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2,329,700 | Endoscopic endonasal approach for infradiaphragmatic craniopharyngiomas: a multicentric Italian study. | Infradiaphragmatic craniopharyngiomas (ICs) represent a distinct subtype, harboring a sellar-suprasellar origin and generally growing in the extra-arachnoidal space contained by the diaphragma sellae. They have been considered ideal for surgical removal through the transsphenoidal approach since the 1960s. The authors ... |
2,329,701 | Extra-axial endoscopic third ventriculostomy: preliminary experience with a technique to circumvent conventional endoscopic third ventriculostomy complications. | Endoscopic third ventriculostomy (ETV) is mostly safe but may have serious complications. Most of the complications are inherent to the procedure's intra-axial nature. This study aimed to explore an alternative route to overcome inherent issues with conventional ETV. The authors performed supraorbital, subfrontal extra... |
2,329,702 | Median trans-atlanto-occipital membrane microsurgical approach to the posterior cranial fossa without craniotomy. | Minimally invasive approaches are becoming increasingly popular and contributing to improving the results of the surgical treatment of a wide variety of intracranial pathologies. Fifteen patients with posterior cranial fossa tumors underwent microsurgery through the atlanto-occipital membrane without resection of any b... |
2,329,703 | Intraventricular metastasis from carcinoma breast masquerading as choroid plexus neoplasm: A case report. | Metastatic tumors in the brain represent the most common type of intracranial neoplasm, comprising 8-10% of all brain tumors. 30% of such tumors are primarily of breast origin in females. Brain parenchymal metastasis is the more common presentation. Intraventricular spread is rare, seen in less than 5% of cases in a me... |
2,329,704 | Use of a telovelar approach for complete resection of a choroid plexus tumor in a dog. | To describe a telovelar approach to the fourth ventricle for excision of a choroid plexus tumor within the ventricle.</AbstractText>A 3-year-old entire male Chihuahua.</AbstractText>Case report METHODS: A 3-year-old dog with two-month history of progressive vestibular signs and subdued mentation was diagnosed with a fo... |
2,329,705 | Estimation of biological heart age using cardiovascular magnetic resonance radiomics. | We developed a novel interpretable biological heart age estimation model using cardiovascular magnetic resonance radiomics measures of ventricular shape and myocardial character. We included 29,996 UK Biobank participants without cardiovascular disease. Images were segmented using an automated analysis pipeline. We ext... |
2,329,706 | Guanidinoacetic acid provides superior cardioprotection to its combined use with betaine and (or) creatine in HIIT-trained rats. | This study aimed to determine how guanidinoacetic acid (GAA) or its combined administration with betaine (B) or creatine (C) influences the cardiac function, morphometric parameters, and redox status of rats subjected to high-intensity interval training (HIIT). This research was conducted on male Wistar albino rats exp... |
2,329,707 | Tubulinopathy Presenting as Developmental and Epileptic Encephalopathy. | Tubulin proteins play a role in the cortical development. Mutations in the tubulin genes affect patients with brain malformations. The present report describes two cases of developmental and epileptic encephalopathy (DEE) due to tubulinopathy. Case 1, a 23-year-old boy, was found to have a brain malformation with moder... |
2,329,708 | Hippocampal semaphorin 3B improves depression-like behaviours in mice by upregulating synaptic plasticity and inhibiting neuronal apoptosis. | Depression is a global health problem, and there is a pressing need for a better understanding of its pathogenesis. Semaphorin 3B (Sema 3B) is an important axon guidance molecule that is primarily expressed in neurons and contributes to synaptic plasticity. Our previous studies using a high-throughput microarray assay ... |
2,329,709 | Spatial distribution and network morphology of epicardial, endocardial, interstitial, and Purkinje cell-associated elastin fibers in porcine left ventricle. | Cardiac extracellular matrices (ECM) play crucial functional roles in cardiac biomechanics. Previous studies have mainly focused on collagen, the major structural ECM in heart wall. The role of elastin in cardiac mechanics, however, is poorly understood. In this study, we investigated the spatial distribution and micro... |
2,329,710 | Effects of Gold Nanoparticles Functionalized with Bioactive Compounds from <i>Cornus mas</i> Fruit on Aorta Ultrastructural and Biochemical Changes in Rats on a Hyperlipid Diet-A Preliminary Study. | Cornus mas L. extract (CM) presents hypolipidemic, antioxidant and anti-inflammatory activity. Gold nanoparticles (AuNPs) are considered potent delivery systems and may be used to release pharmaceutical compounds at the level of injury. In our study, we used gold nanoparticles functionalized with bioactive compounds fr... |
2,329,711 | Effects of Maternal Nutrient Restriction and Melatonin Supplementation on Cardiomyocyte Cell Development Parameters Using Machine Learning Techniques. | The objective of the current study was to examine the effects of maternal feed restriction and melatonin supplementation on fetal cardiomyocyte cell development parameters and predict binucleation and hypertrophy using machine learning techniques using pregnant beef heifers. Brangus heifers (n = 29) were assigned to on... |
2,329,712 | Neurotrophic factor-secreting cells restored endogenous hippocampal neurogenesis through the Wnt/β-catenin signaling pathway in AD model mice. | Impairment in neurogenesis correlates with memory and  cognitive dysfunction in AD patients. In the recent decade, therapies with stem cell bases are growing and proved to be efficient. This study is a preliminary attempt to explore the impact of NTF-SCs on hippocampal neurogenesis mediated by the Wnt/β-cate... |
2,329,713 | Outcomes after gamma knife radiosurgery for intraventricular meningiomas. | Intraventricular meningiomas (IVMs) are rare tumors with considerable treatment-associated morbidity due to their challenging location. Treatment with stereotactic radiosurgery (SRS) is sparsely reported in the literature. We describe our experience over the last 35 years using Gamma knife radiosurgery (GKRS) for ... |
2,329,714 | Towards the interpretability of deep learning models for multi-modal neuroimaging: Finding structural changes of the ageing brain. | Brain-age (BA) estimates based on deep learning are increasingly used as neuroimaging biomarker for brain health; however, the underlying neural features have remained unclear. We combined ensembles of convolutional neural networks with Layer-wise Relevance Propagation (LRP) to detect which brain features contribute to... |
2,329,715 | Choroid plexus tissue perfusion and blood to CSF barrier function in rats measured with continuous arterial spin labeling. | The choroid plexus (ChP) of the cerebral ventricles is a source of cerebrospinal fluid (CSF) production and also plays a key role in immune surveillance at the level of blood-to-CSF-barrier (BCSFB). In this study, we quantify ChP blood perfusion and BCSFB mediated water exchange from arterial blood into ventricular CSF... |
2,329,716 | Thyroid-stimulating hormone and mortality in pulmonary arterial hypertension.<ELocationID EIdType="pii" ValidYN="Y">e001348</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1136/bmjresp-2022-001348</ELocationID><Abstract><AbstractText Label="INTRODUCTION">Pulmonary arterial hypertension (PAH) remains a serious an... | We studied pulmonary artery size, reinterventions, and panel reactive antibodies in patients with single-ventricle physiology who underwent a pulmonary arterioplasty with decellularized (DAPAP) and non-decellularized allogeneic pulmonary artery patches (non-DAPAP). Retrospective review identified 59 patients with singl... |
2,329,717 | Histological Identification and Quantification of Eosinophils and Ascites in Leghorn Chickens Treated with High Oral Concentrations of NaCl-Pilot Study. | The purpose of this pilot study was to determine the role played by eosinophils in NaCl poisoning and right cardiac hypertrophy (ascitic syndrome) in Leghorn chickens, as well as the histological findings in the central nervous system (CNS), liver, and kidney. Moreover, the hypertrophy of the right ventricle index (HRV... |
2,329,718 | Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar development. | Formation of the mouse cerebellum is initiated in the embryo and continues for a few weeks after birth. Double-mutant mice lacking platelet-derived growth factor C (PDGF-C) and that are heterozygous for platelet-derived growth factor receptor alpha (Pdgfc-/-; PdgfraGFP/+) develop cerebellar hypoplasia and malformation ... |
2,329,719 | Costs and Its Determinants in Pituitary Tumour Surgery. | Value-based healthcare (VBHC) provides a framework to improve care by improving patient outcomes and reducing healthcare costs. To support value-based decision making in clinical practice we evaluated healthcare costs and cost drivers in perioperative care for pituitary tumour patients.</AbstractText>We retrospectively... |
2,329,720 | Bone Specific Alkaline Phosphatase and Serum Calcification Propensity Are Not Influenced by Etelcalcetide vs. Alfacalcidol Treatment, and Only Bone Specific Alkaline Phosphatase Is Correlated With Fibroblast Growth Factor 23: Sub-Analysis Results of the ETACAR-HD Study. | Secondary hyperparathyroidism in chronic kidney disease poses a major risk factor for vascular calcification and high bone turnover, leading to mineralization defects. The aim was to analyze the effect of active vitamin D and calcimimetic treatment on fibroblast growth factor 23 (FGF23), serum calcification propensity ... |
2,329,721 | [Development and Evaluation of Prognostic Nomogram Model for Adult Ventricle Glioma Patients].<Pagination><StartPage>588</StartPage><EndPage>596</EndPage><MedlinePgn>588-596</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.12182/20220760203</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCat... | The term atrioventricular (AV) dissociation describes a family of arrhythmias where independent pacemakers control the atria and ventricles. The standard activation of the cardiac circuits works in the order of impulse transmission from the sinoatrial (SA) node to the atria, the AV node, and ventricular activation... |
2,329,722 | T1 values and extracellular volume fraction in asymptomatic subjects: variations in left ventricular segments and correlation with cardiovascular risk factors. | To evaluate variations in pre-contrast (preT1) and post-contrast (postT1) myocardial T1 values and extracellular volume fraction (ECV) according to left ventricular (LV) segments and to find correlations between them and cardiovascular risk factors. The 233 asymptomatic subjects (210 men, 23 women; aged 54.1 &#x... |
2,329,723 | Diagnosis and Surgical Management of Neonatal Hydrocephalus. | Neonatal hydrocephalus represents an important pathological condition with significant impact on medical care and neurocognitive development. This condition requires early recognition, appropriate medical and surgical management, and long-term surveillance by clinicians and pediatric neurosurgeons. Common etiologies of... |
2,329,724 | Proteomic and Metabolomic Analyses of Right Ventricular Failure due to Pulmonary Arterial Hypertension.<Pagination><StartPage>834179</StartPage><MedlinePgn>834179</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">834179</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3389/fmolb.2022.834179</ELocati... | Right ventricular failure (RVF) is the independent and strongest predictor of mortality in pulmonary arterial hypertension (PAH), but, at present, there are no preventive and therapeutic strategies directly targeting the failing right ventricle (RV). The underlying mechanism of RV hypertrophy (RVH) and dysfunction need... |
2,329,725 | Ventriculocholecystal Shunt as a Salvage Procedure in Shunt Dependent Hydrocephalic Children with Compromised Peritoneal Cavity. | Multiple shunt revisions are a formidable challenge in neurosurgery, as the surgeon faces progressive difficulties in finding suitable distal sites for implantation. Gallbladder offers an alternative safe implantation site of distal catheter in case of repeated peritoneal failures. We describe two such cases done in ou... |
2,329,726 | Cerebrospinal Fluid Flow Analysis in Tuberculous Meningitis Using Phase Contrast Technique on 3 Tesla MRI: A New Paradigm and Our Initial Experience. | Phase-contrast magnetic resonance imaging (PC-MRI) has been used for studying cerebrospinal fluid (CSF) dynamics in various CSF related disorders at aqueduct of Sylvius.</AbstractText>To analyze the CSF flow dynamics qualitatively and quantitatively using PC-MRI across the aqueduct of Sylvius in diagnosed patients of t... |
2,329,727 | Risk Factors for and Outcomes of Postoperative Entrapped Temporal Horn in Trigone Meningiomas. | Meningioma in the ventricle triangle area is a benign tumor that can be cured by surgery, but postoperative entrapped temporal horn may seriously affect the patient's quality of life and even require a second operation. Currently, there are few reports on this complication.</AbstractText>The risk factors and prognosis ... |
2,329,728 | Surgical Treatment of IV Ventricle Calcifying Pseudoneoplasm of the Neuraxis (CAPNON) Operative Nuances. | Calcifying pseudoneoplasm of the neuroaxis (CAPNON) is a rare, slow growing, and generally benign fibro osseous mass that can emerge throughout the entire central nervous system (CNS). When diagnosed, prompt surgical treatment can determine a good neurological outcome and possibly curative resolution. The objective of ... |
2,329,729 | Unveiling the gut-brain axis: structural and functional analogies between the gut and the choroid plexus vascular and immune barriers. | The vasculature plays an essential role in the development and maintenance of blood-tissue interface homeostasis. Knowledge on the morphological and functional nature of the blood vessels in every single tissue is, however, very poor, but it is becoming clear that each organ is characterized by the presence of endothel... |
2,329,730 | Dimorphic evaluation of hippocampal changes in rat model of demyelination: A comparative functional, morphometric, and histological study. | Multiple sclerosis (MS) is the most common autoimmune disease. Progressive depletion of the brain and spinal cord tissue appears at the onset of the disease. Several studies have shown the increased size of the ventricles of the brain and decreases in the area of the corpus callosum and the width of the brain. Other im... |
2,329,731 | A novel stem cell type at the basal side of the subventricular zone maintains adult neurogenesis. | According to the current consensus, murine neural stem cells (NSCs) apically contacting the lateral ventricle generate differentiated progenitors by rare asymmetric divisions or by relocating to the basal side of the ventricular-subventricular zone (V-SVZ). Both processes will ultimately lead to the generation of adult... |
2,329,732 | Mechanisms of central brain atrophy in multiple sclerosis. | Change in ventricular volume has been suggested as surrogate measure of central brain atrophy (CBA) applicable to the everyday management of multiple sclerosis (MS) patients.</AbstractText>We investigated the contribution of inflammatory activity (including the severity of lesional tissue damage) to CBA.</AbstractText>... |
2,329,733 | Conservation of miR combo based direct cardiac reprogramming. | There is considerable interest in regenerating the injured heart by reprogramming resident fibroblasts into new functional cardiomyocytes. Cardiac reprogramming has been achieved via transcription factors or miRNAs. Transcription factor combinations appear to be species-specific as evidenced by the fact that combinatio... |
2,329,734 | A case of McKusick-Kaufman syndrome with perinatal diagnosis: Case report and literature review. | and importance: McKusick-Kaufman syndrome (MKS) is a rarely reported autosomal recessive syndrome characterized by hydrometrocolpos (HMC), polydactyly and various gastrointestinal and renal manifestations.</AbstractText>We present a case of suspected MKS in a prenatal ultrasound with dilated lateral ventricles of the b... |
2,329,735 | Decreased Brain Ventricular Volume in Psychiatric Inpatients with Serotonin Reuptake Inhibitor Treatment. | Brain ventricles have been reported to be enlarged in several neuropsychiatric disorders and in aging. Whether human cerebral ventricular volume can decrease over time with psychiatric treatment is not well-studied. The aim of this study was to examine whether inpatients taking serotonin reuptake inhibitors (SRI) exhib... |
2,329,736 | Effect of taurine administration on symptoms, severity, or clinical outcome of dilated cardiomyopathy and heart failure in humans: a systematic review.<Pagination><StartPage>9</StartPage><MedlinePgn>9</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">9</ELocationID><ELocationID EIdType="doi" ValidYN="Y">1... | <b>Background:</b> Taurine, 2-aminoethanesulfonic acid, is an amino acid found in animal products. Taurine is produced for human consumption as a supplement and ingredient in beverages. Supplementation is a safe, inexpensive, and effective treatment for dilated cardiomyopathy (DCM) in domestic mammals, however it is cu... |
2,329,737 | Quantitative Neuroanatomical Phenotyping of the Embryonic Mouse Brain. | Congenital neurodevelopmental anomalies are present from birth and are characterized by an abnormal development of one or more structures of the brain. Brain structural anomalies are highly comorbid with neurodevelopmental and neuropsychiatric disorders such as intellectual disability, autism spectrum disorders, epilep... |
2,329,738 | Stereotactic surgery for neurocysticercosis of the 4th ventricle: illustrative cases. | Neurocysticercosis, caused by the larval stage of Taenia solium</i>, affects the cerebral ventricles in 20-30% of cases and may lead to hydrocephalus and other neurological morbidity. Conventional treatment for cysts in the 4th ventricle includes open surgery (suboccipital approach) and neuroendoscopy, with the latter ... |
2,329,739 | Posttraumatic Parinaud's syndrome as a contrecoup injury in a case of closed head trauma. | The purpose of the study was to present a rare case of post-traumatic Parinaud's syndrome with a history of closed head injury. The clinical characteristics, examination, and management are presented in a 12-year-old boy who was a victim of physical violence at the hands of a young boy who punched him in his chin with ... |
2,329,740 | COVID-19 Resulting in Global Stress Cardiomyopathy in a Young Female. | Takotsubo cardiomyopathy, also called stress cardiomyopathy, is a form of reversible cardiomyopathy that occurs during periods of emotional or physical stress. There are many variants of takotsubo. They are classified depending on the region of hypokinesis: the most common four variants include the apical/typical ... |
2,329,741 | Diagnostic Value of Abdominal B-Ultrasound for Congenital Heart Disease Complicated with Extracardiac Malformation in the Second Trimester of Pregnancy. | To explore the diagnostic value of abdominal B-ultrasound in the diagnosis of congenital heart disease complicated with extracardiac malformations in the second trimester of pregnancy.</AbstractText>50 pregnant women with congenital cardiac malformations and extracardiac malformations diagnosed in our hospital from 201... |
2,329,742 | Ventricular volume in relation to lumbar CSF levels of amyloid-β 1-42, tau and phosphorylated tau in iNPH, is there a dilution effect? | Levels of the biomarkers amyloid-β 1-42 (Aβ42), tau and phosphorylated tau (p-tau) are decreased in the cerebrospinal fluid (CSF) of patients with idiopathic normal pressure hydrocephalus (iNPH). The mechanism behind this is unknown, but one potential explanation is dilution by excessive CSF volumes. The ai... |
2,329,743 | Anatomy of the Ventricles, Subarachnoid Spaces, and Meninges. | The ventricular system, subarachnoid spaces, and meninges are structures that lend structure, support, and protection to the brain and spinal cord. This article provides a detailed look at the anatomy of the intracranial portions of these structures with a particular focus on neuroimaging methods. |
2,329,744 | Percutaneous jugular leadless pacemaker implantation in a pediatric patient.<Pagination><StartPage>2111</StartPage><EndPage>2115</EndPage><MedlinePgn>2111-2115</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/jce.15620</ELocationID><Abstract><AbstractText Label="INTRODUCTION">Leadless cardiac pac... | The hippocampus is the "flash drive" of the human brain and is often associated with memory consolidation and decision making, but it is far more complex in structure and function than a flash drive. The hippocampus is a convex elevation of gray matter tissue within the parahippocampal gyrus inside the inferior tempora... |
2,329,745 | Factors Influencing Craniospinal Relapse of Intracranial Germinoma After Complete Remission. | To evaluate the pathomechanism of the recurrence of intracranial germinoma after complete response and to confirm the association of the initial magnetic resonance imaging and therapeutic factors with recurrence.</AbstractText>This study included patients who were followed up for ≥5 years and who were ... |
2,329,746 | Synergistic effects of hIAPP and Aβ<sub>1</sub><sub>-</sub><sub>42</sub> impaired the olfactory function associated with the decline of adult neurogenesis in SVZ. | According to many in the field，the prevalence of Alzheimer's disease (AD) in type II diabetes (T2DM) populations is considerably higher than that in the normal population. Human islet amyloid polypeptide (hIAPP) is considered to be a common risk factor for T2DM and AD. Preliminary observations around T2DM animal... |
2,329,747 | Accurate image-based CSF volume calculation of the lateral ventricles. | The size/volume of the brain's ventricles is essential in diagnosing and treating many neurological disorders, with various forms of hydrocephalus being some of the most common. Initial ventricular size and changes, if any, in response to disease progression or therapeutic intervention are monitored by serial imaging m... |
2,329,748 | Third Ventricle Craniopharyngioma Intraventricular Tumor: A Case Report and a Brief Literature Review. | Craniopharyngioma is a rare embryonic malformation, usually benign, of the sellar or parasellar regions. In this study, an uncommon case of third ventricle craniopharyngioma and a succinct review of its prevalence are presented. Even with low mortality rates, these injuries involve a high degree of endocrinological, vi... |
2,329,749 | Diagnosis of symmetric bilateral lateral ventricular subependymomas: A case report. | Subependymomas are rare benign tumors that are hypovascular and noninvasive. Subependymomas tend to present as solitary lesions in the fourth ventricle or the frontal horn of the lateral ventricle. When multiple lesions are present, determining the correct diagnosis between subependymoma and other intraventricular neop... |
2,329,750 | Schizencephaly as an Unusual Cause of Adult-Onset Epilepsy: A Case Report. | Schizencephaly is a very rare anatomical malformation of the cerebrum characterized by a cleft extending from the cortex to the ventricles. Usually, this disease is diagnosed at a very young age or in early adulthood. Symptoms may vary depending on the site and the size of the malformation. Here, we are describing the ... |
2,329,751 | Fast acquisition of left and right ventricular function parameters applying cardiovascular magnetic resonance in clinical routine - validation of a 2-shot compressed sensing cine sequence.<Pagination><StartPage>266</StartPage><EndPage>275</EndPage><MedlinePgn>266-275</MedlinePgn></Pagination><ELocationID EIdType="doi" ... | Infants born with single ventricle physiology that require an aorto-pulmonary shunt are at high risk for sudden cardiac death, particularly during the interstage period between the first-stage palliation and the second-stage palliation. Home monitoring programs have decreased interstage mortality in the hypoplastic lef... |
2,329,752 | Diffuse Myocardial Fibrosis at Cardiac MRI in Young Adults Born Prematurely: A Cross-sectional Cohort Study. | To measure native T1 values, a marker of diffuse fibrosis, by using cardiac MRI (CMR) in young adults born prematurely.</AbstractText>This secondary analysis of a prospective cohort study included young adults born moderately to extremely preterm and age-matched, term-born participants. CMR was performed with a 3.0-T i... |
2,329,753 | Clinically important changes in right ventricular volume and function in pulmonary arterial hypertension assessed with cardiac magnetic resonance imaging. | Right ventricular (RV) dilatation predicts clinical worsening in pulmonary arterial hypertension (PAH) and RV volumes can be measured with high precision using cardiovascular magnetic resonance imaging. In regular follow-up of patients and in studies of improvement in RV function, knowledge of clinically significa... |
2,329,754 | Symptomatic care of late-onset Alexander disease presenting with area postrema-like syndrome with prednisolone; a case report. | Alexander disease (AxD) is classified into AxD type I (infantile) and AxD type II (juvenile and adult form). We aimed to determine the potential genetic cause(s) contributing to the AxD type II manifestations in a 9-year-old male who presented area postrema-like syndrome and his vomiting and weight loss improved after ... |
2,329,755 | Ventriculomegaly in Cavalier King Charles Spaniels with Chiari-like malformation: relationship with clinical and imaging findings. | The objective of this study was to calculate lateral ventricles dimension in Cavalier King Charles Spaniel dogs with Chiari-like malformation and investigate the association between ventriculomegaly and signalment, clinical signs, ventricular asymmetry, grade of Chiari-like malformation, syringomyelia and index of medu... |
2,329,756 | Leptin receptor-expressing cells in the ventromedial nucleus of the hypothalamus contribute to enhanced CCK-induced satiety following central leptin injection. | Others have shown that leptin and cholecystokinin (CCK) act synergistically to suppress food intake. Experiments described here tested whether leptin in the ventromedial hypothalamus (VMH) contributes to the synergy with peripheral CCK in male Sprague Dawley rats. A subthreshold injection of 50-ng leptin into the VMH 1... |
2,329,757 | Pineal cysts without hydrocephalus: microsurgical resection via an infratentorial-supracerebellar approach-surgical strategies, complications, and their avoidance. | Indications for surgery of pineal cysts without ventriculomegaly are still under debate. In view of the limited data for pineal cyst resection in the absence of hydrocephalus, and the potential risk of this approach, we have analyzed our patient cohort focusing on strategies to avoid complications according to our expe... |
2,329,758 | Efficacy of endoscopic management of primary central nervous system lymphoma: a multicentric study and literature review. | To date, confined intra-ventricular localization of primary central nervous system lymphoma (PCNSL) has been usually managed with open surgical resection and/or stereotactic biopsy; nonetheless, the endoscopic approach to such localization can provide many advantages over standard microsurgery and/or stereotactic biops... |
2,329,759 | Intraventricular CNS aspergillosis in a patient with prior history of COVID-19: Case report and review of literature. | Although some immunocompetent patients have developed invasive aspergillosis, the vast majority of cases are seen in immunocompromised patients. COVID-19 infection has been proposed to cause immune dysfunction or suppression, which predisposes patients to fungal co-infections such as mucormycosis and aspergillosis.</Ab... |
2,329,760 | Detection of Spontaneous Bone Metastases of Solid Human Tumor Xenografts in Mice. | The formation of bone metastases from solid primary tumors comprises several processes following each other in a sequential order in terms of the metastatic cascade. The most widely used preclinical models of bone metastasis formation do not reflect this pathophysiological situation as they are based on intracardiac (l... |
2,329,761 | Glioblastoma disrupts the ependymal wall and extracellular matrix structures of the subventricular zone. | Glioblastoma (GBM) is the most aggressive and common type of primary brain tumor in adults. Tumor location plays a role in patient prognosis, with tumors proximal to the lateral ventricles (LVs) presenting with worse overall survival, increased expression of stem cell genes, and increased incidence of distal tumor recu... |
2,329,762 | Differential spatial distribution of white matter lesions in Parkinson's and Alzheimer's diseases and cognitive sequelae. | White Matter Lesions (WML) are a radiological finding common in aged subjects. We explored the impact of WML on underlying neurodegenerative processes. We focused on the impact of WML on two neurodegenerative diseases with different pathology. In this cross-sectional study of 137 subjects (78 female, 59 men, mean age 6... |
2,329,763 | Cardiac remodeling in amateur triathletes after 24 weeks of exercise training for a half-Ironman event: a brief report.<Pagination><StartPage>367</StartPage><EndPage>372</EndPage><MedlinePgn>367-372</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.23736/S0022-4707.22.14108-3</ELocationID><Abstract><Ab... | This is a case-control study of our experience of mid-term follow-up of 40 children who had a transcatheter closure of very large atrial septal defects group (1). All cases had an atrial septal defect device size more than 1.5 times their weight, a ratio considered a contraindication for trans catheter closure (TCC) in... |
2,329,764 | Bilateral Vocal Cord Paralysis Associated with Meningeal Carcinomatosis from Lung Adenocarcinoma. | Cranial neuropathy is a clinical manifestation of meningeal carcinomatosis (MC); however, the glossopharyngeal and vagus nerves are rarely impaired. Therefore, dysphagia and bilateral vocal cord paralysis (BVCP) are extremely rare manifestations of MC. Here, we present a case of MC from a lung adenocarcinoma presenting... |
2,329,765 | Resuscitation of Term Compromised and Asphyctic Newborns: Better with Intact Umbilical Cord? | The authors hypothesize that particularly severely compromised and asphyctic term infants in need of resuscitation may benefit from delayed umbilical cord clamping (after several minutes). Although evidence is sparse, the underlying pathophysiological mechanisms support this assumption. For this review the authors have... |
2,329,766 | Prediction of high and low disease activity in early MS patients using multiple kernel learning identifies importance of lateral ventricle intensity. | Lack of easy-to-interpret disease activity prediction methods in early MS can lead to worse patient prognosis.</AbstractText>Using machine learning (multiple kernel learning - MKL) models, we assessed the prognostic value of various clinical and MRI measures for disease activity.</AbstractText>Early MS patients (n</i>&... |
2,329,767 | Revisiting the Concept of Recurrence of Primary Central Nervous System Lymphomas After Complete Response to Methotrexate-Based Therapy: Periventricular Reseeding as the Predominant Mechanism of Recurrence. | Understanding patterns of relapse for primary central nervous system lymphoma (PCNSL) may inform mechanisms of recurrence and optimal consolidation strategies. In this study, we report patterns of relapse among patients with PCNSL who achieved a complete response to high-dose methotrexate (HD-MTX)-based chemotherapy wi... |
2,329,768 | [Septo optic dysplasia plus: about a case]. | Septo optic dysplasia plus is a rare disease seen in children. Its diagnosis is radiological, based on brain magnetic resonance imaging (MRI). We report the case of a child aged 2 years and 4 months, with no particular pathological history; who consulted for psychomotor retardation, strabismus and low vision behavior. ... |
2,329,769 | Evaluation of Intracranial Structures of Fetuses With Congenital Heart Defects.<Pagination><StartPage>419</StartPage><EndPage>425</EndPage><MedlinePgn>419-425</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/jum.16049</ELocationID><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE"... | Pulse pressure is the difference between systolic and diastolic blood pressures. <b>Pulse Pressure = Systolic Blood Pressure – Diastolic Blood Pressure.</b> The systolic blood pressure is defined as the maximum pressure experienced in the aorta when the heart contracts and ejects blood into the aorta from the le... |
2,329,770 | Feasibility, Prediction and Association of Right Ventricular Free Wall Longitudinal Strain with 30-Day Mortality in Severe COVID-19 Pneumonia: A Prospective Study. | Introduction: Right ventricular (RV) systolic dysfunction (RVsD) is a common complication of coronavirus infection 2019 disease (COVID-19). The right ventricular free wall longitudinal strain parameter (RV-FWLS) is a powerful predictor of mortality. We explored the performance of RVsD parameters for predicting 30-day m... |
2,329,771 | Effects of an Exercise Program Combining Aerobic and Resistance Training on Protein Expressions of Neurotrophic Factors in Obese Rats Injected with Beta-Amyloid. | In this study, the effects of a 12-week exercise program combining aerobic and resistance training on high-fat diet-induced obese Sprague Dawley (SD) rats after the injection of beta-amyloid into the cerebral ventricle were investigated. Changes in physical fitness, cognitive function, blood levels of beta-amyloid and ... |
2,329,772 | Endogenous Neural Stem Cell Mediated Oligodendrogenesis in the Adult Mammalian Brain. | Oligodendrogenesis is essential for replacing worn-out oligodendrocytes, promoting myelin plasticity, and for myelin repair following a demyelinating injury in the adult mammalian brain. Neural stem cells are an important source of oligodendrocytes in the adult brain; however, there are considerable differences in olig... |
2,329,773 | The Interaction of <i>mTOR</i> and <i>Nrf2</i> in Neurogenesis and Its Implication in Neurodegenerative Diseases. | Neurogenesis occurs in the brain during embryonic development and throughout adulthood. Neurogenesis occurs in the hippocampus and under normal conditions and persists in two regions of the brain-the subgranular zone (SGZ) in the dentate gyrus of the hippocampus and the subventricular zone (SVZ) of the lateral ventricl... |
2,329,774 | Study on Antidepressant Effect and Mechanism of Crocin Mediated by the mTOR Signaling Pathway. | Crocin is a monomer of Chinese traditional herbs extracted from saffron, relieving depression-like behavior. However, its underlying mechanism of action remains unclear. Herein, we explored whether crocin's antidepressant effect depended on the mammalian target of the rapamycin (mTOR) signaling pathway. The model of PC... |
2,329,775 | Pleural and transpulmonary pressures to tailor protective ventilation in children. | This review aims to: (1) describe the rationale of pleural (P<sub>PL</sub>) and transpulmonary (P<sub>L</sub>) pressure measurements in children during mechanical ventilation (MV); (2) discuss its usefulness and limitations as a guide for protective MV; (3) propose future directions for paediatric research. We conducte... |
2,329,776 | Giant Colloid Cyst. | Giant colloid cysts are defined as cysts of more than 3 cm in maximal diameter. Few cases of giant colloid cysts have been reported in the literature. We herein describe a giant colloid cyst. A 15-year-old female presented with headache, blurred vision, and episodic behavioral changes for 3 months. Neurologic... |
2,329,777 | Curcumin analogue BDDD-721 exhibits more potent anticancer effects than curcumin on medulloblastoma by targeting Shh/Gli1 signaling pathway. | Medulloblastoma (MB) is a malignant tumor in the fourth ventricle of children. The clinical treatment is mainly surgical resection combined with radiotherapy and chemotherapy, but the curative effect is not ideal, and the 3-year survival rate is very low. Previous study confirmed that curcumin attenuated the proliferat... |
2,329,778 | Brain Damage-linked ATP Promotes P2X7 Receptors Mediated Pineal N-acetylserotonin Release. | The pineal gland is a key player in surveillance and defense responses. In healthy conditions, nocturnal circulating melatonin (MEL) impairs the rolling and adhesion of leukocytes to the endothelial layer. Fungi, bacteria, and pro-inflammatory cytokines block nocturnal pineal MEL synthesis, facilitating leukocyte migra... |
2,329,779 | Bilateral Dacryoadenitis and Central Nervous System Involvement in a Child With Kimura Disease. | Kimura's disease (KD) is a systemic inflammatory condition characterized by lymphadenopathy and subcutaneous nodules in the head and neck region. The lesions have a distinctive histopathological pattern formed by follicular hyperplasia, eosinophilic infiltrates, fibrosis, and vessel proliferation. The disease may occur... |
2,329,780 | Neuropathy-associated Fars2 deficiency affects neuronal development and potentiates neuronal apoptosis by impairing mitochondrial function. | Neurodegenerative diseases encompass an extensive and heterogeneous group of nervous system disorders which are characterized by progressive degeneration and death of neurons. Many lines of evidence suggest the participation of mitochondria dysfunction in these diseases. Mitochondrial phenylalanyl-tRNA synthetase, enco... |
2,329,781 | Spatial and temporal variation of routine parameters: pitfalls in the cerebrospinal fluid analysis in central nervous system infections. | The cerebrospinal fluid (CSF) space is convoluted. CSF flow oscillates with a net flow from the ventricles towards the cerebral and spinal subarachnoid space. This flow is influenced by heartbeats, breath, head or body movements as well as the activity of the ciliated epithelium of the plexus and ventricular ependyma. ... |
2,329,782 | [Effect mechanism of blistering moxibustion on visceral hypersensitivity of irritable bowel syndrome in mice based on 5-HT signal pathway]. | <b>目的：</b>观察天灸法对内脏高敏性肠易激综合征（IBS）小鼠结肠组织5-羟色胺（5-HT）及其受体蛋... |
2,329,783 | Magnetic resonance imaging features of isolated periventricular heterotopia in pediatric epilepsy: a comparative study. | Periventricular nodular heterotopia is a neurodevelopmental disorder in which neurons fail to migrate to the cortical surface, forming discrete areas of grey matter adjacent to the lateral ventricles. Given that periventricular nodular heterotopia is seen as an incidental finding in patients without epilepsy, causality... |
2,329,784 | Analysis of L1CAM gene mutation and imaging appearance in three Chinese families with L1 syndrome: Three case reports. | The molecular mutations of the L1CAM gene and the imaging appearances of four fetuses with L1 syndrome from three independent Chinese families with a history of hydrocephalus were reported in this study. Two of the three are novel L1CAM variants.</AbstractText>Results of clinical and imaging examinations of three Chine... |
2,329,785 | Long-term quality of life after ETV or ETV with consecutive VP shunt placement in hydrocephalic pediatric patients. | Endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunting are well-established treatments of obstructive hydrocephalus (HCP) in adult and pediatric patients. However, there is a lack of data with regard to the quality of life (QoL) of these patients during long-term follow-up METHODS: Inclusion criteria ... |
2,329,786 | Effects of Spring Warming on Seasonal Neuroendocrinology and Activation of the Reproductive Axis in Hibernating Arctic Ground Squirrels. | Many animals adjust the timing of seasonal events, such as reproduction, molt, migration, and hibernation, in response to interannual variation and directional climate-driven changes in temperature. However, the mechanisms by which temperature influences seasonal timing are relatively under-explored. Seasonal timing in... |
2,329,787 | An unusual origin of a papillary muscle of the right ventricle.<Pagination><StartPage>147</StartPage><EndPage>150</EndPage><MedlinePgn>147-150</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.morpho.2022.03.002</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S1286-0115(22)00030-3</ELocation... | Knowledge of anatomical variations of the heart are important to cardiac surgeons, cardiologists, and radiologist. During routine dissection of a 77-year-old male cadaver, we observed an unusual origin of a papillary muscle of the right ventricle arising from the atrioventricular aspect of the moderator band. This papi... |
2,329,788 | [Clinicopathological features of polymorphous low-grade neuroepithelial tumor of the young]. | <b>Objective:</b> To investigate the clinicopathological features and differential diagnosis of polymorphous low-grade neuroepithelial tumor of the young (PLNTY). <b>Methods:</b> Five cases of PLNTY diagnosed at the First Affiliated Hospital and Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China fr... |
2,329,789 | Single-Center Retrospective Analysis of Risk Factors for Hydrocephalus After Lateral Ventricular Tumor Resection. | There is no general consensus on the placement of preoperative and intraoperative external ventricular drainage (EVD) in patients with lateral ventricular tumors (LVTs). The aim of this study was to identify the predictors of postoperative acute and persistent hydrocephalus need for postoperative cerebrospinal fluid (C... |
2,329,790 | Magnetic resonance imaging measures of brain volumes across the EXPEDITION trials in mild and moderate Alzheimer's disease dementia. | Solanezumab is a monoclonal antibody that preferentially binds soluble amyloid beta and promotes its clearance from the brain. The aim of this post hoc analysis was to assess the effect of low-dose solanezumab (400 mg) on global brain volume measures in patients with mild or moderate Alzheimer's disease (AD) dementia q... |
2,329,791 | Unraveling the interplay between dipeptidyl peptidase 4 and the renin-angiotensin system in heart failure.<Pagination><StartPage>120757</StartPage><MedlinePgn>120757</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.lfs.2022.120757</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0024-3205(2... | Aortic regurgitation (AR), also known as aortic insufficiency, is a form of valvular heart disease in which the integrity of the aortic valve is compromised and leads to inadequate closure of the valve leaflets. A normal aortic valve is comprised of three semilunar cusps that attach to the aortic wall. Loss of function... |
2,329,792 | First Cardiac Magnetic Resonance Experience in Bangladesh: A Case of Arrhythmogenic Right Ventricular Dysplasia.<Pagination><StartPage>876</StartPage><EndPage>881</EndPage><MedlinePgn>876-881</MedlinePgn></Pagination><Abstract><AbstractText>Arrhythmogenic right ventricular dysplasia (ARVD) is a progressive degeneration... | Arrhythmogenic right ventricular dysplasia (ARVD) is a progressive degeneration and replacement of the right ventricular (RV) myocardial tissue by fat and fibrosis and produce clinical condition. Desmosome gene mutations are only the causative state for ARVD hereditary disorder. The arrhythmogenic right ventricular car... |
2,329,793 | Effects of Cranioplasty on Contralateral Subdural Effusion After Decompressive Craniectomy: A Literature Review.<Pagination><StartPage>147</StartPage><EndPage>153</EndPage><MedlinePgn>147-153</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.wneu.2022.06.117</ELocationID><ELocationID EIdType="pi... | Contralateral subdural effusion (CSE) after decompressive craniectomy (CSEDC) is occasionally observed. Cranioplasty is routinely performed for reconstruction and has recently been associated with improving contralateral subdural effusion. We sought to systematically review all available literature and evaluate the eff... |
2,329,794 | First-pass perfusion cardiovascular magnetic resonance parameters as surrogate markers for left ventricular diastolic dysfunction: a validation against cardiac catheterization.<Pagination><StartPage>8131</StartPage><EndPage>8139</EndPage><MedlinePgn>8131-8139</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN=... | This study's objective was to investigate obtaining high-resolution micro-computed tomography (CT) imaging of the injected arterial circulation of the brains of the dogfish (Squalus acanthias), American bullfrog (Rana catesbeiana), and green iguana (Iguana iguana). No micro-CT images of the arterial morphology of the b... |
2,329,795 | Early prediction of failure to progress in single ventricle palliation: A step toward personalizing care for severe congenital heart disease.<Pagination><StartPage>1268</StartPage><EndPage>1276</EndPage><MedlinePgn>1268-1276</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.healun.2022.06.002</E... | Advances in surgical technique and medical surveillance have improved outcomes of single ventricle (SV) palliation, particularly during the first interstage period. However, there remains a considerable mortality risk beyond this period.</AbstractText>Patients born between January 2004 and December 2011 who required SV... |
2,329,796 | Isolation of Adult Mouse Neural Stem Cells and Assessment of Self-Renewal by ELDA. | The generation of new neurons in the adult brain throughout life is integral to brain plasticity and repair. Adult neural stem cells (aNSCs), present in the subventricular zone (SVZ) of the lateral ventricle wall and the subgranular zone (SGZ) of the hippocampal dentate gyrus, divide symmetrically or asymmetrically to ... |
2,329,797 | MRI abnormalities in a severe cognitive impairment mimicking a forebrain lesion in a geriatric dog. | Canine Cognitive Dysfunction is a neurological condition, that causes dogs to experience a wide variety of clinical signs. On rare occasions the symptoms may be unusual and severe, therefore they reminiscent of another disease. In this case report a 16 year and 8-month-old intact female poodle presented with circling, ... |
2,329,798 | Hypothesis: By-products of vascular disruption carried in the CSF affect prenatal brain development. | Prenatal CNS disruptions can be associated with physically separate findings. Examples include cognitive issues in septo-optic dysplasia and sporadic and WNT1-related unilateral cerebellar hypoplasia, and physical findings such as thinning of the corpus callosum, ventriculomegaly, hippocampal abnormalities, olfactory t... |
2,329,799 | Application of Light-Sheet Mesoscopy to Image Host-Pathogen Interactions in Intact Organs. | Human African Trypanosomiasis (HAT) is a disease caused by the extracellular parasite <i>Trypanosoma brucei</i> that affects the central nervous system (CNS) during the chronic stage of the infection, inducing neuroinflammation, coma, and death if left untreated. However, little is known about the structural change hap... |
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