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13,500 | Glucagon-like peptide-1 preserves coronary microvascular endothelial function after cardiac arrest and resuscitation: potential antioxidant effects. | Glucagon-like peptide-1 (GLP-1) has protective effects in the heart. We hypothesized that GLP-1 would mitigate coronary microvascular and left ventricular (LV) dysfunction if administered after cardiac arrest and resuscitation (CAR). Eighteen swine were subjected to ventricular fibrillation followed by resuscitation. S... |
13,501 | Ventricular fibrillation conduction through an isthmus of preserved myocardium between radiofrequency lesions. | Selective local acceleration of myocardial activation during ventricular fibrillation (VF) contributes information on the interactions between neighboring zones during the arrhythmia. This study analyzes these interactions, centering the observations on an isthmus of myocardium between two radiofrequency (RF) lesions.<... |
13,502 | Use of a noninvasive continuous monitoring device in the management of atrial fibrillation: a pilot study. | Outpatient ambulatory cardiac rhythm monitoring is a routine part of the management of patients with paroxysmal atrial fibrillation (AF). Current systems are limited by patient convenience and practicality.</AbstractText>We compared the Zio(®) Patch, a single-use, noninvasive waterproof long-term continuous monito... |
13,503 | Impact of Atrial Fibrillation On Cardiovascular Mortality in the Setting of Myocardial Infarction. | Atrial fibrillation (AF) commonly occurs in patient with acute myocardial infarction (AMI). Potential triggers for AF development in this setting includes reduced left ventricular function, advanced diastolic dysfunction and mitral regurgitation leading to elevated left atrial pressures and atrial stretch. Other trigge... |
13,504 | Omega-3 Polyunsaturated Fatty Acid Supplementation: Mechanism and Current Evidence in Atrial Fibrillation. | Atrial fibrillation (AF) is the most prevalent arrhythmia and is associated with considerable morbidity and mortality. Available pharmacologic antiarrhythmic therapies are often ineffective in preventing the recurrence of AF, possibly because these drugs target a single pathophysiological mechanism. Given their benefic... |
13,505 | Role of Left Ventricular Diastolic Dysfunction in Predicting Atrial Fibrillation Recurrence after Successful Electrical Cardioversion. | The role of left ventricular (LV) diastolic dysfunction in predicting atrial fibrillation (AF) recurrence after successful electrical cardioversion is largely unknown. Studies suggest that there may be a link between abnormal LV compliance and the initial development, and recurrence of AF after electrical cardioversion... |
13,506 | Reversal of Dilated Cardiomyopathy After Successful Radio-Frequency Ablation of Frequent Atrial Premature Beats, a New Cause for Arrhythmia-Induced Cardiomyopathy. | Incessant atrial premature beats as a potential cause for tachycardia-induced cardiomyopathy was suspected in a patient presenting with dilated non-ischemic cardiomyopathy and severely altered left ventricular ejection fraction. The elimination of a left atrial focus by percutaneous RF ablation led to normalization of ... |
13,507 | Positive QRS complex in lead i as a malignant sign in right ventricular outflow tract tachycardia: comparison between polymorphic and monomorphic ventricular tachycardia. | Idiopathic ventricular fibrillation (VF) or polymorphic ventricular tachycardia (PVT) arising from the right ventricular outflow tract (RVOT) is occasionally observed. The difference in the initial ventricular premature contraction (VPC) between VF/PVT and monomorphic VT (MVT) from the RVOT, however, has not yet been f... |
13,508 | [Irbesartan in clinical practice]. | Irbesartan is a noncompetitive angiotensin II receptor type 1 antagonist which has been successfully used for more than 10 years for the treatment of hypertensive disease. In a dose of 150-300 mg/day irbesartan produces long term effect for 24 hours. Its antihypertensive efficacy is augmented by concomitant administrat... |
13,509 | [Noncompaction myocardium as a primary phenomenon or consequence of myocardial dysfunction: clinical masks of the syndrome]. | Noncompaction myocardium (NCM) is a genetic heterogeneous primary cardiomyopathy which affects both children and adults and can be either isolated or combined with other congenital heart disorders. It has common pathogenesis of symptoms but is distinguished by pronounced clinical polymorphism. We have observed 25 adult... |
13,510 | Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction. | Atrio-ventricular conduction disease is a common feature in Mendelian rhythm disorders associated with sudden cardiac death and is characterized by prolongation of the PR interval on the surface electrocardiogram (ECG). Prolongation of the PR interval is also a strong predictor of atrial fibrillation, the most prevalen... |
13,511 | Ventricular arrhythmias in patients with implanted ventricular assist devices: a contemporary review. | Ventricular arrhythmia (VA) is a significant factor in the clinical management of patients with congestive heart failure (CHF). Understanding the implications of VA in ventricular assist device-supported CHF patients is critical to appropriate clinical decision making in this special population. This article details re... |
13,512 | Intra-aortic balloon pump (ΙΑΒΡ): from the old trends and studies to the current "extended" indications of its use. | This report outlines the well defined indications of using IABP and also favours extending the indications of IABP use, to include not only "therapeutically" the aging unstable patients but also "prophylactically" patients with low EF or high Euroscore. |
13,513 | Chest compression-only cardiopulmonary resuscitation for out-of-hospital cardiac arrest with public-access defibrillation: a nationwide cohort study. | It remains unclear which is more effective to increase survival after out-of-hospital cardiac arrest in those with public-access defibrillation, bystander-initiated chest compression-only cardiopulmonary resuscitation (CPR) or conventional CPR with rescue breathing.</AbstractText>A nationwide, prospective, population-b... |
13,514 | Ability to induce atrial fibrillation in the peri-operative period is associated with phosphorylation-dependent inhibition of TWIK protein-related acid-sensitive potassium channel 1 (TASK-1). | Peri-operative atrial fibrillation (peri-op AF) is a common complication following thoracic surgery. This arrhythmia is thought to be triggered by an inflammatory response and can be reproduced in various animal models. Previous work has shown that the lipid inflammatory mediator, platelet-activating factor (PAF), synt... |
13,515 | Ventricular activity morphological characterization: ectopic beats removal in long term atrial fibrillation recordings. | Ectopic beats are early heart beats remarkably different to the normal beat morphology that provoke serious disturbances in electrocardiographic analysis. These beats are very common in atrial fibrillation (AF), causing important residua when ventricular activity has to be removed for atrial activity (AA) analysis. In ... |
13,516 | Radial basis function neural networks applied to efficient QRST cancellation in atrial fibrillation. | The most extended noninvasive technique for medical diagnosis and analysis of atrial fibrillation (AF) relies on the surface elctrocardiogram (ECG). In order to take optimal profit of the ECG in the study of AF, it is mandatory to separate the atrial activity (AA) from other cardioelectric signals. Traditionally, templ... |
13,517 | Early repolarization with horizontal ST segment may be associated with aborted sudden cardiac arrest: a retrospective case control study. | Risk stratification of the early repolarization pattern (ERP) is needed to identify malignant early repolarization. J-point elevation with a horizontal ST segment was recently suggested as a malignant feature of the ERP. In this study, the prevalence of the ERP with a horizontal ST segment was examined among survivors ... |
13,518 | The changing pattern of endomyocardial fibrosis in South-west Nigeria. | Endomyocardial fibrosis (EMF) is a restrictive cardiomyopathy, the prevalence of which is declining globally. This study was carried out to determine if there were changing patterns in its local prevalence in South-West Nigeria.</AbstractText>We reviewed the medical records of all patients admitted to or attending the ... |
13,519 | Insights from cardiac development relevant to congenital defects and adult clinical anatomy. | Advances made in understanding temporal changes in structure of the developing heart, along with advances in knowledge of the lineage of cardiomyocytes forming the components of cardiac chambers, permit us to draw inferences concerning substrates for arrhythmias such as atrial fibrillation and outflow tract tachycardia... |
13,520 | Shock or no shock - a question of philosophy or should intraoperative implantable cardioverter defibrillator testing be recommended? | Implantation of implantable cardioverter defibrillators (ICDs) in patients with a high risk for life-threatening ventricular arrhythmias is a standard therapy. The development of new ICD leads, shock algorithms, high-energy defibrillators and rapid energy supply has improved the devices. Nevertheless, the discussion re... |
13,521 | Effect of bucindolol on heart failure outcomes and heart rate response in patients with reduced ejection fraction heart failure and atrial fibrillation. | There is little evidence of beta-blocker treatment benefit in patients with heart failure and reduced left ventricular ejection fraction (HFREF) and atrial fibrillation (AF). We investigated the effects of bucindolol in HFREF patients with AF enrolled in the Beta-blocker Evaluation of Survival Trial (BEST).</AbstractTe... |
13,522 | Dissimilar ventricular rhythms: implications for ICD therapy. | Sensing of left ventricular (LV) activity in some devices used for cardiac resynchronization therapy (CRT) was designed primarily to prevent the delivery of an LV stimulus into the LV vulnerable period. Such a sensing function of the LV channel is not universally available in contemporary CRT devices. Recordings of LV ... |
13,523 | Antipsychotic drugs are associated with pulseless electrical activity: the Oregon Sudden Unexpected Death Study. | There has been a paradigm shift in the manifestation of sudden cardiac arrest (SCA), with steadily decreasing rates of ventricular fibrillation/tachycardia (VF/VT) and a significant increase in the proportion of pulseless electrical activity (PEA) and asystole.</AbstractText>Since PEA is marked by failure of myocardial... |
13,524 | Mechanisms of ranolazine's dual protection against atrial and ventricular fibrillation. | Coronary artery disease and heart failure carry concurrent risk for atrial fibrillation and life-threatening ventricular arrhythmias. We review evidence indicating that at therapeutic concentrations, ranolazine has potential for dual suppression of these arrhythmias. Mechanisms and clinical implications are discussed. |
13,525 | Change of B-type natriuretic peptide after surgery and its association with rhythm status in patients with chronic severe mitral regurgitation. | B-type natriuretic peptide (BNP) is a useful biomarker of cardiac function in patients with mitral regurgitation (MR). However, the change in BNP in association with rhythm status after corrective surgery has not been studied.</AbstractText>A total of 101 patients with chronic severe MR undergoing surgery were prospect... |
13,526 | [Arrhythmogenic right ventricular cardiomyopathy as a cause of sudden death in young people--literature review]. | Arrhythmogenic right ventricular cardiomyopathy/dysplasia is a progressive condition with right ventricular myocardium being replaced by fibro-fatty tissue. It is a hereditary disorder mostly caused by desmosome gene mutations. The prevalence of arrhythmogenic right ventricular cardiomyopathy is about 1/1000-5000. Clin... |
13,527 | Restored left ventricular function following transcatheter closure of a persistent ductus arteriosus in an adult. | Recently, transcatheter device occlusion has become the first choice treatment for adult persistent ductus arteriosus (PDA). However, various complications such as atrial fibrillation requiring anticoagulation, pulmonary hypertension, and ventricular dysfunction may challenge the interventionist. We report a 61-year-ol... |
13,528 | [Ultrasound in the electrophysiological cardiac catheterization laboratory]. | During recent years the need for intraprocedural imaging has increased. Fluoroscopy and angiography are frequently supplemented by pre-procedural magnetic resonance or computed tomography imaging as well as electroanatomic mapping techniques. However, poor real-time imaging quality of soft tissue, radiation exposure, a... |
13,529 | Effect of age on treatment, trends and outcome of patients hospitalized with atrial fibrillation: insights from a 20-years registry in a Middle-Eastern country (1991-2010). | Most studies on atrial fibrillation (AF) epidemiology, treatment, and outcomes have included mainly Caucasians patients. The world literature on AF in other ethnicities is very limited particularly in the elderly.</AbstractText>The aim of this study was to compare the clinical characteristics, treatment and outcome of ... |
13,530 | Cause of very late recurrence of atrial fibrillation or flutter after catheter ablation for atrial fibrillation. | The major mechanism underlying the early recurrence of atrial fibrillation (AF) after ablation is mainly reconnection of the isolated pulmonary vein (PV); however, the mechanism responsible for very late recurrence (VLR) has not been fully elucidated. The purpose of the present study was to investigate the mechanism un... |
13,531 | Telemedicine and cardiac implants: what is the benefit? | Cardiac implantable electronic devices are increasing in prevalence. The post-implant follow-up is important for monitoring both device function and patient condition. However, practice is inconsistent. For example, ICD follow-up schedules vary from 3 monthly to yearly according to facility and physician preference and... |
13,532 | Role of defibrillation threshold testing in the contemporary defibrillator patient population. | Defibrillation threshold (DFT) testing has been performed to prove functionality of the implantable cardioverter defibrillator (ICD). Over the past years it has become increasingly controversial because of possible morbidity and mortality. The goal of this study was to determine unsuccessful shock testing and report st... |
13,533 | Comparison of fixed tilt and tuned defibrillation waveforms: the PROMISE study. | All modern defibrillation systems use biphasic shock waveforms. Typically a fixed tilt waveform is used for implantable defibrillators (ICDs), but a tuned waveform with duration based on shock impedance may be superior based on theoretical calculations.</AbstractText>The objective of this study was to compare defibrill... |
13,534 | Kounis-Zavras syndrome presenting with ventricular arrhythmias and cardiogenic shock. | In this case report we describe a case of the Kounis-Zavras syndrome (coincidental occurrence of chest pain and allergic reactions accompanied by clinical and laboratory findings of cardiac ischemia). A 34-year-old woman presented to the emergency unit with severe chest pain from 2 h. She reported a medical histor... |
13,535 | New insights into the beneficial electrophysiologic profile of ranolazine in heart failure: prevention of ventricular fibrillation with increased postrepolarization refractoriness and without drug-induced proarrhythmia. | Ranolazine inhibits late Na(+) and K(+) currents. Earlier studies have reported an antiarrhythmic effect. The aim of the present study was to understand whether ranolazine could still preserve its antiarrhythmic properties in the settings of chronic heart failure (CHF).</AbstractText>In 12 female rabbits, CHF was induc... |
13,536 | Successful coronary angiography with adequate image acquisition using a combination of gadolinium and a power injector in a patient with severe iodine contrast allergy. | A history of severe allergic reaction to iodine contrast leading to anaphylactic shock presents a dilemma in patients requiring cardiac catheterization. As an alternative, gadolinium has been an interesting and potentially useful agent. However, gadolinium produces poor image quality and has been associated with signif... |
13,537 | Assessment of genetic causes of cardiac arrest. | Unexplained cardiac arrest is defined as a cardiac arrest in the absence of coronary artery disease and overt structural heart disease, present in 5%-10% of cardiac arrest survivors. A genetic contribution to cardiac arrest is more common in this population, most commonly attributed to an inherited ion channel abnormal... |
13,538 | Detection of subclinical atrial dysfunction by two-dimensional echocardiography in patients with overt hyperthyroidism. | Hyperthyroidism is an important cardiovascular risk factor in the development of atrial fibrillation and heart failure. Increased atrial electromechanical intervals are used to predict atrial fibrillation, measured by tissue Doppler imaging (TDI).</AbstractText>To evaluate atrial electromechanical delay (EMD) and left ... |
13,539 | Alternative approach to improving survival of patients with out-of-hospital primary cardiac arrest. | Out-of-hospital cardiac arrest (OHCA) is a common cause of death. In spite of recurring updates of guidelines, the survival of patients with OHCA was essentially unchanged from the mid 1970s to the mid 2000s, averaging 7.6% for all OHCA and 17.7% for OHCA due to ventricular fibrillation. In the past, changes in one's a... |
13,540 | Midlife stroke risk and cognitive decline: a 10-year follow-up of the Whitehall II cohort study. | Stroke is associated with an increased risk of dementia. However, it is unclear whether risk of stroke in those free of stroke, particularly in nonelderly populations, leads to differential rates of cognitive decline. Our aim was to assess whether risk of stroke in mid life is associated with cognitive decline over 10 ... |
13,541 | [Research on automatic external defibrillator based on DSP]. | Electrical defibrillation is the most effective way to treat the ventricular tachycardia (VT) and ventricular fibrillation (VF). An automatic external defibrillator based on DSP is introduced in this paper. The whole design consists of the signal collection module, the microprocessor controlingl module, the display mod... |
13,542 | High E/e' disrupts the rapid lowering of blood glucose in response to exercise training. | No relationship between the ratio of peak early velocity of left ventricular inflow to peak systolic longitudinal velocity of the mitral annulus velocity (E/e') and insulin resistance has yet been shown in patients with cardiac disease. We hypothesized that patients with high E/e' values would tend not to show the rapi... |
13,543 | Anxiety and risk of ventricular arrhythmias or mortality in patients with an implantable cardioverter defibrillator. | A subgroup of patients with an implantable cardioverter defibrillator (ICD) experiences anxiety after device implantation. The purpose of the present study was to evaluate whether anxiety is predictive of ventricular arrhythmias and all-cause mortality 1 year post ICD implantation.</AbstractText>A total of 1012 patient... |
13,544 | Omega-3 fatty acids and cardiac arrhythmias. | There are suggestions of effects of marine omega-3 polyunsaturated fatty acids (PUFAs) in relation to ventricular arrhythmia and sudden cardiac death and, more recently, also of possible effects related to atrial fibrillation.</AbstractText>On the basis of the recently published human studies, this article not only foc... |
13,545 | The importance of increased percentage of biventricular pacing to improve clinical outcomes in patients receiving cardiac resynchronization therapy. | To describe the growing evidence that a maximal biventricular pacing is needed to gain the maximal benefits from cardiac resynchronization therapy (CRT).</AbstractText>Even small gains in the biventricular (BIV) pacing percentage are clinically important both to prevent acute heart failure and, more importantly, to imp... |
13,546 | Epinephrine for cardiac arrest. | Epinephrine is the primary drug administered during cardiopulmonary resuscitation (CPR) to reverse cardiac arrest. Epinephrine increases arterial blood pressure and coronary perfusion during CPR via alpha-1-adrenoceptor agonist effects. However, the dose, timing and indications for epinephrine use are based on limited ... |
13,547 | Left ventricular diastolic function is closely associated with mechanical function of the left atrium in patients with paroxysmal atrial fibrillation. | Left ventricular (LV) diastolic dysfunction may be a mechanism of left atrial (LA) electroanatomical remodeling in atrial fibrillation (AF). We evaluated the association between LV diastolic function and LA mechanical function in non-valvular paroxysmal AF (PAF).</AbstractText>In 286 patients with PAF (males 73%, 57 &#... |
13,548 | Pilot randomized trial of outpatient cardiac monitoring after cryptogenic stroke. | Observational studies indicate that outpatient cardiac monitoring detects previously undiagnosed atrial fibrillation (AF) in 5% to 20% of patients with recent stroke. However, it remains unknown whether the yield of monitoring exceeds that of routine clinical follow-up.</AbstractText>In a pilot trial, we randomly assig... |
13,549 | QTc prolongation prior to angiography predicts poor outcome and associates significantly with lower left ventricular ejection fractions and higher left ventricular end-diastolic pressures. | QT prolongation on the surface ECG is associated with sudden cardiac death. The cause of QT prolongation in ischaemic heart disease (IHD) patients remains unknown, but may be due to a complex interplay between genetic factors and impaired systolic and/or diastolic function through as yet unexplained mechanisms. It was ... |
13,550 | Diastolic dysfunction of aging is independent of myocardial structure but associated with plasma advanced glycation end-product levels. | Heart failure is associated with abnormalities of myocardial structure, and plasma levels of the advanced glycation end-product (AGE) N(ε)-(carboxymethyl)lysine (CML) correlate with the severity and prognosis of heart failure. Aging is associated with diastolic dysfunction and increased risk of heart failure, and... |
13,551 | Comparison of the intrinsic vasorelaxant and inotropic effects of the antiarrhythmic agents vernakalant and flecainide in human isolated vascular and cardiac tissues. | This study explored the intrinsic vasorelaxant and inotropic effects of the mixed potassium and sodium channel blocker atrial antiarrhythmic vernakalant and the class IC antiarrhythmic agent flecainide in human isolated subcutaneous resistance artery and in ventricular trabecular muscle preparations. At test concentrat... |
13,552 | The prevalence of early repolarization variant in Turkish male subjects: a clinical single center study. | Early repolarization variant (ERV) detected in surface ECG has traditionally been considered a benign finding, but the presence of this pattern has recently been associated with vulnerability to ventricular fibrillation in many case reports and case-control studies. There is no information regarding the prevalence of E... |
13,553 | Left atrial mechanical function and stiffness in patients with paroxysmal atrial fibrillation. | Abnormalities in the left atrial (LA) structure and function may develop in patients with paroxysmal atrial fibrillation (AF). We sought to determine the contribution of LA mechanical function, including LA stiffness, to AF by comparing patients with paroxysmal AF with normal control subjects, and to evaluate whether L... |
13,554 | Incidence and predictors of phantom shocks in implantable cardioverter defibrillator recipients. | Implantable cardioverter defibrillators (ICDs) are designed to deliver shocks or antitachycardia pacing (ATP) in the event of ventricular arrhythmias. During follow-up, some ICD recipients experience the sensation of ICD discharge in the absence of an actual discharge (phantom shock). The aim of this study was to evalu... |
13,555 | Atrial giant cell myocarditis: a distinctive clinicopathologic entity. | Giant cell myocarditis (GCM) typically causes fulminant heart failure, arrhythmias, or heart block, necessitating aggressive immunosuppression, ventricular assist device insertion, or cardiac transplantation. We describe a novel variant of GCM, primarily involving the atria, that displays distinctive clinical features ... |
13,556 | [QT prolongation and ventricular fibrillation caused by acute necrotising pancreatitis in a young female patient]. | Electrocardiographic alterations associated with acute pancreatitis (AP) have been known for decades. This association may be of particular importance in differential diagnosis, since authors have reported ECG abnormalities suggestive of myocardial infarction. The pathophysiological mechanism of these ECG changes has r... |
13,557 | Contribution of out-of-hospital factors to a reduction in cardiac arrest mortality after witnessed ventricular fibrillation or tachycardia. | Mortality rates in Osaka for cardiac arrest after witnessed ventricular tachycardia (VT) or ventricular fibrillation (VF) have decreased dramatically. We sought to estimate the contribution of changes in out-of-hospital care to this decrease.</AbstractText>We applied a previously validated statistical model, IMPACT, to... |
13,558 | Rescue pulmonary vein isolation for hemodynamically unstable atrial fibrillation storm in a patient with an acute extensive myocardial infarction. | New-onset atrial fibrillation in patients hospitalized for an acute myocardial infarction often leads to hemodynamic deterioration and has serious adverse prognostic implications; mortality is particularly high in patients with congestive heart failure and/or a reduced left ventricular ejection fraction. The mechanism ... |
13,559 | Regional and transmural dispersion of repolarisation in patients with Emery-Dreifuss muscular dystrophy. | The development of malignant ventricular arrhythmias is a possible feature in Emery-Dreifuss muscular dystrophy (EDMD) patients with normal left ventricular systolic function. This event may be the cause of sudden cardiac death in EDMD patients. QTc dispersion (QTc-D), JTc dispersion (JTc-D) and Tpeak-end dispersion (T... |
13,560 | Determinants of patient survival rate after implantation of a cardioverter-defibrillator without resynchronisation capability. | Proper selection of patients at high risk for sudden cardiac death (SCD) and increasing use of implantable cardioverter-defibrillators (ICD) may contribute to improved survival among patients at the highest SCD risk.</AbstractText>To assess patient survival rate after implantation of an ICD without resynchronisation ca... |
13,561 | How to manage antiplatelet therapy for stenting in a patient requiring oral anticoagulants. | The optimal antiplatelet regimen for patients on oral anticoagulants undergoing coronary stenting continues to be controversial. It is not an insignificant problem, as 5-7 % of patients undergoing stenting are on oral anticoagulation for atrial fibrillation, a prosthetic valve, a recent left ventricular thrombus a... |
13,562 | Prognostic value of electromagnetic QRS fragmentation in survivors of sustained ventricular tachycardia or ventricular fibrillation compared with healthy controls. | Magnet field imaging (MFI) is a noninvasive method to determine cardiac electromagnetic activity.</AbstractText>This study aims to compare the electromagnetic QRS fragmentation index (eQFI) in survivors of sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) to healthy individuals.</AbstractText>Twen... |
13,563 | Altered HCN4 channel C-linker interaction is associated with familial tachycardia-bradycardia syndrome and atrial fibrillation. | HCN4 channels are involved in generation, regulation, and stabilization of heart rhythm and channel dysfunction is associated with inherited sinus bradycardia. We asked whether dysfunctional HCN4 channels also contribute to the generation of cardiac tachyarrhythmias.</AbstractText>In a candidate gene approach, we scree... |
13,564 | A case-matched comparative study of surgical radiofrequency (RF) ablation for patients with persistent or long-standing atrial fibrillation undergoing concomitant heart surgery. | Recent guidelines from the European Society of Cardiology suggest that surgical ablation should be considered in patients with atrial fibrillation (AF) who present for concomitant surgically correctable disease. This is a case-matched study of radiofrequency ablation during concomitant cardiac surgery versus lone surge... |
13,565 | Pneumonia: an arrhythmogenic disease? | Recent studies suggest that there is an increase in cardiovascular disease after pneumonia; however, there is little information on cardiac arrhythmias after pneumonia. The aims of this study were to assess the incidence of, and examine risk factors for, cardiac arrhythmias after hospitalization for pneumonia.</Abstrac... |
13,566 | Prevalence and prognostic significance of 'J waves' in patients experiencing ventricular fibrillation during acute coronary syndrome. | 'J waves' have been associated with idiopathic ventricular fibrillation (VF) and have also been described in patients with ischaemic VF.</AbstractText>Our aim was to determine whether inferior and/or lateral 'J waves' were associated with the occurrence of VF or in hospital mortality during acute coronary syndrome (ACS... |
13,567 | Laser extraction of pacemaker lead traversing a patent foramen ovale and the mitral valve. | Left ventricular lead misplacement is an infrequent complication of pacemaker or defibrillator lead insertion. It most commonly occurs through defects in the interatrial septum. Although patients may remain asymptomatic, the most common clinical complication is a thromboembolic event. Percutaneous technology has been d... |
13,568 | Characteristics and early and long-term outcome in patients with acute ischemic stroke and low ejection fraction. | We assessed the clinical characteristics of patients with acute ischemic stroke (AIS) with left ventricular ejection fraction (EF) ≤ 35% and investigated the association of low EF with early and long-term outcome.</AbstractText>A total of 2439 patients of the Acute Stroke Registry and Analysis of Lausanne (ASTRA... |
13,569 | FBN1 gene mutation characteristics and clinical features for the prediction of mitral valve disease progression. | Until today, FBN1 gene mutation characteristics were not compared with clinical features for the prediction of mitral valve disease progression.</AbstractText>Therefore, we conducted a study of 116 patients (53 men, 63 women aged 33 ± 15 years) with a causative FBN1 gene mutation and ≤ moderate mitral valve... |
13,570 | An alternative approach to explantation and exchange of the HeartWare left ventricular assist device. | Left ventricular assist device (LVAD) explantation and exchange is a relatively infrequent but potentially complex procedure. Patients requiring such procedures have multisystem suboptimal physiological reserve due to end-stage heart failure and are prone to complications. Less-invasive procedures are believed to facil... |
13,571 | Ruptured aortic dissection presenting with new onset atrial fibrillation. | We report this type A aortic dissection in both ascending and descending thoracic aorta presenting with new onset atrial fibrillation. CT images confirmed the final diagnosis. The mechanism may be due to compression of the left atrium by a large haematoma. |
13,572 | Wenxin Keli attenuates ischemia-induced ventricular arrhythmias in rats: Involvement of L‑type calcium and transient outward potassium currents. | Wenxin Keli is the first state‑sanctioned traditional Chinese medicine (TCM)-based antiarrhythmic drug. The present study aimed to examine whether long‑term treatment with Wenxin Keli reduces ischemia‑induced ventricular arrhythmias in rats in vivo, and if so, which mechanisms are involved. Male ra... |
13,573 | Effects of cardiac resynchronization therapy on left ventricular mass and wall thickness in mild heart failure patients in MADIT-CRT. | The effect of cardiac resynchronization therapy (CRT) on left ventricular wall thickness and left ventricular mass (LVM) is unknown.</AbstractText>To evaluate the effects of CRT on septal and posterior wall thickness (SWT and PWT) and LVM in patients with left bundle branch block (LBBB) and non-LBBB vs implantable card... |
13,574 | Physician perspectives and compliance with patient advance directives: the role external factors play on physician decision making. | Following passage of the Patient Self Determination Act in 1990, health care institutions that receive Medicare and Medicaid funding are required to inform patients of their right to make their health care preferences known through execution of a living will and/or to appoint a surrogate-decision maker. We evaluated th... |
13,575 | A case of left ventricular noncompaction accompanying fasciculo-ventricular accessory pathway and atrial flutter. | Left ventricular hypertrabeculation/noncompaction (LVHT) is an uncommon type of genetic cardiomyopathy characterized by trabeculations and recesses within the ventricular myocardium. LVHT is associated with diastolic or systolic dysfunction, thromboembolic complications, and arrhythmias, including atrial fibrillation, ... |
13,576 | Preventive effectiveness of implantable cardioverter defibrillator in reducing sudden cardiac death in the Chinese population: a multicenter trial of ICD therapy versus non-ICD therapy. | Preventive Effectiveness of Implantable Cardioverter.</AbstractText>This prospective and multicenter trial of the implantable cardioverter-defibrillator (ICD) aimed to evaluate the mortality rate (including sudden cardiac death [SCD]) and the efficacy of ICD in Chinese patients with high risk of sudden death.</Abstract... |
13,577 | Hemodynamic and metabolic parameters during prolonged cardiac arrest and reperfusion by extracorporeal circulation. | Extracorporeal membranous oxygenation (ECMO) is increasingly used in the management of refractory cardiac arrest. Our aim was to investigate early effects of ECMO after prolonged cardiac arrest. In fully anesthetized swine (48 kg, N=18) ventricular fibrillation (VF) was induced and untreated period (20 min) of cardiac ... |
13,578 | Clinical implication of mitral annular plane systolic excursion for patients with cardiovascular disease. | Mitral annular plane systolic excursion (MAPSE) has been suggested as a parameter for left ventricular (LV) function. This review describes the current clinical application and potential implications of routinely using MAPSE in patients with various cardiovascular diseases. Reduced MAPSE reflects impaired longitudinal ... |
13,579 | Use and benefits of public access defibrillation in a nation-wide network. | Automated External Defibrillators (AEDs) are known to increase survival after out-of-hospital cardiac arrest (OHCA). The aim of this study was to examine the use and benefit of public-access defibrillation (PAD) in a nation-wide network. We primarily sought to assess survival at 1 month but information about the circum... |
13,580 | Women hospitalized with atrial fibrillation: gender differences, trends and outcome from a 20-year registry in a Middle Eastern country (1991-2010). | Most of the published research on atrial fibrillation (AF) is limited to studies in the developed world and included mainly Caucasian patients. Data about women with AF among other ethnicities is very limited.</AbstractText>The aim of this study was to compare the clinical characteristics, treatment and outcome of wome... |
13,581 | [Analysis of the clinical data of patients with acute coronary syndrome complicated by hemorrhage during hospitalization]. | To investigate the clinical characteristics of patients with acute coronary syndrome suffering hemorrhage during hospitalization.</AbstractText>The clinical symptoms, diagnostic and therapeutic characteristics and in-hospital outcome of 3807 inpatients who were recruited into SINO-GRACE study in China due to acute coro... |
13,582 | Cardiac injury in refractory status epilepticus. | We sought to describe the spectrum of cardiac injury in refractory status epilepticus (RSE).</AbstractText>We reviewed all patients with RSE between 1999 and 2011 at Mayo Clinic. RSE was defined as generalized convulsive or nonconvulsive status epilepticus (SE) that continued despite initial therapies. Exclusion criter... |
13,583 | [Severe hypotension and ventricular fibrillation during combined general and epidural anesthesia in a patient on major tranquilizers]. | A 54-year-old man (height 155 cm, weight 49 kg) was scheduled for retroperitoneoscopic nephrectomy. He had a history of schizophrenia that had been controlled with propericiazine 10 mg and bromperidol 3 mg daily for 34 years. After induction of anesthesia, 1% mepivacaine 5 ml was administered via an epidural catheter. ... |
13,584 | Electrocardiographic abnormalities in medically screened military aircrew. | The European Society of Cardiology (ESC) recently published its updated recommendations for electrocardiogram (ECG) interpretation in athletes. It distinguishes ECG changes related to physical training (group 1 abnormalities) from training-unrelated changes (group 2) which may represent underlying electrical and struct... |
13,585 | Signal-averaged and standard electrocardiography in patients with newly diagnosed epilepsy. | Antiepileptic drugs (AEDs) have been associated with cardiac conduction abnormalities and arrhythmias, predominantly in patients with predisposing cardiac conditions. Ventricular late potentials (VLPs) detected in the signal-averaged electrocardiogram (SAECG) may imply an increased risk of ventricular tachycardia or fi... |
13,586 | Trends in survival after in-hospital cardiac arrest. | Despite advances in resuscitation care in recent years, it is not clear whether survival and neurologic function after in-hospital cardiac arrest have improved over time.</AbstractText>We identified all adults who had an in-hospital cardiac arrest at 374 hospitals in the Get with the Guidelines-Resuscitation registry b... |
13,587 | Renal sympathetic denervation provides ventricular rate control but does not prevent atrial electrical remodeling during atrial fibrillation. | Renal denervation (RDN) reduces renal efferent and afferent sympathetic activity thereby lowering blood pressure in resistant hypertension. The effect of modulation of the autonomic nervous system by RDN on atrial electrophysiology and ventricular rate control during atrial fibrillation (AF) is unknown. Here we report ... |
13,588 | Diagnosis, treatment, and outcome of giant-cell myocarditis in the era of combined immunosuppression. | Giant-cell myocarditis often escapes diagnosis until autopsy or transplantation and has defied proper treatment trials for its rarity and deadly behavior. Current therapy rests on multiple-drug immunosuppression but its prognostic influence remains poorly known. We set out to analyze (1) our experience in diagnosing gi... |
13,589 | Brugada syndrome: two decades of progress. | Two decades ago, a series of 8 idiopathic ventricular fibrillation patients who each had an abnormal ECG (right bundle branch block with coved-type ECG), but otherwise had normal hearts were described by Brugada and Brugada. Since then, the clinical entity has become known as Brugada syndrome (BS). Shortly thereafter, ... |
13,590 | Sudden cardiac arrest in ESRD patients. | End-stage renal disease (ESRD) carries a significant risk for sudden cardiac arrest (SCA), hospitalization and mortality. We present a case of a vintage hemodialysis patient who had a catastrophic event during his hemodialysis treatment - a sudden cardiac arrest. This case raises several important issues: First, patien... |
13,591 | Arrhythmogenic right ventricular cardiomyopathy: the challenge of genetic interpretation in clinically suspected cases. | This is the case of a 43-year-old Caucasian man with frequent episodes of paroxysmal atrial fibrillation (AF) and normal resting electrocardiogram (ECG), who fulfilled two minor diagnostic criteria for arrhythmogenic right ventricular cardiomyopathy (ARVC): late potentials by signal-averaged ECG and regional right vent... |
13,592 | Protective effect of K201 on isoproterenol-induced and ischemic-reperfusion-induced ventricular arrhythmias in the rat: comparison with diltiazem. | Ventricular arrhythmia (VA) is a risk for sudden death. Polymorphic ventricular tachycardia (VT) degenerating to ventricular fibrillation occurs subsequent to the prolongation of the QT interval following administration of catecholamines under Ca(2+) loading. Fatal VA also occurs in ischemia and ischemic-reperfusion. W... |
13,593 | The relationship between left ventricular scar and ventricular repolarization in patients with coronary artery disease: insights from late gadolinium enhancement magnetic resonance imaging. | The markers of ventricular repolarization corrected QT interval (QTc), QT dispersion (QTD) and Tpeak-to-Tend interval (Tpeak-end) have shown an association with sudden cardiac death (SCD) in the general population. However, their mechanistic relationship with SCD is unclear. The study aim was to evaluate the relationsh... |
13,594 | Ventricular pacing threshold after transthoracic external defibrillation with two different waveforms: an experimental study. | Although an increase in the ventricular pacing threshold (VPT) has been observed after administration of transthoracic shock for ventricular defibrillation, few studies have evaluated the phenomenon with respect to the defibrillation waveform energy. Therefore, this study examined the VPT behaviour after transthoracic ... |
13,595 | Large aneurysm of left coronary sinus of Valsalva presenting with effort-related ventricular fibrillation. | Sinus of Valsalva aneurysms are very rare and are often asymptomatic. Clinical manifestations depend on associated complications, most commonly rupture or dissection. We describe the unusual case of a 46-year old presenting with exercise-induced ventricular fibrillation due to extrinsic compression of the left coronary... |
13,596 | Hemodynamic directed CPR improves short-term survival from asphyxia-associated cardiac arrest. | Adequate coronary perfusion pressure (CPP) during cardiopulmonary resuscitation (CPR) is essential for establishing return of spontaneous circulation. The objective of this study was to compare short-term survival using a hemodynamic directed resuscitation strategy versus an absolute depth-guided approach in a porcine ... |
13,597 | What have we learned about patients with heart failure and preserved ejection fraction from DIG-PEF, CHARM-preserved, and I-PRESERVE? | Examination of patients with reduced and preserved ejection fraction in the DIG (Digitalis Investigation Group) trials and the CHARM (Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity) trials provides comparisons of outcomes in each of these types of heart failure. Comparison of the patie... |
13,598 | Diffuse ventricular fibrosis in atrial fibrillation: noninvasive evaluation and relationships with aging and systolic dysfunction. | The purpose of this study was to evaluate diffuse myocardial fibrosis of the left ventricle (LV) in patients with atrial fibrillation (AF).</AbstractText>Diffuse myocardial fibrosis is a hallmark of cardiomyopathy. Unlike replacement fibrosis, it is not visualized on delayed-enhancement cardiac magnetic resonance (CMR)... |
13,599 | [Causes of non-response to cardiac resynchronization therapy in heart failure patients with permanent atrial fibrillation]. | To evaluate the long-term effects and analyze causes of non-response to cardiac resynchronization therapy (CRT) in heart failure (HF) patients with permanent atrial fibrillation (AF).</AbstractText>Thirty-three patients with HF and AF [29 men, mean age (61 ± 10) years, NYHA class III or IV, left ventricular ejecti... |
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