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6,600 | Recurrence of ventricular arrhythmias in ischaemic secondary prevention implantable cardioverter defibrillator recipients: long-term follow-up of the Leiden out-of-hospital cardiac arrest study (LOHCAT). | To assess the long-term rate of mortality and the recurrence of potentially life-threatening ventricular arrhythmias in secondary prevention implantable cardioverter defibrillator (ICD) patients and to construct a model for baseline risk stratification.</AbstractText>Since 1996, all patients with ischaemic heart diseas... |
6,601 | Clinical study of 39 Chinese patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy. | There are few studies on the clinical profile of Chinese patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C). The purpose of this study was to describe the clinical characteristics of ARVD/C patients from China, particularly to define the features of electrocardiograph and treatment outcome... |
6,602 | Pacing threshold testing induced ventricular fibrillation following acute rate control of atrial fibrillation. | A properly placed stimulus on the T-wave during ventricular repolarization can result in ventricular fibrillation (VF). Initiation of VF with pacing on T-wave is a rare event with a few reported cases in the literature. We present a unique case of induced VF attributed to a pacing stimulus on T-wave during ventricular ... |
6,603 | The effects of left ventricular diastolic function on natriuretic peptide levels after cardioversion of atrial fibrillation. | Diastolic heart failure often coexists with atrial fibrillation (AF). Elevated plasma levels of natriuretic peptides are the left ventricular (LV) marker of diastolic dysfunction.</AbstractText>To evaluate the influence of sinus rhythm restoration on ANP and BNP levels in patients with normal and impaired LV diastolic ... |
6,604 | Ventricular pacing thresholds following high-energy implantable cardioverter defibrillator shocks in integrated bipolar defibrillation systems. | Increased ventricular pacing thresholds have been observed following monophasic implantable cardioverter defibrillator (ICD) shocks.</AbstractText>To examine changes following high-energy biphasic shocks delivered by integrated bipolar ICD systems.</AbstractText>Ten episodes of ventricular fibrillation (VF) were induce... |
6,605 | Role of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in the management of atrial fibrillation. | Atrial fibrillation (AF) is the most common clinical arrhythmia, and is difficult to treat. Current treatment strategies are far from optimal. Antiarrhythmic drug therapy to maintain sinus rhythm is limited by inadequate efficacy and potentially serious side effects. New areas of research include targeting the AF subst... |
6,606 | Complete recovery from aneurysmal subarachnoid hemorrhage associated with out-of-hospital cardiopulmonary arrest. | Out-of-hospital cardiopulmonary arrest (OHCPA) because of aneurysmal subarachnoid hemorrhage (SAH) is almost always fatal, because devastating SAH causes OHCPA and the brain damage is aggravated by OHCPA. We report a rare case of a 63-year-old female patient who survived SAH-induced ventricular fibrillation OHCPA witho... |
6,607 | Closed-chest experimental porcine model of acute myocardial infarction-reperfusion. | Progress in cardiovascular regenerative medicine research requires the availability of appropriate experimental animal models that are as close to humans as feasible. Our objective was to assess the validity of a porcine endovascular model of myocardial infarction and reperfusion.</AbstractText>Fifteen domestic pigs (L... |
6,608 | Prevalence and prediction of left atrial thrombus in patients with a recent cerebral ischemic event, who are in sinus rhythm: a single-center experience. | Left atrial thrombus (LAT) is frequently present in patients with cerebral ischemic events (CIE) who are in atrial fibrillation. The prevalence and predictor of LAT in patients who are in sinus rhythm (SR) is unclear.</AbstractText>To determine the prevalence and identify predictors of LAT formation in patients with CI... |
6,609 | [Circumferential pulmonary vein with additional linear ablation for persistent and permanent atrial]. | To investigate the safety and efficacy of circumferential pulmonary vein with additional linear ablation in treatment of persistent and permanent atrial fibrillation (AF), and to identify possible predictors of recurrence of AF.</AbstractText>The clinical data of 127 patients with persistent and permanent AF who had un... |
6,610 | Intravenous diltiazem is superior to intravenous amiodarone or digoxin for achieving ventricular rate control in patients with acute uncomplicated atrial fibrillation. | To compare the clinical efficacy of intravenous diltiazem, digoxin, and amiodarone for acute ventricular rate (VR) control in patients with acute symptomatic atrial fibrillation (AF) necessitating hospitalization.</AbstractText>Randomized control trial.</AbstractText>Acute emergency medical admission unit in a regional... |
6,611 | Hypothermia-treated cardiac arrest patients with good neurological outcome differ early in quantitative variables of EEG suppression and epileptiform activity. | To evaluate electroencephalogram-derived quantitative variables after out-of-hospital cardiac arrest.</AbstractText>Prospective study.</AbstractText>University hospital intensive care unit.</AbstractText>Thirty comatose adult patients resuscitated from a witnessed out-of-hospital ventricular fibrillation cardiac arrest... |
6,612 | Management of cardiac arrest caused by coronary artery spasm: epinephrine/adrenaline versus nitrates. | Cardiopulmonary resuscitation guidelines imply the use of epinephrine/adrenaline during cardiopulmonary arrest. However, in cardiac arrest situations resulting from coronary artery spasm (CAS), the use of epinephrine/adrenaline could be deleterious.</AbstractText>A 49-year-old patient underwent an emergency coronarogra... |
6,613 | Should aldosterone blockade be used beyond current indications in heart failure? | Aldosterone receptor antagonists (ARAs) are becoming important supplementary options in the pharmacologic treatment of congestive heart failure (CHF), and the indication for ARAs continues to grow. Aldosterone is a stimulator of myocardial fibrosis, causing progression of CHF and serving as an important factor in the p... |
6,614 | Intra-left atrial mechanical delay detected by tissue Doppler echocardiography can be a useful marker for paroxysmal atrial fibrillation. | There are some clinical and echocardiographic parameters to predict paroxysmal atrial fibrillation (PAF), but more sensitive predictors are needed. Tissue Doppler imaging may be a sensitive method for this purpose.</AbstractText>Thirty-four patients with PAF and 31 control subjects were studied. Time intervals from the... |
6,615 | Induced hypothermia after out-of-hospital cardiac arrest: one hospital's experience. | Induced mild hypothermia has been shown to reduce in-hospital mortality and to improve neurological outcome in patients who remain comatose after out-ofhospital cardiac arrest (OHCA). We conducted a retrospective audit to assess whether induced hypothermia had been successfully incorporated into routine care at our hos... |
6,616 | [Clinical analysis of inappropriate shock of implantable cardioverter defibrillators]. | Implantable cardioverter defibrillator (ICD) can effectively treat life-threatening ventricular arrhythmias. The most common side effect is inappropriate discharge. This study analyzes the incidence and causes of inappropriate discharges of ICD in our hospital.</AbstractText>Forty-three patients implanted with ICD in o... |
6,617 | [A clinical study on the diagnostic criteria of multiple organ dysfunction syndrome]. | To develop diagnostic criteria of multiple organ dysfunction syndrome (MODS) by a prospective and multi-center clinical investigation.</AbstractText>The data of 1087 MODS cases obtained from ICU of 37 hospitals from March 2002 to January 2005 in 11 provinces in China were analyzed in order to derive the diagnostic crit... |
6,618 | Lightning induced atrial fibrillation. | Atrial fibrillation (AF) is a common arrhythmia that occurs in paroxysmal and persistent forms. It occurs in varied situations but lightning induced AF is extremely rare. Here is a case which reverted to sinus rhythm spontaneously. This 37-year-old man without any underlying heart disease had new onset AF after being s... |
6,619 | Role of the His-Purkinje system in the genesis of cardiac arrhythmia. | Although a plethora of earlier studies focused on the histology and action potential characteristics of Purkinje fibers, only recently has the His-Purkinje system been found to play a major role in the genesis of cardiac arrhythmias. The anatomic complexity of the left ventricular conduction system appears to favor ree... |
6,620 | Spectral analysis of sustained and non-sustained ventricular fibrillation in patients with an implantable cardioverter-defibrillator. | The mechanisms responsible for the maintenance and termination of ventricular fibrillation (VF) are poorly understood. The aim of this study was to compare the spectral characteristics of the electrical signal during sustained and non-sustained VF in patients with an implantable cardioverter-defibrillator. The study in... |
6,621 | QRS duration and early hemodynamic instability after coronary revascularization surgery. | The duration of the QRS interval measured by ECG is a marker of ventricular dysfunction and indicates a poor prognosis. Its value in patients undergoing coronary revascularization surgery has not been established.</AbstractText>The study involved 203 consecutive patients (age 64+/-9 years, 74% male) scheduled for elect... |
6,622 | Atrial Fibrillation Complicating Congestive Heart Failure: Electrophysiological Aspects And Its Deleterious Effect On Cardiac Resynchronization Therapy. | More successful recognition and treatment of cardiovascular risk factors and diseases continues to decrease mortality and increase the proportion of elderly population. Therefore, there are more people with increased risk of developing heart failure and atrial fibrillation in the course of their lives. Atrial fibrillat... |
6,623 | Electrocardiographic abnormalities and ventricular tachyarrhythmias after myocardial infarction. | To assess the association of electrocardiographic repolarization and depolarization patterns to vulnerability to ventricular tachyarrhythmias.</AbstractText>In the present case-control study, a 12-lead ECG, signal-averaged ECG (SAECG), T-wave and QRS morphology, and T-wave alternans (TWA) were analyzed in post-MI patie... |
6,624 | Sustained ventricular arrhythmias in unstable angina patients: results of the ARIAM database. | The aim of this study was to investigate patients with unstable angina (UA) and the predictive factors of these arrhythmias and to determine whether this complication behaves as an independent variable with regard to mortality, increased length of stay in an ICU/CCU, and the performance of percutaneous coronary interve... |
6,625 | Carvedilol ameliorates the decreases in connexin 43 and ventricular fibrillation threshold in rats with myocardial infarction. | Connexin 43 (Cx43) is the most prominent connexin in the mammalian ventricular myocardium and forms gap junctions that are essential for normal conduction of action potential. Carvedilol, a nonselective beta-blocker, is widely used to prevent ventricular arrhythmias after myocardial infarction (MI). Here, we examined t... |
6,626 | Therapeutic effect of {beta}-adrenoceptor blockers using a mouse model of dilated cardiomyopathy with a troponin mutation. | Extensive clinical studies have demonstrated that beta-adrenoceptor blocking agents (beta-blockers) are beneficial in the treatment of chronic heart failure, which is due to various aetiologies, including idiopathic dilated cardiomyopathy (DCM) and ischaemic heart disease. However, little is known about the therapeutic... |
6,627 | [Management of atrial fibrillation in France: the observational FACTUEL study]. | To describe the management of patients with atrial fibrillation (AF) and to study consistency with guidelines on management of AF.</AbstractText>Observational study on a random sample of cardiologists from a French national database. Each cardiologist had to recruit the first five patients meeting inclusion criteria (p... |
6,628 | Vascular Ehlers-Danlos syndrome--all three coronary artery spontaneous dissections. | Vascular Ehlers-Danlos syndrome is an inherited connective-tissue disorder causing arterial and gastrointestinal fragility and spontaneous rupture of the large arteries, uterus, or bowel. Among arterial dissections and ruptures, spontaneous coronary artery dissection is extremely rare in this disorder. The specific the... |
6,629 | Utility of tissue Doppler imaging to predict exercise capacity in hypertrophic cardiomyopathy: comparison with B-type natriuretic peptide. | Recent reports suggest that left ventricular diastolic function assessed by tissue Doppler imaging (TDI) and plasma B-type natriuretic peptide (BNP) levels can relate to functional status in patients with hypertrophic cardiomyopathy (HCM). However, it is unclear which is more useful to predict the exercise capacity in ... |
6,630 | Recurrent ventricular fibrillation due to coronary artery spasm immediately after ascending aorta replacement. | Coronary artery spasm (CAS) is a dangerous complication during cardiac surgery, causing arduous weaning of extracorporeal circulation (ECC) and myocardial tissue loss with consequent left and right ventricular dysfunctions. We describe the case of a 67-year-old man with hypertension and smoking habit, with ECG evidence... |
6,631 | Cardiac resynchronization therapy with and without implantable cardioverter-defibrillator. | Cardiac resynchronization therapy (CRT) is recommended to reduce morbidity and mortality in patients with New York Heart Association class III/IV, who are symptomatic despite optimal medical therapy, and who had a reduced left ventricle (LV) ejection fraction and electrical dyssynchrony. The effects of CRT are reflecte... |
6,632 | Usefulness of cardiac magnetic resonance in assessing the risk of ventricular arrhythmias and sudden death in patients with hypertrophic cardiomyopathy. | To assess the relationship between cardiovascular magnetic resonance (CMR) parameters and both spontaneous ventricular tachycardia (VT) and risk of sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM) patients.</AbstractText>One hundred and eight consecutive HCM patients (mean age 42 +/- 15 years, 76% males)... |
6,633 | Presenting rhythm in sudden deaths temporally proximate to discharge of TASER conducted electrical weapons. | Sudden deaths proximate to use of conducted electrical weapons (CEWs) have been attributed to cardiac electrical stimulation. The rhythm in death caused by rapid, cardiac electrical stimulation usually is ventricular fibrillation (VF); electrical stimulation has not been reported to cause asystole or pulseless electric... |
6,634 | Usefulness of heart rate variability as a predictor of sudden cardiac death in muscular dystrophies. | Sudden cardiac death, or cardiac arrest, is a major health problem, causing about 166,200 deaths each year among adults in the United States. It may be caused by almost all known heart diseases. Most cardiac arrests occur when the diseased heart begins to exhibit rapid and/or chaotic activity, such as ventricular tachy... |
6,635 | Adenosine-induced ventricular asystole or rapid ventricular pacing to enhance three-dimensional rotational imaging during cardiac ablation procedures. | Rotational angiography with digital three-dimensional reconstruction (3DRA) allows per-procedural 3D imaging to facilitate cardiac ablation procedures. We developed a new approach that allows per-procedural 3D imaging of the atria and ventricles with a single C-arm rotation, combining higher 3D image quality with a low... |
6,636 | Regionalization of postcardiac arrest care. | To discuss the concept and implementation of regionalized postcardiac arrest care.</AbstractText>American Heart Association guidelines call for therapeutic hypothermia in patients who have return of spontaneous circulation but remain comatose after out-of-hospital cardiac arrest due to ventricular fibrillation. The rea... |
6,637 | Cardiopulmonary resuscitation in children. | To summarize recent advances in pediatric cardiopulmonary arrest prevention, resuscitation and postresuscitation management.</AbstractText>Pediatric cardiac arrest has traditionally been considered a futile medical condition with dismal outcomes. Data in the 21st century indicate that more than 25% of children treated ... |
6,638 | Paroxysmal atrial fibrillation after smokeless tobacco (Maras powder) use. | Use of cigarettes and smokeless tobacco is a considerable public health problem. In Turkey, a type of smokeless tobacco called Maras powder (MP) is widely used in the Southeastern region. We present a case of paroxysmal atrial fibrillation that was suspected to be caused by the use of MP, which has never previously bee... |
6,639 | Transmural optical measurements of Vm dynamics during long-duration ventricular fibrillation in canine hearts. | Knowledge of transmural V(m) changes is important for understanding the mechanism of long-duration ventricular fibrillation (LDVF).</AbstractText>The purpose of this study was to measure transmural V(m) changes during LDVF.</AbstractText>V(m) was recorded optically at up to 8 transmural points separated by 1.5 mm in th... |
6,640 | Mechanisms of recurrent ventricular fibrillation in a rabbit model of pacing-induced heart failure. | Successful defibrillation may be followed by recurrent spontaneous ventricular fibrillation (VF). The mechanisms of postshock spontaneous VF are unclear.</AbstractText>The purpose of this study was to determine the mechanisms of spontaneous VF after initial successful defibrillation in a rabbit model of heart failure (... |
6,641 | Left cardiac sympathetic denervation for the treatment of long QT syndrome and catecholaminergic polymorphic ventricular tachycardia using video-assisted thoracic surgery. | Long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT) are two of the most common, potentially lethal, cardiac channelopathies. Treatment strategies for the primary and secondary prevention of life-threatening polymorphic ventricular tachycardia/fibrillation include pharmacotherapy wit... |
6,642 | Angiotensin II receptor blockers in the prevention of atrial fibrillation. | Atrial fibrillation (AF) is the most common sustained arrhythmia. While antiarrhythmic agents and electrical cardioversion are highly effective in restoring sinus rhythm, the results obtained in prevention of recurrences are disappointing. Recently, angiotensin II has been recognized as a key factor in atrial structura... |
6,643 | Atrial-selective sodium channel block for the treatment of atrial fibrillation. | The pharmacological approach to therapy of atrial fibrillation (AF) is often associated with adverse effects resulting in the development of ventricular arrhythmias. As a consequence, much of the focus in recent years has been on development of atrial-selective agents. Atrial-selective sodium channel blockers have rece... |
6,644 | Amiodarone attenuates the proarrhythmic effects of dobutamine in patients with advanced congestive heart failure. | The long-term use of positive inotropic pharmaceuticals in patients suffering from end-stage congestive heart failure (CHF) has been associated with increased mortality, presumed to be due to proarrhythmia. Oral amiodarone combined with intermittent dobutamine infusions (IDI), on the other hand, has been shown to incre... |
6,645 | Comparison of outcomes of minimally invasive mitral valve surgery for posterior, anterior and bileaflet prolapse. | We sought to compare the outcomes of minimally invasive mitral valve (MV) surgery for anterior (anterior mitral leaflet, AML), posterior (posterior mitral leaflet, PML) or bileaflet (BL) MV prolapse.</AbstractText>Between August 1999 and December 2007, 1230 patients who presented with isolated AML (n=156, 12.7%), isola... |
6,646 | The effect of biventricular pacing after coronary artery bypass grafting: a prospective randomized trial of different pacing modes in patients with reduced left ventricular function. | Biventricular pacing acutely improves left ventricular function in patients with heart failure and left ventricular dyssynchrony. Pressure-volume loop analysis has shown acute perioperative hemodynamic benefits of biventricular pacing immediately after weaning from cardiopulmonary bypass in patients undergoing coronary... |
6,647 | Subclinical hypothyroidism might increase the risk of transient atrial fibrillation after coronary artery bypass grafting. | Some studies have proposed that subclinical hypothyroidism (SCH) has adverse effects on the cardiovascular system, but little is known about the effect on patients undergoing cardiovascular operations. We examined the influence of preoperative SCH on postoperative outcome in patients undergoing coronary artery bypass g... |
6,648 | The Toronto Root bioprosthesis: midterm results in 186 patients. | The Toronto Root bioprosthesis with BiLinx anticalcification treatment (St. Jude Medical, St. Paul, MN) was introduced into clinical practice in 2001, mainly for patients with aortic valve disease and additional pathology of the aorta. Patients included in the initial clinical study with core laboratory data evaluation... |
6,649 | Relation of immediate decrease in ventricular septal strain after alcohol septal ablation for obstructive hypertrophic cardiomyopathy to long-term reduction in left ventricular outflow tract pressure gradient. | Alcohol septal ablation (ASA) aims to decrease left ventricular outflow tract (LVOT) obstruction in patients with obstructive hypertrophic cardiomyopathy (HC). To date, no diagnostic variables at baseline are available to predict long-term success of the procedure. We hypothesized that an immediate decrease in septal l... |
6,650 | [Morphological prerequisites of heart ventricles fibrillation in sudden cardiac death]. | We studied morphological changes in the myocardium and content of glucose, magnesium, calcium, sodium in pericardial fluid of victims of out of hospital sudden death due to acute coronary insufficiency and prenecrotic stage of myocardial infarction. We established that both in regions of ischemic injury appearing as II... |
6,651 | Impact of atrial antitachycardia pacing and atrial pace prevention therapies on atrial fibrillation burden over long-term follow-up. | Selective atrial pacing algorithms have been developed for prevention of atrial tachycardia/atrial fibrillation (AT/AF). Although short-term studies have shown modest to minimal incremental benefit of these algorithms compared with conventional dual-chamber (DDD/R) pacing for prevention of AT/AF, the long-term effects ... |
6,652 | Selecting the transthoracic defibrillation shock directional vector based on VF amplitude improves shock success. | Termination of ventricular fibrillation (VF) by a defibrillating shock is more likely to occur when the VF amplitude is larger. We hypothesized that a defibrillation shock would achieve higher success if the shock vector was oriented along the largest of the VF amplitudes measured simultaneously in 3 orthogonal ECG lea... |
6,653 | Atrial fibrillation and the risk of death in patients with heart failure: a literature-based meta-analysis. | Heart failure (HF) and atrial fibrillation (AF) are common, associated with significant morbidity and mortality, and frequently coexist. It is uncertain from published data if the presence of AF in patients with HF is associated with an incremental adverse outcome. The aim of this study was to combine the results of al... |
6,654 | Factors affecting immediate changes in cardiac output following balloon mitral valvulotomy: the role of pulmonary hemodynamics. | The study aim was to investigate the factors that affect changes in cardiac output (CO) following balloon mitral valvulotomy (BMV), which at present are essentially unknown.</AbstractText>Among a total of 168 patients, clinical, echocardiographic and hemodynamic data before and after BMV were compared between patients ... |
6,655 | Cardiac amyloidosis treated with an implantable cardioverter defibrillator and subcutaneous array lead system: report of a case and literature review. | Preventing ventricular arrhythmias in patients with cardiac amyloidosis is challenging since the amyloid protein deposition in the myocardium may interfere with the normal cardiac electric excitation. Most of these patients succumb to either progressive congestive heart failure, or sudden cardiac death (SCD). Implantab... |
6,656 | Ischemia and reperfusion-induced arrhythmias: role of hyperoxic preconditioning. | Hyperoxic preconditioning is known to protect the heart against necrosis and contractile dysfunction, but protection against arrhythmias has not been well characterized.</AbstractText>The authors hypothesized that pre-exposure to normobaric hyperoxia (H) reduces ischemia and reperfusion-induced arrhythmias in isolated ... |
6,657 | Initial defibrillation versus initial chest compression in a 4-minute ventricular fibrillation canine model of cardiac arrest. | Previous laboratory and clinical studies have demonstrated that chest compression preceding defibrillation in prolonged ventricular fibrillation (VF) increases the likelihood of successful cardiac resuscitation. The lower limit of VF duration when preshock chest compression provides no benefit has not been specifically... |
6,658 | Contemporary analysis of predictors and etiology of ventricular fibrillation during diagnostic coronary angiography. | To assess the incidence, investigate the predictors and analyze the causes of ventricular fibrillation (VF) during coronary angiography (CA) on the condition of current techniques.</AbstractText>From April 2004 to January 2007, a total 22,254 patients (27,798 procedures) received CA procedures in our center; 27 patient... |
6,659 | C-type natriuretic peptide production by the human kidney is blunted in chronic heart failure. | CNP (C-type natriuretic peptide) is a vasodilatory peptide produced by vascular endothelium and the human heart with a short half-life. CNP has been identified within the human kidney; however, few results are available on whether the human kidney is a systemic source of CNP. The aim of the present study was to establi... |
6,660 | Idiopathic ventricular fibrillation associated with J wave and early repolarization: a really benign electrocardiographic sign? | Evaluation of: Sudden cardiac arrest associated with early repolarization. Haiissaguerre M, Derval N, Saccher F et al.: N. Engl. J. Med. 358, 2016-2023 (2008). In patients with idiopathic ventricular fibrillation, several kinds of electrocardiographic findings have been reported. Brugada electrocardiogram (ECG), a cove... |
6,661 | Genetic and clinical profile of Indian patients of idiopathic restrictive cardiomyopathy with and without hypertrophy. | Both idiopathic restrictive cardiomyopathy (IRCM) and hypertrophic cardiomyopathy (HCM) are part of the same disease spectrum and are due to sarcomeric gene mutations. A patient with restrictive physiology without left ventricular hypertrophy (LVH) would be diagnosed as IRCM, while one with LVH would be diagnosed as HC... |
6,662 | Prediction of countershock success: a comparison of autoregressive and fast fourier transformed spectral estimators. | Spectral analysis of the ventricular fibrillation (VF) ECG has been used for predicting countershock success, where the Fast Fourier Transformation (FFT) is the standard spectral estimator. Autoregressive (AR) spectral estimation should compute the spectrum with less computation time. This study compares the predictive... |
6,663 | Are our medical graduates in New Zealand safe and accurate in ECG interpretation? | We aimed to assess the skills of final year medical students and resident medical officers in recognising and interpreting important common or life-threatening abnormalities in the electrocardiogram (ECG).</AbstractText>102 participants at two study sites (52 of whom were final year medical students) attempted to deter... |
6,664 | Electrical cardioversion. | External electrical cardioversion was first performed in the 1950s. Urgent or elective cardioversions have specific advantages, such as termination of atrial and ventricular tachycardia and recovery of sinus rhythm. Electrical cardioversion is life-saving when applied in urgent circumstances. The succcess rate is incre... |
6,665 | Right ventricular pacing is associated with impaired overall survival, but not with an increased incidence of ventricular tachyarrhythmias in routine cardioverter/defibrillator recipients with reservedly programmed pacing. | Data from previous defibrillator studies raised concern about right ventricular pacing (RVP) promoting heart failure progression and mortality in implantable cardioverter/defibrillator (ICD) patients. The present observational study re-examined the association of RVP, survival, and ventricular tachyarrhythmias/ventricu... |
6,666 | The Medical ANtiarrhythmic Treatment or Radiofrequency Ablation in Paroxysmal Atrial Fibrillation (MANTRA-PAF) trial: clinical rationale, study design, and implementation. | No large randomized multicentre trial has evaluated the efficacy of radiofrequency ablation (RFA) vs. anti-arrhythmic drug (AAD) therapy as a first-line treatment of paroxysmal atrial fibrillation (AF).</AbstractText>The Medical ANtiarrhythmic Treatment or Radiofrequency Ablation (MANTRA-PAF) trial is a randomized, con... |
6,667 | A fast-growing obstructive left atrial intramural hematoma causing acute prolonged chest pain. | A 74-year-old woman was at the emergency department for acute chest pain, dyspnea and severe transient hypotension. History was arterial hypertension and external electrical cardioversion (EEC) for persistent atrial fibrillation (AF) 8 days before admission. At that time echocardiography was normal. The patient underwe... |
6,668 | Recurrence of ventricular tachycardia degeneration by low-energy implantable cardioverter-defibrillator shocks: a case report. | Despite their proven efficacy at reducing mortality in selected patients, implantable cardioverter-defibrillators have some proarrhythmic effects. In this report, we present a case of a patient with recurrent ventricular tachycardia degeneration to ventricular fibrillation by appropriate low-energy implantable cardiove... |
6,669 | Intracoronary acid infusion as an alternative to ischemic postconditioning in pigs. | Previous studies suggested that prolongation of acidosis during reperfusion is protective and may be an important mechanism of postconditioning protection. The aim of this study was to analyze the therapeutic value of this intervention during in vivo coronary reperfusion, and to compare it with ischemic postconditionin... |
6,670 | Sympathetic excitation during exercise as a cause of attenuated heart rate recovery in patients with myocardial infarction. | Heart rate recovery (HRR) after exercise is known as a predictor of cardiac death in patients with heart disease. The mechanism is not fully understood, although a parasympathetic mechanism has been reported. To elucidate the factors that influence HRR, we evaluated the relationship of HRR with exercise performance and... |
6,671 | Pharmacological characteristics and clinical applications of K201. | K201 is a 1,4-benzothiazepine derivative that is a promising new drug with a strong cardioprotective effect. We initially discovered K201 as an effective suppressant of sudden cardiac cell death due to calcium overload. K201 is a non-specific blocker of sodium, potassium and calcium channels, and its cardioprotective e... |
6,672 | Novel approaches for pharmacological management of atrial fibrillation. | In the light of the progressively increasing prevalence of atrial fibrillation (AF), medical awareness of the need to develop improved therapeutic approaches for the arrhythmia has also risen over the last decade. AF reduces quality of life and is associated with increased morbidity and mortality. Despite several setba... |
6,673 | Assessment of atrial electromechanical coupling characteristics in patients with ankylosing spondylitis. | The aim of this study was to evaluate atrial conduction abnormalities obtained by Doppler tissue imaging (DTI) and electrocardiogram analysis in ankylosing spondylitis (AS) patients.</AbstractText>A total of 40 patients with AS (22 males /18 females, 37.82 +/- 10.22 years), and 42 controls (22 males/20 females, 35.74 +... |
6,674 | Atrioventricular node ablation is not a prerequisite for cardiac resynchronization therapy in patients with chronic atrial fibrillation. | In drug-refractory heart failure, cardiac resynchronization therapy (CRT) is an established method in patients with sinus rhythm, severe reduced ejection fraction and broad QRS. Heart failure is known as a predisposition for atrial fibrillation (AF). However, the putative impact of atrioventricular node (AVN) ablation ... |
6,675 | Cardiac resynchronization therapy in heart failure patients: an update. | Heart failure continues to be a major public health problem with high morbidity and mortality rates, despite the advances in medical treatment. Advanced heart failure patients have severe persistent symptoms and a poor quality of life. Cardiac resynchronization therapy (CRT), an invasive therapy which involves synchron... |
6,676 | Candesartan cilexetil in the treatment of chronic heart failure. | The prevalence of heart failure is ever increasing around the world, particularly due to aging populations. Despite improvements in treatment over the last 20 years, the prognosis for heart failure remains poor. Among the treatments recommended for chronic heart failure, angiotensin-converting enzyme (ACE) inhibitors a... |
6,677 | Experimental evaluation of the JenaClip transcatheter aortic valve. | Transcatheter techniques of aortic valve replacement are a treatment option for valvular heart disease in high-risk surgical candidates. We evaluated a self-expanding valve system with a novel mechanism of fixation in an experimental setting in an acute animal model and ex vivo in aortic root specimens.</AbstractText>A... |
6,678 | Interventional treatment of structural heart disease. | Transcatheter therapy of structural heart disease is advancing rapidly. Due to the less invasive approach, transcatheter techniques have replaced surgery as standard procedure for atrial septal defect and patent foramen ovale closure. Evolving interventional techniques allow treatment of paravalvular leaks, ventricular... |
6,679 | Multivessel spontaneous coronary artery dissection in a postpartum woman treated with multiple drug-eluting stents. | Multivessel spontaneous coronary artery dissection is a very rare cause of myocardial ischemia. Its optimal treatment is not yet well defined and is usually tailored to clinical features. We report a case of a postpartum woman with multivessel spontaneous coronary artery dissection and acute myocardial infarction, in w... |
6,680 | One-year follow-up and convalescence evaluated by nuclear medicine studies and 24-hour holter electrocardiogram in 11 patients with myocardial injury due to a blunt chest trauma. | There are few reports on long-term convalescence with regard to cardiac injury caused by blunt chest trauma. Nuclear medicine study of the heart (NMSH) in the early stages of injury is reportedly superior to detect the correlation between injury and fatal arrhythmia. Therefore, we prospectively performed NMSH and Holte... |
6,681 | Mitochondrial benzodiazepine receptors mediate cardioprotection of estrogen against ischemic ventricular fibrillation. | The cardioprotective effects of estrogen remain controversial in clinical practice. Previous reports have shown that cardioprotective mechanisms converge on the mitochondria, but the role of mitochondria in estrogen's actions on cardiac arrhythmias is unclear. Here, we report that stimulation or inhibition of mitochond... |
6,682 | [Potentially lethal cardiac side effects caused by psychiatric drugs]. | The objective of this article is to analyze some of the potentially lethal cardiac side effects of psychiatric drugs and to contribute with the necessary instruments to diagnose and treat them properly. Prolongation of the QT interval caused by most of antipsychotics is discussed, focusing on those drugs with greater r... |
6,683 | Defibrillation probability and impedance change between shocks during resuscitation from out-of-hospital cardiac arrest. | Technical data now gathered by automated external defibrillators (AEDs) allows closer evaluation of the behavior of defibrillation shocks administered during out-of-hospital cardiac arrest. We analyzed technical data from a large case series to evaluate the change in transthoracic impedance between shocks, and to asses... |
6,684 | The fentanyl/etomidate-anaesthetised beagle (FEAB) dog: a versatile in vivo model in cardiovascular safety research. | The purpose of conducting cardiovascular safety pharmacology studies is to investigate the pharmacological profiles of new molecular entities (NMEs) and provide data that can be used for optimization of a possible new drug, and help make a selection of NMEs for clinical development. An anaesthetised dog preparation has... |
6,685 | Dilated cardiomyopathy with short QT interval: is it a new clinical entity? | Short QT syndrome is a rare autosomal dominant channelopathy of structurally normal hearts characterized by atrial fibrillation, ventricular arrhythmias, and sudden cardiac death. We report a case having short QT, dilated ventricles, and severe ventricular dysfunction, an unreported association so far. |
6,686 | A shock lead intentionally placed in the left ventricle. | The implantable cardioverter defibrillator is effective in reducing sudden cardiac death in high-risk patients. The implantation procedure is usually simple; however, in those patients who have congenital heart disease (CHD) placement of leads can be a challenge. In this report we present a patient with CHD where due t... |
6,687 | Use of triple-site ventricular pacing in a patient with severe congestive heart failure and atrial fibrillation. | Cardiac resynchronization therapy (CRT) has become an accepted treatment for selected patients with drug-resistant heart failure. Data for patients in atrial fibrillation (AF) remains limited but suggests benefit in these patients too. We report the case of an 82-year-old patient with heart failure, VVIR permanent pace... |
6,688 | Mast cell degranulation--a mechanism for the anti-arrhythmic effect of endothelin-1? | The aim of this study was to investigate whether the previously reported anti-arrhythmic effect of endothelin-1 (ET-1) is mediated by degranulation of cardiac mast cells prior to myocardial ischaemia.</AbstractText>Male Sprague-Dawley rats received either ET-1 (1.6 nmolxkg(-1)) in the presence or absence of disodium cr... |
6,689 | Quinidine for pharmacological cardioversion of atrial fibrillation: a retrospective analysis in 501 consecutive patients. | Although quinidine has been used to terminate atrial fibrillation (AFib) for a long time, it has been recently classified to be used as a third-line-drug for cardioversion. However, these recommendations are based on a few small studies, and there are no data available of a larger modern patient population undergoing p... |
6,690 | Incidence of and outcomes associated with ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention. | The incidence and timing of sustained ventricular tachycardia or fibrillation (VT/VF) and its impact on outcomes in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) are poorly understood.</AbstractText>To evaluate the association of sustained VT/VF and... |
6,691 | [Inherited cardiac diseases caused by Nav1.5 sodium channel mutations]. | Contraction of the heart is achieved through a delicately regulated conduction of electrical impulses. A pivotal element in the impulse propagation is the depolarising sodium current responsible for the initial depolarisation of the cardiomyocytes. Recent research has shown that mutations in the gene encoding the cardi... |
6,692 | Intracardiac thrombosis and anticoagulation therapy in cardiac amyloidosis. | Primary amyloidosis has a poor prognosis as a result of frequent cardiac involvement. We recently reported a high prevalence of intracardiac thrombus in cardiac amyloid patients at autopsy. However, neither the prevalence nor the effect of anticoagulation on intracardiac thrombus has been evaluated antemortem.</Abstrac... |
6,693 | Improved patient survival using a modified resuscitation protocol for out-of-hospital cardiac arrest. | Cardiac arrest continues to have poor survival in the United States. Recent studies have questioned current practice in resuscitation. Our emergency medical services system made significant changes to the adult cardiac arrest resuscitation protocol, including minimizing chest compression interruptions, increasing the r... |
6,694 | Revolving back to the basics in cardiopulmonary resuscitation. | Since the 1970s, most of the research and debate regarding interventions for cardiopulmonary arrest have focused on advanced life support (ALS) therapies and early defibrillation strategies. During the past decade, however, international guidelines for cardiopulmonary resuscitation (CPR) have not only emphasized the co... |
6,695 | Morphology discrimination criterion wavelet improves rhythm discrimination in single-chamber implantable cardioverter-defibrillators: Spanish Register of morphology discrimination criterion wavelet (REMEDIO). | Implantable cardioverter defibrillators (ICDs) are increasingly being used for treatment of ventricular tachycardia (VT)/fibrillation. Inappropriate therapy delivery remains the most frequent complication in patients with ICDs, resulting in psychological distress, proarrhythmia, and battery life reduction. We aim to de... |
6,696 | Intraprocedural reconstruction of the left atrium and pulmonary veins as a single navigation tool for ablation of atrial fibrillation: a feasibility, efficacy, and safety study. | Pulmonary vein (PV) isolation is a technically challenging intervention. For this reason, integration of three-dimensional imaging with computed tomography (CT) or magnetic resonance imaging (MRI) in order to enhance effectiveness and safety has been widely adopted. A novel imaging approach--intraprocedural rotational ... |
6,697 | Long-term prognosis after out-of-hospital cardiac arrest with/without ST elevation myocardial infarction. | To describe the 3-year survival of patients after out-of-hospital cardiac arrest (OHCA) taking into account the presence of ST-segment elevation myocardial infarction (STEMI) and evaluating prognostic factors associated with pre-hospital and hospital care.</AbstractText>Over a period of 29 months and with the aid of a ... |
6,698 | [Postpartum hemorrhage: an observational study of 21,726 deliveries in 28 months]. | To describe the management of severe postpartum hemorrhage.</AbstractText>Prospective observational study from July 2005 to November 2007 in women who were admitted to the recovery unit of a tertiary referral hospital due to postpartum hemorrhage. We analyzed incidence, prevalence, morbidity, mortality, and associated ... |
6,699 | Augmentation index is associated with B-type natriuretic peptide in patients with paroxysmal atrial fibrillation. | B-type natriuretic peptide (BNP) levels have been shown to be elevated in patients with paroxysmal atrial fibrillation (PAF); however, the underlying mechanisms have not been fully elucidated. Earlier, we reported that an increase in the augmentation index (AI), which is an index of wave reflection and arterial stiffne... |
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