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13,700 | Left atrial strain is reduced in patients with atrial fibrillation, stroke or TIA, and low risk CHADS(2) scores. | Left atrial (LA) strain as a marker for discrimination of risk for stroke and transient ischemic attack (TIA) in patients with atrial fibrillation and low-risk CHADS(2) scores (≤1) has yet to be examined.</AbstractText>Patients with atrial fibrillation, stroke or TIA, and CHADS(2) scores ≤ 1 before their ... |
13,701 | Non-linear dynamical signal characterization for prediction of defibrillation success through machine learning. | Ventricular Fibrillation (VF) is a common presenting dysrhythmia in the setting of cardiac arrest whose main treatment is defibrillation through direct current countershock to achieve return of spontaneous circulation. However, often defibrillation is unsuccessful and may even lead to the transition of VF to more nefar... |
13,702 | Distribution and clinical correlates of the interleukin receptor family member soluble ST2 in the Framingham Heart Study. | Soluble ST2 (sST2) is a cardiac biomarker whose concentration rises in response to myocardial strain. Increased sST2 concentrations may predict adverse outcomes in patients with heart failure and myocardial infarction. Because sST2 was largely undetectable with first-generation assays in ambulatory individuals, there a... |
13,703 | The effect of pinacidil on postshock activation and ventricular defibrillation threshold in canine hearts. | To determine the postshock activation patterns with both successful and failed shocks in a canine model of ventricular fibrillation, and whether piniacidil, an early after-depolarization (EAD) inhibitor, altered the defibrillation threshold (DFT) and postshock activation patterns.</AbstractText>In 6 beagles, a basket c... |
13,704 | Role of microRNAs in cardiac remodelling: new insights and future perspectives. | Cardiac remodelling is a key process in the progression of cardiovascular disease, implemented in myocardial infarction, valvular heart disease, myocarditis, dilated cardiomyopathy, atrial fibrillation and heart failure. Fibroblasts, extracellular matrix proteins, coronary vasculature, cardiac myocytes and ionic channe... |
13,705 | Hemodynamic and catecholamine changes after recurrent ventricular fibrillation. | Patients with recurrent ventricular fibrillation (VF) have a high mortality rate, which may be partly due to hemodynamic instability.</AbstractText>The aim of this study was to simulate spontaneous recurrent VF by repeated induction of VF in pigs, and to evaluate the subsequent changes in heart rate (HR), blood pressur... |
13,706 | Echocardiographic prediction of postoperative atrial fibrillation after aortic valve replacement for aortic stenosis: a two-dimensional speckle tracking left ventricular longitudinal strain multicentre pilot study. | Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery, with increased risk of embolic events, haemodynamic instability, haemorrhagic complications and prolonged hospital stay.</AbstractText>We sought to assess the value of preoperative left ventricular global longitudinal strain (GLS) ... |
13,707 | Tissue Doppler imaging and prognosis in asymptomatic or mildly symptomatic patients with hypertrophic cardiomyopathy. | Assessment of left ventricular (LV) systolic and diastolic functions by tissue Doppler imaging (TDI) has been reported to be useful for predicting the prognosis in patients with hypertrophic cardiomyopathy (HCM). The purpose of this study was to evaluate the clinical significance of TDI parameters for the prediction of... |
13,708 | MK-0448, a specific Kv1.5 inhibitor: safety, pharmacokinetics, and pharmacodynamic electrophysiology in experimental animal models and humans. | We evaluated the viability of I(Kur) as a target for maintenance of sinus rhythm in patients with a history of atrial fibrillation through the testing of MK-0448, a novel I(Kur) inhibitor.</AbstractText>In vitro MK-0448 studies demonstrated strong inhibition of I(Kur) with minimal off-target activity. In vivo MK-0448 s... |
13,709 | CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome. | Cardiovascular disease is a leading cause of death worldwide. Arrhythmias are associated with significant morbidity and mortality related to cardiovascular disease. Recent work illustrates that many cardiac arrhythmias are initiated by a pathologic imbalance between kinase and phosphatase activities in excitable cardio... |
13,710 | [Stroke and Takotsubo syndrome: a reciprocal relationship]. | Takotsubo syndrome is a transient stress cardiomyopathy associated with a distinctive left ventricular contraction pattern. It has been described as a cardioembolic source or as a consequence of stroke. Two patients are reported that illustrate the reciprocal relationship between Takotsubo syndrome and stroke and the p... |
13,711 | Left ventricular lead location and the risk of ventricular arrhythmias in the MADIT-CRT trial. | We aimed to evaluate the influence of left ventricular (LV) lead position on the risk of ventricular tachyarrhythmias in cardiac resynchronization therapy (CRT) patients.</AbstractText>Left ventricular (LV) lead position was evaluated by biplane coronary venograms and anterior/posterior, lateral chest X-rays in patient... |
13,712 | Triphasic mitral and tricuspid flows: a sign of diastolic dysfunction in a young patient with severely dilated atria and giant pulmonary veins. | This report presents a case with severe dilation of both atria and giant pulmonary veins manifested with atrial fibrillation. The following cardiac magnetic resonance findings are highly suggestive of restrictive physiology: E/A ratio greater than two, prominent A wave across the pulmonary veins and inferior vena cava,... |
13,713 | Direct comparison of percutaneous circulatory support systems in specific hemodynamic conditions in a porcine model. | Several percutaneous circulatory support systems have been recently introduced into clinical practice for the treatment of cardiogenic shock or refractory nontolerated ventricular tachycardia, in support of high-risk catheter interventions and, occasionally, cardiopulmonary resuscitation. To date, however, a direct com... |
13,714 | Automated vulnerability testing identifies patients with inadequate defibrillation safety margin. | Implantable cardioverter-defibrillator system efficacy is tested at implant by induction of ventricular fibrillation (VF). Defibrillation safety margin can be assessed without VF induction using upper limit of vulnerability methods, but these methods have required manual determination of T-wave timing.</AbstractText>To... |
13,715 | Mortality and morbidity in cardiac resynchronization patients: impact of lead position, paced left ventricular QRS morphology and other characteristics on long-term outcome. | To investigate the effect of implantation-related characteristics, especially lead position and left ventricular (LV)-paced QRS morphology, on long-term mortality and morbidity in cardiac resynchronization therapy (CRT) patients.</AbstractText>The study retrospectively analysed 362 consecutive patients who underwent CR... |
13,716 | Atrial fibrillation following autologous stem cell transplantation in patients with multiple myeloma: incidence and risk factors. | Atrial fibrillation (AF) often develops in patients with multiple myeloma following autologous stem cell transplantation (ASCT), but the exact incidence of, and the risk factors for AF have not been described. In this study, we sought to determine the incidence of AF in patients with multiple myeloma undergoing ASCT.</... |
13,717 | Serum and dietary magnesium and incidence of atrial fibrillation in whites and in African Americans--Atherosclerosis Risk in Communities (ARIC) study. | Low serum magnesium (Mg) has been associated with an increased risk of cardiovascular disease (CVD), including ventricular arrhythmias, but the association between serum or dietary Mg and atrial fibrillation (AF) has not been investigated.</AbstractText>A total of 14,290 men and women (75% white; 53% female; mean age, ... |
13,718 | Obstructive sleep apnea and hypertrophic cardiomyopathy: a common and potential harmful combination. | Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease and is characterized by large and asymmetric septal and left ventricle hypertrophy. HCM is a cause of disability, including heart failure, atrial fibrillation, and sudden death, with an annual mortality varying from 1% to 6%. Obstructive sleep... |
13,719 | Effect of ranolazine on ventricular repolarization in class III antiarrhythmic drug-treated rabbits. | Ranolazine exhibits a synergistic effect in combination with class III drugs to suppress atrial fibrillation.</AbstractText>To investigate whether a combination therapy affects repolarization and provokes ventricular tachyarrhythmias (VT) in a sensitive model of proarrhythmia.</AbstractText>Thirty-seven rabbits were as... |
13,720 | Sevoflurane postconditioning alleviates action potential duration shortening and L-type calcium current suppression induced by ischemia/reperfusion injury in rat epicardial myocytes. | It has been proved that sevoflurane postconditioning (SpostC) could protect the heart against myocardial ischemia/reperfusion injury, however, there has been few research focused on the electrophysiological effects of SpostC. The objective of the study was to investigate the effects of SpostC on action potential durati... |
13,721 | Efficacy of catheter ablation of atrial fibrillation beyond HATCH score. | HATCH score is an established predictor of progression from paroxysmal to persistent atrial fibrillation (AF). The purpose of this study was to determine if HATCH score could predict recurrence after catheter ablation of AF.</AbstractText>The data of 488 consecutive paroxysmal AF patients who underwent an index circumf... |
13,722 | Home monitoring system improves the detection of ventricular arrhythmia and inappropriate shock. | The impact of home monitoring system in the early detection of ventricular arrhythmia and inappropriate shock in daily work is not clear. The aim of this study was to investigate the impact of home monitoring system on the early detection of ventricular arrhythmia and inappropriate shock in daily clinical practice.</Ab... |
13,723 | Endurance exercise training normalizes repolarization and calcium-handling abnormalities, preventing ventricular fibrillation in a model of sudden cardiac death. | The risk of sudden cardiac death is increased following myocardial infarction. Exercise training reduces arrhythmia susceptibility, but the mechanism is unknown. We used a canine model of sudden cardiac death (healed infarction, with ventricular tachyarrhythmias induced by an exercise plus ischemia test, VF+); we previ... |
13,724 | Ventricular tachycardia/fibrillation early after defibrillator implantation in patients with hypertrophic cardiomyopathy is explained by a high-risk subgroup of patients. | Implantable cardioverter-defibrillator (ICD) studies in patients with coronary artery disease report higher risk of ventricular tachycardia/fibrillation (VT/VF) early post-implant, potentially related to local proarrhythmic effects of ICD leads.</AbstractText>To characterize early and long-term risk of ICD discharge fo... |
13,725 | Gender-related differences in patients with acute heart failure: management and predictors of in-hospital mortality. | Gender-related differences in clinical phenotype, in-hospital management and prognosis of acute heart failure (AHF) patients have been previously reported in European and US registries. The ALARM-HF survey is the first to include a cohort of 4953 patients hospitalized for AHF in 666 hospitals in 6 European countries, M... |
13,726 | Effects of ganglionated plexi ablation on ventricular electrophysiological properties in normal hearts and after acute myocardial ischemia. | Ganglionated plexi (GP) ablation has been shown to play an important role in atrial fibrillation (AF) initiation and maintenance. Also, GP ablation increases chances for prevention of AF recurrence. This study investigated the effects of GP ablation on ventricular electrophysiological properties in normal dog hearts an... |
13,727 | Development of a method to risk stratify patients with heart failure for 30-day readmission using implantable device diagnostics. | The aim of the present study was to evaluate whether diagnostic data collected after a heart failure (HF) hospitalization can identify patients with HF at risk of early readmission. The diagnostic data from cardiac resynchronization therapy defibrillator (CRT-D) devices can identify outpatient HF patients at risk of fu... |
13,728 | Genetic variants of the renin-angiotensin-aldosterone system and reverse remodeling after cardiac resynchronization therapy. | Reverse remodeling (RR) after cardiac resynchronization therapy (CRT) is associated with favorable clinical outcomes in heart failure (HF). The renin-angiotensin-aldosterone system (RAAS) is involved in the remodeling process.</AbstractText>We assessed the association between RR and 8 common RAAS gene variants, which w... |
13,729 | Abnormal Left Ventricular Filling and Postoperative Atrial Fibrillation After Cardiac Surgery. | <b>Objective:</b> Diastolic dysfunction has been associated with the development of atrial fibrillation (AF) in the community and recently in the postoperative setting. We hypothesized that abnormal left ventricular filling predicts AF after cardiac surgery, a common marker of poor outcomes. <b>Methods:</b> Cohort stud... |
13,730 | Impact of Atrial Fibrillation on Coronary Blood Flow: A Systematic Review. | Patients with atrial fibrillation (AF) frequently present with symptoms suggestive of myocardial isch- aemia, even in the absence of significant CAD, that seem to be attributable to abnormalities of myocardial perfusion and perfusion reserve. According to the results of recent human and previous experimen- tal studies ... |
13,731 | Acute myocardial infarction with a left main trunk lesion and documented lambda-like J waves. | We herein describe a case of a myocardial infarction, in which Lambda-like J waves were documented. The patient was referred to our hospital due to ventricular fibrillation. The twelve-lead electrocardiogram (ECG) on admission showed prominent J waves in the lateral and precordial leads. Coronary angiography revealed 9... |
13,732 | Use of cardiocerebral resuscitation or AHA/ERC 2005 Guidelines is associated with improved survival from out-of-hospital cardiac arrest: a systematic review and meta-analysis. | To determine whether the use of cardiocerebral resuscitation (CCR) or AHA/ERC 2005 Resuscitation Guidelines improved patient outcomes from out-of-hospital cardiac arrest (OHCA) compared to older guidelines.</AbstractText>Systematic review and meta-analysis.</AbstractText>MEDLINE, EMBASE, Web of Science and the Cochrane... |
13,733 | Nationwide improvements in survival from out-of-hospital cardiac arrest in Japan. | Little is known about the nationwide trend in the survival of out-of-hospital cardiac arrest (OHCA) in Japan and the differences in incidence and survival by age group and origin of arrest.</AbstractText>A nationwide, prospective, population-based observation covering the whole population of Japan and involving consecu... |
13,734 | Implantation and follow-up of totally subcutaneous versus conventional implantable cardioverter-defibrillators: a multicenter case-control study. | The approval of an entirely subcutaneous implantable-cardioverter defibrillator (ICD) system (S-ICD) has raised attention about this promising technology. It was developed to overcome lead failure and infection problems of conventional transvenous ICD systems. Nevertheless, lead migration of the initial design and inap... |
13,735 | Current is better than energy as predictor of success for biphasic defibrillatory shocks in a porcine model of ventricular fibrillation. | The evidence that monophasic defibrillation success is mainly determined by current is secure. However, modern defibrillators use biphasic waveforms. The aim of this study was to compare energy, peak voltage and peak current in predicting biphasic shock success in a porcine model of ventricular fibrillation (VF) where ... |
13,736 | ECG manifestations in acute organophosphorus poisoning. | A cross-sectional study was conducted to evaluate the electrocardiographic changes in 107 patients of acute organophosphorus poisoning admitted at casuality ward of MGM Medical College, Kisanganj from June 2007 to June 2010. Electrocardiographic changes were recorded before the administration of atropine. Prolonged Q-T... |
13,737 | Different types of long-duration ventricular fibrillation: can they be identified by electrocardiography. | We tested the hypothesis that after 2 minutes of ventricular fibrillation (VF), periods of highly organized activations occur on the endocardium, arising from an intramural mother rotor or triggered activity originating in the Purkinje fibers. In 6 anesthetized dogs, we recorded electrically induced VF from two-thirds ... |
13,738 | Defibrillation threshold varies during different stages of ventricular fibrillation in canine hearts. | Recent studies have shown that short duration ventricular fibrillation (SDVF) and long duration ventricular fibrillation (LDVF) are maintained by different mechanisms. The objective of this study is to evaluate how the defibrillation threshold (DFT) varies over the duration of fibrillation since the mechanism of VF mai... |
13,739 | [Totally subcutaneous defibrillator]. | The implantable cardioverter-defibrillators (ICD) is a therapy for the prevention of sudden cardiac death. Complications with implant have been associated mainly with transvenous lead insertion. Difficulties in achieving venous access can occasionally result in failed ICD implantation. Lead failures remains a major lim... |
13,740 | Prediction of mortality in clinical practice for medicare patients undergoing defibrillator implantation for primary prevention of sudden cardiac death. | The aim of this study was to derive and validate a practical risk model to predict death within 4 years of primary prevention implantable cardioverter-defibrillator (ICD) implantation.</AbstractText>ICDs for the primary prevention of sudden cardiac death improve survival, but recent data suggest that a patient subset w... |
13,741 | Left ventricular midwall fibrosis as a predictor of mortality and morbidity after cardiac resynchronization therapy in patients with nonischemic cardiomyopathy. | The aim of this study was to determine whether left ventricular (LV) midwall fibrosis, detected by midwall hyperenhancement (MWHE) on late gadolinium enhancement cardiovascular magnetic resonance (CMR) imaging, predicts mortality and morbidity in patients with dilated cardiomyopathy (DCM) undergoing cardiac resynchroni... |
13,742 | Association of KCNE1 genetic polymorphisms with atrial fibrillation in a Chinese Han population. | The purpose of this study was to investigate the association of the polymorphisms of the KCNE1 gene with atrial fibrillation (AF) in a Chinese Han population.</AbstractText>Three hundred seven AF patients and 330 age- and sex-matched controls were genotyped using the polymerase chain reaction-restriction fragment lengt... |
13,743 | Should we use automated external defibrillators in hospital wards? | Automated external defibrillators (AEDs) have shown to improve survival after cardiopulmonary arrest (CPA) in many, but not all clinical settings. A recent study reported that the use of AEDs in-hospital did not improve survival. The current retrospective study reports the results of an in-hospital AED programme in a u... |
13,744 | Permanent left atrial pacing therapy may improve symptoms in heart failure patients with preserved ejection fraction and atrial dyssynchrony: a pilot study prior to a national clinical research programme. | Our group has recently shown that in some patients, heart failure with preserved ejection fraction (HFPEF) may be explained by 'atrial dyssynchrony syndrome' (ADS) due to interatrial conduction delay (IACD), a short left atrioventricular interval (LAVI), and increased left atrial (LA) stiffness. Our primary objective w... |
13,745 | Can dexmedetomidine be a safe and efficacious sedative agent in post-cardiac surgery patients? a meta-analysis. | The aim of this study was to explore the use of dexmedetomidine as a safe and efficacious sedative agent in post-cardiac surgery patients.</AbstractText>A systematic literature search of MEDLINE, EMBASE, the Cochrane Library and Science Citation Index until January 2012 and review of studies was conducted. Eligible stu... |
13,746 | [Effects and the mechanisms of cardiac short-term memory on cellular electrical excitability]. | Electrical instability easily induces a unidirectional conduction block, resulting in ventricular tachycardia (VT) or even fibrillation (VF). Cardiac memory affects dynamic electrical characteristics through previous pacing so that it makes the memory important in arrhythmia study. This paper investigates the impact of... |
13,747 | Realities of biomedical product liability suits and the role of junk science: from breast implants to TASER weapons. | In the summer of 2006, manufacturers of a simple respirator mask costing US$1 told the U.S. Congress that Americans would find a shortage of these masks if there was another flu pandemic. The reason for this was that suing the makers of these dust masks became a major business for trial lawyers. By 2006, there had been... |
13,748 | Irregular rhythm adversely influences calcium handling in ventricular myocardium: implications for the interaction between heart failure and atrial fibrillation. | Despite adequate rate control, the combination of atrial fibrillation with heart failure (HF) has been shown, in a number of studies, to hasten HF progression. In this context, we aimed to test the hypothesis that an irregular ventricular rhythm causes an alteration in ventricular cardiomyocyte excitation-contraction c... |
13,749 | Cardiac arrhythmias in adult patients with asthma. | The pathogenesis of cardiac arrhythmias in asthma patients has not been fully elucidated. Adverse drug effects, particularly those of β2-mimetics, may play a role. The aim of this study was to determine whether asthma is associated with the risk of cardiac arrhythmias and electrocardiographic characteristics of a... |
13,750 | [The clinical usefulness of RAAS inhibitors in hypertensive patients]. | Many kinds of antihypertensive drugs have been used recently. JSH2009 supported that we should prescribe one of these drugs [calcium channel blockers, angiotensin receptor blockers (ARBs), angiotensin-converting enzyme (ACE) inhibitors, diuretics and beta-adrenergic blockers] for hypertensive patients at first. In this... |
13,751 | Arrhythmias in pulmonary arterial hypertension. | Cardiac arrhythmias are important contributors to morbidity and mortality in patients with pulmonary arterial hypertension (PAH). Such patients manifest a substrate resulting from altered autonomics, repolarization abnormalities, and ischemia. Supraventricular arrhythmias such as atrial fibrillation and flutter are ass... |
13,752 | [Isolated noncompaction cardiomyopathy with special emphasis on arrhythmia complications]. | Isolated noncompaction cardiomyopathy (NCCM) is a rare genetically determined myocardial disease caused by abnormal fetal development of the myocardium resulting in a thin compacted and a thicker noncompacted layer of the affected left ventricular (LV) wall. The genetic basis of NCCM is heterogenous. Diagnosis can be m... |
13,753 | Intracardiac echocardiographic diagnosis of thrombus formation in the left atrial appendage: a complementary role to transesophageal echocardiography. | We sought to develop and validate an intracardiac echocardiography (ICE) imaging strategy for evaluation of left atrial (LA) appendage (LAA) anatomy and function to clarify equivocal findings of LAA thrombus with transesophageal echocardiography (TEE).</AbstractText>A total of 56 patients with ICE imaging of the LAA fo... |
13,754 | [Etiology of severe pulmonary hypertension--possible role of metabolic syndrome]. | In clinical practice the association between obesity and pulmonary hypertension (PH) is not rare.</AbstractText>The aim of this study was to examine the prevalence of obesity and metabolic syndrome in patients with severe PH, especially cases without significant cardiac, pulmonary or vascular causes.</AbstractText>We r... |
13,755 | [Arrhythmic storm in a patient with Brugada syndrome--an unusual case]. | Brugada syndrome is characterized by episodes of near sudden death or syncope. The heart is normal on physical, angiographic and echocardiographic examination. The characteristic ECG abnormalities consist of ST-segment elevation in leads V1-V3 and pseudo right bundle branch block. The ECG changes can be transient, caus... |
13,756 | Efficacy and safety of implantable cardiac defibrillators for treatment of ventricular arrhythmias in patients with cardiac sarcoidosis. | Implantable cardiac defibrillator (ICD) implantation is a class IIA recommendation for patients with cardiac sarcoidosis (CS). However, little is known about the efficacy and safety of ICDs in this population. The goal of this multicentre retrospective data review was to evaluate the efficacy and safety of ICDs in pati... |
13,757 | Nodal recovery, dual pathway physiology, and concealed conduction determine complex AV dynamics in human atrial tachyarrhythmias. | The genesis of complex ventricular rhythms during atrial tachyarrhythmias in humans is not fully understood. To clarify the dynamics of atrioventricular (AV) conduction in response to a regular high-rate atrial activation, 29 episodes of spontaneous or pacing-induced atrial flutter (AFL), covering a wide range of atria... |
13,758 | Tachycardia-induced cardiomyopathy. | Tachycardia-induced cardiomyopathy (TIC) is an important cause of heart failure as it is potentially reversible after ventricular rate control. A 66-year-old hypertensive woman presented with a 15-day history of tachycardia, dyspnoea and oedema. ECG revealed atrial fibrillation with ventricular frequency of 130 beats p... |
13,759 | Cardiac arrests in schools: assessing use of automated external defibrillators (AED) on school campuses. | Sudden cardiac arrest in schools are infrequent, but emotionally charged events. The purpose of our study was to: (1) describe characteristics and outcomes of school cardiac arrests; and (2) assess the feasibility of conducting school bystander interviews to describe the events surrounding cardiac arrests, assess AED a... |
13,760 | Retrospective evaluation of current-based impedance compensation defibrillation in out-of-hospital cardiac arrest. | Transthoracic impedance (TTI) is a principal parameter that influences the intracardiac current flow and defibrillation outcome. In this study, we retrospectively evaluated the performance of current-based impedance compensation defibrillation in out-of-hospital cardiac arrest (OHCA) patients.</AbstractText>ECG recordi... |
13,761 | Elevated pulmonary artery systolic pressures are associated with a lower risk of atrial fibrillation following lung transplantation. | Atrial fibrillation (AF) is common after open-chest procedures, but the etiology remains poorly understood. Lung transplant procedures allow for the study of novel contributing factors.</AbstractText>Records of lung transplant procedures performed at a single center between 2002 and 2009 were reviewed.</AbstractText>Of... |
13,762 | Immediate impact of successful percutaneous mitral valve commissurotomy on echocardiographic measures of right ventricular contractility. | Functional analysis of the right ventricle cannot be reliably evaluated by conventional echocardiography, because of its complex geometry and load dependence of ejection phase indices. The Tei index, dP/dt, and myocardial acceleration during isovolumic contraction are parameters of right ventricular (RV) contractility ... |
13,763 | [Management of arrhythmia in patients with arterial hypertension]. | We estimated the risk of arrhythmic complications after the use of cardiovascular medications in a prospective study including 123 patients with arterial hypertension and recurrent atrial fibrillation. Dispersion characteristics of P wave and QT interval were studied in patients with left ventricular concentric remodel... |
13,764 | Initial experience with Pomerantzeff's technique for reduction of the size of giant left atrium. | The most common indication for surgical correction of giant left atrium is associated with mitral valve insufficiency with or without atrial fibrillation. Several techniques for this purpose are already described with varying results.</AbstractText>To present the initial experience with the tangential triangular resect... |
13,765 | QT variability paradox after premature ventricular contraction in patients with structural heart disease and ventricular arrhythmias. | Increased repolarization lability is known to be associated with the risk of ventricular tachycardia (VT)/ventricular fibrillation (VF). Premature ventricular contractions (PVCs) are excluded from the analysis of QT variability. However, QT dynamics after PVCs is poorly understood.</AbstractText>We analyzed data of 33 ... |
13,766 | Assessment of ventricular electrophysiological characteristics at periinfarct zone of postmyocardial infarction in rabbits following stellate ganglion block. | Assessment of Ventricular Electrophysiological Characteristics.</AbstractText>The aim of this study was to investigate the characteristics of ventricular electrophysiology following stellate ganglion block (SGB) at periinfarct zone in rabbits with myocardial infarction (MI).</AbstractText>Sixty-four rabbits were random... |
13,767 | Development and safety of an exercise testing protocol for patients with an implanted cardioverter defibrillator for primary or secondary indication. | Performing exercise tests in patients with an implantable cardioverter defibrillator (ICD) presents specific challenges because of susceptibility to ventricular arrhythmias during maximal levels of exertion. The purpose of this paper is to outline the exercise testing protocol from the Anti-Arrhythmic Effects of Exerci... |
13,768 | [Do the guidelines always show us the ideal treatment of patients for cardiac resynchronisation therapy?]. | We present a case of 80-year-old man with chronic atrial fibrillation and heart failure with mildly depressed left ventricular ejection fraction who deteriorated after implantation of pacemaker to right ventricular apex. The patient improved when pacemaker was upgraded to resynchronisation therapy (CRT). The question i... |
13,769 | May dual-source computed tomography angiography replace invasive coronary angiography in the evaluation of patients referred for valvular disease surgery? | Coronary computed tomography (CT) angiography is currently the only alternative to invasive angiography in the evaluation of coronary anatomy. In patients referred for valvular or thoracic aortic disease surgery, invasive coronary angiography remains the gold standard required by cardiac surgeons during the preoperativ... |
13,770 | Prognosis of different types of atrial fibrillation in the primary angioplasty era. | Atrial fibrillation (AF) has been associated with a poor prognosis in patients with ST-segment elevation myocardial infarction. There is considerable controversy regarding the prognostic implications of different types of AF.</AbstractText>We analyzed 913 patients consecutively admitted to our center with ST-segment el... |
13,771 | Endocardial mapping and catheter ablation for ventricular fibrillation prevention in Brugada syndrome. | Endocardial Mapping and Ablation of Brugada Syndrome.</AbstractText>Brugada syndrome (BS) is characterized by ST-segment elevation in the right precordial electrocardiogram (ECG) leads and episodes of ventricular fibrillation (VF). This study aimed to observe the feasibility of substrate modification by radiofrequency ... |
13,772 | A case of long QT syndrome having compound mutations of <i>KCNH2</i> and <i>SCN5A</i>. | Long QT syndrome (LQTS) is a hereditary ion channelopathy resulting in prolonged cardiac repolarization and abnormal prolongation of the QT interval on the electrocardiogram (ECG). The patients are likely to develop ventricular arrhythmias and sudden cardiac death. Molecular biology and basic electrophysiology studies ... |
13,773 | Severe arrhythmia after lithium intoxication in a patient with bipolar disorder admitted to the intensive care unit. | Despite its narrow therapeutic index, lithium remains widely used as a mood stabilizer for the treatment of bipolar disease. The cardiac side-effects of lithium have been well documented, and may induce non-specific T-wave flattening, prolonged QT interval, sinus node dysfunction and also ventricular tachycardia and ve... |
13,774 | Role of ventricular rate response on dementia in cognitively impaired elderly subjects with atrial fibrillation: a 10-year study. | The role of ventricular rate response (VRr) on the incidence of dementia in elderly subjects with cognitive impairment and atrial fibrillation (AF) is not known. Thus, we examined the ability of VRr to predict dementia in cognitively impaired elderly subjects with and without AF.</AbstractText>A total of 358 cognitivel... |
13,775 | Pre-hospital body surface potential mapping improves early diagnosis of acute coronary artery occlusion in patients with ventricular fibrillation and cardiac arrest. | To determine whether 80-lead body surface potential mapping (BSPM) improves detection of acute coronary artery occlusion in patients presenting with out-of-hospital cardiac arrest (OHCA) due to ventricular fibrillation (VF) and who survived to reach hospital.</AbstractText>Of 645 consecutive patients with OHCA who were... |
13,776 | The effect of the AED and AED programs on survival of individuals, groups and populations. | The automated external defibrillator (AED) is a tool that contributes to survival with mixed outcomes. This review assesses the effectiveness of the AED, consistencies and variations among studies, and how varying outcomes can be resolved.</AbstractText>A worksheet for the International Liaison Committee on Resuscitati... |
13,777 | Low doses of ranolazine and dronedarone in combination exert potent protection against atrial fibrillation and vulnerability to ventricular arrhythmias during acute myocardial ischemia. | Coronary artery disease carries dual risk for atrial tachyarrhythmias and sudden cardiac death.</AbstractText>To examine whether low-dose ranolazine and/or dronedarone can protect against vulnerability to atrial fibrillation (AF) and ventricular tachyarrhythmias.</AbstractText>In chloralose-anesthetized, open-chest Yor... |
13,778 | Atrial fibrillation pacing decreases intravascular shear stress in a New Zealand white rabbit model: implications in endothelial function. | Atrial fibrillation (AF) is characterized by multiple rapid and irregular atrial depolarization, leading to rapid ventricular responses exceeding 100 beats per minute (bpm). We hypothesized that rapid and irregular pacing reduced intravascular shear stress (ISS) with implication to modulating endothelial responses. To ... |
13,779 | Effects of propofol on ischemia-induced ventricular arrhythmias and mitochondrial ATP-sensitive potassium channels. | To investigate the potential of propofol in suppressing ventricular arrhythmias and to examine whether mitochondrial ATP-sensitive potassium channels are involved.</AbstractText>Male Sprague-Dawley rats were pretreated with intravenous infusion of propofol (Prop), a selective mitochondrial KATP channel inhibitor 5-hydr... |
13,780 | [Predictors of reversion to sinus rhythm previous to electrical cardioversion in patients with persistent atrial fibrillation treated with anti-arrhythmic drugs]. | Some patients with persistent atrial fibrillation treated pharmacologically revert to sinus rhythm prior to electrical cardioversion. Knowledge of factors predicting this effect may be clinically useful.</AbstractText>Data were obtained from patients enrolled in the study REgistro sobre la cardioVERSión en Espa&#x... |
13,781 | Relationship between mean platelet volume and coronary blood flow in patients with atrial fibrillation. | Atrial fibrillation (AF) is associated with impaired coronary flow by means of Thrombolysis in Myocardial Infarction (TIMI) frame count (TFC). Mean platelet volume (MPV) is elevated in patients with AF. In the present study we aimed to investigate the relationship between MPV and TFC in patients with AF in the absence ... |
13,782 | Two axial-flow Synergy Micro-Pumps as a biventricular assist device in an ovine animal model. | This study investigated the use of 2 Synergy Micro-Pumps for full biventricular assist device (BiVAD) support. We examined right-sided and left-sided hemodynamic parameters over a range of right-sided and left-sided pump speeds in an acute, fibrillating, non-beating-heart model in sheep.</AbstractText>Five juvenile she... |
13,783 | The cardiocerebral resuscitation protocol for treatment of out-of-hospital primary cardiac arrest. | Out-of-hospital cardiac arrest (OHCA) is a significant public health problem in most westernized industrialized nations. In spite of national and international guidelines for cardiopulmonary resuscitation and emergency cardiac care, the overall survival of patients with OHCA was essentially unchanged for 30 years--from... |
13,784 | Effects of hypothermia on brain injury assessed by magnetic resonance imaging after cardiopulmonary resuscitation in a porcine model of cardiac arrest. | To evaluate the effects of hypothermia on cerebral edema and metabolism, a porcine model of cardiac arrest was assessed by magnetic resonance imaging during the first 72 hours after restoration of spontaneous circulation (ROSC).</AbstractText>Ventricular fibrillation was induced in 33 pigs. After 8 minutes of untreated... |
13,785 | Risk stratification in Wolff-Parkinson-White syndrome: the correlation between noninvasive and invasive testing in pediatric patients. | In Wolff-Parkinson-White (WPW) syndrome, rapid antegrade conduction of atrial tachyarrhythmias can result in ventricular fibrillation and sudden death. Antegrade conduction can be assessed through noninvasive testing or invasive electrophysiology study (EPS). We aimed to determine the correlation between noninvasive te... |
13,786 | Pharmacologic rate versus rhythm-control strategies in atrial fibrillation: an updated comprehensive review and meta-analysis. | In patients with atrial fibrillation (AF), ventricular rate control with medications has been found to be noninferior in preventing clinical events, compared to a strategy converting patients to sinus rhythm and maintaining it with medications. Guidelines have accepted rate control as an acceptable therapeutic option. ... |
13,787 | The predictive value of P-wave duration by signal-averaged electrocardiogram in acute ST elevation myocardial infarction. | The prognostic value of P-wave duration has been previously evaluated by signal-averaged ECG (SAECG) in patients with various arrhythmias not associated with acute myocardial infarction (AMI).</AbstractText>To investigate the clinical correlates and prognostic value of P-wave duration in patients with ST elevation AMI ... |
13,788 | Radiofrequency catheter ablation for unifocal premature ventricular complexes triggering recurrent ventricular fibrillations in a young man without structural heart disease. | A 17-year-old man was referred for aborted sudden cardiac death. Ventricular fibrillation (VF) was recorded by automated external defibrillator. Post-resuscitation electrocardiograms showed frequent monomorphic premature ventricular complexes (PVCs), with left bundle branch block configuration and inferior axis. Cardia... |
13,789 | The impact of height on the risk of atrial fibrillation: the Cardiovascular Health Study. | Atrial fibrillation (AF) is the most common sustained arrhythmia. Increased body size has been associated with AF, but the relationship is not well understood. In this study, we examined the effect of increased height on the risk of AF and explore potential mediators and implications for clinical practice.</AbstractTex... |
13,790 | Establishing a donation after cardiac death model in pigs. | Due to the lack of human donors, several strategies have sought to expand the organ pool. Efforts to characterize donation after cardiac death (DCD) have included studies of cell viability, histological and immunohistochemical changes, and oxidative stress, which is known to negatively impact graft survival. A large an... |
13,791 | Race and improvements in the use of guideline-recommended therapies for patients with heart failure: findings from IMPROVE HF. | Race is associated with differences in use of guideline-recommended therapies for patients with heart failure (HF).</AbstractText>To evaluate whether a practice-based performance improvement intervention is associated with similar improvements in evidence-based care for black, white, and race-undocumented patients.</Ab... |
13,792 | Cardiac electrophysiology in mice: a matter of size. | Over the last decade, mouse models have become a popular instrument for studying cardiac arrhythmias. This review assesses in which respects a mouse heart is a miniature human heart, a suitable model for studying mechanisms of cardiac arrhythmias in humans and in which respects human and murine hearts differ. Section I... |
13,793 | Peri-atrial epicardial adipose tissue is associated with new-onset nonvalvular atrial fibrillation. | Atrial fibrillation (AF) is associated with considerable morbidity and mortality in patients with coronary artery disease (CAD). Epicardial adipose tissue (EAT) is recognized as an important inflammatory tissue that may exert deleterious effects on the adjacent left atrial (LA) wall. Multidetector computed tomography (... |
13,794 | Increased susceptibility to ischemia-induced ventricular tachyarrhythmias in depressed rats: Involvement of reduction of connexin 43. | Connexin 43 (Cx43) has been reported to contribute to the occurrence of ventricular arrhythmias during myocardial ischemia (MI). In this study, we investigated the expression of Cx43 and the incidences of ventricular tachyarrhythmias [i.e., ventricular tachycardia (VT) and ventricular fibrillation (VF)] during acute MI... |
13,795 | Coronary subclavian steal syndrome causing acute myocardial infarction in a patient undergoing coronary-artery bypass grafting. | Coronary subclavian steal syndrome with retrograde blood flow in the left internal mammary-coronary bypass graft is a rare but severe complication of cardiac surgery. The authors present a case of a 68-year-old man after coronary-artery bypass grafting using an internal mammary artery. He had been suffering from angina... |
13,796 | Comparison of outcomes after use of biphasic or monophasic defibrillators among out-of-hospital cardiac arrest patients: a nationwide population-based observational study. | The use and popularity of the biphasic waveform defibrillator as a replacement for the monophasic waveform defibrillator are increasing, but it is unclear whether this can improve the rate of survival among out-of-hospital cardiac arrest patients. This study aimed to verify the hypothesis that the outcome of out-of-hos... |
13,797 | Feasibility of defibrillation and automatic arrhythmia detection using an exclusively subcutaneous defibrillator system in canines. | This study reports the experimental process leading to development of an automatic totally subcutaneous implantable cardioverter defibrillator (SICD) system engineered for human use.</AbstractText>Two studies were conducted to test defibrillation and detection feasibility of an SICD system located in the left chest. In... |
13,798 | Spontaneous primary intraventricular hemorrhage: clinical features and early outcome. | Purpose. Primary hemorrhage in the ventricular system without a recognizable parenchymal component is very rare. This single-center retrospective study aimed to further characterize the clinical characteristics and early outcome of this stroke subtype. Methods. All patients with primary intraventricular hemorrhage incl... |
13,799 | [Recovered sudden cardiac death associated with an early repolarization syndrome: case analysis and pratical aspects]. | In this article, we report the case of a 61-year-old man who presented a cardiac arrest which has been resuscitated successfully. An early repolarization syndrome has been diagnosed by the ECG recorded the first 3 days after admission. This abnormality disappeared after that. The patient received an implantable cardiov... |
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