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2,329,600 | Factors Associated With Gastrostomy Tube Complications in Infants With Congenital Heart Disease.<Pagination><StartPage>273</StartPage><EndPage>279</EndPage><MedlinePgn>273-279</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jss.2022.07.022</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0... | Atrioventricular (AV) junction is the area separating atria and the ventricles of the heart. Specifically, when talking about the AV junction, the focus is put more on its contents, the AV node and the nonbranching bundle of His. The AV junction plays a role in the pathology including atrioventricular nodal re-entrant ... |
2,329,601 | Transtemporal brain contrast-enhanced ultrasound in children: preliminary experience in patients without neurological disorders. | To evaluate the use of transtemporal brain contrast-enhanced ultrasound (CEUS) to assess cerebral blood perfusion in a cohort of children without neurological disorders.</AbstractText>We included pediatric patients who were undergoing a clinically-indicated CEUS study. Brain scans were performed with a Siemens Sequoia ... |
2,329,602 | Strain-dependent stress relaxation behavior of healthy right ventricular free wall. | The increasing evidence of stress-strain hysteresis in large animal or human myocardium calls for extensive characterizations of the passive viscoelastic behavior of the myocardium. Several recent studies have investigated and modeled the viscoelasticity of the left ventricle while the right ventricle (RV) viscoelastic... |
2,329,603 | Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37. | Topoisomerase IIA (TOP2a) has traditionally been known as an important nuclear enzyme that resolves entanglements and relieves torsional stress of DNA double strands. However, its function in genomic transcriptional regulation remains largely unknown, especially during adult neurogenesis. Here, we show that TOP2a is pr... |
2,329,604 | Minimally Invasive Resection of Intraventricular Pilocytic Astrocytoma Using the Aurora Surgiscope in an Adult Patient: Technical Note. | Pilocytic astrocytomas account for approximately 5%-6% of all gliomas and are most commonly diagnosed between the ages of 8 and 13 years. Although they may occur throughout the neuraxis, approximately two thirds arise from the cerebellum and optic pathway. Other locations of origin include midline structures such as th... |
2,329,605 | SETD4 cells contribute to brain development and maintain adult stem cell reservoir for neurogenesis. | Cellular quiescence facilitates maintenance of neural stem cells (NSCs) and their subsequent regenerative functions in response to brain injury and aging. However, the specification and maintenance of NSCs in quiescence from embryo to adulthood remain largely unclear. Here, using Set domain-containing protein 4 (SETD4)... |
2,329,606 | Brain morphological alterations and their correlation to tumor differentiation and duration in patients with lung cancer after platinum chemotherapy. | Chemotherapy-related brain impairments and changes can occur in patients with lung cancer after platinum chemotherapy and have a substantial impact on survivors' quality of life. Therefore, it is necessary to understand the brain neuropathological alterations and response mechanisms to provide a theoretical basis for r... |
2,329,607 | Epidermal Growth Factor Receptor Kinase Inhibitor Ameliorates β-Amyloid Oligomer-Induced Alzheimer Disease in Swiss Albino Mice. | Alzheimer's disease (AD) is one of the major neurodegenerative disorders, and its incidence increases globally every year. Currently, available AD drugs symptomatically treat AD with multiple adverse effects. Gefitinib (GE) is an epidermal growth factor receptor (EGFR) kinase inhibitor. EGFR is the preferred target for... |
2,329,608 | Epilepsy in Pediatric Patients-Evaluation of Brain Structures' Volume Using VolBrain Software. | Epilepsy is one of the most frequent serious brain disorders. Approximately 30,000 of the 150,000 children and adolescents who experience unprovoked seizures are diagnosed with epilepsy each year. Magnetic resonance imaging is the method of choice in diagnosing and monitoring patients with this condition. However, one ... |
2,329,609 | Using DeepLabCut as a Real-Time and Markerless Tool for Cardiac Physiology Assessment in Zebrafish. | DeepLabCut (DLC) is a deep learning-based tool initially invented for markerless pose estimation in mammals. In this study, we explored the possibility of adopting this tool for conducting markerless cardiac physiology assessment in an important aquatic toxicology model of zebrafish (<i>Danio rerio</i>). Initially, hig... |
2,329,610 | Impact and Modifiers of Ventricular Pacing in Patients With Single Ventricle Circulation.<Pagination><StartPage>902</StartPage><EndPage>914</EndPage><MedlinePgn>902-914</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jacc.2022.05.053</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0735-10... | This study aims to clarify the relation of development of aortopulmonary collateral arteries (APCs) with anatomical sub-types and the shunt types at Norwood procedure in patients with hypoplastic left heart syndrome (HLHS). A total of 140 patients with HLHS who completed 3 staged palliation between 2003 and 2019 were i... |
2,329,611 | Thalamic nuclei atrophy at high and heterogenous rates during cognitively unimpaired human aging. | The thalamus is a central integration structure in the brain, receiving and distributing information among the cerebral cortex, subcortical structures, and the peripheral nervous system. Prior studies clearly show that the thalamus atrophies in cognitively unimpaired aging. However, the thalamus is comprised of multipl... |
2,329,612 | Accuracy and reliability of magnetic resonance imaging in the diagnosis of idiopathic intracranial hypertension. | To determine the diagnostic utility of brain magnetic resonance imaging (MRI) findings in patients with idiopathic intracranial hypertension (IIH) and to investigate the significance of evaluating radiological findings together with neurological and ophthalmological data in the diagnosis of IIH.</AbstractText>All conse... |
2,329,613 | Diagnostic approach to fetal ventriculomegaly. | Ventriculomegaly (VM) is defined as an enlargement of the lateral ventricles of the developing fetal brain. The diagnosis is easily made by measuring the lateral ventricle width at the level of the atrium, which is normally <10 mm. VM is defined as mild when the atrial width is 10-12 mm, moderate 12-15
... |
2,329,614 | Aortic Arch Phenotypes in Double Outlet Right Ventricle (DORV)-Implications for Surgery and Multi-Modal Imaging. | Abnormal aortic arches (AAAs) cover a spectrum of malformations, including abnormal laterality, branching patterns, and flow-limiting narrowing, which themselves vary from tubular hypoplasia, through discrete coarctation, to complete interruption of the arch. Neonatal surgery within the first days of life is necessary ... |
2,329,615 | Valve Endothelial Cell Exposure to High Levels of Flow Oscillations Exacerbates Valve Interstitial Cell Calcification.<ELocationID EIdType="pii" ValidYN="Y">393</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3390/bioengineering9080393</ELocationID><Abstract><AbstractText>The aortic valve facilitates unidirectio... | The aortic valve facilitates unidirectional blood flow to the systemic circulation between the left cardiac ventricle and the aorta. The valve's biomechanical function relies on thin leaflets to adequately open and close over the cardiac cycle. A monolayer of valve endothelial cells (VECs) resides on the outer surface ... |
2,329,616 | Evaluation of biventricular longitudinal myocardial function in normal fetuses at different gestational ages using ultrasonic velocity vector imaging. | This study aimed to evaluate biventricular myocardial function and biventricular longitudinal global myocardial function of fetuses at different gestational weeks using ultrasonic velocity vector imaging.</AbstractText>A total of 127 pregnant women were enrolled and divided into five groups according to the gestational... |
2,329,617 | Cardiovocal Syndrome Associated With Idiopathic Pulmonary Arterial Hypertension: A Case Report and Literature Review. | Cardiovocal syndrome is left recurrent laryngeal nerve palsy associated with cardiovascular disease. Herein, we report a rare case of left recurrent laryngeal nerve palsy caused by idiopathic pulmonary arterial hypertension. A 40-year-old woman diagnosed with idiopathic pulmonary arterial hypertension was referred to o... |
2,329,618 | Automation of ischemic myocardial scar detection in cardiac magnetic resonance imaging of the left ventricle using machine learning. | Machine learning techniques can be applied to cardiac magnetic resonance imaging (CMR) scans in order to differentiate patients with and without ischemic myocardial scarring (IMS). However, processing the image data in the CMR scans requires manual work that takes a significant amount of time and expertise. We propose ... |
2,329,619 | DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential. | Cells with latent stem ability can contribute to mammalian tissue regeneration after damage. Whether the central nervous system (CNS) harbors such cells remains controversial. Here, we report that DNGR-1 lineage tracing in mice identifies an ependymal cell subset, wherein resides latent regenerative potential. We demon... |
2,329,620 | Cavum septum pellucidum nomogram during the second trimester of pregnancy. | This study aimed to determine cavum septum pellucidum (CSP) nomogram values between 15-28 weeks of gestation. Routine biometric measurements and CSP width were measured by transabdominal ultrasonography in 6042 structurally normal foetuses between 15-28 weeks of gestation. Distribution of CSP width by the... |
2,329,621 | Cardiac efficiency and Starling's Law of the Heart.<Pagination><StartPage>4265</StartPage><EndPage>4285</EndPage><MedlinePgn>4265-4285</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1113/JP283632</ELocationID><Abstract><AbstractText>The formulation by Starling of The Law of the Heart states that 'th... | The formulation by Starling of The Law of the Heart states that 'the [mechanical] energy of contraction, however measured, is a function of the length of the muscle fibre'. Starling later also stated that 'the oxygen consumption of the isolated heart … is determined by its diastolic volume, and therefore by the ... |
2,329,622 | Ocular Manifestations Leading to a Diagnosis of Joubert Syndrome Related Disorder. | Joubert syndrome is an inherited disorder of rare occurrence usually presenting as developmental delay, hypotonia, hyperpnea and ataxia. The diagnosis is confirmed by characteristic findings in neuroimaging. Involvement of ocular, renal and hepatic systems can be present. Joubert syndrome presenting first to an ophthal... |
2,329,623 | Association of complement component 4 with neuroimmune abnormalities in the subventricular zone in schizophrenia and autism spectrum disorders. | An early inflammatory insult is the most recognized risk factor associated with neurodevelopmental psychiatric disorders, even more so than genetic variants. Notably, complement component 4 (C4), a molecule involved in inflammatory responses, has been strongly associated with schizophrenia (SZ) and its role in other ne... |
2,329,624 | Morphological evaluation of the normal and hydrocephalic third ventricle on cranial magnetic resonance imaging in children: a retrospective study. | Third ventricle morphological changes reflect changes in the ventricular system in pediatric hydrocephalus, so visual inspection of the third ventricle shape is standard practice. However, normal pediatric reference data are not available.</AbstractText>To investigate both the normal development of the third ventricle ... |
2,329,625 | Prenatal androgen treatment impairs the suprachiasmatic nucleus arginine-vasopressin to kisspeptin neuron circuit in female mice. | Polycystic ovary syndrome (PCOS) is associated with elevated androgen and luteinizing hormone (LH) secretion and with oligo/anovulation. Evidence indicates that elevated androgens impair sex steroid hormone feedback regulation of pulsatile LH secretion. Hyperandrogenemia in PCOS may also disrupt the preovulatory LH sur... |
2,329,626 | Dyke-Davidoff-Masson syndrome: A rare case of hemiatrophy of brain-Case report from Nepal. | Dyke-Davidoff-Masson syndrome (DDMS) is a rare neurological disorder that results from brain injury during intrauterine or early years of life. Prominent cortical sulci, dilated lateral ventricles, cerebral hemiatrophy, hyperpneumatization of the sinus, and compensatory hypertrophy of the skull are the characteristic f... |
2,329,627 | Association of fetal hydrocephalus with other embryological anomalies: A prenatal ultrasound-based study. | To determine the incidence of fetal hydrocephalus in pregnant women and to identify the association of fetal hydrocephalus with other embryological anomalies.</AbstractText>This comparative cross-sectional study was conducted on 36 pregnant women at a private ultrasound clinic in Karachi over a period of eight months. ... |
2,329,628 | Predicting Hematoma Expansion after Spontaneous Intracranial Hemorrhage Through a Radiomics Based Model. | Intracranial hemorrhage (ICH) is characterized as bleeding into the brain tissue, intracranial space, and ventricles and is the second most disabling form of stroke. Hematoma expansion (HE) following ICH has been correlated with significant neurological decline and death. For early detection of patients at risk, deep l... |
2,329,629 | Living on a Thread: A Case of Critical Left Main Coronary Artery Disease With an Unusual Presentation.<Pagination><StartPage>e26942</StartPage><MedlinePgn>e26942</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">e26942</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.7759/cureus.26942</ELocationID><... | The left main disease is significant stenosis of the left coronary artery, which is responsible of supplying blood to a major portion of the left ventricle. In this report, we describe a unique case of critical left main disease with a special clinical presentation. A 66-year-old male with insignificant past medical hi... |
2,329,630 | Detection of Cardiac Functions of Fetus with Diabetic Metabolic Disease through PEG-PCLNano Micelle and Ultrasound Technique.<Pagination><StartPage>24</StartPage><EndPage>33</EndPage><MedlinePgn>24-33</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.14715/cmb/2022.68.3.4</ELocationID><Abstract><Abstra... | Atrioventricular reciprocating tachycardia (AVRT) is a macroreentrant tachycardia that needs an accessory pathway to bypass the regular conduction system. Atrioventricular reentry tachycardia has a circuit that consists of two different pathways consisted of the regular conduction system through the AV node and an... |
2,329,631 | Molecular neurobiological markers in the onset of sodium appetite. | Sodium appetite is a motivational state involving homeostatic behavior, seeking the ingest of salty substances after sodium loss. There is a temporal dissociation between sodium depletion (SD) and the appearance of sodium appetite. However, the responsible mechanisms for this delay remain poorly elucidated. In the pres... |
2,329,632 | A hidden infection: Racemose neurocysticercosis causing hydrocephalus; a case report. | Neurocysticercosis (NCC) is the most common helminthic central nervous system infection (CNS) in the Western hemisphere and the most common cause of acquired epilepsy worldwide. Due to its relatively prolonged latent period and clinical similarity to other infectious diseases - including bacterial or viral meningitis a... |
2,329,633 | Supratentorial extra-axial RELA fusion-positive ependymoma misdiagnosed as meningioma by intraoperative histological and cytological examinations: a case report. | Dura-attached supratentorial extra-axial ependymoma is a very rare type of tumor, with only nine reported cases. Preoperative diagnosis of dura-attached supratentorial extra-axial ependymoma is difficult and often radiologically misdiagnosed as a meningioma. We report a case of dura-attached supratentorial extra-axial ... |
2,329,634 | Neuroblast migration along cellular substrates in the developing porcine brain. | In the past decade it has become evident that neuroblasts continue to supply the human cortex with interneurons via unique migratory streams shortly following birth. Owing to the size of the human brain, these newborn neurons must migrate long distances through complex cellular landscapes to reach their final locations... |
2,329,635 | Spectrum of qualitative and quantitative imaging of pilomyxoid, intermediate pilomyxoid and pilocytic astrocytomas in relation to their genetic alterations. | Pilomyxoid astrocytomas (PMA) are pediatric brain tumors predominantly located in the suprasellar region, third ventricle and posterior fossa, which are considered to be more clinically aggressive than pilocytic astrocytomas (PA). Another entity, intermediate pilomyxoid tumors (IPT), exists within the spectrum of piloc... |
2,329,636 | Immune Microenvironment and Lineage Tracing Help to Decipher Rosette-Forming Glioneuronal Tumors: A Multi-Omics Analysis. | Rosette-forming glioneuronal tumors (RGNT) are rare low-grade primary central nervous system (CNS) tumors. The methylation class (MC) RGNT (MC-RGNT) delineates RGNT from other neurocytic CNS tumors with similar histological features. We performed a comprehensive molecular analysis including whole-exome sequencing, RNAs... |
2,329,637 | A Case Report of Severe Posterior Reversible Encephalopathy Syndrome Due to Accelerated Hypertension in a Young Patient. | Posterior reversible encephalopathy syndrome (PRES) refers to white matter vasogenic edema primarily affecting the brain's posterior occipital and parietal lobes, causing acute neurological symptoms like headaches, visual symptoms, seizures, and altered mental status. We present the case of a 32-year-old male with unco... |
2,329,638 | Duct-like diverticulum at the base of third ventricle tumors: a morphological signature diagnostic of papillary craniopharyngioma. | This study describes and characterizes a narrow, hollow tubular structure, termed as duct-like diverticulum (DV), found specifically at the basal midline of papillary craniopharyngiomas (PCPs) located within the third ventricle (3V). The presence of this structure was systematically investigated on autopsy studies and ... |
2,329,639 | The neurodevelopmental gene MSANTD2 belongs to a gene family formed by recurrent molecular domestication of Harbinger transposons at the base of vertebrates. | The formation of new genes is a major source of organism evolutionary innovation. Beyond their mutational effects, transposable elements can be co-opted by host genomes to form different types of sequences including novel genes, through a mechanism named molecular domestication.We report the formation of four genes thr... |
2,329,640 | Cross-sectional reference values of cerebral ventricle for Chinese neonates born at 25-41 weeks of gestation. | To establish the cross-sectional reference values of cerebral ventricular size for the Chinese newborns by the most correlated explanatory variables. The anterior horn width (AHW), thalamo-occipital distance (TOD), and ventricular index (VI) were collected prospectively from 1- to 7-day neonates without potential neuro... |
2,329,641 | Craniopharyngiomas: Surgery and Radiotherapy. | Taking into account the benign nature of craniopharyngiomas, the main method of treatment is the resection of the tumor. However, the tendency of these tumors to invade critical structures (such as optic pathways, the hypothalamic-pituitary system, the Willis circle vessels) often limits the possibility of a radical su... |
2,329,642 | Hydrocephalus associated to posterior fossa tumor-like sarcoidosis: A case report and literature review. | Intracranial inflammatory pseudotumors (IIPT) are one of the differential diagnosis for the central nervous system (CNS) tumors. They represent a rare condition that may mimic clinically and radiologically intracranial tumors and induce their complications. Among their etiologies, neurosarcoidosis is one of t... |
2,329,643 | Synergistic antidepressant effects of citalopram and SB-334867 in the REM sleep-deprived mice: Possible role of BDNF. | This study was done to evaluate the effect of co-treatment of orexin agents along with citalopram on the modulation of depression-like behavior and the expression of BDNF in the prefrontal cortex (PFC) of sleep-deprived male mice. A sleep deprivation model was performed in which rapid eye movement (REM) sleep was compl... |
2,329,644 | Correlations between sleep disturbance and brain structures associated with neurodegeneration in the National Alzheimer's Coordinating Center Uniform Data Set. | This study aimed to 1) determine the association between sleep disturbance and brain structure volumes, 2) the moderation effect of apolipoprotein ε4 genotype on sleep disturbance and brain structures, and 3) the moderation effect of sleep disturbance on cognitive status and regional brain volumes. Using the Nati... |
2,329,645 | Involvement of the ERK signaling pathways in the NAc in propofol-seeking behavior induced by cues in rats. | Propofol, an intravenous short-acting anesthetic, has the potential to induce craving and relapse. Accumulated evidence demonstrates that extracellular signal-regulated kinase (ERK) plays an essential role in drug reward and relapse. In the previous study, we demonstrated that the ERK signaling pathways in the Nucleus ... |
2,329,646 | Endoscopic Endonasal Eustachian Tube Obliteration as a Treatment for Tension Pneumocephalus After Translabyrinthine Resection of Vestibular Schwannoma. | Cerebrospinal fluid leak and pneumocephalus are rare but potentially devastating complications associated with translabyrinthine resection of cerebellopontine angle masses. Persistent pneumocephalus despite proximal eustachian tube (ET) obliteration is rare. We describe, to our knowledge, the first report of successful... |
2,329,647 | Probing Caffeine Administration as a Medical Management for Hydrocephalus: An Experimental Study. | Hydrocephalus is currently managed by cerebrospinal fluid diversion from the cerebral ventricles to other body sites, but this is complicated by obstruction and infection in young infants, thus adding to morbidity and mortality. Studies have reported caffeine to be a pleiotropic neuroprotective drug in the developing b... |
2,329,648 | Microsurgical Management of Fourth Ventricle Lesions Via the Median Suboccipital Keyhole Telovelar Approach. | In this 2-year retrospective analysis, 13 patients with fourth ventricle lesions who underwent microsurgical resection via the midline suboccipital keyhole telovelar approach were analyzed. This is the first study to investigate the surgical outcome and complications of using this approach to resect various types of le... |
2,329,649 | Detection of left ventricular wall motion abnormalities from volume rendering of 4DCT cardiac angiograms using deep learning. | The presence of left ventricular (LV) wall motion abnormalities (WMA) is an independent indicator of adverse cardiovascular events in patients with cardiovascular diseases. We develop and evaluate the ability to detect cardiac wall motion abnormalities (WMA) from dynamic volume renderings (VR) of clinical 4D computed t... |
2,329,650 | Grade III solitary fibrous tumor/hemangiopericytoma: An enthralling intracranial tumor-A case report and literature review. | Hemangiopericytomas account for less than 1% of all intracranial tumors. In 2016, World Health Organization (WHO) unified the two terms into a single medical condition known as solitary fibrous tumor/hemangiopericytoma (SFT/HPC). Our patient is an 80-year-old woman with a past medical history of sick sinus syndrome sta... |
2,329,651 | Posterior Fossa Calcifying Pseudoneoplasm of the Neuraxis (CAPNON): Presentation of Three Surgical Cases. | Calcifying pseudoneoplasm of the neuraxis (CAPNON) is an extremely rare entity with fewer than 150 cases reported in the literature and mostly with a supratentorial or spinal location. Posterior fossa CAPNON has been reported scarcely, and association with perilesional edema is a topic not yet approached which might pl... |
2,329,652 | Implications of Transfusion in Adults with Congenital Heart Disease Undergoing Cardiac Surgery.<Pagination><StartPage>218</StartPage><EndPage>227</EndPage><MedlinePgn>218-227</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s00246-022-02981-2</ELocationID><Abstract><AbstractText>The number of adu... | The number of adults with congenital heart disease (CHD) requiring cardiovascular (CV) surgery is increasing rapidly in today's era. We hypothesized that exposure to perioperative blood products is associated with worse outcomes in adults. All adults (≥ 18 years old) undergoing CV surgery with Cardio... |
2,329,653 | Correction to: Basal Recess in Third Ventricle Tumors: A Pathological Feature Defining a Clinical-Topographical Subpopulation of Papillary Craniopharyngiomas.<Pagination><StartPage>1042</StartPage><MedlinePgn>1042</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/jnen/nlac072</ELocationID><AuthorL... | Transependymal flow (TEF) of CSF, often delineated as T2-weighted hyperintensity adjacent to the lateral ventricles on MRI, is a known imaging finding, usually in the setting of CSF flow disturbances. Specific radiological features of TEF and their relationships with clinical markers of hydrocephalus and underlying dis... |
2,329,654 | Drugs and Endogenous Factors as Protagonists in Neurogenic Stimulation. | Neurogenesis is a biological process characterized by new neurons formation from stem cells. For decades, it was believed that neurons only multiplied during development and in the postnatal period but the discovery of neural stem cells (NSCs) in mature brain promoted a revolution in neuroscience field. In mammals, neu... |
2,329,655 | Is the Choroid Plexus Needed? | Choroid plexectomy was first performed around 1910. Later, the technique evolved into subtotal choroid plexus cauterization (CPC) but was largely abandoned following the invention of the ventriculoperitoneal shunt. Over time, with improved understanding of the pathophysiology of hydrocephalus and improvement in endosco... |
2,329,656 | Differential vulnerability of thalamic nuclei in multiple sclerosis. | Investigating differential vulnerability of thalamic nuclei in multiple sclerosis (MS).</AbstractText>In a secondary analysis of prospectively collected datasets, we pooled 136 patients with MS or clinically isolated syndrome and 71 healthy controls all scanned with conventional 3D-T1 and white-matter-nulled magnetizat... |
2,329,657 | [Clinical characteristics and literature review of 12 cases of granulosa cell tumor of head and neck]. | <b>Objective:</b>To investigate the clinical and pathological features, treatment, prognostic and its influence factors of granulosa cell tumor of head and neck. <b>Methods:</b>The clinical medical records of 12 patients with head and neck granulosa cell tumor confirmed by pathology for diagnosis and treatment in Beiji... |
2,329,658 | Organization of the ventricular zone of the cerebellum. | The roof of the fourth ventricle (4V) is located on the ventral part of the cerebellum, a region with abundant vascularization and cell heterogeneity that includes tanycyte-like cells that define a peculiar glial niche known as ventromedial cord. This cord is composed of a group of biciliated cells that run along the m... |
2,329,659 | The effects of mango leaf extract during adolescence and adulthood in a rat model of schizophrenia. | There is evidence that in schizophrenia, imbalances in inflammatory and oxidative processes occur during pregnancy and in the early postnatal period, generating interest in the potential therapeutic efficacy of anti-inflammatory and antioxidant compounds. Mangiferin is a polyphenolic compound abundant in the leaves of ... |
2,329,660 | How to Optimize ECLS Results beyond Ventricular Unloading: From ECMO to CentriMag<sup>®</sup> eVAD. | CentriMag<sup>®</sup> extracorporeal VAD support could represent a more physiological choice than conventional ECMO in primary cardiogenic shock. We therefore evaluated the outcome of patients with primary cardiogenic shock who were supported with CentriMag<sup>®</sup> extracorporeal VAD implantation versus c... |
2,329,661 | Right Cortical Infarction and a Reduction in Putamen Volume May Be Correlated with Empathy in Patients after Subacute Ischemic Stroke-A Multimodal Magnetic Resonance Imaging Study. | Empathy has not been well studied in patients following ischemic stroke. We aimed to evaluate the relationships of multimodal neuroimaging parameters with the impairment of empathy in patients who had experienced subacute ischemic stroke. Patients who had experienced a first-event acute ischemic stroke were recruited, ... |
2,329,662 | Regulation of APD and Force by the Na<sup>+</sup>/Ca<sup>2+</sup> Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue. | The physiological importance of NCX in human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is not well characterized but may depend on the relative strength of the current, compared to adult cardiomyocytes, and on the exact spatial arrangement of proteins involved in Ca2+ extrusion. Here, we determin... |
2,329,663 | Hydrocephalus in <i>Nfix<sup>-/-</sup></i> Mice Is Underpinned by Changes in Ependymal Cell Physiology. | Nuclear factor one X (NFIX) is a transcription factor required for normal ependymal development. Constitutive loss of <i>Nfix</i> in mice (<i>Nfix<sup>-/-</sup></i>) is associated with hydrocephalus and sloughing of the dorsal ependyma within the lateral ventricles. Previous studies have implicated NFIX in the transcri... |
2,329,664 | Duct-like Recess in the Infundibular Portion of Third Ventricle Craniopharyngiomas: An MRI Sign Identifying the Papillary Type. | Papillary craniopharyngiomas (PCPs) are particularly challenging lesions requiring accurate diagnosis to plan the best therapy. Our aim was to define a narrow duct-like recess identified on MR imaging at the base of papillary craniopharyngiomas with a strict third ventricle location.</AbstractText>A duct-like recess at... |
2,329,665 | Atypical clinical presentation of glioblastoma mimicking autoimmune meningitis in an adult. | Glioblastoma (GBM) is the most malignant type of glial tumor associated with a very unfavorable prognosis. Typical radiological features of GBM include the presence of a tumor with irregular contrast-enhancing margins and central necrosis surrounded by a wide area of vasogenic edema. Here, we presented an atypical clin... |
2,329,666 | Costs of pediatric hydrocephalus treatment for the Brazilian public health system in the Northeast of Brazil. | To estimate the costs of the surgical treatment of pediatric hydrocephalus, specifically ventriculoperitoneal shunt (VPS) and endoscopic third ventriculostomy (ETV), for the Brazilian public health system (SUS).</AbstractText>Retrospective cohort study of health records of patients < 14 years of a... |
2,329,667 | Tax1 banding protein 1 exacerbates heart failure in mice by activating ITCH-P73-BNIP3-mediated cardiomyocyte apoptosis.<Pagination><StartPage>2562</StartPage><EndPage>2572</EndPage><MedlinePgn>2562-2572</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/s41401-022-00950-2</ELocationID><Abstract><Ab... | Tax1 banding protein 1 (Tax1bp1) was originally identified as an NF-κB regulatory protein that participated in inflammatory, antiviral and innate immune processes. Tax1bp1 also functions as an autophagy receptor that plays a role in autophagy. Our previous study shows that Tax1bp1 protects against cardiomyopathy ... |
2,329,668 | Senility and COVID-19 as two possible risk factors for loss of consciousness: A rare case report. | and Importance: More than two years after the start of the COVID-19 pandemic, the world is still grappling with this dilemma. COVID-19 covers a wide range of symptoms. Loss of consciousness (LOC) is a very rare symptom that can threaten a patient's life and blur the prognosis of recovery.</AbstractText>An 89-year-old w... |
2,329,669 | Intra-Parenchymal Cerebellar Metastasis-A Rare Presentation of Castration-Resistant Prostate Cancer. | Intracranial metastases from prostate carcinoma are uncommon and usually manifest as dural secondaries in the supratentorial compartment. We present an unusual case of intra-parenchymal posterior fossa prostatic metastasis in a 61-year-old gentleman and discuss the diagnostic and management challenges involved. A 61-ye... |
2,329,670 | Inducible motor neuron differentiation of human induced pluripotent stem cells in vivo. | Transplantation of neural progenitor cells (NPCs) derived from human-induced pluripotent stem cells (hiPSCs) is one of the promising treatment strategies for motor neuron diseases (MNDs). However, the inefficiency in committed differentiation of NPCs in vivo limits its application. Here, we tried to establish a potenti... |
2,329,671 | Anaesthesia for elite athletes.<Pagination><StartPage>825</StartPage><EndPage>834</EndPage><MedlinePgn>825-834</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1097/EJA.0000000000001719</ELocationID><Abstract><AbstractText Label="BACKGROUND">Sports participation has been growing rapidly since the 1960... | Sports participation has been growing rapidly since the 1960s. Anaesthesiologists are increasingly confronted with athletes in a peri-operative setting. The right choice of type of anaesthesia technique, pain management of injuries, specific physiologic adaptations of the athlete and knowledge of prohibited substances ... |
2,329,672 | [Periventricular changes following hydrocephalus: quantitative MR-based assessment of tissue characteristics]. | To study tissue characteristics of periventricular white matter in patients with open hydrocephalus using DWI MRI and their correlations with CSF flow parameters.</AbstractText>MRI was performed in 55 patients (35 women and 20 men) with open normal pressure hydrocephalus, as well as 16 patients with malignant occlusive... |
2,329,673 | Elevated salivary kynurenic acid levels related to enlarged choroid plexus and severity of clinical phenotypes in treatment-resistant schizophrenia. | Patients with treatment-resistant schizophrenia (TRS) suffer severe, long-term psychotic symptoms and chronic stress. Salivary kynurenic acid (KYNA) and choroid plexus were evidenced to relate to psychological stress. We hypothesized that TRS patients would have higher salivary KYNA levels than patients who respond to ... |
2,329,674 | Investigation of serum adropin levels and its relationship with hypothalamic atrophy in patients with multiple sclerosis. | Adropin is expressed in vascular endothelial cells and regulates nitric oxide (NO) bioavailability by upregulating nitric oxide. In recent years, some studies have revealed its relationship with the pathogenesis of multiple sclerosis (MS). Our aim in this study is to determine serum adropin levels in MS patients and to... |
2,329,675 | Single ventricle: amphibians and human beings.<Pagination><StartPage>643</StartPage><EndPage>646</EndPage><MedlinePgn>643-646</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s12519-022-00595-5</ELocationID><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Angelini</LastName><ForeName>Paol... | Right ventricular (RV) shock, classically characterized by elevated central venous pressure (CVP) with normal to low pulmonary artery (PA) and pulmonary capillary wedge pressures (PCWP), remains a significant cause of morbidity and mortality worldwide if left untreated. Therapies for the treatment of RV ... |
2,329,676 | Characterization of TRPV4-mediated signaling pathways in an optimized human choroid plexus epithelial cell line.<Pagination><StartPage>C1823</StartPage><EndPage>C1842</EndPage><MedlinePgn>C1823-C1842</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1152/ajpcell.00193.2022</ELocationID><Abstract><Abstr... | The objectives of these studies were twofold: <i>1</i>) to characterize the human choroid plexus papilloma (HIBCPP) cell line as a model of the blood-cerebrospinal fluid barrier (BCSFB) via morphology, tightness, and polarization of transporters in choroid plexus epithelia (CPe), and <i>2</i>) to utilize Ussing-style e... |
2,329,677 | Determinants and Prognostic Implications of Hepatorenal Dysfunction in Adults With Congenital Heart Disease.<Pagination><StartPage>1742</StartPage><EndPage>1750</EndPage><MedlinePgn>1742-1750</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.cjca.2022.07.018</ELocationID><ELocationID EIdType="pi... | Aortic regurgitation (AR), also known as aortic insufficiency, is the reverse blood flow from the aorta into the left ventricle (LV) during diastole. AR can result from either valve leaflets or primary aortic root disease.<CopyrightInformation>Copyright © 2023, StatPearls Publishing LLC.</CopyrightInformation></Ab... |
2,329,678 | Preservation of frontal white matter tracts in ventricular surgery: favoring an anterior interhemispheric transcallosal approach vs a transcortical transfrontal transventricular approach. | Secondary to the creation of a surgical corridor and retraction, white matter tracts degenerate, causing long-term scarring with potential neurological consequences. Third and lateral ventricle tumors require surgery that may lead to cognitive impairment. Our objective is to compare the long-term consequences of a tran... |
2,329,679 | Left Ventricular Segmental Strain Identifies Unique Myocardial Deformation Patterns After Intrinsic and Extrinsic Stressors in Mice. | We used segmental strain analysis to evaluate whether intrinsic (diet-induced obesity [DIO]) and extrinsic (unpredictable chronic mild stress [UCMS]) stressors can alter deformational patterns of the left ventricle. Six-week-old male C57BL/6J mice were randomized into the lean or obese group (n = 24/group). M... |
2,329,680 | Biventricular biaxial mechanical testing and constitutive modelling of fetal porcine myocardium passive stiffness. | The evaluation of fetal heart mechanical function is becoming increasingly important for determining the prognosis and making subsequent decisions on the treatment and management of congenital heart diseases. Finite Element (FE) modelling can potentially provide detailed information on fetal hearts, and help perform vi... |
2,329,681 | A recurrent homozygous missense DPM3 variant leads to muscle and brain disease. | Biallelic pathogenic variants in the genes encoding the dolichol-phosphate mannose synthase subunits (DPM) which produce mannosyl donors for glycosylphosphatidylinositols, N-glycan and protein O- and C-mannosylation, are rare causes of congenital disorders of glycosylation. Pathogenic variants in DPM1 and DPM2 are asso... |
2,329,682 | Myocardial work: The analytical methodology and clinical utilities.<Pagination><StartPage>46</StartPage><EndPage>59</EndPage><MedlinePgn>46-59</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.hjc.2022.07.007</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S1109-9666(22)00114-2</ELocationID>... | The evaluation of left ventricular (LV) systolic function is an essential part of the clinical practice of cardiology. Although left ventricular ejection fraction (LVEF) is the most validated and widely used parameter, it has fundamental limitations. LV strain is more sensitive to detect subtle myocardial dysfunction w... |
2,329,683 | Pulmonary valve involvement and left ventricular thrombosis in Behçet's disease: a case report and literature review.<Pagination><StartPage>1607</StartPage><MedlinePgn>1607</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.55563/clinexprheumatol/nocnjd</ELocationID><AuthorList CompleteYN="Y"><Auth... | <b><i>Background:</i></b> Prediabetes is a novel risk factor recently associated with changes in the left ventricle. Our aim is to determine if prediabetes is associated with heart failure (HF) and structural heart disease. <b><i>Methods:</i></b> We conducted a cross-sectional study and performed screening echocardiogr... |
2,329,684 | Left ventricular assist devices: A historical perspective at the intersection of medicine and engineering.<Pagination><StartPage>2343</StartPage><EndPage>2360</EndPage><MedlinePgn>2343-2360</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/aor.14371</ELocationID><Abstract><AbstractText>Over the la... | Over the last half-century, left ventricular assist device (LVAD) technology has progressed from conceptual therapy for failed cardiopulmonary bypass weaning to an accepted destination therapy for advanced heart failure. The history of LVAD engineering is defined by an initial development phase, which demonstrated the ... |
2,329,685 | Joubert-Plus syndrome with an atretic cephalocele: a case report. | Joubert syndrome is a rare heterogeneous disease affecting the cerebellum. It usually presents with hypotonia, abnormal breathing pattern, with distinctive cerebellar and brain stem malformation called the molar tooth sign. It may present with different organ involvement or with other neurological alterations such as D... |
2,329,686 | Paternal De Novo Variant of <i>TAOK1</i> in a Fetus With Structural Brain Abnormalities. | A dilated lateral ventricle is a relatively common finding on prenatal ultrasound, and the causes are complex. We aimed to explore the etiology of a fetus with a dilated lateral ventricle. Trio whole-exome sequencing was performed to detect causative variants. A <i>de novo</i> variant of <i>TAOK1</i> (NM_020791.2: c.22... |
2,329,687 | Beasts and Gods: Hippocampal quarrels before memory. | The first description and naming of the hippocampus is usually credited to Arantius (c. 1530 - 1589), whose comparison of the swelling inside the temporal horn of the lateral ventricle to a seahorse (hippocampus) or silkworm (bombyx) was published in the 1587 edition of the Anatomicarum Observationum Liber. However, in... |
2,329,688 | Amitriptyline improves cognitive and neuronal function in a rat model that mimics dementia with lewy bodies. | Dementia with Lewy bodies (DLB), a highly prevalent neurodegenerative disorder, causes motor and cognitive deficits. The main pathophysiologies of DLB are glutamate excitotoxicity and accumulation of Lewy bodies comprising α-synuclein (α-syn) and β-amyloid (Aβ). Amitriptyline (AMI) promotes expr... |
2,329,689 | Structural Brain Network Reorganization Following Anterior Callosotomy for Colloid Cysts: Connectometry and Graph Analysis Results. | The plasticity of the neural circuits after injuries has been extensively investigated over the last decades. Transcallosal microsurgery for lesions affecting the third ventricle offers an interesting opportunity to investigate the whole-brain white matter reorganization occurring after a selective resection of the gen... |
2,329,690 | Prenatal Diagnosis of Otocephaly: A Rare Facial Anomaly. | Otocephaly is a rare malformation characterized by agnathia (absence of the mandible), melotia (medially displaced ear pinna), aglossia (absence of the tongue) and microstomia (small oral aperture). This results due to failure of migration of the neural crest cells and is a defect of the first branchial arch. It is inc... |
2,329,691 | Injuries in Underbody Blast Fatalities: Identification of Five Distinct Mechanisms of Head Injury. | Previous research has shown that injuries to the head and neck were prevalent in 73% of all mounted fatalities of underbody blast. The mechanisms that cause such injuries to the central nervous system (CNS) are not yet known. The aim of this study was to identify the head and spinal injuries in fatalities due to underb... |
2,329,692 | Effect of cilia-induced surface velocity on cerebrospinal fluid exchange in the lateral ventricles. | Ciliary motility disorders are known to cause hydrocephalus. The instantaneous velocity of cerebrospinal fluid (CSF) flow is dominated by artery pulsation, and it remains unclear why ciliary dysfunction results in hydrocephalus. In this study, we investigated the effects of cilia-induced surface velocity on CSF flow us... |
2,329,693 | An induced pluripotent stem cell line (YCMi006-A) generated from a patient with hypertrophic cardiomyopathy who carries the ACTA1 mutation p.Ile343Met.<Pagination><StartPage>102874</StartPage><MedlinePgn>102874</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.scr.2022.102874</ELocationID><ELoca... | Hypertrophic cardiomyopathy (HCM) is a common inherited cardiovascular disease and is characterized by hypertrophy of the left ventricle. We reprogrammed peripheral blood mononuclear cells (PBMCs) from a HCM patient into pluripotent stem cells (iPSC) (YCMi006-A) carrying a heterozygous c.1029C > G mutation... |
2,329,694 | Inhibition of Dyrk1A Attenuates LPS-Induced Neuroinflammation via the TLR4/NF-κB P65 Signaling Pathway. | Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) is a highly conserved protein kinase, playing a key role in the regulation of physiological brain functions and pathological processes. In Alzheimer's disease (AD), Dyrk1A promotes hyperphosphorylation of tau protein and abnormal aggregation of amyl... |
2,329,695 | Lumbar-peritoneal shunt for idiopathic normal pressure hydrocephalus and secondary normal pressure hydrocephalus. | Normal-pressure hydrocephalus is a clinical syndrome consisting of dilated cerebral ventricles with the clinical triad of gait disturbance, cognitive impairment and/or urinary dysfunction. Lumbar-peritoneal (LP) shunt could improve idiopathic normal pressure hydrocephalus (iNPH) while its effectiveness on secondary NPH... |
2,329,696 | Normal Echocardiographic Reference Values of the Right Ventricular to Left Ventricular Endsystolic Diameter Ratio and the Left Ventricular Endsystolic Eccentricity Index in Healthy Children and in Children With Pulmonary Hypertension. | An accurate assessment of the right and left ventricle and their interaction is important in pediatric pulmonary hypertension (PH). Our objective was to provide normal reference values for the right ventricular to left ventricular endsystolic (RV/LVes) ratio and the LV endsystolic eccentricity index (LVes EI) in health... |
2,329,697 | Improved Ca<sup>2+</sup> release synchrony following selective modification of I<sub>tof</sub> and phase 1 repolarization in normal and failing ventricular myocytes.<Pagination><StartPage>52</StartPage><EndPage>62</EndPage><MedlinePgn>52-62</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.yjmcc... | Loss of ventricular action potential (AP) early phase 1 repolarization may contribute to the impaired Ca<sup>2+</sup> release and increased risk of sudden cardiac death in heart failure. Therefore, restoring AP phase 1 by augmenting the fast transient outward K<sup>+</sup> current (I<sub>tof</sub>) might be beneficial,... |
2,329,698 | Late-onset obstructive hydrocephalus associated with occipital encephalocele with large skull defect successfully treated by endoscopic third ventriculostomy. | Hydrocephalus is one of the most common presentations of occipital encephaloceles and usually develops within the first year of life. This case report presents a rare case of late-onset obstructive hydrocephalus associated with occipital encephalocele with an extraordinarily large occipital skull defect.</AbstractText>... |
2,329,699 | Ependymal Cilia: Physiology and Role in Hydrocephalus.<Pagination><StartPage>927479</StartPage><MedlinePgn>927479</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">927479</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3389/fnmol.2022.927479</ELocationID><Abstract><AbstractText>Cerebrospinal fluid ... | Cerebrospinal fluid (CSF), a colorless liquid that generally circulates from the lateral ventricles to the third and fourth ventricles, provides essential nutrients for brain homeostasis and growth factors during development. As evidenced by an increasing corpus of research, CSF serves a range of important functions. W... |
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