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14,000 | Intracardiac J-point elevation before the onset of polymorphic ventricular tachycardia and ventricular fibrillation in patients with an implantable cardioverter-defibrillator. | The clinical importance of the J-point elevation on electrocardiogram is controversial.</AbstractText>To study intracardiac J-point amplitude before ventricular arrhythmia.</AbstractText>Baseline 12-lead electrocardiogram and far-field right ventricular intracardiac implantable cardioverter-defibrillator electrograms w... |
14,001 | Myocardial fibrosis severity on cardiac magnetic resonance imaging predicts sustained arrhythmic events in hypertrophic cardiomyopathy. | The purpose of our study was to correlate the incidence of adequate implantable cardioverter-defibrillator (ICD) interventions in hypertrophic cardiomyopathy (HCM) patients with risk markers (RMs) for sudden cardiac death (SCD) plus myocardial fibrosis as detected by late gadolinium-enhanced cardiac magnetic resonance ... |
14,002 | Repolarization syndromes. | Repolarization syndromes, including early repolarization, Brugada, and short and long QT, have been implicated increasingly as causes of sudden cardiac death (SCD) despite no obvious mechanical cardiac abnormalities. So-called idiopathic ventricular fibrillation is now often reassigned to one of the aforementioned enti... |
14,003 | NADPH oxidases in heart failure: poachers or gamekeepers? | Oxidative stress is involved in the pathogenesis of heart failure but clinical antioxidant trials have been unsuccessful. This may be because effects of reactive oxygen species (ROS) depend upon their source, location, and concentration. Nicotinamide adenine dinucleotide phosphate oxidase (Nox) proteins generate ROS in... |
14,004 | Pregnancy outcome and management of women with an implantable cardioverter defibrillator: a single centre experience. | With improved survival of patients with congenital and inherited heart disease, there is now a younger cohort of patients with an implantable cardioverter defibrillator (ICD) for the prevention and treatment of ventricular dysrrhythmias. Young women with such disorders often wish to embark on pregnancy, but pregnancy o... |
14,005 | [Prolonged hypothermia in refractory intracranial hypertension. Report of one case]. | The use of hypothermia after cardiac arrest caused by ventricular fibrillation is a standard clinical practice, however its use for neuroprotection has been extended to other conditions. We report a 23-year-old male with intracranial hypertension secondary to a parenchymal hematoma associated to acute hydrocephalus. An... |
14,006 | Andersen-Tawil syndrome associated with aborted sudden cardiac death: atrial pacing was effective for ventricular arrhythmias. | A 37-year-old Japanese woman experienced aborted sudden cardiac death from ventricular fibrillation and was diagnosed with Andersen-Tawil syndrome by genetic analysis that revealed 2 mutations in the KCNJ2 gene. Although she received an implantation of implantable cardioverter defibrillator and beta-blocker therapy, th... |
14,007 | Renal infarction as a presentation of Austrian syndrome: thromboembolic phenomenon of pneumococcal endocarditis. | A 52-year-old unvaccinated and splenectomized man presented with fever, altered sensorium, bilateral flank pain and chest discomfort accompanied with paroxysmal atrial fibrillation with a rapid ventricular response. An abdominal computed tomography scan was performed, which revealed a right renal infarct and splenosis.... |
14,008 | Cation interdependency in acute stressor states. | Acute stressor states are inextricably linked to neurohormonal activation which includes the adrenergic nervous system. Consequent elevations in circulating epinephrine and norepinephrine unmask an interdependency that exists between K+, Mg2+ and Ca2+. Catecholamines, for example, regulate the large number of Mg2+-depe... |
14,009 | Brugada syndrome masked by ibutilide treatment in a patient with atrial flutter. | We present a case of Brugada syndrome in a young patient whose typical ECG pattern was 'masked' after ibutilide was administered for atrial flutter cardioversion. Ibutilide, a class III antiarrhythmic agent used for the treatment of atrial fibrillation and flutter, prolongs the action potential duration plateau phase b... |
14,010 | Role of imaging in ablation therapy of ventricular arrhythmias. Focus on cardiac magnetic resonance imaging. | Cardiac magnetic resonance imaging (MRI) has a central role in the management of patients with ventricular arrhythmias. Cardiac MRIs help to identify patients with risk for life-threatening arrhythmias. Delayed enhancement identifies scar tissue within the heart. Because scar harbors the arrhythmic substrate in patient... |
14,011 | Prospective risk stratification of sudden cardiac death in Marfan's syndrome. | Marfan syndrome (MFS) is a variable, autosomal-dominant disorder of the connective tissue. In MFS serious ventricular arrhythmias and sudden cardiac death (SCD) can occur. The aim of this prospective study was to reveal underlying risk factors and to prospectively investigate the association between MFS and SCD in a lo... |
14,012 | Higher incidence of atrial fibrillation in the metabolic syndrome: a Hispanic population study. | The metabolic syndrome is probably one of the main medical problems in developing countries. Purpose of this investigation was to study the metabolic syndrome at the Puerto Rico and Caribbean Cardiovascular Center with emphasis on the cardiovascular complications.</AbstractText><AbstractText Label="MATERIALS/METHODS" N... |
14,013 | Recurrent ventricular fibrillation related to hypokalemia in early repolarization syndrome. | We describe a case of early repolarization syndrome in which augmented J waves were documented during an electrical storm associated with hypokalemia. The patient was referred to our hospital for therapy to treat recurrent ventricular fibrillation (VF). The 12-lead electrocardiogram showed giant J waves associated with... |
14,014 | Persistent atrial fibrillation is associated with inability to recover atrial contractility after MAZE IV surgery in rheumatic disease. | MAZE IV surgery is effective in restoring sinus rhythm (SR) and atrial contraction (AC) in patients with nonrheumatic persistent atrial fibrillation (AF). However, there is less information on its effectiveness to restore AC in patients with rheumatic disease.</AbstractText>To assess the effectiveness of the MAZE IV su... |
14,015 | Predictors of permanent pacemaker implantation after Medtronic CoreValve bioprosthesis implantation. | High-grade conduction disturbances requiring permanent pacemaker (PPM) implantation occur in up to 40% of patients following transcatheter aortic valve implantation (TAVI). The aim of this study was to identify pre-operative risk factors for PPM implantation after TAVI with the Medtronic CoreValve prosthesis (CVP).</Ab... |
14,016 | Association of early repolarization and sudden cardiac death during an acute coronary event. | Electrocardiographic early repolarization (ER) pattern has been previously associated with arrhythmic mortality and with an increased risk of ventricular fibrillation. We hypothesized that there is an association between ER and sudden cardiac death (SCD) during an acute coronary event.</AbstractText>The present study i... |
14,017 | Electroporation induced by internal defibrillation shock with and without recovery in intact rabbit hearts. | Defibrillation shocks from implantable cardioverter defibrillators can be lifesaving but can also damage cardiac tissues via electroporation. This study characterizes the spatial distribution and extent of defibrillation shock-induced electroporation with and without a 45-min postshock period for cell membranes to reco... |
14,018 | Induction of ventricular tachycardia with the fourth extrastimulus and its relationship to risk of arrhythmic events in patients with post-myocardial infarct left ventricular dysfunction. | The prognostic significance of ventricular tachycardia (VT) induced by three extrastimuli (ES) is similar to that of VT induced by one or two ES in patients with coronary disease and abnormal left ventricular (LV) function. The significance of VT inducible with four ES is unclear. To examine the prognostic significance... |
14,019 | Decreased milk drinking causing flecainide toxicity in an older child. | Flecainide is a class IC antiarrhythmic agent, used frequently in all age groups for the treatment of tachyarrhythmias. Flecainide blocks the voltage-gated sodium channel in the myocardium, leading to prolongation of depolarisation resulting in slowed conduction velocity. Within a paediatric population, flecainide is i... |
14,020 | Effect of cardiopulmonary resuscitation on restoration of myocardial ATP in prolonged ventricular fibrillation. | There has been controversy over whether a short period of cardiopulmonary resuscitation (CPR) prior to defibrillation improves survival in patients who experienced a sudden cardiac arrest. However, there have been no reports about whether CPR restores the myocardial energy source during prolonged ventricular fibrillati... |
14,021 | Electrophysiological and hemodynamic characteristics associated with obesity in patients with atrial fibrillation. | The authors sought to characterize the left atrial (LA) and pulmonary vein (PV) electrophysiological and hemodynamic features in obese patients with atrial fibrillation (AF).</AbstractText>Obesity is associated with increased risk for AF.</AbstractText>A total of 63 consecutive patients with AF who had normal left vent... |
14,022 | Sinus rhythm versus atrial fibrillation in elderly patients with chronic heart failure--insight from the Cardiac Insufficiency Bisoprolol Study in Elderly. | It has been suggested that patients with chronic HF and atrial fibrillation (AF) may respond differently to beta-blockers than those in sinus rhythm (SR).</AbstractText>In this predefined analysis of the CIBIS-ELD trial, a total of 876 chronic HF patients (164 patients with AF) were randomized to bisoprolol or carvedil... |
14,023 | Effect of skeletal muscle Na(+) channel delivered via a cell platform on cardiac conduction and arrhythmia induction. | In depolarized myocardial infarct epicardial border zones, the cardiac sodium channel is largely inactivated, contributing to slow conduction and reentry. We have demonstrated that adenoviral delivery of the skeletal muscle Na(+) channel (SkM1) to epicardial border zones normalizes conduction and reduces induction of v... |
14,024 | Spatiotemporal behavior of high dominant frequency during paroxysmal and persistent atrial fibrillation in the human left atrium. | Sites of high dominant frequency (DF(peak)) are thought to indicate the location of drivers of atrial fibrillation (AF), but characterization of their spatiotemporal distribution and stability, critical to their relevance as targets for catheter ablation, requires simultaneous global mapping of the left atrium.</Abstra... |
14,025 | Contribution of fibrosis and the autonomic nervous system to atrial fibrillation electrograms in heart failure. | Fibrotic and autonomic remodeling in heart failure (HF) increase vulnerability to atrial fibrillation (AF). Because AF electrograms (EGMs) are thought to reflect the underlying structural substrate, we sought to (1) determine the differences in AF EGMs in normal versus HF atria and (2) assess how fibrosis and nerve-ric... |
14,026 | Holter monitoring and long-term prognosis in hypertrophic cardiomyopathy. | Limited data are available regarding Holter monitoring for cardiovascular events except for ventricular tachycardia as a risk marker for sudden death in hypertrophic cardiomyopathy (HCM). We aimed to examine Holter findings in relation to the long-term prognosis in patients with HCM.</AbstractText>Ambulatory Holter mon... |
14,027 | Implantable cardioverter-defibrillators: indications and unresolved issues. | Since the implantable cardioverter-defibrillator was first used clinically in 1980, several large randomized controlled trials have shown that therapy with this device can be beneficial in various patient populations. Evidence suggests that this therapy is useful in the secondary prevention of sudden cardiac death amon... |
14,028 | Pharmacological treatment options for hypertrophic cardiomyopathy: high time for evidence. | Hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease, affecting over one million individuals in Europe. Hypertrophic cardiomyopathy patients often require pharmacological intervention for control of symptoms, dynamic left ventricular outflow obstruction, supraventricular and ventricular arrhythmia... |
14,029 | Event synchronous adaptive filter based atrial activity estimation in single-lead atrial fibrillation electrocardiograms. | In this paper, an event synchronous adaptive filter (ESAF) is proposed to estimate atrial activity (AA) from a single-lead AF ECG in real time. The proposed ESAF is a kind of adaptive filter designed to have the reference fed with the impulse train synchronized with the R peak in a raw atrial fibrillation (AF) ECG and ... |
14,030 | The prognostic significance of right ventricular tissue Doppler parameters in patients with left ventricular systolic heart failure: an observational cohort study. | To investigate the value of tissue Doppler imaging (TDI) measurements of right ventricular (RV) systolic and diastolic function as a predictor of long term cardiovascular outcomes in patients with left ventricular (LV) systolic heart failure.</AbstractText>In patients with LV systolic heart failure, RV function has bee... |
14,031 | Atrial fibrillation, blood loss, and transfusion in patients with left ventricular dysfunction: what is the effect of cardiopulmonary bypass? | Despite advancements in surgical technique, intensive care methods and pharmaceutical prophylaxis atrial fibrillation (AF) after on-pump coronary artery bypass remains common. Transfusion, blood loss, and cardiopulmonary bypass (CPB) have been identified as risk factors for AF and adverse outcomes such as early mortali... |
14,032 | Atrial fibrillation induction by transesophageal electrophysiology studies in patients with asymptomatic ventricular preexcitation. | Ventricular preexcitation is a conduction abnormality caused by an accessory pathway bridging the atria and ventricles. If the accessory pathway conducts rapidly during atrial fibrillation (AFib), sudden death may result. The purpose of this study was to determine the ability of transesophageal electrophysiology studie... |
14,033 | Stroke and Stroke-like Episodes in Muscle Disease. | Though not obvious at a first glance, myopathies may be associated with ischemic stroke. Stroke-like episodes resemble ischemic stroke only to some extent but are a unique feature of certain mitochondrial disorders with a pathogenesis at variance from that of ischemic stroke. Only limited data are available about ische... |
14,034 | Vitamin C compromises cardiac resuscitability in a rat model of ventricular fibrillation. | Resuscitation from cardiac arrest is partly limited by progressive reduction in left ventricular distensibility, leading to decreased hemodynamic efficacy of cardiopulmonary resuscitation (CPR). Reduction in left ventricular distensibility has been linked to loss of mitochondrial bioenergetic function that can result f... |
14,035 | A case of idiopathic ventricular fibrillation in which implanted loop recorder was useful in application decision for implantation of implantable cardioverter-defibrillator. | Establishing a symptom-rhythm correlation in patients with unexplained syncope is complicated because of its sporadic, infrequent, and unpredictable nature. Recently, an implantable loop recorder (ILR) has become available to evaluate undiagnosed recurrent arrhythmic episodes particularly in unexplained syncopes, and i... |
14,036 | Torsadogenic index: a proposal to improve survival rates in cardiac arrests due to prescribed drugs. | Since unexpected sudden deaths have been reported with the use of diverse non-cardiac drugs, cardio-safety experts focused their attention on security measures to improve survival rates in heart stoppages due to this prescribed drugs (Inchauspe 2010a). Considering that prolongation of the QTc is a reliable marker of a ... |
14,037 | Brugada type 1 electrocardiogram unmasked by a febrile state following syncope. | Brugada syndrome is a genetic disease characterized by persistent or transient ST elevation in the right precordial electrocardiogram (ECG) leads with or without right bundle branch block. It represents an increased risk for sudden cardiac death despite a structurally normal heart. Brugada-type ECG can be unmasked and ... |
14,038 | A study of risk factors of stroke in patients admitted in Manipal Teaching Hospital, Pokhara. | Stroke is usually end result of predisposing conditions that originated years before the ictus. Identification of its modifiable risk factors can help in planning preventive strategies.</AbstractText>To study the risk factors of stroke in adult patients.</AbstractText>A hospital based prospective cross sectional study ... |
14,039 | Mechanical CPR devices compared to manual CPR during out-of-hospital cardiac arrest and ambulance transport: a systematic review. | The aim of this paper was to conduct a systematic review of the published literature to address the question: "In pre-hospital adult cardiac arrest (asystole, pulseless electrical activity, pulseless Ventricular Tachycardia and Ventricular Fibrillation), does the use of mechanical Cardio-Pulmonary Resuscitation (CPR) d... |
14,040 | Trends in the use of electrical cardioversion for atrial fibrillation: influence of major trials and guidelines on clinical practice. | The purpose of the present study was to assess the trends in the use of ECV following published studies that had compared rhythm and rate control strategies on atrial fibrillation (AF), and the recommendations included in the current clinical practice guidelines.</AbstractText>The REVERCAT is a population-based assessm... |
14,041 | Inhibition of intercellular coupling stabilizes spiral-wave reentry, whereas enhancement of the coupling destabilizes the reentry in favor of early termination. | Spiral-wave (SW) reentry is a major organizing principle of ventricular tachycardia/fibrillation (VT/VF). We tested a hypothesis that pharmacological modification of gap junction (GJ) conductance affects the stability of SW reentry in a two-dimensional (2D) epicardial ventricular muscle layer prepared by endocardial cr... |
14,042 | Incidence of ventricular arrhythmia and associated patient outcomes in hospitalized acute coronary syndrome patients in Saudi Arabia: findings from the registry of the Saudi Project for Assessment of Acute Coronary Syndrome (SPACE). | Mortality in acute coronary syndrome (ACS) patients with ventricular arrhythmia (VA) has been shown to be higher than those without VA. However, there is a paucity of data on VA among ACS patients in the Middle Eastern countries.</AbstractText>Prospective study of patients admitted in 17 government hospitals with ACS b... |
14,043 | Reduction in life-threatening ventricular tachyarrhythmias in statin-treated patients with nonischemic cardiomyopathy enrolled in the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy). | This study hypothesized that time-dependent statin therapy will reduce the risk of life-threatening ventricular tachyarrhythmias among patients with nonischemic cardiomyopathy (NICM) enrolled in the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy).</AbstractText>... |
14,044 | Transgenic insights linking pitx2 and atrial arrhythmias. | Pitx2 is a homeobox transcription factor involved in left-right signaling during embryogenesis. Disruption of left-right signaling in mice within its core nodal/lefty cascade, results in impaired expression of the last effector of the left-right cascade, Pitx2, leading in many cases to absence or bilateral expression o... |
14,045 | Overdrive ventricular pacing in pacemaker recipients with permanent atrial fibrillation and sleep apnea. | Cardiac pacing is ineffective in obstructive sleep apnea (SA), but it can alleviate central SA/Cheyne-Stokes respiration (CSA) in patients with heart failure (HF). We examined whether overnight overdrive ventricular pacing (OVP) has an effect on SA in pacemaker recipients with permanent atrial fibrillation (AF).</Abstr... |
14,046 | Sudden cardiac arrest due to subtotal absence of left-sided pericardium--case report and review of the literature. | Congenital absence of the pericardium is a very rare cardiac malformation, usually diagnosed fortuitously on autopsy or surgery. Symptoms related to these abnormalities are usually benign, and fatalities reported in the literature are almost exclusively secondary to herniation of the heart through a partial defect. We ... |
14,047 | [The organization and management of First Aid in the workplace: critical issues and innovations to be introduced]. | Develop an effective First Aid's system in workplaces is significantly important to the outcomes of accidents at work, thus contributing positively to create healthy and safe environments, improving responsible attitude and risk perception by workers. The italian regulation (D. Lgs. 81/08; DM 388/03) gives an important... |
14,048 | Cardiac resynchronization therapy after atrioventricular junction ablation for symptomatic atrial fibrillation: a meta-analysis. | Atrioventricular junction (AVJ) ablation with permanent pacing improves symptoms in selected patients with atrial fibrillation (AF). The optimal pacing modality after AVJ ablation remains unclear. We performed a meta-analysis of randomized controlled trials to examine whether cardiac resynchronization therapy (CRT) is ... |
14,049 | [Targeted temperature management in critical care : current 2011 recommendations]. | Since October 2011 new guidelines exist for temperature management in critical care. According to the guidelines the term targeted temperature management (TTM) should replace the term therapeutic hypothermia. There is now a strong recommendation for TTM using 32-34°C as the preferred treatment for out-of-hospital ... |
14,050 | Systematic review and meta-analysis of out-of-hospital cardiac arrest and race or ethnicity: black US populations fare worse. | Several studies have reported racial/ethnic variation in out-of-hospital cardiac arrest (OOHCA) characteristics, which engendered varying conclusions. We performed a systematic review and meta-analysed the evidence for differences in OOHCA survival when considering the patient's race and/or ethnicity.</AbstractText>We ... |
14,051 | Successful percutaneous flow redirection to the juvenile patient of fulminant myocarditis treated with percutaneous cardio-pulmonary support. | Percutaneous cardio-pulmonary support (PCPS) system is a powerful life support system for acute circulation failure. This life support system requires more than a fourteen-French cannula to the artery. Insertion with such a large tube sometimes induces damage to the peripheral circulation. We experienced the successful... |
14,052 | Cardiac disease and cognitive impairment: a systematic review. | Cognitive impairment in cardiac patients may interfere with disease management. This review describes studies examining specific cognitive impairments in cardiac patients and studies that investigate the link between echocardiographic and cognitive measures. Executive function impairments were frequently reported in di... |
14,053 | Minimally-invasive video-assisted coronary-artery bypass grafting. | In general, surgeries currently tend to be less invasive and cardiac surgery has started to follow this trend.</AbstractText>To evaluate the evolution of one hundred patients undergoing minimally-invasive coronary artery bypass grafting.</AbstractText>Access to the heart was attained through a small; 6-cm thoracotomy, ... |
14,054 | Selective site pacing from the right ventricular mid-septum. Follow-up of lead performance and procedure technique. | Pacing from the right ventricular (RV) apex is associated with adverse effects such as heart failure and atrial fibrillation. We attempted pacing from the RV mid-septum, which is theoretically a more physiological pacing site. A total of 172 consecutive patients with indications for permanent pacemaker implantation wer... |
14,055 | Incidence and time frame of life-threatening arrhythmias in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. | Life-threatening arrhythmias may complicate the hospital course of patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). The optimal duration of electrocardiographic monitoring in such patients is not well established. We aimed to determine the in... |
14,056 | Effect of oxidative stress on ventricular arrhythmia in rabbits with adriamycin-induced cardiomyopathy. | The purpose of the present study was to examine the effects of oxidative stress on ventricular arrhythmias in rabbits with adriamycin-induced cardiomyopathy and the relationship between oxidative stress and ventricular arrhythmia. Forty Japanese white rabbits were randomly divided into four groups (n=10 in each): contr... |
14,057 | TNF-α blockade improves early post-resuscitation survival and hemodynamics in a swine model of ischemic ventricular fibrillation. | Inflammatory cytokines have been implicated in the pathophysiology of post cardiac arrest syndrome, including myocardial dysfunction and hypotension, often leading to multi-organ system dysfunction and death. We hypothesized that administration of infliximab after return of spontaneous circulation (ROSC) would ameliora... |
14,058 | Assessment of exit block following pulmonary vein isolation: far-field capture masquerading as entrance without exit block. | Complete electrical isolation of pulmonary veins (PVs) remains the cornerstone of ablation therapy for atrial fibrillation. Entrance block without exit block has been reported to occur in 40% of the patients. Far-field capture (FFC) can occur during pacing from the superior PVs to assess exit block, and this may appear... |
14,059 | Shen-fu injection reduces postresuscitation myocardial dysfunction in a porcine model of cardiac arrest by modulating apoptosis. | Shen-Fu injection (SFI) following cardiac arrest exhibits cardioprotective effects, but its effect on myocardial dysfunction, a critical issue following resuscitation, is unclear. This study sought to examine whether SFI reduces postresuscitation myocardial dysfunction in a porcine model of cardiac arrest by modulating... |
14,060 | Energy status of pig donor organs after ischemia is independent of donor type. | Literature is controversial whether organs from living donors have a better graft function than brain dead (BD) and non-heart-beating donor organs. Success of transplantation has been correlated with high-energy phosphate (HEP) contents of the graft.</AbstractText>HEP contents in heart, liver, kidney, and pancreas from... |
14,061 | Common variation in the NOS1AP gene is associated with drug-induced QT prolongation and ventricular arrhythmia. | This study sought to determine whether variations in NOS1AP affect drug-induced long QT syndrome (LQTS).</AbstractText>Use of antiarrhythmic drugs is limited by the high incidence of serious adverse events including QT prolongation and torsades de pointes. NOS1AP gene variants play a role in modulating QT intervals in ... |
14,062 | [Cardiac arrest caused by coronary arterial vasospasm]. | Coronary arterial vasospasm may be associated with acute myocardial infarction, ventricular tachycardia or fibrillation as well as sudden death. Two case reports describing coronary vasospasm leading to ST-segment elevation and cardiac arrest are presented. Coronary arteriography revealed an occlusion that disappeared ... |
14,063 | Prevalence, clinical phenotype, and outcomes associated with normal B-type natriuretic peptide levels in heart failure with preserved ejection fraction. | B-type natriuretic peptide (BNP) is used widely to exclude heart failure (HF) in patients with dyspnea. However, most studies of BNP have focused on diagnosing HF with reduced ejection fraction (EF). The aim of this study was to test the hypothesis that a normal BNP level (≤100 pg/ml) is relatively common in HF ... |
14,064 | Mechanisms underlying the autonomic modulation of ventricular fibrillation initiation--tentative prophylactic properties of vagus nerve stimulation on malignant arrhythmias in heart failure. | Classical physiology teaches that vagal post-ganglionic nerves modulate the heart via acetylcholine acting at muscarinic receptors, whilst it is accepted that vagus nerve stimulation (VNS) slows heart rate, atrioventricular conduction and decreases atrial contraction; there is continued controversy as to whether the va... |
14,065 | Statins in heart failure: the paradox between large randomized clinical trials and real life. | To assess the relationship between statins and prognosis in ischemic and nonischemic patients with heart failure (HF) in a real-life cohort followed up for a long period.</AbstractText>This prospective study included 960 patients with HF with preserved or depressed left ventricular ejection fraction (LVEF), irrespectiv... |
14,066 | Induction of atrial fibrillation with adenosine during a transesophageal electrophysiology study to risk stratify a patient with asymptomatic ventricular preexcitation. | An asymptomatic adolescent male athlete was incidentally found to have ventricular preexcitation on electrocardiogram during a sports preparticipation physical. A transesophageal electrophysiology study (TEEPS) was performed after an exercise stress test failed to delineate the patient's risk of sudden cardiac death. T... |
14,067 | QT interval disturbances in elderly residents of long-term care facilities. | The QT interval reflects the total duration of ventricular myocardial repolarization. Disturbed QT--either prolonged or shortened--is associated with arrhythmia and is life-threatening.</AbstractText>To investigate an elderly population for disturbed QT interval.</AbstractText>We conducted a cross-sectional study on re... |
14,068 | A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype. | Cardiac Na(+) channels encoded by the SCN5A gene are essential for initiating heart beats and maintaining a regular heart rhythm. Mutations in these channels have recently been associated with atrial fibrillation, ventricular arrhythmias, conduction disorders, and dilated cardiomyopathy (DCM).We investigated a young ma... |
14,069 | Infusion of 4°C normal saline can improve the neurological outcome in a porcine model of cardiac arrest. | This study sought to investigate induction of therapeutic hypothermia using ice-cold intravenous fluid after cardiopulmonary resuscitation (CPR). The effects on temperature, hemodynamics, cognitive performance and the accompanying neurohistopathological changes, and apoptosis were assessed.</AbstractText>Fourteen pigle... |
14,070 | Left ventricular diastolic dysfunction in atrial fibrillation: predictors and relation with symptom severity. | Left ventricular diastolic dysfunction (LVDD) is common in the general population, but its prevalence in atrial fibrillation (AF), predictors for LVDD in AF and the association between LVDD and AF-related symptom severity has not been well studied.</AbstractText>In 124 consecutive patients (mean age 61 ± 11years, ... |
14,071 | [Brain natriuretic peptide (BNP) level predicts long term ventricular arrhythmias in patients with moderate to severe left ventricular dysfunction]. | Brain natriuretic peptide (BNP) is a powerful predictor of mortality in patients with left ventricular dysfunction. Since malignant ventricular arrhythmias such as sustained ventricular tachycardia (VT) and ventricular fibrillation (VF) are a major cause of death among those patients, we postulated that BNP levels can ... |
14,072 | [Sudden cardiac death and automated external defibrillators. Where we are in 2012?]. | Sudden cardiac death (SCD) is one of the major problems in the western world with approximately 70.000-100.000 SCD patients (pts) in Germany and 450.000 SCD victims in the US. SCD is not caused by a single factor but is a multifactorial problem. SCD is caused by ventricular tachyarrhythmias in approximately 90% of pts,... |
14,073 | Pulsatile abdominal mass is not always leaking aneurysm! | An 80-year-old male, who presented with a history of unprovoked collapse, was found to have a visible pulsation in the central upper abdomen, which disappeared on raising his arms above his shoulder ('head and shoulder' technique). There was no tenderness noted over the pulsation. He had a ventricular demand inhibited ... |
14,074 | Cardiopulmonary resuscitation and management of cardiac arrest. | The best chance of survival with a good neurological outcome after cardiac arrest is afforded by early recognition and high-quality cardiopulmonary resuscitation (CPR), early defibrillation of ventricular fibrillation (VF), and subsequent care in a specialist center. Compression-only CPR should be used by responders wh... |
14,075 | Common variation in fatty acid genes and resuscitation from sudden cardiac arrest. | Fatty acids provide energy and structural substrates for the heart and brain and may influence resuscitation from sudden cardiac arrest (SCA). We investigated whether genetic variation in fatty acid metabolism pathways was associated with SCA survival.</AbstractText>Subjects (mean age, 67 years; 80% male, white) were o... |
14,076 | Efficacy of landiolol hydrochloride for atrial fibrillation after open heart surgery. | It is important to establish effective treatment for postoperative atrial fibrillation (AF), the most common complication after cardiac surgery. We evaluated the efficacy and safety of landiolol hydrochloride for rhythm conversion in patients with postoperative AF. Among 134 patients who developed new-onset AF after op... |
14,077 | Clinical characteristics and prevalence of early repolarization associated with ventricular arrhythmias following acute ST-elevation myocardial infarction. | Early repolarization (ER) on a 12-lead electrocardiogram has recently been associated with ventricular tachyarrhythmias (VTAs) in patients without structural heart disease and in patients with healed myocardial infarction (MI). An association between ER and VTAs in the setting of acute ST-segment elevation MI (STEMI) h... |
14,078 | Factors influencing left atrial volume in treated hypertension. | Left atrial (LA) enlargement has been documented to occur in hypertension (HT), and has been an index for evaluating the diastolic function of the left ventricle. Enlargement of the LA is one of the vital factors that induce heart failure and atrial fibrillation (AF) in patients with HT.</AbstractText>130 treated hyper... |
14,079 | Transcatheter versus surgical treatment for aortic stenosis: patient selection and early outcome. | To describe short-term clinical and echocardiography outcomes in patients undergoing transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR). To explore patient selection criteria for treatment with TAVI.</AbstractText>TAVI patients (n = 45) were matched to SAVR patients (n =&... |
14,080 | Amplitude Changes during Ventricular Fibrillation: A Mechanistic Insight. | Clinically in ventricular fibrillation (VF), ECG amplitude, and frequency decrease as ischemia progresses and predict defibrillation success. In vitro ECG amplitude declines without ischemia, independent of VF frequencies. This study examines the contribution of cellular electrical activity and global organization to E... |
14,081 | Same-day discharge after catheter ablation for routine arrhythmias: an initial experience. | Same-day discharge (SDD) in the setting of catheter ablation (CA) is not widely applied. We present our experience concerning SDD in a selected population of patients who underwent CA; the outcome was evaluated in terms of feasibility and safety.</AbstractText>401 CA procedures were performed at our institution between... |
14,082 | A strategy to achieve CRT response in permanent atrial fibrillation without obligatory atrioventricular node ablation. | Cardiac resynchronization therapy (CRT) is an established method in patients with severe heart failure and wide QRS configuration, particularly during sinus rhythm (SR). In CRT patients with permanent atrial fibrillation (AF), there is no general consensus regarding the need for atrioventricular node (AVN) ablation. Th... |
14,083 | Atrial Fibrillation and Brugada Syndrome. | Since its first description in 1992, the Brugada syndrome (BrS) has attracted significant attention from the cardiology community because of its association with malignant ventricular arrhythmias and sudden cardiac death. Supraventricular tachyarrhythmias in BrS represent a unique and seemingly higher-risk clinical sub... |
14,084 | A Patient with a 40% Ejection Fraction Undergoes Atrioventricular Nodal Ablation for the Management of Atrial Fibrillation with Rapid Ventricular Rates. What Type of Device Should He Receive? | Patients with symptomatic atrial fibrillation not amenable to pharmacologic therapy or catheter ablation may be appropriate candidates for atrioventricular nodal (AVN) ablation and placement of a permanent pacemaker. The question arises as to whether to implant a right ventricular (RV)-only pacing device or a cardiac r... |
14,085 | Initial clinical predictors of significant coronary lesions after resuscitation from cardiac arrest. | Urgent coronary angiography following cardiac arrest is an important consideration as part of a therapeutic hypothermia/postresuscitation care bundle. Few data exist to guide the selection of patients who should receive postarrest angiography. This investigation sought to evaluate patient-level variables on initial pos... |
14,086 | Serum uric acid levels are associated with atrial fibrillation in patients with ischemic heart failure. | We evaluated the association between serum uric acid (SUA) and atrial fibrillation (AF) in patients with chronic heart failure (HF). Totally, 363 patients with chronic HF were included in the study. Of all, 78 patients had AF and 285 patients were in normal sinus rhythm. Serum uric acid was significantly increased in p... |
14,087 | Sustained ventricular tachycardia and ventricular fibrillation complicating non-ST-segment-elevation acute coronary syndromes. | Ventricular arrhythmias remain a lethal complication of acute coronary syndromes (ACS). However, the incidence and prognosis of sustained ventricular tachycardia/ventricular fibrillation (VT/VF) in contemporary non-ST-segment-elevation (NSTE) ACS populations are not well described.</AbstractText>We examined the inciden... |
14,088 | The use of ω-3 poly-unsaturated fatty acids in heart failure: a preferential role in patients with diabetes. | To review the evidence for a beneficial effect of ω-3 PUFAs in heart failure (HF) and its co-morbidities, their possible preferential effect in diabetes and the potential mechanism for their benefit.</AbstractText>We summarize the clinical studies which investigated the use of ω-3 PUFAs in patients with HF ... |
14,089 | The use of left ventricular assist devices in the treatment of class IV heart failure patients: what the non-heart failure specialist needs to know. | The New York Heart Association class IV heart failure patient represents a very sick patient population with a poor 6-month survival rate. With appropriate selection and timing, left ventricular assist devices can provide improved outcomes while these patients are supported for bridge to heart transplant or destination... |
14,090 | The relationship of asymptomatic intracranial artery stenosis and Framingham stroke risk profile in a Northern Chinese industrial city. | Intracranial artery stenosis may be the most frequent cause of ischemic stroke in the world. Early detection of asymptomatic intracranial artery stenosis may allow for therapeutic intervention. Most elements of the Framingham stroke risk profile (FSRP) are also risk factors for intracranial artery stenosis. Thus, the F... |
14,091 | From a wide to a narrow QRS tachycardia and back. What is the mechanism? | A 40-year-old man developed a near syncope during exercise due to a wide complex tachycardia with periods of changing RR intervals accompanied by changes in QRS morphology. The differential diagnosis of this electrocardiographic pattern is discussed. |
14,092 | Extra- and intracellular recordings from the avjunction: discerning the mechanisms for irregular ventricular responses during supraventricular arrhythmias. | There has been a long-standing controversy regarding the mechanism(s) to explain the irregular ventricular response during atrial tachycardia (AT) or atrial fibrillation (AF) and where the site of block, if any, resides in the atrioventricular (AV) junction.</AbstractText>We studied 12 Langendorff preparations perfused... |
14,093 | The occurrence of atrial fibrillation in former top-level handball players above the age of 50. | Cardiac adaptation to sports activity in endurance athletes is considerably different from that in power athletes. The effects of a high-level team sport like handball, one of the most popular sports in the world, performed at a younger age, on cardiac rhythm in individuals above the age of 50 have not been investigate... |
14,094 | Optimal ablation strategies for different types of ventricular tachycardias. | Ablation strategies for almost all types of ventricular tachycardias have now been established. The optimal ablation strategy for ventricular tachycardia is determined by the site of origin and the electrophysiological mechanisms. Electrocardiograms, an understanding of the common sites of basic disease, and identifica... |
14,095 | A validated prediction tool for initial survivors of in-hospital cardiac arrest. | Accurate estimation of favorable neurological survival after in-hospital cardiac arrest could provide critical information for physicians, patients, and families.</AbstractText>Within the Get With the Guidelines-Resuscitation registry, we identified 42,957 patients from 551 hospitals admitted between January 2000 and O... |
14,096 | Interventricular heterogeneity as a substrate for arrhythmogenesis of decoupled mitochondria during ischemia in the whole heart. | Myocardial ischemia results in metabolic changes, which collapse the mitochondrial network, that increase the vulnerability of the heart to ventricular fibrillation (VF). It has been demonstrated at the single cell level that uncoupling the mitochondria using carbonyl cyanide p-(tri-fluoromethoxy)phenyl-hydrazone (FCCP... |
14,097 | Renin-angiotensin system inhibitors can suppress atrial fibrillation recurrence after encircling ipsilateral pulmonary vein isolation in patients with a non-dilated left atrium. | The purpose of this study was to investigate whether the effects of renin-angiotensin system inhibitors (RASIs) after encircling ipsilateral pulmonary veins isolation (EIPVsI) for atrial fibrillation (AF) differed between patients with non-dilated and dilated left atria.</AbstractText>We retrospectively studied 292 con... |
14,098 | Prognostic significance of reciprocal ST-segment depression in patients with acute STEMI undergoing immediate invasive intervention. | Reciprocal changes are frequent in patients with acute ST-segment elevation myocardial infarction (STEMI). However, their prognostic significance is not clear in patients undergoing immediate invasive intervention.</AbstractText>We retrospectively examined 165 consecutive patients with STEMI receiving immediate invasiv... |
14,099 | Cardiac arrest with refractory ventricular fibrillation: a successful resuscitation using extracorporeal membrane oxygenation. | Extracorporeal membrane oxygenation (ECMO) is a form of a mechanical cardiopulmonary life-support system and an adjunct to prolonged cardiac resuscitation. The ECMO results in good outcomes for patients with in-hospital cardiac arrest. We present a case of a 52-year-old man with out-of-hospital cardiac arrest caused by... |
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