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12,500 | Simultaneous double coronary thrombosis in a 47-year-old male patient with acute myocardial infarction. | Male, 47 FINAL DIAGNOSIS: Acute myocardial infarction Symptoms: Chest pain Medication: - Clinical Procedure: - Specialty: Cardiology.</AbstractText>Unusual clinical course.</AbstractText>Double myocardial infarction involving two culprit major vessels is a rarely reported presentation with high incidence of mortality.<... |
12,501 | Dual-site right ventricular and left ventricular pacing in a patient with left ventricular systolic dysfunction and atrial fibrillation using a standard CRT-D device. | In patients undergoing cardiac resynchronization therapy with defibrillator (CRT-D) implantation for left ventricular systolic dysfunction (LVSD) accompanied by permanent atrial fibrillation (AF), generally, the unused atrial port is plugged at device implantation. We describe an alternative use for the atrial-port in ... |
12,502 | Left ventricular diastolic function is associated with symptom status in severe aortic valve stenosis. | In aortic valve stenosis (AS), the occurrence of heart failure symptoms does not always correlate with severity of valve stenosis and left ventricular (LV) function. Therefore, we tested the hypothesis that symptomatic patients with AS have impaired diastolic, longitudinal systolic function, and left atrial dilatation ... |
12,503 | Experimental cardiac arrest treatment with adrenaline, vasopressin, or placebo. | The effect of vasoconstrictors in prolonged cardiopulmonary resuscitation (CPR) has not been fully clarified.</AbstractText>To evaluate adrenaline and vasopressin pressure effect, and observe the return of spontaneous circulation (ROSC).</AbstractText>A prospective, randomized, blinded, and placebo-controlled study. Af... |
12,504 | Preferred tools and techniques for implantation of cardiac electronic devices in Europe: results of the European Heart Rhythm Association survey. | The aim of this European Heart Rhythm Association (EHRA) survey was to assess clinical practice in relation to the tools and techniques used for cardiac implantable electronic devices procedures in the European countries. Responses to the questionnaire were received from 62 members of the EHRA research network. The sur... |
12,505 | Weather and triggering of ventricular arrhythmias in patients with implantable cardioverter-defibrillators. | Outdoor ambient weather has been hypothesized to be responsible for the seasonal distribution of cardiac arrhythmias. Because people spend most of their time indoors, we hypothesized that weather-related arrhythmia risk would be better estimated using an indoor measure or an outdoor measure that correlates well with in... |
12,506 | Does atrial pacing lead to atrial fibrillation in patients with sick sinus syndrome? Insights from the DANPACE trial. | Paroxysmal atrial fibrillation (AF) is common in patients with sick-sinus syndrome (SSS) and pacemakers leading to morbidity and an increased risk of stroke or death. Previous studies indicate that atrial pacing may precipitate AF. We investigated the relation between atrial pacing and the occurrence of AF during long-... |
12,507 | Relations of plasma total and high-molecular-weight adiponectin to new-onset heart failure in adults ≥65 years of age (from the Cardiovascular Health study). | Adiponectin exhibits cardioprotective properties in experimental studies, but elevated levels have been linked to increased mortality in older adults and patients with chronic heart failure (HF). The adipokine's association with new-onset HF remains less well defined. The aim of this study was to investigate the associ... |
12,508 | Usefulness of N-terminal pro-B-type natriuretic Peptide increase as a marker for cardiac arrhythmia in patients with syncope. | B-type natriuretic peptides (BNPs) have been investigated as biomarkers for risk stratification of patients with syncope. Their concentration can be influenced by age and co-morbidities. In the present study, we compared the change in N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels within 6 hours in patien... |
12,509 | Novel mitral clipping technique overcoming extreme atrial dilatation. | The mitral clipping technique is emerging as a promising new treatment option for severe mitral regurgitation. The device was designed and assessed in intermediate risk populations, which is in contrast to the real world, where most patients are deemed to be at very high risk for open heart surgery. The cardiac anatomy... |
12,510 | Silent cerebral infarcts associated with cardiac disease and procedures. | The occurrence of clinically silent cerebral infarcts (SCIs) in individuals affected by cardiac disease and after invasive cardiac procedures is frequently reported. Indeed, atrial fibrillation, left ventricular thrombus formation, cardiomyopathy, and patent foramen ovale have all been associated with SCIs. Furthermore... |
12,511 | Is health-related quality of life a predictor of hospitalization or mortality among women or men with atrial fibrillation? | Little is known about predictors of mortality or hospitalization in women compared with men in patients with atrial fibrillation (AF). Although there are established gender differences in patients with coronary artery disease (CAD), differences have not been established in AF.</AbstractText>The aim of this study was to... |
12,512 | Detection of atrial electrical and mechanical dysfunction in non-dipper pre-hypertensive subjects. | A relationship between atrial conduction time and hypertension was shown in previous studies. Increased atrial electromechanical intervals used to predict atrial fibrillation by measured tissue Doppler imaging (TDI). So we aimed to search if there was any association between the non-dipping status and atrial electromec... |
12,513 | Impact of atrial fibrillation on exercise capacity in heart failure with preserved ejection fraction: a RELAX trial ancillary study. | Atrial fibrillation (AF) is common among patients with heart failure and preserved ejection fraction (HFpEF), but its clinical profile and impact on exercise capacity remain unclear. RELAX (Phosphodiesterase-5 Inhibition to Improve Clinical Status and Exercise Capacity in HFpEF) was a multicenter randomized trial testi... |
12,514 | Therapeutic strategy using extracorporeal life support, including appropriate indication, management, limitation and timing of switch to ventricular assist device in patients with acute myocardial infarction. | The appropriate indication for, management of and limitations to extracorporeal life support (ECLS) and the timing of a switch to a ventricular assist device (VAD) remain controversial issues in patients with acute myocardial infarction (AMI) complicated with cardiogenic shock or cardiopulmonary arrest. To evaluate and... |
12,515 | Cardiopulmonary involvement in Puumala hantavirus infection. | Hantavirus infections cause potentially life-threatening disease in humans world-wide. Infections with American hantaviruses may lead to hantavirus pulmonary syndrome characterised by severe cardiopulmonary distress with high mortality. Pulmonary involvement in European Puumala hantavirus (PUUV) infection has been repo... |
12,516 | [Immune status of patients with persistent atrial fibrillation and coronary heart disease]. | We estimated the strength of immune response to chlamydial infection in patients with CHD. It was most pronounced in CHD patients with atrial fibrillation (AF). There was close relationship between past chlamydial infection and markers of inflammation (CRP and TNF-alpha). The study demonstrated high prognostic value of... |
12,517 | Prevention of atrial fibrillation by bucindolol is dependent on the beta₁389 Arg/Gly adrenergic receptor polymorphism. | This study assessed the impact of bucindolol, a beta-blocker/sympatholytic agent, on the development of atrial fibrillation (AF) in advanced chronic heart failure with reduced left ventricular ejection fraction (HFREF) patients enrolled in the BEST (Beta-Blocker Evaluation of Survival Trial).</AbstractText>β-bloc... |
12,518 | A century of optocardiography. | In the past decade, optical mapping provided crucial mechanistic insight into electromechanical function and the mechanism of ventricular fibrillation. Therefore, to date, optical mapping dominates experimental cardiac electrophysiology. The first cardiac measurements involving optics were done in the early 1900s using... |
12,519 | Mechanical ventilation during cardiopulmonary resuscitation with intermittent positive-pressure ventilation, bilevel ventilation, or chest compression synchronized ventilation in a pig model. | Mechanical ventilation with an automated ventilator is recommended during cardiopulmonary resuscitation with a secured airway. We investigated the influence of intermittent positive-pressure ventilation, bilevel ventilation, and the novel ventilator mode chest compression synchronized ventilation, a pressure-controlled... |
12,520 | Shorter minimum p-wave duration is associated with paroxysmal lone atrial fibrillation. | Prolonged P-wave dispersion (PWD) and P-wave duration (PWdur) have been found to be associated with common atrial fibrillation (AF), but the association of P-wave indices with lone atrial fibrillation (LAF) is unclear.</AbstractText>We enrolled 61 paroxysmal LAF cases and 150 controls without AF. P-wave indices were me... |
12,521 | Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome. | Dravet syndrome is a severe form of intractable pediatric epilepsy with a high incidence of SUDEP: Sudden Unexpected Death in epilepsy. Cardiac arrhythmias are a proposed cause for some cases of SUDEP, yet the susceptibility and potential mechanism of arrhythmogenesis in Dravet syndrome remain unknown. The majority of ... |
12,522 | Insulinoma presenting with cardiac arrest and cardiomyopathy. | A 33-year-old woman presented with ventricular fibrillation cardiac arrest and was found to have a blood glucose of 1.83 mmol/L. Cardiac catheterisation revealed a dilated left ventricle with an ejection fraction (EF) of 26% and angiographically normal coronary arteries. Continuous dextrose infusion was required to tre... |
12,523 | Remote monitoring of a high-risk patient with Brugada syndrome: association of different arrhythmic manifestations. | We report on the remote arrhythmia monitoring of a 34-year-old man with highly symptomatic Brugada syndrome, who initially presented with syncope, paroxysmal atrial fibrillation, and spontaneous coved-type electrocardiogram. The patient received a dual-chamber implantable cardioverter-defibrillator (ICD) with Home Moni... |
12,524 | [The ICD in the terminal stage]. | ICDs are used to prevent sudden death caused by ventricular fibrillation. The number of patients with an ICD will keep growing. ICD shocks can severely disturb the dying process in terminally ill patients. Patients must be informed about this at the time of ICD implantation. The attending physician is responsible for p... |
12,525 | Differential clinical characteristics and prognosis of patients with longstanding persistent atrial fibrillation presenting with recurrent atrial tachycardia versus recurrent atrial fibrillation after first ablation. | It is unknown if baseline characteristics and prognosis of patients with longstanding persistent (defined as history greater than 1 year) atrial fibrillation (LS-AF) differ among those with either recurrent atrial tachycardia (R-AT) or recurrent AF (R-AF) after first ablation.</AbstractText>In 222 consecutive LS-AF pat... |
12,526 | Long-term outcomes of early surgery for asymptomatic severe chronic mitral regurgitation. | The long-term outcomes of early surgery in patients with asymptomatic severe chronic mitral regurgitation (MR) and the impact of preoperative left ventricular dysfunction, atrial fibrillation (AF) and/or pulmonary hypertension (PH) on outcomes in this patient group, were evaluated.</AbstractText>Between 1992 and 2007, ... |
12,527 | Global longitudinal strain in patients with suspected heart failure and a normal ejection fraction: does it improve diagnosis and risk stratification? | Many patients have clinical, structural or bio-marker evidence of heart failure (HF) but a normal left ventricular ejection fraction (LVEF; HeFNEF). Measurement of global longitudinal strain (GLS) may add diagnostic and prognostic information. Patients with symptoms suggesting heart failure and LVEF ≥50% were st... |
12,528 | Temporal variation and morphologic characteristics of J-waves in patients with early repolarisation syndrome. | Electrocardiographic markers identifying malignant forms of early repolarisation (ER) from ER of normal variants are of prime clinical importance. We compared the ECG parameters of ER patterns in patients with early repolarisation syndrome (ERS) proximate to the ventricular fibrillation (VF) episodes, remote from the e... |
12,529 | A de novo novel cardiac ryanodine mutation (Ser4155Tyr) associated with catecholaminergic polymorphic ventricular tachycardia. | We describe the case of a 14-year-old girl with a history of syncopal episodes triggered by stress or exercise. Catecholaminergic polymorphic ventricular tachycardia was diagnosed with the aid of an implantable loop recorder. The genetic testing of the patient and her family revealed a de novo novel missense mutation (... |
12,530 | Prolonged therapeutic hypothermia is more effective in attenuating brain apoptosis in a Swine cardiac arrest model. | To investigate whether 48 hours of therapeutic hypothermia is more effective to attenuate brain apoptosis than 24 hours and to determine whether the antiapoptotic effects of therapeutic hypothermia are associated with the suppressions of the cleavage of protein kinase C-δ, the cytosolic release of cytochrome c, a... |
12,531 | Diastolic function assessed from tagged MRI predicts heart failure and atrial fibrillation over an 8-year follow-up period: the multi-ethnic study of atherosclerosis. | The strain relaxation index (SRI), a novel diastolic functional parameter derived from tagged magnetic resonance imaging (MRI), is used to assess myocardial deformation during left ventricular relaxation. We investigated whether diastolic function indexed by SRI predicts heart failure (HF) and atrial fibrillation (AF) ... |
12,532 | Implantable intravascular defibrillator: defibrillation thresholds of an intravascular cardioverter-defibrillator compared with those of a conventional ICD in humans. | A percutaneous intravascular cardioverter-defibrillator (PICD) has been developed with a right ventricular (RV) single-coil lead and titanium electrodes in the superior vena cava (SVC)-brachiocephalic vein (BCV) region and the inferior vena cava (IVC).</AbstractText>To compare defibrillation thresholds (DFTs) of the PI... |
12,533 | TGF-β1 signal pathway in the regulation of inflammation in patients with atrial fibrillation. | To observe the expression changes of inflammatory markers TGF-β1, Smad3 and IL-6 in patients with atrial fibrillation (AF), and to explore the significance of TGF-β1 signaling pathway in the structural remodeling of AF.</AbstractText>The expression of TGF-β1, Smad3 and IL-6 in 50 cases with AF and 30 ... |
12,534 | Periatrial epicardial fat is associated with markers of endothelial dysfunction in patients with atrial fibrillation. | Epicardial adipose tissue (EAT) is associated to atrial fibrillation (AF) burden and outcome after AF ablation. We intended to determine whether global or local EAT is associated with systemic and/or left atrial (LA) inflammation and markers of endothelial dysfunction in AF patients.</AbstractText>Total, atrial, and ve... |
12,535 | Inequalities in heart failure in older men: prospective associations between socioeconomic measures and heart failure incidence in a 10-year follow-up study. | Socioeconomic position has been linked to incident heart failure (HF), but the underlying mechanisms are unclear. We examined the association of socioeconomic measures with incident HF in older adults and examined possible underlying pathways.</AbstractText>A socially representative cohort of men aged 60-79 years in 19... |
12,536 | Ulinastatin attenuates oxidation, inflammation and neural apoptosis in the cerebral cortex of adult rats with ventricular fibrillation after cardiopulmonary resuscitation. | The role of Ulinastatin in neuronal injury after cardiopulmonary resuscitation has not been elucidated. We aim to evaluate the effects of Ulinastatin on inflammation, oxidation, and neuronal injury in the cerebral cortex after cardiopulmonary resuscitation.</AbstractText>Ventricular fibrillation was induced in 76 adult... |
12,537 | Proteomics discovery of biomarkers for mitral regurgitation caused by mitral valve prolapse. | Mitral regurgitation (MR) is a common valvular lesion frequently caused by mitral valve prolapse (MVP). Surgical intervention in MVP patients with significant MR is predicated on symptoms and measures of left ventricular dysfunction. Because these indicators may be subjective or imprecise, serological biomarkers of dis... |
12,538 | Characterization of predictors of in-hospital cardiac complications of takotsubo cardiomyopathy: multi-center registry from Tokyo CCU Network. | Takotsubo cardiomyopathy (TC) is an acute cardiac syndrome characterized by transient left ventricular dysfunction and relatively good prognosis after discharge. However, cardiac complications during hospitalization remain to be fully determined. We attempted to determine features characterizing patients with adverse c... |
12,539 | Polymorphic ventricular tachycardia-part I: structural heart disease and acquired causes. | Polymorphic ventricular tachycardia (PMVT) is an unusual ventricular tachyarrhythmia. Perhaps its most unique characteristic is a continuously evolving QRS morphology. Although the most common substrate for PMVT is structural heart disease, the prevalence of sudden cardiac death in the population without structural hea... |
12,540 | Left atrial volumes and associated stroke subtypes. | Cardio embolism and cerebrovascular atherosclerosis are two major mechanisms of stroke. Studies investigating associations between advanced echocardiographic parameters and stroke mechanisms are limited.</AbstractText>This study is a standardized review of 633 patients admitted to the stroke service of a tertiary care ... |
12,541 | Mastocytosis presenting as cardiac emergency. | Mastocytosis is characterised by clonal proliferation of mast cells in the skin and in various internal organs, and by symptoms related to an acute release of mast cell-derived mediators. In 20-30 % of patients, mastocytosis occurs without the typical skin lesions of urticaria pigmentosa that are usually the first... |
12,542 | Calcium channel blockers improve exercise capacity and reduce N-terminal Pro-B-type natriuretic peptide levels compared with beta-blockers in patients with permanent atrial fibrillation. | Rate control of atrial fibrillation (AF) has become a main treatment modality, but we need more knowledge regarding the different drugs used for this purpose. In this study, we aimed to compare the effect of four common rate-reducing drugs on exercise capacity and levels of N-terminal pro-B-type natriuretic peptide (NT... |
12,543 | Transthoracic epicardial ablation of mitral isthmus for treatment of recurrent perimitral flutter. | Perimitral flutter (PMF) is a common form of left atrial tachycardia after atrial fibrillation (AF) ablation. The mitral isthmus (MI) is the standard ablation target. However, in some cases bidirectional block cannot be achieved.</AbstractText>The purpose of this study was to describe the first experience using a trans... |
12,544 | Propranolol prevents life-threatening arrhythmias in LQT3 transgenic mice: implications for the clinical management of LQT3 patients. | The efficacy of beta-blockers for treatment of patients with long QT syndrome type 3 (LQT3) has been repeatedly questioned, and it has been suggested that they might be detrimental for this genetic subgroup of patients with long QT syndrome (LQTS). The disquieting consequence has been that cardiologists confronted with... |
12,545 | Atrial fibrillation in heart failure: catheter and surgical interventional therapies. | Atrial fibrillation and heart failure commonly coexist in the same patient. Each may adversely affect the other. Atrial fibrillation leads to heart failure exacerbation, left ventricular function deterioration and an increase in thrombo-embolic risk. Therapeutic options targeting atrial fibrillation in heart failure pa... |
12,546 | Comparison of cold crystalloid and colloid infusions for induction of therapeutic hypothermia in a porcine model of cardiac arrest. | Large-volume cold intravenous infusion of crystalloids has been used for induction of therapeutic hypothermia after cardiac arrest. However, the effectiveness of cold colloids has not been evaluated. Therefore, we performed an experimental study to investigate the cooling effect of cold normal saline compared to colloi... |
12,547 | Long-term follow-up after autologous skeletal myoblast transplantation in ischaemic heart disease. | Short-term follow-up after autologous skeletal myoblasts (ASM) transplantation (Tx) (Myoblast Autologous Grafting in Ischaemic Cardiomyopathy (MAGIC) Phase II Study) for the treatment of ischaemic cardiomyopathy revealed improved left ventricular (LV) remodelling. Our study reports the longest long-term worldwide follo... |
12,548 | [Comparison of different electrocardiographic techniques for the detection of arrhythmias in horses]. | The aim of the study was to extend the range of the electrocardiographic examination in horses, evaluating the practicability of special electrocardiographic techniques (exercise- and Holter-ECG) and comparing these with more common techniques (resting-ECG) in equine medicine.</AbstractText>Electrocardiographic examina... |
12,549 | Hypothermic liquid ventilation prevents early hemodynamic dysfunction and cardiovascular mortality after coronary artery occlusion complicated by cardiac arrest in rabbits. | Ultrafast and whole-body cooling can be induced by total liquid ventilation with temperature-controlled perfluorocarbons. Our goal was to determine whether this can afford maximal cardio- and neuroprotections through cooling rapidity when coronary occlusion is complicated by cardiac arrest.</AbstractText>Prospective, r... |
12,550 | Identifiability of subgroup causal effects in randomized experiments with nonignorable missing covariates. | Although randomized experiments are widely regarded as the gold standard for estimating causal effects, missing data of the pretreatment covariates makes it challenging to estimate the subgroup causal effects. When the missing data mechanism of the covariates is nonignorable, the parameters of interest are generally no... |
12,551 | Outcomes of defibrillator therapy in catecholaminergic polymorphic ventricular tachycardia. | Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome characterized by adrenergically induced ventricular arrhythmias in patients with structurally normal hearts. Initiating triggered arrhythmias, such as bidirectional ventricular tachycardia, often degenerate into reentrant a... |
12,552 | Candidate gene approach to identifying rare genetic variants associated with lone atrial fibrillation. | Rare variants in candidate atrial fibrillation (AF) genes have been associated with AF in small kindreds. The extent to which such polymorphisms contribute to AF is unknown.</AbstractText>The purpose of this study was to determine the spectrum and prevalence of rare amino acid coding (AAC) variants in candidate AF gene... |
12,553 | Every patient with atrial fibrillation has his (her) own optimal heart rate. | Heart rate control is an important part of atrial fibrillation (AF) treatment and the recommendation for the target rate has become lenient in the recent guideline. Since heart rhythm of AF patients is irregularly irregular with great rate variation, the number of effective ventricular contractions may be different wit... |
12,554 | Learning electrocardiogram on YouTube: how useful is it? | YouTube has become a useful resource for knowledge and is widely used by medical students as an e-learning source. The purpose of this study was to assess the videos relating electrocardiogram (ECG) on YouTube.</AbstractText>YouTube was searched on May 28, 2013 for the search terms "AF ecg" for atrial fibrillation, "AV... |
12,555 | Brain natriuretic peptide in acute ischemic stroke. | Elevated serum brain natriuretic peptide (BNP) levels are associated with cardioembolic stroke mainly because of atrial fibrillation (AF). However, the mechanisms of increased serum BNP levels are hitherto unclear. We aimed to identify the factors associated with increased BNP levels in patients with acute ischemic str... |
12,556 | Poor prognosis of rare sarcomeric gene variants in patients with dilated cardiomyopathy. | In dilated cardiomyopathy (DCM), the clinical and prognostic implications of rare variants in sarcomeric genes remain poorly understood. To address this question, we analyzed the outcome of rare sarcomeric gene variants in patients enrolled in our Familial Cardiomyopathy Registry.</AbstractText>DCM families harboring r... |
12,557 | Early repolarization syndrome: electrocardiographic signs and clinical implications. | Early repolarization syndrome (ERS) was previously considered as a benign variant, but it has recently emerged as a risk marker for idiopathic ventricular fibrillation (VF) and sudden death. As measured by electrocardiogram (ECG), early repolarization is characterized by an elevation of the J point and/or ST segment fr... |
12,558 | Atrial flutter or fibrillation is the most frequent and life-threatening arrhythmia in myotonic dystrophy. | Several arrhythmias were reported in myotonic dystrophy (MD).</AbstractText>To evaluate the prevalence of atrial fibrillation (AF) and atrial flutter (AFL) in MD and the clinical consequences.</AbstractText>One hundred sixty-one patients, mean age 41 ± 14 years, were referred for a type 1 MD. All patients were asy... |
12,559 | Increase in prominence of electrocardiographic J waves after a single dose of propofol in a patient with early ventricular repolarisation. | J waves appear on an electrocardiogram as an elevation of the J point in the terminal portion of the QRS complex. J waves are often benign, but may be associated with malignant ventricular arrhythmias. In some cases, such problems appear to have been precipitated by propofol infusions. We observed a sudden increase in ... |
12,560 | Arrhythmogenesis after acute myocardial necrosis with and without preceding ischemia in rats. | The relative role of acute myocardial ischemia and infarction in ventricular arrhythmogenesis is incompletely understood. We compared the arrhythmia pattern after ischemia/infarction to that observed after direct myocardial necrosis without preceding ischemia in rats.</AbstractText>Coagulation necrosis was induced in W... |
12,561 | Effect of defibrillation threshold testing-induced ventricular fibrillation on renal function. | The effect of defibrillation threshold (DFT) testing with induction of ventricular fibrillation (VF) on renal function is currently unknown. This study examined the acute effect of DFT testing on renal function in patients undergoing implantable cardioverter defibrillator (ICD) implantation.</AbstractText>We performed ... |
12,562 | Suppression of ventricular fibrillation by electrical modification of the Purkinje system in hypertrophic cardiomyopathy. | A 56-year-old man in hypertrophic cardiomyopathy had an electrical storm caused by ventricular fibrillation (VF). Mapping during the initiation of the VF triggered by a premature ventricular contraction (PVC1), with right bundle branch block (RBBB)-like morphology and superior axis, demonstrated a prominent Purkinje-mu... |
12,563 | Programming implantable cardioverter-defibrillators in patients with primary prevention indication to prolong time to first shock: results from the PROVIDE study. | Shock therapy delivery by implantable cardioverter-defibrillators (ICD) can be painful and may have adverse consequences. Reducing shock burden for patients with ICDs would be beneficial.</AbstractText>PROVIDE was a prospective, randomized study of primary prevention ICD patients. Patients in the experimental group rec... |
12,564 | Prevalence and risk factors for cardiac diseases in a hospital-based population of 3,434 horses (1994-2011). | Risk factors for cardiac diseases in horses have not been explored in a large population of animals.</AbstractText>To describe risk factors for various cardiac diseases in a hospital-based population of horses.</AbstractText>Files of 3,434 horses admitted at the Internal Medicine Department of the Liege Equine Teaching... |
12,565 | Predictive value of atrial high-rate episodes for arterial stiffness and endothelial dysfunction in dual-chamber pacemaker patients. | Various pacing studies have demonstrated an association between right ventricular pacing (RVp) and atrial fibrillation (AF), even after preserving atrioventricular (AV) synchrony. We aimed to assess the interaction between arterial stiffness, endothelial function and atrial high-rate episodes (AHRE) in patients with du... |
12,566 | Novel heuristic search for ventricular arrhythmia detection using normalized cut clustering. | Processing of the long-term ECG Holter recordings for accurate arrhythmia detection is a problem that has been addressed in several approaches. However, there is not an outright method for heartbeat classification able to handle problems such as the large amount of data and highly unbalanced classes. This work introduc... |
12,567 | Simulation study of complex action potential conduction in atrioventricular node. | The atrioventricular (AV) node, which is located between the atria and ventricles of the heart, acts as important roles in cardiac excitation conduction between the two chambers. Although there are multiple conduction pathways in the AV node, the structure of the AV node has not been clarified. In this study, we constr... |
12,568 | Blind source separation in characterizing ECG pre-shock waveforms during Ventricular Fibrillation. | Ventricular Fibrillation (VF) is a cardiac arrhythmia for which the only available treatment option is defibrillation by electrical shock. Existing literature indicates that VF could be the manifestation of different sources controlling the heart with different degrees of organization. In this work we test the hypothes... |
12,569 | Effect of premature activation in analyzing QT dynamics instability using QT-RR model for ventricular fibrillation and healthy subjects. | Perturbations in the normal heart rate are generally represented by the presence of premature activation (PA) beats in the surface electrocardiogram (ECG). The presence of PA is one of the main reasons of instability in QT dynamics which could initiate arrhythmia. Analyzing Boundary-Input Boundary-Output (BIBO) stabili... |
12,570 | Chaotic phase space differential algorithm for real-time detection of ventricular arrhythmias: application in animal model. | Life-threatening ventricular arrhythmias remain the main cause of death among patients with cardiovascular diseases. Efforts have been spent on early detection of such fatal cardiac signs. We have previously reported a novel chaotic phase space differential (CPSD) algorithm in discriminating VPC, VT, and VF from normal... |
12,571 | Models of ventricular arrhythmia mechanisms. | The mechanisms that initiate and sustain ventricular arrhythmias in the human heart are clinically important, but hard to study experimentally. In this study, a monodomain model of electrical activation was used to examine how dynamics of electrophysiology at the cell scale influence the surface activation patterns of ... |
12,572 | Automated signal pattern detection in ECG during human ventricular arrhythmias. | Ventricular arrhythmias seriously affects cardiac function. Of these arrhythmias, Ventricular fibrillation is considered as a lethal cardiac condition. Recent studies have reported that ventricular arrhythmias are not completely random and may exhibit regional spatio-temporal organizations. These organizations could be... |
12,573 | Cardiac resynchronization therapy in acute pulmonary edema: A case report. | We are reporting a case of 71-year old lady with a dual chamber demand pacemaker, who developed acute pulmonary edema due to an acute left ventricular (LV) dysfunction and worsening in mitral valve regurgitation after atrioventricular nodal ablation for uncontrolled atrial fibrillation. This was attributed to right ven... |
12,574 | Subcutaneous implantable defibrillator: State-of-the art 2013. | The subcutaneous implantable cardioverter-defibrillator (S-ICD) has recently been approved for commercial use in Europe, New Zealand and the United States. It is comprised of a pulse generator, placed subcutaneously in a left lateral position, and a parasternal subcutaneous lead-electrode with two sensing electrodes se... |
12,575 | Hyperacute drug-induced hepatitis with intravenous amiodarone: case report and review of the literature. | Amiodarone is a benzofuran class III antiarrhythmic drug used to treat a wide spectrum of ventricular tachyarrhythmias. The parenteral formulation is prepared in polysorbate 80 diluent. We report an unusual case of acute elevation of aminotransaminase concentrations after the initiation of intravenous amiodarone. An 88... |
12,576 | Safety and efficacy of strategic implantable cardioverter-defibrillator programming to reduce the shock delivery burden in a primary prevention patient population. | Strategically chosen ventricular tachycardia (VT)/ventricular fibrillation (VF) detection and therapy parameters aimed at reducing shock deliveries were proven effective in studies that utilized single manufacturer devices with a follow-up of up to 1 year. Whether these beneficiary effects can be generalized to additio... |
12,577 | Pulmonary vein isolation in patients with Brugada syndrome and atrial fibrillation: a 2-year follow-up. | Pharmacological treatment of atrial fibrillation (AF) in the setting of Brugada syndrome (BS) might be challenging as many antiarrhythmic drugs (AADs) with sodium channel blocking properties might expose the patients to the development of ventricular arrhythmias. Moreover, patients with BS and implantable cardioverter-... |
12,578 | An observational study of extracorporeal CPR for in-hospital cardiac arrest secondary to myocardial infarction. | To determine the effects of extracorporeal cardiopulmonary resuscitation (ECPR) in patients with in-hospital cardiac arrest (IHCA) due to acute myocardial infarction (AMI).</AbstractText>IHCA patients due to AMI undergoing CPR between 1 January 2006 and 1 July 2010 were analysed retrospectively. We compared the surviva... |
12,579 | Gender-related safety and efficacy of cardiac resynchronization therapy. | Cardiac resynchronization therapy (CRT) is an established therapy for patients with chronic heart failure (CHF) and a broad QRS complex. Gender-related safety and efficacy data are necessary for informed patient decision-making for female patients with CHF. The aim of the study was to assess the effects of gender on th... |
12,580 | Heart failure in patients with atrial fibrillation is associated with a high symptom and hospitalization burden: the RealiseAF survey. | Atrial fibrillation (AF) and heart failure (HF) often coexist; the consequences of such coexistence are unclear.</AbstractText>HF in patients with AF is associated with poor outcomes.</AbstractText>This post hoc analysis of RealiseAF, a survey of AF patients, compared symptoms, hospitalizations, management, and AF cont... |
12,581 | [Monomorphic ventricular tachycardia during the ajmaline test]. | A 44-year-old male patient admitted with palpitations was diagnosed with tachycardia with wide QRS, but recovered after being treated with amiodarone. The patient's coronary angiography was normal. As the patient's resting ECG was compatible with Brugada type 2, an ajmaline challenge test was scheduled. The infusion pr... |
12,582 | Perioperative conduction disturbances after transcatheter aortic valve replacement. | Cardiac conduction disturbances after transcatheter aortic valve replacement (TAVR) are common and important. The risk factors and outcome effects of atrial fibrillation after TAVR recently have been appreciated. The paucity of clinical trials has resulted in the absence of clinical guidelines for the management of thi... |
12,583 | Intra-cardiac thrombus resolution after anti-coagulation therapy with dabigatran in a patient with mid-ventricular obstructive hypertrophic cardiomyopathy: a case report. | Although dabigatran, a novel oral anti-coagulant, has been approved for the prevention of thromboembolism in patients with non-valvular atrial fibrillation, the efficacy of dabigatran for the resolution of established intra-cardiac thrombi has not been validated. Herein is describe a case in which dabigatran was effect... |
12,584 | Does health-related quality of life predict hospitalization or mortality in patients with atrial fibrillation? | Poor health-related quality of life (QOL) is related to morbidity and mortality in coronary heart disease and ventricular arrhythmias as well as to mortality in patients with heart failure (HF) and atrial fibrillation (AF). This study examined the contributions of QOL to the prediction of 1-year hospitalization and mor... |
12,585 | Endocavitary structures in the outflow tract: anatomy and electrophysiology of the conus papillary muscles. | Catheter ablation is an increasingly used and successful treatment choice for right ventricular outflow tract (RVOT) arrhythmias. While the role of endocavitary structures and the regional morphology of the ventricular inflow tract and the right atrium as a cause for difficulty with successful ablation are well describ... |
12,586 | Low-tilt monophasic and biphasic waveforms compared with standard biphasic waveforms in the transvenous defibrillation of ventricular fibrillation. | Commercially available implantable defibrillators utilize a high-tilt waveform. Studies in atrial fibrillation and transthoracic defibrillation of ventricular fibrillation (VF) have shown improved defibrillation efficacy using low-tilt (LT) waveforms. We investigated the feasibility, efficacy, and safety of a LT wavefo... |
12,587 | Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial fibrillation. | Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with an increased risk for stroke, heart failure and cardiovascular-related mortality. Candidate targets for anti-AF drugs include a potassium channel K(v)1.5, and the ionic currents I(KACh) and late I(Na), along with increased oxidative s... |
12,588 | Treating resistant hypertension: role of renal denervation. | Arterial hypertension is the most prevalent risk factor associated with increased cardiovascular morbidity and mortality. Although pharmacological treatment is generally well tolerated, 5%-20% of patients with hypertension are resistant to medical therapy, which is defined as blood pressure above goal (>140/90 mmHg ... |
12,589 | Prevalence of atrial fibrillation in China and its risk factors. | To study the prevalence of atrial fibrillation (AF) and the relation with its risk factors in China.</AbstractText>A total of 19 363 participants (8635 males and 10 728 females) aged ⋝35 years in geographically dispersed urban and rural regions of China were included in this cross-sectional survey. All participa... |
12,590 | Epicardial adipose tissue is associated with prevalent atrial fibrillation in patients with hypertrophic cardiomyopathy. | Prevalent atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM) represents an important issue with regard to stroke events caused by embolization and is associated with high mortality. Increased epicardial adipose tissue (EAT), which shows high metabolic activity, can locally influence the activit... |
12,591 | Role of electrical storm as a mortality and morbidity risk factor and its clinical predictors: a meta-analysis. | Electrical storm (ES) is a devastating and life-threatening event in clinical practice, but its real weight as a risk factor and its clinical predictors remain unclear. Our objective was to evaluate ES as a mortality and morbidity risk factor and to define the clinical variables associated with ES.</AbstractText>The me... |
12,592 | A novel KCNQ1 missense mutation identified in a patient with juvenile-onset atrial fibrillation causes constitutively open IKs channels. | Atrial fibrillation (AF) is one of the most common cardiac arrhythmias. In some patients, the disease is inheritable; however, hereditary aspects of AF remain not fully elucidated.</AbstractText>The purpose of this study was to identify genetic backgrounds that contribute to juvenile-onset AF and to define the mechanis... |
12,593 | The role of the autonomic nervous system in cardiac arrhythmias. | Autonomic nervous system activity exerts potent and diverse effects on cardiac rhythm through elaborate neurocircuitry that is integrated at multiple levels. Adrenergic activity such as is associated with mental or physical stress or as a reflex response to myocardial ischemia is capable of generating significant rhyth... |
12,594 | Transmembrane current imaging in the heart during pacing and fibrillation. | Recently, we described a method to quantify the time course of total transmembrane current (Im) and the relative role of its two components, a capacitive current (Ic) and a resistive current (Iion), corresponding to the cardiac action potential during stable propagation. That approach involved recording high-fidelity (... |
12,595 | Screening of MYH7, MYBPC3, and TNNT2 genes in Brazilian patients with hypertrophic cardiomyopathy. | Hypertrophic cardiomyopathy (HC) is the most prevalent genetic cardiac disease caused by a mutation in sarcomeres, Z-disks, or calcium-handling genes and is characterized by unexplained left ventricular hypertrophy. The aim of this study was to determine the genetic profile of Brazilian patients with HC and correlate t... |
12,596 | Atrial natriuretic Peptide single nucleotide polymorphisms in patients with nonfamilial structural atrial fibrillation. | Atrial natriuretic peptide (ANP) has antihypertrophic and antifibrotic properties that are relevant to AF substrates. The -G664C and rs5065 ANP single nucleotide polymorphisms (SNP) have been described in association with clinical phenotypes, including hypertension and left ventricular hypertrophy. A recent study asses... |
12,597 | Morbidity and mortality in a large series of surgical patients with pulmonary metastases of colorectal carcinoma: a prospective multicentre Spanish study (GECMP-CCR-SEPAR). | Little information is available on postoperative morbidity and mortality after pulmonary metastasectomy. We describe the postoperative morbidity and mortality in a large multicentre series of patients after a first surgical procedure for pulmonary metastases of colorectal carcinoma (CRC) and identify the pre- and intra... |
12,598 | Low efficacy of cardioversion of persistent atrial fibrillation with the implantable cardioverter-defibrillator. | Atrial fibrillation (AF) and heart failure are conditions that often coexist. Consequently, many patients with an implantable cardioverter-defibrillator (ICD) present with AF. We evaluated the effectiveness of internal cardioversion of AF in patients with an ICD.</AbstractText>Retrospectively, we included 27 consecutiv... |
12,599 | Resuscitation with lipid, epinephrine, or both in levobupivacaine-induced cardiac toxicity in newborn piglets. | The optimal dosing regimens of lipid emulsion, epinephrine, or both are not yet determined in neonates in cases of local anaesthetic systemic toxicity (LAST).</AbstractText>Newborn piglets received levobupivacaine until cardiovascular collapse occurred. Standard cardiopulmonary resuscitation was started and electrocard... |
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