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13,800 | Mitraclip therapy and surgical mitral repair in patients with moderate to severe left ventricular failure causing functional mitral regurgitation: a single-centre experience. | Surgical mitral repair is the conventional treatment for severe symptomatic functional mitral regurgitation (FMR). Mitraclip therapy is an emerging option for selected high-risk patients with FMR. The aim of this study was to report the outcomes of patients who underwent a surgical mitral repair and Mitraclip therapy f... |
13,801 | Reliable porcine coronary model of chronic total occlusion using copper wire stents and bioabsorbable levo-polylactic acid polymer. | Chronic total occlusion (CTO) remains a challenge in interventional cardiology. We investigated the feasibility and reliability of copper wire stents and levo-polylactic acid (l-PLA) as a means of CTO induction in a porcine model.</AbstractText>In one group of 20 swine, copper stents were crimped on a 3.0mm angioplasty... |
13,802 | Sudden death. | Sudden death is probably the greatest challenge in modern cardiology. After reviewing its history, we describe the epidemiology of sudden death and its associated diseases. We highlight its physiopathologic aspects, including the factors that act on vulnerable myocardium triggering the final arrhythmia, mainly ventricu... |
13,803 | Heart rate control in patients with chronic atrial fibrillation and heart failure. | The goal of this study was to determine whether aggressive heart rate (HR) control in patients with both chronic atrial fibrillation (AF) and heart failure (HF) is associated with improved outcomes. HR control is one of the mainstays in management of patients with AF. However, rate control can be challenging in patient... |
13,804 | Atrial arrhythmia, triggering events and conduction abnormalities in isolated murine RyR2-P2328S hearts. | RyR2 mutations are associated with catecholaminergic polymorphic tachycardia, a condition characterized by ventricular and atrial arrhythmias. The present experiments investigate the atrial electrophysiology of homozygotic murine RyR2-P2328S (RyR2(S/S)) hearts for ectopic triggering events and for conduction abnormalit... |
13,805 | Hypertrophic cardiomyopathy mimicking acute anterior myocardial infarction associated with sudden cardiac death. | Hypertrophic cardiomyopathy is the most common genetic disease of the heart. We report a rare case of hypertrophic obstructive cardiomyopathy mimicking an acute anterior myocardial infarction associated with sudden cardiac death. The patient presented with acute ST elevation myocardial infarction and significant elevat... |
13,806 | Ventricular tachycardia in coronary artery disease. | Ventricular arrhythmias are important contributors to morbidity and mortality in patients with coronary artery disease. Ventricular fibrillation accounts for the majority of deaths occurring in the acute phase of ischemia, whereas sustained, monomorphic ventricular tachycardia due to reentry generated in the scar tissu... |
13,807 | A rare case of isolated congenital right ventricular inflow obstruction due to the presence of an intraventricular muscular shelf. | A 56-year-old man presented with anasarca and a 40-lb weight gain that had occurred over the course of 3 to 4 weeks. He had a history of permanent atrial fibrillation and a congenital anomaly of the right ventricular inflow tract. This defect consisted of a muscular shelf in the right ventricular inflow tract, which en... |
13,808 | Multiple left ventricular thrombi in a patient with left ventricular noncompaction. | The major clinical features of myocardial noncompaction are heart failure, arrhythmias, and thromboembolic events. Prominent myocardial trabeculae and deep recesses characteristic of myocardial noncompaction can cause stagnant blood flow and the formation of left ventricular clots. We describe the case of a 62-year-old... |
13,809 | The causes, treatment, and outcome of acute heart failure in 1006 Africans from 9 countries. | Acute heart failure (AHF) in sub-Saharan Africa has not been well characterized. Therefore, we sought to describe the characteristics, treatment, and outcomes of patients admitted with AHF in sub-Saharan Africa.</AbstractText>The Sub-Saharan Africa Survey of Heart Failure (THESUS-HF) was a prospective, multicenter, obs... |
13,810 | The effects of 3 different compression methods on intrathoracic pressure in a swine model of ventricular fibrillation. | The aim of this study was to provide a realistic comparison of 3 different extracorporeal compression methods during cardiopulmonary resuscitation on intrathoracic pressure (ITP), hemodynamics, and oxygen metabolism in a swine model of ventricular fibrillation (VF).</AbstractText>Eight minutes after the development of ... |
13,811 | Mild-to-moderate functional tricuspid regurgitation in patients undergoing mitral valve surgery. | The decision to repair mild-to-moderate functional tricuspid regurgitation (TR) during mitral valve surgery remains controversial. We evaluated the effects of tricuspid valve (TV) repair for functional mild-to-moderate TR during mitral valve surgery.</AbstractText>We enrolled 959 patients with mild-to-moderate function... |
13,812 | [Action potential duration restitution and the potential association with ventricular arrhythmia in Langendorff-perfused chronic heart failure rabbit hearts]. | To observe the action potential duration restitution (APDR) change and potential association with ventricular arrhythmia (VA) in Langendorff-perfused chronic heart failure rabbit hearts.</AbstractText>Male rabbits were randomly divided into two groups: control (CTL, n=15) group and chronic heart failure (CHF, n=15) gro... |
13,813 | Potassium induced cardiac standstill during conventional cardiopulmonary resuscitation in a pig model of prolonged ventricular fibrillation cardiac arrest: a feasibility study. | Potassium-based cardioplegia has been the gold standard for cardioprotection during cardiac surgery. We sought to evaluate the feasibility and the effects of potassium-induced cardiac standstill during conventional cardiopulmonary resuscitation (CPR) in a pig model of prolonged ventricular fibrillation (VF).</AbstractT... |
13,814 | Ivabradine but not propranolol delays the time to onset of ischaemia-induced ventricular fibrillation by preserving myocardial metabolic energy status. | Heart rate reduction (HRR) has shown a beneficial impact on the prevention of ventricular fibrillation, which could be explained by increased myocardial blood flow and preservation of mitochondrial structure. Here, we assessed the HRR impact on time to onset of ventricular fibrillation (TOVF) and myocardial metabolic e... |
13,815 | Falsely pessimistic prognosis by EEG in post-anoxic coma after cardiac arrest: the borderland of nonconvulsive status epilepticus. | Prognostication following anoxic coma relies on clinical assessment and is assisted by neurophysiology. A non-evolving EEG spike burst/isoelectric suppression pattern after the first 24 hours almost invariably indicates poor outcome, while an evolving pattern implies nonconvulsive status epilepticus (NCSE) that may "hi... |
13,816 | Load-distributing band improves ventilation and hemodynamics during resuscitation in a porcine model of prolonged cardiac arrest. | The use of mechanical cardiopulmonary resuscitation (CPR) has great potential for the clinical setting. The purpose of present study is to compare the hemodynamics and ventilation during and after the load-distributing band CPR, versus the manual CPR in a porcine model of prolonged cardiac arrest, and to investigate th... |
13,817 | Single-beat determination of global longitudinal speckle strain in patients with atrial fibrillation. | Although global left ventricular (LV) systolic function is an important determinant of outcome, the assessment of global longitudinal speckle strain (GLS) in patients with atrial fibrillation (AF) is unreliable because of beat-to-beat variation. Previous studies have confirmed that LV contractility of each irregular be... |
13,818 | Defibrillation Testing During Defibrillator Implantation. | Implantable cardioverter defibrillators (ICDs) terminate ventricular tachycardia (VT) and ventricular fibrillation (VF) with high efficacy. ICDs improve mortality in patients after survived sudden cardiac death (SCD) and in patients at high risk of dying suddenly. All trials which show a benefit of ICD therapy, have pe... |
13,819 | Risk Stratification in Atrial Fibrillation Patients - A Review Focused on Mortality. | Atrial fibrillation (AF) is associated with increased mortality that is largely due to the severe co-morbidities of patients with this rhythm disturbance rather than to its electrocardiographic features. Available evidence indicated that ageing, heart failure and stroke are the most important predictors of all-cause mo... |
13,820 | The implementation of therapeutic hypothermia in the emergency department: a multi-institution case review. | The use of therapeutic hypothermia (TH) is a burgeoning treatment modality for post-cardiac arrest patients.</AbstractText>We performed a retrospective chart review of patients who underwent post-cardiac arrest TH at eight different institutions across the United States. Our objectives were to assess how TH is currentl... |
13,821 | Effect of lesional differences in prolapsed leaflets on clinical outcomes in patients with mitral valve prolapse. | Mitral valve prolapse (MVP) is usually benign, although serious complications may occur. It remains unclear whether the region of prolapsed mitral leaflets might affect prognosis. The aim of this study was to investigate lesional differences of clinical courses of MVP.</AbstractText>We retrospectively investigated 128 ... |
13,822 | Activation of εPKC reduces reperfusion arrhythmias and improves recovery from ischemia: optical mapping of activation patterns in the isolated guinea-pig heart. | Pervious biochemical and hemodynamic studies have highlighted the important role of εPKC in cardioprotection during ischemic preconditioning. However, little is known about the electrophysiological consequences of εPKC modulation in ischemic hearts. Membrane permeable peptide εPKC selective activator ... |
13,823 | Effects of n-3 Polyunsaturated Fatty Acids on Cardiac Ion Channels. | Dietary n-3 polyunsaturated fatty acids (PUFAs) have been reported to exhibit antiarrhythmic properties, and these effects have been attributed to their capability to modulate ion channels. In the present review, we will focus on the effects of PUFAs on a cardiac sodium channel (Na(v)1.5) and two potassium channels inv... |
13,824 | J-waves in patients with an acute ST-elevation myocardial infarction who underwent successful percutaneous coronary intervention: prevalence, pathogenesis, and clinical implication. | The prevalence, clinical significance, and pathogenesis of J-waves were studied in the patients with an ST-elevation myocardial infarction (MI) after percutaneous coronary intervention (PCI).</AbstractText>One hundred and fifty-two consecutive patients with an acute ST-elevation MI were included. The mean age was 68.6 ... |
13,825 | Mitral valve surgery: wait and see vs. early operation. | Mitral valve repair represents the optimal surgical treatment for severe degenerative mitral regurgitation. According to the current guidelines, mitral repair is indicated in the presence of symptoms and/or signs of left ventricular (LV) dysfunction. In asymptomatic patients with preserved LV function, surgery should b... |
13,826 | Effect of plant polyphenols on ischemia-reperfusion injury of the isolated rat heart and vessels. | In the present study, we investigated the potential protective effect of selected natural substances in a rat model of heart and mesenteric ischemia-reperfusion (I/R). Experiments were performed on isolated Langendorff-perfused rat hearts, subjected to 30-min global ischemia, followed by 30-min reperfusion. Arbutin, cu... |
13,827 | Minimally invasive hybrid ablation procedure for the treatment of persistent atrial fibrillation: one year results. | The concept of a hybrid approach, combining the most effective techniques of surgical and endocardial catheter ablation has resulted in the creation of the convergent ablation procedure. This novel, pericardioscopic, hybrid approach can be an effective option for highly symptomatic patients with persistent atrial fibri... |
13,828 | The problem of indeterminate microvolt T-wave alternans results in patients with left ventricular dysfunction referred for implantable cardioverter-defibrillator implantation in the primary prevention of sudden cardiac death. | Microvolt T-wave alternans (MTWA) is a recommended noninvasive diagnostic test for predicting the risk of sudden cardiac death (SCD). However, about 6% to 41% of MTWA results are indeterminate. The causes, interpretation and clinical significance of these results have not been not clearly established.</AbstractText>To ... |
13,829 | Ibutilide decreases defibrillation threshold by the reduction of activation pattern complexity during ventricular fibrillation in canine hearts. | Ibutilide has been commonly used for pharmacologic cardioversion of atrial fibrillation and flutter in clinical settings. The objective of this study was to investigate the effects of ibutilide on the defibrillation threshold (DFT), restitution properties, dispersion of refractoriness and activation patterns during ven... |
13,830 | Thrombolysis of ischemic stroke from noncompaction in metabolic myopathy. | Ischemic stroke has not been reported together with left ventricular hypertrabeculation/noncompaction (LVHT) and metabolic myopathy.</AbstractText>In a 32-year-old woman with suspected metabolic myopathy, congenital AV-block, pacemaker implantation at the age of 20, and reduced systolic function, LVHT was detected on e... |
13,831 | Effect of matrix metalloproteinase and their inhibitors on atrial myocardial structural remodeling. | To explore the expression of matrix metalloproteinase and tissue inhibitor of metalloproteinase of atrial myocardial structure of rheumatic and coronary heart disease.</AbstractText>Fifty patients with rheumatic heart disease (RHD) undergoing artificial mitral valve replacement surgery were selected: 20 with sinus rhyt... |
13,832 | An echo state neural network for QRST cancellation during atrial fibrillation. | A novel method for QRST cancellation during atrial fibrillation (AF) is introduced for use in recordings with two or more leads. The method is based on an echo state neural network which estimates the time-varying, nonlinear transfer function between two leads, one lead with atrial activity and another lead without, fo... |
13,833 | Very long-term results (up to 17 years) with the double-orifice mitral valve repair combined with ring annuloplasty for degenerative mitral regurgitation. | The very long-term results of the double-orifice mitral valve repair are unknown. The aim of this study was to assess the late clinical and echocardiographic outcomes of this technique in patients with degenerative mitral regurgitation.</AbstractText>From 1993 to 2000, 174 patients with severe degenerative mitral regur... |
13,834 | Pediatric prehospital evaluation of NYC cardiac arrest survival (PHENYCS). | The objective of this study was to describe the demographics of out-of-hospital cardiac arrests (OOHCAs) in children younger than 18 years and characteristics associated with survival among these children in New York City (NYC).</AbstractText>A prospective observational cohort of all children younger than 18 years with... |
13,835 | Slow ventricular response atrial fibrillation related to mad honey poisoning. | Mad honey poisoning which is induced by Grayanotoxin (Andromedotoxin), is also known to have adverse effects in the cardiovascular system leading to different clinical entities. This toxin is produced by a member of the Rhododendron genus of plants of two R. Luteum and R. Panticum. In this article, we presented a case ... |
13,836 | Role for MicroRNA-21 in atrial profibrillatory fibrotic remodeling associated with experimental postinfarction heart failure. | Atrial tissue fibrosis is often an important component of the atrial fibrillation (AF) substrate. Small noncoding microRNAs are important mediators in many cardiac remodeling paradigms. MicroRNA-21 (miR-21) has been suggested to be important in ventricular fibrotic remodeling by downregulating Sprouty-1, a protein that... |
13,837 | Reasons for loss of cardiac resynchronization therapy pacing: insights from 32 844 patients. | The efficacy of cardiac resynchronization therapy (CRT) is associated with the amount of CRT pacing delivered. The specific causes of CRT pacing loss and their relative frequencies remain poorly defined.</AbstractText>CRT patients who transmitted device data from 2006 to 2011 were screened for inclusion. Device diagnos... |
13,838 | Docosahexaenoic acid, but not eicosapentaenoic acid, supplementation reduces vulnerability to atrial fibrillation. | The potential health benefits of ω-3 polyunsaturated fatty acids (PUFAs) usually are studied using a combination of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). This combination reduces vulnerability to experimentally induced atrial fibrillation (AF). It is unknown whether EPA and DHA have differen... |
13,839 | Treatment of obstructive sleep apnea in patients with cardiac arrhythmias. | Obstructive sleep apnea (OSA) is the most common form of sleep-disordered breathing that is prevalent in the population and frequently under diagnosed. Usually presenting with respiratory symptoms, the most significant consequences of OSA are cardiovascular, including arrhythmias. The pathophysiology of OSA through mul... |
13,840 | Multivisceral sarcoidosis: an unexpected finding in a water-related death. | Upon encountering a body submerged within or in close association with a watery environment, the temptation by the first responder may be to surmise that the death is probably an accidental drowning of some sort. The challenge, however, is to quickly move beyond such temptation, maintaining an open mind to other possib... |
13,841 | Factors influencing the decision to ICD implantation in survivors of OHCA and its influence on long term survival. | Knowledge is insufficient of the long-term benefit of an implantable cardioverter defibrillator (ICD) after out of hospital cardiac arrest (OHCA).</AbstractText>To describe the use and factors of importance for outcome in relation to ICD use among survivors of ventricular fibrillation (VF).</AbstractText>In consecutive... |
13,842 | Interatrial blocks. A separate entity from left atrial enlargement: a consensus report. | Impaired interatrial conduction or interatrial block is well documented but is not described as an individual electrocardiographic (ECG) pattern in most of ECG books, although the term atrial abnormalities to encompass both concepts, left atrial enlargement (LAE) and interatrial block, has been coined. In fact, LAE and... |
13,843 | Current electrocardiographic criteria for diagnosis of Brugada pattern: a consensus report. | Brugada syndrome is an inherited heart disease without structural abnormalities that is thought to arise as a result of accelerated inactivation of Na channels and predominance of transient outward K current (I(to)) to generate a voltage gradient in the right ventricular layers. This gradient triggers ventricular tachy... |
13,844 | Novel anti-arrhythmic medications in the treatment of atrial fibrillation. | Atrial fibrillation (AF) is a prevalent condition particularly amongst the elderly, which contributes to both morbidity and mortality. The burden of disease has lead to significant increases in health care utilization and cost in recent years. Treatment of Atrial fibrillation consists of either a rate or rhythm control... |
13,845 | Obesity, diabetes and atrial fibrillation; epidemiology, mechanisms and interventions. | The last few decades have witnessed a global rise in adult obesity of epidemic proportions. The potential impact of this is emphasized when one considers that body mass index (BMI) is a powerful predictor of death, type 2 diabetes (T2DM) and cardiovascular (CV) morbidity and mortality [1, 2]. Similarly we have witnesse... |
13,846 | Safety and efficacy of an ultrashort-acting β1-blocker on left ventricular dysfunction. | Landiolol hydrochloride, an ultrashort-acting β1-selective blocker, is a highly regulated drug. This study evaluated the safety and efficacy of this drug for cases of coronary artery bypass grafting (CABG) with left ventricular dysfunction. Between September 2006 and August 2009, 32 patients with a left ventricul... |
13,847 | Fibrosis, myocardial crossings, disconnections, abrupt turns, and epicardial reflections: do they play an actual role in human permanent atrial fibrillation? A controlled necropsy study. | Atrial myocardium fibrosis and other alterations of fiber continuity and potential circuit reentrancy (disconnections, abrupt turns, crossings, and epicardial reflections) are thought to play an important role in permanent atrial fibrillation. However, few studies have been performed in human beings. Some of them are o... |
13,848 | Antiarrhythmic properties of ranolazine--from bench to bedside. | Pharmacological management of cardiac arrhythmias is limited by the reduced availability of safe and effective antiarrhythmic agents.</AbstractText>Ranolazine is an agent currently used for the treatment of angina, which inhibits transmembrane ionic currents involved in several phases of the action potential in both th... |
13,849 | Epilepsy is a risk factor for sudden cardiac arrest in the general population. | People with epilepsy are at increased risk for sudden death. The most prevalent cause of sudden death in the general population is sudden cardiac arrest (SCA) due to ventricular fibrillation (VF). SCA may contribute to the increased incidence of sudden death in people with epilepsy. We assessed whether the risk for SCA... |
13,850 | Idiopathic ventricular fibrillation with fragmented QRS complex and J wave in resting electrocardiogram. | To describe the clinical characteristics of idiopathic ventricular fibrillation (IVF) with fragmented QRS complex (f-QRS) and J wave in resting electrocardiogram.</AbstractText>We reviewed data from 21 case subjects in our hospital who were resuscitated after cardiac arrest due to IVF and assessed the prevalence of f-Q... |
13,851 | Target-organ damage and cardiovascular complications in hypertensive Nigerian Yoruba adults: a cross-sectional study. | Hypertension is a major challenge to public health as it is frequently associated with sudden death due to the silent nature of the condition. By the time of diagnosis, some patients would have developed target-organ damage (TOD) and associated clinical conditions (ACC) due to low levels of detection, treatment and con... |
13,852 | Therapeutic effects of selective atrioventricular node vagal stimulation in atrial fibrillation and heart failure. | Atrial fibrillation (AF) and heart failure (HF) frequently coexist. We have previously demonstrated that selective atrioventricular node (AVN) vagal stimulation (AVN-VS) can be used to control ventricular rate during AF. Due to withdrawal of vagal activity in HF, the therapeutic effects of AVN-VS may be compromised in ... |
13,853 | [Cardiopulmonary resuscitation should continue as long as shockable cardiac rhythms persist]. | Initiation of cardiopulmonary resuscitation or termination of a resuscitation attempt may be challenging. We report a case with a 41-year-old man who was successfully resuscitated without significant neurological deficits despite more than 45 minutes of cardiac arrest with shockable cardiac rhythms. This case demonstra... |
13,854 | Up-regulation of myocardial connexin-43 in spontaneously hypertensive rats fed red palm oil is most likely implicated in its anti-arrhythmic effects. | The purpose of this study was to test our hypothesis that red palm oil (RPO) intake may affect abnormalities of myocardial connexin-43 (Cx43) and protein kinase Cε (PKCε) signaling, and consequently the propensity of the spontaneously hypertensive rat heart (SHR) heart to arrhythmias. SHR and Wistar-Kyoto (... |
13,855 | Echocardiography-guided biventricular pacemaker optimization: role of echo Doppler in hemodynamic assessment and improvement. | In spite of improvements in heart failure management and increasing utilization of cardiac resynchronization therapy (CRT), approximately 30-40% of CRT patients remain nonresponders and 50% or more are echocardiographic nonresponders (defined as less than 15% reduction in left ventricular end systolic volume post-CRT).... |
13,856 | Pacing in sinus node disease to prevent atrial fibrillation. | Cardiac pacing is the only effective treatment for patients with symptomatic sinus node disease (SND). The majority of patients with SND have several risk factors associated with development of atrial fibrillation (AF) at the time of pacemaker implantation and are therefore considered a high-risk population. Patients w... |
13,857 | Pathological changes long after liver transplantation in a familial amyloidotic polyneuropathy patient. | Liver transplantation (LT) reportedly prolongs the survival of patients with familial amyloidotic polyneuropathy (FAP), a fatal hereditary systemic amyloidosis caused by mutant transthyretin (TTR). However, what happens in systemic tissue sites long after LT is poorly understood. In the present study, we report patholo... |
13,858 | Efficacy of tuned waveforms based on different membrane time constants on defibrillation thresholds: primary results from the POWER trial. | The efficacy of tuned defibrillation waveforms versus the nominal fixed-tilt waveform has been previously studied. However, the optimal membrane time constant for tuning was not known. The POWER (Pulsewidth Optimized Waveform Evaluation tRial) trial was designed to determine the optimal membrane time constant for progr... |
13,859 | Ventricular arrhythmias in patients with implanted cardioverter defibrillators. | Implantable cardioverter-defibrillators (ICDs) are highly effective in reducing mortality related to ventricular arrhythmias. However, there is considerable morbidity associated with their use, mostly related to ICD shocks. In addition, the occurrence of arrhythmias and ICD shocks in patients with heart failure is asso... |
13,860 | Spanish Catheter Ablation Registry. 11th official report of the Spanish Society of Cardiology Working Group on electrophysiology and arrhythmias (2011). | The findings of the 2011 Spanish Catheter Ablation Registry are presented.</AbstractText>Data were collected in two ways: retrospectively using a standardized questionnaire, and prospectively from a central database. Each participating center selected its own preferred method of data collection.</AbstractText>Sixty-six... |
13,861 | Echocardiography In the Prediction of Atrial Fibrillation Recurrence: A Review. | Atrial fibrillation (AF) is a very common sustained arrhythmia. Co-morbidities and age signifi cantly accelerate the progression of AF to persistent and permanent forms and the development of complications. The rate of AF recurrence is 10% in the first year after the initial diagnosis (25-50% in the first month after r... |
13,862 | Effect of Omega-3 Polyunsaturated Fatty Acid Supplementation in Patients with Atrial Fibrillation. | Atrial fibrillation (AF) is the most common sustained atrial arrhythmia conferring a higher morbidity and mortality. Despite the increasing incidence of AF; available therapies are far from perfect. Dietary fish oils, containing omega 3 fatty acids, also called polyunsaturated fatty acid [PUFA] have demonstrated benefi... |
13,863 | Microvolt T-wave alternans in short QT syndrome. | T-wave alternans (TWA) is an accepted marker of risk for malignant ventricular arrhythmias, for which prognosis value has been established in different populations. Short QT syndrome (SQTS) is a very rare primary electrical disease carrying the risk of ventricular fibrillation. TWA in SQTS has not been evaluated yet.</... |
13,864 | Impact of the preprocedural frequency of paroxysmal atrial fibrillation on the clinical outcome after catheter ablation. | Pulmonary vein antral isolation (PVAI) is a recommended treatment for symptomatic drug-refractory paroxysmal atrial fibrillation (PAF). PAF naturally progresses toward persistent AF with an increase in the frequency and duration of AF. The objective of this study was to evaluate whether the preprocedural AF frequency h... |
13,865 | Cardiac resynchronization therapy in patients with permanent atrial fibrillation: results from the Resynchronization for Ambulatory Heart Failure Trial (RAFT). | Cardiac resynchronization (CRT) prolongs survival in patients with systolic heart failure and QRS prolongation. However, most trials excluded patients with permanent atrial fibrillation.</AbstractText>The Resynchronization for Ambulatory Heart Failure Trial (RAFT) randomized patients to an implantable cardioverter defi... |
13,866 | Severe generalised rhabdomyolysis with fatal outcome associated with isotretinoin. | Isotretinoin is considered to be a safe and effective therapy in otherwise therapy-resistant acne. Elevated serum creatine phosphokinase values with or without muscle-related symptoms in isotretinoin-treated patients have been reported and interpreted as benign phenomena, lethal cases have not been described yet. We pr... |
13,867 | Autonomic boundary conditions for ventricular fibrillation and their implications for a novel defibrillation technique. | The sympathetic and parasympathetic divisions of the autonomic nervous system modulate cardiac rhythm and the probability of arrhythmia occurrence. Both increased sympathetic drive and hypoxia increase the likelihood for ventricular fibrillation (VF). Vagus nerve stimulation (VNS) can protect from fatal arrhythmias via... |
13,868 | [Antitachyarrhythmic interventions of implantable cardioverter-defibrillator in primary and secondary sudden cardiac death prevention patients]. | Antitachycardia pacing (ATP) and high voltage interventions (CV) are methods of interrupting dangerous ventricular arrhythmias. The aim of the study was to determine the frequency of ventricular tachyarrhythmias and form of ICD interventions in patients in the primary and secondary sudden cardiac death (SCD) prevention... |
13,869 | Implantable cardioverter defibrillator with and without defibrillation threshold testing. | Defibrillation threshold (DFT) testing at the time of implantable cardioverter defibrillator (ICD) insertion is performed routinely. This practice is being reconsidered due to doubts about its ability to improve ICD efficacy and evidence that survival may not be affected by the test.</AbstractText>To compare the outcom... |
13,870 | Isoprenaline and quinidine to calm Brugada VF storm. | A 3-year-old man with an implanted cardioverter-defibrillator (ICD) for type 2 Brugada syndrome was admitted to coronary care unit with ventricular fibrillation electrical storm and consequent appropriate recurrent ICD shocks. The rhythm did not settle with conventional antiarrhythmics such as β-blockers and amio... |
13,871 | Feasibility and efficacy of electrical cardioversion after cardiac resynchronization implantation in patients with permanent atrial fibrillation. | Patients with permanent atrial fibrillation (AF) who undergo cardiac resynchronization therapy (CRT) may spontaneously recover sinus rhythm during follow-up. We tested the feasibility and efficacy of electrical cardioversion attempted after 3 months of CRT in patients with permanent AF and measured the long-term mainte... |
13,872 | Sex differences in clinical characteristics and outcomes in elderly patients with heart failure and preserved ejection fraction: the Irbesartan in Heart Failure with Preserved Ejection Fraction (I-PRESERVE) trial. | There are few sex-specific outcome data in heart failure with preserved ejection fraction.</AbstractText>We assessed sex differences in baseline characteristics and outcomes among 4128 patients with heart failure with preserved ejection fraction in the Irbesartan in Heart Failure with Preserved Ejection Fraction (I-PRE... |
13,873 | Arrhythmias in Fabry cardiomyopathy. | Prior studies suggest that the incidence of ventricular arrhythmias is high in patients with Fabry cardiomyopathy. This study evaluated the incidence of significant arrhythmias in a series of patients with Fabry cardiomyopathy.</AbstractText>Arrhythmias are important causes of morbidity and mortality in Fabry Cardiomyo... |
13,874 | Atrial fibrillation ablation and heart failure. | Atrial fibrillation (AF) worsens outcome in patients with systolic heart failure and the presence of heart failure (HF) predicts a 5- to 6-fold increase in risk of AF. In addition to loss of atrial systole, AF may contribute to left ventricular (LV) systolic dysfunction due a rapid ventricular rate, irregularity of rhy... |
13,875 | Hypothermia-induced spatially discordant action potential duration alternans and arrhythmogenesis in nonhibernating versus hibernating mammals. | The heart of hibernating species is resistant to lethal ventricular fibrillation (VF) induced by hypothermia. Spatially discordant (SDA) cardiac alternans is a promising predictor of VF, yet its role in the mechanism of hypothermic arrhythmogenesis in both nonhibernating and hibernating mammals remains unclear. We opti... |
13,876 | Risk stratification in hypertrophic cardiomyopathy: time for renewal? | Systematic clinical assessment and careful monitoring of patients with hypertrophic cardiomyopathy (HCM) can be used to identify a cohort of patients that benefit from medical intervention and almost certainly improve long-term outcomes. One of the major limitations of the current approach is a lack of predictive power... |
13,877 | [Analysis of risk factors of postoperative hemodialysis in patients undergoing off-pump coronary artery bypass grafting]. | To investigate the risk factors of postoperative hemodialysis in patients undergoing off-pump coronary artery bypass grafting (OPCAB).</AbstractText>The perioperative data of 2379 consecutive patients undergoing OPCAB from November 2007 to February 2009 were analyzed retrospectively. Patients were divided into dialysis... |
13,878 | Infiltrated cardiac lipids impair myofibroblast-induced healing of the myocardial scar post-myocardial infarction. | Lipids have been detected in the ischemic myocardium of patients' post-myocardial infarction (MI). However, their effect on the cardiac healing process remains unknown. We investigated whether intramyocardial lipids affect the signaling pathways involved in the fibrotic reparative response impairing cardiac healing pos... |
13,879 | Idiopathic ventricular fibrillation originating from the moderator band. | We report a case of a 59-year-old man with idiopathic ventricular fibrillation storm. Ventricular fibrillation was pause-dependent and triggered by an early-coupled right ventricular premature complex. The characteristic premature beat was mapped and successfully ablated from Purkinje fibers of the moderator band. |
13,880 | Six-year prospective audit of 'scoop and run' for chest-reopening after cardiac arrest in a cardiac surgical ward setting. | The aim of the study was to identify which cardiac surgical ward patients benefit from 'scoop and run' to the operating room for chest reopening.</AbstractText>In-hospital arrests in a cardiothoracic hospital were prospectively audited over a 6-year period. The following pieces of information were collected for every p... |
13,881 | Effects of pitavastatin on cardiac structure and function and on prevention of atrial fibrillation in elderly hypertensive patients: a prospective study of 2-years' follow-up. | The aim of this prospective study was to determine whether statin therapy (pitavastatin) has a beneficial effect on the prevention of new-onset atrial fibrillation (AF) in elderly patients with hypertension (HTN) and to evaluate the relationships among statin treatment, the development of AF, and left atrial (LA) and v... |
13,882 | In-hospital mortality among patients with takotsubo cardiomyopathy: a study of the National Inpatient Sample 2008 to 2009. | Takotsubo cardiomyopathy is characterized by acute, reversible left ventricular apical ballooning. Little is known about the characteristics of patients with takotsubo cardiomyopathy who have in-hospital mortality. We sought to determine in-hospital mortality rate, complication rate, and characteristics of patients wit... |
13,883 | Anatomy, mechanics, and pathophysiology of the mitral annulus. | The mitral annulus plays an important role in leaflet coaptation, in unloading mitral valve closing forces, and in promoting left atrial and left ventricular filling and emptying. Perturbations of annular mechanics figure prominently in a number of disorders including functional and ischemic mitral regurgitation, mitra... |
13,884 | Hypertrophic cardiomyopathy. | Hypertrophic cardiomyopathy is a common inherited cardiovascular disease present in one in 500 of the general population. It is caused by more than 1400 mutations in 11 or more genes encoding proteins of the cardiac sarcomere. Although hypertrophic cardiomyopathy is the most frequent cause of sudden death in young peop... |
13,885 | [Mathematical modeling of ventricular disturbances following atrial fibrillation]. | The present study presents the results of mathematical and computer modeling of atrial fibrillation and ventricular disturbances following atrial fibrillation. The model is based on the assumption, that electric impulsation arriving on the atrioventricular node during atrial fibrillation is sum N of independent pulse s... |
13,886 | Influence of acute stress on cardiac electrophysiological stability in male goats. | Stress plays an important role in the pathogenesis of ventricular arrhythmias. This study was designed to examine the effect of acute stress and metoprolol, a beta adrenergic receptor blocker, on cardiac electrophysiological stability of male goats.</AbstractText>Fifteen male goats were randomly divided into three grou... |
13,887 | Implantable cardioverter-defibrillators have reduced the incidence of resuscitation for out-of-hospital cardiac arrest caused by lethal arrhythmias. | Over the last decades, a gradual decrease in ventricular fibrillation (VF) as initial recorded rhythm during resuscitation for out-of-hospital cardiac arrest (OHCA) has been noted. We sought to establish the contribution of implantable cardioverter-defibrillator (ICD) therapy to this decline.</AbstractText>Using a pros... |
13,888 | Evaluation of injury criteria for the prediction of commotio cordis from lacrosse ball impacts. | Commotio Cordis (CC) is the second leading cause of mortality in youth sports. Impacts occurring directly over the left ventricle (LV) during a vulnerable period of the cardiac cycle can cause ventricular fibrillation (VF), which results in CC. In order to better understand the pathophysiology of CC, and develop a mech... |
13,889 | Coronary perivascular fibrosis is associated with impairment of coronary blood flow in patients with non-ischemic heart failure. | Although myocardial interstitial fibrosis has been considered to play a pathogenic role in chronic heart failure (HF), the role of perivascular fibrosis, another form of fibrosis, remains to be elucidated.</AbstractText>We examined 64 consecutive patients with non-ischemic HF caused by hypertrophic cardiomyopathy (HCM,... |
13,890 | Health-related quality of life in different clinical subgroups with typical AFL who have undergone cavo-tricuspid isthmus ablation. | To evaluate changes in health-related quality of life (HRQOL) in different sub-groups of a cohort of patients with typical atrial flutter (AFL) treated with cavotricuspid isthmus (CTI) radiofrequency catheter ablation.</AbstractText>95 consecutive patients due to undergo CTI ablation were enrolled in a study involving ... |
13,891 | [Anticoagulation in elderly patients with atrial fibrillation: from the guidelines to the daily medical practice]. | Atrial fibrillation (AF) is a common medical problem with increasing prevalence among the elderly. Warfarin is effective in the prevention of AF-related-stroke but is often underutilized, especially in high-risk populations, like the elderly.</AbstractText>To determine, in a group of elderly patients with AF, if those ... |
13,892 | Ascending-ramp biphasic waveform has a lower defibrillation threshold and releases less troponin I than a truncated exponential biphasic waveform. | We tested the hypothesis that the shape of the shock waveform affects not only the defibrillation threshold but also the amount of cardiac damage.</AbstractText>Defibrillation thresholds were determined for 11 waveforms-3 ascending-ramp waveforms, 3 descending-ramp waveforms, 3 rectilinear first-phase biphasic waveform... |
13,893 | Recommendations regarding dietary intake and caffeine and alcohol consumption in patients with cardiac arrhythmias: what do you tell your patients to do or not to do? | The etiology of arrhythmias including atrial fibrillation is multifactorial. Most arrhythmias are associated with comorbid illnesses like hypertension, diabetes, thyroid disease, or advanced age. Although it is tempting to blame a stimulant like caffeine as a trigger for arrhythmias, the literature does not support thi... |
13,894 | Bipolar irrigated radiofrequency ablation: a therapeutic option for refractory intramural atrial and ventricular tachycardia circuits. | Irrigated radiofrequency (RF) ablation can be insufficient to eliminate intramurally located septal atrial flutter (AFL) and ventricular tachycardia (VT) circuits. Bipolar ablation between 2 ablation catheters may be considered for such circuits.</AbstractText>To evaluate the utility of bipolar irrigated ablation to te... |
13,895 | Low rate of secondary prevention ICDs in the general population: multiple-year multiple-source surveillance of sudden cardiac death in the Oregon Sudden Unexpected Death Study. | Sudden cardiac death (SCD) is a large public health problem that warrants on-going evaluation in the general population. While single-year community-based studies have been performed there is a lack of studies that have extended evaluation to multiple years in the same community.</AbstractText>From the on-going Oregon ... |
13,896 | Use of hypothermia in the intensive care unit. | Used for over 3600 years, hypothermia, or targeted temperature management (TTM), remains an ill defined medical therapy. Currently, the strongest evidence for TTM in adults are for out-of-hospital ventricular tachycardia/ventricular fibrillation cardiac arrest, intracerebral pressure control, and normothermia in the ne... |
13,897 | Wide variability in drug use in out-of-hospital cardiac arrest: a report from the resuscitation outcomes consortium. | Despite the publication and dissemination of the Advanced Cardiac Life Support guidelines, variability in the use of drugs during resuscitation from out-of-hospital cardiac arrest may exist between different Emergency Medical Services throughout North America. The purpose of this study was to characterize the use of su... |
13,898 | Stable ventricular fibrillation in a heterotopic heart transplant recipient. | We present an unusual case of ventricular fibrillation in a conscious patient symptomatic for chest pain and shortness of breath. Almost 20 years ago he underwent heterotopic cardiac transplantation for the treatment of severe idiopathic cardiomyopathy. In the precyclosporine era, this technique was extremely useful be... |
13,899 | Incidence and severity of phlebitis in patients receiving peripherally infused amiodarone. | Nurses noted that the rate of phlebitis was high when intravenous amiodarone was infused via a peripheral site. Hospital policy recommends a central vascular catheter, but this method is often not feasible because the drug is administered in emergent situations for short periods.</AbstractText>To determine the rate and... |
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