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28,800
Deep venous thrombosis in patients with acute pulmonary embolism: prevalence, risk factors, and clinical significance.
To determine the prevalence of lower-limb deep venous thrombosis (DVT) that can be detected by compression ultrasonography (CUS) in patients with symptomatic pulmonary embolism (PE) diagnosed with spiral CT pulmonary angiography (CTPA); and to explore the risk factors for positive CUS results and the prognostic signifi...
28,801
Quantitative gene expression in Budd-Chiari syndrome: a molecular approach to the pathogenesis of the disease.
Budd-Chiari syndrome (BCS) is associated with parenchymal changes leading to major architecture remodelling. In order to gain further insight into the pathogenesis of BCS, we investigated expression of a set of genes involved in the course of chronic liver diseases.</AbstractText>Quantitative expression of 35 selected ...
28,802
Study of portal vein thrombosis in patients with idiopathic portal hypertension in Japan.
<AbstractText Label="BACKGROUND/AIMS" NlmCategory="OBJECTIVE">The aim of this study was to elucidate the incidence and clinical manifestations of portal vein thrombosis (PVT) in patients with idiopathic portal hypertension (IPH) in Japan during long-term follow-up.</AbstractText>Twenty-two patients with IPH were examin...
28,803
[Coagulation parameters associated with inhaled glucocorticosteroid therapy in stable asthma].
The aim of this study was to determine if there are changes in laboratory investigations which allow to recognize coagulation disturbances associated with inhaled glucocorticoid therapy.</AbstractText>The study group consist of 26 patients with stable asthma (5 male, 21 female) without risk factors of venous thrombosis...
28,804
[Liver abscesses with portal and mesenteric vein thrombosis in combination with late onset of appendicitis].
Pyogenic liver abscesses are caused by appendicitis in less than 10%. Also the ascending septic inflammation of portal vein (pylephlebitis) could be a serious complication of intra-abdominal infection. Although pylephlebitis is not frequent today, its' mortality and morbidity rates remain high. We describe a case of yo...
28,805
[Prophylaxis of venous thromboembolic disease in patients after the proximal femoral surgery].
Patients undergoing elective hip replacement and surgery for hip fracture are at increased risk of venous thromboembolic disease, a potentially preventable cause of mortality and morbidity. Although the association between these operations and venous thromboembolism has been recognized many years ago, there is still gr...
28,806
An evaluation of the impact of the ventilator care bundle.
A number of interventions have been shown to improve the outcomes of patients who are invasively ventilated in intensive care units (ICUs). However, significant problems still exist in implementing research findings into clinical practice. The aim of this study was to assess whether the systematic and methodical implem...
28,807
Lemierre syndrome.
Lemierre syndrome is characterized by pharyngitis followed by Fusobacterium necrobacillosis sepsis complicated by internal jugular vein thrombosis and infectious metastatic abscesses. It has been considered to be a rare disease until the last decade when a larger number of cases have been reported. We discuss a case of...
28,808
Pivotal role of PAI-1 in a murine model of hepatic vein thrombosis.
Hepatic veno-occlusive disease (VOD) is a common complication of high-dose chemotherapy associated with bone marrow transplantation. While the pathogenesis of VOD is uncertain, plasminogen activator inhibitor-1 (PAI-1) has emerged as a diagnostic marker and predictor of VOD in humans. In this study, we investigated the...
28,809
Contraceptive-related cerebral venous thrombosis with profuse vaginal bleed.
Women on hormonal therapy for menorrhagia are at risk for cerebral venous thrombosis.</AbstractText>This scenario may become complicated when there is profuse vaginal bleed with the withdrawal of hormonal therapy. There are no reports describing the possible therapeutic approaches in this clinical situation.</AbstractT...
28,810
Central venous catheter thrombosis complicated by paradoxical embolism in a patient with diabetic ketoacidosis and respiratory failure.
Paradoxical embolus should be suspected in young patients with cerebrovascular events who do not have any vascular risk factors. There is significant controversy as to how best to treat his phenomenon.</AbstractText>A case observation in a tertiary care center.</AbstractText>A 46-year-old was admitted to the intensive ...
28,811
The MTHFR 677TT and 677CT/1298AC genotypes in Cypriot patients may be predisposing to hypertensive nephrosclerosis and chronic renal failure.
The homozygous 677TT mutation of the MTHFR gene has been linked to deep vein thrombosis and to arterial atherosclerotic events of the coronary, carotid and peripheral arteries. Its putative association with renal arteriosclerosis and chronic renal failure (CRF) in the presence of hypertensive nephrosclerosis is yet to ...
28,812
Elevation of plasma von Willebrand factor and tumor necrosis factor-a in obese subjects and their reduction by the low molecular weight heparin tinzaparin.
Increased plasma-soluble von Willebrand factor (vWF) level, a marker of vascular endothelial cell dysfunction, is a predictor of atherosclerotic cardiovascular disease. We compared associations between vWF level and markers of inflammation as well as the effects of LMWH in obese as compared to healthy human subjects.</...
28,813
Are we managing primary upper limb deep venous thrombosis aggressively enough in the district?
The objective of this retrospective study was to analyse risk factors, management and outcome of primary upper limb deep venous thrombosis (ULDVT, Paget von Schroetter syndrome) in 4 district hospitals.</AbstractText>The study group audited between May 1995 and January 2004 comprised of 24 patients with primary ULDVTs ...
28,814
Risk assessment model for venothromboembolism in post-hospitalized patients.
Venothromboembolism (VTE) is an important condition in hospitalized patients accounting for significant morbidity and mortality, and the risk of VTE often continues post-hospitalization. Although risk assessment models have been developed to predict the risk of deep venous thrombosis (DVT) in hospitalized patients, no ...
28,815
Fusobacterium necrophorum infection associated with portal vein thrombosis.
This report describes a patient without obvious upper respiratory tract or gastrointestinal infection who developed portal vein thrombosis secondary to Fusobacterium necrophorum septicaemia. The patient responded well to systemic antibiotic therapy. The implications of F. necrophorum infection caudal to the head are di...
28,816
Role of thrombophilic gene polymorphisms in branch retinal vein occlusion.
Branch retinal vein occlusion (BRVO) is a common cause of severe visual loss. Numerous risk factors, including arterial hypertension, diabetes mellitus, and arteriosclerosis, have been identified. Gene polymorphisms affecting hemostasis may also play a role in the pathogenesis of BRVO. The present study was therefore d...
28,817
Fondaparinux sodium: a review of its use in the treatment of acute venous thromboembolism.
Fondaparinux sodium (fondaparinux) is a synthetic sulfated pentasaccharide anticoagulant developed from the antithrombin binding moiety of heparin. Through the activation of antithrombin it inhibits Factor Xa, the activation of thrombin, and the subsequent coagulation cascade. Fondaparinux is approved in Europe and the...
28,818
Inhibition of Factor Xa : a potential target for the development of new anticoagulants.
Anticoagulant therapy plays an important role in the prevention and treatment of pathologic arterial and venous thrombosis. There is increasing enthusiasm in the inhibition of Factor Xa as a target to achieve therapeutic anticoagulation because of its central and 'upstream' position in the coagulation process. The indi...
28,819
Optical coherence tomography findings after an intravitreal injection of bevacizumab (avastin) for macular edema from central retinal vein occlusion.
To determine whether bevacizumab could improve visual acuity and optical coherence tomography outcomes in a patient with macular edema from central retinal vein occlusion, an intravitreal injection of bevacizumab (1.0 mg) was given. Prior intravitreal injections of triamcinolone acetonide resulted in vision improvement...
28,820
The fentanyl HCl patient-controlled transdermal system (PCTS): an alternative to intravenous patient-controlled analgesia in the postoperative setting.
Inadequate pain control in the postoperative period not only contributes to patient discomfort, but also causes physiological changes that may result in increased risk of myocardial ischaemia, deep vein thrombosis and pulmonary embolism. These events complicate postoperative recovery and may lead to longer hospital sta...
28,821
Risk of cerebral venous thrombosis and novel gene polymorphisms of the coagulation and fibrinolytic systems.
Genetic thrombophilic conditions such as those associated with Factor V Leiden (FVL) and the prothrombin mutant (PT G20210A) have been identified as risk factors for cerebral venous thrombosis (CVT). Recently, a single nucleotide polymorphism (SNP) of the thrombin activatable fibrinolysis inhibitor (TAFI G-438A) has be...
28,822
Pregnancy and stroke.
The risks of ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage are not increased in the 9 months of gestation except for a high risk in the 2 days prior and 1 day postpartum. The remaining 6 weeks postpartum also have an increased risk of ischemic stroke and intracerebral hemorrhage, though less th...
28,823
Hypercoagulable states and stroke: a selective review.
Blood disorders have been implicated in approximately 5% to 10% of ischemic stroke, with an increased frequency in younger patients. Most disorders are associated with an increased thrombotic tendency and, therefore, an increased risk of ischemic stroke. Less commonly, a bleeding diathesis may predispose a patient to i...
28,824
Unusual complication of central venous catheter in hemodialysis.
A case of a partial rupture of a cuffed central venous catheter (CVC) implanted in the femoral vein with the purpose of being used for chronic hemodialysis is described in a 74-year-old female patient. Of relevance is that the CVC described was from the same manufacturer as the previous one that had lasted 12 years.
28,825
Anticoagulant treatment and survival in cancer patients. The evidence from clinical studies.
The association between cancer and an increased incidence of venous thromboembolism (Trousseau syndrome) is well characterized and recent studies have shown that the hemostatic system plays a key role at different stages in the process of tumorigenesis. Anticoagulant drugs therefore appear to be an attractive strategy ...
28,826
Synthesis, antiplatelet and antithrombotic activities of new 2-substituted benzopyrano[4,3-d]pyrimidin-4-cycloamines and 4-amino/cycloamino-benzopyrano[4,3-d]pyrimidin-5-ones.
Atherothrombotic coronary artery disease, associated with deep vein thrombosis, is one of the most common causes of death worldwide. Recently, antiplatelet combination therapy using agents with different mechanisms of action, such as aspirin, dipyridamole, and thienopyridines, seems to be an attractive preventive appro...
28,827
Resection of the abdominal inferior vena cava for complicated renal cell carcinoma with tumour thrombus.
To describe our experience of excising the inferior vena cava (IVC) without a graft; en bloc resection of a renal cell carcinoma (RCC) with the renal vein and vena cava tumour thrombus and a segment of the entire abdominal IVC is technically feasible, but traditionally, after resection, attempts are made to restore con...
28,828
Cost effectiveness of dalteparin for preventing venous thromboembolism in abdominal surgery.
Patients undergoing abdominal surgeries face substantial risk of experiencing venous thromboembolic events in the perioperative period. The low-molecular-weight heparin dalteparin sodium is clinically effective in reducing the incidence of venous thromboembolism (VTE) in these patients. Dalteparin may be used in low (2...
28,829
Prevalence of inherited prothrombotic abnormalities and central venous catheter-related thrombosis in haematopoietic stem cell transplants recipients.
In this prospective study, we assessed the incidence of central venous catheter (CVC)-related thrombosis in haematopoietic stem cell transplant (HSCT) recipients. We determined the contribution of inherited prothrombotic abnormalities in blood coagulation to CVC-related thrombosis in these patients. The study was condu...
28,830
Experience with the recovery filter as a retrievable inferior vena cava filter.
This study evaluates clinical experience with the Recovery filter as a retrievable inferior vena cava (IVC) filter.</AbstractText>One hundred seven Recovery filters were placed in 106 patients with an initial clinical indication for temporary caval filtration. Patients were followed up to assess filter efficacy, compli...
28,831
Management studies using a combination of D-dimer test result and clinical probability to rule out venous thromboembolism: a systematic review.
While the number of patients with suspected venous thromboembolism (VTE) referred to hospital emergency units increases, the proportion in whom the diagnosis can be confirmed is decreasing. A more efficient but safe diagnostic strategy is needed.</AbstractText>To evaluate the safety of withholding anticoagulant therapy...
28,832
POEMS syndrome with venous sinus thrombosis and visual failure: a case report.
POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein and skin changes) syndrome is a multisystem disorder associated with plasma cell dyscrasia. Other clinical signs include clubbing of the fingers, edema, papilledema etc. Although papilledema and increased intracranial pressure are common features, their cau...
28,833
[Diagnosis and treatment of mesenteric venous thrombosis early after operation].
To analyze the clinical characteristics diagnosis and treatment of patients with mesenteric venous thrombosis early after operation.</AbstractText>A retrospective study was performed on the clinical data of 7 patients with mesenteric venous thrombosis early after operation from 1990 to 2004.</AbstractText>Patients had ...
28,834
Homonymous hemianopia caused by occipital lobe infarction in heparin-induced thrombocytopenia and thrombosis syndrome.
A 73-year-old woman developed mental confusion and finger pain after treatment with enoxaparin following arthroplasty. A platelet count was 163,000/microL. Because digital embolism was suspected, she was emergently treated with heparin and recombinant tissue plasminogen activator (rTPA). During rTPA infusion, she repor...
28,835
Lemierre's and Lemierre's-like syndromes in children: survival and thromboembolic outcomes.
Lemierre's syndrome, or jugular vein thrombosis (JVT) associated with anaerobic infection of the head and neck and frequently complicated by septic pulmonary embolism (PE), has historically been described as a disease of young adults. In recent years, an increasing number of case reports of childhood Lemierre's syndrom...
28,836
Influence of angiotensin converting enzyme insertion/deletion polymorphism on long-term total graft occlusion after coronary artery bypass surgery.
The renin-angiotensin system has a very important role in coronary thrombosis and restenosis. Plasma angiotensin converting enzyme (ACE) activity is associated with an insertion/deletion polymorphism in the gene coding for ACE. It is known that there is a strong correlation between ACE DD and atherosclerosis. However, ...
28,837
Pancreatico-renal composite transplant: a new technique designed to decrease pancreatic graft thrombosis.
Pancreas graft thrombosis continues to be a major cause of graft loss. The removal of the donor spleen is accompanied by a significant reduction in pancreas graft blood flow. It is likely that reduced blood flow contributes to thrombosis in concert with other factors. We present a case of simultaneous pancreas and dual...
28,838
Unusual findings in brain biopsies of two patients with acute magnetic resonance imaging lesions associated with focal seizures.
Patients with focal seizures often have magnetic resonance imaging (MRI) abnormalities in the brain region of their presumed seizure focus. Neoplasms, ischemic infarctions, inflammatory processes, and other specific pathologic entities have been diagnosed by biopsies of such MRI abnormalities. Two patients with this pr...
28,839
Adrenal crisis due to bilateral adrenal hemorrhage in primary antiphospholipid syndrome.
The authors report a case of a 56-year-old Thai woman with a history of recurrent venous thrombosis, spontaneous abortion and Graves' disease who presented with bilateral flank pain, nausea, vomiting and low-grade fever followed by hypotension. Adrenal crisis from bilateral adrenal hemorrhage was diagnosed by a low ser...
28,840
Indirect CT venography of the abdominal cavity and lower limbs in patients with the suspicion of pulmonary embolism--indications, technique, diagnostic possibilities.
Multi-slice computed tomography has become the main method to diagnose and evaluate the intensity of acute pulmonary embolism (PE). The most common cause of PE is thrombosis of veins of the lower limbs and pelvis. The paper presents various aspects of the use of combined pulmonary artery arteriography and indirect veno...
28,841
Successful treatment of giant right coronary artery aneurysm mimicking right atrium thrombus--a case report.
Coronary artery aneurysms are very rare abnormalities in patients undergoing coronary angiography. Clinical manifestation is usually that of coronary artery disease, and acute myocardial infarction. We present the case of a patient admitted to the Department of Cardiac Surgery due to coronary artery disease and the pre...
28,842
Pre-operative management of patients on drugs affecting blood coagulation.
The aim of the study is to present practical guidelines for the pre-operative management of patients taking commonly applied drugs that affect blood coagulation. In hospital practice it is the responsibility of an internist to evaluate the patient's condition before the patient undergoes surgery. Among the patients con...
28,843
A new model of reversible sinus sagittalis superior thrombosis in the rat: magnetic resonance imaging changes.
The causes of cerebral sinus and vein occlusion and the accompanying parenchymal changes remain largely unexplained. The clinical variability and low incidence of the disease complicate systematic clinical investigations. Animal studies are indispensable; however, existing animal models of sinus thrombosis do not allow...
28,844
Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma' levels.
We investigated the association between haplotypes of fibrinogen alpha (FGA), beta (FGB), and gamma (FGG), total fibrinogen levels, fibrinogen gamma' (gammaA/gamma' plus gamma'/gamma') levels, and risk for deep venous thrombosis. In a population-based case-control study, the Leiden Thrombophilia Study, we typed 15 hapl...
28,845
Homocysteine, MTHFR C677T gene polymorphism, folic acid and vitamin B 12 in patients with retinal vein occlusion.
Many available data have suggested that hyperhomocysteinaemia, an established independent risk factor for thrombosis (arterial and venous), may be associated with an increased risk of retinal vein occlusion (RVO).</AbstractText>To evaluate homocysteine metabolism in consecutive caucasian patients affected by RVO from N...
28,846
Ximelagatran--recent comparisons with warfarin.
Recently, ximelagatran and warfarin have been compared for stroke prevention in the Stroke Prevention using an Oral Thrombin Inhibitor in Atrial Fibrillation (SPORTIF) V trial in patients with non-valvular atrial fibrillation, and for the treatment of deep vein thrombosis in the Thrombin Inhibitor in Venous Thromboembo...
28,847
[Postoperative vessel thrombosis and its management after free flap transfers in head and neck region].
To analyze the rate of postoperative vessel thrombosis and its management after free tissue transfers in head and neck region.</AbstractText>Eight hundred and forty-nine consecutive free flap transfers were performed from May 1999 to September 2004. Among them, the flaps with postoperative vessel thrombosis were select...
28,848
Bilateral upper extremity thrombophlebitis related to intravenous amiodarone: a case report.
A 47-year-old male had bilateral upper extremity thrombophlebitis after use of intravenous amiodarone for sustained ventricular tachycardia complicating myocardial infarction. Intravenous amiodarone has been widely used since it was introduced 20 years ago for severe intractable arrhythmias. Superficial thrombophlebiti...
28,849
Pharmacological thrombolysis: one more weapon for free-flap salvage.
Despite the high success rate of free-tissue transfer, thrombosis still complicates 5-30% of cases. Meticoulous technique, careful vessel selection, and pharmacological prophylaxis are not always enough to avoid thrombosis. Early diagnosis and reintervention provide the only way to salvage a thrombosed free flap, in ca...
28,850
[Contra indications of sclerotherapy, update 2005].
Modern sclerotherapy, using ultrasound guidance and foam sclerosants, is a reference treatment of varices of the lower limbs. Like all other techniques it should be employed in the safest, precisely described and reproducible conditions. Therefore, its contra indications must be clearly known.</AbstractText>Contra indi...
28,851
[Principles of hemodynamics and sonographic techniques for the evaluation of veins of the neck and limbs].
Deep venous thrombosis and venous insufficiency are now easily diagnosed with US imaging. US allows anatomic evaluation of the vessel walls and dynamic evaluation of flow velocities. Knowledge of vascular anatomy and physiology is required to interpret US data. The sensitivity of US for the diagnosis of deep venous thr...
28,852
[Headache in patients with cerebral venous thrombosis].
Headache is the most frequent symptom of cerebral venous thrombosis. They do not have particular characteristics and can mimic other numerous varieties of headache. Frequently associated with other neurological symptoms, such as intracranial hypertension, seizures, focal deficits or disorders of consciousness, they are...
28,853
Retinal vascular occlusion in patients infected with human immunodeficiency virus.
To describe the clinical features of retinal vascular occlusions (macrovasculopathy) and the proportion of affected patients with human immunodeficiency virus (HIV) infection.</AbstractText>Retrospective chart review of all HIV-infected individuals with retinal vascular occlusions seen at a single tertiary care clinic ...
28,854
Characteristics of visual field defects by scanning laser ophthalmoscope microperimetry after radial optic neurotomy for central retinal vein occlusion.
To evaluate visual field defects after radial optic neurotomy (RON) for the treatment of central retinal vein occlusion (CRVO) by using scanning laser ophthalmoscope microperimetry.</AbstractText>Thirteen eyes of 13 patients with severe vision loss (&lt; or = 20/200) from CRVO who underwent pars plana vitrectomy and RO...
28,855
Prevention of venous thromboembolic disease after total hip and knee arthroplasty.
Patients undergoing total hip and knee arthroplasty are at increased risk for the development of venous thromboembolic disease, and there is general agreement that these patients require prophylaxis. The selection of a prophylactic agent involves a balance between efficacy and safety and often needs to be individualize...
28,856
Accelerometer based calf muscle pump activity monitoring.
Long distance travel is associated with increased risk of deep vein thrombosis (DVT). There is an increased risk of travel related DVT in passengers with a predisposition to thrombosis. Assisting blood circulation in the lower limb will reduce the risk of DVT. Leg exercises are recommended as a DVT preventative measure...
28,857
Pulsatile tinnitus in a 16-year-old patient.
This report describes a child presenting with pulsatile tinnitus, most likely resulting from increased intracranial hypertension secondary to cerebral venous thrombosis. He was found to be homozygous for a prothrombin gene (G20210A) mutation as well as heterozygous for a factor V Leiden mutation. Physicians need to pur...
28,858
Trans-tenon retrobulbar triamcinolone injection for macular edema associated with branch retinal vein occlusion remaining after vitrectomy.
To evaluate the effectiveness and safety of trans-Tenon retrobulbar triamcinolone injection for macular edema associated with branch retinal vein occlusion (BRVO) after vitrectomy.</AbstractText>Prospective interventional case series.</AbstractText>The study included 20 eyes of 20 patients with BRVO, characterized by m...
28,859
Incidence and risk factors of venous thromboembolism (VTD) in patients with amyloidosis.
Coagulation problems in amyloidosis are historically associated with bleeding tendencies (mostly Factor X abnormalities). Increased clotting was observed in isolated cases diagnosed with low-grade disseminated intravascular coagulation (DIC). Problem of venous thromboembolic disaease (VTD) in amyloidosis was not system...
28,860
Congenital insensitivity to pain with Anhidrosis (NTRK1 mutation) and early onset renal disease: clinical report on three sibs with a 25-year follow-up in one of them.
Congenital insensitivity to pain with anhidrosis (CIPA) is an autosomal recessive disorder caused by mutations in the neurotrophic tyrosine receptor kinase 1 (NTRK1) gene which encodes the receptor for nerve growth factor (NGF). We report the clinical course in three sibs with CIPA and proven NTRK1 gene mutations with ...
28,861
[Protein Z: a new factor of thrombophilia?].
Sometimes, in front of a clinical setting of thrombophilia, the biological findings are helpless. Therefore we suggest to test a protein Z deficiency.</AbstractText>Protein Z is a vitamin-K dependent protein forming a complex with the Z protein-dependent protease inhibitor for inhibiting the activated factor X; so prot...
28,862
Small bowel varices from neuroendocrine tumor of the pancreas.
Small bowel varices (SBVs) are a rare but important cause of gastrointestinal (GI) bleeding. We present a case of SBVs caused by superior mesenteric vein thrombosis from a large neuroendocrine tumor of the pancreas. This patient presented with GI bleeding. A computed tomography scan showed an incidental hypervascular m...
28,863
[Effect of ulinastatin on human blood coagulation and platelet aggregation in orthopaedic surgery].
To investigate the effect of ulinastatin (UTI) on human blood coagulation and platelet aggregation in orthopaedic surgery.</AbstractText>Thirty ASA I-II patients without blood dyscrasia and blood coagulation obstacle were randomly divided into two groups: Group I (UTI group, n=15) in which patients received UTI 5000 U/...
28,864
Imaging and radiological interventions of portal vein thrombosis.
Portal vein thrombosis (PVT) is diagnosed by imaging methods. Once diagnosed by means of ultrasound, Doppler ultrasound can be performed to distinguish between a benign and malignant thrombus. If further information is required, magnetic resonance angiography or contrast-enhanced computed tomography is the next step, a...
28,865
[Branch retinal vein occlusion treated by intravitreal triamcinolone].
Five eyes with branch retinal vein occlusion (BRVO) were treated with intravitreal injection of 4 mg of triamcinolone. Four cases showed good visual acuity and macular thickness evolution after one dose. The remaining one case suffered a relapse three months later. Therefore a second injection was performed in that cas...
28,866
The relationship of the factor V Leiden mutation and pregnancy outcomes for mother and fetus.<Pagination><StartPage>517</StartPage><EndPage>524</EndPage><MedlinePgn>517-24</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">We sought to estimate the frequency of pregnancy-related ...
Modern issues of the portal vein resection while hepatectomy conduction are enlighten. The indications for resection of region of the portal vein branches confluence were substantiated, various methods of portoplasty were depicted. New methods of the portal tract passability restoration in discrepancy of diameters of t...
28,867
Percutaneous therapy for deep vein reflux.
At present, there are no widely accepted surgical or percutaneous treatment options for chronic venous insufficiency of the deep venous system. The small intestinal submucosa square stent bicuspid venous valve (BVV) has shown the most promising results of artificial venous valves developed to date. In experimental long...
28,868
Percutaneous options for acute deep vein thrombosis.
Anticoagulant therapy is associated with poor late limb outcomes in many patients with deep vein thrombosis (DVT). Because systemic thrombolysis and surgical thrombectomy have inherent limitations, image-guided percutaneous thrombus removal is currently favored. Pharmacologic thrombolysis is effective in removing throm...
28,869
Lower extremity venous anatomy.
The lower extremity venous system includes the superficial, deep, and perforating veins. The antegrade flow of blood within these veins is ensured by a system of muscular venous pumps and bicuspid valves. Dysfunction of the system may result from degeneration of the vein wall, post-thrombotic valvular damage, chronic v...
28,870
Crohn's disease among Saudis in Al-Gassim region.
Crohn's disease is being increasingly reported from Saudi Arabia and information about its pattern is still accumulating.</AbstractText>To describe and classify the disease and assess the response to therapy in patients referred to a tertiary care centre in Gassim region, Kingdom of Saudi Arabia (KSA).</AbstractText>Fi...
28,871
Determining optimum management of descending necrotizing mediastinitis with CT; experience with 32 cases.
To determine the value of helical computed tomography (CT) in the diagnosis, management and outcome of patients suspected of having descending necrotizing mediastinitis (DNM). Thirty-two patients with suspected DNM were submitted to contrast-enhanced single detector-row helical CT, four detector-row CT and 16 detector-...
28,872
Thrombosis and priapism in a patient with Henoch-Schonlein purpura.
Henoch-Sch&#xf6;nlein purpura (HSP) belongs to the category of systemic small-vessel vasculitis. Although long-term outcome is generally good, serious complications may occur. Thrombosis and priapism have been reported only as extremely rare complications of HSP. We describe a 37-year-old man who developed recurrent th...
28,873
[Bilateral renal angiomyolipomas with a thrombus in the inferior caval vein. Rare growth pattern of a benign tumor].
Renal angiomyolipomas are mesenchymal tumors that are composed of fat tissue, smooth muscle cells and vessels. These are benign tumors, but in rare cases they show a more aggressive growth pattern with invasion into the venous system but without revealing any signs of malignancy. We report a new case of bilateral renal...
28,874
Intravitreal levels of vascular endothelial growth factor and interleukin-6 are correlated with macular edema in branch retinal vein occlusion.
To investigate whether vascular endothelial growth factor (VEGF) or interleukin-6 (IL-6) contributes to the pathogenesis of macular edema in eyes with branch retinal vein occlusion (BRVO), the correlations between these factors were investigated.</AbstractText>We studied 25 patients suffering from macular edema with BR...
28,875
Intramuscular midazolam vs intravenous diazepam for acute seizures.
To determine effectiveness of intramuscular midazolam to control acute seizures in children as compared to intravenous diazepam.</AbstractText>115 children in the age group of 1 month to 12 years who presented with acute convulsions were enrolled in the study. Patients who already had an intravenous access present were...
28,876
Post-thrombotic syndrome after total hip or knee arthroplasty: incidence in patients with asymptomatic deep venous thrombosis.
To measure the risk of developing signs of post-thrombotic syndrome 15 to 24 months after total hip or knee arthroplasty in patients with asymptomatic deep venous thrombosis (DVT).</AbstractText>A total of 85 total knee arthroplasty patients and 47 total hip arthroplasty patients were postoperatively screened for asymp...
28,877
Disseminated intravascular coagulation in an ambulatory young woman.
We are reporting the case of an ambulatory young woman with a 10-year history of recurrent venous thrombosis who presented to us with diffuse intravascular coagulation (DIC). After excluding the recognized causes of DIC, we examined the possibility that her clinically quiescent ulcerative colitis might be the underlyin...
28,878
Understanding the antiphospholipid syndrome and its treatment.
The antiphospholipid syndrome (APS) is a clinicopathologic disorder characterized by the persistent presence of anticardiolipin antibodies, lupus anticoagulants, or both in the plasma of patients with arterial or venous thrombosis or obstetric complications. The antiphospholipid antibodies involved in this syndrome hav...
28,879
Action to reduce incidence of venous thromboembolism.
Despite the availability of well-known and effective prophylactic measures, between 25,000 and 32,000 people in England each year contract a fatal venous thromboembolism while in hospital. This article highlights concerns raised by the House of Commons inquiry into this problem and outlines the Departments of Health's ...
28,880
Computed tomography findings in 10 cases of iliac vein compression (May-Thurner) syndrome.
To present the computed tomography (CT) findings for the iliac veins of 10 patients who had left-sided lower extremity deep vein thrombosis due to iliac vein compression syndrome.</AbstractText>The CT findings for 10 cases of left-sided acute or chronic deep vein thrombosis caused by iliac vein compression syndrome wer...
28,881
Thrombosis in inflammatory bowel diseases: role of inherited thrombophilia.
Inflammatory bowel diseases (IBD) are characterized by an increased risk for venous and arterial thrombosis. Although the pathogenetic mechanisms of this predisposition are unclear, a possible role of inherited risk factors for thrombosis in determining this predisposition has been suggested.</AbstractText>To evaluate ...
28,882
Stroke and pulmonary thromboembolism after a long flight.
In the economy class syndrome (ECS) the patient presents a deep venous thrombosis (DVT) with or without pulmonary thromboembolism (PTE) during or after a long trip as a result of prolonged immobilization. Economy class stroke syndrome is an infrequent ECS variant in which ischemic stroke is associated with a patent for...
28,883
Is physical training contraindicated in patients with deep vein thrombosis during cardiac rehabilitation?
Deep vein thrombosis is a potential complication in patients admitted to cardiac rehabilitation programs after acute coronary syndromes, episodes of acute congestive heart failure, and cardiac revascularization. A common clinical problem in these patients is to decide whether to start or continue physical training or n...
28,884
Management of thrombosis in antiphospholipid syndrome and systemic lupus erythematosus in pregnancy.
Pregnancy is a high risk period for thrombosis in women with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) with antiphospholipid antibodies (aPL). Thrombosis may affect the mother, both in the venous and arterial beds, and also have a role in pregnancy loss. Thromboprophylaxis thus is warranted...
28,885
Mono-organic versus multi-organic involvement in primary antiphospholipid syndrome.
The prevalence of mono-organic and multi-organic involvement during long-term follow-up in patients with primary antiphospholipid syndrome (pAPS) was investigated. We studied 60 pAPS patients followed up at least 5 years. Patients with associated systemic lupus erythematosus were excluded. All patients received oral an...
28,886
Avidity of anti-beta2-glycoprotein I and thrombosis or pregnancy loss in patients with antiphospholipid syndrome.
We aimed to evaluate avidity of anti-beta(2)-glycoprotein I antibodies (anti-beta(2)-GPIs) in patients with antiphospholipid syndrome (APS) at the time of acute thrombotic events or pregnancy loss as compared with clinical event-free periods. To do so, 69 sera samples from 16 patients (6 with primary APS and 10 with AP...
28,887
Deep venous thrombosis: withholding anticoagulation therapy after negative complete lower limb US findings.
To establish the safety of withholding anticoagulation therapy after negative findings at a complete lower limb ultrasonographic (US) examination of the symptomatic leg for suspected deep venous thrombosis (DVT).</AbstractText>Regional ethics committee approval and patient consent were obtained. A total of 542 consecut...
28,888
Catheter directed thrombolysis for treatment of ilio-femoral deep venous thrombosis is durable, preserves venous valve function and may prevent chronic venous insufficiency.
To investigate the results of catheter directed thrombolysis offered to patients with acute femoro-iliac deep venous thrombosis (DVT).</AbstractText>Retrospective analysis of all patients treated with this modality at Gentofte Hospital until December 2003.</AbstractText>Forty-five consecutive patients treated between J...
28,889
Long-term mortality in patients with thrombosis of the inferior vena cava, iliac and femoral veins.
To assess the long-term mortality in patients with thrombosis of the vena cava, iliac and femoral veins.</AbstractText>Registry study.</AbstractText>Between 1992 and 2000, 212 consecutive patients with acute pelvic vein thrombosis diagnosed by duplex sonography were examined by magnetic resonance imaging (MRI) to deter...
28,890
Endovascular management of acute deep vein thrombosis.
The goals of successful management of deep vein thrombosis (DVT) include relief of acute symptoms with restoration of venous patency, prevention of clot propagation and subsequent pulmonary embolism, and maintenance of venous valvular function. Valvular incompetence is the leading cause of postthrombotic syndrome (PTS)...
28,891
Heparin-induced thrombocytopenia: clinical manifestations and management strategies.
Thrombocytopenia is a relatively frequent and usually benign clinical complication of heparin therapy. However, some patients receiving heparin and heparin-based products experience an immune-mediated reaction due to the development of heparin-induced antibodies. This reaction leads to a highly specific and paradoxical...
28,892
Anticoagulants in the treatment of deep vein thrombosis.
Intravenous (IV) infusion of unfractionated heparin (UFH) followed by oral administration of warfarin remains the cornerstone of clinical treatment of deep vein thrombosis (DVT). Results from numerous clinical trials demonstrate that subcutaneously administered low-molecular-weight heparin (LMWH) is at least as effecti...
28,893
Diagnostic assessment of deep vein thrombosis and pulmonary embolism.
Venous thromboembolism (VTE) is a common disorder that can lead to substantial morbidity and mortality through the clinical manifestations of deep vein thrombosis (DVT) and pulmonary embolism (PE). Although rapid diagnosis and treatment are critical in preventing PE, mortality and major morbidity due to conditions such...
28,894
[Late thrombosis of a drug-eluting coronary stent after antiplatelet therapy discontinuation].
We reported the late thrombosis of a drug-eluting coronary stent related to discontinuation of antiplatelet therapy for venous surgery of the right leg more than half and a year after its implantation. After this acute myocardial infarction, a cardiac assistance device has to be used as a bridge to transplantation beca...
28,895
Catheter fracture and cardiac migration--an unusual fracture site of totally implantable venous devices: report of two cases.
Totally implantable venous devices (TIVDs) are used increasingly in patients with cancers and other debilitating diseases requiring long-term chemotherapy, total parental nutrition, and fluid replacement. The TIVDs are surgically inserted and fixed in the soft tissues of the chest wall to prevent infection and accident...
28,896
Ximelagatran in the clinic: practical management of patients.
Several case studies are briefly introduced, followed by a description of the clinical problem from an epidemiological point of view. The evidence for established management strategies is reviewed and, finally, practical handling of the case is considered.
28,897
Treating patients with venous thromboembolism: initial strategies and long-term secondary prevention.
Therapy for venous thromboembolism (VTE) currently involves a minimum of 3 months of anticoagulation. After cessation of therapy, however, recurrent venous thrombosis occurs at rates of 6 to 9% per year. Clinical trials have demonstrated the benefits of extending anticoagulation beyond 3 months for the prevention of re...
28,898
Ximelagatran for the prevention of venous thromboembolism following elective hip or knee replacement surgery.
Patients undergoing major lower-extremity orthopedic surgery such as total hip replacement (THR) and total knee replacement (TKR) are at an increased risk of venous thromboembolism (VTE). Routine prophylaxis is necessary to reduce the risk of deep vein thrombosis (DVT), which may progress to potentially fatal pulmonary...
28,899
Mechanism of action of the oral direct thrombin inhibitor ximelagatran.
Thrombin plays a central role in thrombus formation through its conversion of fibrinogen to fibrin and activation of platelets as well as amplifying its own generation by feedback activation via factors V, VIII, and XI. Consequently, thrombin represents a logical and promising target for therapeutic interventions again...