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29,800 | Outpatient treatment of venous thromboembolism using low molecular weight heparins. An overview. | The development of low-molecular-weight heparins (LMWHs) was a significant advance in the treatment of venous thromboembolism (VTE). Their better bioavailability and more predictable anticoagulant activity than unfractionated heparin (UFH) allow subcutaneous administration without close laboratory monitoring, and thus ... |
29,801 | Retinal vein thrombosis as the presenting symptom of essential thrombocythemia. | Visual loss resulting from retinal vascular disorders can be the presenting sign of serious systemic disease. Associations between retinal vein thrombosis and other systemic disorders have been well documented, but a comprehensive literature search failed to reveal any report of essential thrombocythemia as a cause of ... |
29,802 | Enoxaparin for the prevention of venous thromboembolism associated with central vein catheter: a double-blind, placebo-controlled, randomized study in cancer patients. | The extent of venous thromboembolism (VTE) associated with central vein catheters (CVC) in cancer patients remains unclear. The aim of this study was to evaluate the efficacy and safety of the low molecular weight heparin, enoxaparin, in the prevention of VTE.</AbstractText>In a multicenter, double-blind study, consecu... |
29,803 | Randomized placebo-controlled study of low-dose warfarin for the prevention of central venous catheter-associated thrombosis in patients with cancer. | In this multicenter, randomized, placebo-controlled clinical trial, we studied whether warfarin 1 mg daily reduces the incidence of symptomatic central venous catheter (CVC) -associated thrombosis in patients with cancer.</AbstractText>Two hundred fifty-five patients with cancer who required a CVC for at least 7 days w... |
29,804 | Current trends in thrombolysis: implications for diagnostic and interventional radiology. | Current trends in thrombolysis are of relevance to both diagnostic and interventional radiologists. In addition to the traditional use of thrombolytic therapy in conditions such as peripheral arterial thrombosis, venous thrombosis and pulmonary embolic disease, more recent interest has focused on the potential use of t... |
29,805 | The safety profile of long-term, high-dose intraocular corticosteroid delivery. | To report the feasibility and safety profile of 2-mg and 6-mg fluocinolone acetonide implants after long-term follow-up in eyes with choroidal neovascularization (CNV).</AbstractText>Prospective, noncomparative, interventional case series of patients with non-age-related subfoveal choroidal neovascularization enrolled ... |
29,806 | Gender differences in deep venous thrombosis in a rat model: a preliminary study. | The purpose of this study was to determine whether gender differences have an effect on inflammation and thrombosis in a rat model of venous thrombosis. A thrombus was created in mature female (n = 12) and male (n = 12) Sprague Dawley rats (Rattus norvegicus) by ligating the inferior vena cava (IVC). The IVC containing... |
29,807 | Portal vein thrombosis following laparoscopic surgery in a patient with sickle cell disease. | We report a case of portal vein thrombosis following prolonged laparoscopic intervention in a patient with Sickle cell disease. The operation combined a laparoscopic splenectomy, cholecystectomy, appendectomy. Presentation was insidious with vague abdominal pain and persistent postoperative pyrexia. The literature is r... |
29,808 | Sonographic characterisation of hepatocellular carcinoma at time of diagnosis. | Hepatocellular carcinoma (HCC) is a malignant liver tumour with a high prevalence world-wide. For screening procedures conventional transabdominal B-mode ultrasound and AFP determination are commonly used. We investigated 100 consecutive patients with histologically proven hepatocellular carcinoma in order to evaluate ... |
29,809 | Immediate mobilisation in acute vein thrombosis reduces post-thrombotic syndrome. | To investigate the effect of compression and immediate ambulation in the acute stage of deep vein thrombosis (DVT) on the development of postthrombotic syndrome (PTS).</AbstractText>follow-up study of patients who previously have been enrolled in a randomized controlled trial.</AbstractText>outpatient department of a m... |
29,810 | Risk factors for venous thromboembolism in children. | The incidence of venous thromboembolism (VTE) is increasing in children as a result of therapeutic advances and improved clinical outcome in primary illnesses that previously caused mortality. VTE is mostly diagnosed in hospitalized children, especially sick newborns with central venous catheters and older children wit... |
29,811 | A feasibility study of continuing dose-reduced warfarin for invasive procedures in patients with high thromboembolic risk. | The management of perioperative anticoagulation therapy for patients having a high risk of thromboembolism who are receiving long-term oral anticoagulant therapy is uncertain. The prevalent approach is to discontinue oral anticoagulation therapy and initiate heparin therapy. Another potential strategy is to continue or... |
29,812 | Duplex ultrasound screening for deep vein thrombosis in Chinese after cesarean section. | To evaluate the incidence of asymptomatic deep vein thrombosis (DVT) in Chinese after cesarean section (CS).</AbstractText>This is a prospective observational study. Ethnic Chinese women who were asymptomatic for DVT and delivered by CS were included. Duplex ultrasound scan (US) of the lower limbs was carried out 3-7 d... |
29,813 | Superiority of thalidomide and dexamethasone over vincristine-doxorubicindexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma. | The aim of the present study was to compare thalidomide-dexamethasone (Thal-Dex) and vincristine-doxorubicin-dexamethasone (VAD) as primary therapy in preparation for autologous peripheral blood stem-cell (PBSC) transplantation for multiple myeloma (MM). For this purpose, we performed a retrospective matched case-contr... |
29,814 | Subarachnoid hemorrhage as the initial presentation of dural sinus thrombosis. | Cerebral venous thrombosis (CVT) can be difficult to diagnose because of its wide spectrum of clinical manifestations. Its diagnosis may be further complicated when patients initially present with acute subarachnoid hemorrhage (SAH). We report on four patients with SAH revealing a CVT and discuss the role of imaging fo... |
29,815 | Reversible MR imaging abnormalities following cerebral venous thrombosis. | Although rare, cerebral venous thrombosis (CVT) is being diagnosed more frequently owing to improved imaging techniques. The venous infarcts caused by CVT in 50% of patients are largely reversible and differ from arterial stroke. Our purpose was to study the time-dependent changes of venous infarcts on MR images and to... |
29,816 | The rise and fall of menopausal hormone therapy. | Clinical trials show that hormone therapy (HT) is an effective treatment for vasomotor symptoms and vaginal dryness. HT improves other symptoms including sleep and quality of life in women who have menopause symptoms. In the Women's Health Initiative controlled clinical trials, both estrogen therapy (ET) and estrogen p... |
29,817 | Mesenteric venous thrombosis in a patient with pancreatitis and protein C deficiency. | Mesenteric vein thrombosis is an uncommon manifestation of hypercoagulable states. A case is reported of superior mesenteric vein (SMV) thrombosis in a patient with pancreatitis and protein C deficiency. A discussion of SMV thrombosis identification, management, and outcomes is included. The patient presented with a si... |
29,818 | [Adequacy of prescribing the disaggregants in vascular pathology of the eye fundus and in primary open-angle glaucoma]. | The functional activity of blood platelets was studied in 936 patients with vascular pathology of the eye fundus (central chorioretinal dystrophy--CCRD; preproliferative diabetic retinopathy--PPDR; proliferative diabetic retinopathy--PDR; hypertensive retinopathy--HP; thrombosis of retinal veins--TRV; and primary open ... |
29,819 | Differential gene expression in hematopoietic progenitors from paroxysmal nocturnal hemoglobinuria patients reveals an apoptosis/immune response in 'normal' phenotype cells. | Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired stem cell disorder characterized clinically by intravascular hemolysis, venous thrombosis, and bone marrow failure. Despite elucidation of the biochemical and molecular defects in PNH, the pathophysiology of clonal expansion of glycosylphosphatidylinositol-anchor... |
29,820 | Raloxifene: results from the MORE study. | Raloxifene is the first Selective Estrogen Receptor Modulator (SERM) approved for the prevention and treatment of osteoporosis in postmenopausal women. Acting as an estrogen agonist in the skeleton and on lipid metabolism, raloxifene maintains bone mineral density (BMD) and prevents new vertebral fractures while improv... |
29,821 | Percutaneous salvage of a failing rex shunt. | Creation of a mesenterico-left portal vein (PV) shunt with use of autologous internal jugular vein (ie, Rex shunt) is a surgical option for the treatment of symptomatic extrahepatic PV occlusion. Herein a patient is described who underwent angioplasty and stent placement across a shunt stenosis by ultrasound (US)--guid... |
29,822 | Electronic alerts to prevent venous thromboembolism among hospitalized patients. | Prophylaxis against deep-vein thrombosis in hospitalized patients remains underused. We hypothesized that the use of a computer-alert program to encourage prophylaxis might reduce the frequency of deep-vein thrombosis among high-risk hospitalized patients.</AbstractText>We developed a computer program linked to the pat... |
29,823 | Outpatient treatment of venous thromboembolic disease based in an emergency department. | The efficacy, safety, and patient satisfaction of an emergency department (ED)-based outpatient program providing treatment for venous thromboembolic disease (VTD) were studied.</AbstractText>A prospective cohort study of patients enrolled in a hospital outpatient VTD treatment program was conducted from June 1999 to S... |
29,824 | Catheter management of occluded superior baffle after atrial switch procedures for transposition of great vessels. | We present successful catheter intervention in 4 patients with total occlusion of the superior baffle after an atrial switch procedure. A transseptal needle (in addition to the transhepatic route in 1 patient with known occluded femoral veins) was used to open the occluded segments and place stents. Additionally, we re... |
29,825 | Emerging strategies for treatment of venous thromboembolism. | Although considerable progress has been made in the treatment of venous thromboembolism (VTE), many unanswered questions remain, which are awaiting proper solution. Furthermore, new opportunities are emerging, which have the potential to rapidly change the therapeutic scenario. Selected patients with deep-vein thrombos... |
29,826 | [Diagnostic difficulties in primary mesothelioma]. | A 54-year-old woman with a history of fatigue and shortness of breath was found to have a pericardial effusion and mild mediastinal lymphadenopathy. Video-assisted pericardioscopy revealed thickened pericardium studded with multiple nodules. Histologically the tumor was diagnosed as papillary adenocarcinoma. The site o... |
29,827 | Issues in anticoagulant therapy: recent trials start to answer the tough questions. | Recent trials provide evidence to help guide the management of patients with recurrent episodes of venous thromboembolism, cancer patients with venous thromboembolism, and patients receiving anticoagulant therapy who must undergo surgery. |
29,828 | Axillary vein thrombosis as a manifestation of rapidly progressive neuropathic arthropathy of the shoulder associated with syringomyelia. | Neuropathic arthropathy is a destructive joint disease associated frequently with loss of proprioception. Syringomyelia (with or without Arnold-Chiari malformation) is characterized by slow progression over many years; the joints involved most frequently are the shoulders and elbows. Neuropathic arthropathy of the hand... |
29,829 | Vascular and nonvascular complications of renal transplants: sonographic evaluation and correlation with other imaging modalities, surgery, and pathology. | Cadaveric or living donor renal transplantation is commonly performed in individuals with end-stage renal disease. In recent years, gray-scale sonography, coupled with color Doppler sonography (CDUS), power Doppler sonography (PDUS), or spectral Doppler sonography, has become the primary imaging modality for these pati... |
29,830 | Cavernous sinus thrombosis elicited by a central retinal vein venous stasis retinopathy. | Central retinal vein occlusion is a relatively common retinal disorder in the elderly, and those with cardiovascular or thrombophilic risk factors are at increased risk. Although still unsatisfying, some treatments for the acute and chronic phases have been established based on randomized studies. However, for rare con... |
29,831 | Venous thromboembolism in colorectal cancer patients with central venous catheters for 5-FU infusion-based pharmacokinetic modulating chemotherapy. | Colorectal cancer patients with central venous catheters (CVC) for pharmacokinetic modulating chemotherapy (PMC) have a substantial risk of venous thromboembolism (VTE). PMC, designed as a hybrid of lower metronomic and higher shorter plasma 5-FU concentrations, has been clinically successful. To determine the effectiv... |
29,832 | Paroxysmal nocturnal hemoglobinuria and Budd-Chiari syndrome: therapeutic challenge with bone marrow transplantation, transjugular intrahepatic portosystemic shunt, and vena cava stent. | Stenosis of inferior vena cava can be a cause of or a consequence of Budd-Chiari syndrome (BCS). However, its occurrence after transjugular intrahepatic portosystemic shunt (TIPS) insertion has only been twice reported. We report the case of a 23-year-old man who presented BCS of the three suprahepatic veins. The cause... |
29,833 | An evaluation of rapid D-dimer assays for the exclusion of deep vein thrombosis. | We evaluated the performance of eight d-assays for the exclusion of deep vein thrombosis (DVT); Biopool AutoDimer, Biopool MiniQuant, bioMèrieux MDA D-Dimer, VIDAS, Dade Behring D-Dimer Plus, Trinity Biotech AMAX, NycoCard D-dimer and IL Test D-Dimer. The assays were evaluated both as stand-alone tests, and in com... |
29,834 | Deep vein thrombosis: a rare complication of thalidomide therapy in recurrent erythema nodosum leprosum. | A case of deep-vein thrombosis is reported in a female patient with multibacillary leprosy who received pulses of dexamethasone and cyclophosphamide for recurrent ENL that had not responded to prednisone and thalidomide. |
29,835 | Color-Doppler sonography in chronic venous insufficiency: what the radiologist should know. | Chronic venous insufficiency (CVI) is a pathologic condition caused by valvular incompetence, with or without associated venous outflow obstruction, which may affect both the superficial and the deep venous system, causing venous hypertension and stasis. The most common form of CVI is primary varicose veins due to the ... |
29,836 | [The aortocaval fistula, a rare complication of an aneurysm of the abdominal aorta]. | Four patients, 3 men aged 73, 60 and 81 years with hemodynamic instability and 1 man aged 80 with abdominal symptoms and breathlessness appeared to have an arteriovenous fistula secondary to spontaneous rupture of an atherosclerotic aneurysm: between the aorta and the V. cava inferior or between the A. and the left V. ... |
29,837 | [Thromboembolic and inflammatory complications of knee joint alloplasty with cemented endoprostheses]. | In the presented paper the authors evaluate the long-term results of treatment for inflammatory and thromboembolic complications in knee joint alloplasty with cemented endoprostheses. The clinical material spanning the years 1998-2003 are 15 patients with analysed complications, it determine 9% of all operated. They ha... |
29,838 | Treatment of deep vein thrombosis: what factors determine appropriate treatment? | To identify patients with deep vein thrombosis (DVT) for whom in-hospital treatment should be considered.</AbstractText>The literature was searched for studies on outpatient treatment of DVT. Seventeen studies were assessed: seven were randomized controlled trials (level I evidence), and 10 were non-randomized trials (... |
29,839 | [Treatment of intestinal failure by total parenteral nutrition at home in children and adults]. | Intestinal failure is characterised by inability of the intestine to absorb sufficient nutrients to maintain the integrity and function of the body. This can be caused by malabsorption due to too short an intestine or an abnormality of the mucosa, or by a severe motility disorder. In addition to dietary measures, the p... |
29,840 | A clinician's review of the WHI-related literature. | When the monitoring board of the Women's Health Initiative (WHI) canceled the estrogen-progestin arm of the study in July 2002, the effect was immediate and dramatic, as several million postmenopausal women with the full agreement of their physicians ceased taking combined hormone therapy. Soon thereafter the manufactu... |
29,841 | The efficacy of intravitreal triamcinolone acetonide on macular edema in branch retinal vein occlusion. | To evaluate the effectiveness of intravitreal triamcinolone acetonide as primary treatment of macular edema in branch retinal vein occlusion.</AbstractText>Fifteen eyes of 15 patients with macular edema due to branch retinal vein occlusion (Group 1) who received 8 mg/0.2 ml of intravitreal triamcinolone injection as pr... |
29,842 | Dalteparin: new indication. Prophylaxis in medical patients: no advance. | (1) Heparin prophylaxis for medical inpatients who are confined to bed is controversial, because there are no reliable comparative data. Prophylaxis only seems justified for some patients at high risk of pulmonary embolism who have no risk factors for bleeding. (2) The licence of dalteparin, a low-molecular-weight hepa... |
29,843 | Ischemic stroke in children treated for acute lymphoblastic leukemia: a retrospective study. | The clinical and diagnostic findings and the factors influencing the neurologic and radiologic outcome of symptomatic ischemic stroke were evaluated in a group of 2,318 children with acute lymphoblastic leukemia (ALL) treated according to the AIEOP (Italian Association of Pediatric Hematology and Oncology) study protoc... |
29,844 | Leg perforator vein incompetence: functional anatomy. | To retrospectively determine the anatomic patterns of reflux of incompetent perforator veins (IPVs) at the sites of their highest prevalence in relation to the anatomic distribution of valvular incompetence in the veins of the calf and thigh, with emphasis on the deep system, across the clinical spectrum of chronic ven... |
29,845 | Mutation of the prothrombin gene and thrombotic events in patients with polycythemia vera or essential thrombocythemia: a cohort study. | The association between a prothrombin mutation and the risk of thrombosis was analyzed in 214 patients with polycythemia vera or essential thrombocythemia. The rate for venous thrombotic events was 14.7/100 patient-years in patients with the prothrombin mutation compared to 0.8 in patients without the mutation (rate ra... |
29,846 | Antiphospholipid antibodies associated with recurrent pregnancy loss: prospective, multicenter, controlled pilot study comparing treatment with low-molecular-weight heparin versus unfractionated heparin. | To evaluate the use of low-molecular-weight heparin (LMWH) in combination with low-dose aspirin (LDA) for the treatment of antiphospholipid antibody (APA)-associated recurrent pregnancy loss and to compare the results with the use of unfractionated heparin (UFH) plus LDA.</AbstractText>Prospective, controlled, multicen... |
29,847 | Cerebral venous thrombosis in a gentleman presenting with fever, convulsion and frontotemporal haemorrhages. | Cerebral venous thrombosis (CVT) is an uncommon but serious type of stroke. Thrombosis may involve the cortical or deep veins or the venous sinuses. The presenting clinical features are non-specific. We report a 48-year-old man with CVT who presented with fever, bitemporal throbbing headache, and generalised convulsion... |
29,848 | Acute pulmonary embolism in elderly: clinical characteristics and outcome. | To evaluate the clinical characteristics and outcome of acute pulmonary embolism in elderly in comparison to the younger patients.</AbstractText>Study population consisted of 136 patients with a confirmed diagnosis of acute pulmonary embolism. Clinical characteristics and thromboembolic risk factors were analyzed betwe... |
29,849 | Diagnosis accuracy of a new challenger for thrombosis exclusion, the Stratus CS DDMR. | The diagnostic accuracy of a new Point of Care, rapid and quantitative D-dimer assay (Stratus CS DDMR from Dade Behring) was evaluated.</AbstractText>Vidas test from bioMerieux was used as reference method in 279 patients recruited from a management study in progress in our institution.</AbstractText>Both assays show c... |
29,850 | Platelets adhered to endothelial cell-bound ultra-large von Willebrand factor strings support leukocyte tethering and rolling under high shear stress. | Leukocyte rolling on vascular endothelium is mediated by an interaction between P-selectin expressed on endothelial cells and P-selectin glycoprotein ligand-1 on leukocytes. This interaction reduces the velocity of leukocyte movements to allow subsequent firm adhesion and transmigration. However, the interaction has so... |
29,851 | In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939--an oral, direct Factor Xa inhibitor. | BAY 59-7939 is an oral, direct Factor Xa (FXa) inhibitor in development for the prevention and treatment of arterial and venous thrombosis. BAY 59-7939 competitively inhibits human FXa (K(i) 0.4 nm) with > 10 000-fold greater selectivity than for other serine proteases; it also inhibited prothrombinase activity (IC(... |
29,852 | The incidence and prognostic significance of elevated cardiac troponins in patients with submassive pulmonary embolism. | Although the incidence and prognostic significance of elevated cardiac troponins are known in patients with massive pulmonary embolism (PE), few studies have addressed this issue in patients with hemodynamically stable, submassive PE, who comprise the majority of patients presenting with PE. This prospective cohort stu... |
29,853 | Primary and secondary prophylaxis of venous thromboembolism with low-molecular-weight heparins: prolonged thromboprophylaxis, an alternative to vitamin K antagonists. | Low-molecular-weight heparins (LMWHs) are used widely in the treatment and prevention of venous thromboembolism (VTE). The LMWHs dalteparin and enoxaparin reduce the rate of VTE by at least 50% if administered for 4-5 weeks following major orthopedic surgery, compared with in-hospital prophylaxis for 7-15 days. Meta-an... |
29,854 | Risk of a first venous thrombotic event in carriers of a familial thrombophilic defect. The European Prospective Cohort on Thrombophilia (EPCOT). | Reliable risk estimates for venous thrombosis in families with inherited thrombophilia are scarce but necessary for determining optimal screening and treatment policies.</AbstractText>In the present analysis, we determined the risk of a first venous thrombotic event in carriers of a thrombophilic defect (i.e. antithrom... |
29,855 | Megakaryocytes endocytose and subsequently modify human factor V in vivo to form the entire pool of a unique platelet-derived cofactor. | Factor Va (FVa), derived from plasma or released from stimulated platelets, is the essential cofactor in thrombin production catalyzed by the prothrombinase complex. Plasma-derived factor V (FV) is synthesized in the liver. The source(s) of the platelet-derived cofactor remains in question. We identified a patient homo... |
29,856 | [Intraoperative transesophageal echocardiography to guide removal of a hypernephroma with vena cava and right atrial extension]. | We describe the case of a 70-year-old man who underwent resection of a right hypernephroma with vena caval and right atrial extension with continuous monitoring by transesophageal echocardiography. The monitoring technique brought important advantages, providing images that facilitated anatomical and functional evaluat... |
29,857 | [Anesthesia for scoliosis surgery: preoperative assessment and risk screening of patients undergoing surgery to correct spinal deformity]. | Spinal column deformity is associated with potentially serious alterations of respiratory and cardiac function. Such alterations, in association with the underlying disease that caused the deformity--such as neuromuscular disease--are risk factors that affect the prognosis for scoliosis patients undergoing anesthesia a... |
29,858 | Hypercoagulability affecting early vein graft patency does not exist after off-pump coronary artery bypass. | Hypercoagulability may compromise the patency of bypass grafts. The authors hypothesized that perioperative in vitro platelet responses to varying agonists (eg, thrombin, platelet activating factor, collagen, adenosine diphosphate) correlate with early graft thrombosis after off-pump coronary artery bypass grafting (OP... |
29,859 | [Effects of Pingyangmycin albumin microspheres on sclerostenosis of the rabbit central auricular arteries]. | The aim of this study was to investigate the mechanism of Pingyangmycin-albumin microspheres (PYM-AMS) acted on the rabbit central auricular arteries.</AbstractText>In the study of randomized block design, 24 Japanese white rabbits were divided into 4 groups, 6 rabbits in each group. The animals were put on the operati... |
29,860 | Superior vena cava (SVC) thrombosis: diagnosis and follow up by transesophageal echocardiography (TEE). | Hemodialysis catheters (HC) were developed as a vascular access, intended to be a bridging device until a permanent access is placed. Although many reports exist of indwelling catheter-related thrombosis, optimal diagnostic study and therapeutic options are yet to be established. We are presenting a case with HC thromb... |
29,861 | Neuroimaging of cerebral venous thrombosis. | Early and accurate diagnosis of cerebral venous thrombosis (CVT) is possible with the help of computed tomography (CT) scan and magnetic resonance imaging (MRI). Empty delta sign on postcontrast CT is present in only up to 30% of the cases. The role of CT venography is not yet established, but it is emerging as an effe... |
29,862 | New method for the detection of thrombus formation in cardiovascular devices: optical sensor evaluation in a flow chamber model. | We proposed a new method of detecting the onset of thrombus formation based upon the backscattered light intensity changes caused by the alteration of blood flow behavior in the cardiopulmonary devices. In an optical senor based upon the First Order Scattering theory, the relationship between the backscattered light in... |
29,863 | Risk factors for thromboembolic complications in inflammatory bowel disease: the role of hyperhomocysteinaemia. | Inflammatory bowel disease (IBD) is associated with an increased risk for thromboembolic events. Aim of this study was to examine the relationship of hyperhomocysteinemia and thrombosis in IBD patients and to assess the role of this factor in addition to other known prothrombotic abnormalities. IBD patients with a hist... |
29,864 | Salvage operations of free tissue transfer following internal jugular venous thrombosis: a review of 4 cases. | The internal jugular vein (IJV) is used as the optimal recipient for free-tissue transfer in reconstruction following modified radical neck dissection. Some reports documented rare cases of flap compromise following IJV thrombosis, but large sample studies are few. We present cases of emergent exploration and an analys... |
29,865 | Venous thromboembolism prophylaxis: role of factor xa inhibition by fondaparinux. | Fondaparinux (Arixtra, GlaxoSmithKline, Philadelphia, PA.) is the first synthetic selective factor Xa inhibitor. A worldwide phase III program, that consists of four randomized, double-blind trials, in patients who underwent surgery for hip fracture, and elective hip replacement and elective major knee surgery was cond... |
29,866 | Role of race and sex in diagnosis and one-year follow up of deep venous thrombosis. | This study examines the role of sex and race in the diagnosis and outcome of deep vein thrombosis (DVT). A retrospective study was performed of 632 patients who underwent venous duplex ultrasound from August 1998 to July 1999. Comparisons were made by Chi-square analysis. Seventy-four percent of the patients were women... |
29,867 | Drotrecogin alfa (activated, Xigris) in combination with heparin or melagatran: an in vitro investigation. | The present in vitro study of human plasma investigated the anticoagulant effects of recombinant human activated protein C (rhAPC; drotrecogin alfa [activated, Xigris]), combined with either unfractionated heparin (UH) or the direct thrombin inhibitor melagatran.</AbstractText>Prolongation of clotting time and generati... |
29,868 | Angiographic findings in arteriovenous dissection (sheathotomy) for decompression of branch retinal vein occlusion. | Arteriovenous dissection (sheathotomy) is a new therapeutic option in patients with branch retinal vein occlusion (BRVO) and macular involvement. We present an angiographic follow-up of 22 patients who underwent arteriovenous dissection (AVD).</AbstractText>Twenty-two patients (15 women; mean age 68.7+/-8.0 years) were... |
29,869 | Bilateral retinal venous occlusion in pigmentary glaucoma. | The association of central retinal vein occlusion with primary open angle glaucoma is well known. This communication reports the occurrence of branch retinal vein occlusion and central retinal vein occlusion in a case of pigmentary glaucoma.</AbstractText>A 32-year-old man presented with old branch retinal vein occlusi... |
29,870 | Thalidomide in combination with dexamethasone for pretreated patients with multiple myeloma: serum level of soluble interleukin-2 receptor as a predictive factor for response rate and for survival. | The aim of this study was to assess the side effects and the efficacy of thalidomide alone or in combination with dexamethasone in relapsed multiple myeloma (MM) and to evaluate possible predictive factors for response rate and survival. Twenty-nine pretreated patients were enrolled, including 13 patients with a relaps... |
29,871 | [Hepatocellular carcinoma with cardiovascular invasion. Report of five cases]. | The diagnosis of hepatocellular carcinoma in cirrhotic patients has increased, mainly due to early detection using newer imaging techniques. The therapeutic approach depends on the tumor staging and the liver function. Cardiac involvement has a very bad prognosis. We report three males aged 59, 75 and 76 years and two ... |
29,872 | Inflammation in patients with lupus anticoagulant and implications for thrombosis. | The underlying mechanism of the prothrombotic state associated with the lupus anticoagulant (LAC) has not been fully elucidated. Evidence suggests involvement of inflammation in arterial and venous thrombosis, and it may be hypothesized that subclinical inflammation aggravates the tendency to thrombosis in patients wit... |
29,873 | Extradural hematoma causing venous sinus obstruction and pseudotumor cerebri syndrome. | The case of a small right occipital extradural hematoma in a 10-year-old girl is presented. The patient had bifrontal occipital headache out of proportion to the size of the hematoma, as well as diplopia. MR venography revealed compression and occlusion of the dominant right transverse sinus resulting in a pseudotumor ... |
29,874 | Venous disorders: overview of current practice. | Venous disease often is overlooked until the problems it causes become severe. When patients present with concomitant diseases or disorders, those disorders may take priority both in the patient's mind and the caregiver's. Fortunately, there has been an increasing interest in the diagnoses and treatment of venous disor... |
29,875 | Diagnosis and management of iliac vein compression syndrome. | Iliac vein compression syndrome (IVCS) is the most probable cause of iliofemoral deep venous thrombosis (DVT). One half to two thirds of patients with left-sided iliofemoral DVT have intraluminal webs or spurs from chronic extrinsic compression of the left iliac vein at the crossing point of the right common iliac arte... |
29,876 | Characterization of molecular defect of 13387-9delG mutated antithrombin in inherited type I antithrombin deficiency. | As a major physiological inhibitor of thrombin and other coagulation proteases, antithrombin (AT) plays an important role in the maintenance of normal hemostasis and its deficiency is associated with a predisposition for familial venous thromboembolic disease. Recently, we found a novel mutation (13387-9delG) in the an... |
29,877 | Stroke induced by splenectomy in hemoglobin Madrid: autopsy clues to the underlying mechanism. | Thrombo-embolic events, which can be increased after splenectomy in hemoglobin disorders, can cause potentially lethal complications. Although venous thrombosis has been reported, arterial strokes are rarely reported. A case of stroke in a 52-year-old patient with a previously performed splenectomy for known hemoglobin... |
29,878 | Protein S type III deficiency is no risk factor for venous and arterial thromboembolism in 168 thrombophilic families: a retrospective study. | Free protein S rather than total protein S levels are currently measured to detect inherited protein S deficiency. Because type III (free protein S) deficiency is still not established as risk factor for thrombosis, we assessed the absolute risk of venous and arterial thromboembolism in a family cohort study. Annual in... |
29,879 | Staggered bilateral total knee arthroplasty performed four to seven days apart during a single hospitalization. | The purpose of this study was to evaluate the types and prevalence of complications associated with bilateral total knee replacement performed four to seven days apart during a single hospitalization and to compare them with those associated with bilateral knee replacement performed sequentially under the same anesthet... |
29,880 | Evaluation and management of pain in patients with Klippel-Trenaunay syndrome: a review. | Klippel-Trenaunay syndrome (KTS) is a rare disorder that consists of a triad of capillary vascular malformation, venous malformations and/or varicose veins, and soft tissue and/or bony hypertrophy. Pain is a real and debilitating problem in these patients. We have observed 9 common causes of pain in KTS: (1) chronic ve... |
29,881 | Severe Staphylococcal sepsis in adolescents in the era of community-acquired methicillin-resistant Staphylococcus aureus. | More than 70% of the community-acquired (CA) staphylococcal infections treated at Texas Children's Hospital are caused by methicillin-resistant Staphylococcus aureus (MRSA). Since September 2002, an increase in the number of severely ill patients with S aureus infections has occurred. This study provides a clinical des... |
29,882 | Outflow block secondary to stenosis of the inferior vena cava following living-donor liver transplantation? | Although it is well known that outflow block is caused by stenosis or occlusion of hepatic vein anastomoses following living donor liver transplantation (LDLT), there have been few reports on inferior vena cava (IVC) stenosis following LDLT. In this paper, we report two cases of IVC stenosis and hepatic vein outflow bl... |
29,883 | Evolution of management for Budd-Chiari syndrome: a team's view from 2564 patients. | Exploring the development of therapy for a formerly rare and life-threatening disorder, Budd-Chiari syndrome (BCS).</AbstractText>From 1981 to 2003, 2677 patients with BCS were admitted including 2546 cases that underwent intervention. Therapeutic means included 170 membranotomies, 181 cavoatrial shunts, 312 mesoatrial... |
29,884 | Laparoscopic live donor nephrectomy. | The demand for renal transplants is greater than the available kidneys. Live donation is one way of increasing the supply. Laparoscopic removal of the donor kidney appears to reduce morbidity for the donors. Some who are hesitant because of the morbidity associated with open nephrectomy are willing to consider the lapa... |
29,885 | Deep venous thrombosis and pulmonary embolism following physical restraint. | We describe a case of deep venous thrombosis (DVT) and pulmonary embolism (PE) following the use of physical restraint in a patient with a diagnosis of acute delusional psychotic disorder.</AbstractText>A new case report of DVT and PE associated with prolonged physical restraint is presented. The literature on physical... |
29,886 | Use of the Solis cage and local autologous bone graft for anterior cervical discectomy and fusion: early technical experience. | The authors prospectively evaluated the clinical and radiological outcomes after anterior cervical discectomy and fusion (ACDF) involving placement of a Solis cage and local autograft in patients who presented with symptomatic cervical spondylosis.</AbstractText>Twenty-two consecutive patients underwent ACDF for radicu... |
29,887 | Plasma homocysteine is a risk factor for recurrent vascular events in young patients with an ischaemic stroke or TIA. | Young patients with an ischaemic stroke or transient ischaemic attack (TIA) often have no vascular risk factors. Hyper-homocysteinaemia is an established risk factor for stroke in elderly patients but it is uncertain whether it is also important for the prognosis of young ischaemic stroke and TIA patients. We examined ... |
29,888 | [Superficial thrombophlebitis in non varicose veins of the lower limbs. A prospective analysis in 42 patients]. | Recent publications allow better understanding of superficial thrombophlebitis (ST) of the lower limb veins. However ST occurring in non varicose veins (NVV) and those occurring in varicose veins (VV) are seldom distinguished in literature.</AbstractText>1) To estimate the potential gravity of ST occurring in NVV by pu... |
29,889 | [Drug addiction and cardiovascular pathologies].<Pagination><StartPage>243</StartPage><EndPage>248</EndPage><MedlinePgn>243-8</MedlinePgn></Pagination><Abstract><AbstractText>Drug addiction which entails cardiovascular risks unknown or misknown to physicians, currently involves an increasing number of miscellaneous dru... | Drug addiction which entails cardiovascular risks unknown or misknown to physicians, currently involves an increasing number of miscellaneous drugs, existing in manifold forms. There appears to be no bounds on the way of intake. All territories of the body may be affected with more or less severity. In young people, th... |
29,890 | Effect of docetaxel in patients with hormone-dependent prostate-specific antigen progression after local therapy for prostate cancer. | To evaluate docetaxel in the treatment of patients with early-stage prostate cancer with prostate-specific antigen (PSA) progression after local therapy without androgen ablation therapy.</AbstractText>Twenty-five patients with adenocarcinoma of the prostate with PSA progression despite local therapy were treated with ... |
29,891 | Transaminitis after pancreatic islet transplantation. | An asymptomatic, self-limited transaminitis uniformly follows pancreatic islet transplantation (PIT) performed through portal vein (PV) infusion. The underlying cause and significance of this transaminitis is unclear.</AbstractText>Records of all patients with insulin-dependent diabetes mellitus who had undergone PIT a... |
29,892 | Thromboprophylaxis in pelvic and acetabular trauma surgery. The role of early treatment with low-molecular-weight heparin. | We prospectively studied the outcome of a protocol of prophylaxis for deep vein thrombosis (DVT) in 103 consecutive patients undergoing surgical stabilisation of pelvic and acetabular fractures. Low-molecular-weight heparin (LMWH) was administered within 24 hours of injury or on achieving haemodynamic stability. Patien... |
29,893 | Evaluation of thrombotic children with malignancy. | The purpose of this study was to evaluate inherited and acquired prothrombotic risk factors among children with malignancies who have thrombosis and emphasize the importance of inherited prothrombotic risk factors. Thirty-seven consecutive children with thrombosis and malignancy were included in this study. The patient... |
29,894 | "ProC Global": a functional screening test that predicts recurrent venous thromboembolism. | Abnormalities of the Protein C (PC) pathway are found in the majority of patients with thrombophilia. ProC Global is a coagulation assay that reflects the net effect of the PC pathway by measuring the activated partial thromboplastin time (APTT) of patient and control plasma, before and after activation of endogenous P... |
29,895 | Cost-effectiveness of low-molecular-weight heparin for secondary prophylaxis of cancer-related venous thromboembolism. | Although extended secondary prophylaxis with low-molecular-weight heparin was recently shown to be more effective than warfarin for cancer-related venous thromboembolism, its cost-effectiveness compared to traditional prophylaxis with warfarin is uncertain. We built a decision analytic model to evaluate the clinical an... |
29,896 | Post-thrombotic syndrome, functional disability and quality of life after upper extremity deep venous thrombosis in adults. | The post-thrombotic syndrome (PTS) after upper extremity deep venous thrombosis (UEDVT) has not been well characterized. The objective of our study was to describe and quantify residual symptoms, functional disability and quality of life associated with PTS after UEDVT in adults. Twenty-four patients with objectively d... |
29,897 | Risk factors associated with symptomatic pulmonary embolism in a large cohort of deep vein thrombosis patients. | In patients with deep vein thrombosis (DVT), the factors which predispose to concomitant symptomatic pulmonary embolism (PE) have remained uncertain. From a prospective cohort of 5,451 consecutive patients with ultrasound-confirmed DVT, we analyzed 4,211 patients with a known status for presence (n=639) or absence (n=3... |
29,898 | Basal high-sensitivity-C-reactive protein levels in patients with spontaneous venous thromboembolism. | The role of C-reactive protein (CRP) in venous thromboembolism (VTE) is still under discussion because of controversial results in the literature. Conflicting data may have partly been due to bias by exogenous factors altering CRP levels. We investigated CRP concentrations in patients with spontaneous VTE applying a st... |
29,899 | The ABO blood group genotype and factor VIII levels as independent risk factors for venous thromboembolism. | Factor VIII (FVIII), von Willebrand factor (vWF) and the ABO blood groups have been associated with thrombosis. The ABO locus has functional effects on vWF and FVIII levels and is genetically correlated with FVIII, vWF and thrombosis. We carried out a case-control study to assess the role of FVIII, vWF and ABO types on... |
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