major cause of death. It is commonly thought that SCA in epilepsy occurs after a seizure, though the strength of evidence supporting this is limited. We sought to evaluate the relationship between seizures and SCA in patients with epilepsy.</AbstractText>Fr...
12,742
Inadvertently Developed Ventricular Fibrillation during Electrophysiologic Study and Catheter Ablation: Incidence, Cause, and Prognosis.
Ventricular fibrillation (VF) can inadvertently occur during electrophysiologic study (EPS) or catheter ablation. We investigated the incidence, cause, and progress of inadvertently developed VF during EPS and catheter ablation.</AbstractText>We reviewed patients who had developed inadvertent VF during EPS or catheter ...
12,743
Longitudinal changes in intracardiac repolarization lability in patients with implantable cardioverter-defibrillator.
While it is known that elevated baseline intracardiac repolarization lability is associated with the risk of fast ventricular tachycardia (FVT)/ventricular fibrillation (VF), the effect of its longitudinal changes on the risk of FVT/VF is unknown.</AbstractText>Near-field (NF) right ventricular (RV) intracardiac electr...
12,744
The SCN5A mutation A1180V is associated with electrocardiographic features of LQT3.
Mutations of the SCN5A gene are associated with several arrhythmic syndromes including the Brugada syndrome, conduction disease, long QT syndrome type 3 (LQT3), atrial fibrillation, and dilated cardiomyopathy. We report LQT3 associated with an A1180V cardiac sodium channel mutation, previously associated with cardiac c...
12,745
Ventricular activity cancellation in electrograms during atrial fibrillation with constraints on residuals' power.
During atrial fibrillation (AF), cancellation of ventricular activity from atrial electrograms (AEG) is commonly performed by template matching and subtraction (TMS): a running template, built in correspondence of QRSs, is subtracted from the AEG to uncover atrial activity (AA). However, TMS can produce poor cancellati...
12,746
Characteristics of patients that experience cardiopulmonary arrest following aortic dissection and aneurysm.
The aim of this study is to investigate the characteristics of patients experience cardiopulmonary arrest (CPA) in the acute phase following aortic dissection and aneurysm (AD).</AbstractText>Patients who were transported to this department from January 2005 to December 2010 and subsequently diagnosed with AD were incl...
12,747
Functional mitral regurgitation after a first non-ST segment elevation acute coronary syndrome: very-long-term follow-up, prognosis and contribution to left ventricular enlargement and atrial fibrillation development.
To assess the relationship between functional mitral regurgitation (MR) after a non-ST segment elevation acute coronary syndrome (NSTSEACS) and long-term prognosis, ventricular remodelling and further development of atrial fibrillation (AF), since functional MR is common after myocardial infarction.</AbstractText>Prosp...
12,748
Ringless alfieri mitral valve repair for significant ischemic mitral regurgitation with coronary artery bypass grafting.
Ischemic mitral regurgitation (IMR) is associated with diminished survival prospects. Ringless edge-to-edge mitral valve repair is usually performed in association with coronary artery bypass grafting (CABG). In this report, we present our early results for ringless edge-to-edge repair and concomitant CABG.</AbstractTe...
12,749
A comparison of clinical characteristics and long-term prognosis in asymptomatic and symptomatic patients with first-diagnosed atrial fibrillation: the Belgrade Atrial Fibrillation Study.
To investigate baseline characteristics and long-term prognosis of carefully characterized asymptomatic and symptomatic patients with atrial fibrillation (AF) in a 'real-world' cohort of first-diagnosed non-valvular AF over a 10-year follow-up period.</AbstractText>We conducted an observational, non-interventional, and...
12,750
Acute myocardial infarction and massive pulmonary embolus presenting as cardiac arrest: initial rhythm as a diagnostic clue.
Myocardial infarction (MI) and massive pulmonary embolism (MPE) are common causes of cardiac arrest. We present two cases with similar clinical presentation and EKG findings but different initial rhythms. Case&#x2009;&#x2009;1. A 55-year-old African American male (AAM) was brought to the emergency room (ER) with cardia...
12,751
Fragmented QRS predicts cardiovascular death of patients with structural heart disease and inducible ventricular tachyarrhythmia.
Fragmented QRS (fQRS) can predict cardiac events, and inducible ventricular tachycardia/fibrillation (VT/VF) is a known high-risk factor for arrhythmic death. However, whether fQRS is a predictor of cardiac events in patients with inducible VT/VF is unknown. We aimed to evaluate whether fQRS is a predictor of cardiac e...
12,752
The prognostic impact of pre-implantation hyponatremia on morbidity and mortality among patients with left ventricular dysfunction and implantable cardioverter-defibrillators.
Hyponatremia is commonly observed among patients with left ventricular (LV) dysfunction and is a marker for adverse outcomes. We aimed to determine the prognostic significance of pre-implant hyponatremia on the outcomes of death, acute decompensated heart failure (ADHF) and appropriate implantable cardioverter-defibril...
12,753
Clinical examination for prognostication in comatose cardiac arrest patients.
To build new algorithms for prognostication of comatose cardiac arrest patients using clinical examination, and investigate whether therapeutic hypothermia influences the value of the clinical examination.</AbstractText>From 2000 to 2007, 500 consecutive patients in non-traumatic coma were prospectively enrolled, 200 o...
12,754
[Cardiac resynchronization therapy in patients with permanent atrial fibrillation].
In our study we compared effect of cardiac resynchronization therapy (CRT) in chronic heart failure (CHF) patients with permanent atrial fibrillation (AF) and patients with sinus rhythm. Special feature of our work was that patients with permanent atrial fibrillation didnt have obligatory ablation of atrio-ventricular ...
12,755
[Protective action of ethylglutathione at hypoxia-reoxygenation of the heart: role of glucose].
Glutathione is the main redox buffer in cardiomyocytes. The action of ethylglutathione possessing antioxidant properties on functional disorders evoked by 30-minute hypoxia of the isolated rat heart with subsequent reoxygenation has been studied. In control experiments, the presence of glucose (11 mM) in hypoxic perfus...
12,756
Effects of high-dose radiotherapy on implantable cardioverter defibrillators: an in vivo porcine study.
Although the effects of radiotherapy (RT) on implantable cardioverter defibrillators (ICDs) have been studied in vitro, and some information has been gathered from case reports and series, no in vivo experiments have previously been performed.</AbstractText>In vivo effects of photon RT applied directly to five modern I...
12,757
Electrophysiology of T-wave alternans: mechanisms and pharmacologic influences.
Extensive experimental evidence indicates a fundamental link between T-wave alternans (TWA) and arrhythmogenesis. Diverse physiologic and pathophysiologic influences alter TWA magnitude in parallel with their effects on vulnerability to ventricular tachyarrhythmias. Specifically, interventions that impede intracellular...
12,758
Transmural IK(ATP) heterogeneity as a determinant of activation rate gradient during early ventricular fibrillation: mechanistic insights from rabbit ventricular models.
Activation rate (AR) gradients develop during ventricular fibrillation (VF), with the highest AR on the surface near Purkinje system (PS) terminals (endocardium in humans and rabbits and epicardium in pigs). The application of glibenclamide to block adenosine triphosphate (ATP)-sensitive potassium current (IK(ATP)) bef...
12,759
Impact of atrial fibrillation on early complications and one year-survival after cardioverter defibrillator implantation: results from the German DEVICE registry.
Outcome data of patients with implantable cardioverter defibrillators (ICD) and atrial fibrillation (AF) are conflicting. The German DEVICE registry aims to add further information on this particular cohort.</AbstractText>The German DEVICE registry is a nationwide prospective multicenter database of ICD implantations. ...
12,760
Clinical efficacy of dofetilide for the treatment of atrial tachyarrhythmias in adults with congenital heart disease.
Atrial tachyarrhythmias (AT) including atrial fibrillation (AF), atrial flutter (AFL), and atrial tachycardia represent a clinical challenge in the adult with congenital heart disease (CHD). Dofetilide (D) is a rapidly activating delayed rectifier potassium channel (IKr) blocker effective in pharmacological conversion ...
12,761
Prophylactic and therapeutic effects of garlic extract on Nerium oleander-induced arrhythmia: a new approach to antiarrhythmic therapy in an ovine model.
Oleander is a potent cardiotoxic plant and is a common cause of poisoning in human and animals. There is no affordable and cost-effective treatment for oleander poisoning. Objective. To evaluate the prophylactic and therapeutic effects of garlic extract (Allium sativum) on Nerium oleander (a potent cardiotoxic plant) i...
12,762
A comparison of survival following out-of-hospital cardiac arrest in Sydney, Australia, between 2004-2005 and 2009-2010.
To determine whether survival following out-of- hospital cardiac arrest (OHCA) in Sydney, Australia, improved between 2004-2005 and 2009-2010, and whether there was a change in incidence of OHCA.</AbstractText>Retrospective study using the Ambulance Service of New South Wales and NSW Registry of Births, Deaths and Marr...
12,763
Hyperoxia in the intensive care unit and outcome after out-of-hospital ventricular fibrillation cardiac arrest.
Laboratory and clinical studies have suggested that hyperoxia early after resuscitation from cardiac arrest may increase neurological injury and worsen outcome. Previous clinical studies have been small or have not included relevant prehospital data. We aimed to determine in a larger cohort of patients whether hyperoxi...
12,764
Association between early surgical intervention vs watchful waiting and outcomes for mitral regurgitation due to flail mitral valve leaflets.
The optimal management of severe mitral valve regurgitation in patients without class I triggers (heart failure symptoms or left ventricular dysfunction) remains controversial in part due to the poorly defined long-term consequences of current management strategies. In the absence of clinical trial data, analysis of la...
12,765
Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias.
Human (h) pluripotent stem cells (PSC) such as embryonic stem cells (ESC) can be directed into cardiomyocytes (CMs), representing a potential unlimited cell source for disease modeling, cardiotoxicity screening and myocardial repair. Although the electrophysiology of single hESC-CMs is now better defined, their multi-c...
12,766
The relationship between atrial septal aneurysm and autonomic dysfunction.
Systemic thromboembolism is a serious, major complication in patients with an atrial septal aneurysm (ASA). Atrial dysfunction resulting from paroxysmal atrial fibrillation is more common in patients with ASA than in the general population. The autonomic nervous system plays an important role in the initiation of atria...
12,767
Electrocardiogram as a screening tool in the general population: a strategic review.
Sudden cardiac death (SCD) is a major public health concern, accounting for 400,000 deaths in the US each year. Clinical and autopsy studies have consistently demonstrated a predominant, common pathophysiology in Western populations, showing that the most common electrophysiological mechanism of SCD is ventricular fibr...
12,768
Atrial fibrillation with rapid ventricular response resulting from low-voltage electrical injury.
Cardiac dysrhythmias after electrical injury have been reported previously, however, atrial fibrillation after low-voltage electrical injury is extremely rare. We present a case of atrial fibrillation with rapid ventricular response resulting from a low-voltage electrical injury.</AbstractText>A 24-year-old active duty...
12,769
"Rescue" ablation of electrical storm in arrhythmogenic right ventricular cardiomyopathy in pregnancy.
Radiofrequency ablation (RFCA) became a treatment of choice in patients with recurrent ventricular tachycardia, ventricular fibrillation, and appropriate interventions of implanted cardioverter-defibrillator (ICD), however, electrical storm (ES) ablation in a pregnant woman has not yet been reported.</AbstractText>We d...
12,770
Exercise training and implantable cardioverter-defibrillator shocks in patients with heart failure: results from HF-ACTION (Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing).
The purpose of this study was to determine whether exercise training is associated with an increased risk of implantable cardioverter-defibrillator (ICD) therapy in patients with heart failure (HF).</AbstractText>Few data are available regarding the safety of exercise training in patients with ICDs and HF.</AbstractTex...
12,771
Cardiac arrest at exercise facilities: implications for placement of automated external defibrillators.
This study sought to characterize the relative frequency, care, and survival of sudden cardiac arrest in traditional indoor exercise facilities, alternative indoor exercise sites, and other indoor sites.</AbstractText>Little is known about the relative frequency of sudden cardiac arrest at traditional indoor exercise f...
12,772
Inhibition of I(f) in the atrioventricular node as a mechanism for dronedarone's reduction in ventricular rate during atrial fibrillation.
In clinical trials, dronedarone lowers ventricular rate during atrial fibrillation (AF). This agent was recently demonstrated to inhibit If in the sinoatrial node.</AbstractText>The purpose of this study was to examine whether dronedarone inhibits If at the atrioventricular (AV) node to reduce ventricular rate during A...
12,773
Low-amplitude, left vagus nerve stimulation significantly attenuates ventricular dysfunction and infarct size through prevention of mitochondrial dysfunction during acute ischemia-reperfusion injury.
Right cervical vagus nerve stimulation (VNS) provides cardioprotective effects against acute ischemia-reperfusion injury in small animals. However, inconsistent findings have been reported.</AbstractText>To determine whether low-amplitude, left cervical VNS applied either intermittently or continuously imparts cardiopr...
12,774
Association between obesity and postoperative atrial fibrillation in patients undergoing cardiac operations: a systematic review and meta-analysis.
In a systematic review and random-effects meta-analysis, we evaluated whether obesity is associated with postoperative atrial fibrillation (POAF) in patients undergoing cardiac operations. We selected 18 observational studies until December 2011 that excluded patients with preoperative AF (n=36,147). Obese patients had...
12,775
Severe sepsis and septic shock in patients with pre-existing non-cardiac pulmonary hypertension: contemporary management and outcomes.
To review treatment and outcomes of septic shock in patients with pulmonary hypertension (PH) managed at a tertiary care institution.</AbstractText><AbstractText Label="DESIGN, SETTING AND PATIENTS" NlmCategory="METHODS">We identified consecutive patients with non-cardiac PH (non-Group 2 in the World Health Organizatio...
12,776
Curvature analysis of cardiac excitation wavefronts.
We present the Spiral Classification Algorithm (SCA), a fast and accurate algorithm for classifying electrical spiral waves and their associated breakup in cardiac tissues. The classification performed by SCA is an essential component of the detection and analysis of various cardiac arrhythmic disorders, including vent...
12,777
A review of the confirmation algorithm and related timing cycles of St. Jude ICDs.
The confirmation algorithm of implantable cardioverter-defibrillators (ICDs) functioning in the uncommitted mode verifies the presence of a continuing tachyarrhythmia during or following charging of the capacitor. Confirmation is usually applied in relation to the first shock. The details of the normal reconfirmation p...
12,778
Value of early cardiovascular magnetic resonance for the prediction of adverse arrhythmic cardiac events after a first noncomplicated ST-segment-elevation myocardial infarction.
Infarct size (IS) determined by cardiac magnetic resonance (CMR) has proven an additional value, on top of left ventricular ejection fraction (LVEF), in prediction of adverse arrhythmic cardiac events (AACEs) in chronic ischemic heart disease. Its value soon after an acute ST-segment-elevation myocardial infarction rem...
12,779
Storms of ventricular fibrillation responsive to isoproterenol in an idiopathic ventricular fibrillation patient demonstrating complete right bundle branch block.
A 45-year-old male was admitted to our hospital after successful resuscitation of cardiac arrest. Ventricular fibrillation (VF) had occurred during breakfast and was defibrillated by an automated external defibrillator operated by emergency medical service staff. On admission, his ECG demonstrated complete right bundle...
12,780
Methadone-induced Torsades de pointes.
Torsades de pointes is a polymorphic ventricular tachycardia that can quickly evolve into ventricular fibrillation and sudden death. This arrhythmia often occurs secondary to medication- induced cardiac repolarization dysfunction with resultant prolonged QTc interval on ECG. Numerous medications can predispose patients...
12,781
Amiodarone inhibits apamin-sensitive potassium currents.
Apamin sensitive potassium current (I KAS), carried by the type 2 small conductance Ca(2+)-activated potassium (SK2) channels, plays an important role in post-shock action potential duration (APD) shortening and recurrent spontaneous ventricular fibrillation (VF) in failing ventricles.</AbstractText>To test the hypothe...
12,782
Early mortality in prophylactic implantable cardioverter-defibrillator recipients: development and validation of a clinical risk score.
To reduce sudden cardiac death, implantable cardioverter-defibrillators (ICDs) are indicated in patients with ischaemic and non-ischaemic dilated cardiomyopathy and a left ventricular ejection fraction (LVEF) &#x2264;35%. Current guidelines do not recommend device therapy in patients with a life expectancy &lt;1 year s...
12,783
The impact of haemodialysis on the outcomes of catheter ablation in patients with paroxysmal atrial fibrillation.
The outcomes of catheter ablation (CA) in patients with paroxysmal atrial fibrillation (PAF) who are undergoing haemodialysis (HD) have not been fully elucidated. This study aimed to determine the impact of HD on CA outcome in these patients.</AbstractText>We examined 1364 consecutive PAF patients (mean age, 61 &#xb1; ...
12,784
Surgical approach to intramyocardial administration of bone marrow stem cells in an animal model.
The aim of the study was to evaluate the surgical approach to intramyocardial (i.m.) injection of Bone Marrow Stem Cells (BMSCs) in a pre-clinical model and its complications.</AbstractText>In New Zealand rabbits an ischemia reperfusion injury lasting 20 min was induced by temporary ligation of anterior descending coro...
12,785
[Clinical evaluation of intraoperative cardiac output measurement by a new arterial pressure waveform analysis method( FloTrac/Vigileo) in open heart surgery].
We retrospectively evaluated the initial clinical experience of intraoperative cardiac output measurement by a new arterial pressure-based cardiac output (APCO:FloTrac/Vigileo) analysis in patients undergoing open heart surgery. Thirty-two patients (mean age 76.4, range 59 to 90)who underwent cardiac surgery under card...
12,786
Efficacy, safety, and outcomes of catheter ablation of atrial fibrillation in patients with heart failure with preserved ejection fraction.
This study sought to investigate the efficacy and safety of catheter ablation for atrial fibrillation (AF) in patients with heart failure with preserved ejection fraction (HFPEF).</AbstractText>AF is a precipitating factor for clinical deterioration of HFPEF.</AbstractText>Catheter ablation for AF was performed in a co...
12,787
Wearable cardioverter-defibrillator use in patients perceived to be at high risk early post-myocardial infarction.
The aim of this study was to describe usage of the wearable cardioverter-defibrillator (WCD) during mandated waiting periods following myocardial infarction (MI) for patients perceived to be at high risk for sudden cardiac arrest (SCA).</AbstractText>Current device guidelines and insurance coverage require waiting peri...
12,788
Ventricular fibrillation associated with J-wave manifestation following pericarditis after catheter ablation for paroxysmal atrial fibrillation.
We present a patient with ventricular fibrillation (VF) associated with J-wave manifestation following pericarditis after catheter ablation of paroxysmal atrial fibrillation (AF). The premature ventricular contraction induced VF with J-waves in the inferior leads 2 days after the procedure. The patient's juvenile onset...
12,789
Idiopathic ventricular arrhythmias detected by an implantable loop recorder in a child with exercise-induced syncope.
Syncope is common in the general population. Despite extensive evaluation, including tilt-table testing and electrophysiologic studies, approximately 30% of cases of recurrent syncope remain unexplained. An implantable loop recorder can be used for diagnosis when recurrent syncope has an idiopathic cause. We present th...
12,790
Coronary intervention on a moving target: a case report and procedural considerations.
Cardiac arrest carries a considerable mortality. Among survivors, the incidence of neurological dysfunction is considerable. Coronary disease is a major cause of cardiac arrest and early and effective resuscitation is related to outcome. We report for the first time a case of successful coronary angiography and primary...
12,791
Identification of clinical risk factors of atrial fibrillation in congestive heart failure.
Factors associated with the development of atrial fibrillation (AF) in general population have been described, but it is still unknown whether the same risk factors apply to heart failure (HF) patients. The aim of this study was to identify clinical factors related to various forms of AF in HF patients.</AbstractText>T...
12,792
An unusual intracardiac electrogram showing cause for false electrical discharge from an ICD.
We describe a rare case of inappropriate implantable cardioverter defibrillator (ICD) therapy due to false sensing of electromechanical interference from diathermy as 'ventricular fibrillation (VF)'. This occurred during surgical removal of sternal wires under general anaesthesia. Postsurgical interrogation of ICD reve...
12,793
Cellular mechanisms underlying the effects of milrinone and cilostazol to suppress arrhythmogenesis associated with Brugada syndrome.
Brugada syndrome is an inherited disease associated with vulnerability to ventricular tachycardia and sudden cardiac death in young adults. Milrinone and cilostazol, oral phosphodiesterase (PDE) type III inhibitors, have been shown to increase L-type calcium channel current (ICa) and modestly increase heart rate by ele...
12,794
Robotics in cardiac surgery: past, present, and future.
Robotic cardiac operations evolved from minimally invasive operations and offer similar theoretical benefits, including less pain, shorter length of stay, improved cosmesis, and quicker return to preoperative level of functional activity. The additional benefits offered by robotic surgical systems include improved dext...
12,795
Cardiogenic pulmonary oedema: alarmingly poor long term prognosis. Analysis of risk factors.
Acute heart failure (AHF) is a life-threatening condition associated with poor prognosis.</AbstractText>To investigate the long term prognosis and identify prognostic factors among patients who were discharged after an episode of cardiogenic pulmonary oedema.</AbstractText>We enrolled 84 patients (M: 56%, n = 47) who w...
12,796
Detection of a spontaneous pulse in photoplethysmograms during automated cardiopulmonary resuscitation in a porcine model.
Reliable, non-invasive detection of return of spontaneous circulation (ROSC) with minimal interruptions to chest compressions would be valuable for high-quality cardiopulmonary resuscitation (CPR). We investigated the potential of photoplethysmography (PPG) to detect the presence of a spontaneous pulse during automated...
12,797
[Early cardiovascular complications post lung transplantation].
To observe the early cardiovascular complications of patients underwent lung transplantation.</AbstractText>The clinical records of 73 patients who underwent lung transplantation in Wuxi People's Hospital from September 2002 to September of 2010 were retrospectively analyzed. All patients were transferred to intensive ...
12,798
Continuous monitoring of cardiac rhythms in left ventricular assist device patients.
Monitoring of cardiac rhythms is of major importance in the treatment of heart failure patients with left ventricular assist devices (LVADs) implanted. A continuous surveillance of these rhythms could improve out-of-hospital care in these patients. The aim of this study was to investigate cardiac rhythms using availabl...
12,799
Impact of severe tricuspid regurgitation on long term survival.
Tricuspid regurgitation (TR) is a common echocardiographic finding, which often accompanies left sided valve disease. Data on mortality and morbidity in patients with severe TR are limited.</AbstractText>We sought to assess the outcome of patients with severe TR with the hypothesis that significant TR adversely impacts...