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2,326,900 | The physiological uptake pattern of (18)F-FDG in the left ventricular myocardium of patients without heart disease. | The purpose of this study was to evaluate the physiological uptake pattern of (18)F-FDG in the left ventricular myocardium of patients under preparation for tumor FDG-PET.</AbstractText>We enrolled 188 patients without cardiac disease. The accumulation patterns were classified as either 'none', 'diffuse', 'focal' or 'f... |
2,326,901 | Embolization of a fractured central venous catheter placed using the internal jugular approach. | Fracture and embolization of central venous catheters placed via the subclavian approach is well recognized, but fractured catheters placed via the internal jugular vein are extremely rare.</AbstractText>A 65-year-old man presented with a catheter embolus after placement of a central venous port using the internal jugu... |
2,326,902 | Noggin improves ischemic brain tissue repair and promotes alternative activation of microglia in mice. | We previously reported that bone morphogenetic proteins (BMPs) and their endogenous antagonist noggin are expressed in the brain weeks after an ischemic insult. Here, to define their roles in ischemic brain tissue repair and remodeling, we infused recombinant BMP7 or noggin into the ipsilateral ventricle of mice for 2w... |
2,326,903 | Differential effects of temperature and glucose on glycogenolytic enzymes in tissues of rainbow trout (Oncorhynchus mykiss). | The pathways and regulatory mechanisms of glycogenolysis remain relatively unexplored in non-mammalian vertebrates, especially poikilotherms. We studied the temperature sensitivity and inhibition of glycogenolytic enzymes in liver, ventricle, and white muscle of rainbow trout acclimated to 14 °C. Glycogen phosphor... |
2,326,904 | Bioinformatics analysis of time series gene expression in left ventricle (LV) with acute myocardial infarction (AMI). | This study is to investigate the key genes and their possible function in acute myocardial infarction (AMI). The data of GSE4648 downloaded from the Gene Expression Omnibus (GEO) database include 6 time points (15 min, 60 min, 4h, 12h, 24h and 48 h) of 12 left ventricle (LV) samples, 12 surviving LV free wall (FW) samp... |
2,326,905 | The disastrous "sun ray" sign in cardiac magnetic resonance: an indicator of angiosarcoma. | Distinguishing the benign and malignant cardiac masses is usually a diagnostic challenge, and safe, non-invasive, and reliable techniques are necessary to avoid any delay in treatment. The previously described "sun ray" appearance is an important sign in the diagnosis of cardiac angiosarcoma, and in this report we pres... |
2,326,906 | Neuroendoscopic lavage for the treatment of intraventricular hemorrhage and hydrocephalus in neonates. | Object Neonatal intraventricular hemorrhage (IVH) may evolve into posthemorrhagic hydrocephalus and cause neurodevelopmental impairment. In this study, an endoscopic surgical approach directed toward the removal of intraventricular hematoma was evaluated for its safety and efficacy. Methods Between August 2010 and Dece... |
2,326,907 | [Hyponatremia caused by SIADH following endoscopic third ventriculostomy: a case report]. | A 25-year-old man complained of disorientation and gait disturbance during the past 2 weeks. The patient had been treated for cerebellar astrocytoma by open surgery thrice, at ages 3, 5, and 11. Ventriculo-peritoneal shunt was performed for postoperative hydrocephalus at the age of 11. Magnetic resonance imaging(MRI)sh... |
2,326,908 | Neuropeptide Y and leptin sensitivity is dependent on diet composition. | Rats on different free-choice (fc) diets for 1 week of either chow, saturated fat and liquid sugar (fcHFHS), chow and saturated fat (fcHF), or chow and liquid sugar (fcHS) have differential levels of neuropeptide Y (NPY) mRNA in the arcuate nucleus. Because these differences were not explained by plasma leptin levels b... |
2,326,909 | Ciliopathy is differentially distributed in the brain of a Bardet-Biedl syndrome mouse model. | Bardet-Biedl syndrome (BBS) is a genetically heterogeneous inherited human disorder displaying a pleotropic phenotype. Many of the symptoms characterized in the human disease have been reproduced in animal models carrying deletions or knock-in mutations of genes causal for the disorder. Thinning of the cerebral cortex,... |
2,326,910 | Association of amyloid burden, brain atrophy and memory deficits in aged apolipoprotein ε4 mice. | Apolipoprotein E ε4 allele (ApoE4) has been associated with increased risk of sporadic Alzheimer's disease (AD) and of conversion from mild cognitive impairment to AD. But the underlying mechanism of ApoE4 affecting brain atrophy and cognition is not fully understood. We investigated the effect of ApoE4 on amyloi... |
2,326,911 | Supratricuspid obstructive membrane in congenitally corrected transposition of the great arteries. | Obstructive lesions in the inflow of the systemic ventricle in congenitally corrected transposition of the great arteries are rare. It is important to identify such lesion which could alter the surgical outcome if not recognized. We report the echocardiographic findings in a patient with supratricuspid obstructive memb... |
2,326,912 | Left and right ventricular lead positions are imprecisely determined by fluoroscopy in cardiac resynchronization therapy: a comparison with cardiac computed tomography. | Fluoroscopy is the routine method for localizing left ventricular (LV) and right ventricular (RV) lead positions in cardiac resynchronization therapy (CRT). However, the ability of fluoroscopy to determine lead positions in a standard ventricular segmentation is unknown. We aimed to evaluate the accuracy and reproducib... |
2,326,913 | Aortic pulse wave velocity is associated with measures of subclinical target organ damage in patients with mild hypertension. | We evaluated the temporal association between aortic arterial stiffness and subclinical target organ damage, including renal function decline, left ventricular geometric remodeling, and left ventricular diastolic dysfunction in patients with mild hypertension. Automatic pulse wave velocity (PWV) measuring system was ap... |
2,326,914 | Distributed MRI reconstruction using Gadgetron-based cloud computing. | To expand the open source Gadgetron reconstruction framework to support distributed computing and to demonstrate that a multinode version of the Gadgetron can be used to provide nonlinear reconstruction with clinically acceptable latency.</AbstractText>The Gadgetron framework was extended with new software components t... |
2,326,915 | Vitronectin-binding PAI-1 protects against the development of cardiac fibrosis through interaction with fibroblasts. | Plasminogen activator inhibitor-1 (PAI-1) promotes or abates fibrotic processes occurring in different organs. Binding of PAI-1 to vitronectin, an extracellular matrix component, may inhibit vitronectin-integrin complex-mediated cellular responses in pathophysiological conditions. To investigate the importance of plasm... |
2,326,916 | Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways. | Apelin has been proved to protect the heart against ischemia/reperfusion (I/R) injury via the activation of phosphatidylinositol 3-kinase (PI3K)/Akt and extracellular signal-regulated kinase (ERK) signaling pathways. Whether this protective effect applies to brain I/R injury needed to be explored. We therefore investig... |
2,326,917 | Magnetic Resonance Imaging Tracking of Graft Survival in the Infarcted Heart: Iron Oxide Particles Versus Ferritin Overexpression Approach. | The main objective of cell therapy is the regeneration of damaged tissues. To distinguish graft from host tissue by magnetic resonance imaging (MRI), a paramagnetic label must be introduced to cells prior to transplantation. The paramagnetic label can be either exogenous iron oxide nanoparticles or a genetic overexpres... |
2,326,918 | Life-threatening cardiac tamponade: a rare complication of acupuncture. | Acupuncture as an ancient Chinese treatment has proven effective and is utilized worldwide. Although it is generally believed to be a safe clinical procedure, serious lethal complications including death have been reported. We present a rare case of life-threatening cardiac tamponade due to penetration of an acupunctur... |
2,326,919 | Relationship of age with the size of the interventricular foramina and aqueductus sylvii: a morphometric evaluation. | The ventricular system is an essential part of the brain. Various pathologies directly or indirectly affect the size of this system. Morphometric analysis of the cerebral ventricular system is important for evaluating changes due to growth, aging, and intrinsic and extrinsic pathologies. The aim of this study was to ev... |
2,326,920 | Pimobendan improves right ventricular myocardial contraction and attenuates pulmonary arterial hypertension in rats with monocrotaline-induced pulmonary arterial hypertension. | The present study aimed to evaluate the therapeutic effect of pimobendan treatment for pulmonary hypertension (PH) in rats administered monocrotaline (MCT).</AbstractText>Fifty-four 12-week-old male Sprague-Dawley rats were injected with monocrotaline or saline solution. Serial echocardiography and right ventricular sy... |
2,326,921 | Multiframe registration of real-time three-dimensional echocardiography time series. | Mosaicing of real-time three-dimensional echocardiography (RT3-DE) images aims at extending the field-of-view of overlapping images. Currently available methods discard most of the temporal information available in the time series. We investigate the added value of simultaneous registration of multiple temporal frames ... |
2,326,922 | Magnetic resonance imaging of single co-labeled mesenchymal stromal cells after intracardial injection in mice. | The aim of this study was to establish co-labeling of mesenchymal stromal cells (MSC) for the detection of single MSC in-vivo by MRI and histological validation.</AbstractText>Mouse MSC were co-labeled with fluorescent iron oxide micro-particles and carboxyfluorescein succinimidyl ester (CFSE). The cellular iron conten... |
2,326,923 | Multiple mechanisms mediate the taurine-induced proliferation of neural stem/progenitor cells from the subventricular zone of the adult mouse. | Taurine was previously reported to increase the proliferation of neural precursor cells (NPCs) from subventricular zone of the mouse brain. The results of a study that aimed to understand the mechanisms of this effect are presented here. Because taurine was not found in NPC nuclei, direct interactions with nuclear elem... |
2,326,924 | Negative impact of a cadmium concentration considered environmentally safe in Brazil on the cardiac performance of bullfrog tadpoles. | A drastic amphibian decline has been observed worldwide, which can be attributed (among other factors) to exposure to pollutants. Considering that cadmium corresponds to the most rapidly increasing trace metal in the environment, the aim of this work was to evaluate whether the exposure (2 and 16 days) of bullfrog tadp... |
2,326,925 | On the value of seasonal mammals for identifying mechanisms underlying the control of food intake and body weight. | This article is part of a Special Issue "Energy Balance". Seasonal cycles of adiposity and body weight reflecting changes in both food intake and energy expenditure are the norm in mammals that have evolved in temperate and polar habitats. Innate circannual rhythmicity and direct responses to the annual change in photo... |
2,326,926 | Bone morphogenetic protein-4 inhibits adult neurogenesis and is regulated by fractone-associated heparan sulfates in the subventricular zone. | Fractones are extracellular matrix structures that display a fractal ultrastructure and that are visualized as puncta after immunolabeling for laminin or heparan sulfate proteoglycans. In the adult brain, fractones are found throughout the subventricular zone (SVZ). The role of fractones is just emerging. We have recen... |
2,326,927 | The role of the sympathetic nervous system in the resuscitative effect of stimulating the central serotonin 1A receptors in haemorrhagic shock in rats. | Haemorrhagic shock is a life threatening condition, and, as such, it is important to understand the mechanisms taking part in its reversal. In the 1990s, it was shown that activation of serotonin 1A receptors is responsible for the circulatory decompensation and development of the sympathoinhibitory phase. In previous ... |
2,326,928 | Resolution of papilledema after endoscopic third ventriculostomy versus cerebrospinal fluid shunting in hydrocephalus: a comparative study. | In this study the authors compare the efficacy of endoscopic third ventriculostomy (ETV) versus CSF shunting for resolution of papilledema in hydrocephalus.</AbstractText>This comparative case series study recruited 12 patients (24 eyes) with hydrocephalus who underwent either an ETV (Group 1, 6 patients [12 eyes]) or ... |
2,326,929 | Bilateral telovelar approach: A safe route revisited for resections of various large fourth ventricle tumors. | Tumors located in the posterior fossa and especially in the middle and upper fourth ventricle are comparatively rare and technically very challenging. For some lesions, the telovelar approach has been shown to be a suitable approach. The unilateral approach is sufficient in most cases of small lesions. However, large f... |
2,326,930 | The "extended" endoscopic endonasal approach for the removal of a mixed intrasuprasellar germinoma: Technical case report. | Intracranial germ cell tumors (GCTs) represent less than 5% of pediatric brain tumors. Neurosurgical treatment remains essential in the management of patients with intracranial nongerminomatous GCT.</AbstractText>A 12-year-old girl presented with clinical features of neurohypophyseal dysfunction and rapidly progressive... |
2,326,931 | Age-related changes in astrocytic and ependymal cells of the subventricular zone. | Neurogenesis persists in the adult subventricular zone (SVZ) of the mammalian brain. During aging, the SVZ neurogenic capacity undergoes a progressive decline, which is attributed to a decrease in the population of neural stem cells (NSCs). However, the behavior of the NSCs that remain in the aged brain is not fully un... |
2,326,932 | GSK3β regulates oligodendrogenesis in the dorsal microdomain of the subventricular zone via Wnt-β-catenin signaling. | Oligodendrocytes, the myelinating cells of the CNS, are derived postnatally from oligodendrocyte precursors (OPs) of the subventricular zone (SVZ). However, the mechanisms that regulate their generation from SVZ neural stem cells (NSC) are poorly understood. Here, we have examined the role of glycogen synthase kinase 3... |
2,326,933 | Evaluation of left ventricle functions by tissue Doppler, strain, and strain rate echocardiography in patients with primary hyperparathyroidism. | Cardiovascular morbidity and mortality are increased in patients with primary hyperparathyroidism (PHPT). We aimed to evaluate left ventricle systolic and diastolic functions with tissue Doppler imaging (TDI) and strain and strain rate echocardiography in patients with PHPT. Thirty-one patients with PHPT and 29 healthy... |
2,326,934 | Influence of term of exposure to high-fat diet-induced obesity on myocardial collagen type I and III. | Obesity is a risk factor for many medical complications; medical research has shown that hemodynamic, morphological and functional abnormalities are correlated with the duration and severity of obesity.</AbstractText>Present study determined the influence of term of exposure to high-fat diet-induced obesity on myocardi... |
2,326,935 | Effects of glucocorticoid exposure on growth and structural maturation of the heart of the preterm piglet. | Inadequate maintenance of systemic blood flow in neonates following preterm birth is associated with increased morbidity and mortality, and may be due in part to structural immaturity of the myocardium. Maternal glucocorticoid administration is associated with improved cardiovascular function, and possibly promotes str... |
2,326,936 | Prognostic value of serum uric acid: new-onset in and out-of-office hypertension and long-term mortality. | Serum uric acid (SUA) has been associated with an increased cardiovascular risk, but no conclusive evidence exists on whether it is an independent risk factor or a reflection of other risk factors to which it is related. We examined the relationship of SUA with a number of cardiovascular variables [including risk facto... |
2,326,937 | Bidirectional crosstalk between periventricular endothelial cells and neural progenitor cells promotes the formation of a neurovascular unit. | Interactions between neural progenitor cells (NPC) and endothelial cells (EC) from adult vascular beds have been well explored previously. However, the factors and signaling mechanisms that regulate neurogenesis and angiogenesis are most prevalent during embryonic development. This study aimed to determine whether embr... |
2,326,938 | Vitamin D and brain volumetric changes: Systematic review and meta-analysis. | Vitamin D has multiple functions in the nervous system. Our objective was to systematically review and quantitatively synthesize evidence on the location and nature of brain morphometric changes linked to vitamin D depletion or repletion. A Medline search was conducted in February 2014, without limit of date and langua... |
2,326,939 | Late-onset Alzheimer disease genetic variants in posterior cortical atrophy and posterior AD. | To investigate association of genetic risk factors for late-onset Alzheimer disease (LOAD) with risk of posterior cortical atrophy (PCA), a syndrome of visual impairment with predominant Alzheimer disease (AD) pathology in posterior cortical regions, and with risk of "posterior AD" neuropathology.</AbstractText>We asse... |
2,326,940 | [Myocardial injury in rats following a sudden increase of altitudes]. | To investigate the influence of a sudden increase of altitudes (within 2500 m) in winter on cardiomyocyte functions in rats.</AbstractText>Thirty male Wistar rats were randomly divided into groups A (55 m), B (1520 m), and C (2260 m) and subjected to simulated conditions at the indicated altitudes in winter for 3 days.... |
2,326,941 | Superficial siderosis of the central nervous system caused by hemorrhagic intraventricular craniopharyngioma: case report and literature review. | Superficial siderosis is a rare condition caused by hemosiderin deposits in the central nervous system (CNS) due to prolonged or recurrent low-grade bleeding into the cerebrospinal fluid (CSF). CNS tumor could be one of the sources of bleeding, both pre- and postoperatively. We report an extremely rare case of superfic... |
2,326,942 | Fetal nuchal fold thickness measurement between 18 and 24 weeks of pregnancy: reference intervals for a Brazilian population. | To determine reference intervals of fetal nuchal fold (NF) thickness measurement in the second trimester of pregnancy in a Brazilian population.</AbstractText>This was a retrospective cross-sectional study with 2559 normal singleton pregnancies between 18 and 24 weeks of pregnancy. The fetal NF was obtained in the axia... |
2,326,943 | Testing for association of the monoamine oxidase A promoter polymorphism with brain structure volumes in both autism and the fragile X syndrome. | Autism and the fragile X syndrome (FXS) are related to each other genetically and symptomatically. A cardinal biological feature of both disorders is abnormalities of cerebral cortical brain volumes. We have previously shown that the monoamine oxidase A (MAOA) promoter polymorphism is associated with cerebral cortical ... |
2,326,944 | [Post-training N-methyl-D-aspartate receptor blockade facilitates retention of acquired spatial memory in rats]. | We investigated the effect of a post-training chronic infusion of N-methyl-D-aspartate (NMDA) receptor blocker on retention of spatial reference memory in rats. In Experiment 1, we trained 4 groups of rats for 4 days (4 trials/ day) in the Morris water maze task. In a single probe trial after retention intervals of 1, ... |
2,326,945 | Antiaging properties of a grape-derived antioxidant are regulated by mitochondrial balance of fusion and fission leading to mitophagy triggered by a signaling network of Sirt1-Sirt3-Foxo3-PINK1-PARKIN. | It was proposed that resveratrol, a polyphenolic antioxidant and a calorie restriction mimetic could promote longevity but subsequent studies could not prove this. The original proposal was based on the fact that a grape-derived antioxidant could activate the antiaging gene Sirt1. Most studies agree that indeed grape a... |
2,326,946 | Thymic stromal lymphopoietin is expressed in the intact central nervous system and upregulated in the myelin-degenerative central nervous system. | Thymic stromal lymphopoietin (TSLP) is an epithelial cytokine expressed at barrier surfaces of the skin, gut, nose, lung, and the maternal/fetal interphase. At these sites, it is important for the generation and maintenance of non-inflammatory, tissue-resident dendritic cell responses. We show here that TSLP is also ex... |
2,326,947 | Relationship between survival and increased radiation dose to subventricular zone in glioblastoma is controversial. | To test the hypothesis on prolonged survival in glioblastoma cases with increased subventricular zone (SVZ) radiation dose. Sixty glioblastoma cases were previously treated with adjuvant radiotherapy and Temozolamide. Ipsilateral, contralateral and bilateral SVZs were contoured and their doses were retrospectively eval... |
2,326,948 | Role of red blood cell lysis and iron in hydrocephalus after intraventricular hemorrhage. | Thrombin and iron are two major players in intracerebral hemorrhage-induced brain injury and our recent study found that thrombin contributes to hydrocephalus development in a rat model of intraventricular hemorrhage (IVH). This study investigated the role of red blood cell (RBC) lysis and iron in hydrocephalus after I... |
2,326,949 | The influence of the region of interest width on two-dimensional speckle tracking-based measurements of strain and strain rate. | There are significant variations in the published normal values of two-dimensional speckle tracking-derived strain and strain rate. These occur even when authors use the same software. To measure strain, the operator creates a region of interest (ROI) to define the myocardium to be analyzed. The purpose of this study w... |
2,326,950 | Fetal onset ventriculomegaly and subependymal cysts in a pyridoxine dependent epilepsy patient. | Pyridoxine dependent epilepsy (PDE) is caused by mutations in the ALDH7A1 gene encoding α-aminoadipic semialdehyde dehydrogenase. The classic clinical presentation is neonatal seizures responsive only to pyridoxine therapy. White matter abnormalities, corpus callosum agenesis or hypoplasia, megacisterna magna, co... |
2,326,951 | A rare presentation of myocardial plasmacytoma assessed by FDG PET/CT. | We describe a rare case of myocardial plasmacytoma staged and followed up with FDG PET/CT. A 72-year-old man was incidentally identified with a right ventricular apical mass, which was pathologically confirmed to be a plasmacytoma. A pre-treatment FDG PET/CT scan subsequently showed lesions not only in the right ventri... |
2,326,952 | Ferritin H gene deletion in the choroid plexus and forebrain results in hydrocephalus. | Ferritin H, the major iron storage protein, has essential functions in early embryonic development as well as in adult liver and intestine. To address the question whether ferritin H has similarly essential functions in the brain we used the Cre/loxP system to generate mice with a forebrain-specific inactivation of the... |
2,326,953 | Left ventricular vortices as observed by vector flow mapping: main determinants and their relation to left ventricular filling. | Swirling flow, organized in vortices, contributes to adequate left ventricular function. In this study, we apply a novel echocardiographic flow-mapping technique, vector flow mapping (VFM), to evaluate the main characteristics of left ventricular vortices and its relation to filling parameters.</AbstractText>Forty-eigh... |
2,326,954 | Effect of transplantation of human embryonic stem cell-derived neural progenitor cells on adult neurogenesis in aged hippocampus. | Adult neurogenesis occurs within the special microenvironment in the subgranular zone of the hippocampus and the subventricular zone of the lateral ventricle of the mammalian brain. The special microenvironment is known as neurogenic niches. Multiple cell types, including endothelial cells, astroglia, ependymal cells, ... |
2,326,955 | Relation between Red Cell Distribution Width and Left Ventricular Function in Children with Heart Failure. | Background. Most of the studies done on adults showed that red cell distribution width (RDW) can be used as a prognostic marker in patients with chronic heart failure. However, RDW has not been tested in children with heart failure. Methods and Results. 31 children with heart failure admitted to Cardiology Unit, Tanta ... |
2,326,956 | Reference range of fetal transverse cerebellar diameter between 18 and 24 weeks of pregnancy in a Brazilian population. | To determine a reference range of fetal transverse cerebellar diameter in Brazilian population. This was a retrospective cross-sectional study with 3772 normal singleton pregnancies between 18 and 24 weeks of pregnancy. The transverse cerebellar diameter was measured on the axial plane of the fetal head at the level of... |
2,326,957 | Accelerated human cardiac diffusion tensor imaging using simultaneous multislice imaging. | To demonstrate the feasibility of accelerating measurements of cardiac fiber structure using simultaneous multislice (SMS) imaging.</AbstractText>SMS excitation with a blipped controlled aliasing (CAIPI) readout was incorporated into a diffusion-encoded stimulated echo pulse sequence to obtain diffusion measurements in... |
2,326,958 | Motion correction of multi-contrast images applied to T₁and T₂quantification in cardiac MRI. | The ability to manipulate image contrast and thus to obtain complementary information is one of the main advantages of MRI. Motion consistency within the whole data set is a key point in the context of multi contrast imaging. In cardiac and abdominal MRI, the acquisition strategy uses multiple breath-holds and often re... |
2,326,959 | Direct estimation of cardiac biventricular volumes with an adapted Bayesian formulation. | Accurate estimation of the ventricular volumes is essential to the assessment of global cardiac functions. The existing estimation methods are mostly restricted to the left ventricle (LV), and often require segmentation which is challenging and computationally expensive. This paper proposes to estimate the volumes of b... |
2,326,960 | Automatic segmentation of a fetal echocardiogram using modified active appearance models and sparse representation. | A novel approach is presented to automatically segment the left ventricle in fetal echocardiograms. The proposed approach strategically integrates sparse representation, global constraint, and local refinement algorithms into an active appearance model (AAM) framework. In the training stage, we construct an enhanced AA... |
2,326,961 | Cardiac aging is initiated by matrix metalloproteinase-9-mediated endothelial dysfunction. | Aging is linked to increased matrix metalloproteinase-9 (MMP-9) expression and extracellular matrix turnover, as well as a decline in function of the left ventricle (LV). Previously, we demonstrated that C57BL/6J wild-type (WT) mice > 18 mo of age show impaired diastolic function, which was attenuated by MMP-9 delet... |
2,326,962 | Intrastriatal transplantation of adenovirus-generated induced pluripotent stem cells for treating neuropathological and functional deficits in a rodent model of Huntington's disease. | Induced pluripotent stem cells (iPSCs) show considerable promise for cell replacement therapies for Huntington's disease (HD). Our laboratory has demonstrated that tail-tip fibroblasts, reprogrammed into iPSCs via two adenoviruses, can survive and differentiate into neuronal lineages following transplantation into heal... |
2,326,963 | Remodeling of the sarcomeric cytoskeleton in cardiac ventricular myocytes during heart failure and after cardiac resynchronization therapy. | Sarcomeres are the basic contractile units of cardiac myocytes. Recent studies demonstrated remodeling of sarcomeric proteins in several diseases, including genetic defects and heart failure. Here we investigated remodeling of sarcomeric α-actinin in two models of heart failure, synchronous (SHF) and dyssynchrono... |
2,326,964 | Functional and structural alterations of cardiac and skeletal muscle mitochondria in heart failure patients. | The fundamental mechanisms involved in the genesis and progression of heart failure are not clearly understood. The present study was conducted to analyze the cardiac mitochondrial involvement in heart failure, the possible parallelism between cardiac and skeletal muscle and if there is a link between clinical symptoms... |
2,326,965 | Angiotensin (1-7) re-establishes heart cell communication previously impaired by cell swelling: implications for myocardial ischemia. | The influence of hypertonic solution on dye coupling was investigated in cell pairs isolated from the left ventricle of adult Sprague Dawley rats.The hypertonic solution together with Lucifer Yellow CH, were dialyzed into one cell of the pair using the whole cell clamp tecnique, and the diffusion of dye in the dialyzed... |
2,326,966 | Genetic modification of the relationship between phosphorylated tau and neurodegeneration. | A subset of individuals present at autopsy with the pathologic features of Alzheimer's disease having never manifest the clinical symptoms. We sought to identify genetic factors that modify the relationship between phosphorylated tau (PTau) and dilation of the lateral inferior ventricles.</AbstractText>We used data fro... |
2,326,967 | Hurthle cell carcinoma presenting as a single choroid plexus metastasis. | Choroid plexus masses represent approximately 0.3-0.8% of intracranial tumors. Herein we present, to our knowledge, the first reported patient with an isolated Hurthle cell papillary thyroid carcinoma metastasis to the choroid plexus of the lateral ventricle. Unresponsive to iodine ablation and refusing surgery, the pa... |
2,326,968 | Dissociating effects of spatial learning from locomotor activity for ouabain-induced bipolar disorder-like rats. | Whether ouabain, a Na+ - and K+-activated adenosine triphosphatase inhibitor, mimics cognitive impairments that can be dissociated from motor effects in the bipolar disorder-like animal model remains unclear. Ouabain and the vehicle aCSF were microinjected into the left lateral ventricle immediately, after 4h, and afte... |
2,326,969 | Intramyocardial transplantation of cardiac telocytes decreases myocardial infarction and improves post-infarcted cardiac function in rats. | The midterm effects of cardiac telocytes (CTs) transplantation on myocardial infarction (MI) and the cellular mechanisms involved in the beneficial effects of CTs transplantation are not understood. In the present study, we have revealed that transplantation of CTs was able to significantly decrease the infarct size an... |
2,326,970 | Simultaneous subependymomas in monozygotic female twins: further evidence for a common genetic or developmental disorder background. | In this paper, a rare case of subependymoma of the fourth ventricle in identical female twins is reported. Magnetic resonance imaging and CT showed nearly identical locations of the tumors in the fourth ventricle and similar growth patterns of the tumors in both sisters. Likewise, postoperative histopathological analys... |
2,326,971 | A case of pontine tegmental cap dysplasia with comorbidity of oculoauriculovertebral spectrum. | Pontine tegmental cap dysplasia (PTCD) is a newly described brainstem malformation with distinct neuroimaging findings, characterized by a flattened ventral pons, cerebellar vermal hypoplasia and vaulted pontine tegmentum that forms a "caplike" or "beaklike" bulge projecting into the fourth ventricle. We describe a 3-m... |
2,326,972 | A multi-scanner study of subcortical brain volume abnormalities in schizophrenia. | Schizophrenia patients show significant subcortical brain abnormalities. We examined these abnormalities using automated image analysis software and provide effect size estimates for prospective multi-scanner schizophrenia studies. Subcortical and intracranial volumes were obtained using FreeSurfer 5.0.0 from high-reso... |
2,326,973 | Third ventricular atypical meningioma which recurred with further malignant progression. | Meningiomas in the third ventricle are rare, with only very few cases reported in the literature. We report a case of primary third ventricular anaplastic meningioma in a 49-year-old man who presented with progressive weakness of the left limbs and headache. Magnetic resonance imaging revealed a tumor which seemed to a... |
2,326,974 | Universal algorithm for diagnosis of biventricular capture in patients with cardiac resynchronization therapy. | An accurate and universal method for diagnosis of biventricular (BiV) capture using a standard 12-lead electrocardiogram (ECG) would be useful for assessment of cardiac resynchronization therapy (CRT) patients. Our objective was to develop and validate such an ECG method for BiV capture diagnosis that would be independ... |
2,326,975 | Innervation of the brain, intracerebral Schwann cells and intracerebral and intraventricular schwannomas. | The cerebral vasculature and the choroid plexus are innervated by peripheral nerves. The anatomy of the vascular supply to the brain and its related perivascular nerves is reviewed. Intracerebral and intraventricular schwannomas most likely come from neoplastic transformation of Schwann cells investing the perivascular... |
2,326,976 | Anaplastic ependymoma of the third ventricle. | Supratentorial ependymomas are rare, especially in the third ventricle. We report the case of an ependymoma of the posterior third ventricle that was endoscopically removed just by aspiration through a flexible scope. Histologically, beside the typical pattern of growth with perivascular pseudorosettes, the tumor featu... |
2,326,977 | Expression of MicroRNA-29 and Collagen in Cardiac Muscle after Swimming Training in Myocardial-Infarcted Rats. | Myocardial infarction (MI) is accompanied by cardiac growth, increased collagen deposition, cell death and new vascularization of the cardiac tissue, which results in reduced ventricular compliance. The MiRNA-29 family (29a, 29b, and 29c) targets mRNAs that encode collagens and other proteins involved in fibrosis. In t... |
2,326,978 | Granulomatosis with polyangiitis: recurrence presenting as ependimoplexitis. | A 55-year-old man with granulomatosis with polyangiitis (GPA) developed continuous parietal headache, malaise, nasal crusting and dry cough. Neurological exam revealed only left hand hypoesthesia in 4th and 5th finger. Brain MRI showed enlarged right choroid plexus, hyperintense periventricular white matter, thalami an... |
2,326,979 | Interpolation function estimates post mortem interval under ambient temperature correlating with blood ATP level. | We developed a mathematical model using interpolation function, to characterize the correlation between blood ATP levels in the right ventricle of rabbit and post mortem interval (PMI) at different ambient temperatures.</AbstractText>Forty-eight healthy rabbits were randomly divided into 6 groups of 8 each. The sacrifi... |
2,326,980 | Primary aspergillosis of bilateral laryngoceles. | Laryngocele is an abnormal dilatation of the saccule of laryngeal ventricle, which is usually unilateral and filled with air or fluid. We present a case of bilateral laryngoceles colonized by Aspergillus species. |
2,326,981 | Impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats. | Alterations in lipid metabolism within the heart may have a causal role in the establishment of diabetic cardiomyopathy; however, this remains equivocal. Therefore, in the current study we determined cardiac mitochondrial bioenergetics in ZDF rats before overt type 2 diabetes and diabetic cardiomyopathy developed. In a... |
2,326,982 | Spatiotemporal distribution of SUMOylation components during mouse brain development. | Posttranslational modification of proteins might play an important role in brain cellular dynamics via the rapid turnover or functional change of critical proteins controlling neuronal differentiation or synaptic transmission. Small ubiquitin-like modifier protein (SUMO) is a family of ubiquitin-like small proteins tha... |
2,326,983 | The adult macaque spinal cord central canal zone contains proliferative cells and closely resembles the human.<Pagination><StartPage>1800</StartPage><EndPage>1817</EndPage><MedlinePgn>1800-17</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/cne.23501</ELocationID><Abstract><AbstractText>The persi... | The persistence of proliferative cells, which could correspond to progenitor populations or potential cells of origin for tumors, has been extensively studied in the adult mammalian forebrain, including human and nonhuman primates. Proliferating cells have been found along the entire ventricular system, including aroun... |
2,326,984 | Central orexin inhibits reflex swallowing elicited by the superior laryngeal nerve via caudal brainstem in the rat. | We examined the effects of orexins on the reflex swallowing using anesthetized rats. Orexins were administered into the fourth ventricle. Swallowing was induced by repeated electrical stimulation of the central cut end of the superior laryngeal nerve (SLN) and was identified by the electromyogram lead penetrated the my... |
2,326,985 | Assessment of right ventricular responses to therapy in pulmonary hypertension. | Irrespective of its cause, pulmonary hypertension (PH) leads to an increase in pulmonary vascular resistance (PVR). Failing adaption of the right ventricle (RV) to the increased afterload is the main cause of death in PH patients and therefore monitoring RV function during treatment is essential. However, consensus on ... |
2,326,986 | NFκB signaling is essential for the lipopolysaccharide-induced increase of type 2 deiodinase in tanycytes. | The enzyme type 2 deiodinase (D2) is a major determinant of T₃ production in the central nervous system. It is highly expressed in tanycytes, a specialized cell type lining the wall of the third ventricle. During acute inflammation, the expression of D2 in tanycytes is up-regulated by a mechanism that is poorly ... |
2,326,987 | Low-dose acetazolamide reverses periventricular white matter hyperintensities in iNPH. | To assess the effects of low-dose acetazolamide treatment on volumetric MRI markers and clinical outcome in idiopathic normal-pressure hydrocephalus (iNPH).</AbstractText>We analyzed MRI and gait measures from 8 patients with iNPH with serial MRIs from an institutional review board-approved imaging protocol who had bee... |
2,326,988 | The orexin component of fasting triggers memory processes underlying conditioned food selection in the rat. | To test the selectivity of the orexin A (OXA) system in olfactory sensitivity, the present study compared the effects of fasting and of central infusion of OXA on the memory processes underlying odor-malaise association during the conditioned odor aversion (COA) paradigm. Animals implanted with a cannula in the left ve... |
2,326,989 | Rhombencephalosynapsis as a cause of aqueductal stenosis: an under-recognized association in hydrocephalic children. | Rhombencephalosynapsis is a rare genetic aberration characterized by variable vermian hypoplasia/aplasia in conjunction with united cerebellar hemispheres. Genetic defects in the isthmic organizer at the mesencephalic-metencephalic junction are presumably responsible for the associated aqueductal stenosis.</AbstractTex... |
2,326,990 | Role of dorsal vagal complex A2 noradrenergic neurons in hindbrain glucoprivic inhibition of the luteinizing hormone surge in the steroid-primed ovariectomized female rat: effects of 5-thioglucose on A2 functional biomarker and AMPK activity. | Neuro-glucostasis is required for normal expression of the steroid positive-feedback-induced preovulatory pituitary luteinizing hormone (LH) surge, a critical element of female reproduction. Glucoprivic signals from the caudal hindbrain restrain this surge, but the cellular source of this stimulus is unclear. Norepinep... |
2,326,991 | Estrogen receptor β and oxytocin interact to modulate anxiety-like behavior and neuroendocrine stress reactivity in adult male and female rats. | The hypothalamic-pituitary-adrenal (HPA) axis is activated in response to stressors and is controlled by neurons residing in the paraventricular nucleus of the hypothalamus (PVN). Although gonadal steroid hormones can influence HPA reactivity to stressors, the exact mechanism of action is not fully understood. It is kn... |
2,326,992 | Protective effect of geranylgeranylacetone via enhanced induction of HSPB1 and HSPB8 in mitochondria of the failing heart following myocardial infarction in rats. | The mechanisms underlying mitochondrial impairment in the failing heart are not yet clear. In a previous study, we found that the levels of small heat shock proteins (HSP) such as mitochondrial HSPB1 and HSPB8 in the failing heart following myocardial infarction were decreased. In the present study, to verify the hypot... |
2,326,993 | S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding. | The giant elastic protein titin is a determinant factor in how much blood fills the left ventricle during diastole and thus in the etiology of heart disease. Titin has been identified as a target of S-glutathionylation, an end product of the nitric-oxide-signaling cascade that increases cardiac muscle elasticity. Howev... |
2,326,994 | Effect of echocardiography-guided left ventricular lead placement for cardiac resynchronization therapy on mortality and risk of defibrillator therapy for ventricular arrhythmias in heart failure patients (from the Speckle Tracking Assisted Resynchronization Therapy for Electrode Region [STARTER] trial). | Echocardiography-guided left ventricular (LV) lead placement at the site of latest mechanical activation improves heart failure outcomes in patients receiving a cardiac resynchronization therapy defibrillator (CRT-D). In this study, we test the hypothesis that a strategy of echocardiography-guided LV lead placement imp... |
2,326,995 | Overexpression of microRNA-99a attenuates heart remodelling and improves cardiac performance after myocardial infarction. | MicroRNAs are involved in the regulation of various cellular processes, including cell apoptosis and autophagy. Expression of microRNA-99a (miR-99a) is reduced in apoptotic neonatal mice ventricular myocytes (NMVMs) subjected to hypoxia. We hypothesize that miR-99a might restore cardiac function after myocardial infarc... |
2,326,996 | Diffusion magnetic resonance imaging diagnostic relevance in pyogenic ventriculitis with an atypical presentation: a case report. | Pyogenic ventriculitis is a rare and severe cerebral infection characterized by the presence of suppurative fluid in the cerebral ventricles. It is a life-threatening condition and may present with an aspecific neurological picture. Brain imaging techniques usually demonstrate intraventricular debris and pus, but negat... |
2,326,997 | Neuroregeneration in the nucleus ambiguus after recurrent laryngeal nerve avulsion in rats. | The objective was to investigate neuroregeneration, the origins of newborn cells and the proliferation of neuronal and glial cells in the nucleus ambiguus (NA) after ipsilateral recurrent laryngeal nerve (RLN) avulsion.</AbstractText>All of the animals received a CM-Dil injection in the left lateral ventricle. Forty-fi... |
2,326,998 | Relationship of angiotensinase and vasopressinase activities between hypothalamus, heart, and plasma in L-NAME-treated WKY and SHR. | The renin-angiotensin system (RAS), vasopressin, and nitric oxide (NO) interact to regulate blood pressure at central and peripheral level. To improve our understanding of their interaction and their relationship with the hypothalamus and the cardiovascular system, we analyzed angiotensin- and vasopressin-metabolizing ... |
2,326,999 | Supratentorial extraventricular anaplastic ependymoma in a child. | A young child presented to the emergency department of a tertiary care hospital with on and off headache, focal seizures involving the left side of the body, weakness of left upper and lower limbs and vomiting for 2 weeks. Examination showed an alert child with grade 4/5 powers in left upper and lower limbs. Blood inve... |
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