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6,700
Atrial fibrillation and heart failure in cardiology practice: reciprocal impact and combined management from the perspective of atrial fibrillation: results of the Euro Heart Survey on atrial fibrillation.
Our aim was to identify shortcomings in the management of patients with both atrial fibrillation (AF) and heart failure (HF).</AbstractText>AF and HF often coincide in cardiology practice, and they are known to worsen each other's prognosis, but little is known about the quality of care of this combination.</AbstractTe...
6,701
Accelerated idioventricular rhythm associated with desflurane anesthesia :A case report.
Accelerated idioventricular rhythm is defined as a ventricular rhythm of 60-100 beats per minute or a ventricular tachycardia that does nor exceed 120 beats per minutes. Although, it rarely converts to a fatal arrhythmia like ventricular fibrillation, it needs to be differentiated from AIVR, which is from another origi...
6,702
[Poisoning with antidepressants].
Intoxications with medications are among the most frequent diagnoses in patients admitted to medical emergency departments and intensive care units. Due to their particular toxicity tricyclic antidepressants play an important role despite a decreasing incidence. Tricyclic antidepressant toxicity includes an inhibition ...
6,703
Antifibrillatory agents and potassium channels in the atria: pore block versus channel trafficking.
Atrial fibrillation (AF) is the most common cardiac arrhythmia. The preferred therapy for AF is sustained sinus rhythm control; however, the efficacy of currently used antiarrythmic drugs is limited by adverse side effects resulting from both a lack of ion channel selectivity and nonspecific ventricular activity. The r...
6,704
Selective treatment algorithm for mitral valve annuloplasty in nonischemic functional mitral regurgitation.
The success rate of mitral annuloplasty (MA) for functional mitral regurgitation (FMR) varies. This study evaluated the effectiveness of this procedure in nonischemic dilated cardiomyopathy (DCM) patients after a selective treatment protocol was followed.</AbstractText>This study analyzed 42 patients with nonischemic D...
6,705
Prevalence and physiological predictors of sleep apnea in patients with heart failure and systolic dysfunction.
Previous studies reported high prevalences of obstructive and central sleep apnea (OSA and CSA, respectively) in patients with heart failure (HF). However, these preceded widespread use of beta-blockers and spironolactone that might have reduced their prevalences. We therefore determined, in patients with HF, prevalenc...
6,706
Ventricular fibrillation induced by a radiofrequency energy delivery for idiopathic premature ventricular contractions arising from the left ventricular anterior papillary muscle.
A 73-year-old man with idiopathic premature ventricular contractions (PVCs) underwent electrophysiological testing. Left ventricular activation mapping revealed a focal mechanism of the PVCs with the earliest activation on the anterior papillary muscle (APM). Irrigated radiofrequency (RF) current delivered at that site...
6,707
Cerebral metabolic rate of oxygen (CMRO2) in pig brain determined by PET after resuscitation from cardiac arrest.
To assess the regional vulnerability to ischemic damage and perfusion/metabolism mismatch of reperfused brain following restoration of spontaneous circulation (ROSC) after cardiac arrest.</AbstractText>We used positron emission tomography (PET) to map cerebral metabolic rate of oxygen (CMRO(2)), cerebral blood flow (CB...
6,708
Regional prevalence and clinical benefit of implantable cardioverter defibrillators in Brugada syndrome.
Brugada syndrome (BS) is associated with an increased risk of sudden cardiac death (SCD) caused by ventricular tachyarrhythmia. Thus, implantable cardioverter defibrillators (ICD) became the main therapeutic option in these patients. We aimed to investigate the prevalence of BS in the Eastern Alps as well as the benefi...
6,709
Acute efficacy of combined therapy of carperitide and nicorandil for acute decompensated heart failure with left ventricular systolic dysfunction.
A 64-year-old woman was admitted to our hospital with acute decompensated heart failure (ADHF) and left ventricular systolic dysfunction. Initial treatment with carperitide (0.01 &#xb5;g/kg/min) had little effect. Since she had a borderline systolic blood pressure (i.e., a systolic BP between 90 and 110 mm Hg) and atri...
6,710
Off-pump transapical mitral valve replacement.
Percutaneous valve replacement was recently introduced, and reports of early clinical experience have already been published. To date, this technique is limited to the replacement of pulmonary and aortic valves in a strictly selected group of patients. The aim of this study was to analyse a self-expanding valved stent ...
6,711
Catheter ablation of fatal ventricular tachyarrhythmias storm in acute coronary syndrome--role of Purkinje fiber network.
Ventricular fibrillation (VF) or ventricular tachycardia (VT) storm is a life-threatening arrhythmia. Antiarrhythmic drugs (AADs) are not necessarily effective to rescue life from such conditions. Catheter ablation (CA) targeting triggering premature ventricular contractions (PVCs) of VF or VT that originates from Purk...
6,712
Rapid ventricular pacing to optimize rotational angiography in atrial fibrillation ablation.
Conventional pulmonary vein (PV) angiography cannot precisely delineate the left atrium (LA)-PV anatomy, which is essential for the ablation of atrial fibrillation (AF). The aim of the study was to test the feasibility of a novel method of rotational angiography for the AF ablation.</AbstractText>Forty-one patients wer...
6,713
Cardiopulmonary resuscitation: outcome and its predictors among hospitalized adult patients in Pakistan.
Our aim was to study the outcomes and predictors of in-hospital cardiopulmonary resuscitation (CPR) among adult patients at a tertiary care centre in Pakistan.</AbstractText>We conducted a retrospective chart review of all adult patients (age &gt; or =14 years), who underwent CPR following cardiac arrest, in a tertiary...
6,714
Treatment of ventricular arrhythmias in the elderly.
Underlying causes of ventricular tachycardia (VT) or complex ventricular arrhythmias (VA) should be treated if possible. Antiarrhythmic drugs should not be administered to treat asymptomatic individuals with complex VA and no heart disease. Beta-blockers are the only antiarrhythmic drugs that have been documented to re...
6,715
Tentacles: a novel device for exposing the heart for the insertion of left apical assist device cannulae.
The implantation of ventricular assist devices is a well-established procedure for the treatment of imminent heart failure. The exact positioning of the left ventricular apical inflow cannula is crucial, because inflow restrictions might occur when the cannula is placed too close to the interventricular septum or a pap...
6,716
What should be the primary treatment in atrial fibrillation: ventricular rate control or sinus rhythm control with long-term anticoagulation?
Recent trials have favoured ventricular rate control in atrial fibrillation (AF) management, however the present study investigated whether the restoration and maintenance of sinus rhythm with long-term anticoagulation therapy was superior in terms of embolic events and death in 534 patients with an AF duration &gt; 48...
6,717
Oral magnesium prophylaxis provides spontaneous resumption of cardiac rhythm in patients undergoing cardiac surgery.
Evidence is growing that magnesium supplementation in patients undergoing cardiac surgery is beneficial, however the best administration route has not been established. Previously, we showed that intra-operative direct flush infusion of magnesium into the aortic root before reperfusion was effective. The present study ...
6,718
Cardiac resynchronization therapy in NYHA class IV heart failure.
Clinical practice guidelines recommend cardiac resynchronization therapy (CRT) for ambulatory New York Heart Association (NYHA) class IV patients with a QRS duration &gt;or= 120 ms and a left ventricular ejection fraction &lt;or= 35%. Only two prospective, randomized trials have compared outcomes after CRT in NYHA clas...
6,719
AED use in a passenger during a long-haul flight: repeated defibrillation with a successful outcome.
Sudden cardiac arrest is one of the leading causes of death, and early defibrillation of ventricular fibrillation (VF) is the single most important intervention for improving survival. The automated external defibrillator (AED) and the concept of public access defibrillation provide a solution to shorten defibrillation...
6,720
Effects of exercise testing on natriuretic peptide secretion in patients with atrial fibrillation.
Assessment of endocrine profile in patients with cardiovascular diseases has become increasingly important during the last decade. Plasma brain natriuretic peptide (BNP) levels have been used as a marker of left ventricular dysfunction. However, the role of BNP in patients with atrial fibrillation (AF) and normal left ...
6,721
Successful catheter ablation of focal ventricular fibrillation originating from the right ventricle.
Sudden cardiac death from ventricular fibrillation (VF) typically occurs in patients with structural heart disease, but in 5 to 10 percent VF is "idiopathic," occurring in normal hearts. Recently, there has been the description and growing recognition of patients with VF that has a focal origin, the common sites being ...
6,722
Atrial tachycardia initiating atrial fibrillation successfully ablated in the non-coronary cusp of the aorta.
A 60-year-old woman was referred for catheter ablation of atrial fibrillation (AF). Atrial flutter and atrial tachycardia (AT) also had been clinically documented. During the electrophysiological study, the clinical AT was induced by burst atrial pacing during isoproterenol infusion and exhibited negative P waves in th...
6,723
Post placement positional atrial fibrillation and peripherally inserted central catheters.
Arrhythmias are common in hospitalized patients and during surgery. We present a case of positional atrial arrhythmia related to a peripherally inserted central catheter (PICC). There are other documented case reports of ventricular tachycardia precipitated by body position changes with a PICC. The immediate correction...
6,724
Life-threatening left main stenosis induced by compression from a dilated pulmonary artery.
On a rare occasion, pulmonary artery dilatation can be complicated by an extrinsic compression of the left main coronary artery (LMCA) whose effects are immediately evident, whereas a delayed presentation is unusual. We report the uncommon case of a delayed acute coronary syndrome caused by the extrinsic compression of...
6,725
Effect of biventricular pacing on ventricular repolarization and functional indices in patients with heart failure: lack of association with arrhythmic events.
We prospectively assessed the effects of biventricular (BiV) pacing on electrocardiographic (ECG) and vectorcardiographic (VCG) descriptors of ventricular depolarization and repolarization and their association with appropriate implantable cardioverter defibrillator (ICD) activation.</AbstractText>We studied 70 consecu...
6,726
Exploring QT interval changes as a precursor to the onset of ventricular fibrillation/tachycardia.
In the present study, we have retrospectively analyzed the corrected QT (QTc) interval before spontaneous episodes of sudden cardiac arrest in patients with a wearable cardioverter defibrillator. Corrected QT interval was measured for all normal beats from 32 recordings of baseline rhythm and compared to normal rhythm ...
6,727
Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin with rapamycin plus tacrolimus in liver transplant patient.
To report a severe interaction between simvastatin and rapamycin resulting in rhabdomyolysis and acute renal failure in a liver transplant patient.</AbstractText>A 56-year-old man with hepatitis C virus cirrhosis (Child B) was diagnosed with hepatocellular carcinoma and underwent liver transplantation in April 2007. He...
6,728
Doppler-derived preoperative mitral regurgitation volume predicts postoperative left ventricular dysfunction after mitral valve repair.
Unexpected postoperative left ventricular (LV) dysfunction after valve repair for mitral regurgitation (MR) occurs in some patients with normal preoperative LV function. Identification of factors that predispose to such LV dysfunction would enhance our understanding of the indications and outcomes of surgery.</Abstract...
6,729
The patient with atrial fibrillation.
Atrial fibrillation is a frequently encountered arrhythmia, particularly affecting the elderly. Patients at significant risk for stroke should be considered for anticoagulation with warfarin. Management of atrial fibrillation revolves around either controlling the ventricular rate response or trying to maintain sinus r...
6,730
Out of hospital cardiac arrest outside home in Sweden, change in characteristics, outcome and availability for public access defibrillation.
A large proportion of patients who suffer from out of hospital cardiac arrest (OHCA) outside home are theoretically candidates for public access defibrillation (PAD). We describe the change in characteristics and outcome among these candidates in a 14 years perspective in Sweden.</AbstractText>All patients who suffered...
6,731
Impact of induced cardiac arrest on cognitive function after implantation of a cardioverter-defibrillator.
Implantable cardioverter-defibrillators (ICD) were introduced in clinical practice in 1980 and they are considered the standard treatment for individuals at risk for fatal ventricular arrhythmias. To ensure proper working conditions, the energy necessary to interrupt ventricular tachycardia or ventricular fibrillation ...
6,732
Erythropoietin facilitates the return of spontaneous circulation and survival in victims of out-of-hospital cardiac arrest.
Erythropoietin activates potent protective mechanisms in non-hematopoietic tissues including the myocardium. In a rat model of ventricular fibrillation, erythropoietin preserved myocardial compliance enabling hemodynamically more effective CPR.</AbstractText>To investigate whether intravenous erythropoietin given withi...
6,733
Resuscitation after cardiac surgery: results of an international survey.
A survey was conducted on CTSNet, the cardiothoracic network website in order to ascertain an international viewpoint on a range of issues in resuscitation after cardiac surgery.</AbstractText>From 40 questions, 19 were selected by the EACTS clinical guidelines committee. Respondents were anonymous but their location w...
6,734
Implementing cardiac resynchronization therapy in routine clinical practice: preoperative considerations and implantation techniques.
Cardiac resynchronization therapy (CRT) using coronary sinus (CS) leads is an established therapy for congestive heart failure in patients with asynchronous ventricular contractions. CRT improves not only exercise tolerance but also the patient's prognosis. Appropriate patient selection for CRT is essential for a succe...
6,735
Mortality and atrial fibrillation: is there a causal relationship?
Almost all studies show that atrial fibrillation (AF) is associated with increased mortality. What is less certain is whether this association is a straightforward cause-and-effect relationship, or if AF is merely a marker of severity of cardiovascular disease(s) or the aging process. AF can lead to the worsening of le...
6,736
Sevoflurane postconditioning converts persistent ventricular fibrillation into regular rhythm.
Recent studies showed that ischaemic postconditioning converted persistent ventricular fibrillation to sinus rhythm. The influence of anaesthetic postconditioning on ventricular fibrillation has not yet been determined. In the present study, we studied the possible effect of sevoflurane postconditioning on persistent r...
6,737
Effects of lipid-altering therapies on ventricular arrhythmias and sudden cardiac death.
Sudden cardiac death remains a leading cause of mortality in the United States, with an incidence of 300,000 to 400,000 deaths annually. Despite advances in the management of cardiovascular disease, the only effective treatments proven to reduce the risk of sudden cardiac death are beta-adrenergic blockers and implanta...
6,738
Catheter ablation of a posteroseptal accessory pathway in a case with congenital long QT syndrome.
A 23-year-old woman with pre-excitation who was resuscitated from ventricular fibrillation underwent electrophysiologic testing. Successful catheter ablation of a left posteroseptal accessory pathway was achieved. Though the JT and JTc intervals as well as QT and QTc intervals were prolonged before and one day after th...
6,739
Short QT syndrome in a pediatric patient.
Short QT syndrome (SQTS) is a recently described genetic syndrome characterized by abnormally brisk ventricular repolarization. Similar to long QT syndrome, SQTS might result in ventricular arrhythmias, syncope, and sudden death. The clinical diagnosis of SQTS is supported by the finding of an abnormally short QT inter...
6,740
[Case of undiagnosed vasospastic angina first noted during anesthesia].
A 75-year-old man patient was scheduled for total gastrectomy, splenectomy, and cholecyctectomy who had been hypertensive. The patient had no symptoms related to cardiac disease before surgery. Preoperative ECG showed only complete right bundle branch block. After arriving in the operating room, epidural anesthesia was...
6,741
Antiplatelet drugs for ischemic stroke prevention.
In primary prevention trials conducted in low-risk subjects, aspirin is associated with a small reduction in ischemic strokes in women. It also reduces the incidence of stroke in patients with nonvalvular atrial fibrillation (NVAF), but warfarin is more effective in patients with high blood pressure, or left ventricula...
6,742
Cardioembolic stroke: call for a multidisciplinary approach.
Cardioembolic stroke accounts for one third of all ischemic strokes, and atrial fibrillation (AF) is the cardiac source of emboli in 50% of them. However, the absolute risk of stroke associated with AF has enormous variability, and several clinical risk stratification schemes have been proposed. One of the most validat...
6,743
Impacts of ventricular rate regularization pacing at right ventricular apical vs. septal sites on left ventricular function and exercise capacity in patients with permanent atrial fibrillation.
The deleterious effects of right ventricular apex (RVA) pacing may offset the potential benefit of ventricular rate (VR) regularization during atrial fibrillation (AF). Recent studies suggested that right ventricular septal (RVS) pacing may prevent the potential deleterious effects of RVA pacing and enhance the VR regu...
6,744
Multicenter clinical experience with an atrial lead designed to minimize far-field R-wave sensing.
To evaluate a novel atrial lead designed to reduce far-field sensing.</AbstractText>Sixty-three patients with standard pacing indications were randomized to receive an OptiSense 1699T (St Jude Medical, USA) or conventional pacing lead in the right atrium. Post-implant follow-up was conducted for all patients at 90 days...
6,745
Plasma endothelin-1 level at the onset of ischemic ventricular fibrillation predicts resuscitation outcome.
Endogenous vasopressors, including endothelin-1 (ET-1), have been shown to be elevated in patients following resuscitation from out-of-hospital cardiac arrest and are likely a physiologic response to global ischaemia. The importance of ET-1 in the setting of arrest and resuscitation has not been established. Prior work...
6,746
Use of a thrombelastograph platelet mapping assay for diagnosis of clopidogrel resistance: a case report.
A 62-year-old woman presented to the emergency department with sudden collapse, intractable ventricular fibrillation, and an inferior wall myocardial infarction (MI). An emergent cardiac catheterization showed a totally occluded right coronary artery (RCA). A bare-metal stent was placed in the stenosis, resulting in th...
6,747
Dose-response effects of bepridil in patients with persistent atrial fibrillation monitored with transtelephonic electrocardiograms: a multicenter, randomized, placebo-controlled,double-blind study (J-BAF Study).
A multicenter, randomized, placebo-controlled, double-blind trial was conducted with patients with persistent atrial fibrillation (AF) to determine the dose-response effects and safety of bepridil, using every-day transtelephonic monitorings.</AbstractText>A total of 90 patients were randomized to receive placebo, 100 ...
6,748
QRS prolongation is associated with high defibrillation thresholds during cardioverter-defibrillator implantations in patients with hypertrophic cardiomyopathy.<Pagination><StartPage>1028</StartPage><EndPage>1032</EndPage><MedlinePgn>1028-32</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategor...
Sudden cardiac death (SCD) - this natural death caused by cardiac reasons and which is characterized by sudden loss of consciousness within first hour after revealing of sharp clinical symptoms. A primary factor of SCD is not traumatic. It occurs suddenly and unexpectedly. The high risk of development of sudden cardiac...
6,749
Effect of cardiac resynchronization therapy on the incidence of electrical storm.
Hemodynamic improvement from biventricular pacing is well documented; however, its electrophysiologic effects have not been systematically studied. In this study, incidence and risk factors for electrical storm (ES) were investigated in 729 ICD and biventricular defibrillator (CRT-D) heart failure patients.</AbstractTe...
6,750
Atrial flutter, ventricular tachycardia and changing axis deviation associated with scleroderma.
Rhythm disturbances have been described in immunological and connective diseases. Scleroderma is a fibrotic condition characterized by immunological abnormalities, vascular injury and increased accumulation of extracellular matrix proteins. The heart is one of the major organs involved in scleroderma, the involvement o...
6,751
Effects of verapamil on anterior ST segment and ventricular fibrillation cycle length in patients with Brugada syndrome.
This study examined the effects of verapamil (5-10 mg intravenous) on the cardiac electrical activity of 10 Brugada syndrome (BS) patients having vasospastic angina, atrial fibrillation, and/or hypertension.</AbstractText>Verapamil showed no significant change in the ST-segment elevation. Likewise, there was no signifi...
6,752
Outcomes in mitral regurgitation due to flail leaflets a multicenter European study.
The purpose of this study was to assess incidence and predictors of events associated with nonsurgical and surgical management of severe mitral regurgitation (MR) in European institutions.</AbstractText>The management of patients with MR remains disputed, warranting multicenter studies to define clinical outcome in rou...
6,753
Management of primary aldosteronism: its complications and their outcomes after treatment.
Primary aldosteronism is the most common cause of secondary hypertension, accounting for about 10% of all forms of high blood pressure. Life-time pharmacological therapy is the treatment of choice for primary aldosteronism due to idiopathic adrenal hyperplasia (IHA), while adrenalectomy is effective in curing most pati...
6,754
Selective beta blockade improves the outcome of cardiopulmonary resuscitation in a swine model of cardiac arrest.
Epinephrine has been the mainstay drug of choice for cardiac resuscitation for more than 30 years. Its vasopressor effects favoring initial resuscitation point to its beta-adrenergic action. However, its beta-adrenergic actions may have detrimental effects. The aim of the present experimental study was to evaluate the ...
6,755
hERG1 channel activators: a new anti-arrhythmic principle.
The cardiac action potential is the result of an orchestrated function of a number of different ion channels. Action potential repolarisation in humans relies on three potassium current components named I(Kr), I(Ks) and I(K1) with party overlapping functions. The ion channel alpha-subunits conducting these currents are...
6,756
Susceptibility genes &amp; modifiers for cardiac arrhythmias.
Cardiac arrhythmias in the absence of structural heart diseases can be subdivided in those cases which are acquired and those which are linked to genetic defects on cardiac ion channels and regulatory subunits. Although acquired arrhythmias do not contain any obviously genetic component the observation of frequently oc...
6,757
A single-cell model of phase-driven control of ventricular fibrillation frequency.
The mechanisms controlling the rotation frequency of functional reentry in ventricular fibrillation (VF) are poorly understood. It has been previously shown that Ba2+ at concentrations up to 50 mumol/L slows the rotation frequency in the intact guinea pig (GP) heart, suggesting a role of the inward rectifier current (I...
6,758
Electrical storm in Brugada syndrome successfully treated with orciprenaline; effect of low-dose quinidine on the electrocardiogram.
We report a case of an electrical storm occurring in a patient implanted with a cardioverter defibrillator for symptomatic Brugada syndrome. Recurrent ventricular fibrillation was initiated by short-coupled premature ventricular beats of right ventricular origin, associated with a fixed Brugada type 2 electrocardiograp...
6,759
Sudden cardiac arrest due to puerperal transient left ventricular apical ballooning syndrome.
A 37 year old woman with chest pain was admitted to the emergency room 40&#xa0;days after normal delivery with ventricular fibrillation due to Takotsubo cardiomyopathy.
6,760
SCN5A mutation associated with acute myocardial infarction.
Ventricular tachycardia and fibrillation (VT/VF) complicating Brugada syndrome, a genetic disorder linked to SCN5A mutations, and VF complicating acute myocardial infarction (AMI) have both been linked to phase 2 reentry. Because of these mechanistic similarities in arrhythmogenesis, we examined the contribution of SCN...
6,761
Interatrial conduction time and left atrial function in patients with left ventricular systolic dysfunction: effects of cardiac resynchronization therapy.
Prolonged interatrial conduction time (IACT) can be associated with abnormal left atrial (LA) function but has not been characterized in patients with left ventricular (LV) systolic dysfunction (LVSD) and QRS intervals &gt;130 ms.</AbstractText>Two-dimensional Doppler echocardiography and Doppler tissue imaging (DTI) w...
6,762
Valsalva maneuver to predict dynamic intraventricular obstruction during dobutamine stress echocardiography in patients with hypertension.
We were to evaluate the effect of Valsalva maneuver with comparison to preload reduction by nitroglycerin (NTG) to predict intraventricular obstruction (IVO) during dobutamine stress echocardiography (DSE) in patients with hypertension.</AbstractText>A total of 38 hypertensive patients (mean age 66.0&#xb1;9.9 years; 32...
6,763
Optimization of feedback pacing for defibrillation.
A mathematical model of multisite feedback pacing for defibrillation is optimized for electrode spacing and stimulus period. For four electrodes, the defibrillation success rate is highest at 88% when the electrodes are spaced as far apart as possible. For a single electrode, the optimum success rate was 26%.
6,764
CPR artifact removal in ventricular fibrillation ECG signals using Gabor multipliers.
We present an algorithm for discarding cardiopulmonary resuscitation (CPR) components from ventricular fibrillation ECG (VF ECG) signals and establish a method for comparing CPR attenuation on a common dataset. Removing motion artifacts in ECG allows for uninterrupted rhythm analysis and reduces "hands-off" time during...
6,765
Intelligent analysis in predicting outcome of out-of-hospital cardiac arrest.
The prognosis among patients who suffer out-of-hospital cardiac arrest is poor. Higher survival rates have been observed only in patients with ventricular fibrillation who were fortunate enough to have basic and advanced life support initiated early after cardiac arrest. The ability to predict outcomes of cardiac arres...
6,766
Left ventricular hypertrabeculation/noncompaction associated with coronary heart disease and myopathy.
The association of left ventricular hypertrabeculation (LVHT), also known as noncompaction, coronary heart disease, and metabolic myopathy, as presented in the following report, is rare.</AbstractText>In a 77-yo male with a history of arterial hypertension, coronary heart disease, dilative cardiomyopathy, mitral and tr...
6,767
The mechanisms of atrial fibrillation in hyperthyroidism.
Atrial fibrillation (AF) is a complex condition with several possible contributing factors. The rapid and irregular heartbeat produced by AF increases the risk of blood clot formation inside the heart. These clots may eventually become dislodged, causing embolism, stroke and other disorders. AF occurs in up to 15% of p...
6,768
Mode of frequency distribution of external work efficiency of arrhythmic beats during atrial fibrillation remains normal in canine heart.
The external work (EW) efficiency of individual arrhythmic beats of the left ventricle (LV) cannot directly be obtained since LV O(2) consumption (VO(2)) of each beat cannot directly be measured under beat-to-beat varying contractile and loading conditions. We, however, have recently reported that VO(2) of each arrhyth...
6,769
Predictors of atrial fibrillation recurrence in patients with long-lasting atrial fibrillation.
Limited data are available on the predictors of atrial fibrillation (AF) recurrence in patients with chronic AF.</AbstractText>To evaluate potential clinical, echocardiographic and electrophysiological predictors of AF recurrence, after internal cardioversion for long-lasting AF.</AbstractText>A total of 99 consecutive...
6,770
Acetylcholine-regulated K+ current remodelling in the atrium after myocardial infarction and valsartan administration.
Atrial fibrillation (AF) is a common complication of myocardial infarction (MI). Angiotensin II receptor antagonists prevent the promotion and propagation of AF. However, the activation of the acetylcholine-regulated K(+) current (I(K,ACh)) in the atrium after MI and the effect of valsartan on I(K,ACh) are less underst...
6,771
Predictors of atrial tachyarrhythmias in subjects with type 1 ECG pattern of Brugada syndrome.
Previous studies have demonstrated a high incidence of atrial tachyarrhythmias (ATs) in patients with Brugada syndrome (BS). The present study aimed to investigate whether various 12-lead electrocardiogram (ECG) and electrophysiological parameters may help to differentiate subjects with a high probability to develop AT...
6,772
Use of implantable cardioverter-defibrillator in inherited arrhythmogenic diseases: data from Italian ICD Registry for the years 2001-6.
Previous studies have demonstrated the lifesaving role of an implantable cardioverter-defibrillator (ICD) in high-risk patients with genetic arrhythmogenic diseases.</AbstractText>To evaluate the clinical data of patients with hypertrophic cardiomyopathy (HCM), arrhythmogenic right ventricular cardiomyopathy (ARVD/C), ...
6,773
Search for the optimal right ventricular pacing site: design and implementation of three randomized multicenter clinical trials.
The optimal site to permanently pace the right ventricle (RV) has yet to be determined. To address this issue, three randomized prospective multicenter clinical trials are in progress comparing the long-term effects of RV apical versus septal pacing on left ventricular (LV) function. The three trials are Optimize RV Se...
6,774
I(Kur)/Kv1.5 channel blockers for the treatment of atrial fibrillation.
Atrial fibrillation (AF) is the most common sustained arrhythmia. Anti-arrhythmic drugs remain the mainstay of therapy, but the available class I and III anti-arrhythmic drugs are only moderately effective in long-term restoring/maintaining sinus rhythm (SR) and can produce potentially fatal ventricular pro-arrhythmia....
6,775
[Molecular mechanism of the changes in ventricular electrical remodeling caused by mechano-electrical feedback in rabbits with congestive heart failure].
This study sought to explore the relationship between the change in ventricular electrical remodeling caused by mechano-electrical feedback and the expression of L-type Ca2+ -channel and/or sarcoplasmic reticulum Ca2+ -ATPase in the rabbits with congestive heart failure (CHF). 138 rabbits were divided into two groups (...
6,776
[Specific effects of selective anxiolytic afobazole on the cardiovascular system].
Experiments in narcotized rats showed the new selective anxiolytic afobazole, a derivative of 2-mercaptobenzimidazole, to cause a small bradycardia with almost no effect on the important parameters of heart hemodynamics and cardiac performance such as the arterial pressure, cardiac output, and mean aorta blood flow acc...
6,777
Atrial Fibrillation: The New Epidemic of the Ageing World.
The prevalence of atrial fibrillation (AF) increases with age. As the population ages, the burden of AF increases. AF is associated with an increased incidence of mortality, stroke, and coronary events compared to sinus rhythm. AF with a rapid ventricular rate may cause a tachycardia-related cardiomyopathy. Immediate d...
6,778
A Comparative Study to Determine the Effect of Intravenous Magnesium on Postoperative Bleeding after on Pump CABG in Patients Receiving Pre-Operative Aspirin.
Hypomagnesaemia is a common complication after cardiopulmonary bypass (CPB) and predisposes to the development of cardiac arrhythmias. Previous studies showed that intravenous magnesium reduces the incidence of postoperative cardiac arrhythmias but it also inhibits platelet function. Our aim was to compare the postoper...
6,779
Role of magnesium in preventing post-operative atrial fibrillation after coronary artery bypass surgery.
To assess the role of 3 days of magnesium infusion after coronary artery bypass graft (CABG) surgery in preventing postoperative atrial fibrillation (AF).</AbstractText>Armed Forces Institute of Cardiology (AFIC) &amp; National Institute of Heart Diseases (NIHD), Rawalpindi, from July 2006 to June 2007.</AbstractText>P...
6,780
Circadian patterns in the occurrence of malignant ventricular tachyarrhythmias triggering defibrillator interventions in patients with hypertrophic cardiomyopathy.
Sudden death in hypertrophic cardiomyopathy (HCM) has been reported to occur most frequently in the early morning hours, similar to the pattern observed in ischemic heart disease. However, little is known about the circadian pattern of life-threatening arrhythmias in HCM in the contemporary era of the implantable cardi...
6,781
Influence of patient age and sex on delivery of guideline-recommended heart failure care in the outpatient cardiology practice setting: findings from IMPROVE HF.
The influence of patient age and sex on delivery of guideline-recommended heart failure (HF) therapies in contemporary outpatient settings has not been well studied. The Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF) is a prospective cohort study designed to...
6,782
Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease.
There is controversy regarding whether obstructive sleep apnea is responsible for triggering myocardial ischemia, arrhythmias and heart rate variability in patients with coronary artery disease.</AbstractText>The objective of this study was to identify relationships between sleep apnea, myocardial ischemia and cardiac ...
6,783
Minimally invasive mitral valve surgery through right thoracotomy in patients with patent coronary artery bypass grafts.
We report our institutional experience, with 25 consecutive patients with patent coronary artery bypass grafts (71.8+/-12.7 years), who underwent video-assisted minithoracotomic approach for mitral valve surgery. The surgical technique includes: right minithoracotomy, femoral cannulation and hypothermic ventricular fib...
6,784
Physiology and pathology of TASER electronic control devices.
TASER ECDs (electronic control device) are small, battery powered, handheld devices. They deliver short duration, low energy pulses to stimulate motor neurons, causing transient paralysis. While the experience is painful, proper use of the device is rarely associated with significant side effects in spite of 1070 human...
6,785
Does preoperative atrial fibrillation increase the risk for mortality and morbidity after coronary artery bypass grafting?
Preoperative atrial fibrillation has been associated with less favorable outcomes in patients undergoing coronary artery bypass grafting. However, it was never investigated in a large cohort of patients using a national database. This study aims to (1) identify the effect of atrial fibrillation on operative mortality a...
6,786
Relation of left atrial volume from three-dimensional computed tomography to atrial fibrillation recurrence following ablation.
The effect of left atrial (LA) structural remodeling and dilatation on the outcome of ablation of atrial fibrillation (AF) remains unknown. We correlated potential prognostic markers of AF ablation, including LA volume from computed tomography, with AF recurrence after ablation. We studied 73 consecutive patients (52 w...
6,787
Cardiac arrest survival after implementation of automated external defibrillator technology in the in-hospital setting.
Survival from ventricular tachycardia (VT) or ventricular fibrillation (VF) arrest is inversely related to delay to defibrillation. The automated external defibrillator (AED) has improved survival after out-of-hospital VT/VF arrest by decreasing time to defibrillation. The purpose of this study was to determine whether...
6,788
NT-proBNP for pulmonologists: not only a rule-out test for systolic heart failure but also a global marker of heart disease.
Recognizing heart disease is relevant to pulmonologists because many patients suspected to have dyspnea of pulmonary origin harbor heart disease.</AbstractText>To investigate the role of N-terminal pro-brain natriuretric peptide (NT-proBNP) in identifying heart disease and cardiac causes of dyspnea among patients refer...
6,789
Clinical impact of evaluation of cardiovascular control by novel methods of heart rate dynamics.
Heart rate variability (HRV) has been conventionally analysed with time- and frequency-domain methods, which measure the overall magnitude of RR interval fluctuations around its mean value or the magnitude of fluctuations in some predetermined frequencies. Analysis of heart rate dynamics by novel methods, such as heart...
6,790
Mode and mechanisms of death after orthotopic heart transplantation.
Ventricular fibrillation (VF) is the primary mechanism of cardiac arrest in the vast majority of sudden death patients. Whether similar modes and mechanisms of death can be generalized to denervated hearts in orthotopic heart transplantation (OHT) patients is unknown.</AbstractText>The purpose of this study was to dete...
6,791
Differential effects of cardiac sodium channel mutations on initiation of ventricular arrhythmias in patients with Brugada syndrome.
Premature ventricular contractions (PVCs) do not occur frequently but can induce ventricular fibrillation (VF) in patients with Brugada syndrome. The effect of SCN5A mutation on the onset of ventricular arrhythmias is unknown.</AbstractText>The purpose of this study was to evaluate PVC morphology and onset of VF in pat...
6,792
Atrial cellular electrophysiological changes in patients with ventricular dysfunction may predispose to AF.
Left ventricular systolic dysfunction (LVSD) is a risk factor for atrial fibrillation (AF), but the atrial cellular electrophysiological mechanisms in humans are unclear.</AbstractText>This study sought to investigate whether LVSD in patients who are in sinus rhythm (SR) is associated with atrial cellular electrophysio...
6,793
Recent advances in the management of coronary artery disease: highlights from the literature.
The recent advances in the multidisciplinary management of coronary artery disease (CAD) have been significant. The assessment of patients before percutaneous coronary intervention is likely to change significantly. National compliance with clinical guidelines in the preprocedural assessment of myocardial ischemia shou...
6,794
Coronary angiography predicts improved outcome following cardiac arrest: propensity-adjusted analysis.
Determine if clinical parameters of resuscitated patients predict coronary angiography (CATH) performance and if receiving CATH after cardiac arrest is associated with outcome.</AbstractText>CATH is associated with survival in patients suffering out-of-hospital cardiac arrest (OHCA) from ventricular fibrillation or ven...
6,795
Acute myocardial infarction with changing axis deviation.
Changing axis deviation has been rarely reported also during atrial fibrillation or atrial flutter. Changing axis deviation has been rarely reported also during acute myocardial infarction associated with atrial fibrillation. Isolated left posterior hemiblock is a very rare finding but the evidence of transient right a...
6,796
Cerebral infarction and right ventricular noncompaction.
A 26-year-old man admitted with dysphasia and bilateral headache for three days. He had no known risk factors for stroke. Transthoracic two-dimensional echocardiography showed prominent trabeculations, with deep intertrabecular recesses in apex of the right ventricle. The multi-detector-row spiral cerebral computerized...
6,797
Post induction arrhythmia in a renal patient: an unexpected risk factor.
A 44 year-old woman was anaesthetised for a transplant nephrectomy. About 10 min after induction of anaesthesia she had several runs of ventricular tachycardia followed by ventricular fibrillation requiring 30 s of cardiopulmonary resuscitation, after which she reverted to sinus rhythm. Review of her chest X-ray, sugge...
6,798
Redox regulation, NF-kappaB, and atrial fibrillation.
Atrial fibrillation (AF) is the most common clinically encountered abnormal heart beat. It is associated with an increased risk of stroke and symptoms of heart failure. Current therapies are directed toward controlling the rate of ventricular activation and preventing strokes through anticoagulation. Attempts at suppre...
6,799
[Stroke and hypertension].
Arterial hypertension is the most important risk factor for stroke. Many interventional trials have unambiguously proven the benefit of antihypertensive therapy in both primary and secondary prevention for all age categories. No recommendation for any single antihypertensive substance for the primary prevention of stro...