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7,200 | Echocardiographic and clinical risk factors for atrial fibrillation in hypertensive patients with ischemic stroke. | Atrial fibrillation (AF) is a common cause of ischemic stroke. Because anticoagulation can prevent many of these strokes, identifying patients with occult intermittent AF is important. Hypertension is a common precursor of stroke and AF. Prolonged nonselective electrocardiographic monitoring of patients after ischemic ... |
7,201 | Analysis of prehospital care for cardiac arrest in an urban setting in Japan. | In Japan, the management of prehospital care for cardiopulmonary arrest (CPA) has recently changed.</AbstractText>The characteristics of prehospital care for CPA were analyzed to identify predictors of prehospital return of spontaneous circulation (PROSC) and good recovery.</AbstractText>The characteristics of prehospi... |
7,202 | Reduced hands-off-time and time to first shock in CPR according to the ERC Guidelines 2005. | Chest compressions and early defibrillation are crucial in cardiopulmonary resuscitation (CPR). The Guidelines 2005 brought major changes to the basic life support and automated external defibrillator (BLS-AED) algorithm. We compared the European Resuscitation Council's Guidelines 2000 (group '00) and 2005 (group '05) ... |
7,203 | T-wave alternans found in preventricular tachyarrhythmias in CCU patients using a wavelet transform-based methodology. | Ventricular tachyarrhythmias are potentially lethal cardiac pathologies and the commonest cause of sudden cardiac death. Efforts to predict the onset of such events are based on feature extraction from the surface ECG. T-wave alternans (TWAs) are considered a marker of abnormal ventricular function that may be associat... |
7,204 | Phase-rectified signal averaging used to estimate the dominant frequencies in ECG signals during atrial fibrillation. | Phase-rectified signal averaging (PRSA) is a technique recently introduced to enhance quasi-periodic signal components. An important parameter that can be extracted from surface ECG is the dominant frequency (DF) of atrial fibrillation (AF). AF signal components are always highly contaminated by the ventricular complex... |
7,205 | The whole nine yards: multiple cardiac surgical and percutaneous interventions in a patient during 30 years of care. | A 38-year-old man underwent coronary artery bypass graft surgery for angina pectoris following myocardial infarction. During the following 28 years, he required two repeat coronary artery bypass graft surgical procedures, nine percutaneous coronary interventions and 17 coronary angiograms. His treatment included saphen... |
7,206 | Distinct lethal arrhythmias susceptibility is associated with sex-related difference in myocardial connexin-43 expression. | To elucidate gender-related differences in occurrence of sudden cardiac death the myocardial connexin-43 (Cx43) and the susceptibility of male and female rat hearts to ventricular fibrillation (VF) were investigated.</AbstractText>Ventricular tissues taken from male and female normotensive Wistar and spontaneously hype... |
7,207 | Acute beta-adrenoceptor blockade improves efficacy of ibutilide in conversion of atrial fibrillation with a rapid ventricular rate. | Activation of beta-adrenoceptors attenuates prolongation of action potential duration induced by blockade of the delayed rectifier potassium current. We examined whether acute administration of beta-blocker could enhance ibutilide (IB) efficacy in conversion of atrial fibrillation (AF) with a rapid ventricular rate.</A... |
7,208 | Defibrillation or cardiopulmonary resuscitation first for patients with out-of-hospital cardiac arrests found by paramedics to be in ventricular fibrillation? A randomised control trial. | To determine whether in patients with an ambulance response time of >5min who were in VF cardiac arrest, 3min of CPR before the first defibrillation was more effective than immediate defibrillation in improving survival to hospital discharge.</AbstractText>This randomised control trial was run by the South Australia... |
7,209 | Echo determinants of dyssynchrony (atrioventricular and inter- and intraventricular) and predictors of response to cardiac resynchronization therapy. | Cardiac resynchronization therapy (CRT) has revolutionized not only the treatment of chronic heart failure but also how we assess left ventricular (LV) dysfunction on echo. Increasingly, it has become clear that identifying and quantifying delays in events during the cardiac cycle is an important assessment in LV dysfu... |
7,210 | Intracardiac echocardiography in electrophysiology: a review of current applications in practice. | Intracardiac echocardiography (ICE) has emerged as a widespread useful tool in the everyday practice of interventional electrophysiology. Advances in catheter-based ultrasound transducers and imaging technology have made this modality integral to guiding evaluation of anatomy and ablation therapy. Evolution of ablative... |
7,211 | Mitral regurgitation and cardiac resynchronization therapy. | Secondary mitral regurgitation (MR) is frequent in patients with severely depressed left ventricular function. It increases mortality, and decreases exercise capacity. Its main mechanisms are multifactorial, related to apical and outward displacement of the papillary muscles, secondary to an enlarged and a more spheric... |
7,212 | Transmural recording of shock potential gradient fields, early postshock activations, and refibrillation episodes associated with external defibrillation of long-duration ventricular fibrillation in swine. | Knowledge of the shock potential gradient (nablaV) and postshock activation is limited to internal defibrillation of short-duration ventricular fibrillation (SDVF).</AbstractText>The purpose of this study was to determine these variables after external defibrillation of long-duration VF (LDVF).</AbstractText>In six pig... |
7,213 | Electrophysiological mechanisms of antiarrhythmic protection during hypothermia in winter hibernating versus nonhibernating mammals. | Robust cell-to-cell coupling is critically important in the safety of cardiac conduction and protection against ventricular fibrillation (VF). Hibernating mammals have evolved naturally protective mechanisms against VF induced by hypothermia and reperfusion injury.</AbstractText>We hypothesized that this protection str... |
7,214 | Sodium channel blocker tests allow a clear distinction of electrophysiological characteristics and prognosis in patients with a type 2 or 3 Brugada electrocardiogram pattern. | Patients with a type 2 or 3 Brugada syndrome (BS) pattern and a negative sodium channel blocker challenge (SCBC) are not considered as affected. Their arrhythmic prognosis is generally considered good, but it has never been specifically evaluated.</AbstractText>The purpose of this study was to evaluate the arrhythmic p... |
7,215 | Seasonal and circadian distributions of ventricular fibrillation in patients with Brugada syndrome. | It is well-known that the incidence of ventricular tachyarrhythmias is the highest in winter and during the daytime in patients with structural heart disease. However, little is known about the seasonal and circadian distributions of ventricular fibrillation (VF) in patients with Brugada syndrome.</AbstractText>The aim... |
7,216 | Obesity and dysrhythmias. | In the United States, obesity has reached epidemic proportions. Results from the 2003-2004 National Health and Nutrition Examination Survey estimated that 66% of US adults are either overweight (body mass index [BMI] 25-30 kg/m(2)) or obese (BMI>30 kg/m(2)) as defined by the BMI cutoffs established by the World Heal... |
7,217 | Downloadable algorithm to reduce inappropriate shocks caused by fractures of implantable cardioverter-defibrillator leads. | The primary method for monitoring implantable cardioverter-defibrillator lead integrity is periodic measurement of impedance. Sprint Fidelis leads are prone to pace-sense lead fractures, which commonly present as inappropriate shocks caused by oversensing.</AbstractText>We developed and tested an algorithm to enhance e... |
7,218 | Defibrillation threshold testing: is it necessary during implantable cardioverter-defibrillator implantation? | Defibrillation threshold (DFT) testing has traditionally been a routine part of implantable cardioverter-defibrillator (ICD) implantation. DFT testing was developed in the early days of the ICD when failure of defibrillation was common, recipients had a high-risk of ventricular tachycardia (VT) or ventricular fibrillat... |
7,219 | Approaching regional left atrial function by tissue Doppler velocity and strain imaging. | Atrial function is an integral part for the proper performance of the circulatory system. Assessment of its haemodynamic and mechanical characteristics by use of non-invasive echocardiography, including tissue Doppler velocity and strain imaging, may provide a better insight into atrial function and its relationship wi... |
7,220 | Electro-anatomic mapping systems in arrhythmias. | Electroanatomic mapping systems have permitted and facilitated difficult interventional ablation procedures for more than a decade. Initially, their use has been in arrhythmias in which the ablation target is difficult to identify, such as ventricular tachycardias in structural heart disease, atypical atrial flutters, ... |
7,221 | [Bouts of chest pain]. | We report on a 46-year-old man with vasospastic angina. The differential diagnosis, the eventful course of the patient and in particular the clinical image with diagnostic approach, therapy and prognosis of vasospastic angina are discussed. |
7,222 | Recurrent ventricular fibrillation caused by coronary artery spasm leading to implantable cardioverter defibrillator implantation. | Coronary artery spasm has been known to induce ischaemia and ventricular arrhythmias. We present a case of recurrent ventricular fibrillation caused by spasm-associated transmural myocardial ischaemia. During an intra-coronary acetylcholine provocation test, severe coronary spasm could be induced. The patient was treat... |
7,223 | Pediatric cardiopulmonary resuscitation: advances in science, techniques, and outcomes. | More than 25% of children survive to hospital discharge after in-hospital cardiac arrests, and 5% to 10% survive after out-of-hospital cardiac arrests. This review of pediatric cardiopulmonary resuscitation addresses the epidemiology of pediatric cardiac arrests, mechanisms of coronary blood flow during cardiopulmonary... |
7,224 | Late reoperations for Fontan patients: state of the art invited review. | Conversion of the atriopulmonary Fontan to a total cavopulmonary extracardiac connection with concomitant arrhythmia surgery and pacemaker placement is a safe and efficacious procedure for this patient population. From 1994 to 2007 a total of 118 patients have undergone this procedure with one (0.8%) early and nine (7.... |
7,225 | Intravenous infusion of bone marrow mesenchymal stem cells improves brain function after resuscitation from cardiac arrest. | Allogeneic bone marrow mesenchymal stem cells were previously shown to improve myocardial function when administered intravenously after resuscitation from cardiac arrest in rats. Coincidental evidence of improved brain function prompted the present study.</AbstractText>Prospective, randomized, controlled study.</Abstr... |
7,226 | Transthoracic application of electrical cardiopulmonary resuscitation for treatment of cardiac arrest. | Observational studies have shown that muscular stimulation contracting the thoracic cage may produce coronary perfusion pressures equal to manual chest compressions. This study examined electrical cardiopulmonary resuscitation for coronary perfusion pressures during ventricular fibrillation in a porcine model of cardia... |
7,227 | Targeting mitochondria for resuscitation from cardiac arrest. | Reversal of cardiac arrest requires reestablishment of aerobic metabolism by reperfusion with oxygenated blood of tissues that have been ischemic for variable periods of time. However, reperfusion concomitantly activates a myriad of pathogenic mechanisms causing what is known as reperfusion injury. At the center of rep... |
7,228 | Intra-arrest rapid head cooling improves postresuscitation myocardial function in comparison with delayed postresuscitation surface cooling. | To compare resuscitation outcomes and myocardial function among intra-arrest head cooling, delayed surface cooling, and uncooled controls.</AbstractText>Prospective animal study.</AbstractText>University-affiliated animal research laboratory.</AbstractText>Twenty-four male domestic pigs.</AbstractText>Ventricular fibri... |
7,229 | A comparison between head cooling begun during cardiopulmonary resuscitation and surface cooling after resuscitation in a pig model of cardiac arrest. | Employing transnasal head-cooling in a pig model of prolonged ventricular fibrillation, we compared the effects of 4 hrs of head-cooling started during cardiopulmonary resuscitation with those of 8 hrs of surface-cooling started at 2 hrs after resuscitation on 96-hr survival and neurologic outcomes.</AbstractText>Prosp... |
7,230 | Myocardial microcirculatory dysfunction after prolonged ventricular fibrillation and resuscitation. | The etiology of postresuscitation myocardial stunning is unknown but is thought to be related to either ischemia occurring during cardiac arrest and resuscitation efforts and/or reperfusion injury after restoration of circulation. A potential common pathway for postischemia/reperfusion end-organ dysfunction is microvas... |
7,231 | The amplitude spectrum area correctly predicts improved resuscitation and facilitated defibrillation with head cooling. | When systemic hypothermia was maintained before inducing cardiac arrest, the likelihood of successful defibrillation and meaningful survival was increased. When hypothermia is induced during cardiopulmonary resuscitation, mortality is also improved. With the introduction of the amplitude spectrum area as a predictor of... |
7,232 | From laboratory science to six emergency medical services systems: New understanding of the physiology of cardiopulmonary resuscitation increases survival rates after cardiac arrest. | The purpose of this study is to: 1) describe a newly mechanism of blood flow to the brain during cardiopulmonary resuscitation using the impedance threshold device in a piglet model of cardiac arrest, and 2) describe the survival benefits in humans of applying all of the highly recommended changes in the 2005 guideline... |
7,233 | Determinants of plasma NT-pro-BNP levels in patients with atrial fibrillation and preserved left ventricular ejection fraction. | The present study aimed to investigate the clinical and echocardiographic determinants of plasma NT-pro-BNP levels in patients with atrial fibrillation (AF) and preserved left ventricular ejection fraction (LVEF).</AbstractText>NT-pro-BNP levels were measured in 45 patients with paroxysmal AF, 41 patients with permanen... |
7,234 | Cardiac arrhythmia during propofol sedation. | Recent articles have described the increasing frequency of use of propofol as a sedating agent in the ED, and praise the safety profile of propofol when used in this manner. We describe a patient who developed torsade de pointes followed by ventricular fibrillation while undergoing propofol sedation for closed reductio... |
7,235 | T-wave alternans: reviewing the clinical performance, understanding limitations, characterizing methodologies. | Accurate recognition of individuals at higher immediate risk of sudden cardiac death (SCD) is still an open question. The fortuitous nature of acute cardiovascular events just does not seem to fit the well-known model of ventricular tachycardia/fibrillation induction in a static arrhythmogenic substrate by a synchronou... |
7,236 | [Short time ECG signal analysis based on the reconstruction of phase space]. | Based on the reconstruction of two-dimension phase space of time series of short ECG signals, the variation of the strange attractor geometry is described and two indices, VMI and VAI, are derived in this paper. The two indices can distinguish clearly the ECG signals of sinus rhythm, tachycardia and ventricular fibrill... |
7,237 | Acute coronary syndromes in patients with prosthetic heart valves-a case-series. | There are few reports regarding acute coronary syndromes (ACS) in patients with prosthetic heart valves (PHV), mostly attributing the ACS to a PHV-derived coronary embolus.</AbstractText>To characterize a case-series of ACS patients with PHV.</AbstractText>All patients in our institution with previous PHV surgery and A... |
7,238 | Safety of the novel atrial-selective K+-channel blocker AVE0118 in experimental heart failure. | Congestive heart failure (CHF) is often associated with atrial fibrillation. The safety of many antiarrhythmic drugs in CHF is limited by proarrhythmic effects. We aimed to assess the safety of a novel atrial-selective K(+)-channel blocker AVE0118 in CHF compared to a selective (dofetilide) and a non-selective IKr bloc... |
7,239 | Recurrent perimesencephalic subarachnoid hemorrhage during antithrombotic therapy. | In patients with non-aneurysmal perimesencephalic hemorrhage, spontaneous rebleeding does not occur. The lack of reported recurrences may lead to less cautious administration of antithrombotic therapy.</AbstractText>Case report.</AbstractText>A 57-year-old woman with a perimesencephalic pattern of hemorrhage and negati... |
7,240 | [Impact of electrical shock waveform and paddle positions on efficacy of direct current cardioversion for atrial fibrillation]. | Direct-current electrical cardioversion is the main method for the conversion of atrial fibrillation. Its success depends on many factors. In several studies, biphasic shock waveforms have been demonstrated to be superior to monophasic shocks for termination of atrial fibrillation; however, information about impact of ... |
7,241 | Defibrillation testing and early neurologic outcome. | During implantable cardioverter-defibrillator (ICD) implantation, ventricular defibrillation testing (DFT) is considered a standard procedure. This procedure often requires multiple ventricular fibrillation (VF) inductions. These repeated short episodes of circulatory arrest with global cerebral ischemia may cause neur... |
7,242 | Atrial pacing, the forgotten pacing mode. | In patients with sick sinus syndrome and normal atrioventricular conduction, physiological pacing can be accomplished with either a single chamber atrial pacemaker AAI/R or a dual chamber pacemaker DDD/R. The single chamber device has the advantages of simpler implantation and lower initial costs, while the dual chambe... |
7,243 | Atrial Fibrillation and Congestive Heart Failure: should we aim to control the heart's rate or its rhythm? | The Atrial Fibrillation and Congestive Heart Failure trial, which was conducted in patients with a reduced left ventricular ejection fraction, demonstrates that prognosis is independent of whether treatment is targeted towards controlling the heart's rate or its rhythm. The study also showed that other factors, such as... |
7,244 | The early minutes of in-hospital cardiac arrest: shock or CPR? A population based prospective study. | In the early minutes of cardiac arrest, timing of defibrillation and cardiopulmonary resuscitation during the basic life support phase (BLS CPR) is debated. Aims of this study were to provide in-hospital incidence and outcome data, and to investigate the relation between outcome and time from collapse to defibrillation... |
7,245 | Cardiac arrest with pulseless electrical activity associated with methylphenidate in an adolescent with a normal baseline echocardiogram. | Recent concerns of adverse cardiac events associated with drugs used to treat attention-deficit-hyperactivity disorder (ADHD) have prompted debate over whether these drugs are truly safe. We describe a 17-year-old boy with a normal baseline echocardiogram who had been taking methylphenidate for ADHD for 18 months and e... |
7,246 | Role of microvolt T-wave alternans in assessment of arrhythmia vulnerability among patients with heart failure and systolic dysfunction: primary results from the T-wave alternans sudden cardiac death in heart failure trial substudy. | Sudden cardiac death remains a leading cause of mortality despite advances in medical treatment for the prevention of ischemic heart disease and heart failure. Recent studies showed a benefit of implantable cardioverter defibrillator implantation, but appropriate shocks for ventricular tachyarrhythmias were noted only ... |
7,247 | High-throughput analysis of drug binding interactions for the human cardiac channel, Kv1.5. | The voltage-gated potassium channel Kv1.5 is one of the key regulators of membrane potential repolarization in human atrial myocytes and is considered a potential drug target to treat atrial fibrillation. In this study we sought to determine molecular mechanism of action of DPO-1, a diphenylphosphine oxide derivative r... |
7,248 | The central nervous system cytokine response to global ischemia following resuscitation from ventricular fibrillation in a porcine model. | Pro-inflammatory cytokines have been implicated as culprits in neurotoxicity following ischemia in small animal models of stroke. The aim of this study was to measure the central nervous system (CNS) cytokine response following resuscitation from ventricular fibrillation (VF) in a porcine model of cardiac arrest and gl... |
7,249 | Predictive power of serum NSE and OHCA score regarding 6-month neurologic outcome after out-of-hospital ventricular fibrillation and therapeutic hypothermia. | To determine the predictive power of the out-of-hospital cardiac arrest (OHCA) score and serum neuron-specific enolase (NSE) in patients resuscitated from ventricular fibrillation treated with therapeutic hypothermia (TH) and glucose control.</AbstractText>An analysis of prospectively collected data of 90 TH patients. ... |
7,250 | Improving countershock success prediction during cardiopulmonary resuscitation using ventricular fibrillation features from higher ECG frequency bands. | Countershock outcome prediction using ventricular fibrillation (VF) feature analysis needs undisturbed electrocardiogram (ECG) signals and therefore requires interruption of cardiopulmonary resuscitation (CPR). Features that originate from higher frequency bands of the VF power spectrum may be less affected by CPR arte... |
7,251 | Clinical outcome of patients with heart failure and preserved left ventricular function. | Patients with heart failure have a poor prognosis. However, it has been presumed that patients with heart failure and preserved left ventricular function (LVF) may have a more benign prognosis.</AbstractText>We evaluated the clinical outcome of patients with heart failure and preserved LVF compared with patients with r... |
7,252 | Ibutilide therapy for atrial fibrillation: 5-year experience in a community hospital. | Many institutions restrict the use of ibutilide because of the potential risk of polymorphic ventricular tachycardia (PMVT). Over a 5-year period from June 2000 to May 2005, 238 patients, 151 men and 87 women, with a mean age of 67.1 years (range, 22-94 years), received intravenous ibutilide at our institution. Ibutili... |
7,253 | Relationship between New York Heart Association class change and ventricular tachyarrhythmia occurrence in patients treated with cardiac resynchronization plus defibrillator. | In patients with advanced heart failure (HF) and prolonged QRS interval, cardiac resynchronization therapy (CRT) reduces symptoms and risk of death. The added benefit of an implantable cardioverter defibrillator (ICD) remains questionable in some patients.</AbstractText>In 332 HF patients treated with CRT-D (CRT with I... |
7,254 | Analysis of atrial fibrillation: from electrocardiogram signal processing to clinical management. | The analysis of atrial fibrillation in non-invasive ECG recordings has received considerable attention in recent years, spurring the development of signal processing techniques for more advanced characterization of the atrial waveforms than previously available. The present paper gives an overview of different approach... |
7,255 | Rhythmic abdominal compression CPR ventilates without supplemental breaths and provides effective blood circulation. | Standard chest-compression CPR has an out-of-hospital resuscitation rate of less than 10% and can result in rib fractures or mouth-to-mouth transfer of infection. Recently, we introduced a new CPR method that utilizes only rhythmic abdominal compressions (OAC-CPR). The present study compares ventilation and hemodynamic... |
7,256 | Vigilance, awareness and a phone line: 20 years of expediting CPR for enhancing survival after out-of-hospital cardiac arrest. The 'SHL'-Telemedicine experience in Israel. | The only large-scale report (1988) by the Israeli national ambulance service Magen David Adom (MDA) on the outcome of cardiac arrest victims who underwent cardiopulmonary resuscitation (CPR) by paramedics called for more frequent and more promptly initiated CPR and shorter time to arrival of paramedic care to improve s... |
7,257 | Blood pressure and heart rate immediately after termination of short-term ventricular fibrillation. | Implantable cardioverter/defibrillators (ICDs) can detect ventricular fibrillation (VF) and terminate it. For determining the optimal defibrillation threshold, ventricular fibrillation is repetitively induced and terminated with DC shocks. Depending on the protocol, several fibrillation/defibrillation sequences are man... |
7,258 | Precordial thump efficacy in termination of induced ventricular arrhythmias. | Reports about the efficacy of precordial thump (PT) in the termination of ventricular arrhythmias (VA) vary widely. Very little recent data about the mechanical termination of VA induced during programmed ventricular stimulation are available.</AbstractText>We prospectively studied 485 consecutive patients (May 2001 to... |
7,259 | Effects of pre-arrest and intra-arrest hypothermia on ventricular fibrillation and resuscitation. | Hypothermia has been shown to improve survival and neurological outcomes for ventricular fibrillation (VF) cardiac arrest. The electrophysiological mechanisms of hypothermia are not well-understood, nor are the effects of beginning cooling during the resuscitation.</AbstractText>We hypothesized that inducing hypothermi... |
7,260 | Spontaneous gasping increases cerebral blood flow during untreated fatal hemorrhagic shock. | Gasping has been found to be associated with improved ventilation, stroke volume, and cerebral blood flow (CBF) during untreated ventricular fibrillation. However, its effects have not been thoroughly assessed during fatal hemorrhagic shock. In this study, we hypothesized that gasping increases CBF during fatal hemorrh... |
7,261 | Cardiac catheterization is underutilized after in-hospital cardiac arrest. | Indications for immediate cardiac catheterization in cardiac arrest survivors without ST elevation myocardial infarction (STEMI) are uncertain as electrocardiographic and clinical criteria may be challenging to interpret in this population. We sought to evaluate rates of early catheterization after in-hospital ventricu... |
7,262 | Effect of cooling after human cardiac arrest on myocardial infarct size. | The Hypothermia after Cardiac Arrest (HACA) trial assessed whether mild therapeutic hypothermia improved the rate of good neurological recovery in patients after ventricular fibrillation cardiac arrest of presumed cardiac origin. We evaluated the impact of hypothermia on myocardial injury.</AbstractText>Re-analysis of ... |
7,263 | Benchmarking ventricular arrhythmias in the mouse--revisiting the 'Lambeth Conventions' 20 years on. | The isolated Langendorff-mode perfused heart has become a valuable experimental model, used extensively to examine cardiac function, pathophysiology and pharmacology. For the clinical cardiologist an ECG is often a simple practicality, however in experimental circumstances, particularly with ex vivo murine hearts it is... |
7,264 | A randomized trial of the effect of automated ventricular capture on device longevity and threshold measurement in pacemaker patients. | An automatic capture (AC) algorithm adjusts ventricular pacing output to capture the ventricle while optimizing output to 0.5 V above threshold. AC maintains this output and confirms capture on a beat-to-beat basis in bipolar and unipolar pacing and sensing.</AbstractText>To assess the AC algorithm and its impact on de... |
7,265 | Nonischemic dilated cardiomyopathy: results of noninvasive and invasive evaluation in 310 patients and clinical significance of bundle branch block. | The survival of patients with idiopathic dilated cardiomyopathy (IDCM) at III and IV stages of New York Heart Association (NYHA) is decreased in those with a bundle branch block (BBB) compared to those without BBB. Less is known on the prognosis of patients at earlier stages of NYHA and who had a left BBB (LBBB) or rig... |
7,266 | Insulin sensitivity measured by the euglycaemic insulin clamp and proinsulin levels as predictors of stroke in elderly men. | <AbstractText Label="AIMS/HYPOTHESIS" NlmCategory="OBJECTIVE">Our aim was to investigate the predictive power of a panel of variables in glucose and insulin metabolism for the incidence of stroke or transient ischaemic attacks (TIA). We hypothesised that proinsulin and insulin resistance contributes to an increase of r... |
7,267 | Early results of off-pump coronary artery bypass graft surgery using bilateral internal thoracic artery grafts in octogenarian patients during ten years. | The aim of this study is to review the outcome of OP-CABG using bilateral internal thoracic artery (BITA) grafts in these patients in terms of morbidity and mortality.</AbstractText>Retrospective data from consecutive 64 octogenarian patients who underwent this surgery in the period between April 1998 and December 2007... |
7,268 | Diagnosis and treatment of pulmonary arterial hypertension and atrial fibrillation in an adult chimpanzee (Pan troglodytes). | This report describes the diagnosis and treatment of pulmonary arterial hypertension (PAH) in an adult male captive chimpanzee. Although cardiovascular disease in general is common in human and great apes, diagnosis and treatment of PAH in nonhuman primates are uncommon. In the case we present, the adult chimpanzee was... |
7,269 | The heme oxygenase inducer hemin protects against cardiac dysfunction and ventricular fibrillation in ischaemic/reperfused rat hearts: role of connexin 43. | Cardiac expression of cytoprotective gene heme oxygenase-1 (HO-1) is modulated by ischaemia and reperfusion (I/R). We therefore hypothesized that pretreatment with hemin, an inductor of HO-1, would precondition the heart against post-ischaemic dysfunction and ventricular fibrillation (VF). Male Wistar rats were given e... |
7,270 | Adaptive singular value cancelation of ventricular activity in single-lead atrial fibrillation electrocardiograms. | The proper analysis and characterization of atrial fibrillation (AF) from surface electrocardiographic (ECG) recordings requires to cancel out the ventricular activity (VA), which is composed of the QRS complex and the T wave. Historically, for single-lead ECGs, the averaged beat subtraction (ABS) has been the most wid... |
7,271 | Early repolarization phenomenon in arrhythmogenic right ventricular dysplasia-cardiomyopathy and sudden cardiac arrest due to ventricular fibrillation. | The case of a 26-year-old male with sudden cardiac arrest due to ventricular fibrillation and the final diagnosis of arrhythmogenic right ventricular dysplasia-cardiomyopathy (ARVD/C) and initial early repolarization phenomenon is presented in detail. An additional analysis of early repolarization in additional 359 pat... |
7,272 | [Acute heart failure and preserved systolic function: can we explain all only by the diastolic dysfunction? A prospective study on 145 patients hospitalized for acute pulmonary edema]. | Heart failure with conserved systolic function is frequent and attributed to the diastolic dysfunction. The diagnosis of diastolic heart failure requires the association of clinical signs of heart failure, a conserved left ventricular systolic function and a diastolic dysfunction.</AbstractText>To determine the proport... |
7,273 | Management of high defibrillation threshold. | The implantable cardioverter defibrillator (ICD) has become the primary therapy for the treatment of potentially lethal ventricular arrhythmias. Ventricular arrhythmias encompass a spectrum of rhythm disturbances ranging from the occasional monomorphic ventricular premature complex to the almost universally fatal ventr... |
7,274 | Hypoglycaemia as a possible cause of transient ischaemic attack in a patient with multiple vascular risk factors. | An elderly, fibrillating, diabetic hypertensive patient in heart failure is at risk of stroke from all her cardiovascular morbidities. When such a patient presents with stroke, it is usually difficult to squarely incriminate one. Consequently, precious time is lost while care givers conduct expensive investigations to ... |
7,275 | [Ventricular arrhythmias of catecholaminergic origin and sudden death]. | The hereditary disease known as polymorphic catecholaminergic ventricular tachycardia (PCVT) is highly lethal. Almost 30% of the affected patients die before 40 years old, mainly due to sudden cardiac death. We have used isolated hearts from mutant mice (type 2 ryanodine receptors, RyR2/RyR2(R4496C)) to investigate arr... |
7,276 | [Cardiothyrotoxicosis in the young adult in Marrakech. A report of 36 cases]. | Thyrotoxicosis is underdiagnosed because of its low occurrence in series from Africa. The aim of this study was to evaluate the frequency, the demographic data, and the etiological aspects of thyrotoxicosis among hyperthyroidy. Thirty-six patients with thyrotoxicosis (group I) gathered during a period of four years was... |
7,277 | Paroxysmal atrial fibrillation is associated with increased intra-atrial conduction delay. | A novel electrophysiological technique, paced electrogram fractionation analysis (PEFA), which measures activation delay of stimulated beats through the myocardium, has shown that long delays in activation are strongly associated with sudden cardiac death due to ventricular fibrillation. The aim of our study was to det... |
7,278 | Atrial fibrillation with rapid ventricular response in pregnancy. | To report a case of atrial fibrillation with rapid ventricular response occurring during pregnancy.</AbstractText>A 35-year-old woman, gravida 3, para 1, abortus 1, with a history of persistent supraventricular arrhythmia, presented at 22 weeks' gestation. After adenosine administration, electrocardiography revealed at... |
7,279 | Outcome of patients with haemodynamically stable ventricular tachycardia treated with an implantable cardioverter-defibrillator. | The benefit of implantable cardioverter defibrillator (ICD) therapy in patients with haemodynamically stable ventricular tachycardia (VT) is not well documented.</AbstractText>In this single-centre observational study, we examined the medical records of 53 patients (48 men, mean age 66 +/- 1 years) treated with an ICD.... |
7,280 | Heart rhythm and cardiac pacing: an integrated dual-chamber heart and pacer model. | Modern cardiac pacemaker can sense electrical activity in both atrium and ventricle, and deliver precisely timed stimulations to one or both chambers on demand. However, little is known about how the external cardiac pacing interacts with the heart's intrinsic activity. In this study, we present an integrated dual-cham... |
7,281 | Rhabdomyolysis after liver transplantation: a case report. | Our aim was to present the case of a pediatric biliary atresia patient who experienced rhabdomyolysis with severe cardiac arrhythmias associated with hyperkalemia, metabolic acidosis, and myoglobulinemia during liver transplantation. A 5-year-old girl, weighing 16.5 kg, with end-stage liver disease due to biliary atres... |
7,282 | U-waves and T-wave peak to T-wave end intervals in patients with catecholaminergic polymorphic ventricular tachycardia, effects of beta-blockers. | Catecholaminergic polymorphic ventricular tachycardia (CPVT) is characterized by risk of polymorphic ventricular tachycardia (pVT) and sudden death during stress. Experimental CPVT models show that delayed afterdepolarization (DAD)-induced triggered activity is the initiating mechanism of pVT, whereas an increase in tr... |
7,283 | Omega-3 fatty acid: a role in the management of cardiac arrhythmias? | The objective of this study was to review and evaluate published evidence on the use of omega-3 fatty acid in the prevention and treatment of atrial and ventricular arrhythmias. Postulated mechanisms of the antiarrhythmic effects of omega-3 fatty acid are discussed.</AbstractText>Peer-reviewed articles/abstracts publis... |
7,284 | New horizons in antiarrhythmic therapy: will novel agents overcome current deficits? | Pharmacologic antiarrhythmic therapy is the most commonly used treatment in most patients with atrial fibrillation (AF), but currently available agents are limited by risks that may offset the benefits of sinus rhythm. The development of antiarrhythmic agents with the potential for fewer adverse ventricular effects and... |
7,285 | Atrial fibrillation in Mediterranean spotted fever. | Mediterranean spotted fever (MSF) is a tick-borne acute febrile disease caused by Rickettsia conorii and characterized by fever, maculo-papular rash and a black eschar at the site of the tick bite ('tache noir'). We describe the case of a 58-year-old man affected by MSF who developed atrial fibrillation. The patient pr... |
7,286 | Patient with hypofibrinolysis-mediated thromboembolism converted to a hypercoagulable/hyperfibrinolytic state via ventricular assist device placement. | Mechanical circulatory support with ventricular assist devices (VADs) for end-stage heart failure has been a focus of intense interest for nearly four decades. Despite improvements in VAD design and biomaterial composition, it is common to administer anti-coagulation (e.g., warfarin, anti-platelet agents) to prevent bo... |
7,287 | Long-term outcome and risk stratification in dilated cardiolaminopathies. | The aim of this study was to analyze the long-term follow-up of dilated cardiolaminopathies.</AbstractText>Lamin A/C (LMNA) gene mutations cause a variety of phenotypes. In the cardiology setting, patients diagnosed with idiopathic dilated cardiomyopathy (DCM) plus atrioventricular block (AVB) constitute the majority o... |
7,288 | J-point elevation in survivors of primary ventricular fibrillation and matched control subjects: incidence and clinical significance. | The purpose of this study was to determine whether J-point elevation is a marker of arrhythmic risk.</AbstractText>J-point elevation has been considered an innocent finding among healthy young individuals (the "early repolarization" pattern). However, this electrocardiogram (ECG) finding is increasingly being associate... |
7,289 | Symptomatic ventricular tachyarrhythmia is associated with delayed gadolinium enhancement in cardiac magnetic resonance imaging and with elevated plasma brain natriuretic peptide level in hypertrophic cardiomyopathy. | Delayed gadolinium enhancement (DGE) in cardiac magnetic resonance (CMR) imaging indicates the areas with myocardial fibrosis, which are suggested to be arrhythmogenic substrate in hypertrophic cardiomyopathy (HCM). Elevated brain natriuretic peptide (BNP) is associated with cardiovascular events in HCM. We investigate... |
7,290 | Improvement in prognosis of dilated cardiomyopathy in the elderly over the past 20 years. | Although dilated cardiomyopathy (DCM) had a poor prognosis in the past, recent studies have shown better survival. However, little is known about the improvement of prognosis in the elderly. This study sought to clarify the changes in prognosis in elderly patients with DCM over the past 20 years.</AbstractText>We studi... |
7,291 | Association between serum C-reactive protein elevation and atrial fibrillation after first anterior myocardial infarction. | Elevated inflammatory markers have been found to correlate with higher risk for cardiac events in patients with acute myocardial infarction (AMI). It has been suggested that C-reactive protein (CRP) may be involved in the initiation process of atrial fibrillation (AF). However, the role of CRP levels in the occurence o... |
7,292 | Successful conversion of recent-onset atrial fibrillation by sequential administration of up to three antiarrhythmic drugs. | Short-term conversion attempt of recent-onset atrial fibrillation (AF) in the emergency room fails too often. Many patients and doctors still prefer pharmacological to electrical solutions in such cases.</AbstractText>Sequential administration of up to 3 antiarrhythmic drugs of different classes of action (amiodarone, ... |
7,293 | Catheter ablation of a polymorphic ventricular tachycardia inducing monofocal premature ventricular complex. | Ventricular tachycardia originating from the right ventricular outflow tract (RVOT) is considered benign, but sometimes it causes polymorphic ventricular tachycardia and ventricular fibrillation, resulting in sudden cardiac death. A 58-year-old woman without structural heart disease was admitted for evaluation of recur... |
7,294 | Acute myocarditis mimicking lateral myocardial infarction. | We report a case of myocarditis mimicking acute lateral myocardial infarction and treated as such initially, which was complicated by ventricular fibrillation a few hours after admission to the intensive care unit. The correct diagnosis was rapidly made using a low-dose delayed-enhanced cardiac multidetector computed t... |
7,295 | Resveratrol attenuates ventricular arrhythmias and improves the long-term survival in rats with myocardial infarction. | The effects of resveratrol treatment on ventricular arrhythmia, survival, and late cardiac remodeling were evaluated in rats with myocardial infarction (MI).</AbstractText>Three groups of rats (S: ham-operated, MI, and MI pre-treated with resveratrol) were treated in an in vivo MI model by ligation of left anterior des... |
7,296 | Reduction of right ventricular pacing in patients with sinus node dysfunction through programming a long atrioventricular delay along with the DDIR mode. | Right ventricular (RV) pacing increases the incidence of atrial fibrillation (AF) and hospitalization rate for heart failure. Many patients with sinus node dysfunction (SND) are implanted with a DDDR pacemaker to ensure the treatment of slowly conducted atrial fibrillation and atrioventricular (AV) block. Many pacemake... |
7,297 | Anticoagulant drugs in noncompaction: a mandatory therapy? | Noncompaction of left ventricular myocardium is a rare congenital cardiomyopathy resulting from an incomplete myocardial morphogenesis that leads to the persistence of the embryonic myocardium. This condition is characterized by a thin compacted epicardial and an extremely thickened endocardial layer with prominent tra... |
7,298 | Characterization of multiple spiral wave dynamics as a stochastic predator-prey system. | A perspective on systems containing many action potential waves that, individually, are prone to spiral wave breakup is proposed. The perspective is based on two quantities, "predator" and "prey," which we define as the fraction of the system in the excited state and in the excitable but unexcited state, respectively. ... |
7,299 | The effect of preoperative circadian blood pressure pattern on early postoperative outcomes in patients with coronary artery bypass graft surgery. | The aim of this prospective study was to evaluate the relationship between preoperative circadian blood pressure pattern and early postoperative course in patients undergoing coronary artery bypass graft (CABG) surgery.</AbstractText>One hundred and thirty patients planning to undergo isolated CABG operation were inclu... |
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