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29,300 | Management of pregnant women with increased risk of venous thrombosis. | To evaluate the usefulness of score based management of pregnancies with high risk of venous thromboembolism (VTE).</AbstractText>116 consecutive pregnancies in 109 women with confirmed thrombophilia and/or history of VTE were studied. Patients were managed in accordance with international recommendations. Recently, a ... |
29,301 | [Mondor's disease: a complication after breast surgery]. | Mondor's disease is a rare but not uncommon complication of breast surgery. This problem is commonly described as the thrombophlebitis of the superficial thoracoabdominal veins. Symptoms combine painful contracture occurring in the sub-mammary region and/or in the axillary region, rising during arm abduction. The contr... |
29,302 | Travel and thrombosis. | The available evidence suggests an association between long distance travel and the development of venous thromboembolism. The main problem for travellers and physicians is the interpretation of the evidence and its translation into appropriate advice on the risk and the prevention of thrombosis. Most available data re... |
29,303 | Hyperhomocysteinaemia as a risk factor for deep-vein thrombosis. | Several studies have shown a relation between hyperhomocysteinaemia and vascular disease. To assess the risk of deep-vein thrombosis (DVT) associated with hyperhomocysteinaemia, we studied plasma homocysteine levels in patients with deep-vein thrombosis and in normal control subjects.</AbstractText>We measured plasma h... |
29,304 | Anticardiolipin antibody and Taiwanese chronic haemodialysis patients with recurrent vascular access thrombosis. | Vascular access failure is a major cause of morbidity in chronic haemodialysis (HD) patients. However, some factors (such as homocysteine levels) are known regarding the risk factors predisposing certain HD patients to vascular access thrombosis (VAT). Immunoglobulin-G anticardiolipin antibody (IgG-ACA) is strongly ass... |
29,305 | Deep vein thrombosis and pulmonary embolism reported in the Prescription Event Monitoring Study of Yasmin. | To evaluate cases of deep vein thrombosis (DVT) and pulmonary embolism (PE) reported in a prescription event monitoring study of Yasmin, an oral contraceptive.</AbstractText>Reports of DVT/PE and events suggestive of DVT/PE were followed up by questionnaire.</AbstractText>Thirteen cases (DVT five; PE eight), each with ... |
29,306 | [Anagrelide in the treatment of thrombocythemia essential (ET)]. | Essential thrombocythaemia (ET), the most often occurring myeloproliferative disorder is a clonal malignant disorder arising from stem cell. The course of the disease is complicated by some severe thrombotic events and far less commonly by haemorrhagic phenomena. Treatment of ET consist of antiplatelet drugs (e.g. aspi... |
29,307 | Protein C and/or S deficiency presenting as peripheral arterial insufficiency. | Although protein C and/or S deficiency has frequently been associated with venous thromboembolic events, instances of arterial thromboses have been reported. However, the exact incidence of protein C and/or S deficiency in patients with peripheral arterial insufficiency has not been established. Furthermore, given the ... |
29,308 | Incidence of upper limb venous thrombosis associated with peripherally inserted central catheters (PICC). | The objective of this study was to prospectively determine the incidence of venous thrombosis (VT) in the upper limbs in patients with peripherally inserted central catheters (PICC). We prospectively investigated the incidence of VT in the upper limbs of 26 patients who had PICC inserted. The inclusion criteria were al... |
29,309 | An underestimated combination of opposites resulting in enhanced thrombotic tendency. | Heterozygous carriers of factor V (FV) Leiden who also carry FV deficiency often develop venous thromboembolism, but the thrombosis risk associated with this rare condition (pseudohomozygous activated protein C resistance) is still unclear. The thrombosis risk of genetically characterized pseudohomozygotes (n = 6) was ... |
29,310 | [Prospective study of the risk factors for the development of post-thrombotic syndrome after proximal deep venous thrombosis]. | The incidence and risk factors for the development of post-thrombotic syndrome (PTS) are not well known, so the aim of our study is to evaluate the development of PTS after proximal deep vein thrombosis (DVT) and its relationship with several clinical, laboratory and therapeutic factors.</AbstractText>Prospective, obse... |
29,311 | The surgical treatment of ilio-femoral venous obstruction. | A series of 9 patients of a mean age of 48 years, operated on for compression of the ilio-femoral venous axis is reported. The cause of obstruction was external compression in 3 cases, a retroperitoneal sarcoma in 1 case, and an infrarenal aortic aneurysm in 2. Two patients presented with a Cockett's syndrome, 3 with a... |
29,312 | Using a bundle approach to improve ventilator care processes and reduce ventilator-associated pneumonia. | A "bundle" of ventilator care processes (peptic ulcer disease prophylaxis, deep vein thrombosis prophylaxis, elevation of the head of the bed, and a sedation vacation), which may also reduce ventilator-associated pneumonia (VAP) rates, can serve as a focus for improvement strategies in intensive care units (ICUs). Betw... |
29,313 | Prevention of catheter-related bloodstream infections: an appraisal of developments in designing an infection-resistant 'dream dialysis-catheter'. | With the increasing number of elderly, diabetics and debilitated patients being accepted for haemodialysis (HD), the use of central venous catheters (CVCs) as vascular access has become more widespread, with an inevitable inherent risk of catheter-related bloodstream infections (CRBSI) and ensuing mortality. No reliabl... |
29,314 | [Minimally invasive surgery of acute superficial varicothrombophlebitis in patients having somatic contraindication to venectomy]. | An analysis was made of complex examination and the following treatment of 21 patients with acute superficial varicothrombophlebitis who had some pronounced pathology of internal organs preventing radical treatment. An original technology of treatment of varicothrombophlebitis developed by the authors includes crossect... |
29,315 | Long-term results of pars plana vitrectomy combined with filtering surgery for neovascular glaucoma. | To analyze the effectiveness of vitrectomy combined with filtering surgery for neovascular glaucoma.</AbstractText>Twenty-one eyes with neovascular glaucoma underwent pars plana vitrectomy combined with filtering surgery between January 1995 and December 2003. Thirteen eyes (10 cases) had neovascular glaucoma secondary... |
29,316 | Transient hepatic attenuation differences at biphasic spiral CT examinations. | Transient hepatic attenuation difference (THAD) is a perfusion disorder that can sometimes be observed in hepatic arterial phase of a biphasic spiral CT examination. The involved site of liver by THAD appears as an area of high attenuation on the hepatic arterial phase image and returns to normal attenuation on portal ... |
29,317 | CTC-11 (Teijin). | Teijin and Chemo-Sero are codeveloping CTC-111 as a treatment for disseminated intravascular coagulation (DIC) due to protein C deficiency. The drug was launched for the treatment of protein C deficiency in Japan on January 31, 2001 and as of October 2001 was awaiting approval for the treatment of DIC, also in Japan [4... |
29,318 | Thrombus formation induced by antibodies to beta2-glycoprotein I is complement dependent and requires a priming factor. | We monitored the number of intravascular platelet-leukocyte aggregates (PLAs) and thrombotic occlusions (TOs) by intravascular microscopy in the mesentery of rats receiving antiphospholipid (aPL) immunoglobulin G (IgG) purified from the sera of patients with antiphospholipid syndrome. aPL IgG had no procoagulant effect... |
29,319 | Tinzaparin in outpatients with pulmonary embolism or deep vein thrombosis. | The low-molecular-weight heparins (LMWHs) have been shown to be effective in the outpatient treatment of deep vein thrombosis (DVT). Data regarding outpatient use of any LMWH in pulmonary embolism (PE) or tinzaparin in DVT while transitioning therapy to a vitamin K antagonist are limited.</AbstractText>To determine the... |
29,320 | Trial to evaluate the management of paroxysmal supraventricular tachycardia during an electrophysiology study with tecadenoson. | Tecadenoson is a potent selective A1-adenosine receptor agonist with a dose-dependent negative dromotropic effect on the AV node. Tecadenoson terminates induced paroxysmal supraventricular tachycardia (PSVT) without the clinically significant side effects caused by stimulation of other adenosine receptors. This trial w... |
29,321 | Treatment of hepatic venous outflow obstruction after piggyback liver transplantation. | To evaluate retrospectively the endovascular management of hepatic venous outflow obstruction after piggyback orthotopic liver transplantation.</AbstractText>The study was performed with the approval and under the guidelines of the institutional review board and complied with the Health Insurance Portability and Accoun... |
29,322 | Variation in the diagnostic performance of D-dimer for suspected deep vein thrombosis. | Numerous studies have evaluated the accuracy of D-dimer in diagnosing suspected deep vein thrombosis (DVT), but results are conflicting.</AbstractText>To overview estimates of the diagnostic accuracy of D-dimer and identify causes of variation.</AbstractText>Systematic review, meta-analysis and meta-regression.</Abstra... |
29,323 | Removal of vena caval filter at 224 days. | Patients at risk of pulmonary embolism usually receive anticoagulants, which are contraindicated in trauma victims. A woman with extensive deep venous thrombosis after a vehicle accident had a nitinol Recovery Filter inserted prophylactically. After her recovery, she requested filter removal because of her intention to... |
29,324 | Pressure ulcer prevalence in people with spinal cord injury: age-period-duration effects. | To examine age-period-duration patterns of the prevalence of pressure ulcers in community-residing people with spinal cord injury (SCI).</AbstractText>Multicenter cohort study.</AbstractText>Nine Model Spinal Cord Injury Systems throughout the United States.</AbstractText>People with SCI (N=3361) injured between 1986 a... |
29,325 | Intravitreal versus retrobulbar injections of triamcinolone for macular edema associated with branch retinal vein occlusion. | To compare the short-term effect of intravitreal versus retrobulbar injection of triamcinolone acetonide for the treatment of macular edema caused by branch retinal vein occlusion.</AbstractText>Randomized clinical trial.</AbstractText>Sixty eyes of 60 patients who had macular edema associated with branch retinal vein ... |
29,326 | Incidence of thrombotic complications in patients with haematological malignancies with central venous catheters: a prospective multicentre study. | This prospective, observational and multicentre study assessed the incidence of, and risk factors for, symptomatic venous thrombotic complications after central venous catheter (CVC) positioning in patients with haematological malignancies. A total of 458 consecutive CVC insertions were registered in 416 patients (81.2... |
29,327 | Solution structure of the Ca2+-Binding EGF3-4 pair from vitamin K-dependent protein S: identification of an unusual fold in EGF3. | Vitamin K-dependent protein S is a cofactor of activated protein C, a serine protease that regulates blood coagulation. Deficiency of protein S can cause venous thrombosis. Protein S has four EGF domains in tandem; domains 2-4 bind calcium with high affinity whereas domains 1-2 mediate interaction with activated protei... |
29,328 | Superficial vein thrombosis and hypercoagulable states: the evidence. | To assess the demographic features of superficial vein thrombosis and its relation with the occurrence of hypercoagulable states.</AbstractText>Data were gathered from pertinent papers using a MEDLINE search and an exhaustive bibliography review. Studies were considered only when they contained material to superficial ... |
29,329 | [Primary antiphospholipid syndrome and cerebrovascular disturbances]. | Neurological, including cecbrovascular, disorders frequently emerge in primary antiphospholipid syndrome (PAS). Clinical peculiarities of PAS were studied in 113 patients with cerebrovascular disturbances. Its had mainly ischemic patogenesis. Structure of cerebrovascular disorders was as follows: stroke (33% cases), tr... |
29,330 | Treatment of postoperative bleeding after fondaparinux with rFVIIa and tranexamic acid. | Treatment of a haemorrhagic shock after just a single dose of fondaparinux in an orthopaedic patient with reduced renal clearance is presented. Since all routine haemostatic parameters were nearly normal, single doses of rFVIIa (90 microg/kg) and of tranexamic acid (15 mg/kg) were administered to improve thrombin gener... |
29,331 | Warfarin dose related to apolipoprotein E (APOE) genotype. | Warfarin is an anticoagulant which acts through interference with the recycling of vitamin K in the liver, leading to reduced activation of several clotting factors. Apolipoprotein E plays a central role in the uptake of the lipid-soluble vitamin K. The apolipoprotein E (APOE) alleles E2, E3 and E4 encode the three maj... |
29,332 | An animal model for venous thrombosis and spontaneous pulmonary embolism. | An animal model.</AbstractText>To test the natural sequence of venous thrombosis and pulmonary thromboembolism experimentally.</AbstractText>Veterans Administration Hospital, USA.</AbstractText>In dogs, a venous thrombosis was induced in a isolated segment of the internal jugular vein by a 5 min exposure to sodium morr... |
29,333 | Nodular regenerative hyperplasia, portal vein thrombosis, and avascular hip necrosis due to hyperhomocysteinaemia. | A male patient with portal hypertension, portal vein thrombosis, spontaneous splenorenal shunt formation, and encephalopathy, thought to have post-hepatitis B cirrhosis, is described. His condition deteriorated and necessitated liver transplantation. In the explant liver, nodular regenerative hyperplasia with pronounce... |
29,334 | Epidural analgesia improves early rehabilitation after total knee replacement. | To compare epidural anesthesia and analgesia with spinal anesthesia with intravenous morphine analgesia for its effect on range of motion (ROM) and early rehabilitation after total knee replacement.</AbstractText>Randomized prospective study.</AbstractText>Tertiary care, academic medical center.</AbstractText>Thirty-ei... |
29,335 | Trends in the incidence of pulmonary embolism and deep venous thrombosis in hospitalized patients. | Trends in the incidences of pulmonary embolism (PE), deep venous thrombosis (DVT), and venous thromboembolism (VTE) (PE or DVT, or both) in hospitalized adults (aged > or =20 years) were evaluated using data from the National Hospital Discharge Survey. From 1979 to 1999, the incidence of DVT in hospitalized patients... |
29,336 | Risk of venous thromboembolic disease in women A qualitative systematic review. | To review the scientific evidence on the risk and prevention of venous thromboembolic disease (VTD) associated with specific clinical factors in women.</AbstractText>Qualitative systematic review.</AbstractText>MEDLINE, Cochrane library, clinical practice guidelines, and referenced articles from these sources.</Abstrac... |
29,337 | Colour Doppler ultrasound assessment of well-functioning mature arteriovenous fistulas for haemodialysis access. | A well-functioning mature arteriovenous fistula is essential for the maintenance of haemodialysis in patients with chronic renal failure. The Brescia-Cimino arteriovenous fistula has the best survival characteristics and low rate of complications. The most common reason of fistula failure is thrombosis caused by stenos... |
29,338 | The antiphospholipid antibody syndrome research in patients with retinal venous occlusion. | The antiphospholipid antibody syndrome (APAS) is a condition associated with abnormal thrombosis and the presence of anticardiolipin antibodies (aCL).</AbstractText>Thirty-two patients (20 male and 12 female) aged between 29 and 75 years (mean +/- SD: 56.4 +/- 12.34) with retinal venous occlusive disease were studied. ... |
29,339 | Implementation of outpatient treatment of deep-vein thrombosis in private practices in Germany. | Implementation of outpatient treatment (OT) of deep-vein thrombosis (DVT) is slow despite clear evidence that it is effective, safe and cost-efficient.</AbstractText>An initiative was launched with the help of the Professional Association of Phlebologists of Germany and the industry to familiarize physicians in private... |
29,340 | Genetically-induced deep venous thrombosis presenting as acute mastoiditis. | Sigmoid sinus thrombosis (SST) usually follows acute as well as chronic otitis media with coalescent mastoiditis. A singular case of noncoalescent mastoiditis complicated with thrombosis of deep cerebral sinuses occurring in a young child is presented. A genetic thrombophilic disorder (prothrombin G20210A allele mutati... |
29,341 | Successful management of inferior vena cava thrombus complicating advanced germ cell testicular tumor with temporary inferior vena cava filter. | We report a case of right testicular tumor with inferior vena cava (IVC) thrombus. Due to the risk of pulmonary embolization, a temporary IVC filter had been inserted during chemotherapy. There were no complications with the temporary IVC filter during the implantation period. The patient was safely treated with system... |
29,342 | Femoral neck fractures. | Despite the tremendous advances in the science and practice of orthopaedic surgery, anesthesia, and perioperative care, repair of displaced fractures of the neck of the femur is still associated with complications in up to one third of patients. The risk of nonunion and osteonecrosis in particular is virtually the same... |
29,343 | Nonsurgical and surgical management of lumbar spinal stenosis. | The symptoms associated with lumbar spinal stenosis can decrease quality of life and may cause patients to seek treatment. Except in rare cases of rapid neurologic progression or cauda equina syndrome, nonsurgical modalities should be the initial treatment choice. Activity modification, a variety of medications, epidur... |
29,344 | Blood management in total joint arthroplasty. | One of the primary goals in the perioperative care of orthopaedic patients undergoing surgery is the avoidance of allogeneic transfusion. There are a number of ways to lessen blood loss during surgical intervention including regional hypotensive anesthesia, careful and atraumatic surgical technique, and coagulation of ... |
29,345 | Hypereosinophilia with systemic thrombophlebitis. | A 34-year-old Japanese woman developed subcutaneous induration in the left thigh, then showed extreme eosinophilia, and died of hemorrhagic infarction of the brain. Autopsy revealed endocarditis with eosinophil infiltration and systemic thrombophlebitis, including pulmonary veins and intrahepatic branches of the portal... |
29,346 | Causes of portal venous thrombosis in cirrhotic patients: the role of genetic and acquired factors. | We compared frequencies of three common prothrombotic mutations (factor V Leiden, the G20210A mutation of the prothrombin gene, and homozygosity for C677T methylenetetrahydrofolate reductase) in 219 cirrhotic patients, 43 with and 176 without portal vein thrombosis (PVT). The following variables were related to PVT: pr... |
29,347 | Portal vein thrombosis: what is the role of genetics? | The aetiology of portal vein thrombosis (PVT) in adults is complex. Risk factors include local precipitating factors and acquired and inherited factors, an area in which there has been much recent progress. Although PVT in the absence of cirrhosis may be regarded as a somewhat different disorder to PVT in the presence ... |
29,348 | Venous thrombosis in inflammatory bowel disease. | Patients with inflammatory bowel disease (IBD) have a threefold increased risk of venous thrombosis, a major cause of morbidity and mortality. Although the exact mechanism explaining the initiation of thrombosis remains unclear, it is likely to be a multifactorial process. Reported abnormalities include activation of m... |
29,349 | Pulmonary vasculitis in behcet disease: a cumulative analysis. | The aims of this study were to investigate the frequency of pulmonary problems in Behçet disease (BD), and to discuss lesser-known features of pulmonary BD such as clinical characteristics, analysis of prognosis, and evaluation of treatment options with respect to the previously published cases.</AbstractText>We c... |
29,350 | Malign cystic glucagonoma presented with diabetic ketoacidosis: case report with an update. | A 44-year-old woman was diagnosed with type II diabetes in 1998 and 1 year later she developed necrolytic migratory erythema, which is a specific skin lesion of glucagonoma. During the clinical investigation, a nodular 6 cm mass in the distal pancreatic region and multiple cystic liver metastases were found. She was op... |
29,351 | Stents in common iliac vein obstruction with acute ipsilateral deep venous thrombosis: early and late results. | To evaluate, by imaging and clinical follow-up, the effectiveness and long-term results of stent placement in cases of common iliac vein obstruction associated with ipsilateral deep vein thrombosis (DVT).</AbstractText>Retrospective analysis of 22 patients (13 women, nine men; median age, 58 years) with common iliac ve... |
29,352 | Factor V Leiden and postoperative deep vein thrombosis in patients undergoing open Roux-en-Y gastric bypass surgery. | Patients undergoing bariatric surgery are at risk for deep venous thrombosis (DVT) and fatal pulmonary embolus. In the presence of genetic hypercoagulable disorders, accepted methods of DVT prophylaxis utilizing sequential compression devices and subcutaneous unfractionated heparin may not be adequate to prevent DVT or... |
29,353 | A prospective study of antibodies to beta2-glycoprotein I and prothrombin, and risk of thrombosis. | Antiphospholipid syndrome (APS) is a clinical autoimmune disorder characterized by thrombosis/pregnancy morbidity associated with the persistence of lupus anticoagulant (LA) and/or anticardiolipin (aCL) antibodies. We assessed the contribution of antibodies to beta2-glycoprotein I (anti-beta2GPI) and prothrombin (anti-... |
29,354 | Prothrombotic conditions, oral contraceptives, and the risk of ischemic stroke. | The role of inherited prothrombotic conditions, including factor V Leiden (FV G1691A), prothrombin G20210A, and the methylenetetrahydrofolate reductase (MTHFR) C677T genotype, in the pathogenesis of ischemic stroke is not well established. The effects of these factors may be potentiated by the use of oral contraceptive... |
29,355 | Prevention of venous thromboembolism after acute ischemic stroke. | Venous thromboembolism (VTE) is a common complication after acute ischemic stroke. When screened by 125I fibrinogen scanning or venography, the incidence of deep-vein thrombosis (DVT) in stroke patients is comparable with that seen in patients undergoing hip or knee replacement. Most stroke patients have multiple risk ... |
29,356 | The presence of IgG antibodies against beta2-glycoprotein I predicts the risk of thrombosis in patients with the lupus anticoagulant. | Lupus anticoagulant (LA) is a strong risk factor of thrombosis. However, a subgroup of patients positive for LA is unaffected by thrombosis and currently no predictive markers are available to identify patients positive for LA at increased risk for thrombosis.</AbstractText>The aim of the study was to investigate wheth... |
29,357 | High vs. low doses of low-molecular-weight heparin for the treatment of superficial vein thrombosis of the legs: a double-blind, randomized trial. | In contrast with extensive information on the management of deep vein thrombosis of the lower extremities, little is known on the most appropriate treatment of the superficial vein thrombosis (SVT). In a multicenter, prospective, controlled, double-blind, double-dummy clinical trial, 164 consecutive patients with acute... |
29,358 | Duration of anesthesia and venous thromboembolism after hip and knee arthroplasty. | To determine whether longer duration of anesthesia predisposes patients undergoing orthopedic surgery to venous thromboembolism (VTE).</AbstractText>We conducted a secondary analysis of a retrospective case-control study that examined risk factors for postoperative VTE in postmenopausal women. We matched women aged 50 ... |
29,359 | Long-haul air travel before major surgery: a prescription for thromboembolism? | To investigate the Incidence of postoperative venous thromboembolism (VTE) in patients who had flown long distances before major surgery.</AbstractText>Using the Mayo Clinic computerized patient database, we Identified patients who had flown more than 5000 km before major surgery (travelers) and had experienced an epis... |
29,360 | Cataract surgery combined with intravitreal injection of triamcinolone acetonide. | To evaluate whether the addition of cataract surgery to an intravitreal injection of triamcinolone acetonide markedly increases frequency and spectrum of complications.</AbstractText>The comparative nonrandomized clinical interventional investigation included a study group of 60 eyes (56 patients) undergoing cataract s... |
29,361 | Anticardiolipin IgG antibody and homocysteine as possible risk factors for retinal vascular occlusive disease in thai patients. | To assess the role of serum anticardiolipin IgG antibody and fasting plasma homocysteine levels as risk factors for retinal vascular occlusive disease in Thai patients.</AbstractText>This is a retrospective, case-control study. Forty-one consecutive patients with recent onset of retinal vascular occlusive diseases were... |
29,362 | Laparoscopic lymphadenectomy for gynecologic malignancies using ultrasonically activated shears: analysis of first 100 cases. | To evaluate the feasibility, safety and utility of the ultrasonic shears for laparoscopic pelvic and para-aortic lymph node retrieval in the treatment of gynecologic cancers.</AbstractText>Data on laparoscopic lymphadenectomy performed for gynecologic malignancies using ultrasonic shears over a 5-year period were colle... |
29,363 | The anticoagulant protein C pathway. | The anticoagulant protein C system regulates the activity of coagulation factors VIIIa and Va, cofactors in the activation of factor X and prothrombin, respectively. Protein C is activated on endothelium by the thrombin-thrombomodulin-EPCR (endothelial protein C receptor) complex. Activated protein C (APC)-mediated cle... |
29,364 | Vitrectomy with complete posterior hyaloid removal for ischemic central retinal vein occlusion: series of cases. | Central retinal vein occlusion (CRVO) is a common retinal vascular disorder with potentially complications: (1) persistent macular edema and (2) neovascular glaucoma. No safe treatment exists that promotes the return of lost vision. Eyes with CRVO may be predisposed to vitreous degeneration. It has been suggested that ... |
29,365 | Endovascular delivery of vein segments with valves versus direct anastomosis. | To demonstrate an experimental model designed to allow placement of a vein segment containing a valve into a femoral vein without the need for anastomoses or surgical incision on the target limbs.</AbstractText>Segments of jugular veins containing valves were harvested bilaterally from 7 female dogs weighing 30 to 40 k... |
29,366 | Midterm clinical result of tissue-engineered vascular autografts seeded with autologous bone marrow cells. | Prosthetic and bioprosthetic materials currently in use lack growth potential and therefore must be repeatedly replaced in pediatric patients as they grow. Tissue engineering is a new discipline that offers the potential for creating replacement structures from autologous cells and biodegradable polymer scaffolds. In M... |
29,367 | Is stroke a paradoxical embolism in patients with patent foramen ovale? | Purpose was to assess the stroke mechanism in patients with patent foramen ovale (PFO).</AbstractText>We reviewed the medical records of 111 stroke patients with PFO and sinus rhythm (PFO-S group), 25 with PFO and atrial fibrillation (AF) (PFO-AF group) and 67 with AF but not PFO (AF group), who had received contrast t... |
29,368 | Graduated compression stockings as prophylaxis for flight-related venous thrombosis: systematic literature review. | This paper reports a systematic review whose objective was to evaluate the effectiveness of graduated compression stockings as prophylaxis for flight-related venous thrombosis, including deep vein thrombosis and superficial venous thrombosis, after air travel in the general population.</AbstractText>Despite the extende... |
29,369 | Venous ulcer: epidemiology, physiopathology, diagnosis and treatment. | This review discusses the epidemiology, pathogenesis, diagnosis and current therapeutic options for venous ulcer. Venous ulcer is a severe clinical manifestation of chronic venous insufficiency (CVI). It is responsible for about 70% of chronic ulcers of the lower limbs. The high prevalence of venous ulcer has a signifi... |
29,370 | The clinical effectiveness initiative: a pharmacy analysis to improve outcomes and costs of drug therapy. | Selecting the most appropriate therapeutic regimens is one of the most complex and critical aspects of pharmacy management today, but the process is fraught with biases. Clinical pharmacists must offer balanced and unbiased opinions concerning therapies that provide the best cost-benefit ratio for their organizations. ... |
29,371 | Early complication following long bone reconstruction using vascularised fibula graft. | Long bone reconstruction using vascularized fibula graft is becoming more popular despite the difficulties and its post-operative complications. We reviewed our early experience dealing with vascularized fibula graft for the management of massive long bone defect. Thirteen patients had undergone long bone reconstructio... |
29,372 | The use and benefits of compression stocking aids. | An exploratory study was undertaken to trial various stocking aids designed for use with compression and antiembolic hosiery. Their features were identified and assessed by professionals for ease of use. Factors affecting the choice of stocking aids were the style and grade of stockings and the physical ability of user... |
29,373 | [Management of pulmonary embolism]. | Venous thromboembolism is often triggered by transient episodes of increased risk but may occur spontaneously in patients with permanently increased risk. Pulmonary embolism may cause impairment of respiratory and circulatory function which can vary in severity from silent to catastrophic. The diagnosis can be feasibly... |
29,374 | Coronary artery calcification and risk factors for atherosclerosis in patients with venous thromboembolism. | Venous thromboembolism (VTE) and atherosclerosis may be associated and may share common risk factors. We conducted a retrospective case-control study to investigate the association between VTE and coronary atherosclerotic disease (CAD) by means of measuring coronary artery calcification and evaluating clinical risk fac... |
29,375 | Menopausal hormone therapy. | Although estrogen has been clinically available for more than 6 decades, women have been confused by different opinions regarding the risks and benefits of menopausal hormone therapy (HT), estrogen therapy (ET), and estrogen-progestin therapy (EPT). The publication of recent randomized controlled trials (RCTs), notably... |
29,376 | Temporary Vena Caval Interruption and Thrombolysis in the Management of Deep Vein Thrombosis. | Temporary interruption of the inferior vena cava (IVC) with a retrievable filter should be considered in patients with objectively verified proximal deep vein thrombosis (DVT) of the legs who have a temporary contraindication to therapeutic anticoagulation, or in patients who experience severe complications from antico... |
29,377 | The challenge of diagnosing pulmonary embolism in elderly patients: influence of age on commonly used diagnostic tests and strategies. | Pulmonary embolism (PE) is a potentially fatal disease if left untreated. The prevalence of PE increases markedly with age, and its diagnosis in elderly people is difficult because many cardiopulmonary conditions may mimic clinical presentation of PE, and age may unfavorably influence the characteristics of diagnostic ... |
29,378 | Minimising the risk of heparin-induced osteoporosis during pregnancy. | Unfractionated heparin (UFH) may lead to symptomatic vertebral fractures in up to 3 out of every 100 people on long-term therapy. Ten-times that many people will experience a significant reduction in bone density leading to osteopoenia or osteoporosis. Low molecular weight heparins (LMWH) have been shown to be as effec... |
29,379 | The cerebrovascular risks associated with tamoxifen use. | Tamoxifen, a selective oestrogen receptor modulator with oestrogen antagonistic effects in the breast, is an effective treatment for breast cancer. Although tamoxifen has been shown to have favourable effects on cardiovascular risk factors, several studies have shown an increased risk of venous thrombosis and stroke. T... |
29,380 | Vascular access port (VAP) usage in large animal species. | Intravascular catheterization access for injection and sampling is one of the most common experimental surgical procedures. The vascular access port (VAP) was developed as an alternative to externalization of catheters. A VAP typically is implanted subcutaneously, with an attached catheter that is tunneled to a blood v... |
29,381 | [Thalidomide: new indications for an old drug]. | Thalidomide has several mechanisms of action: a hypnosedative effect, several immuno-modulatory properties and an anti-angiogenic action. Thalidomide has been used in several cutaneous inflammatory disorders (such as erythema nodosum leprosum in lepromatous leprosy, cutaneous lupus erythematosus, severe aphtosis), canc... |
29,382 | Orthopaedic manifestations of the antiphospholipid (Hughes) syndrome. | The antiphospholipid (Hughes) syndrome (APS), is characterized by arterial and/or venous thrombosis and pregnancy morbidity in association with antiphospholipid antibodies (aPL). Since its classical description 21 years ago, the clinical spectrum of Hughes syndrome has embraced the realms of obstetrics, nephrology, car... |
29,383 | Thrombosis in systemic lupus erythematosus: congenital and acquired risk factors. | To investigate the thrombotic tendency in patients with systemic lupus erythematosus (SLE) by evaluating congenital or acquired abnormalities associated with an increased risk of venous and/or arterial thrombosis.</AbstractText>A total of 57 patients with SLE were included in the study. Twenty-one patients (37%) had a ... |
29,384 | Systemic lupus erythematosus in a multiethnic US cohort (LUMINA): XXI. Disease activity, damage accrual, and vascular events in pre- and postmenopausal women. | To determine the differences in clinical manifestations, disease activity, damage accrual, and medication use in systemic lupus erythematosus (SLE) patients as a function of menopausal status at disease onset.</AbstractText>Women with SLE as per the criteria of the American College of Rheumatology, with disease duratio... |
29,385 | Dermatologic manifestations of the antiphospholipid syndrome: two hundred consecutive cases. | To describe dermatologic manifestations of the antiphospholipid syndrome (APS) and to investigate possible correlations between livedo reticularis and other APS manifestations.</AbstractText>We conducted a single-center study of 200 consecutive patients with primary or systemic lupus erythematosus-related APS. To quali... |
29,386 | Effects of aspirin and low-dose heparin in head and neck reconstruction using microvascular free flaps. | The success of microvascular free-tissue transfer to the head and neck has been greatly increased secondary to increased experience, yet postoperative anticoagulation continues to be routinely used to prevent pedicle thrombosis. However, there is currently no consensus as to what the ideal regimen, if any, is recommend... |
29,387 | Use of hormone replacement therapy by postmenopausal women after publication of the Women's Health Initiative Trial. | After publication of the Women's Health Initiative (WHI) trial in July 2002, many physicians discontinued hormone replacement therapy (HRT) in most of their postmenopausal patients. However, little is known about the women who remain on HRT.</AbstractText>We performed a retrospective chart analysis of 1000 postmenopaus... |
29,388 | [Prophylaxis and treatment of venous thromboembolism: the role of new antithrombotic drugs]. | Venous thromboembolic disease (VTE) is a major cause of morbidity and mortality. Unfractioned heparin, low-molecular weight heparins and vitamin K antagonists, currently used in the prophylaxis and treatment of VTE, are effective and relatively safe. Otherwise, they have some important limitations (narrow therapeutic w... |
29,389 | Retinal vascular occlusion following ocular contusion. | To describe an unusual fundus abnormality in eyes after trauma and its pathophysiologic basis.</AbstractText>Prospective, observational case series of five consecutive male patients who suffered retinal vascular occlusions after ocular contusion.</AbstractText>We present five cases of retinal vascular occlusions follow... |
29,390 | Vitrectomy and radial optic neurotomy for central retinal vein occlusion: effects on visual acuity and macular anatomy. | Central retinal vein occlusion (CRVO) is a common retinal vascular disorder and a leading cause of visual loss. It is thought to arise from vascular obstruction at the level of the lamina cribrosa. The purpose of the study reported here was to evaluate the potential benefit of radial optic neurotomy (RON) and determine... |
29,391 | Venous thromboembolic disease presenting as inferior vena cava thrombus extending into the right atrium. | With increasing use of echocardiography, especially transesophageal echocardiography, the diagnosis of intracardiac masses has surged. Masses that are most commonly seen in the atrial chambers include thrombi due to atrial fibrillation, cardiac myxomas often located in the atria, and valvular vegetations of infective e... |
29,392 | Lemierre's syndrome: a forgotten complication of oropharyngeal infection. | Lemierre's syndrome (postanginal sepsis) usually complicates an oropharyngeal infection as septicemia, septic thrombophlebitis of the internal jugular vein, and metastatic lesions, most frequently in the lungs. Fusobacterium necrophorum is the usual etiologic agent. Lemierre's syndrome is not widely known by clinicians... |
29,393 | Neovascularization in branch retinal vein occlusion combined with arterial insufficiency. | The aim of this study is to elucidate the association of neovascularization in branch retinal vein occlusion (BRVO) combined with major arterial insufficiency (MAI), compared with BRVO alone. The authors retrospectively reviewed the charts, color photographs, and fluorescein angiograms of 304 patients (308 eyes) who ha... |
29,394 | Phosphatidylserine IgG and beta-2-glycoprotein I IgA antibodies may be a risk factor for ischaemic stroke. | Antiphospholipid antibodies (APLA) are established risk factors for venous thrombosis but their role in the pathogenesis of cerebral ischaemia is unclear. The purpose of the present study was to evaluate the relevance of various APLA in patients with cryptogenic stroke (group A, n = 21) and determined causes of stroke ... |
29,395 | Life-threatening hemorrhage after dalteparin therapy in a patient with impaired renal function. | Dalteparin and other low-molecular-weight heparins are frequently used for the treatment of deep vein thrombosis and for other indications. Unlike unfractionated heparin (UFH), dalteparin is mainly cleared through the kidney; therefore, it can accumulate in patients with impaired renal function, increasing the risk of ... |
29,396 | Surgical management of hypothenar and thenar hammer syndromes: a retrospective study of 31 instances in 28 patients. | This retrospective study assessed the results of treatment of 29 cases of hypothenar hammer syndrome and two cases of thenar hammer syndrome. Three hands were symptom free, 15 were improved, 11 were unchanged and two were worse at a mean follow-up of 43 (range 4-60) months. Follow-up colour-coded Duplex sonography of r... |
29,397 | Reconstruction of the superior sagittal sinus with silicone tubing. | The authors conducted a study to develop a safe and effective intracranial venous sinus reconstruction for extensive clinical use.</AbstractText>After resecting the superior sagittal sinus (SSS), it was reconstructed in eight dogs by performing either a tube-insertion technique or end-to-end anastomosis procedure, in b... |
29,398 | Tumefaction of the dural sinuses associated with a coagulopathy following treatment of hydrocephalus in a perinate: case report. | The authors describe an infant with abnormal development of the cerebral venous system associated with in utero ventriculomegaly and perinatal hemorrhage. When the patient was 6 weeks of age progressive ventriculomegaly followed by cerebrospinal fluid diversion resulted in tumefaction of the dural sinuses, intravascula... |
29,399 | Differentiating pharmacologic agents used in catheter-directed thrombolysis. | The use of catheter-directed thrombolysis is a proven treatment for arterial ischemia, deep vein thrombosis, and severe pulmonary embolism. For arterial ischemia, thrombolysis has resulted in improved amputation-free survival and fewer subsequent surgeries to reestablish blood flow to the ischemic limb. The management ... |
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