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31,000 | Evaluation and management of the cardiovascular patient embarking on air travel. | Almost 2 billion passengers embark on international and domestic air travel each year. An increasing number of travelers will have cardiovascular disease as the population continues to age and our ability to treat cardiac disease improves. Guidelines for safe air travel in this population vary and are supported by few ... |
31,001 | The impact of venous thrombosis on quality of life. | Quality of life (QOL) is increasingly seen as an important outcome in clinical care. Etiology, diagnosis, and management of venous thrombosis have been studied extensively, but only few studies have examined the impact of venous thrombosis on quality of life. The purpose of this study was to examine the impact of venou... |
31,002 | What's new in vascular ultrasound. | Duplex ultrasound has long been the method of choice in the diagnosis and evaluation of deep venous thrombosis and carotid artery stenosis and in monitoring lower extremity bypasses. In recent years, innovative procedures and technology have fostered new applications for duplex ultrasound, such as detection of in-stent... |
31,003 | Small change in capnography led to the detection of an intravascular thrombus. | This report highlights the importance of accurate interpretation of even small intraoperative capnography changes. In this case, an otherwise unexplained sudden small decrease in end-expiratory carbon dioxide tension (P(ET)CO2) led to the detection of a deep venous thrombus. During the surgery of a 34-year-old woman wi... |
31,004 | The role of timing of tourniquet release and cementing on perioperative blood loss in total knee replacement. | The purpose of our study is to estimate the effect of tourniquet release and cementing in perioperative blood loss associated with total knee arthroplasty. Eighty patients were randomly allocated into two equal groups concerning the timing of tourniquet release. Group A: patients with tourniquet release and haemostasis... |
31,005 | Hypercoagulable states in patients with hepatocellular carcinoma. | Hepatocellular carcinoma (HCC) patients have an increased risk for venous thromboembolism, mainly portal venous thrombosis (PVT). The aim of this study was to assess the role of acquired and hereditary thrombotic risk factors in HCC patients. Thirty-one patients with HCC, 30 patients with cirrhosis but without HCC or P... |
31,006 | Combined computed tomography venography and pulmonary angiography for the diagnosis PE and DVT in the ED. | The purpose of this study is to evaluate the usefulness of combined computed tomography venography and pulmonary angiography (CTVPA) in the diagnosis of venous thromboembolic (VTE) disease in the emergency department (ED). CTVPA images and clinical data of 73 nonselected patients with suspected pulmonary embolism (PE) ... |
31,007 | Bilateral central retinal vein occlusion associated with multiple myeloma. | To report a case of simultaneous bilateral central retinal vein occlusion (CRVO) associated with multiple myeloma.</AbstractText>A 65-year-old woman had sudden, painless loss of vision in both eyes for 20 days. Ophthalmologic examination revealed bilateral CRVO. Appropriate medical workup was conducted, and multiple my... |
31,008 | Do hemorheological alterations play any role in the development of thrombotic events in Behçet's disease? | Behçet's disease (BD) is associated with an increased thrombotic risk, although the prothrombotic mechanisms are not clearly defined. Alterations in blood rheology, specially increased erythrocyte aggregation has been suggested to play an important role in the development of thrombotic events in patients with Beh&... |
31,009 | Raised intracranial pressure presenting with spontaneous periorbital bruising: two case reports. | The venous drainage of the orbit is known to be via the ophthalmic and vortex veins which communicate with the cavernous sinus. We describe two patients with raised intracranial pressure presenting with periorbital bruising. In one patient dural venous sinus thrombosis was demonstrated and it is suspected that the caus... |
31,010 | First-line therapy with thalidomide and dexamethasone in preparation for autologous stem cell transplantation for multiple myeloma. | The marked synergy of thalidomide and dexamethasone in advanced and refractory multiple myeloma (MM) provided the basis for a phase 2 clinical study aimed at investigating the efficacy and toxicity of this combination as first-line therapy for patients less than 65 years old with newly diagnosed disease.</AbstractText>... |
31,011 | Stroke following variceal sclerotherapy. | Paradoxical embolism via a patent foramen ovale (PFO) has been identified as a potential risk factor for ischaemic stroke. Such occurrences are associated with risk factors for deep vein thrombosis (DVT), e. g. pregnancy, immobilisation, and surgery of the lower limbs.</AbstractText>A 54-year-old otherwise healthy fema... |
31,012 | Intraindividual consistency of the activated protein C resistance phenotype. | Resistance to activated protein C (APC) has been demonstrated to be a risk factor for venous thromboembolism, but it is not known whether this phenotype is consistent over time. We reinvestigated 2580 subjects from the Vicenza Thrombophilia and Atherosclerosis (VITA) Project to evaluate the prevalence of a consistent A... |
31,013 | [Cerebral venous thrombosis as the presenting symptom of systemic lupus erythematosus]. | Cerebral venous thrombosis (CVT) is an infrequent process in systemic lupus erythematosus. We report the case of a female patient whose initial manifestation of lupus was a CVT.</AbstractText>A 30-year-old female who presented headaches and diminished visual acuity; on exploring the patient bilateral papilloedema was f... |
31,014 | Case of Lemierre's syndrome presenting with thyroid abscess. | Lemierre's syndrome is an uncommon condition characterized by post-anginal septicemia due to anaerobes. Reported here is a case of Lemierre's syndrome presenting with thyroid and liver abscesses. At presentation, the 70-year-old female patient complained of fever, jaundice and neck pain. Computed tomography (CT) and ul... |
31,015 | Predicting the risk of recurrence of venous thromboembolism. | Although several clinical studies have investigated the effects of different treatment periods in subjects after a VTE event, the optimal duration of oral anticoagulation is still uncertain. Our review focused on studies that evaluated different risk factors that might be useful to stratify patients into categories at ... |
31,016 | Antithrombotic therapy and cancer. | To assess the current evidence from recent clinical trials investigating antithrombotic agents for the prophylaxis and treatment of venous thromboembolism in cancer patients and for the effects of these agents on cancer progression.</AbstractText>A growing body of evidence supports the preventive use of antithrombotic ... |
31,017 | Appropriate level and length of postthrombotic warfarin treatment: an evaluation of recent developments. | Current treatment and secondary prophylaxis of venous thromboembolism has two major drawbacks. During vitamin K antagonist therapy, patients need to be monitored closely to maintain efficacy and minimize the bleeding risk due to fluctuations of the prothrombin time (international normalized ratio, INR), and after cessa... |
31,018 | Factor V Leiden: a disorder of factor V anticoagulant function. | Activated protein C (APC) resistance, which is often associated with the factor V R506Q (FV Leiden) mutation, is a common risk factor for venous thrombosis. Study of the mechanism of APC resistance has revealed that coagulation FV stimulates the APC-catalysed inactivation of FVIIIa, and that this anticoagulant function... |
31,019 | Antiphospholipid antibodies: update on detection, pathophysiology, and treatment. | The antiphospholipid syndrome is a noninflammatory disease characterized by the presence of antiphospholipid antibodies in the plasma of patients with venous or arterial thrombosis or obstetric complications. Understanding of the pathology of the syndrome is only rudimentary and no physician can pretend that treatment ... |
31,020 | Catastrophic secondary antiphospholipid syndrome with peripheral nervous system involvement: a case report. | A 34-year-old woman was admitted to our emergency room with a high fever, abdominal pain, dyspnea and confusion. High fever and abdominal pain had first occured after a cystocele operation 5 months earlier. Later, congestive heart failure with mural thrombus formation, peripheral polyneuropathy and ischemic cerebrovasc... |
31,021 | Deep vein thrombosis associated with distension of the urinary bladder due to benign prostatic hypertrophy--a case report. | A 76-year-old man was admitted with a first episode of deep vein thrombosis (DVT) of his left leg. It was associated with a distended urinary bladder, due to benign prostatic hypertrophy. Screening for malignancy was negative. Laboratory testing revealed protein S deficiency. Although a distended bladder may induce ven... |
31,022 | Clinical guidelines online: do they improve compliance? | The introduction of intranet services in a district general hospital provided an opportunity to put evidence based national guidelines online to facilitate access and promote application of best practice in acute medical care. This study evaluated the effectiveness of this approach.</AbstractText>Local guidelines were ... |
31,023 | Mannose-binding lectin variant alleles and the risk of arterial thrombosis in systemic lupus erythematosus. | Cardiovascular disease is an important complication in patients with systemic lupus erythematosus (SLE). Variant alleles of the mannose-binding lectin gene are associated with SLE as well as with severe atherosclerosis. We determined whether mannose-binding lectin variant alleles were associated with an increased risk ... |
31,024 | Lemierre's syndrome associated with septic pulmonary embolism: a case report. | An 18-year-old female patient suffering from a painful right-sided neck mass was admitted to our emergency service. Computed tomography of the neck revealed thrombosis of the right internal jugular vein. Computed tomography of the chest indicated septic pulmonary emboli in both lungs. Blood and oropharyngeal cultures s... |
31,025 | A case of warfarin skin necrosis despite enoxaparin anticoagulation in a patient with protein S deficiency. | Warfarin-induced skin necrosis is a rare complication associated with the use of oral anticoagulants. Most patients develop this at the initiation of therapy, often while still receiving intravenous unfractionated heparin (UFH). Recently, low-molecular-weight heparins (LMWHs) have gained wider use, providing an option ... |
31,026 | Great saphenous vein leiomyosarcoma: a rare malignant tumor of the extremity--two case reports. | Peripheral vascular leiomyosarcomas are rare. Two cases of intramural leiomyosarcomas of the great saphenous vein are described. The first case is considered a high-grade sarcoma, based on the high mitotic index on histologic study. The second case presents only infrequent mitoses on light microscopy. Immunohistochemic... |
31,027 | Endovascular management of iliac vein occlusive disease. | Iliac vein occlusive disease presents with either acute or chronic symptoms, both of which can be managed with endovascular techniques. This report summarizes our experience in a small cohort of patients undergoing percutaneous treatment of iliac vein occlusive disease. Six women and one man with occlusive lesions in t... |
31,028 | Saphenous vein loop to femoral artery arteriovenous fistula: a practical alternative. | Secondary to central venous stenosis or thrombosis, alternate sites for permanent hemodialysis need to be explored. The authors' experience with the greater saphenous vein to common femoral artery loop arteriovenous fistula (GSV-CFA AVF) is presented. A retrospective review was performed of 4 women and 3 men with a mea... |
31,029 | Surveillance venous duplex is not clinically useful after total joint arthroplasty when effective deep venous thrombosis prophylaxis is used. | The early detection of deep venous thrombosis (DVT) and treatment with systemic anticoagulation to prevent pulmonary embolism (PE) are essential in the management of patients undergoing total joint arthroplasty (TJA). However, improvements in prophylactic measures have significantly decreased the occurrence of DVT in t... |
31,030 | Dissociative anesthesia for safety's sake: ketamine and diazepam--a 35-year personal experience. | Recent discussions and proposed rules and regulations regarding outpatient surgery facilities have raised the question of the appropriateness of general anesthesia versus heavy sedation. The controversy is based mostly on anecdotal information and the prejudice of the authors. A recent article that describes the improv... |
31,031 | Upper extremity deep venous thrombosis: interventional management. | Upper extremity deep venous thrombosis, previously thought to be a relatively innocuous disorder in comparison to lower extremity deep venous thrombosis, has recently begun to receive the attention it merits. Its optimal management remains controversial despite the development of several new techniques and devices whic... |
31,032 | Mechanical thrombectomy for DVT. | Deep venous thrombosis is a common source of morbidity and mortality in the United States. Complications include pulmonary embolism and chronic post-thrombotic syndrome. Chronic post-thrombotic syndrome is characterized by extremity pain, edema, venous claudication, skin changes, and skin ulceration. This syndrome is a... |
31,033 | Thrombolysis for lower extremity deep venous thrombosis. | Catheter-directed thrombolysis (CDT) has been proposed as an alternative mode of therapy to anticoagulation in patients with massive, symptomatic deep vein thrombosis of the extremity. The major goal of therapy is to rapidly restore venous blood flow, reduce the pain and edema of the extremity, preserve venous valve fu... |
31,034 | Medical management of venous thromboembolic disease. | Venous thromboembolic disease (deep vein thrombosis and pulmonary embolism) are common disorders with serious morbid and mortal complications. Given the varied modes of presentation, a high clinical index of suspicion in patients at risk must exist among physicians. Standard therapy has consisted of intravenous unfract... |
31,035 | Current DVT imaging. | Accurate diagnosis of deep venous thrombosis (DVT) is very difficult, and imaging plays a crucial role in the diagnosis or exclusion of DVT. The initial test of choice for diagnosis of acute thigh as well as upper extremity DVT is ultrasound, because of its high accuracy, relatively low cost, portability, and lack of i... |
31,036 | Epidemiology of acute deep vein thrombosis. | Although the factors leading to venous thrombosis have been known for over a century, Virchow's initial model of thrombosis has been extensively refined. Activated coagulation is now recognized to be of primary importance in venous thrombogenesis; the concept of venous injury has been expanded to include molecular chan... |
31,037 | Diabetic myonecrosis in a previously healthy woman and review of a 25-year Mayo Clinic experience. | To describe a case of diabetic myonecrosis, an unusual complication of diabetes mellitus, and to provide an overview of an institutional experience with this condition.</AbstractText>We report the clinical, laboratory, and imaging findings in a 50-year-old woman with no history of diabetes, who was hospitalized because... |
31,038 | Expanded use of transplantation techniques: abdominal wall transplantation and intestinal autotransplantation. | Surgical principles and techniques derived from organ transplantation surgery can provide novel applications in general surgery. We present an update on our 5-year experience with intestinal autotransplantation and abdominal wall transplantation. Nine patients underwent intestinal or multivisceral transplantation with ... |
31,039 | How an undiscovered extensive peripheral pulmonary venous thrombosis destroyed a heart transplant: a case report. | This report details a recent experience with a 56-year-old man affected by an incompetent mitral valve due to Barlow's disease. The patient underwent a mitral valve repair and extracorporeal membrane oxygenator (ECMO) assistance due to postcardiotomy cardiogenic shock. During the ECMO assistance he experienced a left a... |
31,040 | An alternative approach to the central circulation from above the diaphragm. | This is a review of a new fluoroscopically guided safe technique to place tunneled cuffed hemodialysis (HD) catheters via the supraclavicular location. Right supraclavicular catheters were placed in 12 patients who had no patent internal jugular veins. The placements were all successful and without serious complication... |
31,041 | Radiological placement of chest ports in pediatric oncology patients. | A single center's procedural and follow-up results of radiological chest port placement in pediatric oncology patients are presented. Between July 2002 and December 2003, 37 children (20 boys, 17 girls; age range, 4 months to 16 years; mean 6.7 years) underwent chest port placement. All patients received only one port ... |
31,042 | Lemierre's syndrome: how a sore throat can end in disaster. | Lemierre's syndrome is characterised by a history of recent oropharyngeal infection, clinical or radiological evidence of internal jugular vein thrombophlebitis and isolation of an anaerobic pathogen. We present a case report and review the literature. |
31,043 | Brain edema in neurooncology: radiological assessment and management. | Vasogenic brain edema is a common diagnostic and management problem in brain tumor patients. Molecular mechanisms play a role in the pathophysiology, including abnormalities of tumor endothelium, vascular endothelial growth factor and leukotriene synthase. Edema diagnosis is facilitated by the development of neuroradio... |
31,044 | Phase I study of an immunomodulatory thalidomide analog, CC-4047, in relapsed or refractory multiple myeloma. | To assess the safety, efficacy, and immunomodulatory effects of CC-4047 (Actimid; Celgene, San Diego, CA) in patients with relapsed or refractory myeloma.</AbstractText>Twenty-four relapsed or refractory patients were treated with a dose-escalating regimen of oral CC-4047. Clinical responses and adverse effects were id... |
31,045 | Impaired endothelial release of tissue-type plasminogen activator in patients with chronic kidney disease and hypertension. | We have shown that the capacity for local release of tissue-type plasminogen activator (tPA) from the vascular endothelium is impaired in patients with primary hypertension. Because this response is an important protective mechanism against intravascular clotting, we investigated whether this system is also defective i... |
31,046 | Effect of laser photocoagulation on the retinal vessel diameter in branch and macular vein occlusion. | To investigate the response of retinal vessel diameters to photocoagulation treatment and their role for the success of laser treatment in patients with retinal vein occlusion.</AbstractText>The study included 14 patients with branch vein occlusion or macular vein occlusion. The ophthalmologic examination included best... |
31,047 | Hormone replacement therapy in postmenopausal women. | For many years, hormone replacement therapy (HRT) was considered an effective method of restoring the relative protection from coronary artery disease enjoyed by premenopausal women compared with men of similar age. This view has been supported by a substantial number of basic science and observational studies.</Abstra... |
31,048 | [Efficacy of 3-dimensional conformal hypofractionated single high-dose radiotherapy combined with transcatheter arterial chemoembolization for portal vein tumor thrombus in patients with hepatocellular carcinoma]. | <AbstractText Label="BACKGROUND & OBJECTIVE" NlmCategory="OBJECTIVE">Hepatocellular carcinoma (HCC) often results in portal vein tumor thrombus (PVTT), and the prognosis of the patients is extremely poor. It has been reported that some oversea scholars achieved fine therapeutic effects in treatment of this disease ... |
31,049 | Intraoperative venous balloon angioplasty during surgical thoracic outlet decompression in Paget-Schrötter syndrome. | The management of primary subclavian-axillary vein thrombosis is controversial. Indications and time of operative or endovascular intervention after successful thrombolysis remain unresolved. To improve the long-term functional outcomes in patients with primary subclavian-axillary vein thrombosis, early reestablishment... |
31,050 | [Impact of biochemisty on the duration of treatment for pulmonary embolus]. | Can the biochemical evidence for "new thrombophilic factors" influence the duration of AVK treatment following the occurrence of a first pulmonary embolus? Certainly for the classic but very rare antithrombin defects as well as for the existence of circulating anticoagulant. Possibly for protein C and S defects. On the... |
31,051 | MRI findings in pediatric neuro-Behçet's disease. | Behçet's disease (BD), a systemic vasculitis of unknown cause, affects many organs and systems. Neurological involvement is seen in 5-15% of the patients, and the two major forms of neurological disease seen in BD are central nervous system (CNS) parenchymal involvement and cerebral venous sinus thrombosis. We rep... |
31,052 | Effect of age on oral contraceptive-induced venous thrombosis. | This study was undertaken to investigate the effect of age on oral contraceptive-induced venous thrombosis. All women seen in the University of Padua Department of Medical and Surgical Science who had had two courses of oral contraceptive therapy at different ages were included. A total of 28 subjects met these criteri... |
31,053 | Erythropoietin-induced thrombosis as a result of increased inflammation and thrombin activatable fibrinolytic inhibitor. | Chronic inflammation is a major cause of morbidity and mortality in end-stage renal disease. The associated anemia in these patients due to renal cortical atrophy and erythropoietin deficiency is treated with recombinant erythropoietin. Recent reports suggest a growing incidence of symptomatic venous thrombosis in canc... |
31,054 | [Spontaneous muscular haematomas in hemiplegic patients receiving anticoagulation therapy]. | Muscular hematomas are frequently reported as a complication of anticoagulation therapy.</AbstractText>We report six cases of spontaneous muscular hematomas occurring in hemiplegic patients receiving anticoagulation therapy using heparin, low-molecular-weight heparin or fluindione. Anticoagulation therapy was given in ... |
31,055 | Vascular injury during anterior lumbar surgery. | With the number of anterior lumbar procedures expected to increase significantly over the next few years, it is important for spine surgeons to have a good understanding about the incidence of vascular complications during these operations.</AbstractText>To determine the incidence of vascular injury in 1,315 consecutiv... |
31,056 | Thrombotic risk in patients submitted to splenectomy for systemic lupus erythematosus and antiphospholipid antibody syndrome-related thrombocytopenia. | Background: Splenectomy has been performed to treat refractory autoimmune thrombocytopenia. However, some reports have suggested that an increased risk of thrombosis could be present in splenectomized patients. This study aims to evaluate the possibility of an increased risk of thrombosis after splenectomy in patients ... |
31,057 | The antiphospholipid (Hughes') syndrome: changing the face of neurology. | Hughes' syndrome (the antiphospholipid syndrome (APS)) presents with recurrent thrombosis, recurrent miscarriage and neurological disease. The major pathogenic mechanism of the syndrome is vascular obstruction (both venous and arterial) due to hypercoagulability. Neurological manifestations are prominent and are often ... |
31,058 | Perioperative venous thromboembolism prophylaxis in Israel: a survey of academic surgical departments. | Postoperative venous thromboembolism (VTE) represents a serious threat to patients undergoing surgical procedures. Without thromboprophylaxis, deep vein thrombosis occurs in up to 60% of patients undergoing major orthopedic surgery and 15% of patients undergoing major abdominal surgery. Although, many studies have show... |
31,059 | The role of recombinant hirudins in the management of thrombotic disorders. | Native hirudin is the most potent natural direct thrombin inhibitor currently known; it is capable of inhibiting not only fluid phase, but also clot-bound thrombin. Recombinant technology now allows production of recombinant hirudins (r-hirudins), which are available in sufficient purity and quantity with essentially u... |
31,060 | Crohn's disease; analysis of 105 patients. | In this paper, 105 patients with Crohn's disease, (47 M, 58 F), mean age 37.4 +/- 42 years were evaluated clinically, demographically and epidemiologically. Mean age of patients at the time of diagnosis was 26.5 +/- 10.9 years. Follow-up period was 2.7 +/- 2.1 years on average. On admission, symptoms or signs were as f... |
31,061 | Intrahepatic Osler's disease: report of two cases and review of the literature. | Osler-Weber-Rendu disease is a hereditary vascular disease with multiple manifestations. The liver is involved rarely. Vascular abnormalities include telangiectasis and arteriovenous fistulas, sometimes associated with fibrosis and cirrhosis. Hepatic arteriovenous shunting may include secondary portal hypertension, red... |
31,062 | Postoperative adverse events in teaching and nonteaching hospitals. | With the recent attention on quality of care and residency training, teaching hospitals are coming under greater scrutiny. Despite several studies, there is still no consensus on whether teaching hospitals deliver higher quality of care than nonteaching hospitals.</AbstractText>This was a retrospective cross-sectional ... |
31,063 | [Paroxysmal nocturnal hemoglobinuria revealed by hepatic vein thrombosis (Budd-Chiari syndrome) during Infliximab therapy]. | We report the case of a 41-Year-old man presenting with hepatic vein thrombosis (Budd-Chiari syndrome) during Infliximab therapy for ankylosing spondylitis. The systematic work-up revealed paroxysmal nocturnal hemoglobinuria. One Year later the patient was receiving anticoagulation therapy and was in good condition. Th... |
31,064 | [Imaging of the lower limb veins: when and how?]. | Evaluation for possible lower limb deep venous thrombosis (DVT) is a very frequently requested examination. In France, imaging diagnosis is essentially based on complete Doppler sonographic evaluation of both lower limbs. In patients with no co-morbid condition, the D-dimer assay is useful to exclude the possibility of... |
31,065 | Agreement of four competing guidelines on prevention of venous thromboembolism and comparison with observed physician practices: a cross-sectional study of 1,032 medical inpatients. | To assess the degree of agreement between four competing guidelines regarding the recommendation for prophylactic heparin therapy and to report to what extent actual practice agreed with or differed from the recommendations made before these guidelines were disseminated.</AbstractText>Four French guidelines were applie... |
31,066 | [Present state of guidelines for perioperative management of deep vein thrombosis and pulmonary embolism in Japan]. | To clarify the present state of local institutional guideline for perioperative deep thrombosis and pulmonary embolism in individual hospitals, a questionnaire was sent to anesthesia departments in Japan. According to the replies, 82 hospitals have original guidelines. Forty of them reported the contents of their guide... |
31,067 | Value of the D-dimer test in diagnosing deep vein thrombosis in rehabilitation inpatients. | To assess the utility of the D-dimer test-a widely available, less costly, and less time-consuming test than others used to diagnose or exclude deep vein thrombosis (DVT) and pulmonary embolism.</AbstractText>Blind comparison.</AbstractText>An inpatient rehabilitation facility in Turkey.</AbstractText>Sixty-eight conse... |
31,068 | The effectiveness of anticoagulant and antiplatelet agents in preventing venous thromboembolism during stroke rehabilitation: a historical cohort study. | To determine the effectiveness of anticoagulant and antiplatelet agents in preventing venous thromboembolism (VTE) during stroke rehabilitation.</AbstractText>Historical cohort study.</AbstractText>Acute inpatient rehabilitation hospital.</AbstractText>Consecutive patients (N=1506) with ischemic and hemorrhagic stroke ... |
31,069 | Effect of genetic variation in the human S-adenosylhomocysteine hydrolase gene on total homocysteine concentrations and risk of recurrent venous thrombosis. | Hyperhomocysteinemia is an independent and graded risk factor for arterial vascular disease and venous thrombosis. It is still debated via which mechanism homocysteine (Hcy) causes vascular disease. S-adenosylhomocysteine hydrolase (AHCY) catalyses the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to Hcy. As... |
31,070 | Do we need screening for thrombophilia prior to kidney transplantation? | There is increased risk for the occurrence of deep venous thrombosis (DVT) and renovascular thrombosis after kidney transplantation. A disruption of the blood homeostasis caused by surgery and leading to clotting and bleeding malfunctions is widely accepted. However, other causes such as inherited or acquired disorders... |
31,071 | Randomised clinical trial of elective re-siting of intravenous cannulae. | Peripheral venous thrombophlebitis (PVT) represents a considerable source of iatrogenic morbidity, occurring in about 20% of hospital in-patients. The aim of this prospective randomised study was to investigate the effect of elective change of intravenous cannulae on the incidence of PVT in hospital in-patients.</Abstr... |
31,072 | A direct antifibrinolytic agent in major orthopedic surgery. | Aprotinin is a potent pharmacological agent that reduces bleeding. In current surgical practices, the rate of blood transfusions has decreased with the use of aprotinin. Recently, studies using aprotinin have been conducted in orthopedic surgery. Several trials have been performed in patients undergoing total hip repla... |
31,073 | Mesenteric vein thrombosis after surgery and radiotherapy for pancreatic carcinoma. A case report. | A case is reported of a 54-year-old female patient undergoing the resection of a pancreatic carcinoma with intraoperative radiation therapy (10 Gy) on the tumor bed and subsequent external beam radiotherapy (50 Gy). After surgery the patient presented chronic diarrhea resistant to oral pancreatic enzymes. Twenty-five m... |
31,074 | Pylethrombosis associated with gastric cancer in Moschcowitz's disease: successful management with anticoagulant. Report of a case. | Portal vein thrombosis secondary to gastric cancer has been rarely reported. The main difficulty is represented by the correct differential diagnosis between benign and malignant thrombus and therefore by its treatment. In this report we describe a 62-year-old woman with Moschcowitz's disease who developed pylethrombos... |
31,075 | [Indirect MR venography: contrast medium protocols, postprocessing and combination in diagnosing pulmonary emboli with MRI]. | Integration of MR venography in a comprehensive MR imaging protocol in patients with suspected pulmonary embolism (PE) and evaluation of contrast media dosage, timing and postprocessing for diagnostic accuracy.</AbstractText>Forty-eight consecutive inpatients with suspected PE or deep vein thrombosis were examined by M... |
31,076 | [Long-term central venous lines and their complications]. | The implantation of permanent (> 14 days) central venous catheters is constantly increasing, accelerated by a trend toward outpatient therapies. Subcutaneous tunneled and non-tunneled catheters as well as port systems are available. The interventional radiologist plays an important role in the implantation of centra... |
31,077 | DNA microarray-based analysis of single nucleotide polymorphisms may be useful for assessing the risks and benefits of hormone therapy. | To determine what percentage of women can be given individualized counseling based on genetic information, as single nucleotide polymorphisms (SNPs) are associated with risks and benefits of estrogen therapy and hormone therapy such as thrombosis, myocardial infarction, breast cancer, and bone protection.</AbstractText... |
31,078 | [Arteriovenous sheathotomy in venous thrombosis]. | The pathogenesis of branch retinal vein occlusion (BRVO) seems to differ from that of central retinal vein occlusion (CRVO). Arteriosclerotic and anatomic aspects suggest that arteriovenous crossing of vessels may play a significant role. New procedures like arteriovenous decompression have been proposed to be a suitab... |
31,079 | Aprotinin and major orthopedic surgery. | Aprotinin is a potent pharmacological agent that reduces bleeding and limits blood transfusion requirements in current surgical practice. Many studies have been conducted in orthopedic surgery. In several trials performed in total hip replacement (THR) and total knee replacement (TKN) patients, aprotinin only moderatel... |
31,080 | Modification of thrombomodulin plasma levels in refractory myeloma patients during treatment with thalidomide and dexamethasone. | Deep venous thrombosis (DVT) has been variably reported in multiple myeloma patients during treatment with thalidomide alone or in combination with chemotherapy or dexamethasone. With the aim of investigating this complication, we performed, on a cohort of 13 relapsed refractory MM patients treated with low-dose thalid... |
31,081 | Anticoagulation period in idiopathic venous thromboembolism. How long is enough? | The period of anticoagulation of a first episode of idiopathic venous thromboembolism has been 6 months. It is unclear if such patients would benefit from longer treatment, as there appears to be an increased risk of recurrence after anticoagulation is stopped.</AbstractText>In a randomized prospective study of 64 pati... |
31,082 | Risk factors for intraoperative portal vein thrombosis in pediatric living donor liver transplantation. | Pathologic changes of the recipient native portal venous system may cause thrombosis of the portal vein, especially in pediatric living donor liver transplantation (LDLT). This study assessed the utility of Doppler ultrasound (US) for the detection of intraoperative portal vein occlusion and identification of predispos... |
31,083 | Fondaparinux sodium: a review of its use in the prevention of venous thromboembolism following major orthopaedic surgery. | Fondaparinux sodium (Arixtra; fondaparinux) is the first of a new class of synthetic pentasaccharide anticoagulants that bind to antithrombin and inhibit the action of factor Xa. In three large, well designed trials, subcutaneous fondaparinux 2.5mg once daily was more effective than subcutaneous enoxaparin sodium (enox... |
31,084 | Too much lumping in ischemic stroke - a new classification. | The heterogeneity of ischemic stroke syndromes with treatment of disparate categories may be a factor in clinical stroke trial failure. Recent advances include a multitude of stroke investigative modalities that are noninvasive, allowing more precise mechanistic determination.</AbstractText><AbstractText Label="MATERIA... |
31,085 | Positron emission tomography-computed tomography imaging characteristics of an inferior vena cava tumor thrombus with magnetic resonance imaging correlation. | Thrombus of the renal vein or inferior vena cava is a known complication of renal cell carcinoma (RCC). Accurate discrimination between bland and malignant thrombus can have significant implications toward clinical management. Distinguishing between these 2 entities is not usually possible with enhanced computerized to... |
31,086 | Haemophilia and thrombophilia: an unexpected association! | In patients with haemophilia, a close correlation is usually observed between the clinical expression of the disease and plasmatic factor VIII/factor IX clotting activity. However, some patients experience milder bleeding phenotypes than others, although they exhibit a similar biological profile. The high prevalence of... |
31,087 | Graduated compression stockings (20-30 mmHg) do not compress leg veins in the standing position. | Since graduated compression stockings (GCS) reduce the risk of deep venous thrombosis (DVT) in both hospital and ambulant patients, we checked the compressive efficiency of 20-30 mmHg GCS in the standing position.</AbstractText>In 30 volunteers (17 normal legs, 13 varicose legs), duplex ultrasound was used to measure t... |
31,088 | Superior mesenteric venous thrombosis: a retrospective study of thirteen cases. | To analyze the epidemiology, associated risk factors, clinical presentation, diagnostic methods, treatment, and evolution of patients diagnosed with superior mesenteric venous thrombosis (SMVT) at an university hospital in Madrid.</AbstractText>Retrospective and descriptive study. We review the medical records of patie... |
31,089 | Superficial venous thrombosis of the lower extremities: analysis of risk factors, and recurrence and role of anticoagulation. | Superficial venous thrombosis (SVT) of the lower extremities is a common ailment seen in outpatient offices of vascular medicine and surgery practices. This study of 60 consecutive outpatients was carried out to examine the incidence of concomitant deep venous thrombosis (DVT), risk factors associated with SVT, recurre... |
31,090 | [Surgery for deep venous reflux in the lower limb]. | Surgery for deep venous reflux (DVR) in the lower limb had displayed, for various reasons a much more limited development than arterial surgery including endovascular techniques. Importance and frequency of DVR in chronic venous disease and particularly in chronic venous insufficiency (CVI) has been fully identified on... |
31,091 | [Treatment of postcatheterization femoral false aneurysms]. | The incidence of iatrogenic femoral false aneurysms has risen dramatically in recent years and is estimated at 0,5% for diagnostic procedures and may rise to 9% or more for therapeutic procedures. This increased incidence is related to the increased number of arterial punctures performed for diagnostic or therapeutic p... |
31,092 | Physicians' practice for prevention of venous thromboembolism in medical patients. | To audit physicians' practice of providing prophylaxis for venous thromboembolism (VTE) in patients admitted to acute- care medical wards and to determine the consequences of lack of prophylaxis.</AbstractText>Case-control comparative study.</AbstractText>All patients admitted to medical service of Riyadh Medical Compl... |
31,093 | Imaging findings of neuro-Behcet disease. | To study the neuroimaging findings of neuro-Behcet`s disease (NBD) in Saudi patients and to discuss the radiological differential diagnosis.</AbstractText>The clinical data and radiological findings on CT, MRI and cerebral angiography of 16 patients with NBD attending King Khalid University Hospital, Riyadh, Kingdom of... |
31,094 | Heparin-induced thrombocytopenia during renal replacement therapy. | There is increasing awareness that antibodies to heparin/platelet factor 4 complex can develop in both those with acute renal failure treated with continuous forms of renal replacement therapy and, to a lesser extent, regular hemodialysis patients. Clinical manifestations include premature clotting of the extracorporea... |
31,095 | Prevention of hemodialysis-related muscle cramps by intradialytic use of sequential compression devices: a report of four cases. | Hemodialysis (HD)-related lower extremity (LE) muscle cramps are a common cause of morbidity in end-stage renal disease patients on maintenance HD. Numerous pharmacologic and physical measures have been tried with variable success rates.</AbstractText>Sequential compression devices (SCD) improve venous return (VR) and ... |
31,096 | Randomized clinical trial of low molecular weight heparin with thigh-length or knee-length antiembolism stockings for patients undergoing surgery. | This was a randomized clinical trial to determine the efficacy and safety of a 'blanket' protocol of low molecular weight heparin (LMWH) and the best length of antiembolism stocking, for every patient requiring surgery under general anaesthesia.</AbstractText>Of 426 patients interviewed, 376 agreed to be randomized to ... |
31,097 | Excess risk of cancer in patients with primary venous thromboembolism: a national, population-based cohort study. | We conducted a nationwide, retrospective cohort study assessing the risk of cancer in VTE patients diagnosed in Scotland in 1982-2000. Significantly elevated risks of cancer were sustained for 2 years after VTE diagnosis, most notably for ovarian tumours and lymphomas. Younger patients were at an increased relative ris... |
31,098 | [Diagnostic and therapeutic progress. Venous thromboembolism, cardiac insufficiency and radio contrast agents]. | MODALITIES FOR THE DIAGNOSIS OF VENOUS THROMBOEMBOLISM: Currently rely on the confrontation of the initial clinical data and the results of D-dimer measurements, a venous Doppler, although reliable, is not a first-line exploration. REGARDING TREATMENT: Indications for thrombolysis are currently limited to massive pulmo... |
31,099 | Cost savings and effectiveness of outpatient treatment with low molecular weight heparin of deep vein thrombosis in a community hospital. | This study was conducted at Centenary Health Centre of the Rouge Valley Health System, a community based hospital in Toronto. In January 1997, a new treatment was introduced for the management of patients with uncomplicated deep vein thrombosis (DVT). Eligible patients presenting at the ER were placed on LMWH (tinzapar... |
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