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30,000 | Current concepts for the prevention of venous thromboembolism. | Venous thromboembolism (VTE) is a major cause of morbidity and mortality worldwide and the annual incidence of VTE is 1 per 1000. The individual risk for venous thromboembolism may be substantially higher and is determined by expositional and dispositional factors. Unfractionated heparin and warfarin have been the main... |
30,001 | [The risk of thromboembolism in airline passengers]. | Long carrier flights favor thromboembolism. The risk is well known to the general public but is probably really very low. The risk is however pertinent due to the volume of air travel in the world. Sitting in the same position for a long time induced venous stasis which is the principal factor favoring thrombosis in tr... |
30,002 | Effect of tamoxifen on venous thromboembolic events in a breast cancer prevention trial. | Tamoxifen, a selective estrogen-receptor modulator, increases venous thromboembolic events (VTE), but the factors explaining this risk are unclear. Atherosclerosis may induce VTE, or the 2 conditions may share common risk factors. We assessed the effect of tamoxifen on VTE in a breast cancer prevention trial and studie... |
30,003 | Cerebral venous sinus thrombosis in children: risk factors, presentation, diagnosis and outcome. | Neuroimaging and management advances require review of indications for excluding cerebral venous sinus (sinovenous) thrombosis (CSVT) in children. Our goals were to examine (i) clinical presentations of CSVT, (ii) prothrombotic risk factors and other predisposing events, (iii) clinical and radiological features of brai... |
30,004 | Rupture of Baker's cyst producing pseudothrombophlebitis in a patient with Reiter's syndrome. | This is an unusual case of pseudothrombophlebitis resulting from rupture of Baker's cyst in a patient with Reiter's syndrome. The patient presented with a swollen, painful left calf and persistent itching on the skin of the calf. Ultrasonography showed a ruptured popliteal cyst with minimal hemorrhage and fluid collect... |
30,005 | [Current situation and issues in preoperative autologous blood donation in Japan]. | Preoperative autologous blood donation (PABD) with no risk of blood-borne infection transmission has been considered the supreme blood transfusion therapy, and it has been reported to decrease incidence of postoperative deep-vein thrombosis. However, the need for PABD has decreased in the USA, because 1) risk of blood-... |
30,006 | Endovascular stenting to treat chronic long-segment inferior vena cava occlusion. | Chronic inferior vena cava (IVC) occlusion is often associated with debilitating symptoms. Supportive therapy is the treatment offered to most patients, often with poor symptom control. Patients have had to learn to cope with the sequelae of the syndrome and to accept lifelong disability and pain. This may no longer be... |
30,007 | Extension of saphenous thrombus into the femoral vein: a potential complication of new endovenous ablation techniques. | Endovenous techniques such as radiofrequency ablation (RFA) and endovenous laser therapy (ELT) have emerged as percutaneous minimally invasive procedures for ablation of incompetent great saphenous veins in patients with varicosity and venous insufficiency. Early reports showed safety and efficacy of both techniques, w... |
30,008 | Use of short PTFE segments (<6 cm) compares favorably with pure autologous repair in failing or thrombosed native arteriovenous fistulas. | The re-establishment of patency in a stenosed or thrombosed native arteriovenous fistula (AVF) is fundamental to regaining adequate hemodialysis through the same cannulable vein. Many surgeons have been reluctant to use even small segments of synthetic grafts in AVF revisions because of a perception that these would le... |
30,009 | Mesenteric venous thrombosis with transmural intestinal infarction: a population-based study. | To determine the cause-specific mortality from and incidence of transmural intestinal infarction caused by mesenteric venous thrombosis (MVT) in a population-based study and to evaluate the findings at autopsy by evaluating autopsies and surgical procedures.</AbstractText>All clinical (n = 23,446) and forensic (n = 756... |
30,010 | Prevalence and risk of pulmonary embolism in patients with intracardiac thrombosis: a population-based study of 23 796 consecutive autopsies. | While right intracardiac thrombosis (IT) is a potential cause of pulmonary embolism (PE) similar to that of stroke in left-sided IT, its prevalence and prognostic significance has not been studied in the general population. The aim of this study was to assess the age- and gender-specific prevalence of IT and its relati... |
30,011 | [The serratus anterior free flap in limb reconstruction. About 30 cases]. | Between 2001 and 2003, 30 serratus anterior free flaps have been realized in our unit for reconstruction of lower limb. The flaps were indicated for repair of traumatic soft tissue defect in 19 cases, for chronic wound in six cases, for purpura fulminans in two cases, for pressure sore in one case and after tumor resec... |
30,012 | [Anterolateral thigh flap. Retrospective study]. | The anterolateral thigh flap is a cutaneous or fasciocutaneous perforator flap, extensively used in China, Japan, Taiwan (Demirkan et al., 2000; Kimata et al., 1997; Koshima et al., 1993; Luo et al., 1999) but infrequently in Europe, probably because of variations in origin and course of the cutaneous perforators rendi... |
30,013 | 'Extension technique': a modified technique for brachio-cephalic fistula to prevent dialysis access-associated steal syndrome. | To describe a modification in brachio-cephalic fistula formation for prevention of dialysis access-associated steal syndrome (DASS).</AbstractText>Short report.</AbstractText>From September 2001 to December 2003, 32 upper arm autogenous fistulae were formed using the 'extension technique' in patients at high-risk for d... |
30,014 | Can thromboembolism be the result, rather than the inciting cause, of acute vascular events such as stroke, pulmonary embolism, mesenteric ischemia, and venous thrombosis?: a maladaptation of the prehistoric trauma response. | Thromboembolism is considered the inciting cause of many vascular disorders including acute coronary syndrome (ACS), ischemic stroke, pulmonary embolism (PE), deep vein thrombosis (DVT), and mesenteric ischemia. Adrenergia and inflammation are known to accompany these conditions, particularly among arterial thromboembo... |
30,015 | [Misdiagnosis of venous thrombosis in childhood]. | Thrombotic events are often diagnosed with a delay that may be responsible for definite post-thrombotic syndrome.</AbstractText>We report two cases, which emphasize the difficulty of the diagnosis of venous thrombosis in two boys, at age 11 and 12 respectively. The occurrence of a leg pain led to a misdiagnosis of arth... |
30,016 | Association of the R92Q TNFRSF1A mutation and extracranial deep vein thrombosis in patients with Behçet's disease. | Behçet's disease is a chronic, relapsing, multisystemic inflammatory disorder characterized by recurrent oral and genital ulcers and by ocular, articular, vascular, and central nervous system involvement. The tumor necrosis factor alpha (TNFalpha) pathway is likely involved in the pathophysiology of Behçet's ... |
30,017 | Leg length preservation with pedicled fillet of foot flaps after traumatic amputations. | Six patients with insufficient soft-tissue coverage after lower limb trauma were treated with pedicled fillet of foot flaps to achieve primary stump closure and to preserve leg length. The flaps used were all based on either the posterior tibial neurovascular pedicle, the anterior tibial neurovascular pedicle, or both.... |
30,018 | Thromboembolism in plastic surgery. | Thromboembolism is a dreaded complication of surgery in multiple disciplines, including plastic surgery, and deep venous thrombosis and pulmonary embolus cause significant morbidity, even death. This article provides methods for understanding and preventing deep venous thrombosis and pulmonary embolus in plastic surger... |
30,019 | Virchow's triad revisited: abnormal flow. | Virchow rightly recognised that blood flow plays an important role in thrombosis. The roles of blood flow in haemostasis, and in arterial, intra-cardiac, and venous thrombosis are reviewed. In streamline (laminar) flow, shear stresses are maximal at the vessel wall, and affect endothelial cell morphology and function (... |
30,020 | Fibrin stabilization (factor XIII), fibrin structure and thrombosis. | Factor XIII (FXIII) is a zymogen that is converted into an active transglutaminase (FXIIIa) by the concerted action of thrombin and Ca2+. Its main task is to crosslink alpha-, and gamma-chains of fibrin and alpha2-plasmin inhibitor to fibrin. By this way FXIIIa strengthens fibrin and protects it from the prompt elimina... |
30,021 | Elevated clotting factor levels and venous thrombosis. | Increased plasma levels of fibrinogen, factor VIII (FVIII), factor IX (FIX), factor XI (FXI) and prothrombin all were reported to be independent risk factors of venous thromboembolism (VTE). However there is only limited information on the molecular basis of these plasma phenotypes. In addition some of these plasma phe... |
30,022 | Assessment of the risk and prophylactic treatment of venous thromboembolism in the elderly. | Numerous large randomized controlled trials have assessed the benefit of prophylactic anticoagulation for venous thromboembolism in selected patients. However, few trials were conducted in elderly patients, as this issue was not addressed in this specific population,or as elderly patients were excluded of these studies... |
30,023 | Assessment of the risk and the prophylaxis of venous thromboembolism in surgical patients. | This review article first deals with risk factors for developing postoperative venous thromboembolism. The various pharmacological prophylactic methods available today are summarized with focus on dominating method low molecular weight heparin and the two new ones, the Xa inhibitor fondaparinux and the IIa inhibitor xi... |
30,024 | Risk factors of recurrent venous thromboembolism: the role of residual vein thrombosis. | In 313 consecutive symptomatic outpatients with proximal deep vein thrombosis (DVT) who had a conventional anticoagulation, an ultrasound assessment of the common femoral and the popliteal vein was performed three months after the acute episode, and then at 6, 12, 24, and 36 months. Veins were considered as recanalized... |
30,025 | Homocysteine, vitamin B6 and the risk of recurrent venous thromboembolism. | Hyperhomocysteinemia (HHC) is an independent risk factor for cardiovascular disease, and even mildly to moderately elevated homocysteine levels have been associated with a heightened risk for a first and recurrent venous thromboembolism (VTE). Within the frame of a large prospective cohort study (Austrian Study on Recu... |
30,026 | Gene-gene and gene-environment interactions in mild hyperhomocysteinemia. | Mild/moderate hyperhomocysteinemia (HHcy), a highly prevalent condition, is independently associated with an increased risk of arterial and venous thromboembolic diseases. Early reports of the association of mild/moderate HHcy with juvenile venous thromboembolism have shown familiarity for HHcy in relatives of index ca... |
30,027 | Management of patients with acute venous thromboembolism: findings from the RIETE registry. | Guidelines for the treatment of venous thromboembolism (VTE) are mainly based on randomized controlled trials, but a number of patients with VTE are excluded from trials due to co-morbidities (i.e., recent bleeding, renal insufficiency, thrombocytopenia, abnormal prothrombin time or pregnancy). Thus, treatment regimens... |
30,028 | Extended versus rapid analysis of the leg vein system: a multicenter ultrasound study (the ERASMUS study)--an interim analysis. | The reliability of diagnostic strategies based on compression ultrasonography (CUS) for the diagnosis of proximal deep venous thrombosis (DVT) in symptomatic (out)patients is well documented; however these approaches never gained widespread application.Echo-color-Doppler (ECD), is regularly adopted by vascular laborato... |
30,029 | Controversial issues in the diagnosis of venous thromboembolism. | Although considerable progress has been made in the diagnosis of venous thromboembolism, several issues remain that are awaiting a proper solution. Among them are: the respective role of compression ultrasound of the proximal veins and ultrasonography of the entire leg vein system in the diagnostic approach of patients... |
30,030 | Antiphospholipid syndrome: association between laboratory tests and clinical practice. | Antiphospholipid antibodies are a wide and heterogeneous group of immunoglobulins, whose presence inpatients with arterial and venous thrombosis, and obstetrical complications defines the antiphospholipid syndrome. We systematically reviewed published articles on this syndrome to investigate the association between thr... |
30,031 | [Arterial thrombosis and genetic polymorphisms: too many actors, complex scenario]. | Arterial thrombosis results from complex gene-gene and gene-environment interactions. While Vichow's triad was traditionally referred to venous thrombosis, the same process has been applied to arterial thrombosis: abnormalities of hemorrheology, abnormal blood constituents and abnormal vessel wall/endothelial dysfuncti... |
30,032 | Review article: diagnosis and management of mesenteric ischaemia with an emphasis on pharmacotherapy. | Mesenteric ischaemia results from decreased blood flow to the bowel, causing cellular injury from lack of oxygen and nutrients. Acute mesenteric ischaemia (AMI) is an uncommon disorder with high morbidity and mortality, but outcomes are improved with prompt recognition and aggressive treatment. Five subgroups of AMI ha... |
30,033 | Absence of factor V Arg306--Thr and low factor V Arg306->Gly mutation prevalence in Thai blood donors. | Thrombosis among the Thai population is much lower than in western countries. The Thai population is protected to some extent against familial thrombophilia as by the very low prevalence of factor V Leiden, G20210A prothrombin and C677T methylenetetrahydrofolate reductase mutations. The present study reports the preval... |
30,034 | [Surgical reduction of fat surplus leading to pulmonary embolism]. | Surgical reduction of fat surplus is usually performed on healthy individuals and is reported as a safe procedure as it is not associated with a lethal outcome. Due to the anticipation of peri- and postoperative bleeding as a result of the large wound area, which may have a negative influence on the cosmetic result, pa... |
30,035 | Urgent subtotal colectomy for severe inflammatory bowel disease. | The purpose of this study was to assess the safety of subtotal colectomy and outcomes after this procedure in the modern era of immunosuppressive agents and primary pelvic pouch surgery.</AbstractText>All patients undergoing subtotal colectomy with ileostomy for ulcerative colitis or Crohn's colitis from July 1, 1990 t... |
30,036 | A rare case of complex vascular reconstruction in liver transplantation. | Abnormalities of recipient or donor vascular structures are associated with reconstructive difficulties in liver transplantation. A patient with thrombosis of the right hepatic vein and associated stricture of the inferior vena cava (IVC), portal vein thrombosis and multiple aberrant arteries underwent orthotopic liver... |
30,037 | Stability results of hamstring anterior cruciate ligament reconstruction at 2- to 8-year follow-up. | The purpose of this study was to test the hypothesis that hamstring (HS) anterior cruciate ligament (ACL) reconstructions using EndoButton (Smith & Nephew, Andover, MA) femoral and whipstitch/screw tibial fixation can produce a high rate of objective stability in a population of reconstructed patients with low morb... |
30,038 | Early treatment of cystoid macular edema secondary to branch retinal vein occlusion with intravitreal triamcinolone acetonide. | To determine the efficacy of intravitreal triamcinolone acetonide (IVTA) in the early treatment of severe cystoid macular edema (CME) related to acute branch retinal vein occlusion.</AbstractText>Retrospective, non-comparative case series. Twelve eyes with severe CME (foveal thickness > 450 microm) secondary to acut... |
30,039 | [Abdominal pain in liver cirrhosis patient--an unusual case]. | We present the case of a 62 years male subjects, known with liver cirrhosis diagnosed in 2000 during a laparoscopy. The subject presented with important atypical abdominal pain, leucocytosis, thrombocytosis, small ascites; pneumatosis and hydro-aeric images of small intestine at abdominal X Ray, thickened bowel wall at... |
30,040 | Cardiovascular complications associated with cocaine use. | Cocaine use in North America has reached epidemic proportions becoming one of the top causes of drug-related visits to US emergency rooms. The number of users has increased due to the popularity and accessibility of crack cocaine. The pharmacokinetic properties and effects of cocaine on the cardiovascular system can le... |
30,041 | Intermittent pneumatic compression in the prevention of venous thromboembolism in high-risk trauma and surgical ICU patients. | Our aim was to evaluate the efficacy and safety of intermittent pneumatic compression methods (IPC) in the prevention of deep venous thrombosis (DVT) and pulmonary embolism (PE) in high-risk patients followed in our intensive care unit (ICU) for whom anticoagulation is contraindicated due to high risk of bleeding.</Abs... |
30,042 | The surgeon's role in breast cancer chemoprevention. | An individual woman's level of risk for the development of invasive breast cancer can be accurately estimated using the Gail model. This model is not appropriate for use in women with prior breast cancer (invasive or in situ) or a family history suggestive of a genetic predisposition. Tamoxifen is an option for breast ... |
30,043 | Resection of phaeochromocytoma extending into the right atrium in a patient with multiple endocrine neoplasia type 2A. | We report the first case of successful surgical resection of a malignant phaeochromocytoma with tumour extension into vena cava and right atrium in a patient with multiple endocrine neoplasia type 2A. A 21-year-old woman with genetic confirmation of multiple endocrine neoplasia type 2A syndrome was diagnosed with a ver... |
30,044 | Deep vein thrombosis during rabbit antithymocyte globulin administration. | Rabbit antithymocyte globulin (RATG) is recommended for central administration, and no evidence justifies the common practice of adding heparin to the bag, but the evaluation of thrombocytopenia may be complicated by coadministration. We recently phased out the use of heparin in RATG in our kidney and kidney-pancreas t... |
30,045 | Transplantation of pediatric kidneys to adult recipients: an analysis of 13 cases. | The shortage of cadaveric donors for kidney transplantation has prompted many centers to expand the criteria used for donor selection to increase the organ supply. The use of cadaveric pediatric kidneys has been suggested as a means to overcome the shortage. However, some studies indicate that kidneys from pediatric do... |
30,046 | Procedures for the outpatient management of patients with deep venous thrombosis. | Although deep venous thrombosis (DVT) is now widely managed on an outpatient basis, at a practical level there remains a potential for uncertainty as to which patient might prove suitable and in particular in regard to the lines of responsibility of each department involved in the delivery of clinical care. This guidel... |
30,047 | Individual time within target range in patients treated with vitamin K antagonists: main determinant of quality of anticoagulation and predictor of clinical outcome. A retrospective study of 2300 consecutive patients with venous thromboembolism. | The efficacy and safety of vitamin K antagonists (VKA) are related to the actual level of anticoagulation (given as the international normalized ratio, INR). It is often difficult to maintain an optimal INR over time. We assessed the clinical impact of the individual time spent within INR target range (ITTR) in 2304 co... |
30,048 | Percutaneous balloon cryoplasty: a new therapy for rapidly recurrent anastomotic venous stenoses of hemodialysis grafts? | Vascular access dysfunction is a major source of morbidity for end-stage renal disease patients on hemodialysis. The arteriovenous graft is a common access type for many of these patients. Frequent stenosis formation and thrombosis complicate this form of access. Patients may have a rapidly forming and recurrent venous... |
30,049 | Oral anticoagulation: challenges in the case-management setting. | By understanding barriers, providing education, and advocating appropriate treatment, case managers play an essential role in the prevention and treatment of thromboembolic disorders. Yet, thromboembolic events such as stroke and deep-vein thrombosis still result in substantial morbidity and mortality despite the avail... |
30,050 | Multiplex PCR-RFLP assay for detection of factor V Leiden and prothrombin G20210A. | Factor V Leiden and prothrombin G20210A are clinically relevant genetic risk factors for venous thrombosis. Molecular diagnostic testing for factor V Leiden and prothrombin G20210A is widespread, and laboratories use a variety of technical approaches. Here we introduce a multiplex polymerase chain reaction-restriction ... |
30,051 | Prevention of thrombosis with prostaglandin E1 in a patient with catastrophic antiphospholipid syndrome. | Catastrophic antiphospholipid syndrome (CAPS) is a variant of antiphospholipid syndrome and presents with life-threatening symptoms of multiorgan failure due to thrombosis. We present a patient with CAPS secondary to an ovarian cancer. In such cases, it is believed that the thrombotic risk disappears after surgical rem... |
30,052 | Catheter-directed thrombolysis for the management of postpartum deep venous thrombosis. | Catheter-directed thrombolysis that removes the thrombus and restores patency of the veins appears to be a safe and effective management of acute deep venous thrombosis (DVT). It has been shown to reduce long-term postthrombotic morbidity and improve the quality of life. Pregnancy and the postpartum period are generall... |
30,053 | [A case of ulcerative colitis successfully treated with low-dose warfarin for portal vein thrombosis after colectomy].<Pagination><StartPage>25</StartPage><EndPage>30</EndPage><MedlinePgn>25-30</MedlinePgn></Pagination><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tomita</LastName><ForeName>Junko</ForeName><... | Performance improvements have brought about fundamental changes in the past year at Walter Reed Army Medical Center (WRAMC), where a concerted effort is underway to put current research into clinical practice. Tracheostomy care and suctioning became the pilot procedure for these changes in November 2002. What began as ... |
30,054 | Establishment of a new pig model for auxiliary partial orthotopic liver transplantation. | To establish a new pig model for auxiliary partial orthotopic liver transplantation (APOLT).</AbstractText>The liver of the donor was removed from its body. The left lobe of the liver was resected in vivo and the right lobe was used as a graft. After the left lateral lobe of the recipient was resected, end-to-side anas... |
30,055 | Recombinant coagulation factor VIIa in major liver resection: a randomized, placebo-controlled, double-blind clinical trial. | Prevention of bleeding episodes in noncirrhotic patients undergoing partial hepatectomy remains unsatisfactory in spite of improved surgical techniques. The authors conducted a randomized, placebo-controlled, double-blind trial to evaluate the hemostatic effect and safety of recombinant factor VIIa (rFVIIa) in major pa... |
30,056 | Powerful inflammatory properties of large vein endothelium in vivo. | Inflammatory responses of large vein endothelium are of importance in pathological processes such as venous thrombosis, chronic venous congestion, and vein graft atherosclerosis. However, the inflammatory properties of large vein endothelium are unclear.</AbstractText>In this study, we used several microscopy technique... |
30,057 | Inflammatory joint disease and severe ischemia of the extremities revealing thromboangiitis obliterans in a female. | Thromboangiitis obliterans (or Buerger disease) is a rare vascular disease that selectively affects young males who are inveterate smokers. We report a case in a young female smoker who presented with recurrent episodes of polyarthralgia and distal extremity ischemia. The initial diagnosis was connective tissue disease... |
30,058 | [Pathogenic roles of anti-beta2-GPI antibody in patients with antiphospholipid syndrome]. | Antiphospholipid syndrome (APS) is characterized by arterial and/or venous thrombosis and pregnancy morbidity in the presence of antiphospholipid antibodies (aPL). Beta2-glycoprotein I (beta2-GPI) and prothrombin are representative autoantigens, the former more extensively investigated. Anti-beta2-GPI antibodies are no... |
30,059 | [The content of D-dimer in peripheral blood as observed studied in thrombohemorrhagic lesions of the retina]. | The content of D-dimer in peripheral blood was studied in thrombohemorrhagic lesions of the retina. 60 patients with retinal pathology of the retina, i.e. thrombosis of retinal veins, exudative-hemorrhagic stage of central chorioretinal dystrophy and preproliferative diaichbetic retinopathy with pronounced exudative he... |
30,060 | Thrombophilia in children with cystic fibrosis. | In some children with cystic fibrosis (CF), percutaneous long lines occlude sooner than expected (due to thrombophlebitis or thrombosis), and many have a totally implantable venous access device (TIVAD), a recognized complication of which is thrombosis. This complication is more likely if the child has an underlying th... |
30,061 | Polymorphonuclear leukocyte integrins in deep venous thrombosis. | The polymorphonuclear leukocytes (PMN) have a role in the pathophysiology of deep venous thrombosis (DVT). We examined the phenotypical expression of PMN beta(2M)-integrins (CD ll a, CDll b, CD 11c) in a group of 19 subjects with leg DVT. PMN cells were incubated with fluorescent monoclonal antibodies against CD11a, CD... |
30,062 | Low-molecular-weight heparin for the treatment of venous thromboembolism in the elderly. | Venous thromboembolism (deep vein thrombosis and/or pulmonary embolism) is a common problem in the elderly population. Indeed, increasing age is a significant risk factor for venous thromboembolism. The treatment of venous thromboembolism in the elderly population presents certain unique problems related to aging, such... |
30,063 | Iliac vein compression and pulmonary embolism in a long distance runner: computed tomography and magnetic resonance imaging-a case report. | Iliac vein compression is invoked as the explanation for deep venous thrombosis occurring more often in the left iliofemoral system than the right. The authors report a previously undescribed variant of iliac compression whereby a left iliac arterial aneurysm caused venous compression and resultant thrombosis. In this ... |
30,064 | Liposomal heparin spray: a new formula in adjunctive treatment of superficial venous thrombosis. | The objective of this study was to assess the efficacy and safety of liposomal heparin spray-a new formula of topical heparin delivery. This was a randomized, multicenter, controlled open clinical trial with 2 parallel groups. Forty-six outpatients with clinical signs of superficial venous thrombosis (SVT) were treated... |
30,065 | Near-infrared fluorescent imaging of cerebral thrombi and blood-brain barrier disruption in a mouse model of cerebral venous sinus thrombosis. | An intravital microscopy imaging method was developed to visualize active cerebral thrombus and blood-brain barrier (BBB) disruption using Near Infrared Fluorescent (NIRF) probes. A circular craniotomy was made in CD-1 mice. Thrombi were formed by applying 10%-FeCl3 to the entire exposed superior sagittal sinus (SSS, 5... |
30,066 | The effect of screening for deep vein thrombosis on the prevalence of pulmonary embolism in patients with fractures of the pelvis or acetabulum: a review of 973 patients. | In patients with pelvic or acetabular fractures, to compare the prevalence of pulmonary embolism in a time period without screening for deep vein thrombosis to that seen when a screening protocol was in place.</AbstractText>Retrospective.</AbstractText>County hospital.</AbstractText>All patients with closed fractures o... |
30,067 | Homocysteine induces cell cycle G1 arrest in endothelial cells through the PI3K/Akt/FOXO signaling pathway. | High levels of homocysteine (Hcy) induce a sustained injury on arterial endothelial cells, which accelerates the development of thrombosis and atherosclerosis. Hcy specifically inhibits the growth of endothelial cells. The present study investigated the signaling pathways underlying this cell-cycle effect.</AbstractTex... |
30,068 | Central venous catheter-related complications in children with oncological/hematological diseases: an observational study of 418 devices. | The use of indwelling central venous catheters (CVCs) has become commonplace in the management of children undergoing anticancer treatment. Several types of CVC are available, while information on complications observed in children is scarce. We describe the experience of two tertiary care centers in Italy that prospec... |
30,069 | Hematologic ramifications of patent foramen ovale--role of hypercoagulable state. | This article discusses the ramifications of a hypercoagulable state in patients with a patent foramen ovale. |
30,070 | Validation of the anti-factor Xa assay for the potency assessment of enoxaparin in pharmaceutical formulations. | Enoxaparin is a low-molecular weight heparin used clinically for the prevention and treatment of venous and arterial thrombosis. An anti-factor Xa assay was used to evaluate the potency of the final drug preparation. Method validation investigated parameters such as the range, linearity (r2 = 0.9971), precision, accura... |
30,071 | [Diagnosis and treatment for limb edema due to venous disease]. | We described the diagnosis and treatment for limb edema due to venous disease in this paper. Venous limb edema is caused by vein pressure elevation, which is induced by venous reflux, flow disturbance and overflow. Valve incompetence causes varicose vein and deep venous insufficiency of lower extremities. Deep vein thr... |
30,072 | The heparins and cancer: review of clinical trials and biological properties. | The association between cancer and thromboembolic disease is a well-known phenomenon and can contribute significantly to the morbidity and mortality of cancer patients. The spectrum of thromboembolic manifestations in cancer patients includes deep vein thrombosis, pulmonary embolism, but also intravascular disseminated... |
30,073 | Thrombolytic agents for arterial and venous thromboses in neonates. | Clinically symptomatic thromboses are infrequent but serious complications in infants undergoing intensive care. Most are related to central vascular catheters. Symptomatic thrombosis may cause severe morbidity due to irreversible organ damage and also loss of limbs.</AbstractText>To assess the efficacy and safety of t... |
30,074 | Improvement of liver function after surgery for Budd-Chiari syndrome. | We evaluated the relationship between liver histology and postoperative improvement of liver function after surgery for Budd-Chiari syndrome (BCS).</AbstractText>Over a period of 23 years, we operated on 46 patients with BCS by reconstructing the occluded inferior vena cava (IVC) and reopening as many occluded hepatic ... |
30,075 | Salvage of thrombosed dialysis access grafts with venous anastomosis stents. | Thrombosis of arteriovenous (AV) grafts caused by stenosis at the venous anastomosis is a well-described problem. Surgical thrombectomy and conventional angioplasty with mechanical thrombectomy have provided good success rates in achieving immediate graft patency but with generally dismal graft survival rates in the ra... |
30,076 | [Factors affecting quality of care for elderly subjects undergoing surgery for hip fracture: review of the literature]. | Hip fractures are one of the leading causes for admission of elderly subjects to healthcare facilities. Because of population aging, the incidence of hip fractures has increased considerably over the last years and will continue to increase in industrialized countries. Hip fracture in an elderly subject may be life thr... |
30,077 | Barriers to the use of outpatient enoxaparin therapy in patients with deep venous thrombosis. | To establish a clinical pathway for outpatient enoxaparin therapy in deep venous thrombosis (DVT) and then characterize its implementation and barriers to use.</AbstractText>Single institution, prospective, observational study of consecutive adult emergency department patients (age > or =18 years) who had a diagnosi... |
30,078 | Clinicians' response to radiologists' reports of isolated subsegmental pulmonary embolism or inconclusive interpretation of pulmonary embolism using MDCT. | The purpose of our study was to investigate clinician response and patient outcome associated with the radiologist's report of isolated subsegmental pulmonary emboli (ISSPE) or indeterminate or inconclusive results on MDCT for venous thromboembolism.</AbstractText>All patients were examined using 8- or 16-MDCT. Reporte... |
30,079 | Augmentation in lower extremity sonography for the detection of deep venous thrombosis. | The purpose of our study was to evaluate the usefulness of venous flow augmentation with duplex sonography in the evaluation of deep venous thrombus of the lower extremities.</AbstractText>The augmentation component of the lower extremity sonogram rarely provides additional information in the diagnosis of deep venous t... |
30,080 | Thromboembolic disease detection at indirect CT venography versus CT pulmonary angiography. | To assess the incremental increase in thromboembolic disease detection at indirect computed tomographic (CT) venography versus CT pulmonary angiography and to determine the importance of scan interval for indirect CT venography on the basis of thrombus length.</AbstractText>Institutional review board approval was obtai... |
30,081 | Decreased prothrombotic effects of pegylated recombinant human megakaryocyte growth and development factor in thrombocytopenic state in a rat thrombosis model. | Previous in vitro studies demonstrated that thrombopoietin (TPO) acts on platelets to activate a variety of intracellular signaling pathways and to enhance platelet sensitivity to multiple agonists. Little is known, however, about whether TPO exerts prothrombotic effects in vivo. The aim of this study was to examine th... |
30,082 | The incidence of venous thromboembolism among Factor V Leiden carriers: a community-based cohort study. | While Factor V (FV) Leiden is a risk factor for venous thromboembolism (VTE), the incidence of VTE among FV Leiden carriers is uncertain. The objective of the study was to estimate the overall age-specific and pregnancy-related VTE incidence and the relative risk among FV Leiden carriers. In a community-based sample of... |
30,083 | ABO blood groups and risk of venous thromboembolism during pregnancy and the puerperium. A population-based, nested case-control study. | To examine possible associations of ABO blood types with the risk of venous thromboembolism (VTE) in pregnancy and the puerperium.</AbstractText>We conducted a nested case-control study within a cohort of 71,729 women who gave birth to 126,783 children in the North Jutland County, Denmark, from 1980 to 2001. We identif... |
30,084 | Homocysteine, MTHFR and risk of venous thrombosis: a meta-analysis of published epidemiological studies. | It has been suggested that elevated total plasma homocysteine levels are associated with the risk of venous thrombosis.</AbstractText>To assess the relationship of homocysteine and the MTHFR 677TT genotype and the risk of venous thrombosis by conducting a meta-analysis of all relevant studies.</AbstractText>Studies (ca... |
30,085 | Video laparoscopic surgery: is out-of-hospital thromboprophylaxis necessary? | Despite widespread use of laparoscopic procedures, no adequate data are available to support specific recommendations for venous thromboprophylaxis in patients undergoing laparoscopic surgery. This prospective, randomized trial is the first to be designed to evaluate a regimen of out-of-hospital thromboprophylaxis afte... |
30,086 | Extended anticoagulation therapy for the primary and secondary prevention of venous thromboembolism. | Extending the period of anticoagulation is an active area of investigation in both primary and secondary prevention of venous thromboembolic disease. In orthopaedic surgery, particularly in patients undergoing hip surgery, there is a growing interest in using extended anticoagulation beyond that traditionally given in ... |
30,087 | Cardiovascular risk factors in middle-aged women and the association with use of hormone therapy: results from a population-based study of Swedish women. The Women's Health in the Lund Area (WHILA) Study. | Cardiovascular diseases in women are multifactorial. Women carry different risk factors compared to men and these specific risk factors need to be delineated, particularly in relation to the hormonal situation, and effects of diet and lifestyle.</AbstractText>Out of the total cohort of 10,766 women born 1935-1945 livin... |
30,088 | Large granular lymphocyte (LGL)-like clonal expansions in paroxysmal nocturnal hemoglobinuria (PNH) patients. | In paroxysmal nocturnal hemoglobinuria (PNH), clonal expansion of glycosylphosphatidylinositol-anchored proteins (GPI-AP)-deficient cells leads to a syndrome characterized by hemolytic anemia, marrow failure, and venous thrombosis. PNH is closely related to aplastic anemia and may share its immune pathophysiology. In v... |
30,089 | Is wound drainage necessary after lumbar spinal fusion surgery? | Despite a lack of any evidence to support the utilization of closed-suction drainage after spinal surgery, it is a frequently utilized procedure.</AbstractText><AbstractText Label="MATERIAL/METHODS" NlmCategory="METHODS">A retrospective evaluation of eighty-five consecutive posterior lumbar fusions at a single level fo... |
30,090 | Sequential mitoxantrone/prednisone followed by docetaxel/estramustine in patients with hormone refractory metastatic prostate cancer: results of a phase II study. | Mitoxantrone/prednisone ameliorates symptoms in hormone refractory prostate cancer (HRPC) but has no effect on survival. Docetaxel (Taxotere)/estramustine improves response but with significant toxicity. We reasoned that a sequential administration of the two regimens could be a viable alternative for delivering full d... |
30,091 | Characterization of a small molecule PAI-1 inhibitor, ZK4044. | Plasminogen activator inhibitor-1 (PAI-1) is a key negative regulator of the fibrinolytic system. In animal studies, inhibition of PAI-1 activity prevents arterial and venous thrombosis, indicating that PAI-1 inhibitors may be used as a new class of antithrombotics. In this study, we characterize a small molecule PAI-1... |
30,092 | Thrombin activatable fibrinolysis inhibitor in Behçet's disease. | Thrombin activatable fibrinolysis inhibitor (TAFI) is a procarboxypeptidase downregulating plasmin formation, thereby causing a tendency for thrombosis development. Since, Behçet's disease (BD) is a systemic vasculitis, which is commonly complicated by arterial and venous thrombosis, we aimed to find out plasma TA... |
30,093 | Long-term follow-up of patients with suspected deep vein thrombosis of the upper extremity: survival, risk factors and post-thrombotic syndrome. | BACKGROUND: The outcome of upper extremity thrombosis in terms of morbidity, mortality and arm functionality is virtually unknown. We investigated mortality, risk factors, recurrent thrombosis and post-thrombotic syndrome (PTS) in patients with suspected upper extremity thrombosis. METHODS: Consecutive patients suspect... |
30,094 | A comparison of treatment combinations with and without radiotherapy for hepatocellular carcinoma with portal vein and/or inferior vena cava tumor thrombus. | To evaluate the potential role of external beam radiation therapy (EBRT) in the treatment of patients with hepatocellular carcinoma (HCC) who have portal vein (PV) and/or inferior vena cava (IVC) tumor thrombi.</AbstractText>One hundred fifty-eight patients with HCC who had PV and/or IVC tumor thrombus were reviewed an... |
30,095 | Ascites after orthotopic liver transplantation in children. | Ascites is a poorly understood postoperative complication of orthotopic liver transplantation (OLT). It is associated with additional morbidity and can prolong hospitalization considerably. The incidence, the factors predictive of occurrence and the etiology of this complication are not known. The charts of 118 patient... |
30,096 | Factor V Leiden, prothrombin 20210A and the risk of venous thrombosis among cancer patients. | Cancer patients have an increased risk of venous thrombosis (VT). The association of factor V Leiden (FVL) and the prothrombin 20210A variant with VT in cancer patients is not established. We genotyped 101 cancer patients with VT and 101 cancer patients without VT for these polymorphisms. Five cases and three controls ... |
30,097 | Management of thrombosis in cancer: primary prevention and secondary prophylaxis. | Although traditional anticoagulant regimens are highly effective and safe in most patients with venous thromboembolism (VTE), the aggressive natural history of VTE and the high risk of serious bleeding in cancer patients can complicate the management of VTE. In addition, because few clinical trials have focused on the ... |
30,098 | Duplex-Doppler ultrasonography in the detection of lower extremities deep venous thrombosis and in the detection of alternative findings. | The diagnoses observed in patients referred for the Doppler ultrasonographic examination of peripheral and iliac veins for suspected deep venous thrombosis (DVT) are presented in this study. During 48 months 2,610 patients were examined by duplex Doppler ultrasonography (US). Among these, 1,879 were women (72%) and 731... |
30,099 | Liver transplantation with simultaneous removal of an intracardiac transjugular intrahepatic portosystemic shunt and a vena cava filter without the utilization of cardiopulmonary bypass. | Transjugular intrahepatic shunts (TIPSs) are widely used in the management of portal hypertension complications including variceal bleeding, refractory ascites, and hepatic hydrothorax. Vena cava filters (VCFs) are an important therapeutic modality in the prevention of pulmonary emboli in patients suffering deep venous... |
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