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2,332,800 | Fractal cardiovascular dynamics and baroreflex sensitivity after stellate ganglion block. | It has been shown that stellate ganglion block can attenuate baroreflex sensitivity. Our primary purpose in this study was to determine whether fractal dynamics (dynamic change of self-similar fluctuation patterns) of not only heart rate but also systolic blood pressure variability are involved in attenuation of barore... |
2,332,801 | Cryo-Imaging of Fluorescently-Labeled Single Cells in a Mouse. | We developed a cryo-imaging system to provide single-cell detection of fluorescently labeled cells in mouse, with particular applicability to stem cells and metastatic cancer. The Case cryo-imaging system consists of a fluorescence microscope, robotic imaging positioner, customized cryostat, PC-based control system, an... |
2,332,802 | Biphasic myopathic phenotype of mouse DUX, an ORF within conserved FSHD-related repeats. | Facioscapulohumeral muscular dystrophy (FSHD) is caused by contractions of D4Z4 repeats at 4q35.2 thought to induce misregulation of nearby genes, one of which, DUX4, is actually localized within each repeat. A conserved ORF (mDUX), embedded within D4Z4-like repeats, encoding a double-homeodomain protein, was recently ... |
2,332,803 | Safety and effectiveness of coadministration of intrathecal sufentanil and morphine in hyperbaric bupivacaine-based spinal anesthesia for cesarean section. | Subarachnoid block is a widely used technique for cesarean section. Opioids adding to the local anesthetics can improve its quality. In this prospective, randomized, double blind, controlled trial, we compared the effects of coadministration of intrathecal sufentanil and morphine with intrathecal sufentanil and a singl... |
2,332,804 | [Efficacy of sugammadex in the reversal of neuromuscular blockade induced by rocuronium in long-duration surgery: under inhaled vs. intravenous anesthesia]. | Sugammadex reverses neuromuscular blockade induced by aminosteroid agents by encapsulating these agents. The objective of this study was to compare the efficacy and safety of sugammadex to reverse a rocuronium-induced neuromuscular blockade in long-duration surgery in association with inhaled or intravenous anesthesia.... |
2,332,805 | Irrigated radiofrequency-biophysics and application to surgical ablation. | Surgical ablation has become a routine procedure in many institutions and is a nearing standard of care for certain conditions. A variety of energy sources are available to the surgeon to induce cell death and create a line of conduction block. This article provides a brief review of the biophysics of irrigated radiofr... |
2,332,806 | Comparison of sub-Tenon's block with i.v. fentanyl for paediatric vitreoretinal surgery. | Vitreoretinal (VR) surgery is associated with moderate to severe pain and significant postoperative nausea and vomiting (PONV). The study aimed to assess the effectiveness of sub-Tenon's block for providing perioperative analgesia in children undergoing VR surgery.</AbstractText>In a randomized, observer-blinded trial,... |
2,332,807 | The effects of intrathecal levobupivacaine and bupivacaine in the elderly. | The objective of this study was to compare the block durations and haemodynamic effects associated with intrathecal levobupivacaine or bupivacaine in elderly patients undergoing transurethral prostate surgery. Eighty patients were prospectively randomised to receive plain 1.5 ml levobupivacaine 0.5% (group levobupivaca... |
2,332,808 | Is there an advantage in using low-dose intrathecal bupivacaine for cesarean section? | Spinal anesthesia for cesarean section is associated with a high incidence of maternal hypotension. The aim of this study was to assess the efficacy of low-dose bupivacaine with fentanyl to reduce the incidence of hypotension in spinal anesthesia for cesarean section.</AbstractText>Forty pregnant women undergoing elect... |
2,332,809 | Exercise-induced vasculitis associated with autoimmune disease. | Exercised-induced vasculitis (EIV) is an underreported and frequently misdiagnosed condition that occurs on the lower extremities shortly after exercise. Most reported cases have presented in healthy-appearing individuals, but some cases have been linked to other disease processes. A case report is presented of recurri... |
2,332,810 | Performance and subjective effects of diazepam and d-amphetamine in high and low sensation seekers. | Although sensation-seeking status is associated with age of initiation and amount of drug use among adolescents, and sensitivity to the behavioral and reinforcing effects of drugs among young adults, it is unclear whether sensation-seeking status among adolescents is predictive of sensitivity to the pharmacological eff... |
2,332,811 | Congenital heart block associated with Sjögren syndrome: case report. | Congenital heart block is a rare complication of pregnancy associated with Sjögren Syndrome that may result in the death of the foetus or infant, or the need for pacing in the newborn or at a later stage.</AbstractText>The case is presented of a 64-year-old patient with primary Sjögren Syndrome and a history ... |
2,332,812 | Diagnosing cardiac sarcoidosis clinically without tissue confirmation. | A 52-year-old woman is described in whom cardiac sarcoidosis was diagnosed clinically on the basis of high-grade heart block, recurring ventricular tachyarrhythmias, and acute cardiac decompensation. Confirmation of sarcoidosis was not determined until necropsy. When it causes cardiac dysfunction, sarcoidosis rarely ca... |
2,332,813 | Development of a human immunodeficiency virus type 1-based lentiviral vector that allows efficient transduction of both human and rhesus blood cells. | Human immunodeficiency virus type 1 (HIV-1) vectors transduce rhesus blood cells poorly due to a species-specific block by TRIM5alpha and APOBEC3G, which target HIV-1 capsid and viral infectivity factor (Vif), respectively. We sought to develop a lentiviral vector capable of transducing both human and rhesus blood cell... |
2,332,814 | Spontaneous intracranial hypotension syndrome: a novel speculative physiopathological hypothesis and a novel patch method in a series of 28 consecutive patients. | Spontaneous intracranial hypotension (SIH) is a potentially serious pathological syndrome consisting of specific symptoms and neuroradiological signs that can sometimes be used to assess the efficacy of the treatment. In this paper the authors report a series of 28 patients with this syndrome who were all treated with ... |
2,332,815 | Novel strategies for the prevention of dementia from Alzheimer's disease. | As the world's population continues to age, Alzheimer's disease presents a looming public health crisis that, left unchecked, threatens to overwhelm health care systems throughout the developed world. In order to significantly tackle the most catastrophic and devastating symptom of Alzheimer's disease (AD)--dementia--w... |
2,332,816 | Interleukin 7 receptor alpha as a potential therapeutic target in transplantation. | Drugs targeting memory lymphocytes may allow for a better control of rejection in transplantation, particularly in immunized patients. In this article the rationale of targeting interleukin 7 receptor alpha (IL-7Ralpha), a molecule expressed by both memory and naive T cells, is reviewed in the context of transplantatio... |
2,332,817 | Freezing reaction in panic disorder patients associated with anticipatory anxiety. | Anticipatory anxiety can be described as a conditioned response with a defensive posture of freezing and autonomic activation. The purpose of this study was to assess the postural control analysis and autonomic activation in panic disorder (PD) patients presented with visual stimuli.</AbstractText>PD patients (n=29) an... |
2,332,818 | Effect of scalp infiltration with Bupivacaine on early hemodynamic responses during craniotomy under general anesthesia. | The present study was conducted to evaluate the effect of scalp infiltration with Bupivacaine on hemodynamic responses during early stimulation in craniotomy under general anesthesia. Thirty six patients were prospectively randomized to receive Bupivacaine scalp infiltration (B group) or a saline control (S group) as a... |
2,332,819 | First episode psychosis and the trail to secondary care: help-seeking and health-system delays. | People experience delays in receiving effective treatment for many illnesses including psychosis. These delays have adverse consequences in heart disease and cancer, and their causes have been the subject of much research but only in recent years have pathways to care in psychosis received such attention. We sought to ... |
2,332,820 | Tbx2 misexpression impairs deployment of second heart field derived progenitor cells to the arterial pole of the embryonic heart. | Tbx2 is a member of the T-box family of transcription factors that play important roles during heart development. In the embryonic heart tube, Tbx2 is expressed in non-chamber myocardium (outflow tract and interventricular canal) and has been shown to block chamber formation. We have developed a genetic system to condi... |
2,332,821 | Cutaneous absorption of Oleander: Fact or fiction. | Cardiac conduction disorders following oral ingestion of Oleander plant materials were documented earlier. Transcutaneous absorption of yellow oleander (Thevetia peruviana) leaf extract applied over non intact skin (raw wound) resulting in reversible cardiac conduction disorder observed in four healthy males who were f... |
2,332,822 | Strategic, political, and cultural aspects of IT implementation: improving the efficacy of an IT system in a large hospital.<Pagination><StartPage>191</StartPage><EndPage>207</EndPage><MedlinePgn>191-206; discussion 206-7</MedlinePgn></Pagination><Abstract><AbstractText>Healthcare spending will exceed $4 trillion by 20... | Healthcare spending will exceed $4 trillion by 2017, a trend that is leading executives to implement information technology (IT) systems to contain these rising costs. Studies show that numerous factors determine the outcome and net benefits of IT in healthcare. However, what happens when a newly implemented IT system ... |
2,332,823 | Traffic particles and occurrence of acute myocardial infarction: a case-control analysis. | We modelled exposure to traffic particles using a latent variable approach and investigated whether long-term exposure to traffic particles is associated with an increase in the occurrence of acute myocardial infarction (AMI) using data from a population-based coronary disease registry.</AbstractText>Cases of individua... |
2,332,824 | Continuous spinal anesthesia. | Continuous spinal anesthesia (CSA) is an underutilized technique in modern anesthesia practice. Compared with other techniques of neuraxial anesthesia, CSA allows incremental dosing of an intrathecal local anesthetic for an indefinite duration, whereas traditional single-shot spinal anesthesia usually involves larger d... |
2,332,825 | Clinical conditions associated with environmental exposures: an epidemiologic study in two communities in Juana Díaz, Puerto Rico. | A population-based cross-sectional design was used to compare the prevalence of respiratory and general symptoms and of respiratory and heart diseases in two communities of Juana Díaz, Puerto Rico: Guayabal, exposed to particulate matter from quarries and diesel exhaust; and Río Cañas Abajo, which has no... |
2,332,826 | Removal of out-of-plane fluorescence for single cell visualization and quantification in cryo-imaging. | We developed a cryo-imaging system, which alternates between sectioning (10-40 microm) and imaging bright field and fluorescence block-face image volumes with micron-scale-resolution. For applications requiring single-cell detection of fluorescently labeled cells anywhere in a mouse, we are developing software for redu... |
2,332,827 | Mitochondrial permeability transition pore opening as a promising therapeutic target in cardiac diseases. | In addition to their central role in ATP synthesis, mitochondria play a critical role in cell death. Oxidative stress accompanied by calcium overload, ATP depletion, and elevated phosphate levels induces mitochondrial permeability transition (MPT) with formation of nonspecific MPT pores (MPTP) in the inner mitochondria... |
2,332,828 | [Epidural analgesia in latent phase of labor: effects on length of labor and mode of delivery]. | To compare the outcome of ropivacaine plus sufentanil for patient-controlled epidural analgesia between nulliparous women presenting in latent and active labor.</AbstractText>360 nulliparous parturients were randomized according to cervix dilation. Latent group (cervix dilation < 3 cm) received 0.1% ropivacaine with... |
2,332,829 | The relationships of impulsivity and cardiovascular responses: the role of gender and task type. | The present study was conducted to assess the relationships of impulsivity with both baseline cardiovascular levels and reactivity during two laboratory stressors in both female and male young adults. Heart rate (HR), blood pressure (BP), and heart rate variability (HRV) were measured at rest and during a reaction time... |
2,332,830 | Reversed drift in heart rate but increased oxygen uptake at fixed work rate during 24 h ultra-endurance exercise. | In this paper we report a reversed drift in heart rate (HR) but increased oxygen uptake (VO(2)) during ultra-endurance exercise. Nine well-trained male athletes performed 24-h exercise in a controlled laboratory setting, with alternating blocks of kayaking, running and cycling. Each block included 110 min of exercise a... |
2,332,831 | Adverse effects of combined spinal-epidural versus traditional epidural analgesia during labor. | To compare two neuraxial block techniques during labor for maternal and fetal effects.</AbstractText>Women in labor at term with cephalic singleton fetuses were randomized (nonblinded) to receive either labor epidural (EPI) or combined spinal-epidural (CSE) analgesia. Primary outcome was prolonged deceleration (PD) of ... |
2,332,832 | Post-ischemic infusion of atrial natriuretic peptide attenuates warm ischemia-reperfusion injury in rat lung. | The serious shortage of organs for transplantation, especially lungs, has drawn increasing attention to donation after cardiac death and protection of organs against warm ischemic injury. Atrial natriuretic peptide (ANP) activates guanylate cyclase receptors and increases cyclic guanosine monophosphate (cGMP) levels, w... |
2,332,833 | A comparison of the efficacy and cardiorespiratory effects of four medetomidine-based anaesthetic protocols in the red fox (Vulpes vulpes). | To evaluate the anaesthetic and cardiorespiratory effects of four anaesthetic protocols in red foxes (Vulpes vulpes).</AbstractText>Prospective, blinded and randomized complete block design.</AbstractText>Ten adult captive red foxes.</AbstractText>Foxes were anaesthetized by intramuscular (IM) injection using four prot... |
2,332,834 | [Continuous epidural anaesthesia vs paravertebral block for lung surgery--a comparative study]. | This prospective randomized study compared the effects of two techniques--thoracic epidural analgesia (TEA), and thoracic paravertebral analgesia (TPVA), on pain control and haemodynamics after thoracotomy.</AbstractText>Sixty adult ASA 1 and 2 patients were randomly assigned to two equal groups to receive either: (I) ... |
2,332,835 | Mobile Block Hessian Approach with Adjoined Blocks: An Efficient Approach for the Calculation of Frequencies in Macromolecules. | In an earlier work, the authors developed a new method, the mobile block Hessian (MBH) approach, to accurately calculate vibrational modes for partially optimized molecular structures [ J. Chem. Phys. 2007 , 126 ( 22 ), 224102. ]. It is based on the introduction of blocks, consisting of groups of atoms, that can move a... |
2,332,836 | Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer. | Recent studies have demonstrated the importance of coagulation factor X (FX) in adenovirus (Ad) serotype 5-mediated liver transduction in vivo. FX binds to the adenovirus hexon hypervariable regions (HVRs). Here, we perform a systematic analysis of FX binding to Ad5 HVRs 5 and 7, identifying domains and amino acids cri... |
2,332,837 | Effect of i.v. phenylephrine or ephedrine on the ED50 of intrathecal bupivacaine with fentanyl for caesarean section. | Prophylactic infusion of phenylephrine to prevent hypotension at Caesarean section has been shown to decrease the rostral spread of intrathecal plain levobupivacaine and intrathecal hyperbaric bupivacaine by a median of two dermatomes compared with ephedrine. The aim of this study was to determine the median effective ... |
2,332,838 | Loss of cerebrovascular Shaker-type K(+) channels: a shared vasodilator defect of genetic and renal hypertensive rats. | The cerebral arteries of hypertensive rats are depolarized and highly myogenic, suggesting a loss of K(+) channels in the vascular smooth muscle cells (VSMCs). The present study evaluated whether the dilator function of the prominent Shaker-type voltage-gated K(+) (K(V)1) channels is attenuated in middle cerebral arter... |
2,332,839 | Air pollution exposure and self-reported cardiovascular disease. | Studies suggest that increases of fine particle concentrations (PM2.5) could be linked with a rise in cardiovascular disease. With approximately 25% of American adults aged 30 and older reporting having either heart disease or hypertension it is possible that exposure to air pollution could have significant public heal... |
2,332,840 | Adverse drug reactions to local anaesthetics: a review of the French pharmacovigilance database. | Some evidence of significant patient morbidity or mortality has been reported with the use of local anaesthetics (LAs). The most common adverse drug reactions (ADRs) to LAs are neurological (seizures) and cardiac (conduction disorders, cardiac arrests). However, little is known about other adverse drug reactions (ADRs)... |
2,332,841 | Lixivaptan: a novel vasopressin receptor antagonist. | Arginine vasopressin, also known as antidiuretic hormone, is a neuropeptide that functions in the maintenance of body water homeostasis. Inappropriate secretion of vasopressin has been implicated in the pathophysiology of multiple diseases, including polycystic kidney disease, syndrome of inappropriate antidiuretic hor... |
2,332,842 | Preoperative intravenous clonidine in the surgical treatment of cataract: evaluation of the clinical benefits. | Clonidine has been used in anesthesia for its sedative and analgesic properties, and to achieve greater hemodynamic stability with reduction in intra-ocular pressure. This study evaluated the clinical effects of intravenous clonidine (2.5 microg.kg(-1)) on the intra-ocular pressure (IOP), hemodynamic parameters, and po... |
2,332,843 | A lateral percutaneous technique for stellate ganglion blockade in rats. | In the present study, we describe and show the efficacy of a lateral approach to stellate ganglion block (SGB) in rats.</AbstractText>Twenty-one rats were randomized into three groups: the posterior technique group (n = 7), the lateral technique group (n = 7), and the control group (n = 7). Thiopental was administered ... |
2,332,844 | [Grand mal convulsion after an interscalene block with ropivacaine]. | We report a case of grand mal convulsion due to inadvertent intravascular injection of ropivacaine. An 83-year-old woman was scheduled for upper limb surgery. The interscalene block was performed with neurostimulator and 0.5% ropivacaine 30 ml was injected after careful negative aspiration. Approximately 3 min after th... |
2,332,845 | Pharmacological profile of the inhibition by dihydroergotamine and methysergide on the cardioaccelerator sympathetic outflow in pithed rats. | The present study set out to analyse the pharmacological profile of the inhibitory responses induced by the antimigraine agents dihydroergotamine (DHE) and methysergide on the tachycardic responses to preganglionic sympathetic stimulation in pithed rats. For this purpose, 132 male Wistar normotensive rats were pithed a... |
2,332,846 | Images in cardiovascular medicine. Cannon a wave.<Pagination><StartPage>e381</StartPage><EndPage>e383</EndPage><MedlinePgn>e381-3</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1161/CIRCULATIONAHA.108.833095</ELocationID><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Chen</LastName><ForeNa... | Aortic stenosis and aortic insufficiency in young children present multiple challenges to the patient, family, and surgeon. Mechanical valves require anticoagulation therapy, which is a poor option in active youngsters and noncompliant adolescents. Aortic valvuloplasty and the various forms of the Ross/Ross-Konno opera... |
2,332,847 | A histomorphometric study on collagen-apatite composite as a graft material: the influence of gap size at the titanium-bone interface in animal model. | The purpose of this study was to evaluate the healing process of collagen-apatite composite (CAC) at the titanium-bone interface in animal model. Small gaps (0.5 or 1.0 mm-sized wells) were prepared in the epoxy-resin block implants coated with pure titanium. The gaps were filled with CAC or demineralized freeze-dried ... |
2,332,848 | Development of bronchus-associated lymphoid tissue hyperplasia following lipopolysaccharide-induced lung inflammation in rats. | Gram-negative bacterial endotoxin lipopolysaccharide (LPS) administration has been used as an animal model of sepsis-related acute lung injury and adult respiratory distress syndrome (ALI/ARDS). This paper describes the lung histology following lung injury induced by the intraperitoneal (i.p.) administration of endotox... |
2,332,849 | Optimal dose of sufentanil in children for intubation after sevoflurane induction without neuromuscular block. | We studied 63 ASA I children (age 2-8 yr) to determine the sufentanil dose needed to facilitate intubation under excellent conditions after inhalation induction with various end-tidal concentrations of sevoflurane without neuromuscular block.</AbstractText>Subjects were allocated randomly to receive sevoflurane end-tid... |
2,332,850 | 'Muscle-sparing' statins: preclinical profiles and future clinical use. | Coronary heart disease (CHD) is a leading cause of death in the US, and hypercholesterolemia is a key risk factor for this disease. The current standard of care for treating hypercholesterolemia is the use of HMG-CoA reductase inhibitors, also known as statins, which block the rate-limiting step of cholesterol biosynth... |
2,332,851 | Transient loss of consciousness 1: causes and impact of misdiagnosis. | Part 1 of this two-part unit outlines the various possible causes of transient loss of consciousness (blackouts), the importance of accurate diagnosis and the impact of misdiagnosis. It also discusses the establishment of specialist clinics in order to help with diagnosis and management. |
2,332,852 | Critical analysis of autoregressive and fast Fourier transform markers of cardiovascular variability in rats and humans. | The autonomic nervous system plays an important role in physiological and pathological conditions, and has been extensively evaluated by parametric and non-parametric spectral analysis. To compare the results obtained with fast Fourier transform (FFT) and the autoregressive (AR) method, we performed a comprehensive com... |
2,332,853 | Comparison of fentanyl and sufentanil as adjuncts to bupivacaine for labor epidural analgesia. | To compare the clinical efficacy of theoretically equipotent doses of fentanyl and sufentanil, each in combination with bupivacaine, for patient-controlled epidural analgesia (PCEA) for labor.</AbstractText>Single-blinded, randomized study.</AbstractText>University hospital.</AbstractText>48 ASA physical status I and I... |
2,332,854 | [Study on the use of a smart pillbox to improve treatment compliance]. | To assess the usefulness of the Practidose individualised dispensing and dosing pillbox system in improving treatment compliance (TC).</AbstractText>Open-labelled, randomised, clinical trial.</AbstractText>Cordoba province from April to September 2005.</AbstractText>A total of 220 patients 70 years diagnosed with ineff... |
2,332,855 | Music may reduce anxiety during invasive procedures in adolescents and adults. | A block randomised controlled trial was conducted.</AbstractText>Patients in the music (test) group listened to selected sedative music using headphones throughout the root canal treatment procedure. The control group subjects wore headphones but without the music.</AbstractText>Anxiety was measured before the study an... |
2,332,856 | The Paracetamol (Acetaminophen) In Stroke (PAIS) trial: a multicentre, randomised, placebo-controlled, phase III trial. | High body temperature in the first 12-24 h after stroke onset is associated with poor functional outcome. The Paracetamol (Acetaminophen) In Stroke (PAIS) trial aimed to assess whether early treatment with paracetamol improves functional outcome in patients with acute stroke by reducing body temperature and preventing ... |
2,332,857 | The endothelial glycocalyx mediates shear-induced changes in hydraulic conductivity. | Recent in vitro and in vivo studies have reported fluid shear stress-induced increases in endothelial layer hydraulic conductivity (L(p)) that are mediated by an increased production of nitric oxide (NO). Other recent studies have shown that NO induction by shear stress is mediated by the glycocalyx that decorates the ... |
2,332,858 | Casein haplotypes and their association with milk production traits in Norwegian Red cattle. | A high resolution SNP map was constructed for the bovine casein region to identify haplotype structures and study associations with milk traits in Norwegian Red cattle. Our analyses suggest separation of the casein cluster into two haplotype blocks, one consisting of the CSN1S1, CSN2 and CSN1S2 genes and another one co... |
2,332,859 | Hypotension after spinal anesthesia for cesarean section: identification of risk factors using an anesthesia information management system. | To determine risk factors for developing hypotension after spinal anesthesia for cesarean section to prevent obstetric patients from hypotensive episodes potentially resulting in intrauterine malperfusion and endangering the child.</AbstractText>The data from 503 women, having received spinal anesthesia for cesarean se... |
2,332,860 | The analgesic effects of ropivacaine in ilioinguinal-iliohypogastric nerve block in children--concentration or volume? | The aim of the present study was to compare the analgesic effects of ripovacaine when used as high concentration/small volume, versus its use as high volume/low concentration, in ilioinguinal-iliohypogastric nerve block in children.</AbstractText>This is a prospective single-blind randomized study consisting of 72 chil... |
2,332,861 | The effect of scalp block and local infiltration on the haemodynamic and stress response to skull-pin placement for craniotomy. | The insertion of skull pins into the periosteum induces not only a haemodynamic response but also an increase in stress hormones. We compared the effects of scalp-nerve block, infiltration anaesthesia, and routine anaesthesia during skull-pin insertion on haemodynamic and stress responses to craniotomy.</AbstractText>F... |
2,332,862 | A comparison of retrobulbar block, sub-Tenon block, and topical anesthesia during cataract surgery. | This randomized, double-blinded, prospective study was performed to compare the intraoperative hemodynamic variables and the patient-reported outcomes, such as intra- and postoperative analgesia and patient satisfaction, of retrobulbar block, sub-Tenon block, and topical anesthesia during cataract surgery under monitor... |
2,332,863 | Spinal anesthesia with 3.75 mg of 0.25% hyperbaric bupivacaine for diabetic foot surgery. | Spinal anesthesia in the sitting position with low-dose local anesthetics usually provides satisfactory anesthesia for diabetic foot surgery because most operations do not require tourniquet application. This study was designed to investigate the influence of different sitting periods after subarachnoid injection of lo... |
2,332,864 | 'Reverberation time', dreaming and the capacity to dream. | In this paper the author suggests that understanding the roots of the subjective sense of time can throw light on the disturbances in psychic time which are found in particular in the more severe pathologies. She introduces the argument that the roots of the development of the sense of time rest on a primitive sense of... |
2,332,865 | Treatment of persistent sinus bradycardia with intermittent symptoms: are guidelines clear? | There is uncertainty in the aetiology of syncope in subjects with persistent sinus bradycardia (SB) (sick sinus syndrome). The results of pathophysiological studies suggest a reflex origin of syncope in the vast majority of subjects with SB. From a nosological point of view, 'syndrome' is defined as the association of ... |
2,332,866 | Urocortin induces interleukin-6 release from rat cardiomyocytes through p38 MAP kinase, ERK and NF-kappaB activation. | CRH and its structurally related peptide urocortin (Ucn) are released under stress. Ucn is a potent agonist for CRH-receptor 2 (CRH-R2), which is strongly expressed in rodent heart. Stress induces Ucn mRNA expression in the heart, where it may be cardioprotective. However, increasing evidence indicates that Ucn may als... |
2,332,867 | Antibody reactivity to alpha-enolase in mothers of children with congenital heart block. | To evaluate the frequency of anti-alpha-enolase antibodies in the sera of mothers whose children have congenital heart block (CHB), given provocative results in which alpha-enolase, a membrane protein, was recognized by monoclonal antibodies reactive with the peptide p200 of 52 kDa Ro/SSA in a neonatal rat heart librar... |
2,332,868 | Is it Williams syndrome? GTF2IRD1 implicated in visual-spatial construction and GTF2I in sociability revealed by high resolution arrays. | Genetic contributions to human cognition and behavior are clear but difficult to define. Williams syndrome (WS) provides a unique model for relating single genes to visual-spatial cognition and social behavior. We defined a approximately 1.5 Mb region of approximately 25 genes deleted in >98% of typical WS and then ... |
2,332,869 | Comparison of glutathione peroxidase 1 and iodothyronine deiodinase 1 mRNA expression in murine liver after feeding selenite or selenized yeast. | The experiment was conducted to compare the effect of different selenium sources on the expression of glutathione peroxidase 1 (GPx1) and iodothyronine deiodinase 1 (Dio1) mRNA in mice by quantitative real-time PCR. A total of 60 male Kunming mice at average body weight of 20 g were allotted to three groups in a random... |
2,332,870 | A reengineered hospital discharge program to decrease rehospitalization: a randomized trial. | Emergency department visits and rehospitalization are common after hospital discharge.</AbstractText>To test the effects of an intervention designed to minimize hospital utilization after discharge.</AbstractText>Randomized trial using block randomization of 6 and 8. Randomly arranged index cards were placed in opaque ... |
2,332,871 | ETA receptor blockade with atrasentan prevents hypertension with the multitargeted tyrosine kinase inhibitor ABT-869 in telemetry-instrumented rats. | ABT-869 is a novel multitargeted inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptor tyrosine kinases (RTKs) with potent antiangiogenic properties that slow tumor progression. Vascular endothelial growth factor receptor blockade has been shown to produce hypertension. Atrasentan ... |
2,332,872 | Unilateral phrenic nerve block guided by ultrasonography and nerve stimulator for the treatment of hiccup developed after tongue cancer operation: A case report. | Hiccups are common benign and usually transient phenomenon that occur in nearly everyone. However, persistent or intractable hiccups can cause multiple problems including malnutrition, weight loss, fatigue, dehydration, insomnia, and wound dehiscence. We have experienced a case of postoperative persistent hiccup. The p... |
2,332,873 | China makes an impressive breakthrough in avian influenza virus research - Discovering the "heart" of avian infl uenza virus. | The successive appearance of strains of epizootic avian influenza A virus with the subtype H5N1 in China has attracted considerable concern from the public and Chinese authorities. According to the latest WHO estimates as of February 2, 2009, the number of H5N1 virus deaths in China totaled 25, second only to Indonesia... |
2,332,874 | Blind identification of evoked human brain activity with independent component analysis of optical data. | Diffuse optical tomography (DOT) methods observe hemodynamics in the brain by measuring light transmission through the scalp, skull, and brain. Thus, separating signals due to heart pulsations, breathing movements, and systemic blood flow fluctuations from the desired brain functional responses is critical to the fidel... |
2,332,875 | The successful use of peripheral nerve blocks for femoral amputation. | We present a case report of four patients with severe cardiac insufficiency where peripheral nerve blocks guided by either nerve stimulation or ultrasonography were the sole anaesthetic for above-knee amputation. The patients were breathing spontaneously and remained haemodynamically stable during surgery. Thus, use of... |
2,332,876 | The impact of meloxicam on postsurgical stress associated with cautery dehorning. | The objectives were to determine the duration of the stress response associated with cautery dehorning and to assess the effectiveness of the nonsteroidal anti-inflammatory drug meloxicam (Metacam, 20 mg/mL solution for injection) for reducing that response. Sixty Holstein heifer calves were blocked by age and randomly... |
2,332,877 | FPGA-core defibrillator using wavelet-fuzzy ECG arrhythmia classification. | An electrocardiogram (ECG) feature extraction and classification system has been developed and evaluated using Quartus II 7.1 belong to Altera Ltd. In wavelet domain QRS complexes were detected and each complex was used to locate the peaks of the individual waves. Then, fuzzy classifier block used these features to cla... |
2,332,878 | Block circulant quasi-band matrix property for the SENSE unfolding in k-space and justification for GRAPPA. | The k-space unfolding matrix for parallel imaging in MRI was examined and was found to have the structure of block circulant quasi-band, providing a rigorous mathematical justification for the interpolation kernel in the commonly used GRAPPA method. The optimal GRAPPA kernel size and dimension were closely related to s... |
2,332,879 | Comparison of analysis techniques of diabetic cardiac action potential propagation. | Diabetes is known to cause a variety of cardiovascular complications. One of the effects of the diabetic state is that the conduction velocity of the action potential front may be delayed in the myocardium. Current methods of measuring this effect have included optical mapping methods, from which the time required for ... |
2,332,880 | An attempt to prevent senescence: a mitochondrial approach. | Antioxidants specifically addressed to mitochondria have been studied to determine if they can decelerate senescence of organisms. For this purpose, a project has been established with participation of several research groups from Russia and some other countries. This paper summarizes the first results of the project. ... |
2,332,881 | Comparison of the effect of sevoflurane and halothane anesthesia on the fall in heart rate as a predictor of successful single shot caudal epidural in children. | To investigate the effect of sevoflurane anesthesia on heart rate HR fall with the injection of the initial drug in caudal space to confirm the correct needle placement.</AbstractText>After the ethical approval was obtained from the hospital's ethics committee, a prospective, randomized, clinical study was designed in ... |
2,332,882 | A method for the analysis of domain movements in large biomolecular complexes. | A new method for the analysis of domain movements in large, multichain, biomolecular complexes is presented. The method is applicable to any molecule for which two atomic structures are available that represent a conformational change indicating a possible domain movement. The method is blind to atomic bonding and atom... |
2,332,883 | Effects of iron oxide nanoparticles on cardiac differentiation of embryonic stem cells. | The therapeutic potential of transplantation of embryonic stem cells (ESCs) in animal model of myocardial infarction has been consistently demonstrated. The development of superparamagnetic iron oxide (SPIO) nanoparticles labeling and cardiac magnetic resonance imaging (MRI) have been increasingly used to track the mig... |
2,332,884 | Differential protein expression in heart in UT-B null mice with cardiac conduction defects. | Cardiac conduction defects were found in transgenic mice deficient in urea transporter UT-B. To investigate the molecular mechanisms of the conduction defects caused by UT-B deletion, we studied the protein expression profiles of heart tissue (comprising most conduction system) in wild-type versus UT-B null mice at dif... |
2,332,885 | The cardioprotective effect of postconditioning is mediated by ARC through inhibiting mitochondrial apoptotic pathway. | Postconditioning protects the heart against ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis. However, the molecular mechanism by which postconditioning suppresses apoptosis remains to be fully understood. Apoptosis repressor with caspase recruitment domain (ARC) has been demonstrated to possess the ab... |
2,332,886 | A case of an acquired high-degree AV block in a pregnant woman. | Acquired heart block during pregnancy is rare. We describe the case of a 29-year-old pregnant female with fatigue due to an unexplained high-degree AV conduction disorder. She was treated with a dual chamber pacing system. Further pregnancy and delivery were without complications. The sparse literature on this topic is... |
2,332,887 | [The lived experience of struggling against illness for patients with amyotrophic lateral sclerosis]. | The purpose of this study was to identify and describe phenomenological structures of the lived experience of struggling against an illness for patients with Amyotrophic Lateral Sclerosis (ALS).</AbstractText>The participants were 7 patients with ALS recruited by snowball sampling who agreed to participate in this rese... |
2,332,888 | Activation of cytosolic phospholipase A2-{alpha} as a novel mechanism regulating endothelial cell cycle progression and angiogenesis. | Release of endothelial cells from contact-inhibition and cell cycle re-entry is required for the induction of new blood vessel formation by angiogenesis. Using a combination of chemical inhibition, loss of function, and gain of function approaches, we demonstrate that endothelial cell cycle re-entry, S phase progressio... |
2,332,889 | Postoperative patient-controlled thoracic epidural analgesia: importance of dose compared to volume or concentration. | This randomised and blinded study evaluated the quality of analgesia and the incidence of side-effects of two concentrations of levobupivacaine (0.15% and 0.5%) given as an equal mg-bolus-dose (5 mg) via patient-controlled epidural analgesia after lower abdominal surgery. The patients were randomly assigned into two gr... |
2,332,890 | Implantation of lumenless pacing leads at the inter-atrial septum and right ventricular outflow tract with deflectable catheter-sheath. | Current permanent right ventricular and right atrial endocardial pacing leads are implanted utilizing a central lumen stylet. Right ventricular apex pacing initiates an abnormal asynchronous electrical activation pattern, which results in asynchronous ventricular contraction and relaxation. When pacing from right atria... |
2,332,891 | Physiologic and cardiac roles of beta-arrestins.<Pagination><StartPage>300</StartPage><EndPage>308</EndPage><MedlinePgn>300-8</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.yjmcc.2008.11.015</ELocationID><Abstract><AbstractText>Beta-arrestin1 and beta-arrestin2 were initially identified by se... | Beta-arrestin1 and beta-arrestin2 were initially identified by sequence homology to visual arrestins and by their ability to bind to and inactivate signaling of the beta-2-adrenergic receptor in a process known as desensitization. While the role of beta-arrestins in desensitization has been known for some time, more re... |
2,332,892 | Vitamin C in plasma is inversely related to blood pressure and change in blood pressure during the previous year in young Black and White women. | The prevalence of hypertension and its contribution to cardiovascular disease risk makes it imperative to identify factors that may help prevent this disorder. Extensive biological and biochemical data suggest that plasma ascorbic acid may be such a factor. In this study we examined the association between plasma ascor... |
2,332,893 | The optimum concentration of levobupivacaine for intra-operative caudal analgesia in children undergoing inguinal hernia repair at equal volumes of injectate. | Probit analysis was used to predict the median effective concentration (EC(50)) and the 95% effective concentration (EC(95)) values of levobupivacaine for caudal analgesia in children at equal volumes of injectate. Sixty children scheduled for inguinal herniorrhaphy were recruited. Anaesthesia was induced with sevofura... |
2,332,894 | Calcium and vitamin D intakes may be positively associated with brain lesions in depressed and nondepressed elders. | Studies indicate that diet and vascular calcification may be related to the occurrence of brain lesions, although the importance of dietary calcium and vitamin D has not been investigated. The objective of this study was to test the hypothesis that calcium and vitamin D intakes would be positively associated with brain... |
2,332,895 | [Comparison of lumbar plexus block and epidural block for elderly patients undergoing intertrochanteric femoral fracture surgery]. | To compare the anesthesia efficacy, hemodynamics, recovery of passage of gas by anus and bladder function in elderly patients with operation of intertrochanteric femoral fracture with epidural or lumbar plexus block.</AbstractText>Sixty patients with intertrochanteric femoral fracture, aged 65-97, were randomly divided... |
2,332,896 | Effect of some acute and prophylactic antimigraine drugs on the vasodepressor sensory CGRPergic outflow in pithed rats. | This study analyzed in pithed rats the effect of several acute and prophylactic antimigraine drugs on the CGRPergic vasodepressor sensory outflow, in an attempt to investigate systemic cardiovascular effects in a model unrelated to migraine.</AbstractText>Male Wistar pithed rats were pretreated with continuous i.v. inf... |
2,332,897 | Thoracic epidural analgesia with low concentration of bupivacaine induces thoracic and lumbar sympathetic block: a randomized, double-blind clinical trial. | Clinical benefits of thoracic epidural anesthesia (TEA) are partly ascribed to thoracic sympathetic block. However, data regarding sympathetic activity during TEA are scarce and contradictory. This prospective, randomized, double-blind study evaluated the segmental propagation of sympathetic block after low-concentrati... |
2,332,898 | Cardioprotection by postconditioning is lost in WOKW rats with metabolic syndrome: role of glycogen synthase kinase 3beta. | Postconditioning by repetitive I/R cycles immediately after onset of reperfusion protects the heart. Metabolic disorders undermine the protection of preconditioning. The present study tested whether postconditioning protects hearts from rats with established metabolic syndrome [Wistar-Ottawa-Karlsburg W rats (WOKW)].</... |
2,332,899 | [Complete heart block and myocardial ischaemia during a severe anaphylactic reaction]. | An 83-year-old man had to be operated under general anaesthesia for a head skin tumor. The preanaesthetic exam of the cardiovascular function was reassuring but a cardiac arrest with a complete heart block occurred a few minutes after induction of anaesthesia. Resuscitation managing was successful but a myocardial isch... |
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