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7,000 | [Acute phase of Chagas disease in the Brazilian Amazon region: study of 233 cases from Pará, Amapá and Maranhão observed between 1988 and 2005]. | Two hundred and thirty-three cases of the acute phase of Chagas disease, from Pará, Amapá and Maranhão, were observed between 1988 and 2005. One hundred and sixty were studied retrospectively from 1988 to 2002 and seventy-three were prospectively followed up from 2003 to 2005. Among the cases studied, 78... |
7,001 | Reversible dilated cardiomyopathy associated with post-partum thyrotoxic storm. | The following case of a young mother presenting with post-partum pulmonary oedema, highlights a singular and life-threatening complication of a common condition (thyrotoxicosis). While thyrotoxic heart disease is well described, thyrotoxic storm in the post-partum period associated with dilated cardiomyopathy, congesti... |
7,002 | Isoelectric PVCs diagnosed with a monitor with simultaneous ECG, and ICD intracardiac electrogram and marker channels. | A 78-year-old woman with a remote history of chronic atrial fibrillation and catheter ablation of the atrioventricular node with a permanent ventricular pacemaker sustained a syncopal episode. Interrogation of her pacemaker revealed electrograms of ventricular fibrillation with a duration of 26 seconds. The patient und... |
7,003 | Drug therapy for atrial fibrillation: what will its role be in the era of increasing use of catheter ablation? | Atrial fibrillation (AF) is an increasingly important disorder. In most patients the treatment of AF usually employs anti-arrhythmic drugs (AADs). Despite the widespread utilization of AADs for the conversion of atrial fibrillation and maintenance of normal sinus rhythm, their use is limited by modest efficacy, frequen... |
7,004 | Ventricular proarrhythmic effects of atrial fibrillation are modulated by depolarization and repolarization anomalies in patients with left ventricular dysfunction. | Atrial fibrillation (AF) may have a ventricular proarrhythmic effect, particularly in the setting of heart failure. We assessed whether AF predicts appropriate implantable cardioverter-defibrillator (ICD) shocks in patients with left ventricular dysfunction and explored modulators of risk.</AbstractText>A retrospective... |
7,005 | Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation. | Small conductance Ca(2+)-activated K(+) channels (SK channels) have been reported in excitable cells, where they aid in integrating changes in intracellular Ca(2+) (Ca(2+)(i)) with membrane potential. We have recently reported the functional existence of SK2 channels in human and mouse cardiac myocytes. Moreover, we ha... |
7,006 | Management of atrial fibrillation--Part 2. | Many cardiologists prefer, especially in older patients, ventricular rate control plus warfarin rather than maintaining sinus rhythm with anti-arrhythmic drugs. Patients with chronic or paroxysmal AF at high risk for stroke should be treated with long-term warfarin to achieve an International Normalized Ratio of 2.0 to... |
7,007 | Catheter ablation - new developments in robotics. | Catheter ablation has become the curative treatment modality for various arrhythmias. Extending the indications for catheter ablation from simple supraventricular tachycardias to complex arrhythmias such as ventricular tachycardia or atrial fibrillation, the investigator faces prolonged procedure times, fluoroscopy exp... |
7,008 | New antiarrhythmic drugs for the treatment of atrial fibrillation. | Atrial fibrillation (AF) is the most common arrhythmia requiring medical care, with a prevalence of almost 1% in the adult population. Particularly in the expanding elderly population, pharmacological therapy is and will continue to be the mainstay of AF therapy. Many currently used antiarrhythmic drugs have limited ef... |
7,009 | Acute efficacy of low-dose human atrial natriuretic peptide monotherapy without loop diuretics for acute decompensated heart failure with left ventricular systolic dysfunction: a case report. | A 64-year-old man was admitted to our hospital with new-onset acute decompensated heart failure (ADHF). He had left ventricular systolic dysfunction and chronic atrial fibrillation with a rapid ventricular response. Initial treatment with low-dose recombinant human atrial natriuretic peptide (hANP) alone and no loop di... |
7,010 | Recurrent acute pulmonary embolism and paroxysmal atrial fibrillation associated with subclinical hyperthyroidism. | Subclinical hyperthyroidism is an increasingly recognized entity that is defined as a normal serum free thyroxine and free triiodothyronine levels with a thyroid-stimulating hormone level suppressed below the normal range and usually undetectable. It has been reported that subclinical hyperthyroidism is not associated ... |
7,011 | Cavopulmonary anastomosis improves left ventricular assist device support in acute biventricular failure. | Right ventricular failure during left ventricular assist device (LVAD) support can result in severe hemodynamic compromise with high mortality. This study investigated the acute effects of cavopulmonary anastomosis on right ventricular loading and LVAD performance in a model of severe biventricular failure.</AbstractTe... |
7,012 | A note on a method for determining advantageous properties of an anti-arrhythmic drug based on a mathematical model of cardiac cells. | Regional hyperkalemia during acute ischemia may provoke cardiac arrhythmias such as ventricular fibrillation. Despite intense research efforts over the last decades, the problem of finding an efficient anti-arrhythmic drug without dangerous side effects is still open. One approach to analyze the effect of anti-arrhythm... |
7,013 | Sudden cardiac death complicating alcohol septal ablation: a case report and review of literature. | Over the years, alcohol septal ablation has become an effective and well-accepted modality in the treatment of patients with hypertrophic obstructive cardiomyopathy refractory to standard medical therapy. Malignant tachyarrythmias infrequently complicates the procedure and are usually self-terminating. We describe a ca... |
7,014 | Transcatheter closure of atrial septal defect in elderly patients with permanent atrial fibrillation. | The aim of this study is to evaluate the feasibility and efficacy of device closure of atrial septal defect (ASD) in elderly patients with permanent atrial fibrillation.</AbstractText>Little is known about the feasibility of device closure of ASD in those patients.</AbstractText>Nine consecutive patients (mean age 68.1... |
7,015 | Experimental study of the relationship between perfluoro-octyl bromide emulsion and norepinephrine release in reperfusion arrhythmia: isolated guinea pig heart model. | Perfluoro-octyl bromide (PFOB), one of the perfluorochemical oxygen transporters, improved postischemic cardiac dysfunctions. Also norepinephrine (NE) is one of the important inducible factors on reperfusion arrhythmias (ventricular fibrillation [VF]). We used these methods to evaluate the relationship between PFOB emu... |
7,016 | Effect of baroreflex stimulation using phenylephrine injection on ST segment elevation and ventricular arrhythmia-inducibility in Brugada syndrome patients. | Patients affected by Brugada syndrome (BrS) are at risk of sudden cardiac death specifically at rest, when vagal tone is high. The aim of our study was to assess whether a phenylephrine injection, which provokes a baroreflex stimulation, could induce modification of the ST segment elevation and ventricular arrhythmias.... |
7,017 | Impact of cardiac rhythm on mitral valve area calculated by the pressure half time method in patients with moderate or severe mitral stenosis. | The pressure half-time (PHT) method has been widely used to estimate mitral valve area (MVA) in patients with mitral stenosis (MS), in the belief that this simple method provides reliable information on true MVA. However, its limitation has been repeatedly recognized under different circumstances. The aim of this study... |
7,018 | Recent advances in cardiopulmonary resuscitation: cardiocerebral resuscitation. | Cardiocerebral resuscitation (CCR) is a new approach for resuscitation of patients with cardiac arrest. It is composed of 3 components: 1) continuous chest compressions for bystander resuscitation; 2) a new emergency medical services (EMS) algorithm; and 3) aggressive post-resuscitation care. The first 2 components of ... |
7,019 | Cardiac resynchronization therapy and atrial fibrillation. | Cardiac resynchronization therapy (CRT) is an important advance for the treatment of end-stage heart failure (HF). About 15-50% of HF is complicated by atrial fibrillation (AF), associated with worsened outcomes. The presence of AF may interfere with optimal delivery of CRT due to competition with biventricular (BiV) c... |
7,020 | Rapid conversion of persistent atrial fibrillation to sinus rhythm by intravenous AZD7009. | This randomized, double-blind trial compared cardioversion rates between AZD7009 infusion (15-minute 3.25 mg/min, 15-minute 4.4 mg/min, or 30-minute 3.25 mg/min) and placebo infusion (15 or 30 minutes) in patients with atrial fibrillation (AF) scheduled for DC cardioversion. One hundred sixty-eight patients were random... |
7,021 | Taser blunt probe dart-to-heart distance causing ventricular fibrillation in pigs. | The maximum distance between the heart and a model Taser stimulation dart, called the dart-to-heart distance, at which the Taser can directly cause ventricular fibrillation (VF), was measured in pigs. A 9-mm-long blunt probe was advanced snugly through the surrounding tissues toward the heart. Five animals [pig mass=61... |
7,022 | The left atrium, atrial fibrillation, and the risk of stroke in hypertensive patients with left ventricular hypertrophy. | The Losartan Intervention For Endpoint reduction in hypertension (LIFE) study provided extensive data on predisposing factors, consequences, and prevention of atrial fibrillation (AF) in patients with hypertension and left ventricular (LV) hypertrophy. Randomized losartan-based treatment was superior to atenolol-based ... |
7,023 | Vortex filament dynamics in computational models of ventricular fibrillation in the heart. | In three-dimensional cardiac tissue, the re-entrant waves that sustain ventricular fibrillation rotate around a line of phase singularity or vortex filament. The aim of this study was to investigate how the behavior of these vortex filaments is influenced by membrane kinetics, initial conditions, and tissue geometry in... |
7,024 | IK1 heterogeneity affects genesis and stability of spiral waves in cardiac myocyte monolayers. | Previous studies have postulated an important role for the inwardly rectifying potassium current (I(K1)) in controlling the dynamics of electrophysiological spiral waves responsible for ventricular tachycardia and fibrillation. In this study, we developed a novel tissue model of cultured neonatal rat ventricular myocyt... |
7,025 | Diacylglycerol kinase zeta inhibits G(alpha)q-induced atrial remodeling in transgenic mice. | Our previous study showed that diacylglycerol kinase zeta (DGKzeta), which degenerates diacylglycerol (DAG), inhibits ventricular structural remodeling and rescues activated G protein (alpha)q (G(alpha)q)-induced heart failure. However, whether DGKzeta inhibits atrial remodeling is still unknown.</AbstractText>This stu... |
7,026 | Effects of simvastatin on cardiac neural and electrophysiologic remodeling in rabbits with hypercholesterolemia. | Significant cardiac neural and electrophysiologic remodeling occurs with hypercholesterolemia (HC). Whether simvastatin can reverse HC-induced remodeling is unclear.</AbstractText>The purpose of this study was to determine the mechanisms underlying the antiarrhythmic effects of statins.</AbstractText>Rabbits (N = 38) w... |
7,027 | Comparison of beta blocker and digoxin alone and in combination for management of patients with atrial fibrillation and heart failure. | In patients with atrial fibrillation (AF) and heart failure (HF), beta blockers and digoxin reduce the ventricular rate, but controversy exists concerning how these drugs affect prognosis in this setting. This study compared the effects of beta blocker and digoxin on mortality in patients with both AF and HF. In a sing... |
7,028 | Effect of catheter ablation for isolated paroxysmal atrial fibrillation on longitudinal and circumferential left ventricular systolic function. | Isolated paroxysmal atrial fibrillation (AF) is commonly associated with left ventricular (LV) diastolic dysfunction but normal radial systolic contraction. We aim to investigate LV systolic function more precisely using 2-dimensional strain technique in patients with isolated paroxysmal AF and to evaluate evolution of... |
7,029 | Ventricular fibrillation with prominent early repolarization associated with a rare variant of KCNJ8/KATP channel. | Early repolarization in the inferolateral leads has been recently recognized as a frequent syndrome associated with idiopathic ventricular fibrillation (VF). We report the case of a patient presenting dramatic changes in the ECG in association with recurrent VF in whom a novel genetic variant has been identified.</Abst... |
7,030 | [Screening for asymptomatic left ventricular systolic dysfunction in high-risk patients. Preliminary experience with a program based on the use of ECG and natriuretic peptide]. | Patients with asymptomatic left ventricular systolic dysfunction (ALVSD) have an increased risk of heart failure (HF) and a worse life expectancy. Since valuable therapies may prevent such dismal evolution, screening programs for ALVSD have recently been advocated to detect as early as possible such ominous condition. ... |
7,031 | Developmental basis for electrophysiological heterogeneity in the ventricular and outflow tract myocardium as a substrate for life-threatening ventricular arrhythmias. | Reentry is the main mechanism of life-threatening ventricular arrhythmias, including ventricular fibrillation and tachycardia. Its occurrence depends on the simultaneous presence of an arrhythmogenic substrate (a preexisting condition) and a "trigger," and is favored by electrophysiological heterogeneities. In the adul... |
7,032 | Death caused by simultaneous subacute stent thrombosis of sirolimus-eluting stents in left anterior descending artery and left circumflex artery. | Simultaneous drug-eluting stent thrombosis in multivessel disease is a low incidence, but could cause lethal clinical event. We report a case with death caused by simultaneous subacute stent thrombosis of sirolimus-eluting stents in the proximal left anterior descending artery and in the proximal left circumflex artery... |
7,033 | Revelation of Brugada electrocardiographic pattern during a febrile state. | The prevalence of the Brugada-type ECG and its natural history are still unclear. The Brugada syndrome is usually identified by a characteristic Brugada-type ECG that consists of ST elevation of a coved type in the precordial leads V1 to V3 and ventricular fibrillation that can lead to sudden cardiac death, although af... |
7,034 | Functional polymorphisms in ACE and CYP11B2 genes and atrial fibrillation in patients with hypertensive heart disease. | The activated renin-angiotensin-aldosterone system has been reported to play an important role in the pathogenesis of atrial fibrillation (AF). We hypothesized that functional genetic variations of angiotensin-converting enzyme (ACE) and CYP11B2 genes may influence the susceptibility to AF in patients with hypertensive... |
7,035 | Prolonged closed cardiac massage using LUCAS device in out-of-hospital cardiac arrest with prolonged transport time. | Saving more human lives through more effective reanimation measures is the goal of the new international guidelines on cardiopulmonary resuscitation as the decisive aspect for survival after cardiovascular arrest is that basic resuscitation should start immediately. According to the updated guidelines, the greatest eff... |
7,036 | Prolonged Mild-to-Moderate Hypothermia for Refractory Intracranial Hypertension. | Therapeutic hypothermia is an emerging therapy for brain injury and cerebral edema. Hypothermia is known to reduce death and neurologic morbidity in survivors of cardiac arrest from ventricular fibrillation. Traumatic brain injury (TBI) trials studies of short-term hypothermia (24 to 48hours) have had conflicting resul... |
7,037 | Banding and Step-Stair Artifacts on the Cardiac-CT Caused By Pseudo-Ectopic Beats. | Step-stair and banding artifacts may result from irregular ventricular rhythm caused by atrial fibrillation or premature ectopic ventricular contractions. In the case reported here, severe banding and misalignment artifacts occurred due to electrocardiographic noise mimicking ectopic beats. Severe EKG noise or pseudo-e... |
7,038 | Bionic cardiology: exploration into a wealth of controllable body parts in the cardiovascular system. | Bionic cardiology is the medical science of exploring electronic control of the body, usually via the neural system. Mimicking or modifying biological regulation is a strategy used to combat diseases. Control of ventricular rate during atrial fibrillation by selective vagal stimulation, suppression of ischemia-related ... |
7,039 | Sudden cardiac arrest in apical hypertrophic cardiomyopathy. | We present two cases of cardiac arrest, presumably attributable to apical hypertrophic cardiomyopathy(HCM). The first case was a 37-year-old Asian man known to have an apical HCM and was successfully resuscitated from an "out of hospital" ventricular fibrillation arrest. He underwent an electrophysiological study that ... |
7,040 | Choroid plexus papilloma in children: Diagnostic and surgical considerations. | Choroid plexus papilloma (CPP) is a benign neoplasm that arises from the ventricular choroid plexus. The clinical features, radiological characteristics, and treatment have been discussed in this study for a pediatric population.</AbstractText>Over an eight-year period, seven pediatric (≤12 years) CPP patients w... |
7,041 | Differential diagnosis of non-atherosclerotic left main coronary artery stenosis. | A left main coronary artery (LMCA) stenosis without any atherosclerotic changes elsewhere in the coronary artery tree is a rare finding, and some uncommon reasons for luminal narrowing should be considered. An unusual case of non-atherosclerotic LMCA stenosis is reported.A middle-aged patient presented with acute myoca... |
7,042 | Internet diagnosis of digitalis toxicity. | A 65-year-old male with an ischaemic cardiomyopathy and an implantable cardioverter defibrillator got a shock at home. A web-based monitoring system was used to check his device, and the interrogation showed that he had had several episodes of ventricular fibrillation and new onset of complete heart block that required... |
7,043 | Propafenone induced Brugada-like ECG changes mistaken as acute myocardial infarction. | Brugada syndrome is one of the important causes of sudden cardiac death in young adults. The condition is associated with typical electrocardiogram (ECG) changes in anteroseptal leads V1 and V2 that can be unmasked by various medications, electrolyte disturbances, and even by the febrile state in susceptible individual... |
7,044 | Current approaches to cardiopulmonary resuscitation. | Cardiac arrest occurs when there is abrupt cessation of effective pumping activity of the heart. Among the likely causes are ventricular asystole (electrical or mechanical), pulseless ventricular tachycardia or ventricular fibrillation. Clinically this may present as 'sudden cardiac death'. |
7,045 | Effectiveness of a simulation-based medical student course on managing life-threatening medical conditions. | To assess the competency and the comfort level of medical students in lifesaving skills after a simulation-based training session and then determine skill retention after 1 year.</AbstractText>Prospective observational before-after case series of medical students entering the third year. Each student participated in a ... |
7,046 | Consequences of Atrial or Ventricular Tachypacing on the Heat Shock Proteins (HSP) level of Expression and Phosphorylation. | Uncontrolled atrial fibrillation (AF) results in complex changes in the cardiomyocyte electrical and contractile functioning that promote atrial remodeling and the continuation of AF. Recently there has been a growing interest in understanding the role of heat shock proteins (HSPs), which are cytoprotective molecular c... |
7,047 | Initial cardiac rhythm correlated to emergency department survival. | This study attempted to correlate the initial cardiac rhythm and survival from prehospital cardiac arrest, as a secondary end-point.</AbstractText>Prospective, randomized, double-blinded clinical intervention trial where bicarbonate was administered to 874 prehospital cardiopulmonary arrest patients in prehospital urba... |
7,048 | [Histochemical study of the myocardium structure in the heart contusion]. | The experimental modeling of heart contusion which was accompanied by ventricular fibrillation development was performed in Wistar rats, with the electrocardiographic study and subsequent histological and histochemical examination of the myocardium samples. Following heart contusion, acute circulatory disturbances, mus... |
7,049 | The cognitive basis of effective team performance: features of failure and success in simulated cardiac resuscitation. | Despite a body of research on teams in other fields relatively little is known about measuring teamwork in healthcare. The aim of this study is to characterize the qualitative dimensions of team performance during cardiac resuscitation that results in good and bad outcomes. We studied each team's adherence to Advanced ... |
7,050 | Potential application of late sodium current blockade in the treatment of heart failure and atrial fibrillation. | The cardiac action potential consists of the sequential activation of various ion channels in a precisely orchestrated manner. Pathologic alterations of ion channel currents disrupt this coordinated behavior and have been linked to arrhythmias, such as atrial fibrillation, as well as to heart failure. The late sodium c... |
7,051 | Cerebral desaturation during cardiac arrest: its relation to arrest duration and left ventricular pump function. | To determine the impact of brief periods of cardiac arrest (CA) on regional cerebral oxygen saturation (rSO2) in patients with low left ventricular ejection fraction (LVEF <30%).</AbstractText>Prospective observational study.</AbstractText>Cardiac surgery room at a university hospital.</AbstractText>Seventy-seven co... |
7,052 | Arrhythmias and heart rate variability during and after therapeutic hypothermia for cardiac arrest. | To evaluate the effects of therapeutic hypothermia (HT) of 33 degrees C after cardiac arrest (CA) on cardiac arrhythmias, heart rate variability (HRV), and their prognostic value.</AbstractText>Prospective, comparative substudy of a randomized controlled trial of mild HT after out-of-hospital CA, the European Hypotherm... |
7,053 | Unexplained hypotension: the spectrum of dynamic left ventricular outflow tract obstruction in critical care settings. | To illustrate the clinical and hemodynamic abnormalities caused by dynamic left ventricular outflow tract obstruction (LVOTO) in critical care setting.</AbstractText>We reviewed cases referred to Cardiology with echocardiographic evidence of LVOTO and their clinical presentations. We present those cases where LVOTO can... |
7,054 | Role of angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, and aldosterone antagonists in the prevention of atrial and ventricular arrhythmias. | Atrial arrhythmias, ventricular arrhythmias, and sudden cardiac death (SCD) are significant health problems and an economic burden to society. The renin-angiotensin-aldosterone system (RAAS) may play a key role in the occurrence of structural and electrical remodeling, potentially explaining the development of atrial a... |
7,055 | [Genetic predisposition to systemic complications of arterial hypertension in maintenance haemodialysis patients]. | Cardiovascular disease is the most common cause of a high morbidity and mortality in patients on renal replacement therapy and is responsible for about 50% of deaths. Hypertension is the main risk factor for cardiovascular events in the general population as well as in haemodialysed (HD) patients. The hypertension in H... |
7,056 | Chronic heart failure in the elderly: a current medical problem. | As a result of population ageing and improved medical care that contribute to better life expectancy, heart failure occurs more and more commonly in the elderly. In the USA approximately 80% of patients discharged from hospital with newly diagnosed heart failure are over 65 years of age, whereas 50% are over 75. The av... |
7,057 | Atrial fibrillation in patients with implantable defibrillators. | Atrial fibrillation (AF) is common in patients who have implantable defibrillators and presents some unique challenges and opportunities. AF burden can be assessed more accurately, allowing for evaluation of therapy efficacy (drugs or ablation). It remains to be shown whether home monitoring of defibrillators to detect... |
7,058 | Drug therapy for atrial fibrillation. | Atrial fibrillation is the most frequently diagnosed arrhythmia. Prevalence increases with age, and the overall incidence is expected to increase as the population continues to age. Choice of pharmacologic therapy for atrial fibrillation depends on whether or not the goal of treatment is maintaining sinus rhythm or tol... |
7,059 | The impact of therapeutic hypothermia on neurological function and quality of life after cardiac arrest. | To assess the impact of therapeutic hypothermia on cognitive function and quality of life in comatose survivors of out of Hospital Cardiac arrest (OHCA).</AbstractText>We prospectively studied comatose survivors of OHCA consecutively admitted in a 4-year period. Therapeutic hypothermia was implemented in the last 2-yea... |
7,060 | [The influence of anisodamine on cardiopulmonary resuscitation in rat]. | To evaluate the influence of anisodamine (Ani) on restoration of spontaneous circulation (ROSC) and cardiopulmonary resuscitation (CPR) rate in a randomized, blinded experimental study so as to explore a new treatment for CPR.</AbstractText>Forty-five Sprague-Dawley (SD) rats were randomized to three groups: control gr... |
7,061 | [A report of 463 in-hospital cardiopulmonary resuscitation based on the "Utstein Style"]. | Assessment of outcomes and outcome-related factors of in-hospital cardiopulmonary resuscitation (CPR) based on the "Utstein Style".</AbstractText>The study was designed as a prospective, single-institution, registry investigation of 463 patients (included adult and pediatric patients) for whom a CPR was attempted.</Abs... |
7,062 | Sleep-disordered breathing: autonomic mechanisms and arrhythmias. | Obstructive sleep apnea (OSA) is present in at least 2% to 4% of the general population. Central sleep apnea (CSA), though less common, is highly prevalent in patients with heart failure. Both forms of sleep apnea exert strong modulatory effects on the autonomic nervous system at night through a number of mechanisms in... |
7,063 | Spectral analysis of intracardiac electrograms during induced and spontaneous ventricular fibrillation in humans. | Very limited data are available on the differences between spontaneous and induced episodes of ventricular fibrillation (VF) in humans. The aim of the study was to compare the spectral characteristics of the electrical signal recorded by an implantable cardioverter defibrillator (ICD) during both types of episodes.</Ab... |
7,064 | Defibrillator shock due to ventricular trigeminy. | A 56-year-old lady with arrhythmogenic right ventricular cardiomyopathy had a shock for ventricular trigeminy. The device diagnosed this as ventricular fibrillation because of its binning algorithm, which does not use a consecutive, or a proportional counter. A beat is binned as a fibrillation beat only if the current ... |
7,065 | Atrial fibrillation in acute myocardial infarction: a systematic review of the incidence, clinical features and prognostic implications. | Atrial fibrillation (AF), the most commonly encountered clinical arrhythmia, often complicates acute myocardial infarction (AMI) with an incidence between 6 and 21%. Predictors of the arrhythmia in the setting of AMI include advanced age, heart failure symptoms, and depressed left ventricular function. The bulk of evid... |
7,066 | [Radiofrequency ablation of long standing persistent atrial fibrillation and post-incisional macroreentrant right atrial tachycardia in patient with advanced biventricular heart failure--case raport]. | We present a case of a 54 year old male with a long-standing atrial fibrillation (AF) who was scheduled for cardiac transplantation due to the progression of heart failure. Previous treatment included pacemaker implantation, mitral valvuloplasty, a-v node modification using RF ablation, and pharmacological therapy. Thi... |
7,067 | [Proarrhythmic effect of propafenone in patients with atrial fibrillation and atrial flutter]. | We present two cases of proarrhythmia after propafenone treatment. In the first case slowing of the flutter cycle length from 205 ms to 290 ms resulted in a change from well tolerated two to one atrioventricular conduction to one to one conduction with hypotension and presyncope. In the second case organization of atri... |
7,068 | Differential effects of propofol and sevoflurane on ischemia-induced ventricular arrhythmias and phosphorylated connexin 43 protein in rats. | The effects of anesthetics on ischemia-induced ventricular arrhythmias remain poorly studied. This study investigated the effects of propofol and sevoflurane on the survival rate and morbidity as a result of ventricular arrhythmias, and defined a possible mechanism for the arrhythmogenic properties of anesthetics durin... |
7,069 | Safety of pulsed electric devices. | The strength-duration curve for tissue excitation can be modeled by a parallel resistor-capacitor circuit that has a time constant. We tested several short-duration electric generators: five electric fence energizers, the Taser X26 and a high-frequency generator to determine their current-versus-time waveforms. We esti... |
7,070 | Epicardial border zone overexpression of skeletal muscle sodium channel SkM1 normalizes activation, preserves conduction, and suppresses ventricular arrhythmia: an in silico, in vivo, in vitro study. | In depolarized myocardial infarct epicardial border zones, the cardiac sodium channel (SCN5A) is largely inactivated, contributing to low action potential upstroke velocity (V(max)), slow conduction, and reentry. We hypothesized that a fast inward current such as the skeletal muscle sodium channel (SkM1) operating more... |
7,071 | Potential role of home monitoring to reduce inappropriate shocks in implantable cardioverter-defibrillator patients due to lead failure. | Lead dysfunctions in implantable cardioverter-defibrillator (ICD) patients can lead to inappropriate shocks or even complete loss of function of the device. Home monitoring (HM) systems are capable of daily data transmissions regarding the device and the lead integrity as well as information concerning anti-arrhythmic ... |
7,072 | Atrial fibrillation and congestive heart failure. | The present review will examine the prognostic importance of atrial fibrillation and heart failure, explore the different therapeutic options for treating atrial fibrillation and present the results of the Atrial Fibrillation and Congestive Heart Failure (AF-CHF) trial.</AbstractText>The Atrial Fibrillation and Congest... |
7,073 | Mesenchymal stem cells improve outcomes of cardiopulmonary resuscitation in myocardial infarcted rats. | We hypothesized that administration of allogeneic bone marrow mesenchymal stem cells (MSCs) by intravenous, intraventricular or intramyocardial injection could improve myocardial function after survival time after cardiopulmonary resuscitation in myocardial infarcted rats. Myocardial infarction was induced by ligation ... |
7,074 | Long-term outcome after a first episode of heart failure. A prospective 7-year study. | Heart failure (HF) is a major issue of public health in contemporary aging populations. The objectives of the present study were to assess the long-term survival of a contemporary cohort of patients discharged after a first hospitalization for HF and identify variables associated with adverse outcome.</AbstractText>We ... |
7,075 | Distinct contractile and molecular differences between two goat models of atrial dysfunction: AV block-induced atrial dilatation and atrial fibrillation. | Atrial dilatation is an independent risk factor for thromboembolism in patients with and without atrial fibrillation (AF). In many patients, atrial dilatation goes along with depressed contractile function of the dilated atria. While some mechanisms causing atrial contractile dysfunction in fibrillating atria have been... |
7,076 | [Study of the stroke and coronary risks in hypertensive patients over 54 years of age in the primary care practice]. | Quantification of stroke risk is not always performed in hypertensive patients in Primary Care.</AbstractText>This was an epidemiological study in hypertensive patients aged 55 years and older attending primary care centres in Spain. The D'Agostino Stroke Risk Scale, using data from the Framingham Study, was used for a... |
7,077 | [Clinical features of unexpected sudden death clustered in 7 families in Yunnan Province]. | To investigate the clinical features of unexpected sudden death (SUD) clustered in families in Yunnan province.</AbstractText>This retrospective study analyzed the clinical features of SUD occurred between July to September 2005 in 7 families in Yunnan province.</AbstractText>All 16 SUD patients shared common clinical ... |
7,078 | [Prognostic value of microvolt level T-wave alternans in patients at high risk of sudden cardiac death]. | To explore the predict value of microvolt level T-wave alternans (MTWA) for malignant ventricular arrhythmia (MVA) and sudden cardiac death (SCD) in high risk patients.</AbstractText>A total of 105 healthy subjects (control group) and 138 patients with history of VT or VF or patients with LVEF < or = 45% (SCD high r... |
7,079 | [Transient change of cardiac action potential and intracellular Ca2+ during ventricular fibrillation]. | The cardiac action potential (AP) and the intracellular Ca(2+) transient (CaT) are closely associated under normal physiological conditions, but not during ventricular fibrillation (VF). The purpose of this study was to determine whether this dissociation is directly related to the higher activation rate during VF.</Ab... |
7,080 | [Transmural heterogeneity of calcium handling proteins in the mechanism of porcine model of ventricular fibrillation]. | To investigate the role of heterogeneous expression of calcium handling proteins and spatial heterogeneity of APD restitution in the maintenance mechanism of ventricular fibrillation.</AbstractText>During programmed electrical simulation, APD restitution curves in the endocardium and epicardium of LV were constructed b... |
7,081 | [The prospective study on the prognosis in patients with ventricular tachycardia or fibrillation treated with implantable automatic cardioverter defibrillator]. | To explore the effect of implantable automatic cardioverter defibrillator (ICD) on improvement of the prognosis of patients with ventricular tachycardia or fibrillation (VT/VF). To compare the advantages and disadvantages of ICD with antiarrhythmic drug, to select the best indication of ICD and review the protocol of t... |
7,082 | DDESC: Dragon database for exploration of sodium channels in human. | Sodium channels are heteromultimeric, integral membrane proteins that belong to a superfamily of ion channels. The mutations in genes encoding for sodium channel proteins have been linked with several inherited genetic disorders such as febrile epilepsy, Brugada syndrome, ventricular fibrillation, long QT syndrome, or ... |
7,083 | Nitroglycerin and epinephrine improve coronary perfusion pressure in a porcine model of ventricular fibrillation arrest: a pilot study. | Cardiac arrest remains one of the leading causes of death worldwide. European Resuscitation Council Guidelines for Resuscitation 2005 recommend epinephrine for its treatment.</AbstractText>To estimate whether the administration of a vasodilatator such as nitroglycerin in combination with epinephrine during cardiopulmon... |
7,084 | Demonstration of a very rare coronary anomaly with multislice computed tomography: arising of right coronary artery from left anterior descending artery. | Arising of right coronary artery from left anterior descending artery is a very rare anomaly. We present a case with this anomaly that was also demonstrated with multislice computed tomography. |
7,085 | Spatial and temporal organization of the dominant frequencies in the fibrillating heart: body surface potential mapping in a rare case of sustained human ventricular fibrillation. | The aim of this study was to assess the spatial and temporal variability of dominant fibrillation frequencies in a rare case of sustained human ventricular fibrillation (VF).</AbstractText>Body surface potential mapping was performed in a patient with sustained VF and who was supported by a biventricular assist device.... |
7,086 | Induction of ventricular fibrillation rather than ventricular tachycardia predicts tachyarrhythmia recurrences in patients with idiopathic dilated cardiomyopathy and implantable cardioverter defibrillator for secondary prophylaxis. | We sought to investigate the association of inducibility of polymorphic ventricular tachycardia or ventricular fibrillation (PVT/VF) or sustained monomorphic ventricular tachycardia (SMVT) at standardized programmed ventricular stimulation (PVS) with the long-term likelihood of sudden death and/or fast VT in a large co... |
7,087 | [Experiences on surgical treatment of severe aortic valve stenosis: a report of 171 cases]. | To analyze the experiences on surgical treatment of severe aortic valve stenosis.</AbstractText>From December 1990 to December 2006, 171 patients with severe aortic valve stenosis underwent aortic valve replacement (AVR). There were 135 males and 36 females aged from 10 to 75 years old, with a mean of (45.8 +/- 15.6) y... |
7,088 | The intriguing problem of atrial fibrillation in competitive athletes. | Atrial fibrillation (AF) is the most frequent cause of prolonged palpitations in young competitive athletes, even including those performing elite sport activity. This arrhythmia may occasionally affect impair athletes' ability to compete thus leading to non-eligibility at prequalification screening. Competitive sport ... |
7,089 | The significance of cardiac sympathetic nervous system abnormality in the long-term prognosis of patients with a history of ventricular tachyarrhythmia. | Severe left ventricular dysfunction or cardiac sympathetic nervous system (SNS) abnormality predicts cardiac death in various heart diseases, including arrhythmogenic disorders. However, it is not clear whether SNS abnormality predicts sudden cardiac death during long-term follow-up in patients with a history of ventri... |
7,090 | Timing of defibrillation shocks for resuscitation of rapid ventricular tachycardia: does it make a difference? | Under current resuscitation guidelines symptomatic ventricular tachycardia (VT) with a palpable pulse is treated with synchronised cardioversion to avoid inducing ventricular fibrillation (VF), whilst pulseless VT is treated as VF with rapid administration of full defibrillation energy unsynchronised shocks. The additi... |
7,091 | Multiple cardiac thrombi and thromboembolism in a heparin-induced thrombocytopenia antibody-positive patient with heart failure. | A 49-year-old Japanese man presented with orthopnea and edema in both legs. He was diagnosed with congestive heart failure with triple-vessel coronary artery disease. Low antithrombin and left ventricular systolic dysfunction were possible causes of his hypercoagulable state. Echocardiography revealed thrombi in the le... |
7,092 | Sex differences in the hypertensive population with chronic ischemic heart disease. | Cardiopatía Isquémica Crónica e Hipertensión Arterial en la Práctica Clínica en España (CINHTIA) was a survey designed to assess the clinical management of hypertensive outpatients with chronic ischemic heart disease. Sex differences were examined. Blood pressures (BP) was considered ... |
7,093 | Therapeutic hypothermia in Italian intensive care units: a national survey. | The aim of this study was to investigate the use of therapeutic hypothermia (TH) in Italian Intensive Care Units (ICUs).</AbstractText>After being contacted by phone, a structured questionnaire to evaluate the use of TH was sent to all Italian ICUs. The questionnaire was aimed at determining the extent of TH use (indic... |
7,094 | Biophysical characterization of the short QT mutation hERG-N588K reveals a mixed gain-and loss-of-function. | The short QT syndrome is a newly discovered pro-arrhythmic condition, which may cause ventricular fibrillation and sudden death. Short QT can originate from the apparent gain-of-function mutation N588K in the hERG potassium channel that conducts repolarising I(Kr) current. The present study describes a profound biophys... |
7,095 | Levosimendan and calcium sensitization of the contractile proteins in cardiac muscle: impact on heart failure. | Levosimendan increases the sensitivity of the cardiac fibrils to calcium, favorably affects hemodynamics in patients with heart failure. It is a positive inotrope and a peripheral vasodilator. The elimination half-life of the compound is about 1 hour. The drug decreases pulmonary capillary wedge pressure, increases car... |
7,096 | [Arterial hypertension and cardiac arrhythmias]. | VENTRICULAR ARRHYTHMIAS: Different factors--like hypertrophy, fibrosis, ischemia and apoptosis increase the risk of ventricular arrhythmias and sudden arrhythmic death. ACE inhibitors and Angiotensin receptor antagonists offer a curative therapeutic approach. Beta-blocker are strongly recommended. Amiodarone may be use... |
7,097 | Atrial-selective effects of chronic amiodarone in the management of atrial fibrillation. | Although amiodarone is one of the most effective pharmacologic agents used in clinical management of atrial fibrillation (AF), little is known about its differential effects in atrial and ventricular myocardium.</AbstractText>This study sought to compare the electrophysiological effects of chronic amiodarone in atria a... |
7,098 | Role of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidine. | Quinidine is used to treat atrial fibrillation and ventricular arrhythmias. However, at low concentrations, it can induce torsade de pointes (TdP).</AbstractText>The purpose of this study was to examine the role of late sodium current (I(Na)) as a modulator of the arrhythmogenicity of quinidine in female rabbit isolate... |
7,099 | Prevalence of early repolarization pattern in inferolateral leads in patients with Brugada syndrome. | Recent data have shown a high incidence of the early repolarization pattern confined in inferolateral leads in patients with idiopathic ventricular fibrillation.</AbstractText>The purpose of the present study was to investigate the prevalence and the prognostic significance of the early repolarization pattern in infero... |
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