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2,329,400 | The Course and Neonatal Outcome of Choroid Plexus Extension to the Anterior Horn at the Routine Anatomy Scan. | Our objective was to examine the pregnancy course and immediate neonatal outcome of fetuses with an isolated extension of choroid plexus (CP) to the anterior horn during the second trimester.</AbstractText>We prospectively collected the cases referred to us between July 2012 and January 2021 with isolated finding of CP... |
2,329,401 | Hypothalamic insulin expression remains unaltered after short-term fasting in female rats. | Our previous study showed that 6-h fasting increased insulin expression in the hypothalamus of male rats. We, therefore, wanted to examine if this phenomenon occurs in female rats and whether it depended on the estrus cycle phase.</AbstractText>Female rats in proestrus or diestrus were either exposed to 6-h fasting or ... |
2,329,402 | Nicotinamide Mononucleotide Adenylyl Transferase 2 Inhibition Aggravates Neurological Damage after Traumatic Brain Injury in a Rat Model. | Nicotinamide mononucleotide adenylyl transferase 2 (NMNAT2) is a crucial factor for the survival of neuron. The role of NMNAT2 in damage following traumatic brain injury (TBI) remains unknown. This study was designed to investigate the role of NMNAT2 in TBI-induced neuronal degeneration and neurological deficits in rat... |
2,329,403 | An Unusual Case of Malignant Melanoma with Metastasis to the Placenta During Pregnancy. | We describe an unusual case of metastatic melanoma of the brain with an unknown primary site during pregnancy.</AbstractText>A 35-year-old woman in the third trimester of pregnancy presented with ataxia, nausea, vomiting, headaches and diplopia. CT of the brain revealed a hyper-attenuating 2.1 cm mass in the fourth ven... |
2,329,404 | Partial Obstruction of Ventricular Catheters Affects Performance in a New Catheter Obstruction Model of Hydrocephalus. | One of the major causes of cerebral ventricular shunt failure is proximal catheter occlusion. We describe a novel ventricular cerebrospinal fluid (CSF) flow replicating system that assesses pressure and flow responses to varying degrees of catheter occlusion.</AbstractText>Ventricular catheter performance was assessed ... |
2,329,405 | Vitamin C Deficiency Reduces Neurogenesis and Proliferation in the SVZ and Lateral Ventricle Extensions of the Young Guinea Pig Brain. | Although scurvy, the severe form of vitamin C deficiency, has been almost eradicated, the prevalence of subclinical vitamin C deficiency is much higher than previously estimated and its impact on human health might not be fully understood. Vitamin C is an essential molecule, especially in the central nervous system whe... |
2,329,406 | Meridianins Inhibit GSK3β In Vivo and Improve Behavioral Alterations Induced by Chronic Stress. | Major depression disorder (MDD) is a severe mental alteration with a multifactorial origin, and chronic stress is one of the most relevant environmental risk factors associated with MDD. Although there exist some therapeutical options, 30% of patients are still resistant to any type of treatment. GSK3β inhibitors... |
2,329,407 | Extraventricular site indicates higher grade but better prognosis in adult supratentorial ependymomas: a 14-year single-center retrospective cohort. | Supratentorial extraventricular ependymoma (STEE) and supratentorial intraventricular ependymoma (STIE) are two subsets of supratentorial ependymoma (SE). These two subsets have similar gene features and only differ in original sites: STEE occurs in the brain parenchyma, and STIE is located in ventricles and surrounded... |
2,329,408 | Longitudinal in Utero Analysis of Engrailed-1 Knockout Mouse Embryonic Phenotypes Using High-Frequency Ultrasound. | Large-scale international efforts to generate and analyze loss-of-function mutations in each of the approximately 20,000 protein-encoding gene mutations are ongoing using the "knockout" mouse as a model organism. Because one-third of gene knockouts are expected to result in embryonic lethality, it is important to devel... |
2,329,409 | Mortality and complications 1 year after treatment of hydrocephalus with endoscopic third ventriculostomy and ventriculoperitoneal shunt in children at Queen Elizabeth Central Hospital, Malawi. | Over the past two decades, the management of hydrocephalus has witnessed the addition of endoscopic third ventriculostomy with or without choroid plexus cauterization (ETV ± CPC) to the traditional methods including ventriculoperitoneal shunt insertion (VPSI). We conducted this study to assess mortal... |
2,329,410 | Favine/CCDC3 deficiency accelerated atherosclerosis and thrombus formation is associated with decreased MEF2C-KLF2 pathway. | Currently, no mouse models manifest calcification and thrombus formation, which is frequently associated with human atherosclerosis. We demonstrated that lack of Favine/CCDC3 in apoE knockout mice accelerated atherosclerosis accompanied by large cholesterol crystals and calcification, and also promoted thrombus formati... |
2,329,411 | Amylin regulates testosterone levels via steroidogenesis-related enzymes in the central nervous system of male mice. | Amylin is a peripheral satiation signal polypeptide co-secreted with insulin by pancreatic β-cells in response to nutrient ingestion. Amylin participates in the eating-inhibitory effect and regulates energy metabolism by acting on the central nervous system (CNS). However, the role of amylin in regulating the bio... |
2,329,412 | Glial functions in the blood-brain communication at the circumventricular organs. | The circumventricular organs (CVOs) are located around the brain ventricles, lack a blood-brain barrier (BBB) and sense blood-derived molecules. This review discusses recent advances in the importance of CVO functions, especially glial cells transferring periphery inflammation signals to the brain. The CVOs show size-l... |
2,329,413 | Case report: Atypical teratoid/rhabdoid tumor of the lateral ventricle in a male adolescent (case-based review and diagnostic challenges in developing countries). | Atypical teratoid/rhabdoid tumor (AT/RT) is a rare and highly malignant central nervous system (CNS) embryonal neoplasm: it accounts for <2% of all pediatric CNS tumors and occurs mainly in infants and young children. The primary site of this tumor is usually the posterior cranial fossa. Supratentorial and, in detai... |
2,329,414 | How much can AI see in early pregnancy: A multi-center study of fetus head characterization in week 10-14 in ultrasound using deep learning.<Pagination><StartPage>107170</StartPage><MedlinePgn>107170</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.cmpb.2022.107170</ELocationID><ELocationID EId... | To investigate if artificial intelligence can identify fetus intracranial structures in pregnancy week 11-14; to provide an automated method of standard and non-standard sagittal view classification in obstetric ultrasound examination METHOD AND MATERIALS: We proposed a newly designed scheme based on deep learning (DL)... |
2,329,415 | Protective effect of N-acetyl cysteine on the mitochondrial dynamic imbalance in temporal lobe epilepsy: Possible role of mTOR. | Understanding the underlying molecular mechanisms involved in epilepsy is critical for the development of more effective therapies. It is believed that mTOR (Mechanistic Target of Rapamycin kinases) activity and the mitochondrial dynamic balance change during epilepsy. mTOR affects mitochondrial fission by stimulating ... |
2,329,416 | Treatment with 1,25-Dihydroxyvitamin D3 Delays Choroid Plexus Infiltration and BCSFB Injury in MRL/lpr Mice Coinciding with Activation of the PPARγ/NF-κB/TNF-α Pathway and Suppression of TGF-β/Smad Signaling. | Neuropsychiatric systemic lupus erythematosus (NPSLE) is a serious complication of systemic lupus erythematosus (SLE) involving the nervous system with high morbidity and mortality. A key hypothesis in NPSLE is that a disrupted barrier allows autoantibodies and immune components of peripheral blood to penetrate into th... |
2,329,417 | The assessment of fetal cardiac output in maternal hypothyroidism under levothyroxine treatment.<Pagination><StartPage>1434</StartPage><EndPage>1438</EndPage><MedlinePgn>1434-1438</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/echo.15474</ELocationID><Abstract><AbstractText Label="OBJECTIVE">In... | In this study, we investigated whether maternal hypothyroidism has a role in the cardiac output (CO) of the fetus or not.</AbstractText>Pregnant women between 33 and 37 gestational weeks known to have hypothyroidism and using levothyroxine were accepted as the case group. Gestational age-matched healthy euthyroid pregn... |
2,329,418 | Update Reference Charts: Fetal Biometry between the 15th and 42nd Week of Gestation. | This study was designed to establish new reference charts for BPD (biparietal diameter), OFD (occipitofrontal diameter), HC (head circumference), CM (cisterna magna), TCD (transverse cerebellar diameter), PCV (posterior cerebral ventricle), AC (abdominal circumference), FL (femur length), and HL (humerus length) and ex... |
2,329,419 | Disease characteristics and patterns of familial colloid cyst of the third ventricle: An international survey of the Colloid Cyst Survivors Group. | Colloid cysts of the third ventricle are rare benign tumors, accounting for approximately 1% of all intracranial tumors. Familial colloid cysts are less common, only 25 cases have been previously reported in the literature. We aim to describe demographic and disease-specific characteristics to reduce the knowledge gap ... |
2,329,420 | Ventriculorenal shunts in the treatment of pediatric and adult hydrocephalus-historical perspective and analysis of current practice. | Hydrocephalus is a complex pathology that can have a significant impact on the quality of life in all age groups. Cerebrospinal fluid (CSF) diversions from the lateral ventricle to the peritoneal cavity are regarded as the treatment of first intent, but they have a high revision rate, and there are multiple factors whi... |
2,329,421 | Cardiac-derived extracellular matrix: A decellularization protocol for heart regeneration.<Pagination><StartPage>e0276224</StartPage><MedlinePgn>e0276224</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">e0276224</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pone.0276224</ELocationID... | Extracellular matrix (ECM) is a fundamental component of the heart, guiding vital cellular processes during organ homeostasis. Most cardiovascular diseases lead to a remarkable remodeling of the ECM, accompanied by the formation of a fibrotic tissue that heavily compromises the heart function. Effective therapies for m... |
2,329,422 | Positive Predictive Value of Endoscopic Findings to Diagnose Vocal Fold Paresis. | Laryngoscopy corresponding with laryngeal electromyography (LEMG) is essential in diagnosing vocal fold paresis. However, baseline asymmetry or other diseases oftentimes confound the exam, making diagnosis difficult. There is currently no agreed upon endoscopic criteria proven to reliably correlate with LEMG findings. ... |
2,329,423 | Endoscopic third ventricolustomy as treatment option for normal pressure hydrocephalus. | This descriptive cross-sectional study was performed on 24 patients with normal pressure hydrocephalus who underwent endoscopic third ventriculostomy. The patients were selected by the available sampling method, and the data was collected through a researcher-made checklist. Data were analyzed using SPSS-26 software. A... |
2,329,424 | Ectopic foci do not co-locate with ventricular epicardial stretch during early acute regional ischemia in isolated pig hearts.<Pagination><StartPage>e15492</StartPage><MedlinePgn>e15492</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">e15492</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.148... | Ectopic activation during early acute regional ischemia may initiate fatal reentrant arrhythmias. However, the origin of this ectopy remains poorly understood. Studies suggest that systolic stretch arising from dyskinesia in ischemic tissue may cause ectopic depolarization due to cardiac mechanosensitivity. The aim of ... |
2,329,425 | Upfront Radiosurgery for Treatment of Symptomatic Obstructive Hydrocephalus due to Brain Tumors. | Introduction Hydrocephalus is a build-up of cerebrospinal fluid (CSF) in the brain and is characterized by abnormal dilatation of the cerebral ventricles. Patients can be either asymptomatic, have symptoms related to primary tumors, or have hydrocephalus-related symptoms. Generally, symptomatic patients are candidates ... |
2,329,426 | Novelty in Impact of Neurorehabilitation in a Classic Case of Syringomyelia. | A fluid-filled hole inside the parenchyma or central canal of the spinal cord causes syringomyelia, a neurological condition. It is most frequently linked to type 1 Chiari malformations. Syringomyelia can be caused by tumors in the spinal cord, trauma, and post-traumatic or infectious adhesive arachnoiditis. Syringomye... |
2,329,427 | Creation of a novel course for the advanced emergency medicine ultrasound focused practice designation examination. | The American Board of Emergency Medicine recently established a new certification pathway in advanced emergency medicine ultrasound (AEMUS). Eligible applicants come from a wide range of experience but must pass the same examination to become certified. This study sought to evaluate a novel review course targeting a wi... |
2,329,428 | A Case of Non-Germinomatous Germ Cell Tumors of the Frontal Lobe Arising From the Lateral Ventricle With a Synchronous Pineal Lesion. | Non-germinomatous germ cell tumours (NGGCT) are rare intracranial tumours that account for 1% to 3% of cases. They are usually seen in the pineal and suprasellar regions. NGGCT of the frontal lobe arising from the lateral ventricle with a synchronous pineal lesion is uncommon. We present a case of NGGCT with multifocal... |
2,329,429 | Harmonization of Multi-Center Diffusion Tensor Tractography in Neonates with Congenital Heart Disease: Optimizing Post-Processing and Application of ComBat.<ELocationID EIdType="pii" ValidYN="Y">100114</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ynirp.2022.100114</ELocationID><Abstract><AbstractText>A... | Advanced brain imaging of neonatal macrostructure and microstructure, which has prognosticating importance, is more frequently being incorporated into multi-center trials of neonatal neuroprotection. Multicenter neuroimaging studies, designed to overcome small sample sized clinical cohorts, are essential but lead to in... |
2,329,430 | Student Team Achievement Division as a tool for peer assisted co-operative learning in neuroanatomy. | Student Team Achievement Division (STAD) is a co-operative learning approach premised on a group learning activity that emphazises learning as a social exchange of knowledge between students, in which each student is accountable for his or her own learning and is also encouraged to assist others in achieving their goal... |
2,329,431 | Chronic lipopolysaccharide impairs motivation when delivered to the ventricles, but not when delivered peripherally in male rats. | Increased neuroinflammation relative to controls is observed in major depression. Moreover, depressive disorders are significantly elevated in conditions which increase neuroinflammation (e.g., brain injury, Parkinson's disease, Alzheimer's disease). To better understand the relationship between neuroinflammation and d... |
2,329,432 | Endoscope-assisted far lateral craniotomy for resection of posterior fossa neurocysticercosis: illustrative case. | Neurocysticercosis is a parasitic infection that commonly affects the ventricles, subarachnoid spaces, and spinal cord of the central nervous system. The authors report an unusual manifestation of purely posterior fossa neurocysticercosis treated with endoscope-assisted open craniotomy for resection.</AbstractText>A 67... |
2,329,433 | Primary intracranial extraosseous Ewing's sarcoma of the skull base in an elderly adult: illustrative case. | Primary extraosseous intracranial Ewing's sarcoma, also known as a peripheral primitive neuroectodermal tumor or "small round blue cell tumor," is an extremely rare entity with limited representation in the literature beyond the pediatric population.</AbstractText>A 67-year-old male suffering occipital headache, nausea... |
2,329,434 | Multiple drug transporters contribute to the brain transfer of levofloxacin.<Pagination><StartPage>445</StartPage><EndPage>457</EndPage><MedlinePgn>445-457</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/cns.13989</ELocationID><Abstract><AbstractText Label="AIMS">The aim of this study was to ass... | The heart is a muscular organ situated in the center of the chest behind the sternum. It consists of four chambers: the two upper chambers are called the right and left atria, and the two lower chambers are called the right and left ventricles. The right atrium and ventricle together are often called the right heart, a... |
2,329,435 | Single-Nucleotide Polymorphisms in Exonic and Promoter Regions of Transcription Factors of Second Heart Field Associated with Sporadic Congenital Cardiac Anomalies. | Multiple second heart field (SHF) transcription factors are involved in cardiac development. In this article we evaluate the relationship between SHF transcription factor polymorphisms and congenital heart disease (CHD). Ten polymorphisms were used for genotyping, and three of these were used for the luciferase assay. ... |
2,329,436 | Extended endoscopic endonasal approach for resecting anterior intrinsic third ventricular craniopharyngioma. | The surgical treatment of the extended endoscopic endonasal approach (EEEA) is a safe and effective treatment for suprasellar craniopharyngiomas. However, due to damage to the hypothalamus and third ventricle floor (TVF), EEEA is generally regarded as unsuitable in treating intrinsic third ventricle craniopharyngioma (... |
2,329,437 | Role of endoscopic endonasal approach for craniopharyngiomas extending into the third ventricle in adults. | •EAA is an innovative, promising, safe and effective approach for 3VCPs.•Key of success is surgeon learning curve in endoscopy and patients selection.•With correct indications, EEA gives GTR and morbidity rate similar to other routes.•Clinical, tumoral and anatomical features should be consi... |
2,329,438 | Chronic Subdural Hematoma (cSDH): A review of the current state of the art. | Incidence of Chronic Subdural Hematoma (cSDH) is rising worldwide, partly due to an aging population, but also due to increased use of antithrombotic medication. Many recent studies have emerged to address current cSDH management strategies.</AbstractText>What is the state of the art of cSDH management.</AbstractText>R... |
2,329,439 | Extracellular signal-regulated kinase-dependent phosphorylation of histone H3 serine 10 is involved in the pathogenesis of traumatic brain injury.<Pagination><StartPage>828567</StartPage><MedlinePgn>828567</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">828567</ELocationID><ELocationID EIdType="doi" Val... | Traumatic brain injury (TBI) induces a series of epigenetic changes in brain tissue, among which histone modifications are associated with the deterioration of TBI. In this study, we explored the role of histone H3 modifications in a weight-drop model of TBI in rats. Screening for various histone modifications, immunob... |
2,329,440 | Cardiac function in critically ill patients with severe COVID: A prospective cross-sectional study in mechanically ventilated patients.<Pagination><StartPage>154166</StartPage><MedlinePgn>154166</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jcrc.2022.154166</ELocationID><ELocationID EIdType=... | The upper airway consists of the nasal cavities, oral cavity, pharynx, and larynx. The pharynx is further subdivided into the nasopharynx, oropharynx, and hypopharynx. The larynx is divided into three regions, dependent on their relationship to the vocal cords (glottis). These areas are the supraglottis, glottis, and s... |
2,329,441 | Peripheral VA-ECMO left ventricular dysfunction: A combined biventricular assistance two case-report.<Pagination><StartPage>583</StartPage><EndPage>586</EndPage><MedlinePgn>583-586</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.redare.2021.04.007</ELocationID><ELocationID EIdType="pii" ValidY... | We report 2 patients with cardiogenic shock that developed severe left ventricular dysfunction due to a non-opening aortic valve while on peripheral VA-ECMO (Veno-Arterial Extracorporeal Membrane Oxygenator). Patients were managed combining a LV (Left Ventricle) mechanical assist device, and central VA - ECMO to suppor... |
2,329,442 | Curative effect of zinc-selenium tea on rat's cardiotoxicity induced by long-term exposure to nonylphenol. | This study aimed to explore whether zinc-selenium tea has an curative effect on the cardiotoxicity induced by nonylphenol (NP), and to compare the effect of zinc-selenium tea and green tea. After drinking of zinc-selenium tea or green tea, compared with the control group, the left ventricular anterior wall became thinn... |
2,329,443 | Road to a rare diagnosis: Description of novel unbalanced translocation causing partial trisomy 17p. | Trisomy 17 is a rare chromosomal disorder. Existing literature on the topic is limited and mostly refer to mosaic Trisomy 17 cases. Our report summarizes the 70-day clinical course of a late preterm neonate with partial Trisomy 17p karyotype 46,XY,der(14)t(14;17)(p11.1;p11.2) dpat. Trisomy 17 due to unbalanced transloc... |
2,329,444 | Full cervical cord tractography: A new method for clinical use. | Despite recent improvements in diffusion-weighted imaging, spinal cord tractography is not used in routine clinical practice because of difficulties in reconstructing tractograms, with a pertinent tri-dimensional-rendering, in a long post-processing time. We propose a new full tractography approach to the cervical spin... |
2,329,445 | Striatal Neurons Partially Expressing a Dopaminergic Phenotype: Functional Significance and Regulation. | Since the discovery of striatal neurons expressing dopamine-synthesizing enzymes, researchers have attempted to identify their phenotype and functional significance. In this study, it was shown that in transgenic mice expressing green fluorescent protein (GFP) under the tyrosine hydroxylase (TH) gene promoter, (i) ther... |
2,329,446 | Novel Insight into the Role of the Kiss1/GPR54 System in Energy Metabolism in Major Metabolic Organs. | The Kiss1/GPR54 system is a multifunctional genetic system with an essential role in regulating energy balance and metabolic homeostasis. In the mammalian hypothalamus, two major populations of neurons, the rostral periventricular region of the third ventricle (RP3V) and the arcuate nucleus (ARC), produced kisspeptin. ... |
2,329,447 | Current Understanding of the Neural Stem Cell Niches. | Neural stem cells (NSCs) are self-renewing, multipotent cells which give rise to all components of the central nervous system (CNS) during embryogenesis, but also activate in response to injury and disease and maintain a certain level of neurogenic activity throughout adulthood. This activity takes place in specialized... |
2,329,448 | A Predictive Nomogram for Postoperative Hydrocephalus After Intra- and Paraventricular Tumor Resection: A Retrospective Study of 196 Patients. | Hydrocephalus is a common complication of intra- and paraventricular tumors both before and after tumor resection. We investigated the risk factors for postoperative hydrocephalus and established a predictive nomogram to improve surgical planning and adjust the frequency of postoperative clinical and radiographic monit... |
2,329,449 | Treatment of arrhythmia disorders in the adult with congenital heart disease: A lesion-specific review.<Pagination><StartPage>1072</StartPage><EndPage>1083</EndPage><MedlinePgn>1072-1083</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.33963/KP.a2022.0235</ELocationID><Abstract><AbstractText>There are... | There are now more adults living with a history of congenital heart disease than there are children. Modern electrophysiologists must familiarize themselves with the most common congenital lesions requiring electrophysiologic care as adults. Advancements in this field have been made most notably with high-resolution 3D... |
2,329,450 | Chronic high-fat diet induces overeating and impairs synaptic transmission in feeding-related brain regions. | Obesity is linked to overeating, which can exacerbate unhealthy weight gain. However, the mechanisms for mediating such linkages are elusive. In the current study, we hypothesized that synaptic remodeling occurs in feeding-related brain regions of obese mice. To investigate this, we established a high-fat diet (HFD)-in... |
2,329,451 | Anesthetic management of a patient with trisomy 18 undergoing esophageal banding and preceding gastrostomy-A case report. | A patient diagnosed with trisomy 18 is at great risk of perioperative morbidity and mortality, especially with complex congenital cardiac anomalies. Here, we report successful anesthetic management of palliative esophageal-banding and gastrostomy for trachea-esophageal fistula in a patient who had a complex congenital ... |
2,329,452 | An International Aircraft Transport of a Neonate From Georgia to Japan. | International air transport over long distances necessitates considerable effort. It is even more challenging when the patient is a neonate and has a congenital disease. We hereby report a case of an international aircraft transport of a neonate from Tbilisi, Georgia to Osaka, Japan. The patient was transported to Osak... |
2,329,453 | Unusual presentation of a common neurosurgical shunt procedure in an adult patient.<Pagination><StartPage>2050313X221129770</StartPage><MedlinePgn>2050313X221129770</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">2050313X221129770</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1177/2050313X22112... | Ventriculoperitoneal shunt surgery is one of the treatments of hydrocephalus. It involves placing a shunt from the cerebral ventricles to the peritoneum serving as a drainage point. Infection and catheter blockage are some of the possible complications resulting from this procedure. In some cases, other incidents such ... |
2,329,454 | [Pulmonary Vascular Remodeling Characteristics of Pulmonary Arterial Hypertension Mouse Model Induced by Left Pneumonectomy and Jugular Vein Injection of Monocrotaline Pyrrole].<Pagination><StartPage>821</StartPage><EndPage>827</EndPage><MedlinePgn>821-827</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y"... | Impella is a device effective for the treatment of cardiogenic shock. However, among small children, its application has limitations due to left ventricle size and vasculature and the turning diameter of the aortic arch. Herein, we report an 11-year-old girl with fulminant myocarditis who was successfully managed with ... |
2,329,455 | Vox2Surf: Implicit Surface Reconstruction from Volumetric Data. | Surface reconstruction from volumetric T1-weighted and T2-weighted images is a time-consuming multi-step process that often involves careful parameter fine-tuning, hindering a more wide-spread utilization of surface-based analysis particularly in large-scale studies. In this work, we propose a fast surface reconstructi... |
2,329,456 | A fetus with Bosch-Boonstra-Schaaf optic atrophy syndrome characterized by bilateral ventricle widening: A case report and related literature review.<Pagination><StartPage>e30558</StartPage><MedlinePgn>e30558</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">e30558</ELocationID><ELocationID EIdType="doi" ... | Coronary arteriovenous fistula (CAVF) is a rare form of congenital heart disease. However, it is the most common type of congenital coronary artery anomalies..An arteriovenous fistula is an abnormal conduit between the artery and vein, typically bypassing the capillaries in between. When present between the c... |
2,329,457 | Expanded endoscopic endonasal approach for the resection of midline craniopharyngiomas with hypothalamic involvement. | With relevant surrounding neurological structures and potential involvement of the hypothalamus, the surgical management of craniopharyngiomas is complex. Compared to the transcranial approach, the expanded endoscopic endonasal approach provides direct access to the supradiaphragmatic and retrochiasmatic areas without ... |
2,329,458 | Morphometric evaluation of great vein of Galen and its clinical implications. | The Galenic venous system plays a vital role in the drainage of blood from deeper parts of the brain. This venous system is contributed by many major veins. These veins are located closer to the pineal gland making the surgical approach in this region difficult. Any accidental injury or occlusion of the vein of Galen c... |
2,329,459 | Single Versus Double Hadad-Bassagasteguy Flap in Expanded Endoscopic Skull-Base Surgery. | The reconstruction of dural defects, after endoscopic removal of skull-base lesions, remains challenging when a large defect or a high flow intraoperative cerebrospinal fluid (CSF) leak is observed. The aim of this study is to describe our preliminary experience with a double Hadad-Bassagasteguy (H-B) flap technique fo... |
2,329,460 | Intracranial tumors mimicking benign paroxysmal positional vertigo: A case series. | A few intracranial lesions may present only with positional vertigo which are very easy to misdiagnose as benign paroxysmal positional vertigo (BPPV); the clinicians should pay more attention to this disease.</AbstractText>To analyze the clinical characteristics of 6 patients with intracranial tumors who only presented... |
2,329,461 | Case Report: A novel desmoplakin mutation in a taiwanese woman with familial dilated cardiomyopathy that necessitated heart transplantation. | Around one-third of patients diagnosed with idiopathic dilated cardiomyopathy (DCM) turn out to be familial cases, in only a few of which the identification of a pathogenic/likely pathogenic variant could be achieved. Cardiomyopathy caused by desmoplakin gene mutations represents a distinct form with a high prevalence ... |
2,329,462 | PPMS: A framework to Profile Primary MicroRNAs from Single-cell RNA-sequencing datasets.<ELocationID EIdType="pii" ValidYN="Y">bbac419</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1093/bib/bbac419</ELocationID><Abstract><AbstractText Label="MOTIVATION">Single-cell/nuclei RNA-sequencing (scRNA-seq) technologie... | Landmarks defining the regions of the hypothalamus include the lamina terminalis, pituitary gland, mammillary bodies, and superior hypothalamic sulcus. The hypothalamus is a bilateral collection of nuclei divided into three zones surrounding the third ventricle and the mammillary bodies. Generally, the periventricular ... |
2,329,463 | Pineal Gland Tumour With Drop Metastases: A Case Report. | Pineal gland tumours are reported rarely in Malayasia and early diagnosis and intervention promise a better prognosis for patients. We report a rare case of pineal gland tumour with drop metastases in the fourth ventricle in a 20-year-old young male with Parinaud syndrome. The patient, who had no underlying medica... |
2,329,464 | Multi-task longitudinal forecasting with missing values on Alzheimer's disease.<Pagination><StartPage>107056</StartPage><MedlinePgn>107056</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.cmpb.2022.107056</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0169-2607(22)00438-2</ELocationID><Ab... | Biventricular metastatic heart tumors from gynecological malignancies presented as an acute coronary syndrome with ST segment elevation are an unusual finding. We present a case of stage-4 vulvar carcinoma that metastasized in both the left and right ventricle. The particularity of the case is the echocardiographic asp... |
2,329,465 | Analysis of the risk factors of post-operative seizure in pediatric patients with hydrocephalus undergoing endoscopic third ventriculostomy. | The cause and mechanism of epilepsy after endoscopic third ventriculostomy (ETV) have still remained elusive. This single-center study aimed to explore and analyze the risk factors of post-operative seizure in pediatric patients with hydrocephalus undergoing ETV.</AbstractText>Data of pediatric patients with hydrocepha... |
2,329,466 | A medical image segmentation method based on multi-dimensional statistical features. | Medical image segmentation has important auxiliary significance for clinical diagnosis and treatment. Most of existing medical image segmentation solutions adopt convolutional neural networks (CNNs). Althought these existing solutions can achieve good image segmentation performance, CNNs focus on local information and ... |
2,329,467 | Diffusion-weighted imaging hyperintensities during the chronic stage of intracerebral hemorrhage with surgery: A new clinical situation or post-surgery artifact? | Diffusion-weighted imaging (DWI) hyperintensities were occasionally seen at previous hematoma in patients several months after intracerebral hemorrhage with surgery. Whether they are newly occurred clinical situations or post-surgery changes is unknown. This study aims to investigate the prevalence and possible mechani... |
2,329,468 | Relationship between adult subventricular neurogenesis and Alzheimer's disease: Pathologic roles and therapeutic implications. | Alzheimer's disease (AD) is a neurodegenerative disease that is characterized by irreversible cognitive declines. Senile plaques formed by amyloid-β (Aβ) peptides and neurofibrillary tangles, consisting of hyperphosphorylated tau protein accumulation, are prominent neuropathological features of AD. Impairme... |
2,329,469 | A large left ventricle and extremely low ejection fraction in a 5-month-old girl with ALCAPA.<Pagination><StartPage>71</StartPage><EndPage>72</EndPage><MedlinePgn>71-72</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.hjc.2022.09.007</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S1109-966... | This study aimed to examine the distribution and quantitative parameters of the epicardiac ventricular neural ganglionated plexus in the hearts of humans and sheep, highlighting the differences of this plexus in humans and large models. Five non-sectioned pressure distended whole hearts of the human newborns and 10 hea... |
2,329,470 | Predictors of survival for pediatric extracorporeal cardiopulmonary resuscitation: A systematic review and meta-analysis.<Pagination><StartPage>e30860</StartPage><MedlinePgn>e30860</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">e30860</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1097/MD.00000... | Pre-excitation is a term that refers to the premature activation of the ventricles. Previously used when referring to Wolff-Parkinson-White (WPW), pre-excitation has been expanded to include any rhythm with antegrade ventricular or retrograde atrial activation via an accessory pathway. These pathways may be partially o... |
2,329,471 | Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection.<Pagination><StartPage>5752</StartPage><MedlinePgn>5752</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">5752</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1038... | Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasite Trypanosoma brucei and induces profound reactivity of glial cells and neuroinflammation when the parasites colonise the central nervous system. However, the transcriptional and functional responses of the brain to chronic T. brucei... |
2,329,472 | Increment of CSF fractalkine-positive microvesicles preceded the spatial memory impairment in amyloid beta neurotoxicity. | Fractalkine (CX3</sub>CL1</sub>) is a key chemokine, affects neuronal cell communication and involves in Alzheimer's disease pathogenesis. Microvesicles (MVs) participate in neuronal cells' cross-talk in physiological and pathological states. Microvesicles released in cerebrospinal fluid (CSF) may provide a valuable fo... |
2,329,473 | A novel modular modeling approach for understanding different electromechanics between left and right heart in rat. | While ion channels and transporters involved in excitation-contraction coupling have been linked and constructed as comprehensive computational models, validation of whether each individual component of a model can be reused has not been previously attempted. Here we address this issue while using a novel modular model... |
2,329,474 | TCB-2, a 5-hydroxytryptamine 2A receptor agonist, disrupts prepulse inhibition in the ventral pallidum and nucleus accumbens. | The 5-hydroxytryptamine 2A (5-HT<sub>2A</sub>) receptor plays an important role in schizophrenia. The 5-HT<sub>2A</sub> receptor is also involved in the regulation of prepulse inhibition (PPI) in rodents. The aim of this study was to determine whether selective 5-HT<sub>2A</sub> receptor agonizts or antagonists may alt... |
2,329,475 | The choroid plexus: a missing link in our understanding of brain development and function.<Pagination><StartPage>919</StartPage><EndPage>956</EndPage><MedlinePgn>919-956</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1152/physrev.00060.2021</ELocationID><Abstract><AbstractText>Studies of the choroid... | Studies of the choroid plexus lag behind those of the more widely known blood-brain barrier, despite a much longer history. This review has two overall aims. The first is to outline long-standing areas of research where there are unanswered questions, such as control of cerebrospinal fluid (CSF) secretion and blood flo... |
2,329,476 | CSF circulation and dispersion yield rapid clearance from intracranial compartments. | In this paper, we used a computational model to estimate the clearance of a tracer driven by the circulation of cerebrospinal fluid (CSF) produced in the choroid plexus (CP) located within the lateral ventricles. CSF was assumed to exit the subarachnoid space (SAS) via different outflow routes such as the parasagittal ... |
2,329,477 | Plastic bronchitis: A rare complication following a motor vehicle collision. | Plastic bronchitis, more appropriately termed chyloptysis, is a rare and potentially fatal condition caused by chylous coating of the airways. These cast coating can dislodge and become an obstructive mass in the patient's airway, necessitating rapid intervention. PB is well described to occur following single ventricl... |
2,329,478 | Proximal ventricular shunt catheter occlusion model. | Proximal ventricular shunt catheter occlusion remains a problematic cause of shunt malfunction, and there is no consistent in vivo or in vitro model to help clinicians and researchers study this phenomenon.</AbstractText>An in vitro model utilizing standard proximal ventricular catheter and biological occluding agents ... |
2,329,479 | Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of postacute sequelae of SARS-CoV-2 infection (PASC) in children and adolescents.<Pagination><StartPage>1241</StartPage><EndPage>1269</EndPage><MedlinePgn>1241-1269</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="... | Pulmonary atresia with intact ventricular septum is a complex cyanotic congenital heart lesion with the potential for myocardial ischaemia due to the presence of coronary artery anomalies. We present a case of a two-day-old baby with postnatal diagnosis of pulmonary atresia with intact ventricular septum in whom non-in... |
2,329,480 | Massive cardiopulmonary cement embolism with cardiac perforation after vertebroplasty: a case series. | The prevalence of cement embolism after percutaneous vertebroplasty ranges from 2.1 to 26%, in literature. Even if most cases remain asymptomatic, intracardiac cement embolism becomes symptomatic in up to 8.3% of the cases.</AbstractText>We report a case series of two cases with massive cardiopulmonary cement embolism,... |
2,329,481 | Surgical Treatment of Pineal Region Tumors: An 18 year-Experience at a Single Institution. | The pineal tumor was once considered as a restricted area for surgery. Such cases are rare, with many different opinions on surgical treatment. This study aimed to review our experience of tumor treatment in the pineal region and explore the optimal treatment strategy.</AbstractText>The clinical data of 72 patients wit... |
2,329,482 | The effects of citalopram, SB-334867 and orexin-1, alone or in various combinations, on the anxiogenic-like effects of REM sleep deprivation in male mice. | Sleep deprivation may induce anxiety. On the other hand, anxiety disorders elicit main changes in the quality of sleep. Moreover, orexin and citalopram play a role in the modulation of insomnia and mood diseases. Thus, we planned preclinical research to evaluate the effect of combinations of orexin agents and citalopra... |
2,329,483 | Incidental accumulation of Technetium-99m pertechnetate in subacute cerebral infarction: A case report. | When interpreting nuclear medicine images, unexpected findings are sometimes encountered. Recognizing these findings and determining the mechanism of their occurrence could have a significant impact on early diagnosis of critical diseases and the appropriate management of patients.</AbstractText>A 59-year-old man was a... |
2,329,484 | The neural stem cell properties of Pkd2l1<sup>+</sup> cerebrospinal fluid-contacting neurons <i>in vivo</i>. | The neural stem cells (NSCs) in the ventricular-subventricular zone of the adult mammalian spinal cord may be of great benefit for repairing spinal cord injuries. However, the sources of NSCs remain unclear. Previously, we have confirmed that cerebrospinal fluid-contacting neurons (CSF-cNs) have NSC potential <i>in vit... |
2,329,485 | Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit. | Postoperative delirium is common in patients who undergo neurosurgery for craniocerebral injury. However, there is no specific medical test to predict postoperative delirium to date.</AbstractText>To explore risk factors for postoperative delirium in patients with craniocerebral injury in the neurosurgery intensive car... |
2,329,486 | High-Grade Supratentorial Intraventricular Tumours in Adults. | High-grade Intraventricular tumours are rarely encountered. Many of these tumours will have similar patterns on imaging of signal intensity and contrast enhancement. As IVT are regularly not targetable by radiation or systemic therapy, until now, surgical resection presents the treatment of choice. |
2,329,487 | An Alzheimer's Disease Mechanism Based on Early Pathology, Anatomy, Vascular-Induced Flow, and Migration of Maximum Flow Stress Energy Location with Increasing Vascular Disease. | This paper suggests a chemical mechanism for the earliest stages of Alzheimer's disease (AD). Cerebrospinal fluid (CSF) flow stresses provide the energy needed to induce molecular conformation changes leading to AD by initiating amyloid-β (Aβ) and tau aggregation. Shear and extensional flow stresses initiat... |
2,329,488 | NO<sub>2</sub> exposure contributes to cardiac hypertrophy in male mice through apoptosis signaling pathways.<Pagination><StartPage>136576</StartPage><MedlinePgn>136576</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.chemosphere.2022.136576</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S... | Nitrogen dioxide (NO<sub>2</sub>) is one of the most common indoor and outdoor air pollutants. Inhalation of NO<sub>2</sub> is associated with an increased risk of health problems, especially cardiovascular diseases. However, the underlying pathogenic mechanisms still remain unclear. In this study, we exposed C57BL/6J ... |
2,329,489 | Heterogeneity in the size of the apical surface of cortical progenitors.<Pagination><StartPage>363</StartPage><EndPage>376</EndPage><MedlinePgn>363-376</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/dvdy.539</ELocationID><Abstract><AbstractText Label="BACKGROUND">The apical surface (AS) of epit... | Prone position has shown beneficial hemodynamic effects in patients with right ventricular dysfunction associated with acute respiratory distress syndrome decreasing the right ventricle afterload. We describe the case of a 57-year-old man with right ventricular dysfunction associated with pulmonary thromboembolism with... |
2,329,490 | Long-term outcomes of elderly patients receiving continuous flow left ventricular support.<Pagination><StartPage>5685</StartPage><MedlinePgn>5685</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/jocs.16973</ELocationID><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Vasavada</LastName><F... | The bidirectional Glenn (BDG) and hemi-Fontan are surgical techniques used to create superior cavopulmonary anastomosis, the second stage repair in Fontan completion. They are performed in patients with an anatomic or functional single ventricle. Whether it is right or left, the single ventricle must therefore provide ... |
2,329,491 | Microendoscopic transventricular deep brain stimulation of the anterior nucleus of the thalamus as a safe treatment in intractable epilepsy: A feasibility study. | Deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) is proposed in patients with severe intractable epilepsy. When used, the transventricular approach increases the risk of bleeding due the anatomy around the entry point in the thalamus. To avoid such a complication, we used a transventricular mi... |
2,329,492 | Assessment of foetal ventriculomegaly from prenatal to early postnatal period: a single-centre retrospective cohort study. | The aim of this study was to evaluate the early neonatal outcomes of cases with foetal ventriculomegaly (VM) and to investigate the aetiological and prognostic factors according to the degree of VM in a single tertiary referring centre. The medical records of 87 foetuses diagnosed with VM (≥10 mm) within ... |
2,329,493 | Impaired Neurovascular Function Underlies Poor Neurocognitive Outcomes and Is Associated with Nitric Oxide Bioavailability in Congenital Heart Disease. | We use a non-invasive MRI proxy of neurovascular function (pnvf) to assess the ability of the vasculature to supply baseline metabolic demand, to compare pediatric and young adult congenital heart disease (CHD) patients to normal referents and relate the proxy to neurocognitive outcomes and nitric oxide bioavailability... |
2,329,494 | Bridging with Veno-Arterial Extracorporeal Membrane Oxygenation in Children: A 10-Year Single-Center Experience. | Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is frequently used in children with and without congenital heart disease (CHD). This study, of a single-center and retrospective design, evaluated the use and timing of V-A ECMO in a pediatric cohort who underwent V-A ECMO implantation between January 2009 an... |
2,329,495 | Liver X Receptor Regulation of Glial Cell Functions in the CNS. | In this review, we discuss the role of liver X receptors (LXRs) in glial cells (microglia, oligodendrocytes and astrocytes) in the central nervous system (CNS). LXRs are oxysterol-activated nuclear receptors that, in adults, regulate genes involved in cholesterol homeostasis, the modulation of inflammatory responses an... |
2,329,496 | Beneficial Effects of Empagliflozin Are Mediated by Reduced Renal Inflammation and Oxidative Stress in Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein. | Gliflozins (inhibitors of sodium-glucose cotransporter 2) show many beneficial actions beyond their antidiabetic effects. The underlying mechanisms of these additional protective effects are still not well understood, especially under non-diabetic conditions. Therefore, we analyzed the effects of empagliflozin in young... |
2,329,497 | Primary Cilia Influence Progenitor Function during Cortical Development. | Corticogenesis is an intricate process controlled temporally and spatially by many intrinsic and extrinsic factors. Alterations during this important process can lead to severe cortical malformations. Apical neuronal progenitors are essential cells able to self-amplify and also generate basal progenitors and/or neurons... |
2,329,498 | Human antimicrobial peptide LL-37 contributes to Alzheimer's disease progression. | As a prime mover in Alzheimer's disease (AD), microglial activation requires membrane translocation, integration, and activation of the metamorphic protein chloride intracellular channel 1 (CLIC1), which is primarily cytoplasmic under physiological conditions. However, the formation and activation mechanisms of functio... |
2,329,499 | Racemose neurocysticercosis simulating tuberculous meningitis. | We report a patient with racemose neurocysticercosis, highlighting the diagnostic and management issues. A 37-year-old male had headaches, fever, and seizures for 8 months. He had a positive tuberculin test, cerebrospinal fluid pleocytosis, and hydrocephalus and exudates on MRI. His symptoms rapidly resolved follo... |
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