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7,100
Junior physician skill and behaviour in resuscitation: a simulation study.
Physicians are expected to manage their role as teamleader during resuscitation. During inter-hospital transfer the physician has the highest medical credentials on a small team. The aim of this study was to describe physician behaviour as teamleaders in a simulated cardiac arrest during inter-hospital transfer. Our go...
7,101
Adaptive neuro-fuzzy inference system for classification of ECG signals using Lyapunov exponents.
This paper describes the application of adaptive neuro-fuzzy inference system (ANFIS) model for classification of electrocardiogram (ECG) signals. Decision making was performed in two stages: feature extraction by computation of Lyapunov exponents and classification by the ANFIS trained with the backpropagation gradien...
7,102
Prevalence of left atrial appendage pseudothrombus filling defects in patients with atrial fibrillation undergoing coronary computed tomography angiography.
Previous reports have shown that computed tomography (CT) is a useful, noninvasive test for detecting atrial thrombi. However, blood stasis in the left atrial appendage (LAA) of patients with atrial fibrillation (AF) may be a common cause for false-positive results.</AbstractText>We retrospectively evaluated the preval...
7,103
Surgical treatment of chronic atrial fibrillation with conventional electrocautery in mitral valve surgery.
To evaluate the results of the surgical treatment of atrial fibrillation for ablation of the posterior left atrial wall using electrocautery in mitral valve surgery.</AbstractText>From May 2004 to December 2006, 23 patients underwent surgical correction of mitral valve disease and treatment of atrial fibrillation using...
7,104
Progressing from initial non-shockable rhythms to a shockable rhythm is associated with improved outcome after out-of-hospital cardiac arrest.
Cardiac arrest patients with initial non-shockable rhythm progressing to shockable rhythm have been reported to have inferior outcome to those remaining non-shockable. We wanted to confirm this observation in our prospectively collected database, and assess whether differences in cardiopulmonary resuscitation (CPR) qua...
7,105
A national resuscitation registry of out-of-hospital cardiac arrest in Germany-a pilot study.
Survival rate after out-of-hospital cardiac arrest (OHCA) has not significantly increased over the last decade. However, survival rate has been used as a quality benchmark for many emergency medical services. A uniform resuscitation registry may be advantageous for quality management of cardiopulmonary resuscitation (C...
7,106
Half of the patients with chest pain that are urgently referred are transported in unsafe conditions.
Patients with an acute coronary syndrome should be referred to hospital urgently to start reperfusion therapy as soon as possible. Owing to the risks of ventricular fibrillation and pulseless ventricular tachycardia, urgent transport should be organized under safe conditions, that is, with a defibrillator at hand.</Abs...
7,107
Catheter ablation for patients with ventricular fibrillation.
Ventricular fibrillation is a challenging arrhythmia for physicians, with only a limited number of treatment options available. Implantable cardioverter defibrillator therapy is the treatment of choice for patients for both primary and secondary prevention with the role of antiarrhythmic therapy aimed at reducing the n...
7,108
Atrial-selective pharmacological therapy for atrial fibrillation: hype or hope?
Rhythm control remains of therapeutic value for many atrial fibrillation patients despite no evidence of survival benefit. This lack of benefit may relate to side effects of conventional antiarrhythmic drugs. The introduction of novel agents was a logical consequence.</AbstractText>Novel antiarrhythmics are currently b...
7,109
Taser X26 discharges in swine: ventricular rhythm capture is dependent on discharge vector.
Data from our previous studies indicate that Taser X26 stun devices can acutely alter cardiac function in swine. We hypothesized that most transcardiac discharge vectors would capture ventricular rhythm, but that other vectors, not traversing the heart, would fail to capture the ventricular rhythm.</AbstractText>Using ...
7,110
The efficacy of rewarming with a portable and percutaneous cardiopulmonary bypass system in accidental deep hypothermia patients with hemodynamic instability.
Accidental deep hypothermia (ADH)--a condition in which the core body temperature is less than 28 degrees C--is a medical emergency; the mortality rates for ADH remain high. The efficacy of cardiopulmonary bypass (CPB) rewarming has been proved in ADH patients with cardiopulmonary arrest; however, its efficacy in the A...
7,111
[Spatiotemporal characteristics of activation of the heart of hibernating and non-hibernating mammals during hypothermia].
The heart of hibernating mammals is known to demonstrate the nature\'s model of resistance to rhythm disturbances, including ventricular arrhythmias, during hypothermia. However, electrophysiological mechanism of this phenomenon is not completely understood. Using optical mapping technique with voltage-sensitive dye di...
7,112
Long-term electrocardiographic follow-up from childhood of an adult patient with Brugada syndrome associated with sick sinus syndrome.
We had the unique opportunity of following the electrocardiographic (ECG) course of a 13-year-old male with sinus dysfunction and atrial flutter who subsequently developed a Brugada-type ECG pattern associated with sick sinus syndrome at 25 years old. Family history showed that the patient's mother and maternal grandfa...
7,113
Dynamic change in ST-segment and spontaneous occurrence of ventricular fibrillation in Brugada syndrome with a novel nonsense mutation in the SCN5A gene during long-term follow-up.
A 67-year-old male underwent genetic testing under the diagnosis of Brugada syndrome because of recurrent ventricular fibrillation with coincident ST-segment elevation in either right precordial, inferior leads or both since the age of 55 years. Screening of gene mutations using denaturing high-performance liquid chrom...
7,114
Action potential alternans in the right ventricular outflow tract in a patient with asymptomatic Brugada syndrome.
A 71-year-old man with frequent ventricular premature contractions after right hip joint surgery was referred to the Cardiology Division. Twelve-lead ECG showed type II Brugada-type ECG and signal-averaged ECG showed positive ventricular late potentials. The 12-lead ECG changed to type I Brugada-type after administrati...
7,115
Idiopathic ventricular fibrillation characterized by spatial heterogeneity of action potential duration and its restitution kinetics.
A 44-year-old man who had suffered multiple episodes of syncope presented with ventricular fibrillation (VF). Structural heart disease was ruled out. Programmed stimulation induced VF at the right ventricular apex (RVA) but not at the outflow tract (RVOT). Monophasic action potential duration (MAPD) at a basic cycle le...
7,116
Identification of the gene causing long QT syndrome in an Israeli family.
Long QT syndrome is an inherited cardiac disease, associated with malignant arrhythmias and sudden cardiac death.</AbstractText>To map and identify the gene responsible for LQTS in an Israeli family.</AbstractText>A large family was screened for LQTS after one of them was successfully resuscitated from ventricular fibr...
7,117
[Ebstein's anomaly as a cause of paroxysmal atrial fibrillation].
Ebstein's anomaly is characterized by a displacement of the tricuspid valve toward apex, because of anomalous attachment of the tricuspid leaflets. There are type B of Wolff-Parkinson-White (WPW) syndrome and paroxysmal arrhythmias in more than a half of all patients.</AbstractText>We presented a female, 32-year old, w...
7,118
Outcomes after heart valve replacement surgery at the Cardiovascular Center of Puerto Rico and the Caribbean.
Heart valve surgery is the second most common type of cardiac surgery. However, there is limited information about the outcomes associated to these types of surgeries.</AbstractText>A retrospective review was performed in 91 Puerto Rican patients who underwent elective heart valve replacement surgery at the Cardiovascu...
7,119
[Training in cardiopulmonary resuscitation: impact on the theoretical knowledge of nurses].
This cross-sectional study aimed at evaluating the knowledge of nurses on cardiopulmonary resuscitation (CPR) as a function of the time elapsed since training was concluded. The study was performed in a general hospital in Porto Alegre, Rio Grande do Sul, during July and August, 2005. Nurses were assigned to groups 1 (...
7,120
Delayed cardiac perforation by defibrillator lead placed in the right ventricular outflow tract resulting in massive pericardial effusion.
A 76-year-old man received a dual-chamber implantable cardioverter defibrillator (ICD), with the defibrillator lead positioned within the right ventricular outflow tract. The lead parameters at the time of implantation were satisfactory and the post-procedure chest X-ray showed the leads were in place. The patient was ...
7,121
Does atrial fibrillation beget ventricular fibrillation in patients with acute myocardial infarction?
Atrial fibrillation (AF) is associated with increased mortality and a higher complication rate postmyocardial infarction (MI), but the exact mechanisms are unknown. We investigated whether AF predisposes to ventricular arrhythmia in postmyocardial infarct patients, thereby accounting for increased mortality.</AbstractT...
7,122
Ablation of polymorphic ventricular tachycardias in patients with structural heart disease.
Monomorphic ventricular premature beats (VPB) originating from the Purkinje network can induce polymorphic ventricular tachycardia (PMVT) and ventricular fibrillation (VF) storm. We hereby report the results of targeted ablation to treat PMVT/VF storms initiated by monomorphic VPB in seven patients with structural hear...
7,123
[The effects of modulation of cardiac metabolism and antioxidant state on myocardial ischemia-reperfusion injury].
The effects of mexicor (ethylmethylhydroxypyridine succinate) at doses of 50 and 100 mg/kg on myocardial infarct size, serum levels of myocardial markers, and severity of ischemia- and reperfusion-induced arrhythmias were studied in the rat model of myocardial ischemia-reperfusion injury. It was shown that pre-ischemic...
7,124
Feasibility and safety of remote-controlled magnetic navigation for ablation of atrial fibrillation.
Radiofrequency ablation for atrial fibrillation (AF) involves complex catheter manipulation resulting in prolonged procedure time and fluoroscopy exposure. Remote magnetic navigation (RMN) represents a novel approach toward improving the ability to perform complex ablation. Forty patients underwent ablation for AF, 20 ...
7,125
Thirty-year trends (1975-2005) in the magnitude, patient characteristics, and hospital outcomes of patients with acute myocardial infarction complicated by ventricular fibrillation.
Limited contemporary data are available describing the incidence rates, hospital prognosis, and factors associated with the occurrence of ventricular fibrillation (VF) in patients hospitalized with acute myocardial infarction (AMI). The objectives of our study were to examine 3-decade-long trends (1975 to 2005) in the ...
7,126
Magnitude and prognosis associated with ventricular arrhythmias in patients hospitalized with acute coronary syndromes (from the GRACE Registry).
The incidence, prognosis, and factors associated with ventricular arrhythmia (VA) in acute coronary syndrome are unknown. We sought to examine the magnitude, predictors, and outcomes of in-hospital VA in patients with acute coronary syndrome. The population comprised 52,380 patients enrolled in the Global Registry of A...
7,127
Rationale, design, and baseline characteristics of a Program to Assess and Review Trending INformation and Evaluate CorRelation to Symptoms in Patients with Heart Failure (PARTNERS HF).
Heart failure (HF) is a common medical problem with significant morbidity and mortality. Recently, device-based therapy, cardiac resynchronization therapy (CRT), implantable cardioverter-defibrillators (ICDs), and combined CRT and ICD have become established therapies in patients with HF receiving standard medical ther...
7,128
A computational study of mother rotor VF in the human ventricles.
Sudden cardiac death is one of the major causes of death in the industrialized world. It is most often caused by a cardiac arrhythmia called ventricular fibrillation (VF). Despite its large social and economical impact, the mechanisms for VF in the human heart yet remain to be identified. Two of the most frequently dis...
7,129
Treatment of atrial fibrillation.
Atrial fibrillation (AF) is the most common, sustained rhythm disturbance. The prevalence of AF is increasing as people live longer. Common conditions such as hypertension and ischaemic heart disease play an important role in the development of AF. The presence of AF is associated with increased morbidity and mortality...
7,130
Chest compression quality variables influencing the temporal development of ROSC-predictors calculated from the ECG during VF.
Predictive measures that reflect the probability of return of spontaneous circulation (ROSC) if the patient is defibrillated can be calculated from the electrocardiogram during ventricular fibrillation (VF) and ventricular tachycardia (VT). It has not been studied how the quality of chest compressions affect the develo...
7,131
Short QT syndrome. Update on a recent entity.
The short QT syndrome, a recently discovered ion channel disorder, combines shortened repolarization, a predisposition to atrial and ventricular fibrillatory arrhythmias, and a risk of sudden death. Few cases have been reported, but the prevalence may be underestimated. This syndrome might account for some cases of une...
7,132
Defibrillation and the quality of layperson cardiopulmonary resuscitation-dispatcher assistance or training?
To examine whether basic life support-defibrillation (BLS-D) training of laypersons enhances the speed of defibrillation and the quality of cardiopulmonary resuscitation (CPR) during a simulated ventricular fibrillation scenario compared with a situation where the care provider has no previous BLS-D training but receiv...
7,133
Brugada syndrome unmasked by sodium channel blockade.
We report the case of a 29-year-old male suffering from recurrent syncope and palpitations. He had a structurally normal heart and his baseline electrocardiogram was normal. His electrophysiologic study revealed an inducible, nonsustained polymorphic ventricular tachycardia on programmed electrical stimulation. With th...
7,134
Ventricular fibrillation triggered by marijuana use in a patient with ischemic cardiomyopathy: a case report.
A 60-year-old man presented to the emergency department with a left eye orbital rupture sustained during a fall due to syncope shortly after smoking more than his usual amount of marijuana.</AbstractText>The patient reported experiencing a shock from his implantable cardioverter-defibrillator (ICD) device prior to the ...
7,135
Anomalous coronary artery from the wrong sinus in a 15-year-old boy.
Congenital coronary artery anomalies are a well-recognized risk factor for sudden cardiac death in children as well as young adults, mostly during or immediately after intense exertion on the athletic field. Because these malformations are amenable to surgical treatment, timely identification is crucial. Unfortunately,...
7,136
A case study in therapeutic hypothermia treatment post-cardiac arrest in a 56-year-old male.
Cellular damage related to reperfusion injury after successful resuscitation may lead to increased morbidity and mortality in survivors of cardiac arrest. Therapeutic hypothermia to decrease the effects of reperfusion injury has demonstrated improved neurologic outcomes for patients who have experienced out-of-hospital...
7,137
[The progress of therapeutic hypothermia for patients with comatose survivors of out-of-hospital cardiac arrest this century].
Two randomized clinical trials were reported using mild therapeutic hypothermia following cardiac arrest in the 2002. One is the multicenter randomized clinical trial projected by The Hypothermia after Cardiac Arrest Study Group. The other one was performed by four centers in Australia. Two trials significantly showed ...
7,138
The potential mechanisms of reduced incidence of ventricular fibrillation as the presenting rhythm in sudden cardiac arrest.
In the last two decades, the incidence of ventricular fibrillation has significantly decreased as the presenting rhythm in sudden cardiac arrest. We hypothesized that beta-adrenergic receptor blocker (beta-blocker) and angiotensin converting enzyme inhibitor, which were commonly used in the primary and secondary preven...
7,139
Alternative technique for implanting an implantable cardioverter defibrillator in infants.
We applied a new implanting technique for an implantable cardioverter defibrillator (ICD) in a 4-month-old girl with repeated ventricular fibrillation (Vf) due to long QT syndrome. This technique consisted of placement of an oval patch lead on the outer surface of the pericardium in the left pleural cavity. This was us...
7,140
Video-assisted thoracoscopic cardiac denervation: a potential novel therapeutic option for children with intractable ventricular arrhythmias.
Left cardiac sympathetic denervation is one of the therapeutic modalities used in the management of patients with medically refractory long QT syndrome. Traditionally, a thoracotomy or cervical incision has been used as the standard surgical approach for performing left cardiac sympathetic denervation. Video-assisted t...
7,141
Intermediate to long-term results of radiofrequency modified Maze procedure as an adjunct to open-heart surgery.
Of patients scheduled for elective open heart surgery, a substantial number of patients have preoperative atrial fibrillation (AF). The cut-and-sew Maze procedure and variant Maze procedures abolish AF in 45% to 95% during short- to intermediate-term follow-up. Limited data are available about maintenance of sinus rhyt...
7,142
[The use of a morphohistochemical method for the diagnosis of heart contusion].
This morphohistochemical study was carried out using myocardial tissue samples obtained from subjects with heart contusion. The aim of the study was to elucidate the cause of ventricular fibrillation associated with alternative myocardial insufficiency. It is concluded that changes of Ca2+ ion content in the myocardial...
7,143
The effect of rapid blood pressure control on P-wave dispersion in hypertensive urgency.
A sharp increase in blood pressure, increase in atrial pressure and atrial strain, left ventricular diastolic dysfunction, and left ventricular hypertrophy (LVH) lead to heterogeneity and instability in atrial conduction. The resulting physiopathological situation may elevate maximum Pwave duration (P(max)) and P-wave ...
7,144
Recent advances in metabolic syndrome and cardiovascular disease.
Metabolic syndrome is defined as an association of central obesity and several other cardiometabolic risk factors. Dysfunctional visceral adipose tissue and inflammatory status appear to be involved in its genesis. New definitions have decreased the threshold for glycaemia and one has lowered the threshold for waist ci...
7,145
Echocardiographic speckle tracking radial strain imaging to assess ventricular dyssynchrony in a pacing model of resynchronization therapy.
Speckle tracking imaging is a promising new echocardiographic method to assess left ventricular (LV) mechanical dyssynchrony. Our aim was to assess a new speckle tracking regional strain algorithm by comparison with angle-corrected tissue Doppler (TD) in an animal model of left bundle branch block and cardiac resynchro...
7,146
Prevalence and potential mechanisms of sustained ventricular arrhythmias during dobutamine stress echocardiography: a literature review.
Sustained ventricular tachycardia during dobutamine stress echocardiography is a rare complication of dobutamine stress echocardiography. It may be related to reduced left ventricular function and prior myocardial infarction but cannot be used as a sensitive or specific sign for myocardial ischemia. The clinical signif...
7,147
Ventricular arrhythmogenesis: insights from murine models.
Ventricular arrhythmias are the key underlying cause of sudden cardiac death, a common cause of mortality and a significant public health burden. Insights into the electrophysiological basis of such phenomena have been obtained using a wide range of recording techniques and a diversity of experimental models. As in oth...
7,148
[The incidence and predictors of atrial fibrillation in hypertrophic cardiomyopathy].
To observe the incidence and predictors of atrial fibrillation in hypertrophic cardiomyopathy (HCM).</AbstractText>612 HCM patients were analyzed prospectively from July 1990 to November 2007. The age, sex, height, weight, medical history, main symptoms and incidence of atrial fibrillation were recorded.</AbstractText>...
7,149
The A That Did Not Fib:Two Roads Both Traveled By.
<b>Case:</b> A 64-year-old woman presented with palpitations. Her 24-hour Holter monitor revealed runs of presumed atrial fibrillation (AF). The patient was referred for EP study and AF ablation. <b>EPS:</b> At EPS, an anterograde A-H jump was noted. Spontaneous bursts of tachycardia were seen, consisting of sinus atri...
7,150
Pharmacotherapy for atrial fibrillation in elderly hospitalized patients with comorbid congestive heart failure in australia: A retrospective study.
Despite the proven effectiveness of antiplatelet and anticoagulation treatment for atrial fibrillation (AF), their use has been suboptimal in practice, particularly in rural areas of Australia.</AbstractText>The aim of this study was to describe medication use in the management of AF in elderly hospitalized patients wi...
7,151
Innovation focus: the patient with arrhythmia.
Great strides have been made over the last two decades in the management of patients with rhythm disorders. Despite this, however, the remaining critical problems of stroke related to atrial fibrillation or as a result of radiofrequency ablation require innovative solutions to fully realize the potential of these recen...
7,152
Twisting until it breaks: a rare cause of ICD lead failure.
We describe a rare case of Twiddler's syndrome that resulted in a complex ICD lead fracture involving both the insulation and the conductor. The conductor fracture resulted in noise artefact that was interpreted by the device as ventricular fibrillation, but the patient had not received any shocks because the "episodes...
7,153
Natriuretic peptides in patients with atrial fibrillation.
The aim of the study was to evaluate plasma natriuretic peptides (NPs): atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) concentrations in patients with paroxysmal, persistent and permanent atrial fibrillation (AF).</AbstractText>The study groups consisted of 23 patients with paroxysmal AF, 42 patie...
7,154
Increased augmentation index of the radial pressure waveform in patients with paroxysmal atrial fibrillation.
The augmentation index, a marker of wave reflection, has been reported to reflect vascular properties and to determine left ventricular (LV) characteristics. We investigated the relationship between the augmentation index and paroxysmal atrial fibrillation (AF).</AbstractText>A total of 244 outpatients (122 patients wi...
7,155
Model systems for the discovery and development of antiarrhythmic drugs.
Cardiovascular diseases are the leading cause of mortality worldwide and about 25% of cardiovascular deaths are due to disturbances in cardiac rhythm or "arrhythmias". Arrhythmias were traditionally treated with antiarrhythmic drugs, but increasing awareness of the risks of presently available antiarrhythmic agents has...
7,156
Usefulness of rate regulation through continuous ventricular pacing in patients with drug-controlled slower atrial fibrillation and normal or depressed left ventricular systolic function.
We studied 33 clinically stable patients with permanent atrial fibrillation (AF), implanted with a ventricular demand rate-responsive (VVIR) pacemaker or an automatic defibrillator, in order to evaluate whether continuous right ventricular apex pacing (VP) conferring rate regulation may be advantageous when compared wi...
7,157
Ventricular arrhythmias originating from the epicardial ventricular outflow tract complicated with peripartum cardiomyopathy.
We report two cases undergoing electrophysiological studies for ventricular arrhythmias (VAs) associated with peripartum cardiomyopathy. Those two cases demonstrated that subsequent pregnancies might result in deterioration of VAs even though they exhibit no symptoms of heart failure. Those findings may clinically impa...
7,158
Effect of cardiac resynchronization therapy on conversion of persistent atrial fibrillation to sinus rhythm.
Spontaneous conversion of persistent atrial fibrillation to sinus rhythm (SR) has anecdotally been reported following cardiac resynchronisation therapy.</AbstractText>This monocenter observational study was designed to estimate the incidence of spontaneous conversion of persistent atrial fibrillation to SR in consecuti...
7,159
Ivabradine induces an increase in ventricular fibrillation threshold during acute myocardial ischemia: an experimental study.
Tachycardia often facilitates ischemic ventricular fibrillation (VF).</AbstractText>This study assessed the impact of ivabradine (IVA), a selective inhibitor of the cardiac pacemaker If current, on ventricular fibrillation threshold (VFT) during acute myocardial ischemia.</AbstractText>The experiments were conducted on...
7,160
Echocardiographic profile of peripartum cardiomyopathy in a tertiary care hospital in sokoto, Nigeria.
The diagnosis of peripartum cardiomyopathy in Nigeria has mostly been based on clinical criteria. Echocardiographic data are rare, even though echocardiography is useful in distinguishing this condition from others which mimic it. This is an effort to fulfill the need for such data.</AbstractText>A cross-sectional anal...
7,161
Cigarette smoking and risk of atrial fibrillation: the Rotterdam Study.
Cigarette smoking is an important risk factor for cardiovascular disease, but it is unknown whether it also contributes to the risk of atrial fibrillation.</AbstractText>The study is part of the Rotterdam Study, a population-based cohort study among subjects aged &gt; or =55 years. The association between cigarette smo...
7,162
Predominance of heart failure in the Heart of Soweto Study cohort: emerging challenges for urban African communities.
There is a paucity of data to describe the clinical characteristics of heart failure (HF) in urban African communities in epidemiological transition.</AbstractText>Chris Hani Baragwanath Hospital services the 1.1 million black African community of Soweto, South Africa. Of 1,960 cases of HF and related cardiomyopathies ...
7,163
Coronary vasospastic crisis leading to cardiogenic shock and recurrent ventricular fibrillation in a patient with long-standing asthma.
Acute myocardial infarction in patients with normal coronary arteries is a therapeutic dilemma. Coronary artery vasospasm and thrombosis are the most commonly encountered clinic problems and appear in localized coronary segments. The incidence of cardiovascular disease is increased in asthmatic patients. &#xdf;(2)-Adre...
7,164
Stroke prevention in atrial fibrillation and other major cardiac sources of embolism.
The frequency of cardioembolic stroke is expected to rise as the general population ages. Much of the increase may be attributed to atrial fibrillation, the most common cause of cardioembolic stroke and one that plays a substantial role in aging adults. Other sources of cardioembolic stroke may include ventricular thro...
7,165
Risks and challenges of implantable cardioverter-defibrillators in young adults.
The clinical use of the implantable cardioverter-defibrillator (ICD) is well established to prevent sudden death in patients with left ventricular dysfunction due to coronary artery disease and dilated cardiomyopathy, and its use has saved thousands of lives. More recently, its use has been extended to other patients a...
7,166
Recurrent ventricular arrhythmia storms in the age of implantable cardioverter defibrillator therapy: a comprehensive review.
Rapidly recurrent ventricular arrhythmia is not an infrequent clinical entity in the era of implantable cardioverter defibrillator therapy. Clinical presentation can vary dramatically, from multiple defibrillator shocks with hemodynamic instability, to asymptomatic delivery of anti-tachycardia pacing. Although some inv...
7,167
Ventricular fibrillation following autologous intramyocardial cell therapy for inherited cardiomyopathy.
A 41-year-old male with cardiomyopathy from an inherited beta myosin heavy-chain mutation underwent treatment for heart failure with intramyocardial cell transplantation. He received direct injections into his heart of autologous precursor cells isolated from his blood. He immediately suffered ventricular fibrillation....
7,168
Dynamic changes of left ventricular performance and left atrial volume induced by the mueller maneuver in healthy young adults and implications for obstructive sleep apnea, atrial fibrillation, and heart failure.
Using the Mueller maneuver (MM) to simulate obstructive sleep apnea (OSA), our aim was to investigate acute changes in left-sided cardiac morphologic characteristics and function which might develop with apneas occurring during sleep. Strong evidence supports a relation between OSA and both atrial fibrillation and hear...
7,169
Safety of contrast administration for endocardial enhancement during stress echocardiography compared with noncontrast stress.
The aim was to evaluate the safety of stress echocardiography using contrast (CE) for endocardial enhancement compared with a noncontrast (NCE) cohort in a large nonselect population. The recent Food and Drug Administration warning cited lack of data for safety regarding the use of contrast in conjunction with stress e...
7,170
Relation of mortality to failure to prescribe beta blockers acutely in patients with sustained ventricular tachycardia and ventricular fibrillation following acute myocardial infarction (from the VALsartan In Acute myocardial iNfarcTion trial [VALIANT] Registry).
Sustained ventricular arrhythmias and heart failure are well-recognized complications after acute myocardial infarction (AMI) and have been associated with worse outcomes and increased mortality. The use of and outcomes associated with acute beta-blocker therapy in patients with AMI complicated by sustained ventricular...
7,171
Treatment of patients with heart failure and preserved ejection fraction.
Of the more than 5 million Americans who have heart failure (HF), 30% to 50% have HF with preserved ejection fraction (HF-PEF). HF-PEF commonly occurs in elderly patients, especially women, with comorbidities of hypertension, left ventricular hypertrophy, diabetes, myocardial ischemia, and obesity. HF-PEF is associated...
7,172
Pharmacokinetics of ibutilide in patients with heart failure due to left ventricular systolic dysfunction.
To assess whether the increased risk of ibutilide-induced torsade de pointes in patients with heart failure may be due to increased ibutilide exposure, we sought to determine if the pharmacokinetics of ibutilide are altered in patients with heart failure due to left ventricular systolic dysfunction.</AbstractText>Multi...
7,173
[Effects of sympathetic nerve stimulation on connexin43 and ventricular arrhythmias during acute myocardial ischemia: experiment with rats].
To investigate the effects of sympathetic nerve stimulation (SNS) on connexin43 (Cx43) and ventricular arrhythmias during acute myocardial ischemia (MI).</AbstractText>Ninety five Wistar rats were randomly divided into four groups: MI group (n=25), undergoing: ligation of the anterior descending coronary; MII-SNS group...
7,174
A new completely flexible ring for mitral valve annuloplasty: the "Rama-Valvuloplasty-Ring". Five-year Piti&#xe9; Salp&#xe9;tri&#xe8;re experience.
The aim of this study was to analyze the effects about the use of a new completely flexible ring for mitral valve anuloplasty, the "Rama-Valvuloplasty-ring", in 182 patients operated on in the Piti&#xe9;-Salp&#xe9;tri&#xe8;re Hospital, Paris, France for mitral valve regurgitation (MVR). From January 1998 to December 20...
7,175
Transplantation of bone marrow mononuclear cells does not affect postinfarction electrical remodeling of the heart.
We studied the effect of allotransplantation of bone marrow mononuclear cells on postinfarction remodeling of the heart in rats. The cells were transplanted into the periinfarction zone of the heart. The transplantation was performed on day 9 after coronary occlusion. It was found that on day 45 after coronary occlusio...
7,176
Maternal cardiac arrest in early pregnancy.
A primigravid woman suffered a prolonged cardiac arrest at 18 weeks of gestation. Dilated ischemic cardiomyopathy was diagnosed. After recovery, the patient received an implantable cardioverter-defibrillator. At 38 weeks of gestation she had an elective caesarean delivery. Both mother and child had a favourable outcome...
7,177
Precordial steering wheel: a fortunate accident.
Myocardial ischemia has been associated with motor vehicle collisions (MVCs). However, we were unable to find reported cases of ST-segment elevation myocardial infarction (STEMI) leading to ventricular tachyarrhythmia and subsequent MVC. In such patients, decisions regarding antiplatelet and antithrombotic therapy need...
7,178
Action potential dynamics explain arrhythmic vulnerability in human heart failure: a clinical and modeling study implicating abnormal calcium handling.
The purpose of this study was to determine whether abnormalities of calcium cycling explain ventricular action potential (AP) oscillations and cause electrocardiogram T-wave alternans (TWA).</AbstractText>Mechanisms explaining why heart failure patients are at risk for malignant ventricular arrhythmias (ventricular tac...
7,179
[Treatment of atrial fibrillation in every days practice].
Atrial fibrillation is the most common arrhythmia in the adult. During recent years the therapeutic strategy has markedly changed. Some of these changes can be summarized as follows: Basis therapy includes betablockers and - in patients with structural heart disease - ACE-inhibitors and AT(1)-Blockers respectively. Cla...
7,180
Ventricular rate control using a novel vagus nerve stimulating system in a dog with chronic atrial fibrillation.
A 4-year-old, intact male Dogue de Bordeaux dog with congenital valvular pulmonic stenosis, tricuspid valve dysplasia, and chronic atrial fibrillation underwent ultrasound-guided balloon valvuloplasty in addition to pharmacological treatment. Owner compliance to prescribed pharmacotherapy proved very poor, and concerns...
7,181
Antiarrhythmic effect of reverse ventricular remodeling induced by cardiac resynchronization therapy: the InSync ICD (Implantable Cardioverter-Defibrillator) Italian Registry.
We investigated whether the reverse remodeling after cardiac resynchronization therapy (CRT) might reduce the occurrence of ventricular arrhythmias (VAs).</AbstractText>It is currently debated whether CRT has an effect on the burden of VAs.</AbstractText>The study included 398 patients treated with a CRT defibrillator ...
7,182
Atrial Arrhythmias in long-QT syndrome under daily life conditions: a nested case control study.
The long-QT syndromes (LQTS) are inherited electrical cardiomyopathies characterized by prolonged ventricular repolarization and ventricular arrhythmias. Several genetic reports have associated defects in LQTS-causing genes with atrial fibrillation (AF). We therefore studied whether atrial arrhythmias occur in patients...
7,183
[Underestimation of renal risk in cardiology clinics. RICAR study].
The aim of this study was to assess the rate of patients attended in cardiology outpatient clinics in whom microalbumine or glomerular filtration rate had been determined, at least once, in the previous 12 months.</AbstractText>It was an observational, transversal, multicentric study. 1224 patients were included from 1...
7,184
[Basic and advanced resuscitation of children].
The ERC Guidelines 2005 regarding the resuscitation of children and neonates recommend changes in treatment algorithms. Cardiac arrest in children is most often caused or worsened by hypoxic conditions. On confirmation of cardiac arrest in a child, treatment is initiated with 5 ventilations and continued with alternati...
7,185
Acute left atrial thrombosis during anticoagulant therapy in a patient with antithrombin deficiency.
A 47-year-old woman presented to our clinic 1 day after an intervention for a tibial shaft fracture because of sudden onset of chest pain and palpitations. Hospital drug therapy included enoxaparin. The ECG showed atrial fibrillation with a rapid ventricular rate. Transthoracic echocardiography showed a mass in the LA....
7,186
Idiopathic spontaneous coronary artery dissection: a case report.
Spontaneous coronary artery dissection frequently causes death, and most cases are diagnosed at autopsy. In most cases the affected persons are young pregnant females or women in the early postpartum period. We report a case of a female aged 36. She complained of acute chest pain and had ventricular fibrillation. She r...
7,187
Congestive heart failure with and without atrial fibrillation - different patient populations?
Heart failure (HF) and atrial fibrillation (AF) are common comorbid conditions in hospitalised patients. AF may occur when left ventricular (LV) systolic function deteriorates. The aim was to compare HF patients with AF to patients in sinus rhythm (SR).</AbstractText>Echocardiography and a cardiopulmonary exercise test...
7,188
Arrhythmias in patients with chronic obstructive pulmonary disease (COPD): occurrence frequency and the effect of treatment with the inhaled long-acting beta2-agonists arformoterol and salmeterol.
Beta-adrenergic stimulation may increase heart rate and the potential for cardiac arrhythmias. The effect of inhaled long-acting beta2-agonists (LABAs) on these outcomes was evaluated in patients with chronic obstructive pulmonary disease (COPD) in 2 double-blind randomized clinical trials. The pretreatment arrhythmia ...
7,189
Pre-ablative predictors of atrial fibrillation recurrence following pulmonary vein isolation: the potential role of inflammation.
An increasing body of evidence has demonstrated the essential role of inflammation in the genesis and maintenance of atrial fibrillation (AF). The aim of the present study was to investigate whether success or failure of electrical pulmonary vein isolation (PVI) in patients with AF is related with the presence of a pre...
7,190
d,l-Sotalol at therapeutic concentrations facilitates the occurrence of long-lasting non-stationary reentry during ventricular fibrillation in isolated rabbit hearts.
The effects of d,l-sotalol at therapeutic concentrations (&lt;or=10 mg/L) on wavefront dynamics during ventricular fibrillation (VF) and electrophysiological heterogeneity remain unclear.</AbstractText>By using an optical mapping system, epicardial activation patterns of VF were studied in 6 Langendorff-perfused rabbit...
7,191
Gender differences in clinical manifestations of Brugada syndrome.
We sought to assess differences in phenotype and prognosis between men and women in a large population of patients with Brugada syndrome.</AbstractText>A male predominance has been reported in the Brugada syndrome. No specific data are available, however, concerning gender differences in the clinical manifestations and...
7,192
[Ventricular fibrillation in acute myocardial infarction - do genes play a role?].
We present two patients with ventricular fibrillation (VF) during acute myocardial infarction (AMI). First patient had torsade de pointes ventricular tachycardia episodes degenerating into VF 10 days after AMI treated with primary angioplasty. Second patient had multiple episodes of VF during the first day of AMI. He s...
7,193
High-normal thyroid function and risk of atrial fibrillation: the Rotterdam study.
Overt and subclinical hyperthyroidism are both well-known independent risk factors for atrial fibrillation. We aimed to investigate the association of high-normal thyroid function with the development of atrial fibrillation in a prospective population-based study in the elderly.</AbstractText>The association between th...
7,194
Serum intact parathyroid hormone levels predict hospitalisation for heart failure.
To assess whether circulating levels of intact parathyroid hormone (intact PTH) in outpatients predict hospitalisation for heart failure (HF).</AbstractText>Eighty-eight consecutive outpatients with HF were enrolled in the study. The independent association between intact PTH and hospitalisation for HF was assessed usi...
7,195
Atrial and ventricular electrical and contractile remodeling and reverse remodeling owing to short-term pacing-induced atrial fibrillation in horses.
In humans, atrial fibrillation (AF) induces electrical, contractile, and structural remodeling leading to AF stabilization. Little is known about AF-induced atrial remodeling in horses.</AbstractText>Induced AF produces rapid atrial electrical and contractile remodeling in horses.</AbstractText>Six horses, 5 animals co...
7,196
Control of scroll-wave turbulence using resonant perturbations.
Turbulence of scroll waves is a sort of spatiotemporal chaos that exists in three-dimensional excitable media. Cardiac tissue and the Belousov-Zhabotinsky reaction are examples of such media. In cardiac tissue, chaotic behavior is believed to underlie fibrillation which, without intervention, precedes cardiac death. In...
7,197
Alternative presentation of tako-tsubo syndrome with spontaneous echo-contrast and "onion" shaped apical ballooning.
We report the case of a 79-year-old woman with transient left ventricular systolic dysfunction with apical ballooning (tako-tsubo like syndrome, TTS) showing an alternative newly reported "onion" shape. The patient was also characterized by atrial fibrillation and marked spontaneous echo-contrast: possible precipitatin...
7,198
Apparent seizure and atrial fibrillation associated with paliperidone.
A case of apparent seizure and atrial fibrillation associated with paliperidone is reported.</AbstractText>A 46-year-old man arrived at the emergency room (ER) via ambulance. Earlier that morning, his wife observed him awakening in a panic, drifting back to sleep, and then subsequently awakening in a panic with an appa...
7,199
Digoxin and clinical outcomes in systolic heart failure patients on contemporary background heart failure therapy.
Previous trials have shown that digoxin was beneficial in patients with heart failure (HF). However, these studies were conducted before the incorporation of beta blockers as standard therapy for patients with HF. The purpose of this study was to determine the effect of digoxin in patients with HF on a contemporary reg...