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14,200 | High incidence of cardiovascular complications in pheochromocytoma. | Excess of catecholamines in pheochromocytoma is usually accompanied with classical symptoms and signs. In some cases, severe cardiovascular complications (e. g., heart failure, myocardial infarction) may occur. We performed a retrospective analysis focused on the incidence of cardiovascular complications (classified as... |
14,201 | Clinical pharmacokinetics and therapeutic efficacy of esmolol. | Esmolol is a unique cardioselective β(1)-receptor blocking agent with a rapid onset and short duration of action. Since our previous review in 1995, the pharmacokinetics and efficacy of esmolol have been investigated in a number of acute care settings. Three studies investigated the pharmacokinetics and safety of... |
14,202 | Neuroprotection and hypothermia in infants and children. | Brain injury is the leading cause of death in pediatric ICU. Current evidence supports the use of therapeutic hypothermia (TH) in unconscious patients after out-of-hospital cardiac arrest when the initial heart rhythm was ventricular fibrillation. TH has been proved to be also beneficial in term neonates after hypoxic-... |
14,203 | Left ventricular posterior wall thickness is an independent risk factor for paroxysmal atrial fibrillation. | Atrial fibrillation is the most common significant cardiac arrhythmia in clinical practice, but its risk factors remain to be clarified. We have hypothesized that left ventricular posterior wall thickness is an independent risk factor for paroxysmal atrial fibrillation (PAF).</AbstractText>A total of 166 consecutive pa... |
14,204 | Automatic assessment of atrial pacing threshold in current medical practice. | The aim of this study was to validate the ambulatory automatic atrial threshold monitoring algorithm by comparing the measurements assessed by the automatic system and those evaluated manually by the physician at discharge, 2- and 8-month follow-up sessions.</AbstractText>This is an observational multicentric prospecti... |
14,205 | Catheter ablation utilizing remote magnetic navigation: a review of applications and outcomes. | The utilization of the NIOBE™ magnetic navigation system (MNS, Stereotaxis, St. Louis, MO, USA) has increased significantly since the first published report in 2002. There has been much enthusiasm for this technology as a means to reduce radiation exposure to the patient and physician alike, and potentially decr... |
14,206 | Impact of right ventricular apical pacing and its frequency on left atrial function. | Right ventricular apical (RVA) pacing induces left ventricular (LV) dyssynchrony, increases the risk of persistent atrial fibrillation in the long term. The aim was to investigate the effects of RVA pacing on left atrial (LA) function, which are unknown.</AbstractText>Echocardiographic evaluation including LV dyssynchr... |
14,207 | Discriminating clinical features of heart failure with preserved vs. reduced ejection fraction in the community. | Heart failure (HF) is a major public health burden worldwide. Of patients presenting with HF, 30-55% have a preserved ejection fraction (HFPEF) rather than a reduced ejection fraction (HFREF). Our objective was to examine discriminating clinical features in new-onset HFPEF vs. HFREF.</AbstractText>Of 712 participants i... |
14,208 | Phosphodiesterase inhibitors, congestive heart failure, and sudden death: time for re-evaluation. | A 42-year-old diabetic man was admitted with systolic heart failure and pulmonary hypertension being treated with sildenafil for the previous year. With an increase in creatinine, he experienced 3 episodes of ventricular tachycardia and ventricular fibrillation. Withdrawal of the phosphodiesterase (PDE) inhibitor resul... |
14,209 | Relationship between plasma concentrations of N-terminal pro brain natriuretic peptide and the characteristics and outcome of patients with a clinical diagnosis of diastolic heart failure: a report from the PEP-CHF study. | The aim of this study was to explore the relationships between plasma concentrations of N-terminal pro brain natriuretic peptide (NT-proBNP) and characteristics and prognosis of patients with heart failure and preserved (HFPEF) left ventricular ejection fraction (LVEF). No substantial trial has shown that treatment alt... |
14,210 | Syncope in Brugada syndrome patients: prevalence, characteristics, and outcome. | The report from the 2nd Consensus Committee on BrS suggests that all patients with syncope without a "clear extracardiac cause" should have an implantable cardioverter-defibrillator (ICD). However, a clear extracardiac cause for syncope may be difficult to prove.</AbstractText>The purpose of this study was to character... |
14,211 | Enhancing Cardiac Resynchronization Therapy for Patients with Atrial Fibrillation: The Role of AV Node Ablation. | Cardiac resynchronization therapy (CRT) has evolved as an effective therapy for patients with congestive heart failure (CHF) and ventricular dyssynchrony, currently defined as a wide QRS on the electrocardiogram. While multiple randomized controlled trials have confirmed the favorable effects of CRT on mortality and he... |
14,212 | Modifications of mechanoelectric feedback induced by 2,3-butanedione monoxime and Blebbistatin in Langendorff-perfused rabbit hearts. | Myocardial stretching is an arrhythmogenic factor. Optical techniques and mechanical uncouplers are used to study the mechanoelectric feedback. The aim of this study is to determine whether the mechanical uncouplers 2,3-butanedione monoxime and Blebbistatin hinder or modify the electrophysiological effects of acute mec... |
14,213 | Prolongation of QTc and risk of stroke: The REGARDS (REasons for Geographic and Racial Differences in Stroke) study. | The purpose of this study was to examine the association between prolongation of QT interval corrected for heart rate (QTc) with incident stroke.</AbstractText>Unlike cardiovascular morbidity and mortality, little is known about the relationship between QTc and risk of stroke.</AbstractText>A total of 27,411 participan... |
14,214 | Advances in catheter ablation: a burning trail! | The last 15 years have literally witnessed a revaluation in the management of patients with cardiac arrhythmia. Although the visibility for these advances has come from successful catheter ablation of common arrhythmia, these advances could not have occurred without the preceding details where in painstaking anatomic a... |
14,215 | Safety of pulmonary vein isolation and left atrial complex fractionated atrial electrograms ablation for atrial fibrillation with phased radiofrequency energy and multi-electrode catheters. | Recently, a multi-electrode catheter system using phased radiofrequency (RF) energy was developed specifically for atrial fibrillation (AF) ablation: the pulmonary vein ablation catheter (PVAC), the multi-array septal catheter (MASC), and the multi-array ablation catheter (MAAC). Initial results of small trials have be... |
14,216 | An approach to echocardiography in hypertrophic cardiomyopathy and other causes of LVH. | Hypertrophic cardiomyopathy (HCM) is the most prevalent genetic cardiovascular disease with a prevalence of 1:500 in the general population. Its identification is of critical importance as it is a common cause of sudden death in the young and can lead to considerable morbidity, including heart failure and atrial fibril... |
14,217 | Blood pressure and other determinants of new-onset atrial fibrillation in patients at high cardiovascular risk in the Ongoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial/Telmisartan Randomized AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease studies. | Evidence on new-onset atrial fibrillation in high-risk vascular patients without heart failure is limited. New-onset atrial fibrillation was a prespecified secondary objective of the Ongoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial (ONTARGET)/Telmisartan Randomized AssessmeNt Study in AC... |
14,218 | Thoracoscopic epicardial ablation of the left and right atrium. Beating heart procedure in patients with atrial fibrillation. | Atrial fibrillation (AF) is a common arrhythmia affecting approximately 1% to 2% of the general population.</AbstractText>The aim of the study was to evaluate the efficacy and safety of thoracoscopic ablation in patients with AF.</AbstractText>A total of 25 patients aged from 42 to 77 years (mean 56.4 years) with persi... |
14,219 | Electrical storm in short-QT syndrome successfully treated with Isoproterenol. | Short-QT Syndrome. A 28-year-old man was admitted after aborted sudden cardiac death while sleeping. QTc was 320 ms, suggesting short-QT syndrome (SQTS). The patient then presented with electrical storm with 8 successive episodes of ventricular fibrillation while on deep sedation and hypothermia. Isoproterenol infusion... |
14,220 | Cardiac denervation procedure to treat refractory angina in a patient with Churg-Strauss syndrome and non-obstructive coronary lesions. | Cardiac involvement in Churg-Strauss syndrome is common and represents the main cause of mortality. We report the case of a patient with Churg-Strauss vasculitis, mitral regurgitation with left ventricular dysfunction, paroxysmal atrial fibrillation and refractory angina with non-significant coronary lesions. Cardiac d... |
14,221 | A focus on antiarrhythmic properties of ranolazine. | Ranolazine is an antianginal drug that inhibits a number of ion currents that are important for the genesis of transmembrane cardiac action potential. It was initially developed as an antianginal agent but was found to additionally exert antiarrhythmic actions, due to its multichannel-blocking properties. In recent yea... |
14,222 | Elimination of local abnormal ventricular activities: a new end point for substrate modification in patients with scar-related ventricular tachycardia. | Catheter ablation of ventricular tachycardia (VT) is effective and particularly useful in patients with frequent defibrillator interventions. Various substrate modification techniques have been described for unmappable or hemodynamically intolerable VT. Noninducibility is the most frequently used end point but is assoc... |
14,223 | Transient ST-segment elevation after transseptal puncture for atrial fibrillation ablation in two cases. | The present report demonstrates two cases of transient inferior ST-segment elevation accompanied by profound hypotension and bradycardia immediately after transseptal puncture for catheter ablation of atrial fibrillation. This rare complication of transseptal puncture was resolved quickly within several minutes. The mo... |
14,224 | Ventricular fibrillation hampers the restoration of creatine-phosphate levels during simulated cardiopulmonary resuscitations. | Recurrences of ventricular fibrillation (VF) during cardiopulmonary resuscitation (CPR) are associated with a reduced chance of survival. The effect of VF during CPR on the myocardium is unknown. We tested the hypothesis that VF during simulated CPR reduces the restoration of the myocardial energy state and contractile... |
14,225 | Prevalence of atrial fibrillation in the general population and in high-risk groups: the ECHOES study. | To establish the prevalence of atrial fibrillation (AF) in the general population in the UK, and in those with risk factors.</AbstractText>The prevalence of AF on electrocardiography was established in prospectively selected groups: 3960 randomly selected from the population, aged 45+; 782 with a previous diagnosis of ... |
14,226 | Electrical defibrillation outcome prediction by waveform analysis of ventricular fibrillation in cardiac arrest out of hospital patients. | Indexes such as amplitude spectrum area (AMSA) and power spectrum area (PSA) obtained from electrocardiogram waveform analysis are possible predictors of outcome after electrical defibrillation for ventricular fibrillation (VF). In this study, we examined AMSA and PSA to determine whether these parameters can predict d... |
14,227 | Improved cerebral perfusion pressures and 24-hr neurological survival in a porcine model of cardiac arrest with active compression-decompression cardiopulmonary resuscitation and augmentation of negative intrathoracic pressure. | Generation of negative intrathoracic pressure during the decompression phase of cardiopulmonary resuscitation enhances the refilling of the heart. We tested the hypothesis that when compared with closed-chest manual compressions at 80 chest compressions per min, treatment with active compression-decompression cardiopul... |
14,228 | [Sudden death caused by a less lethal weapon chest-wall injury (Commotio cordis)]. | Less lethal weapons, like Flashball, are more and more used since 1995 in law enforcement, even by the local police to neutralize combative individuals and to disperse riot crowds. This gun fires large rubber bullets and has been incriminated many times in cases of face injuries with functional consequences. In this ca... |
14,229 | Documentation of impaired coronary blood flow by TIMI frame count method in patients with atrial fibrillation. | Atrial fibrillation (AF) is associated with impaired coronary flow and diminished myocardial perfusion. In the present study we aimed to evaluate coronary blood flow by means of Thrombolysis in Myocardial Infarction (TIMI) frame count (TFC) in patients with AF in the absence of obstructive coronary artery disease (CAD)... |
14,230 | A mechanical characterization of the porcine atria at the healthy stage and after ventricular tachypacing. | Atrial fibrillation (AF) is a cardiac arrhythmia that highly increases the risk of stroke and is associated with significant but still unexplored changes in the mechanical behavior of the tissue. Planar biaxial tests were performed on tissue specimens from pigs at the healthy stage and after ventricular tachypacing (VT... |
14,231 | Cardiovascular disease in women: implications for improving health outcomes. | To collate data on women and cardiovascular disease in Australia and globally to inform public health campaigns and health care interventions.</AbstractText>Literature review.</AbstractText>Women with acute coronary syndromes show consistently poorer outcomes than men, independent of comorbidity and management, despite... |
14,232 | Impact of early intravenous epinephrine administration on outcomes following out-of-hospital cardiac arrest. | The effectiveness of epinephrine administration for cardiac arrests has been shown in animal models, but the clinical effect is still controversial.</AbstractText>A prospective, population-based, observational study in Osaka involved consecutive out-of-hospital cardiac arrest (OHCA) patients from January 2007 through D... |
14,233 | Importance of ventricular tachycardia storms not terminated by implantable cardioverter defibrillators shocks in patients with CASQ2 associated catecholaminergic polymorphic ventricular tachycardia. | In this study, the clinical and implantable cardioverter-defibrillator (ICD)-related follow-up of patients with catecholaminergic polymorphic ventricular tachycardia (CPVT) with homogenous missense mutations in CASQ2 was summarized. Patients were followed in a pediatric cardiology clinic and an ICD clinic. All patients... |
14,234 | Atrial fibrillation management, outcomes and predictors of stable disease in daily practice: prospective non-interventional study. | We aimed to describe the current management of patients with atrial fibrillation (AF) by cardiologists, and to identify predicting factors for a stable disease course.</AbstractText>2753 consecutive patients with ECG-confirmed AF in the previous 12 months were documented in a 1-year observational (non-interventional) s... |
14,235 | Early surgery for asymptomatic mitral regurgitation: importance of atrial fibrillation. | It remains controversial whether early mitral valve (MV) repair should be performed for severe degenerative mitral regurgitation (MR) without symptoms, left ventricular (LV) dilatation or dysfunction, atrial fibrillation (AF) or pulmonary artery hypertension (PH), even at experienced surgical centers. The study aim was... |
14,236 | Impact of changes in resuscitation practice on survival and neurological outcome after out-of-hospital cardiac arrest resulting from nonshockable arrhythmias. | Out-of-hospital cardiac arrest (OHCA) claims millions of lives worldwide each year. OHCA survival from shockable arrhythmias (ventricular fibrillation/ tachycardia) improved in several communities after implementation of American Heart Association resuscitation guidelines that eliminated "stacked" shocks and emphasized... |
14,237 | Tissue Doppler imaging-derived myocardial acceleration during isovolumetric contraction predicts pulmonary capillary wedge pressure in patients with reduced ejection fraction. | Tissue Doppler imaging-obtained isovolumetric myocardial acceleration (IVA) is load independent, reportedly predicts systolic functions, and correlates with exercise capacity in patients with reduced ejection fraction (EF). We hypothesized that IVA correlates with the pulmonary capillary wedge pressure (PCWP) in patien... |
14,238 | Unrepaired tetralogy of fallot in an 85-year-old man. | Tetralogy of Fallot is the most common cyanotic congenital heart defect and accounts for about 5% of all congenital cardiopathies. The definitive treatment modality for tetralogy of Fallot is reparative surgery, which is recommended to be performed by the time of diagnosis. Without surgical repair, most patients would ... |
14,239 | Effect of dietary omega-3 polyunsaturated Fatty acids on heart rate and heart rate variability in animals susceptible or resistant to ventricular fibrillation. | The consumption of omega-3 polyunsaturated fatty acids (n-3 PUFAs) has been reported to reduce cardiac mortality following myocardial infarction as well as to decrease resting heart rate (HR) and increase HR variability (HRV). However, it has not been established whether n-3 PUFAs exhibit the same actions on HR and HRV... |
14,240 | Spontaneous coronary artery dissection in a young woman without risk factors. | Spontaneous coronary artery dissection is a very rare event and is more common in women than in men. Pregnancy and the early puerperium stage have been recognized as predisposing factors for this condition.</AbstractText>A 33-year-old woman presented to the Emergency Department (ED) with chest pain; the patient's elect... |
14,241 | Pulmonary vein isolation for the treatment of drug-refractory atrial fibrillation in adults with congenital heart disease. | Atrial fibrillation (AF) is a common arrhythmia in adults with congenital heart disease (CHD). Long-term antiarrhythmic therapy (AAT) in these patients has significant shortcomings. The safety and efficacy of pulmonary vein antrum isolation (PVAI) for the treatment of AF in CHD is presently unknown.</AbstractText>We hy... |
14,242 | Degenerating regenerating torsades de pointes. | Ventricular fibrillation (VF) commonly ends in death. Isolated case reports describe the uncommon occurrence of spontaneous termination of VF. Torsades de pointes (TdP), a peculiar form of polymorphic ventricular tachycardia associated with a prolonged QT interval on the surface electrocardiogram, most often spontaneou... |
14,243 | Enhanced sensitivity of aged fibrotic hearts to angiotensin II- and hypokalemia-induced early afterdepolarization-mediated ventricular arrhythmias. | Unlike young hearts, aged hearts are highly susceptible to early afterdepolarization (EAD)-mediated ventricular fibrillation (VF). This differential may result from age-related structural remodeling (fibrosis) or electrical remodeling of ventricular myocytes or both. We used optical mapping and microelectrode recording... |
14,244 | Contractile parameters and occurrence of alternans in isolated rat myocardium at supra-physiological stimulation frequency. | The cardiac refractory period prevents the heart from tetanic activation that is typically used in noncardiac striated muscle tissue. To what extent the refractory period prevents successive action potentials to activate the excitation-contraction coupling process and contractile machinery at supra-physiological rates,... |
14,245 | Role of KATP channel in electrical depression and asystole during long-duration ventricular fibrillation in ex vivo canine heart.<Pagination><StartPage>H2396</StartPage><EndPage>H2409</EndPage><MedlinePgn>H2396-409</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1152/ajpheart.00752.2011</ELocationID>... | Long-duration ventricular fibrillation (LDVF) in the globally ischemic heart is characterized by transmurally heterogeneous decline in ventricular fibrillation rate (VFR), emergence of inexcitable regions, and eventual global asystole. Rapid loss of both local and global excitability is detrimental to successful defibr... |
14,246 | Impairment of carotid artery blood flow by supraglottic airway use in a swine model of cardiac arrest. | Supraglottic airway devices (SGDs) are often used as an alternative to endotracheal tube (ETT) during cardiopulmonary resuscitation (CPR). SGDs can be inserted 'blindly' and rapidly, without stopping compressions. These devices utilize pressurized balloons to direct air to the trachea and prevent esophagus insufflation... |
14,247 | Breathing during cardiac arrest following exercise: a new function of the respiratory system? | We have found in four sheep that, following a muscular exercise, minute ventilation is maintained for 34-131 s during a cardiac arrest (CA), at a magnitude (from 28.2 and 54.7 l min(-1)) similar to the level of ventilation (and thus proportional to the metabolic rate) preceding the period of asystole. Breathing was mai... |
14,248 | Sympathetic innervation of the anterior left ventricular wall by the right and left stellate ganglia. | The sympathetic nervous system is thought to play a role in the genesis of ventricular tachyarrhythmias (VT). Left and added right cardiac sympathectomy have been shown to reduce the burden of arrhythmias in the setting of a VT storm. However, the contribution of the right stellate ganglion (RSG) and the left stellate ... |
14,249 | Fate of patients with prehospital resuscitation for ST-elevation myocardial infarction and a high rate of early reperfusion therapy (results from the PREMIR [Prehospital Myocardial Infarction Registry]). | Patients with acute ST-segment elevation myocardial infarction (STEMI) needing prehospital cardiopulmonary resuscitation (CPR) have a very high adverse-event rate. However, little is known about the fate of these patients and predictors of mortality in the era of early reperfusion therapy. From March 2003 through Decem... |
14,250 | LR-PED rule: low risk pulmonary embolism decision rule - a new decision score for low risk pulmonary embolism. | When accurately diagnosed, non-massive Pulmonary embolism (PE) has a low mortality rate. However, some patients initially considered to be low risk show progressive deterioration. This research aims at developing a preliminary score that allows detection of low risk patients potentially eligible for outpatient treatmen... |
14,251 | Anticoagulation therapy in patients with heart failure due to systolic dysfunction and sinus rhythm: analysis of REDINSCOR registry. | In patients with heart failure, left ventricular ejection fraction ≤35% and sinus rhythm without conditions such as atrial fibrillation, thrombus or history of thromboembolic events, the use of anticoagulation is controversial. Our objective was to evaluate the anticoagulation strategy in these patients, variabl... |
14,252 | Nonlinearity between action potential alternans and restitution, which both predict ventricular arrhythmic properties in Scn5a+/- and wild-type murine hearts. | Electrocardiographic QT- and T-wave alternans, presaging ventricular arrhythmia, reflects compromised adaptation of action potential (AP) duration (APD) to altered heart rate, classically attributed to incomplete Na(v)1.5 channel recovery prior to subsequent stimulation. The restitution hypothesis suggests a function w... |
14,253 | Paradoxical atrial undersensing by a dual chamber pacemaker during atrial fibrillation. | This report describes paradoxical atrial undersensing by a dual chamber pacemaker in a patient with paroxysmal atrial fibrillation. Atrial undersensing was present only when the device was programmed to a high sensitivity but sensing normalized when a lower sensitivity was programmed. This unusual response should be di... |
14,254 | Late diagnosis of congenital cardiovascular defect. | Coarctation of the aorta (CoA) is a common congenital anomaly that is usually treated in infancy or childhood. Adult patients with coarctation have a high incidence of associated cardiac disorders, including valve diseases, atrial fibrillation and ischemic heart disease. Most patients with uncorrected CoA die before re... |
14,255 | Left ventricular assist device implantation in a patient who had previously undergone apical myectomy for hypertrophic cardiomyopathy. | Apical hypertrophy is a rare variant of hypertropic cardiomyopathy. These patients may present with end-stage congestive heart failure subsequent to long standing diastolic dysfunction. We report the technique for left ventricular assist device insertion in a patient with previous apical myectomy for hypertrophic cardi... |
14,256 | Why and how to support screening strategies to prevent sudden death in athletes. | Sudden death in athletes occurs because of the existence of hidden cardiovascular disorders which, during effort, may jeopardize the electrical stability of the heart, triggering ventricular tachycardia and/or fibrillation. Apart from rare conditions of ion channel diseases in the setting of a structurally normal heart... |
14,257 | Tricuspid regurgitation after successful mitral valve surgery. | The tricuspid valve (TV) is inseparably connected with the mitral valve (MV) in terms of function. Any pathophysiological condition concerning the MV is potentially a threat for the normal function of the TV as well. One of the most challenging cases is functional tricuspid regurgitation (TR) after surgical MV correcti... |
14,258 | Unmasking of myopotential oversensing by an integrated bipolar defibrillator lead following AV node ablation. | A 73-year-old man with nonischemic cardiomyopathy underwent catheter ablation of ventricular tachycardia that had resulted in frequent shocks from his implanted cardiac resynchronization therapy defibrillator (CRT-D). Coexisting atrial fibrillation required AV node ablation which rendered the patient pacemaker dependen... |
14,259 | Genetic suppression of Gαs protein provides rate control in atrial fibrillation. | Gene therapy-based modulation of atrioventricular (AV) conduction by overexpression of a constitutively active inhibitory Gα(i) protein effectively reduced heart rates in atrial fibrillation (AF). However, catecholamine stimulation caused an excessive increase in ventricular rate. We hypothesized that modest gene... |
14,260 | Novel mutations in the KCND3-encoded Kv4.3 K+ channel associated with autopsy-negative sudden unexplained death. | Heritable arrhythmia syndromes, including Brugada syndrome (BrS) and idiopathic ventricular fibrillation (IVF), may serve as the pathogenic basis for autopsy-negative sudden unexplained death (SUD) and sudden infant death syndrome (SIDS). Emerging evidence has linked perturbations in the transient outward current (I(to... |
14,261 | [Commentary on the 2010 ESC guidelines on device therapy in heart failure ]. | As part of the 2010 focused update of ESC guidelines on device therapy in heart failure, the guidelines on pacemakers in the treatment of heart failure were renewed. A new feature is that cardiac resynchronization therapy (CRT) is indicated for New York Heart Association (NYHA) class III and IV irrespective of the pres... |
14,262 | Long-term outcomes of mechanical valve replacement in patients with atrial fibrillation: impact of the maze procedure. | The long-term benefits of the maze procedure in patients with chronic atrial fibrillation undergoing mechanical valve replacement who already require lifelong anticoagulation remain unclear.</AbstractText>We evaluated adverse outcomes (death; thromboembolic events; composite of death, heart failure, or valve-related co... |
14,263 | The ratio of observed to predicted left ventricular mass is independently associated with increased cardiovascular events in patients with chronic kidney disease. | A condition involving the growth of the myocardium that exceeds hemodynamic needs has been reported and called as inappropriate left ventricular mass (LVM). The appropriateness of LVM can be estimated by the ratio of observed LVM to predicted LVM. The excessive growth of LVM is frequently noted in patients with chronic... |
14,264 | [The influence of heartbeat acceptance window settings on left ventricular function and perfusion parameters]. | To evaluate the influence of heartbeat acceptance window settings on left ventricular function and perfusion parameters of the arrhythmia patients during gated myocardial perfusion imaging.</AbstractText>Twenty eight fibrillation patients were consecutively recruited to undergo myocardial perfusion SPECT. The Concurren... |
14,265 | Atrial flutter in normal heart could be first manifestation of Brugada syndrome. | Brugada syndrome is one of the important causes of sudden cardiac death in young adults. The condition is associated with typical ECG changes in anteroseptal leads V1 and V2 that can be unmasked by various medications, electrolyte disturbances, and even by fever in susceptible individuals. We here report the case of a ... |
14,266 | Dialysis-dependent changes in ventricular repolarization. | Epidemiological data suggest increased risk of sudden death during and immediately after hemodialysis. Microvolt T-wave alternans (mTWA) is an electrocardiogram (ECG) measure of abnormal ventricular repolarization, which can be used in sudden death risk stratification. The aim of this study was to determine whether mTW... |
14,267 | A randomized study of defibrillator lead implantations in the right ventricular mid-septum versus the apex: the SEPTAL study. | The study was designed to evaluate the feasibility and performance of right ventricular (RV) mid-septal versus apical implantable defibrillator (ICD) lead placement.</AbstractText>SEPTAL is a randomized, noninferiority trial, which randomly assigned patients to implantation of ICD leads in the RV mid-septum versus apex... |
14,268 | Adverse effects of long-term right ventricular apical pacing and identification of patients at risk of atrial fibrillation and heart failure. | In patients needing a pacemaker (PM) for bradycardia indications, the amount of right ventricular (RV) apical pacing has been correlated with atrial fibrillation (AFib) and heart failure (HF) in both DDD and VVI mode. RV pacing was linked with left ventricular (LV) dyssynchrony in almost 50% of patients with PM implant... |
14,269 | Left ventricular diastolic dysfunction in patients with metabolic syndrome. | Metabolic syndrome (MetS), which is a cluster of medical disorders, is common and it is associated with increased cardiovascular morbidity and mortality. The aim of this study was to evaluate the relationship between characteristics of metabolic syndrome and the grade of diastolic dysfunction. The study included 72 pat... |
14,270 | Acupuncture for paroxysmal and persistent atrial fibrillation: An effective non-pharmacological tool? | In Traditional Chinese Medicine, stimulation of the Neiguan spot has been utilized to treat palpitations and symptoms related to different cardiovascular diseases. We evaluated whether acupuncture might exert an antiarrhythmic effect on patients with paroxysmal or persistent atrial fibrillation (AF). Two sets of data a... |
14,271 | Antithrombotic therapy for stroke prevention in patients with heart failure. | Congestive heart failure (CHF) is associated with an increased risk of stroke mainly due stasis leading to increased risk of thrombus formation in the left ventricle and subsequent cerebral embolism. CHF patients are also at increased risk of atrial fibrillation (AF) that also leads to cerebral embolism. Aggressive med... |
14,272 | Prognostic value of QRS fragmentation in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia. | QRS fragmentation, including epsilon potentials, terminal activation delay and prolonged S wave upstroke, has been recently described as a diagnostic criterion of arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D). Whether QRS fragmentation is a marker of recurrent ventricular tachycardia, primary ventr... |
14,273 | Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs. | Despite favorable metabolic and vascular effects, thiazolidinedione (TZD) drugs have not convincingly reduced cardiovascular mortality in clinical trials, raising the possibility of countervailing, off-target effects. We previously showed that TZDs block cardiac ATP-sensitive potassium (K(ATP)) channels in pigs. In thi... |
14,274 | Early repolarization and short QT interval in healthy subjects. | An early repolarization (ER) pattern is common in ECGs from patients with ventricular fibrillation (VF). These patients with ER have shorter QT intervals. Morphological variants of the ER pattern also have been associated with idiopathic VF, but their prevalence in healthy subjects is unclear.</AbstractText>The purpose... |
14,275 | Effects of ventricular pacing protocol on electrical restitution assessments in guinea-pig heart. | The steep slope of the rate adaptation of ventricular action potential duration (APD) is thought to indicate profibrillatory tendency. In cardiac patients, APD restitution is commonly assessed by extrasystolic (S(1)-S(2)) stimulations rather than dynamic pacing, because the latter may provoke myocardial ischaemia. In t... |
14,276 | A novel, minimally invasive, segmental myocardial infarction with a clear healed infarct borderzone in rabbits. | Ventricular arrhythmias in the setting of a healed myocardial infarction have been studied to a much lesser degree than acute and subacute infarction, due to the pericardial scarring, which results from the traditional open-chest techniques used for myocardial infarction (MI) induction. We sought to develop a segmental... |
14,277 | Long-term results of mitral repair for functional mitral regurgitation in idiopathic dilated cardiomyopathy. | While the results of mitral repair in ischaemic mitral regurgitation have been repeatedly reported, less data are available about the outcome of surgical repair of functional mitral regurgitation (FMR) in idiopathic dilated cardiomyopathy (iDCM) which represents the topic of this study.</AbstractText>Fifty-four iDCM pa... |
14,278 | Clinical context and mechanism of functional tricuspid regurgitation in patients with and without pulmonary hypertension. | Functional tricuspid regurgitation (FTR) with structurally normal valve is of poorly defined mechanisms. Prevalence and clinical context of idiopathic FTR (Id-FTR) (without overt TR cause) are unknown.</AbstractText>To investigate prevalence, clinical context, and mechanisms specific to FTR types, Id-FTR versus pulmona... |
14,279 | Sevoflurane postconditioning attenuates reperfusion-induced ventricular arrhythmias in isolated rat hearts exposed to ischemia/reperfusion injury. | Sevoflurane postconditioning has been proven to protect the hearts against ischemia/reperfusion injury, manifested mainly by improved cardiac function, reduced myocardial specific biomarker release, and decreased infarct size. This study is to observe the effects of sevoflurane postconditioning on reperfusion-induced v... |
14,280 | Perivertebral B-cell lymphoma in a Queensland koala (Phascolarctos cinereus adustus) with paralytic symptoms in the hind limbs. | A male Queensland koala (Phascolarctos cinereus adustus) at Kanazawa Zoological Gardens (Kanagawa, Japan) exhibited paralytic symptoms in the hind limbs. Computed tomography and magnetic resonance imaging revealed a mass on the left ventral side of the 11th to 13th thoracic vertebrae, and the presence of myelitis or ed... |
14,281 | Female sex is not associated with improved rates of ROSC or short term survival following prolonged porcine ventricular fibrillation. | There may be a survival benefit in female patients experiencing cardiac arrest, which could affect the interpretation of in vivo animal studies. We hypothesized that sex predicts return of spontaneous circulation (ROSC) and short-term survival (SURV) in porcine studies of prolonged ventricular fibrillation (VF).</Abstr... |
14,282 | Effects of isoproterenol and propranolol on the inducibility and frequency of ventricular fibrillation in patients with Brugada syndrome. | Isoproterenol (ISP), a beta-adrenergic agonist, suppresses arrhythmic storm in patients with sporadic Brugada syndrome (BS). However, the influence of ISP and the beta-adrenergic antagonist propranolol (PRO) on the inducibility and frequency of ventricular fibrillation (VF) in BS patients remains unclear.</AbstractText... |
14,283 | Association between clinical outcome and antiarrhythmic treatment in heart failure patients who have atrial fibrillation upon admission to the hospital. | Atrial fibrillation (AF) and heart failure (HF) are associated with significant mortality and morbidity. We sometimes encounter patients who have AF upon admission to the hospital, but it spontaneously converts to sinus rhythm within several days (i.e. converter).</AbstractText>We examined the association between the o... |
14,284 | Relationship between 24-h Holter recordings and clinical outcomes in patients with permanent atrial fibrillation. | This study aimed to test the hypothesis that the range of 24-h total heart beats (24 h-tHB) correlates with cardiac outcomes (cardiac death and incidence of hospitalization with heart failure) in patients with permanent atrial fibrillation (AF).</AbstractText>We divided 252 consecutive outpatients with permanent AF int... |
14,285 | Prediction of surgical outcome after aortic valve replacement. | Aortic valve replacement has some major adverse outcomes. For these, the predictors need identification.</AbstractText>This was a retrospective file study of 1000 consecutive patients who underwent AVR for degenerative aortic valve disease. Twenty-five preoperative and 5 peroperative factors were screened by a univaria... |
14,286 | Early repolarisation: controversies and clinical implications. | Early repolarisation was previously considered a benign variant but in recent years has emerged as a marker of risk for sudden death. In part, this appears to reflect a change in the definition. ECG territory, degree of J-point elevation and ST-segment morphology are associated with different degrees of risk for subseq... |
14,287 | Effect of ramipril on the electrophysiological characteristics of ventricular myocardium after myocardial infarction in rabbits. | The current study aims to explore the effect of ramipril on the occurrence of ventricular arrhythmias and its possible mechanism after myocardial infarction (MI) in rabbits.</AbstractText>A total of 24 rabbits were divided into three groups: the sham operation group (SHAM), the MI group, and the ramipril group (RAM). A... |
14,288 | Prevalence of prominent J waves in patients presenting with ventricular fibrillation without structural heart disease: a single-center study. | Association between sudden cardiac arrest and early repolarization (QRS slurring in the inferolateral leads) has drawn recent attention. We retrospectively assessed the prevalence of electrocardiographic J waves in 19 men aged 46.5±13.7 years who, between 1979 and 2011, were resuscitated after cardiac arrest due t... |
14,289 | Determinants of atrial fibrillation in an animal model of obesity and acute obstructive sleep apnea. | Obesity and obstructive sleep apnea (OSA) are risk factors for atrial fibrillation (AF), but the underlying mechanisms are poorly understood.</AbstractText>The purpose of this study was to assess the mechanisms underlying AF promotion by obesity and OSA in rat models.</AbstractText>Zucker obese rats (ORs) and lean rats... |
14,290 | Usefulness of SUM of ST-segment elevation on electrocardiograms (limb leads) for predicting in-hospital complications in patients with stress (takotsubo) cardiomyopathy. | Although the prognosis of patients with stress (takotsubo) cardiomyopathy is relatively favorable, serious complications occur in some patients. It is generally accepted that electrocardiography is an essential tool for the diagnosis of stress cardiomyopathy, with findings highly suggestive of the characteristics of my... |
14,291 | Dexrazoxane provided moderate protection in a catecholamine model of severe cardiotoxicity. | Positive effects of dexrazoxane (DEX) in anthracycline cardiotoxicity have been mostly assumed to be associated with its iron-chelating properties. However, this explanation has been recently questioned. Iron plays also an important role in the catecholamine cardiotoxicity. Hence in this study, the influence of DEX on ... |
14,292 | Clinical impact of atrial fibrillation in patients with pulmonary hypertension. | Pulmonary hypertension (PH) is associated with progressive impairment of right ventricular function, reduced exercise capacity and a poor prognosis. Little is known about the prevalence, clinical manifestation and impact of atrial fibrillation (AF) on cardiac function in PH.</AbstractText>In a four year single-centre r... |
14,293 | Atrioventricular nodal ablation in atrial fibrillation: a meta-analysis of biventricular vs. right ventricular pacing mode. | For patients with refractory atrial fibrillation (AF) undergoing atrioventricular nodal ablation (AVNA), initial single-chamber right ventricular (RV)-only pacing is standard. Given the deleterious effects of chronic RV-only pacing, the impact of an initial biventricular (BiV) pacing strategy post-ablation is of intere... |
14,294 | Safety of flecainide. | Flecainide is a class Ic antiarrhythmic agent that has an important role as part of rhythm control strategies in patients with atrial fibrillation (AF). Early clinical data on the use of flecainide showed an increase in arrhythmias and mortality compared with placebo in patients with a previous myocardial infarction an... |
14,295 | Catheter ablation of ventricular fibrillation triggers and electrical storm. | Ventricular fibrillation (VF) and electrical storm remain challenging conditions to manage despite the availability of various treatment modalities. Insertion of an implantable cardioverter defibrillator (ICD) remains the gold standard method for lowering the risk of sudden cardiac death in patients deemed to be at gre... |
14,296 | Embozene™ microspheres induced nonreperfused myocardial infarction in an experimental swine model. | To develop a magnetic resonance imaging (MRI) compatible, percutaneous technique for the generation of nonreperfused myocardial infarct (MI).</AbstractText>Modeling nontreated MI has major importance in the development and preclinical testing of new therapeutic strategies for patients missing the time window suitable f... |
14,297 | [A 59 year-old patient with acute anterolateral myocardial infarction, complicated by cardiogenic shock, with chest wall deformity caused by Heine-Medin disease]. | We report a case of a 59 year-old patient in a condition of acute myocardial infarction with ST elevation, in a cardiogenic shock, with multiple cardiac arrests in mechanism of ventricular fibrillation with a significant chest wall deformity caused by Heine-Medin disease in childhood. To our knowledge, this is the firs... |
14,298 | Oesophageal cancer with myocardial metastasis complicated by ventricular fibrillation: the role of echocardiography. | Myocardial metastasis from oesophageal cancer is very rare, and is usually detected as part of widespread metastases in the terminal stage. It is rare to detect a solitary metastasis. We present a case of solitary myocardial metastasis from distal oesophagus complicated by ventricular fibrillation. |
14,299 | Controlled pauses at the initiation of sodium nitroprusside-enhanced cardiopulmonary resuscitation facilitate neurological and cardiac recovery after 15 mins of untreated ventricular fibrillation. | A multipronged approach to improve vital organ perfusion during cardiopulmonary resuscitation that includes sodium nitroprusside, active compression-decompression cardiopulmonary resuscitation, an impedance threshold device, and abdominal pressure (sodium nitroprusside-enhanced cardiopulmonary resuscitation) has been r... |
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