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29,100 | Inferior vena cava duplication and deep venous thrombosis: case report and review of literature. | Duplications of the inferior vena cava (IVC) are seen with an incidence of 0.2% to 3.0%. Duplications causing symptoms are rare, with only six reported cases of IVC duplication associated with a deep venous thrombosis. We present a 78-year-old caucasian woman with an IVC duplication who developed a deep venous thrombos... |
29,101 | Ultrasound criteria for embologenicity of venous thrombosis. | Altogether 136 patients aged 17 to 79 years with a diagnosis of acute and subacute thrombosis of lower limb deep veins were examined by duplex scanning in order to derive the ultrasound criteria for embologenicity of inferior vena cava thrombosis. The authors evaluated thrombosis standing (from the emergence of the fir... |
29,102 | [Klinefelter's syndrome associated with mixed connective tissue disease (Sharp's syndrome) and thrombophilia with postthrombotic syndrome]. | A 43-year-old male with eunuchoid body proportions and a history of deep venous thromboses in the right leg presented with recurrent ulcers in the right perimalleolar region for 6 years. Karyotyping revealed a 47 XXY Klinefelter's syndrome, while serologic testing showed protein S deficiency, hyperhomocysteinemia and p... |
29,103 | [A case of portal vein thrombosis associated with acute pancreatitis and cholangitis]. | Portal vein thrombosis is a rare complication accompanied with acute pancreatitis or cholangitis/cholecystitis. The main pathogenesis of portal vein thrombosis in pancreatitis or cholangitis/cholecystitis are suggested to be venous compression by pseudocyst and an imbalance between the blood coagulation and fibrinolysi... |
29,104 | Systemic lupus erythematosus in a multiethnic cohort (LUMINA): XXVIII. Factors predictive of thrombotic events. | To determine the relationship between the presence of antiphospholipid (aPL) antibodies, hydroxychloroquine use and the occurrence of thrombotic events in patients with systemic lupus erythematosus (SLE).</AbstractText>Four hundred and forty-two SLE patients from the LUMINA (Lupus in Minorities: Nature vs Nurture) coho... |
29,105 | Catheter-related thrombosis in hematologic patients. | For many years central venous catheters (CVC) have been utilized to monitor hemodynamics and to deliver parenteral nutrition, blood products, pharmacological therapies or infusion fluids. Recently, CVC use has greatly increased with significant impact on the administration of chemotherapy, stem cell transplantation and... |
29,106 | Drug-related thrombosis in hematologic malignancies. | Cancer patients are at increased risk for thrombosis. Among the predisposing factors for the hemostatic imbalance, drugs have a definite role. Induction of thrombosis by drugs involves a variety of mechanisms: Enhancement of procoagulant activity, reduction in anticoagulants synthesis, stimulation of platelet aggregati... |
29,107 | Thrombosis in children with hematologic malignancies. | This review is based on pediatric reports (- January 2004) on the presence of symptomatic thrombosis in children with hematologic malignancies, mainly acute lymphoblastic leukemia, treated with different treatment protocols and associated with acquired and inherited prothrombotic risk factors (factor V G1691A, factor G... |
29,108 | [Vascular complications of pancreatitis]. | Vascular complications of pancreatitis are infrequent but important clinical problems because of their higher mortality. Pseudocysts that appear in 5%-50% patients with pancreatitis can erode adjacent vessels with hemorrhage, venous thrombosis and pseudoaneurysms. Increase in pressure within pseudoaneurysm can give ris... |
29,109 | [Prognostic value of syncope in the presentation of pulmonary embolism]. | Although the prognostic value of syncope has not been specifically addressed, it has generally been considered an indicator of poor prognosis in pulmonary embolism. The objective of this study was to carry out a prospective evaluation of the risk of recurrence and/or death in patients with pulmonary embolism that prese... |
29,110 | [Apoptosis of pathological tissues and expression of apoptosis-related genes in hepatic venous stricture Budd-Chiari syndrome]. | To investigate the pathogenesis of hepatic venous stricture Budd-Chiari syndrome from the point of view of hepatic venous intimal proliferation, apoptosis and apoptosis-related genes.</AbstractText>Thirty samples resected from patients with hepatic venous stricture Budd-Chiari syndrome and 21 samples of normal hepatic ... |
29,111 | Comparison of incidence/risk of venous thromboembolism (VTE) among selected clinical and hereditary risk markers: a community-based cohort study. | Little information is available from community-based long-term VTE cohort studies to compare the absolute thrombosis risk of established clinical and genetic risk factors.</AbstractText>The occurrence of venous thromboembolism (VTE) was observed during a 10-year observation period in the BAvarian ThromboEmbolic Risk (B... |
29,112 | [Mesenteric venous trombosis and pregnancy--a case report and a short review of the problem]. | Mesenteric venous thrombosis is extremely rare surgical pathology during pregnancy and frequently is associated with hemoglobinopathies beta-thalassemia, congenital defects of the coagulation and antiphospholipide syndrome. It has nontypical clinical appearance, which hardens the timely diagnosis and the adequate surgi... |
29,113 | Meta-analysis: The value of clinical assessment in the diagnosis of deep venous thrombosis. | Clinical assessment of suspected deep venous thrombosis (DVT) should be based on systematically evaluated evidence.</AbstractText>To determine whether clinical findings, risk scores, and physicians' empirical judgments affect the likelihood of detecting DVT on definitive testing.</AbstractText>MEDLINE, EMBASE, CINAHL, ... |
29,114 | The Wells rule does not adequately rule out deep venous thrombosis in primary care patients. | Using data from secondary care outpatients, Wells and colleagues developed a diagnostic rule to estimate the probability of the presence of deep venous thrombosis (DVT). The accuracy of the Wells rule has not been properly validated for use in primary care patients in whom DVT is suspected.</AbstractText>To validate th... |
29,115 | [Assessment of hemodynamics in patients with Budd-Chiari syndrome after interventional treatment]. | To study the changes in morphology of liver and spleen and hemodynamics of the patients with Budd-Chiari syndrome (BCS) after interventional treatment.</AbstractText>The dimensions of liver and spleen were detected by routine ultrasonography in 30 normal control subjects and 256 BCS patients before and after inventiona... |
29,116 | Low-molecular-weight heparins for the treatment of acute coronary syndrome and venous thromboembolism in patients with chronic renal insufficiency. | The clinical management of patients with renal insufficiency who develop an acute coronary syndrome or venous thromboembolism is a common clinical scenario that is problematic because of the lack of well-designed randomized trials assessing management strategies in such patients. Impaired renal function is common in pa... |
29,117 | Macronodular hepatic tuberculosis associated with portal vein thrombosis and portal hypertension. | Tuberculosis (TB) of the liver is usually associated with miliary spread. Macronodular TB of the liver is rare. A case of macronodular TB of the liver in a 31-year-old woman causing portal vein thrombosis and portal hypertension is presented. Ultrasound and CT appearances are described. There was coexistent ileo-caecal... |
29,118 | Sensitivity to activated protein C in patients with deep vein thrombosis during early puerperium period. | In this study, we used an endogenous thrombin potential (ETP)-based assay to examine the response to activated protein C (APC) during early puerperium of 6 Japanese patients of deep vein thrombosis (DVT) and pulmonary embolism (PE) without a history of familial thrombophilia or antiphospholipid syndrome.</AbstractText>... |
29,119 | Serum acute phase protein concentrations after hysterectomy with and without low-molecular-weight heparin thrombosis prophylaxis. | Background. Low-molecular-weight heparin (LMWH) is recommended for venous thrombosis prophylaxis. There are several lines of evidence that heparins exhibit anti-inflammatory properties in addition to their anticoagulant activity. Therefore, we decided to estimate the concentrations of C-reactive protein (CRP) and hapto... |
29,120 | Biotechnological engineering of heparin/heparan sulphate: a novel area of multi-target drug discovery. | Heparin is a sulphated glycosaminoglycan currently used as an anticoagulant and antithrombotic drug. It consists largely of 2-O-sulphated IdoA not l&r arrow N, 6-O-disulphated GlcN disaccharide units. Other disaccharides containing unsulphated IdoA or GlcA and N-sulphated or N-acetylated GlcN are also present as mi... |
29,121 | Pregnancy and delivery in protein C-deficiency. | Activated protein C (APC) is a strong inhibitor of coagulation, inactivating coagulation factors Va and VIIIa upon binding to protein S (PS) in the presence of thrombin and thrombomodulin. The normal concentration of PC in the plasma is approximately 4 microg/ml. Throughout pregnancy, PC activity and antigenic levels s... |
29,122 | The role of factor V Leiden in maternal health and the outcome of pregnancy. | There is growing evidence that women with thrombophilia are at increased risk of pregnancy related venous thromboembolism and of adverse pregnancy outcome including pregnancy loss, pre-eclampsia, intrauterine growth retardation and placental abruption. The factor V Leiden mutation is a heritable thrombophilia present i... |
29,123 | Maternal fibrinogen is necessary for embryonic development. | Fibrinogen (Fg) is a precursor of fibrin, which is one of the main components of blood clots generated during the hemostatic response. Beyond its important role in hemostasis, Fg is involving in several physiologic and pathophysiologic states, such as infection, wound healing, the progression of certain types of tumors... |
29,124 | [A case of deep vein thrombosis in spite of using an intermittent pneumatic compression device]. | A 69-year-old male patient underwent subtotal esophagectomy for esophageal cancer under sevoflurane anesthesia combined with epidural analgesia. According to the protocol for the prevention of deep vein thrombosis (DVT) in our hospital, only an intermittent pneumatic compression device (IPC) and elastic stockings were ... |
29,125 | [Anesthetic management of a patient with paroxysmal nocturnal hemoglobinuria and suspected abdominal venous thrombosis]. | A 59-year-old man with paroxysmal nocturnal hemoglobinuria (PNH) underwent an operation for lumbar disk herniation. He was given warfarin, aspirin, and steroid for PNH and suspected venous thrombosis. PNH is a hemolytic anemia due to an acquired red blood cell membrane defect at the stem cell level. The patient with PN... |
29,126 | Headache as the only neurological sign of cerebral venous thrombosis: a series of 17 cases. | Headache is the most frequent symptom in cerebral venous thrombosis (CVT), and usually the first. However, it has rarely been reported as the only symptom of CVT.</AbstractText>To study the characteristics of patients in whom headache was the only presentation of CVT in the absence of intracranial hypertension, subarac... |
29,127 | Systolodiastolic variations of blood flow during central retinal vein occlusion: exploration by dynamic angiography. | <AbstractText Label="BACKGROUND/AIM" NlmCategory="OBJECTIVE">In patients with acute central retinal vein occlusion (CRVO), dynamic angiography may reveal the presence of pulsatile flow (termed here pulsatile venular outflow, PVO) within first order veins (that is, the large veins). The main goal of this study was to in... |
29,128 | The role of ECA transection in the development of masticatory lesions in the MCAO filament model. | In the intraluminal suture model of middle cerebral artery occlusion (MCAO) in the rat, lesions of the masticator muscles associated with impaired functional outcome occur. We evaluated the role of external carotid artery (ECA) transection. We assessed whether isolated interruption of an arterial or a venous connection... |
29,129 | Cerebral venous thrombosis: influence of risk factors and imaging findings on prognosis. | To investigate imaging findings, risk factors and outcome in patients with cerebral venous thrombosis (CVT).</AbstractText>Records of all patients with diagnosis of CVT between 1992 and 2002 were reviewed. Patients with CNS infection and with CVT secondary to invasive procedures were excluded. Inherited and acquired th... |
29,130 | Improving quality of care in vascular surgery: the tools are available now. | This overview delineates the current evidence and suggested practice protocols for three areas of vascular disease evaluation and treatment that have shown particular patient benefit. Presented as brief topical reviews are (1) preoperative cardiac evaluation and risk factor modification, (2) use of autologous tissue an... |
29,131 | Computed tomographic angiography allows accurate planning of the setting and technique of open and percutaneous vascular interventions. | Vascular surgeons can offer patients with arterial and venous disorders a multitude of endovascular and surgical options. Computed tomographic angiography (CTA) has the potential to allow the development of an effective interventional strategy without subjecting patients to invasive diagnostic testing.</AbstractText>A ... |
29,132 | Short- and long-acting synthetic pentasaccharides as antithrombotic agents. | Fondaparinux sodium (Arixtra; GlaxoSmithKline) is the first of a new class of antithrombotic agents. It is a chemically synthesised pentasaccharide mimicking the site of heparin that binds to antithrombin. It is purely a factor Xa inhibitor and an inhibitor of thrombin generation that requires binding to antithrombin. ... |
29,133 | [Alternate hemodialysis catheterization access in patients with occluded peripheral venous access sites]. | The goal of this study was to evaluate translumbar and transhepatic placement of hemodialysis (HD) catheters for patients with occlusion of the veins that are commonly used for hemodialysis access.</AbstractText>Over a 12-month period three translumbar and one transhepatic hemodialysis catheters were placed in 4 patien... |
29,134 | Cerebral ischemic infarction in paroxysmal nocturnal hemoglobinuria report of 2 cases and updated review of 7 previously published patients. | Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal stem cell disorder, leading to a deficient biosynthesis of surface proteins in hematopoetic cells. Clinical symptoms consist of various combinations of intravascular hemolysis, bone marrow failure and mainly venous thrombotic events. Arterial thrombosis ha... |
29,135 | Clinical and neuroradiological spectrum of isolated cortical vein thrombosis. | Isolated cortical vein thrombosis is only rarely diagnosed, although it may commonly be overlooked.</AbstractText>We report on four patients with this diagnosis who all presented with focal sensorimotor seizures. The diagnosis was made by a typical CT and MRI-pattern, which is described in detail.</AbstractText>The pro... |
29,136 | Thrombosis during pregnancy and the postpartum period. | To describe the circumstances surrounding deep vein thrombosis among pregnant or postpartum patients enrolled in a large multicenter registry.</AbstractText>Consecutive patients with ultrasound-confirmed deep vein thrombosis were enrolled at 183 institutions during a 6-month period from October 2001 to March 2002. Fift... |
29,137 | Cerebral infarctions and brain abscess due to Lemierre syndrome. | Lemierre syndrome is characterized by anaerobic bacterial infection in the head and neck, causing thrombophlebitis of the jugular vein and septic metastasis to various distant organs, most often the lungs. Here we describe previously unreported clinical features of cerebral infarctions and brain abscess due to metastat... |
29,138 | Retrievable Günther Tulip filter complicated by sepsis and retroperitoneal hemorrhage: successful management by filter retrieval. | We encountered complications of septic shock and retroperitoneal hemorrhage which occurred after implantation of a retrievable Günther Tulip filter. A 79-year-old woman was diagnosed as right femoral vein thrombosis, and a retrievable Günther Tulip filter was deployed prior to a total knee replacement surgery... |
29,139 | A negative D-dimer assay does not rule out cerebral venous thrombosis: a series of seventy-three patients. | Cerebral venous thrombosis (CVT) is an infrequent variety of cerebrovascular disease with a wide spectrum of clinical presentations and a notoriously difficult diagnosis. Previous reports have emphasized the potential clinical utility of D-dimer assay in CVT diagnosis.</AbstractText>A rapid sensitive D-dimer assay was ... |
29,140 | Generalized changes in venous distensibility in postthrombotic patients. | In situ biomechanical properties of peripheral large veins were compared between asymptomatic young patients who had previously unilateral femoro-popliteal deep venous thrombosis (DVT) and age-matched, healthy controls; the aim of this study was to assess local or generalized alterations of venous wall biomechanics in ... |
29,141 | Subcutaneous fat accumulation and BMI associated with risk for pulmonary embolism in patients with proximal deep vein thrombosis: a population study based on 23 796 consecutive autopsies. | Although deep vein thrombosis (DVT) and pulmonary embolism (PE) are manifestations of the same disease, far from all patients develop PE. Our objective was to investigate risk-modifying factors. SETTING, SUBJECTS AND DESIGN: Between 1970 and 1982, 23,796 autopsies, representing 84% of all in-hospital deaths in the Malm... |
29,142 | The Paget-Schroetter syndrome. | Primary axillo-subclavian venous thrombosis is pathology of the young working man. It affects above all the main upper limb and arises during a physical activity of the shoulder. Its aetiology is complex and multifactorial. It is most often the consequence of a chronic compression of the subclavian vein at the level of... |
29,143 | A randomized, controlled trial of a new vascular catheter flush solution (minocycline-EDTA) in temporary hemodialysis access. | We previously demonstrated that minocycline-EDTA was efficacious at preventing catheter-related bloodstream infections (BSIs) in three patients with recurrent infections. This study compared heparin with minocycline-EDTA as flush solutions used among dialysis patients with central venous catheters, a high-risk group fo... |
29,144 | [Modern approach to treatment in pulmonary thromboembolism]. | Pulmonary embolism (PE) and deep vein thrombosis (DVT), respectively venous thromboembolism (VIE), are relatively frequent diseases. Appropriate management of PE includes risk stratification, preventive and primary therapy. Appearance of the disease ranges from mild to severe, and rapid and accurate risk stratification... |
29,145 | Pulmonary embolism aggravated by two short flights 3 days apart. | An elderly internist experienced aggravation of preexisting pulmonary emboli following each of two short flights of 75 min apiece 3 d apart. A brief discussion of risk factors is included. It is suggested that pertinent reports should separate venous thromboembolic disease (VTE) from uncomplicated deep venous thrombosi... |
29,146 | Tests of trait-haplotype association when linkage phase is ambiguous, appropriate for matched case-control and cohort studies with competing risks. | The impact of competing risks on tests of association between disease and haplotypes has been largely ignored. We consider situations in which linkage phase is ambiguous and show that tests for disease-haplotype association can lead to rejection of the null hypothesis, even when true, with more than the nominal 5 per c... |
29,147 | Deviations of placement/function of permanent central vein catheters for hemodialysis. | Fourteen cases of malposition of a permanent central vein catheter for hemodialysis or poor blood flow associated with thrombosed central veins but correct catheter positioning, in 13 patients suffering from end stage renal disease, presented from September 1991 to December 2003 among 385 permanent central vein cathete... |
29,148 | An interesting cause of pulmonary emboli: acute carbon monoxide poisoning. | Carbon monoxide poisoning, a public health problem of considerable significance, is a relatively frequent event today, resulting in thousands of hospitalizations annually. A 70-year-old lady was seen in the emergency department with a provisional diagnosis of carbon monoxide poisoning. The previous night, she slept in ... |
29,149 | Factor V Leiden mutation in cerebrovascular disease. | Several studies indicate a high prevalence of factor V Leiden mutation as the most frequent coagulation defect found in patients with venous thrombosis. The relationship between this mutation and cerebrovascular disease has not been established in adults. In this investigation, we studied 29 patients with ischemic stro... |
29,150 | Efficiency of systematic thrombophilia screening in idiopathic venous thrombosis: a prospective study in internal medicine. | In case of unprovoked venous thromboembolism (VTE), the screening of thrombophilia is recommended whatever the age of the patient and the type of risk factors (RF). This prospective study was conducted in patients with unprovoked VTE to detect some predictive factors to have a higher risk of thrombophilia, focusing on ... |
29,151 | Identification of thrombin antibodies in patients with antiphospholipid syndrome. | Venous or arterial thrombosis, abortion, and the presence of antiphospholipid antibodies (aPL) define the criteria for the antiphospholipid syndrome (APS). A heterogeneous group of antibodies against phospholipids and plasma proteins may influence several coagulation pathways and lead to thrombophilia. We investigated ... |
29,152 | The effect of oral anticoagulation on clotting during hemodialysis. | Between 5% and 10% of hemodialysis patients are treated with oral anticoagulants. It is currently unknown whether additional anticoagulation with heparin or low-molecular-weight heparin (LMWH) is needed to prevent clotting during hemodialysis.</AbstractText>In this prospective, randomized, cross-over study 10 patients ... |
29,153 | The pharmacogenetics of coumarin therapy. | Vitamin K antagonists (coumarins) are widely-used oral anticoagulants for the prevention of venous thromboembolism and strokes. Wide inter-individual variation in dose response and frequent bleeds characterize the initiation of coumarin therapy. Over the past 10 years both genetic and nongenetic determinants of coumari... |
29,154 | [The use of the Export Catheter device in a patient with acute myocardial infarction for thrombotic occlusion of the venous graft on the left anterior descending coronary artery: a case report]. | Coronary angioplasty, eventually followed by stent implantation, represents the gold standard of acute myocardial infarction (AMI) treatment. Optimal reperfusion implies both patency of the infarct-related artery and a good myocardial microrevascularization with normal tissue reperfusion. The so called no-reflow phenom... |
29,155 | Critically ill obstetric patients in an American and an Indian public hospital: comparison of case-mix, organ dysfunction, intensive care requirements, and outcomes. | To compare case-mix, health care practices, and outcome in obstetric ICU admissions in inner-city teaching hospitals in economically developed and developing countries.</AbstractText>Retrospective study.</AbstractText>Ben Taub General Hospital (BTGH), Houston, Texas, and King Edward Memorial Hospital (KEMH), Mumbai, In... |
29,156 | Phase II study of weekly oxaliplatin plus infusional fluorouracil and folinic acid (FUFOX regimen) as first-line treatment in metastatic gastric cancer. | Oxaliplatin plus fluorouracil/folinic acid (5-FU/FA) every 2 weeks has shown promising activity in advanced gastric cancer. This study assessed the efficacy and safety of weekly oxaliplatin plus 5-FU/FA (FUFOX regimen) in the metastatic setting. Patients with previously untreated metastatic gastric cancer received oxal... |
29,157 | Vein wall remodeling after deep vein thrombosis involves matrix metalloproteinases and late fibrosis in a mouse model. | Deep venous thrombosis (DVT) confers vein wall injury associated with fibrosis and extracellular matrix (ECM) turnover, likely mediated by matrix proteases. This study investigated the expression of proteases and collagen involved in early vein wall remodeling.</AbstractText>In the mouse, DVT was produced by ligation o... |
29,158 | Results of limb-sparing surgery with vascular replacement for soft tissue sarcoma in the lower extremity. | To evaluate limb-salvage surgery with vascular resection for lower extremity soft tissue sarcomas (STS) in adult patients and to classify blood vessel involvement.</AbstractText>Subjects were consecutive patients (median age, 56 years) who underwent vascular replacement during surgery of STS in the lower limb between J... |
29,159 | The safety of fondaparinux for the prevention and treatment of venous thromboembolism. | Fondaparinux is the first synthetic selective Factor Xa inhibitor. Along with its antithrombotic efficacy, the safety of fondaparinux has been documented in several Phase II and III clinical trials, including the prevention of venous thromboembolism in patients undergoing major orthopaedic surgery or high-risk abdomina... |
29,160 | Gunther tulip inferior vena cava filter placement during treatment for deep venous thrombosis of the lower extremity. | To evaluate the efficacy and safety of Gunther tulip retrievable vena cava filter (GTF) implantation to prevent pulmonary embolism during intravenously administered thrombolytic and anticoagulation therapy and interventional radiological therapy for occlusive or nonocclusive deep venous thrombosis (DVT) of the lower ex... |
29,161 | Spontaneous migration of a Port-a-Cath catheter into ipsilateral jugular vein in two patients with severe cough. | Port-A-Cath systems are widely used for long-term therapy in the treatment of malignancies and infection. Spontaneous migration of Port-A-Cath catheters after satisfactory initial placement is uncommon but is associated with a number of complications, including neck pain, shoulder pain, ear pain, infection, venous thro... |
29,162 | Long-term follow-up in 128 patients with primary antiphospholipid syndrome: do they develop lupus? | We retrospectively studied a large cohort of patients with primary antiphospholipid syndrome (APS) from 4 different referral centers to analyze the clinical and serologic features and, specifically, to determine the number of patients going on to develop systemic lupus erythematosus (SLE) or other autoimmune disease af... |
29,163 | Antithrombotic therapy practices in US hospitals in an era of practice guidelines. | Antithrombotic therapy is efficacious for the prevention of thromboembolic disease, but it necessitates careful risk-benefit assessment.</AbstractText>Antithrombotic therapy data were retrospectively collected from inpatient medical records at 38 US hospitals. Patients treated for atrial fibrillation, acute myocardial ... |
29,164 | Eight-year follow-up of patients with permanent vena cava filters in the prevention of pulmonary embolism: the PREPIC (Prevention du Risque d'Embolie Pulmonaire par Interruption Cave) randomized study. | In a randomized trial in patients with proximal deep-vein thrombosis, permanent vena cava filters reduced the incidence of pulmonary embolism but increased that of deep-vein thrombosis at 2 years. An 8-year follow-up was performed to assess their very long-term effect.</AbstractText>Four hundred patients with proximal ... |
29,165 | Definition of the post-thrombotic syndrome, differences between existing classifications. | Accepted diagnostic criteria exist for the diagnosis of deep vein thrombosis (DVT). However, no uniform definition for the diagnosis and treatment of the post-thrombotic syndrome (PTS) exists. We examined the various definitions of PTS that are used and their relationships with invasive venous pressure measurement.</Ab... |
29,166 | [Prevention of venous thromboembolism following cardiac, vascular or thoracic surgery]. | In the absence of thromboprophylaxis, coronary artery bypass graft surgery (CABG), intrathoracic surgery (thoracotomy or video-assisted thoracoscopy), abdominal aortic surgery and infrainguinal vascular surgery are high-risk surgeries for the development of venous thromboembolic events (VTE). The incidence of VTE follo... |
29,167 | Difficulties in performing clinical trials of antithrombotic therapy in neonates and children. | The practice of evidence-based medicine is based on the results of properly designed, conducted and analyzed studies. Evidence for the safety and efficacy of therapies is established through clinical trials. However, there are a number of difficulties in the design and management of clinical trials in children. We expl... |
29,168 | Permanent transfemoral pacemaker: a single-center series performed with an easier and safer surgical technique. | When venous access via the upper venous tree is not possible, the usual approach is to proceed to epicardial lead placement.</AbstractText>This report presents a consecutive series of 12 permanent pacemaker systems utilizing the right femoral vein for venous access implanted between May 2001 and October 2004.</Abstract... |
29,169 | High incidence of recurrence and hematologic events following liver transplantation for Budd-Chiari syndrome. | Most cases of Budd-Chiari syndrome (BCS) in Western countries are related to underlying hematologic diseases with inherent thrombogenic propensity. We evaluated the long-term outcome, risks for recurrent disease, and other hematologic complications following orthotopic liver transplantation (OLT) for BCS.</AbstractText... |
29,170 | [Congenital complete atrio-ventricular block]. | Congenital complete atrio-ventricular block is a rare condition, the result of an anatomical anomaly of the conduction pathways, or even the trans-placental passage of maternal antibodies causing fetal myocarditis with fibrosis of the conduction tissue. It is not clear whether AV block discovered later in childhood is ... |
29,171 | Conservative management of epistaxis: are we putting patients at risk of developing venous thromboembolic complications? | A retrospective study of 1585 patients, admitted with epistaxis to a busy District General Hospital in the United Kingdom between 1990 and 2000, was undertaken in order to identify the relationship between hospital admission for epistaxis and the development of a venous thromboembolic event. Only one person (0.06%) dev... |
29,172 | Clinical and molecular characterization of the first adult congenital disorder of glycosylation (CDG) type Ic patient. | Congenital disorder of glycosylation (CDG) type Ic, the second largest subtype of CDG, is caused by mutations in human ALG6 (hALG6). This gene encodes the alpha1,3-glucosyltransferase that catalyzes transfer of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. In this r... |
29,173 | Transdermal estradiol therapy for prostate cancer reduces thrombophilic activation and protects against thromboembolism. | Oral estrogens were an effective treatment for prostate cancer but were abandoned because of an increased risk of cardiovascular toxicity and particularly thromboembolism. We have recently shown that transdermal estradiol produces an effective tumor response and negligible cardiovascular toxicity. Here we report the in... |
29,174 | [Prevention of venous perioperative thromboembolism in ENT and maxillofacial surgery]. | There are few studies of poor methodological quality on the risk of thromboembolism in head and neck surgery. The incidence of symptomatic deep vein thrombosis is estimated between, 0.1% and 0.6%. The patient's risk factors (cancer, alcoholism, smoking, malnutrition) determine for the assessment of the potential benefi... |
29,175 | [Thromboprophylaxis in elective spinal surgery and spinal cord injury]. | The risk of deep vein thrombosis (DVT) after spinal cord injury is very high. Without prophylaxis the incidence of DVT using venography is 81% and the risk of symptomatic DVT is between 12 and 23%. The risk is much lower in elective spine surgery. After discectomy or laminectomy on less than two spine levels, the risk ... |
29,176 | [Thromboprophylaxis in neurosurgery and head trauma]. | The incidence of deep vein thrombosis (DVT) is between 20 and 35% using contrast venography, with a rate of symptomatic DVT between 2.3 and 6% in neurosurgery without any prophylaxis. The risk of DVT is poorly evaluated in head injured patients but is around 5%. Specific risk factors in neurosurgery are: a motor defici... |
29,177 | Effects of short-term glucocorticoids on hemostatic factors in healthy volunteers. | Increased circulating levels of hemostatic factors have been associated with arterial and venous thrombosis. Although in vitro evidence suggests that glucocorticoids may activate hemostasis and inhibit thrombolysis, no controlled in vivo studies have examined the effects of glucocorticoids on hemostatic factors. We hyp... |
29,178 | Migration of two venous stents into the right ventricle in a patient with May-Thurner syndrome. | May-Thurner syndrome is an uncommon process in which the right common iliac artery compresses the left common iliac vein, possibly resulting in pain, severe edema of the left leg or in left iliofemoral deep vein thrombosis [May R, Thurner J. The cause of the predominately sinistral occurrence of thrombosis of the pelvi... |
29,179 | Mondor's disease of the penis following a long-haul flight. | Mondor's disease of the penis, otherwise known as superficial thrombophlebitis (STP) or thrombosis of the dorsal vein, is an under-reported benign condition, the aetiology of which is poorly understood. It is characterized by a sudden, indurated swelling of the vein, often occurring after vigorous sexual activity. We r... |
29,180 | Deep venous thrombosis in medical-surgical critically ill patients: prevalence, incidence, and risk factors. | Critically ill patients may be at high risk of venous thromboembolism. The objective was to determine the prevalence, incidence, and risk factors for proximal lower extremity deep venous thrombosis among critically ill medical-surgical patients.</AbstractText>Prospective cohort.</AbstractText>Closed university-affiliat... |
29,181 | Percutaneous transluminal mitral valvuloplasty reduces circulating soluble CD40 ligand in rheumatic mitral stenosis. | Recent data suggest that the pathogenesis of vascular inflammation and thrombosis involves CD40 ligand (CD40L), which is mostly derived from platelets. Previous studies have demonstrated that platelet activation occurs in peripheral blood of patients with rheumatic mitral stenosis (MS). However, in patients with MS, th... |
29,182 | Causes and predictors of death in cerebral venous thrombosis. | The causes of death of patients with cerebral venous thrombosis (CVT) have not been systematically addressed in previous studies. We aimed to analyze the causes and predictors of death during the acute phase of CVT in the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) to identify preventable or... |
29,183 | The post-thrombotic syndrome after upper extremity deep venous thrombosis in adults: a systematic review. | Post-thrombotic syndrome is a chronic, potentially debilitating complication of deep vein thrombosis (DVT) of the lower extremity. Comparatively little is known about post-thrombotic syndrome after upper extremity DVT (UEDVT).</AbstractText>To perform a systematic review of clinical studies that have examined the incid... |
29,184 | Retinal vascular disease in hypertension. Risk factor modification optimizes vision outcomes. | In a previous article (July 2004, page 57), Dr Colucciello reviewed nonproliferative and proliferative diabetic retinopathy. In this article, he discusses retinal vascular disease associated with hypertension, which is especially likely to occur in persons with vasculopathic risk factors. Retinal vein occlusion, retina... |
29,185 | Alcoholic chronic pancreatitis with simultaneous multiple severe complications--extrahepatic portal obliteration, obstructive jaundice and duodenal stricture. | The major complications of chronic pancreatitis are malabsorption, diabetes mellitus, pancreatic calcification and pseudocysts. Sinistral portal hypertension due to splenic vein thrombosis, obstructive jaundice and duodenal stricture have also been reported as complications of chronic pancreatitis. However, a case havi... |
29,186 | Band ligation plus sclerotherapy versus sclerotherapy alone in children with extrahepatic portal venous obstruction. | Although endoscopic band ligation (EVL) plus sclerotherapy (EST) has shown to be superior to any individual method, there is no study in children. We therefore analyzed our experience of EST and EVL + EST in children with extrahepatic portal venous obstruction (EHPVO). Over a period of 8 years, 136 children who present... |
29,187 | Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia. | We conducted a randomized comparison of hydroxyurea with anagrelide in the treatment of essential thrombocythemia.</AbstractText>A total of 809 patients with essential thrombocythemia who were at high risk for vascular events received low-dose aspirin plus either anagrelide or hydroxyurea. The composite primary end poi... |
29,188 | Successful therapy with argatroban for superior mesenteric vein thrombosis in a patient with congenital antithrombin deficiency. | A 38-year-old woman was admitted with superior mesenteric vein (SMV) thrombosis, which was refractory to anticoagulation therapy. The plasma antithrombin activity was decreased and hardly compensated by concentrated antithrombin preparation due to high consumption rate. However, successful anticoagulation was achieved ... |
29,189 | Evidence-based clinical improvement for mechanically ventilated patients. | Bundling or grouping together evidence-based interventions to improve care for the mechanically ventilated patient was piloted by a 10-bed medical-surgical critical care unit of a hospital. The bundled care interventions included: (a) keeping the head of bed elevated at 30 degrees, (b) instituting daily interruption of... |
29,190 | [Renal transplantation techniques in children with impaired patency of the inferior vena cava or iliac vein]. | Congenital or acquired disorders of patency of the inferior vena cava (IVC) or iliac veins have been considered for a long time to be an almost insurmountable technical obstacle in paediatric renal transplantation. The authors report their experience based on 7 transplantations performed in children with a disorder of ... |
29,191 | Comparisons of outcomes and survivals for two central venous access port systems. | This study compares the outcomes and survivals between two central venous access port systems.</AbstractText>Medical records from 298 cancer patients who had received open-end (Deltec, N = 159) or closed-end (Groshong, N = 139) port catheter insertions were retrospectively reviewed.</AbstractText>The infection, thrombo... |
29,192 | [Idiopathic hypertrophic cranial pachymeningitis diagnosed after venous thrombosis]. | Idiopathic hypertrophic cranial pachymeningitis (IHCP) is a rare and little known form of chronic inflammation of the dura mater, the pathogenesis of which remains unclear.</AbstractText>We report the case of a 77-year-old male who was admitted to hospital after suffering a stroke; following the findings in the MR imag... |
29,193 | Should I report the death to the Coroner? | The aim of this article is to outline the circumstances in which a general practitioner should report a patient's death to the Coroner. |
29,194 | Pulmonary embolism--assessment and management. | Pulmonary embolism (PE) is a potentially life threatening disorder most commonly seen in debilitated patients with other common medical problems.</AbstractText>This article aims to increase the reader's understanding of the aetiology and pathophysiology of PE so as to identify particular at risk patients. An approach t... |
29,195 | Ximelagatran: an orally active direct thrombin inhibitor. | The chemistry, pharmacology, pharmacokinetics, clinical efficacy, dosage and administration, contraindications, and adverse effects of ximelagatran are reviewed.</AbstractText>Ximelagatran is the first orally active direct thrombin inhibitor to be tested in Phase III clinical trials. After oral administration, ximelaga... |
29,196 | [The treatment of venous coronary grafts disease]. | Since the introduction of venous coronary bypass grafting in 1968, venous graft disease remains a major therapeutic challenge. The alternative to surgical reintervention is saphenous vein graft angioplasty with the combination of distal protection and drug eluting stents, available since 2002. Although randomised contr... |
29,197 | Mapping changes in surgical mortality over 9 years by peer review audit. | There is increasing public scrutiny of deaths among surgical patients. This analysis sought evidence of changes in practice over time in the management of patients who died under surgical care.</AbstractText>The surgeons and anaesthetists in National Health Service hospitals providing the care of all surgical patients ... |
29,198 | Traveler's thrombosis: a systematic review. | Anecdotal evidence suggests a possible link between travel and venous thromboembolism (VTE). We systematically evaluated the evidence from observational studies.</AbstractText>We searched studies evaluating the risk of venous thrombosis in relation to traveling from MEDLINE and EMBASE up tp March 2004, together with a ... |
29,199 | [Fetal nephro-/uropathy: a retrospective analysis of 124 cases seen in the period from 1996 to 2002]. | The embryological development of the kidneys and the urinary tract follows a complex choreography. Disorders are quite common. The incidence of disorders amounts to 0.3 - 0.8 % of live-born infants. In addition, several chromosomal anomalies are combined with renal malformations. The poor prognosis of some of these dis... |
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