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2,329,200
Pericytes in the infarcted heart.
The adult mammalian heart lacks regenerative capacity and heals through activation of an inflammatory cascade that leads to the formation of a collagen-based scar. Although scar formation is important to preserve the structural integrity of the ventricle, unrestrained inflammation and excessive fibrosis have been impli...
2,329,201
Detectability of the choroid plexus of the third ventricle with magnetic resonance ventriculography.
To clarify the detectability of the choroid plexus of the third ventricle (ChPl3V) with magnetic resonance ventriculography (MRVn) employing a steady-state free precession (SSFP) sequence in comparison to surgical endoscopic movies as a golden standard, as we encountered some clinical cases of total agenesis of corpus ...
2,329,202
Iodine Dose of Administered Contrast Media Affects the Level of Radiation-Induced DNA Damage During Cardiac CT Scans.
<b>OBJECTIVE.</b> The purpose of this study is to investigate the contributing effect of contrast media (CM) iodine dose on radiation-induced DNA damage in blood lymphocytes during a cardiac CT scan. <b>MATERIALS AND METHODS.</b> The minipigs were exposed 12 times in total to a fixed cardiac CT scan protocol. An unenha...
2,329,203
Which source and level of dietary sodium is appropriate for broiler chickens reared in a high-altitude area?
This study investigated effect of increasing level of dietary sodium using sodium bicarbonate or sodium chloride on growth performance, mortality, characteristics of carcass, organs and tibia, calcium and phosphorus of serum in broilers reared in a high-altitude area (1,700&#xa0;m above sea level). A total of 588 Ross ...
2,329,204
Two cases of penetrating left ventricular cardiac trauma: Pre-hospital ultrasound and direct to theatre.
Left ventricular (LV) Cardiac penetrating trauma is a rare and grave injury. In cases of penetrating cardiac trauma, pre-hospital Ultrasound by flight doctors can assist identify specific pathology. This pre-hospital triage has now been linked to a change in both pre-hospital and in-hospital management. There are minim...
2,329,205
Accurate assessment of LV function using the first automated 2D-border detection algorithm for small animals - evaluation and application to models of LV dysfunction.
Echocardiography is the most commonly applied technique for non-invasive assessment of cardiac function in small animals. Manual tracing of endocardial borders is time consuming and varies with operator experience. Therefore, we aimed to evaluate a novel automated two-dimensional software algorithm (Auto2DE) for small ...
2,329,206
Blood Pressure Profile, Catecholamine Phenotype, and Target Organ Damage in Pheochromocytoma/Paraganglioma.
Impaired diurnal blood pressure (BP) variability is related to higher cardiovascular risk.</AbstractText>To assess diurnal variability of BP and its relation to target organ damage (TOD) and catecholamine phenotype in a consecutive sample of pheochromocytoma/paraganglioma (PPGL).</AbstractText>We included 179 patients ...
2,329,207
Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease.
Plasma neurofilament light (NfL) has been suggested as a noninvasive biomarker to monitor neurodegeneration in Alzheimer disease (AD), but studies are lacking.</AbstractText>To examine whether longitudinal plasma NfL levels are associated with other hallmarks of AD.</AbstractText><AbstractText Label="DESIGN, SETTING, A...
2,329,208
Echinococcosis in left ventricle: a case report.
Echinococcosis, also called hydatid disease, is a common parasitic infection of the liver. However, echinococcus lesions rarely involve the heart, especially in children.</AbstractText>An 8-year-old child from grazing areas of northwest China was referred to our hospital for the complaint of inpersistent precordial che...
2,329,209
Neuronavigator-guided ventriculoscopic approach for symptomatic xanthogranuloma of the choroid plexus in the lateral ventricle.
Xanthogranuloma of choroid plexus is an extremely rare, benign, and mostly asymptomatic intracranial lesion. We report a case of symptomatic lateral ventricular xanthogranuloma resected via a neuronavigator-guided ventriculoscopic approach. Then we review recent English medical literature and notice that craniotomies h...
2,329,210
Optimization of CRT programming using non-invasive electrocardiographic imaging to assess the acute electrical effects of multipoint pacing.
Quadripolar lead technology and multi-point pacing (MPP) are important clinical adjuncts in cardiac resynchronization therapy (CRT) pacing aimed at reducing the rate of non-response to therapy. Mixed results have been achieved using MPP and it is critical to identify which patients require this approach and how to conf...
2,329,211
Low grade oligodendroglioma seeding around the 4th ventricle.
We report a 45 years old female patient with a left temporal grade II oligodendroglioma that recurred on the wall of the fourth ventricle at grade II oligodendroglioma.
2,329,212
Platelet microvesicles promote the recovery of neurological function in mouse model of cerebral infarction by inducing angiogenesis.
The aim of this study is to investigate the effect of PMVs on mice with ischemic cerebral infarction and its mechanism. Male C57BL/6 mice were selected, and the right focal cortical infarction model was established via cauterization under a microscope and randomly divided into sham operation (Sham) group, normal saline...
2,329,213
Fourth Ventricular Meningiomas.
Fourth ventricular meningiomas (FVMs) are extremely rare. Here, we report a series of 11 patients at a single institution. A comprehensive literature analysis is conducted.</AbstractText>Information about 11 patient was extracted from the patient data. Reports of cases in English were obtained from the literature. Incl...
2,329,214
Exendin-4 attenuates brain mitochondrial toxicity through PI3K/Akt-dependent pathway in amyloid beta (1-42)-induced cognitive deficit rats.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by memory loss, disorientation and gradual deterioration of intellectual ability. In the pharmacotherapy of AD, the mitochondrial protective activity of Exendin-4 in experimental studies is yet to be established though its effectiveness ...
2,329,215
Association of body mass index with cardiac resynchronization therapy intention and left ventricular lead implantation failure: insights from the NCDR implantable cardioverter-defibrillator registry.
Cardiac resynchronization therapy with defibrillator (CRT-D) implantation involves left ventricular (LV) lead placement for biventricular pacing and is more complex than implantable cardioverter-defibrillator (ICD)-only implantation. Differences in the prescription of CRT-D versus ICD may result from clinician biases b...
2,329,216
Neurological and neuropsychological outcome after resection of craniopharyngiomas.
Craniopharyngiomas are rare and benign tumors of the sellar and/or parasellar region. Primary treatment involves resection followed by adjuvant radiotherapy. While the grade of resection was frequently analyzed following surgery, the neurological outcome and especially neuropsychological deficits and quality of life ha...
2,329,217
Brain volumes and their ratios in Alzheimer&#xb4;s disease on magnetic resonance imaging segmented using Freesurfer 6.0.
Ratios between opposing volumes from brain magnetic resonance imaging (MRI) can provide additional information to volumes in Alzheimer's disease (AD). Brain three-dimensional MPRAGE MRI at 3T were segmented into 44 regions using FreeSurfer v6 in 75 participants. The region's size in absolute volumes and relative propor...
2,329,218
Pediatric meningiomas: a report of 5 cases and review of literature.
The purpose of this paper is to provide novel insight into the rare pediatric meningiomas.</AbstractText>We retrospectively analyzed pediatric surgical cases of meningioma during 2002 to 2017 in our institution. The preoperative, intraoperative, and the postoperative status were collected to find any unique features th...
2,329,219
Early signs of middle cerebral artery infarction on multidetector computed tomography: Review of 20 cases.
This study intended to assess the occurrence of early signs of middle cerebral artery (MCA) on multidetector computed tomography (MDCT) in correlation with duration of the clinical features of stroke.</AbstractText>This retrospective study analyzed the electronic records of 20 patients with MCA infarction. The detected...
2,329,220
Proliferation and Differentiation in the Adult Subventricular Zone Are Not Affected by CSF1R Inhibition.
Microglia are reported to have significant roles in regulating normal mammalian adult neurogenesis. There are two neurogenic niches in the adult mammal brain: the subgranular zone (SGZ) in the hippocampus, and the subventricular zone (SVZ), which makes up the lining of the lateral ventricles. While the microglia intera...
2,329,221
Sorted Golden-step phase encoding: an improved Golden-step imaging technique for cardiac and respiratory self-gated cine cardiovascular magnetic resonance imaging.
Numerous self-gated cardiac imaging techniques have been reported in the literature. Most can track either cardiac or respiratory motion, and many incur some overhead to imaging data acquisition. We previously described a Cartesian cine imaging technique, pseudo-projection motion tracking with golden-step phase encodin...
2,329,222
Reference ranges for the left ventricle modified myocardial performance index, respective time periods, and atrioventricular peak velocities between 20 and 36&#x2009;+&#x2009;6 weeks of gestation.
<b>Objective:</b> To establish reference ranges for the fetal left ventricle (LV) modified myocardial performance index (Mod-MPI), respective time periods, and right and left atrioventricular peak velocities between 20 and 36&#x2009;+&#x2009;6 weeks of gestation.<b>Methods:</b> This cross-sectional study evaluated 360 ...
2,329,223
Effects of Calorie Restriction and Voluntary Exercise on Doxorubicin-Induced Cardiotoxicity.
Doxorubicin (DOX) is a widely used chemotherapeutic agent with known cardiotoxic properties, while calorie restriction (CR) and exercise have well-documented cardioprotective effects. No studies have investigated the effects of CR alone or the combined effects of CR and exercise on DOX cardiotoxicity.</AbstractText>Rat...
2,329,224
Sister, Sister: Ependymal Cells and Adult Neural Stem Cells Are Separated at Birth by Geminin Family Members.
The adult subventricular zone (SVZ) stem cell niche is comprised of multi-ciliated ependymal cells that line the&#xa0;brain ventricular system and adult stem cells. Papers in Neuron (Ortiz-&#xc1;lvarez et&#xa0;al., 2019) and Cell Reports (Redmond et&#xa0;al., 2019) report that these cell types share a common precursor....
2,329,225
Pressure overload induced right ventricular remodeling is not attenuated by the anti-fibrotic agent pirfenidone.
Cardiac fibrosis contributes to the development of heart failure in pulmonary hypertension. We aimed to assess the development of fibrosis and the effects of treatment with the anti-fibrotic agent pirfenidone in pressure overload induced right ventricular (RV) failure. Wistar rat weanlings were randomized to pulmonary ...
2,329,226
Optimized cultivation of porcine choroid plexus epithelial cells, a blood-cerebrospinal fluid barrier model, for studying granulocyte transmigration.
The blood-cerebrospinal fluid barrier (BCSFB) plays important roles during the transport of substances into the brain, the pathogenesis of central nervous system (CNS) diseases, and neuro-immunological processes. Along these lines, transmigration of granulocytes across the blood-cerebrospinal fluid (CSF) barrier (BCSFB...
2,329,227
Visualizing flow in an intact CSF network using optical coherence tomography: implications for human congenital hydrocephalus.
Cerebrospinal fluid (CSF) flow in the brain ventricles is critical for brain development. Altered CSF flow dynamics have been implicated in congenital hydrocephalus (CH) characterized by the potentially lethal expansion of cerebral ventricles if not treated. CH is the most common neurosurgical indication in children ef...
2,329,228
Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction.
The primary cause of heart failure is the loss of cardiomyocytes in the diseased adult heart. Previously, we reported that the miR-17-92 cluster plays a key role in cardiomyocyte proliferation. Here, we report that expression of miR-19a/19b, members of the miR-17-92 cluster, is induced in heart failure patients. We sho...
2,329,229
Position and size of massa intermedia in Serbian brains.
Massa intermedia, a midline bar-shaped structure, connects two thalami across the third ventricle in 70-80% of healthy humans. It has become clinically important since its absence was comprehended as a midline malformation of the brain and brought in connection with schizophrenia indicating that some symptoms could be ...
2,329,230
Impact of left ventricular pacing threshold on ventricular arrhythmia occurrence in cardiac resynchronization therapy.
Cardiac resynchronization therapy (CRT) is an established heart failure (HF) treatment option, however its effect on ventricular arrhythmias (VAs) is controversial. Regional scar burden and high left ventricular (LV) pacing threshold (PT) are associated with poor outcome in CRT patients. The aim of our study was to ana...
2,329,231
Impaired hippocampal development and outcomes in very preterm infants with perinatal brain injury.
Preterm infants are at high risk for brain injury during the perinatal period. Intraventricular hemorrhage and periventricular leukomalacia, the two most common patterns of brain injury in prematurely-born children, are associated with poor neurodevelopmental outcomes. The hippocampus is known to be critical for learni...
2,329,232
Lipopolysaccharide-Binding Protein Is an Early Biomarker of Cardiac Function After Radiation Therapy for Breast Cancer.
To evaluate the prognostic potential of lipopolysaccharide-binding protein (LBP) levels after breast cancer radiation therapy (RT) for incipient cardiac dysfunction.</AbstractText>In this single-centered study, we prospectively enrolled female patients treated for left breast cancer. Healthy age- and sex-matched partic...
2,329,233
[Electrhopysiological Effect of the Polyamine Spermine in Normoxic and Ischemic Ventricular Myocardium].
Cytoplasmic polyamines (PA) are involved in control of many cellular functions and are well known as regulators of so called inward-rectifier&#xa0;potassium ion channels. Nevertheless, functional significance of extracellular PA in the heart is poorly elucidated. Aim of this study was&#xa0;to study effects of endogenou...
2,329,234
Chronic effects of platinum(IV) complex and its diamine ligand on rat heart function: comparison with cisplatin.
The aim of the present study was to compare the cardiodynamic parameters in the isolated rat heart in animals chronically treated with cisplatin, platinum(IV) complex and its diamine ligand. Sixty Wistar albino rats (8&#xa0;weeks old) were divided into five groups: three experimental and two control groups. Animals in ...
2,329,235
Usefulness of ultrasound in the management of acute respiratory distress syndrome.
Acute respiratory distress syndrome (ARDS) is a life-threatening disease. Different imaging techniques have been used to diagnose and guide the ventilatory management of patients with ARDS. Chest ultrasound is a reliable tool to identify interstitial syndrome, lung consolidation, lung collapse, and pleural effusion. In...
2,329,236
A viscoelastic adhesive epicardial patch for treating myocardial infarction.
Acellular epicardial patches that treat myocardial infarction by increasing the mechanical integrity of damaged left ventricular tissues exhibit widely scattered therapeutic efficacy. Here, we introduce a viscoelastic adhesive patch, made of an ionically crosslinked transparent hydrogel, that accommodates the cyclic de...
2,329,237
Different effects of prenatal MAM vs. perinatal THC exposure on regional cerebral blood perfusion detected by Arterial Spin Labelling MRI in rats.
Clinical studies consistently report structural impairments (i.e.: ventricular enlargement, decreased volume of anterior cingulate cortex or hippocampus) and functional abnormalities including changes in regional cerebral blood flow in individuals suffering from schizophrenia, which can be evaluated by magnetic resonan...
2,329,238
Cardiac Biomarkers and Cardiovascular Outcome in Children with Chronic Kidney Disease.
Myocardial dysfunction is a leading cause of mortality in chronic kidney disease (CKD) children specially those on regular hemodialysis. Cardiac biomarkers play a key role for early detection of myocardial injury. We aim to clarify the prognostic role of circulating cardiac biomarkers, heart type fatty acid binding pro...
2,329,239
Interstitial Adipocytes in the Beagle Dog and New Zealand White Rabbit Choroid Plexus.
The choroid plexus (CP) produces cerebrospinal fluid and has epithelial, interstitial, and vascular compartments. The CP is a potential site of toxicity, and recognizing the normal microanatomy in different animal models is important for the pathologist. In preclinical studies with beagle dog and New Zealand white rabb...
2,329,240
Evaluation of intracerebral ventricles volume of patients with Parkinson's disease using the atlas-based method: A methodological study.
Knowing the volumetric changes in brain can allow for the estimation of the disease progression of various neurodegenerative disorders. Many studies have been shown that the volumetric changes in the some brain structures especially including the dopaminergic neurons, in patients with Parkinson's disease (PD). The obje...
2,329,241
Incidence trends of adult malignant brain tumors in Finland, 1990-2016.
<b>Background:</b> Several studies have reported increased incidence trends of malignant gliomas in the late 1900s with a plateau in the 2000s, but also some recent increases have been reported. The purpose of our study was to analyze incidence trends of malignant gliomas in Finland by morphology and tumor location. <b...
2,329,242
An Intraventricular Type of Chondroma: A Case Report.
Intracranial chondromas are unusual benign tumors. They commonly occur at the base of the skull, whereas an intraventricular type is very rare. We present the case of a 19-year-old female patient with a giant intraventricular chondroma detected incidentally by imaging after a car accident. The spiral head CT scan and M...
2,329,243
Morphological classification of the moderator band and its relationship with the anterior papillary muscle.
This study investigated and classified the various types of moderator band (MB) in relation to the anterior papillary muscle, with the aim of providing anatomical reference information and fundamental knowledge for use when repairing the congenital defects and understanding the conduction system. The study investigated...
2,329,244
Short-term effects of sleeve gastrectomy on weight loss and diastolic function in obese patients.
diac structure and function in obese patients. This study was an examination of the short-term effects of sleeve gastrectomy on body measurements and diastolic function.</AbstractText>A total of 41 consecutive obese patients who were scheduled to undergo a sleeve gastrectomy procedure were included in the study. Baseli...
2,329,245
Right ventricular function after cardiac surgery: the diagnostic and prognostic role of echocardiography.
Cardiac surgical techniques and circulatory supports have strongly evolved in the last years. Right ventricular (RV) function during the post-operatory period is still subject of study, although its relevant prognostic impact has been variably described in different papers. RV post-surgical dysfunction's underlying mec...
2,329,246
CKLF1 Aggravates Focal Cerebral Ischemia Injury at Early Stage Partly by Modulating Microglia/Macrophage Toward M1 Polarization Through CCR4.
CKLF1 is a chemokine with increased expression in ischemic brain, and targeting CKLF1 has shown therapeutic effects in cerebral ischemia model. Microglia/macrophage polarization is a mechanism involved in poststroke injury expansion. Considering the quick and obvious response of CKLF1 and expeditious evolution of strok...
2,329,247
Schwalbe's Triangular Fossa: Normal and Pathologic Anatomy on Frozen Cadavers. Anatomo-Magnetic Resonance Imaging Comparison and Surgical Implications in Colloid Cyst Surgery.
The fornix is a region of greatest neurosurgical interest in regards to its complex anatomy and surgical approaches to this area. The objective of this study was to evaluate the morphology of the triangular recess (TR) and its role in the growth pattern of the colloid cysts (CC) within the third ventricle and in the ch...
2,329,248
Strap Muscle Type I Thyroplasty After Gore-Tex Implant Extrusion: Case Report and Literature Review.
To discuss the presentation and management techniques of implant extrusion following type I thyroplasty and to illustrate the potential of strap muscle for augmentation following implant removal.</AbstractText>We report a unique case of a patient with late Gore-Tex implant extrusion after type I thyroplasty treated wit...
2,329,249
Endoscopic Transanterior Middle Temporal Approach to the Atrium-An Anatomical Feasibility Study.
The atrium is the most common location for masses in the lateral ventricle. However, access to this area is limited owing to its deep location and adjacent eloquent neurovascular structures, such as the choroidal arteries, perisylvian white matter (WM) tracts, and optic radiations. We investigated the feasibility and s...
2,329,250
Hepatocellular carcinoma diagnosed in a patient who had Fontan operation 30 years ago: a case report.
The Fontan operation is performed in patients with a single ventricle. As the systemic venous return is directly connected to the pulmonary circulation during this procedure, chronic hepatic congestion is induced, leading to Fontan-associated liver disease (FALD) including liver cirrhosis and hepatocellular carcinoma (...
2,329,251
Left Atrial-Veno-Arterial Extracorporeal Membrane Oxygenation: Step-By-Step Procedure and Case Example.
Veno-arterial extracorporeal membrane oxygenation is used in patients requiring biventricular support; however, its use increases the afterload. In patients with severe aortic insufficiency or severe left ventricular disfunction, it will increase left-side filling pressures, hence the need for left ventricle unloading ...
2,329,252
Synchronous Bilateral Laryngeal Oncocytic Papillary Cystadenoma: An Uncommon Occurrence.
Oncocytic papillary cystadenoma is a rare, benign tumor highly uncommon in the larynx. Although controversy exists regarding its true nature it is considered a phenomenon of metaplasia. We present the case of a 57-year-old patient with synchronous, bilateral oncocytic papillary cystadenoma of the ventricles and we disc...
2,329,253
Endoscopic Endonasal Approach to the Third Ventricle Using the Surgical Corridor of the Reverse Third Ventriculostomy: Anatomo-Surgical Nuances.
<b>Objective</b> &#x2003;Surgical access to the third ventricle can be achieved through various corridors depending on the location and extent of the lesion; however, traditional transcranial approaches risk damage to multiple critical neural structures. <b>Methods</b> &#x2003;Endonasal approach similar to corridor of ...
2,329,254
Revisiting Folger's pouch in double-chambered right ventricle.
Folger's pouch is a right ventricular outflow pouch arising from the distal low-pressure chamber in double-chambered right ventricle. It is rarely described on echocardiogram due to difficult visualization and lack of knowledge of its existence. Retrospective assessment of echocardiogram after an angiocardiographic eva...
2,329,255
First Report of Massive Myocardial Calcifications in a Vervet Monkey (<i>Chlorocebus pygerythrus</i>).
A 13-years-old male vervet monkey that was kept in a primates breeding and research facility at Razi Vaccine and Serum Research Institute, Karaj, Iran (RVSRI) died suddenly. Massively scattered grayish-yellow mottling on both ventricles were the most significant gross necropsy findings. There was a gritty feeling on pa...
2,329,256
How I do it: Novel technique to "Unmask" and treat congenital portosystemic venous connections in congenital heart disease.
Congenital portosystemic venous connections are rare vascular anomalies that connect the portal and systemic venous circulations. These vascular lesions can lead to complex and varied physiologic manifestations in single-ventricle patients as they progress through the various stages of palliation in the Fontan pathway....
2,329,257
Rodent models of senile normal-pressure hydrocephalus.
Cerebrospinal fluid (CSF) and its drainage are crucial in clearing metabolic waste and maintaining the microenvironment of the central nervous system for proper functioning. Normal-pressure hydrocephalus (NPH) is a serious neurological disorder of the elderly with obstruction of CSF flow outside the cerebral ventricles...
2,329,258
Oncocytic Papillary Cystadenoma, an Unusual Variant Presenting as a Laryngeal Ventricular Cyst.
Cystadenoma arising from the larynx is a rare benign minor salivary gland tumor that can show mucinous or papillary morphology. The epithelial lining of the salivary gland tumor can present with oncocytic features, which is attributed to an increased number of mitochondria. We present a rare case of oncocytic papillary...
2,329,259
Interventricular-Septal Output While Supported on Left Ventricular Assist Device Therapy.<Pagination><StartPage>424</StartPage><EndPage>428</EndPage><MedlinePgn>424-428</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1097/MAT.0000000000001851</ELocationID><Abstract><AbstractText>The effects of left v...
The effects of left ventricular unloading on septal function in patients with left ventricular assist devices (LVADs) have not been well characterized in vivo. The purpose of this study was to evaluate the relationship between markers of septal function with echocardiography in relationship to RV dysfunction and late R...
2,329,260
[Hydrocephalus in children: clinical, paraclinical and therapeutic features in four medical facilities in Lubumbashi].
hydrocephalus is a progressive distension of the anatomical spaces (ventricles and subarachnoid space) containing the cerebrospinal fluid. It most commonly affects children. In developed countries, its prevalence and incidence are estimated between 0.9 to 1.2 per 1000 and 0.2 to 0.6 per 1000 live births respectively an...
2,329,261
A Low-Molecular-Weight BDNF Mimetic, Dipeptide GSB-214, Prevents Memory Impairment in Rat Models of Alzheimer's Disease.
Brain-derived neurotrophic factor (BDNF) is known to be involved in the pathogenesis of Alzheimer's disease (AD). However, the pharmacological use of full-length neurotrophin is limited, because of its macromolecular protein nature. A dimeric dipeptide mimetic of the BDNF loop 1, bis-(N-monosuccinyl-L-methionyl-L-serin...
2,329,262
Clinical prognostic factors for central neurocytoma and subgroup analysis of different treatment measures: A SEER database-based retrospective analysis from 2003 to 2019.
The study aimed to identify clinical prognostic factors affecting overall survival (OS) in patients with central neurocytoma (CN) and to determine independent prognostic factors in the subgroups of different treatment modalities using a retrospective analysis based on the SEER database from 2003 to 2019.</AbstractText>...
2,329,263
Ontogeny of ependymoglial cells lining the third ventricle in mice.
During hypothalamic development, the germinative neuroepithelium gives birth to diverse neural cells that regulate numerous physiological functions in adulthood.</AbstractText>Here, we studied the ontogeny of ependymal cells in the mouse mediobasal hypothalamus using the BrdU approach and publicly available single-cell...
2,329,264
Effects of RFRP&#x2011;3 on an ovariectomized estrogen&#x2011;primed rat model and HEC&#x2011;1A human endometrial carcinoma cells.
The hypothalamic peptide gonadotropin inhibitory hormone (GnIH) is a relatively novel hypothalamic neuropeptide, identified in 2000. It can influence the hypothalamic-pituitary-gonadal axis and reproductive function through various neuroendocrine systems. The present study aimed to explore the effects and potential und...
2,329,265
Impact of aging on mitochondrial respiration in various organs.
Mitochondria are considered central regulator of the aging process; however, majority of studies dealing with the impact of age on mitochondrial oxygen consumption focused on skeletal muscle concluding (although not uniformly) a general declining trend with advancing age. In addition, gender related differences in mito...
2,329,266
Preliminary Experience Suggests the Addition of Choroid Plexus Cauterization to Functional Hemispherectomy May Reduce Posthemispherectomy Hydrocephalus.
Cerebral hemispherectomy can effectively treat unihemispheric epilepsy. However, posthemispherectomy hydrocephalus (PHH), a serious life-long complication, remains prevalent, requiring careful considerations in technique selection and postoperative management. In 2016, we began incorporating open choroid plexus cauteri...
2,329,267
Transitional vascular anomaly of a persistent medial procephalic vein causing obstructive hydrocephalus and intracranial haemorrhage.
We report a case of obstructive hydrocephalus caused by a transitional (shunting) developmental venous anomaly not previously reported in the literature. Both thalami in this patient drain into a midline vein in the floor of the third ventricle that crosses the cerebral aqueduct and exerts mass effect. While this patie...
2,329,268
Linear Energy Transfer and Relative Biological Effectiveness Investigation of Various Structures for a Cohort of Proton Patients With Brain Tumors.
The current knowledge on biological effects associated with proton therapy is limited. Therefore, we investigated the distributions of dose, dose-averaged linear energy transfer (LETd</sub>), and the product between dose and LETd</sub> (DLETd</sub>) for a patient cohort treated with proton therapy. Different treatment ...
2,329,269
High cardiomyocyte diversity in human early prenatal heart development.<Pagination><StartPage>105857</StartPage><MedlinePgn>105857</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">105857</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.isci.2022.105857</ELocationID><Abstract><AbstractText>Ca...
Cardiomyocytes play key roles during cardiogenesis, but have poorly understood features, especially in prenatal stages. Here, we characterized human prenatal cardiomyocytes, 6.5-7&#xa0;weeks post-conception, by integrating single-cell RNA sequencing, spatial transcriptomics, and ligand-receptor interaction information....
2,329,270
Anomalous coronary artery connecting left and right coronaries crossing right ventricular outflow tract in Hoffman variant tetralogy of Fallot.<ELocationID EIdType="pii" ValidYN="Y">ezac592</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1093/ejcts/ezac592</ELocationID><AuthorList CompleteYN="Y"><Author ValidYN=...
The choroid plexus (CP), a highly vascularized structure protruding into the ventricles of the brain, is one of the most understudied tissues in neuroscience. As it is becoming increasingly clear that this tiny structure plays a crucial role in health and disease of the central nervous system (CNS), it is of utmost imp...
2,329,271
Can a Cerebral Congenital Anomaly Present in Adulthood?
Colpocephaly, a congenital anomaly in the ventricles, is usually discovered early in infancy and rarely during adulthood. Partial or complete agenesis of the corpus callosum or Chiari malformations (developmental arrest of white matter formation in early fetal development) can lead to abnormal asymmetrical ventricular ...
2,329,272
Pre- and Postnatal Characterization of Autosomal Recessive <i>KIDINS220</i>-Associated Ventriculomegaly.
Heterozygous loss-of-function variants in the last 2 exons of KIDINS220</i> have been associated with spastic paraplegia, intellectual disability, nystagmus, and obesity (SINO). Syndromic features of this condition include macrocephaly and dilatation of the lateral ventricles. Homozygous variants in the more proximal e...
2,329,273
Predicted cardiac and second cancer risks for patients undergoing VMAT for mediastinal Hodgkin lymphoma.<Pagination><StartPage>1368</StartPage><EndPage>1377</EndPage><MedlinePgn>1368-1377</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s12094-022-03034-z</ELocationID><Abstract><AbstractText Labe...
To predict treatment-related cardiovascular disease (CVD) and second cancer 30-year absolute mortality risks (AMR30</sub>) for patients with mediastinal Hodgkin lymphoma in a large multicentre radiation oncology network in Ireland.</AbstractText>This study includes consecutive patients treated for mediastinal lymphoma ...
2,329,274
Impact of spraying eggs with betaine after exposure to short-term thermal stress during early embryogenesis on pre and post-hatch performance of Japanese quail.
It is essential to understand and manage environmental factors for good quail production and welfare. One of the most important environmental stressors that hinder quail productivity is heat stress. This study aimed to evaluate the impact of spraying Japanese quail (Coturnix coturnix japonica) eggs with betaine after e...
2,329,275
Non-typeable Haemophilus influenza ventriculitis, a case report and literature review.
and importance: Haemophilus influenza severe presentations have decreased dramatically after the Hib vaccination was introduced. However, due to the emergence of Multi-drug resistance organisms, severe presentations like meningitis and ventriculitis may occur.</AbstractText>Here, we have described a rarely reported cas...
2,329,276
Outcomes of Cardiac Gunshot Injuries Presenting at an Urban Trauma Facility in Johannesburg, South Africa.
Gunshot wounds to the heart are regarded as one of the most lethal penetrating injuries. There has been an increase in gunshot wounds to the chest in our institution in recent years. Injuries to the heart caused by gunshot wounds can be challenging, with patients arriving in hospital in different physiological states. ...
2,329,277
Takotsubo cardiomyopathy following liver transplantation and COVID-19 infection.<Pagination><StartPage>99</StartPage><EndPage>100</EndPage><MedlinePgn>99-100</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1080/08998280.2022.2114069</ELocationID><Abstract><AbstractText>Takotsubo cardiomyopathy involv...
Takotsubo cardiomyopathy involves transient systolic dysfunction of the left ventricle thought to be caused by a physiologic stress response and associated catecholamine release. We present a previously undocumented cause of this stress response involving a 53-year-old man with hepatocellular carcinoma and alcohol-asso...
2,329,278
Intraoperative Ventricular Opening has No Effect on Complication Development Following BCNU Wafer Implantation for Malignant Glioma.
To evaluate the safety profile of bis-chloroethyl-nitrosourea (BCNU) wafer implantation after malignant glioma resection with or without ventricular opening (VO).</AbstractText>This single-center retrospective study included 66 consecutive patients with BCNU wafer implantation after malignant glioma resection between M...
2,329,279
Impella Support for Surgical Ventricular Septal Defect Repair.<Pagination><StartPage>e278</StartPage><EndPage>e283</EndPage><MedlinePgn>e278-e283</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1097/MAT.0000000000001873</ELocationID><Abstract><AbstractText>Acute postinfarct ventricular septal defect ...
Acute postinfarct ventricular septal defect (VSD) is associated with high mortality due to a combination of cardiogenic shock and a complex repair in recently infarcted fragile myocardium. 1 Although the Impella heart pump is established as support for cardiogenic shock, it is relatively contraindicated in postinfarct ...
2,329,280
Left ventricular aneurysm: Truths and falsehoods.<Pagination><StartPage>308</StartPage><EndPage>309</EndPage><MedlinePgn>308-309</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.33963/KP.a2022.0293</ELocationID><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zio&#x142;o</LastName><ForeName>Je...
Right ventricular clot-in-transit (CIT) is a rare finding in venous thromboembolic disease and carries a high mortality rate. Its optimal treatments have yet to be established in the literature. Here we describe the usage of a suction-based catheter, the INARI FlowTriever&#xae; system (INARI Medical Inc.) to successful...
2,329,281
Lateral Horizontal Head Position Approach for the Lateral and Anterior Third Ventricles: A Subependymoma Clinical Case and Literature Review.
Subependymomas are benign, slow-growing, noninvasive solitary lesions of World Health Organization Grade I cerebral ependymal origin that are rare compared with other types of ependymomas. Anterior third ventricle subependymomas are usually detected during autopsies in cases of sudden death due to acute or intermittent...
2,329,282
The Prevalence, Location, and Dimensions Of Interthalamic Adhesions and Their Clinical Significance: Corpse Brain Analysis.
<b>Background</b> &#x2003;Interthalamic adhesion (ITA) or massa intermedia is a midline rod-like neural structure interconnecting the medial surfaces of two thalami. Its absence is considered as a midline defect associated with schizophrenia spectrum disorder. The present study aimed to determine the prevalence, locati...
2,329,283
Erythropoietin administration exerted neuroprotective effects against cardiac ischemia/reperfusion injury.<Pagination><StartPage>100124</StartPage><MedlinePgn>100124</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">100124</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.crphar.2022.100124</E...
Acute myocardial infarction (AMI) leads to cardiac dysfunction and also causes brain dysfunction and pathology. The neuroprotective effects of erythropoietin (EPO), the hormone controlling the production of red blood cells, have been shown in case of cerebral ischemic/reperfusion (I/R) injury. However, the effects of E...
2,329,284
Ultrasonic Diagnosis and Management of Posthemorrhagic Ventricular Dilatation in Premature Infants: A Narrative Review.
The survival rate of preterm infants is increasing as a result of technological advances. The incidence of intraventricular hemorrhages (IVH) in preterm infants ranges from 25% to 30%, of which 30% to 50% are severe IVH (Volpe III-IV, Volpe III is defined as intraventricular bleeding occupying more than 50% of the vent...
2,329,285
Thiocyanate Reduces Motor Impairment in the hMPO-A53T PD Mouse Model While Reducing MPO-Oxidation of Alpha Synuclein in Enlarged LYVE1/AQP4 Positive Periventricular Glymphatic Vessels.
Parkinson's disease (PD) is due to the oxidation of alpha synuclein (&#x3b1;Syn) contributing to motor impairment. We developed a transgenic mouse model of PD that overexpresses the mutated human &#x3b1;Syn gene (A53T) crossed to a mouse expressing the human MPO gene. This model exhibits increased oxidation and chlorin...
2,329,286
Disseminated Human Subarachnoid Coenurosis.
Background: Traditionally, human coenurosis has been ascribed to Taenia multiceps while neurocysticercosis has been attributed solely to Taenia solium infection. Historically, however, the identification and differentiation of cestodal infection was primarily based on inaccurate morphological criteria. With the increas...
2,329,287
Localization of TRPV3/4 and PIEZO1/2 sensory receptors in murine and human larynges.<Pagination><StartPage>1963</StartPage><EndPage>1972</EndPage><MedlinePgn>1963-1972</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/lio2.968</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="UNA...
Heart failure (HF) is a complex clinical syndrome that results from either functional or structural impairment of ventricles resulting in symptomatic left ventricle (LV) dysfunction. The symptoms&#xa0;come from an inadequate cardiac output, failing to keep up with the metabolic demands of the body. It is a leading caus...
2,329,288
Understanding the Role of the Choroid Plexus in Multiple Sclerosis as an MRI Biomarker of Disease Activity.<Pagination><StartPage>405</StartPage><EndPage>406</EndPage><MedlinePgn>405-406</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1212/WNL.0000000000206806</ELocationID><AuthorList CompleteYN="Y">...
Heart failure with preserved ejection fraction (HFpEF) is often complicated by pulmonary hypertension (PH), which is mainly characterised by postcapillary PH and occasionally accompanied by a precapillary component of PH. Haemodynamic changes in worsening heart failure (HF) can modify the characteristics of PH. However...
2,329,289
TRPV1 and GABA<sub>B1</sub> in the Cerebrospinal Fluid-Contacting Nucleus are Jointly Involved in Chronic Inflammatory Pain in Rats.
To assess the receptors of TRPV1 and GABAB1</sub> receptors that were colocalized in cerebrospinal fluid contacting nucleus (CSF-contact nucleus) of chronic inflammatory pain (CIP) rats bringing inspiration for reducing chronic pain.</AbstractText>A rat model of CIP was constructed by plantar injection of complete Freu...
2,329,290
Prognostic value of feature-tracking right ventricular longitudinal strain in heart transplant recipients.<Pagination><StartPage>3878</StartPage><EndPage>3888</EndPage><MedlinePgn>3878-3888</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s00330-022-09327-9</ELocationID><Abstract><AbstractText La...
The prognostic value of cardiac magnetic resonance feature tracking (CMR-FT)-derived right ventricular longitudinal strain (RVLS) post-heart transplantation has not been studied. This study aimed to evaluate the prognostic significance of CMR-FT-derived RVLS, in patients post- heart transplantation and to directly comp...
2,329,291
Delineation of intermammillary relationships using magnetic resonance imaging.<Pagination><StartPage>29</StartPage><EndPage>34</EndPage><MedlinePgn>29-34</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s00276-022-03063-x</ELocationID><Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE...
No study has investigated intermammillary relationships using neuroimaging modalities. This study aimed to explore them using magnetic resonance imaging (MRI).</AbstractText>We enrolled 72 patients who underwent conventional MRI examinations, followed by constructive interference steady-state sequence in the coronal pl...
2,329,292
[Metallic foreign bodies of brain ventricles].
Head injuries are often associated with intracranial foreign bodies that require decision making on the need for certain surgical treatment. Intraventricular foreign bodies are rare, so the question of surgical tactics is still open.</AbstractText>To summarize the experience of treating the wounded with intraventricula...
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Cat-Ear-Line: A Sonographic Sign of Cortical Development?<Pagination><StartPage>1445</StartPage><EndPage>1457</EndPage><MedlinePgn>1445-1457</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/jum.16153</ELocationID><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">Diagonal echogeni...
Diagonal echogenic lines outside the lateral ventricle have often been observed in the anterior coronal planes of the normal fetal brain by neurosonography. We have observed abnormal shapes of these echogenic lines in cases of malformation of cortical development (MCD). We named the ultrasound finding "cat-ear-line" (C...
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Case report: Active clinical manifestation of endocardial fibroelastosis in adolescence in a patient with mitral and aortic obstruction-histologic presence of endothelial-to-mesenchymal transformation.
This is the first description of active clinical manifestation of endocardial fibroelastosis (EFE) and remodeling of the endocardium <i>via</i> endothelial-to-mesenchymal transformation (EndMT) in an adolescent with Shone's variant hypoplastic left heart complex (HLHC) and a genetic heterozygous ABL1 variant. While EFE...
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Development of the brain ventricular system from a comparative perspective.
The brain ventricular system (BVS) consists of brain ventricles and channels filled with cerebrospinal fluid (CSF). Disturbance of CSF flow has been linked to scoliosis and neurodegenerative diseases, including hydrocephalus. This could be due to defects of CSF production by the choroid plexus or impaired CSF movement ...
2,329,296
A Randomized Trial of an Exclusive Human Milk Diet in Neonates with Single Ventricle Physiology.
To determine whether weight gain velocity (g/kg/day) 30&#xa0;days after the initiation of feeds after cardiac surgery and other clinical outcomes improve in infants with single ventricle physiology fed an exclusive human milk diet compared with a mixed human and bovine diet.</AbstractText>In this multicenter, randomize...
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What has single-cell transcriptomics taught us about long non-coding RNAs in the ventricular-subventricular zone?
Long non-coding RNA (lncRNA) function is mediated by the process of transcription or through transcript-dependent associations with proteins or nucleic acids to control gene regulatory networks. Many lncRNAs are transcribed in the ventricular-subventricular zone (V-SVZ), a postnatal neural stem cell niche. lncRNAs in t...
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Added value of hemodynamic forces for left ventricle function evaluation.<Pagination><StartPage>104409</StartPage><MedlinePgn>104409</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">104409</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ebiom.2022.104409</ELocationID><ELocationID EIdType="p...
The EXTRACT-PE trial evaluated the safety and performance of the Indigo Aspiration System (Penumbra&#xa0;Inc.) with an 8F continuous mechanical aspiration thrombectomy system for the treatment of pulmonary embolism (PE). This subgroup analysis evaluates performance outcomes of patients with main pulmonary artery (PA) e...
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Activin A rescues preterm brain injury through a novel Noggin/BMP4/Id2 signaling pathway.
Activin A (Act A) has been reported to promote oligodendrocyte progenitor cell (OPC) differentiation in&#xa0;vitro and improve neurological outcomes in adult mice. However, the roles and mechanisms of action of Act A in preterm brain injury are unknown. In the present study, P5 rats were subjected to hypoxia&#x2011;isc...