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8,900
Aortic valve sclerosis: is it a cardiovascular risk factor or a cardiac disease marker?
Aortic valve sclerosis, without stenosis, has been associated with an increased cardiovascular mortality and morbidity due to myocardial infarction. However, it is unclear whether it is a cardiovascular risk factor or a cardiac disease marker. The goal of our study is to evaluate the difference in the prevalence of car...
8,901
Beneficial effects of terlipressin in prolonged pediatric cardiopulmonary resuscitation: a case series.
Arginine vasopressin was found in experimental and clinical studies to have a beneficial effect in cardiopulmonary resuscitation. The American Heart Association 2000 guidelines recommended its use for adult ventricular fibrillation arrest, and the American Heart Association 2005 guidelines noted that it may replace the...
8,902
Simultaneous ST-segment elevation in the right precordial and inferior leads in Brugada syndrome.
We report the case of a patient with genetically confirmed Brugada syndrome who presented with ST-segment elevation in the right precordial and inferior leads. The presenting arrhythmia was atrial fibrillation, which degenerated into ventricular fibrillation during intravenous amiodarone. A flecainide test was markedly...
8,903
The recent evolution of coronary care units into intensive cardiac care units: the experience of a tertiary center in Florence.
To evaluate the evolution of intensive cardiac care units (ICCUs) in the third millenium by assessing the activity and the workload of our ICCU which is a Hub center, from 1 January 2004 to 30 June 2005.</AbstractText>Among the 1397 patients consecutively admitted to our ICCU, 40.5% came from Spokes. Patients with ST e...
8,904
Tachycardia-induced cardiomyopathy: mechanisms of heart failure and clinical implications.
The prognosis of dilated cardiomyopathy is generally poor. The cause of ventricular dysfunction often cannot be identified. In most cases, the clinical history of cardiomyopathy is irreversible but, in some cases, potentially curable causes may be identified. The development of cardiomyopathy may be correlated to atria...
8,905
Pulse pressure and risk of new-onset atrial fibrillation.
Atrial fibrillation (AF) is responsible for considerable morbidity and mortality, making identification of modifiable risk factors a priority. Increased pulse pressure, a reflection of aortic stiffness, increases cardiac load and may increase AF risk.</AbstractText>To examine relations between pulse pressure and incide...
8,906
Automated review of electronic health records to assess quality of care for outpatients with heart failure.
Electronic health records (EHRs) may be used to assess quality of care.</AbstractText>To evaluate the accuracy of automated review of EHR data to measure quality of care for outpatients with heart failure.</AbstractText>Observational study of quality of care for heart failure comparing automated review of EHR data with...
8,907
Chronic health conditions and survival after out-of-hospital ventricular fibrillation cardiac arrest.
To investigate whether chronic clinical comorbidity, as collected from emergency medical services (EMS) reports, influences survival after out-of-hospital ventricular fibrillation (VF) cardiac arrest.</AbstractText>In this observational retrospective cohort study in King County, Washington, USA 1043 people who suffered...
8,908
Lower body mass index and atrial fibrillation as independent predictors for mortality in patients with implantable cardioverter defibrillator.
To evaluate risk factors related to total mortality in an unselected population of patients implanted with a cardioverter defibrillator.</AbstractText>Survival analysis was performed retrospectively investigating the records of 77 consecutive patients implanted with defibrillators (median 67 years, range 38-83 years; 6...
8,909
The cardioprotective effects of thoracal epidural anestesia are induced by the expression of vascular endothelial growth factor and inducible nitric oxide synthase in cardiopulmonary bypass surgery.
The cardioprotective effects of thoracal epidural anesthesia (TEA) are induced by the expression of vascular endothelial growth factor (VEGF) and inducible nitric oxide synthase (i-NOS) in cardiopulmonary bypass (CPB) surgery. When general anaesthesia (GA) is combined with TEA during coronary artery bypass graft, we in...
8,910
Effects of early afterdepolarizations on reentry in cardiac tissue: a simulation study.
Early afterdepolarizations (EADs) are classically generated at slow heart rates when repolarization reserve is reduced by genetic diseases or drugs. However, EADs may also occur at rapid heart rates if repolarization reserve is sufficiently reduced. In this setting, spontaneous diastolic sarcoplasmic reticulum (SR) Ca ...
8,911
Troponin I and lactate from coronary sinus predict cardiac complications after myocardial revascularization.
Postoperative troponin I and lactate elevation are related to cardiac complications after myocardial revascularization. We sought to evaluate earlier predictive value for acute myocardial infarction (AMI) and myocardial damage of troponin I and lactate after myocardial revascularization.</AbstractText>In all, 183 conse...
8,912
Effect of oral beta-blocker therapy on microvolt T-wave alternans and electrophysiology testing in patients with ischemic cardiomyopathy.
Prior investigation has shown that intravenous beta-blockers decrease T-wave alternans (TWA) positivity in patients undergoing electrophysiology study (EPS). The present study examined whether oral beta-blocker use within 24 hours of TWA influences yield and predictive value of TWA and EPS.</AbstractText>We prospective...
8,913
Aortic valve surgery in octogenarians: predictive factors for operative and long-term results.
To assess factors influencing operative and long-term outcome in octogenarians undergoing aortic valve surgery (AVR).</AbstractText>Records of 220 consecutive octogenarians having AVR between 1992 and 2004 were reviewed, and follow-up obtained (99% complete). Of the group (mean age: 82.8 years; 174 females), 142 patien...
8,914
An unconditionally stable numerical method for the Luo-Rudy 1 model used in simulations of defibrillation.
Numerical simulations of defibrillation using the Bidomain model coupled to a model of membrane kinetics represent a serious numerical challenge. This is because very high voltages close to defibrillation electrodes demand that extreme time step restrictions be placed on standard numerical schemes, e.g. the forward Eul...
8,915
[Emergent coronary artery bypass grafting in a survivor of out-of-hospital cardiac arrest].
We report a case of emergent coronary artery bypass grafting (CABG) in a survivor of an out-of-hospital cardiac arrest. A 64-year-old male driver lost consciousness and collapsed in a rice paddy field. A bystander placed him in a car and immediately started cardiopulmonary resuscitation after confirming the presence of...
8,916
Novel anti-arrhythmic agents for the treatment of atrial fibrillation.
During atrial fibrillation, abnormal high-frequency activation induces 'remodeling' of the atrial myocardium, which includes changes in both electrical and structural properties. Substantial progress in understanding the molecular determinants underlying atrial fibrillation has led to the development of drugs that coul...
8,917
Noncompaction and endocarditis in suspected mitochondrial disorder.
To report the echocardiographic and autopsy findings of left ventricular hypertrabeculation (LVHT), also known as noncompaction, in a patient with central and peripheral nervous system disease, who died shortly after diagnosing noncompaction.</AbstractText>In a 75 year old woman with cognitive decline, Parkinson syndro...
8,918
Prevalence and characteristics of left atrial tachycardia following left atrial catheter ablation.
Left atrial tachycardia (AT) is a complication of left atrial catheter ablation (LACA) of atrial fibrillation (AF). However, its prevalence and characteristics have not been sufficiently clarified.</AbstractText>We divided 121 patients who underwent LACA into 2 groups based on the results of AT occurrence after LACA (f...
8,919
Thresholds and complications with right ventricular septal pacing compared to apical pacing.
Right ventricular septal pacing has been proposed as an alternative to apical pacing. However, data concerning thresholds and requirement for lead repositioning with this technique are scant.</AbstractText>We reviewed data at implantation and follow-up of 362 consecutive recipients of the same model of active fixation ...
8,920
Dynamic and dual-site atrial pacing in the prevention of atrial fibrillation: The STimolazione Atrial DInamica Multisito (STADIM) Study.
The impact of new algorithms to consistently pace the atrium on the prevention of atrial fibrillation (AF) remains unclear. Our randomized, crossover study compared the efficacy of single- and dual-site atrial pacing, with versus without dynamic atrial overdrive pacing in preventing AF.</AbstractText>We studied 72 pati...
8,921
AAIsafeR limits ventricular pacing in unselected patients.
Dedicated pacing modes, such as AAIsafeR, prevent ventricular (V) pacing in selected patients. We report our experience in consecutive unselected patients.</AbstractText>All data collected in recipients of Symphony DR 2550 pacemakers (ELA Medical, Montrouge, France) were retrospectively analyzed. At each visit, the per...
8,922
Heart rate turbulence after atrial premature complexes depends on coupling interval and atrioventricular nodal conduction.
Positive Turbulence onset (TO) after atrial premature complexes (APCs) was found temporally related to spontaneous episodes of atrial fibrillation. This study tested the hypothesis that heart rate turbulence (HRT) after APCs is influenced by APC prematurity independently of the prematurity of conducted ventricular comp...
8,923
Outcomes of elderly recipients of implantable cardioverter defibrillators.
To examine the patterns of use, complication rates, and survival in elderly recipients of implantable cardioverter defibrillators (ICD).</AbstractText>We followed 500 consecutive patients included in the Marburg Defibrillator database for 48+/-39 months. There were 40 patients (8%) &gt;/= 75 and 460 (92%) &lt; 75 years...
8,924
Maximum ventricular dyssynchrony predicts clinical improvement and reverse remodeling during cardiac resynchronization therapy.
Tissue synchronization imaging (TSI) and tissue tracking imaging (TTI) might facilitate the evaluation of ventricular dyssynchrony.</AbstractText>In 22 patients, TSI and TTI were performed before and &lt; 1 month after onset of cardiac resynchronization therapy (CRT). With TSI guidance, maximum left ventricular (LV) in...
8,925
Prevention of inappropriate shocks in ICD recipients: a review of 10,000 tachycardia episodes.
The efficacy of dual-chamber ICD arrhythmia classification algorithms is crucial to prevent inappropriate shocks. We report our experience from a meta-analysis of five prospective clinical studies with inclusion phases ranging between 1997 and 2003.</AbstractText>Dual-chamber ICD using standard dual-chamber arrhythmia ...
8,926
Clinical predictors of appropriate implantable-cardioverter defibrillator discharge.
The implantable cardioverter-defibrillator (ICD) is the mainstay of treatment for ventricular tachyarrhythmias due to its impact on mortality. ICD discharges may be appropriate or inappropriate, and identification of patients at risk for ICD discharge is essential. We sought to determine the predictors of appropriate I...
8,927
Unusual balloon rupture during direct stenting with a TaxusExpress stent in a venous graft complicated by vessel rupture: a device-related fatal event.
A 70-year-old male with a prior coronary artery bypass operation presented with increasing episodes of chest pain. Coronary angiography revealed severe disease of the left anterior descending artery (LAD), CX, and RCA. A left internal mammary artery to LAD was patent. A jump venous graft, with four distal anastomoses, ...
8,928
Wolf-parkinson-white syndrome presented with broad QRS complex tachycardia.
Broad QRS complex tachycardia is tachycardia with widened QRS complex more than 12 s and caused by various mechanisms, either supraventricular or ventricular. It is important to differentiate between ventricular and supraventricular because it will determine treatment and prognosis of patients. We report a case which w...
8,929
Electrocautery-induced ventricular tachycardia and fibrillation during device implantation and explantation.
Electrocautery is commonly employed during surgical implantation and explantation of pacemakers and implantable cardioverter-defibrillators (ICDs). Four cases of electrocautery-induced ventricular tachyarrhythmias including ventricular tachycardia (VT) or ventricular fibrillation (VF) during device implantation or expl...
8,930
Echocardiography and carotid sonography in diabetic patients after cerebrovascular attacks.
This study evaluated the aetiological factors for cerebrovascular attack (CVA) using echocardiography and sonography of the carotid arteries. Results from 253 patients with CVA were evaluated retrospectively and analysed according to the presence or absence of diabetes and atrial fibrillation. In patients with sinus rh...
8,931
Nitric oxide fails to confer endogenous antiarrhythmic cardioprotection in the primate heart in vitro.
The role of nitric oxide (NO) in cardiac pathophysiology remains controversial. According to data from several studies using rat and rabbit isolated hearts, NO is an endogenous cardioprotectant against reperfusion-induced ventricular fibrillation (VF). Thus, if cardiac NO production is abolished by perfusion with L-N(G...
8,932
Diastolic dysfunction in heart failure with preserved systolic function: need for objective evidence:results from the CHARM Echocardiographic Substudy-CHARMES.
We tested the hypothesis that diastolic dysfunction (DD) was an important predictor of cardiovascular (CV) death or heart failure (HF) hospitalization in a subset of patients (ejection fraction [EF] &gt;40%) in the CHARM-Preserved study.</AbstractText>More than 40% of hospitalized patients with HF have preserved systol...
8,933
Resuscitation outcomes comparing year 2000 with year 2005 ALS guidelines in a pig model of cardiac arrest.
Ventricular fibrillation remains the leading cause of death in western societies. International organizations publish guidelines to follow in case of cardiac arrest. The aim of the present study is to assess whether the newly published guidelines record similar resuscitation success with the 2000 Advanced Life Support ...
8,934
Arterial base excess after CPR: the relationship to CPR duration and the characteristics related to outcome.
We aimed (1) to determine the relationship between arterial base excess (BE) immediately after the restoration of spontaneous circulation (ROSC) and duration of cardiopulmonary resuscitation (CPR) and (2) to ascertain the value of admission BE data as a predictor of mortality in patients resuscitated from cardiac arres...
8,935
Value of VDD-pacing systems in patients with atrioventricular block: experience over a decade.
Even though current guidelines suggest the use of VDD pacemakers in patients with AV block and normal sinus node function, a DDD system is often preferred for fear of either long-term atrial undersensing or late sinus node dysfunction and the resultant need for system upgrades.</AbstractText>We evaluated the long-term ...
8,936
[Relationship between sympathetic remodeling and electrical remodeling at infarcted border zone of rabbit with chronic myocardial infarction].
To investigate the relationship between sympathetic remodeling and electrical remodeling at the infarcted border zone (IBZ) of rabbit with chronic myocardial infarction (MI).</AbstractText>Thirty rabbits were randomly assigned into two groups: MI group (n = 20): ligation of the anterior descending coronary; sham operat...
8,937
Potential mechanisms of stroke benefit favoring losartan in the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study.
The Losartan Intervention For Endpoint reduction in hypertension (LIFE) study is the first, and, so far, the only endpoint trial in patients with hypertension and left ventricular hypertrophy (LVH) to show a divergent therapeutic outcome of one treatment modality over another with equivalent blood pressure control. The...
8,938
Addendum to "Personal and public safety issues related to arrhythmias that may affect consciousness: implications for regulation and physician recommendations: a medical/scientific statement from the American Heart Association and the North American Society of Pacing and Electrophysiology": public safety issues in pati...
In 1996, the American Heart Association developed a scientific statement entitled "Personal and Public Safety Issues Related to Arrhythmias That May Affect Consciousness: Implications for Regulation and Physician Recommendations." Since then, multiple trials have established the role of implantable cardioverter-defibri...
8,939
Prediction of countershock success using single features from multiple ventricular fibrillation frequency bands and feature combinations using neural networks.
Targeted defibrillation therapy is needed to optimise survival chances of ventricular fibrillation (VF) patients, but at present VF analysis strategies to optimise defibrillation timing have insufficient predictive power. From 197 patients with in-hospital and out-of-hospital cardiac arrest, 770 electrocardiogram (ECG)...
8,940
Implantable cardiac defibrillator placement in a patient with persistent left superior vena cava and Brugada syndrome.
A 45-year-old man was diagnosed with new-onset atrial fibrillation. Control of ventricular rate led to spontaneous conversion to sinus rhythm. Subsequent electrocardiograms revealed ST segment changes characteristic of Brugada syndrome. Electrophysiology study demonstrated inducible ventricular fibrillation. During the...
8,941
Association of electrocardiographic abnormalities with cardiac findings and neuromuscular disorders in left ventricular hypertrabeculation/non-compaction.
Left ventricular hypertrabeculation/non-compaction (LVHT) is a cardiac abnormality characterized by prominent trabeculations and intertrabecular recesses, and frequently associated with neuromuscular disorders (NMD). The aim of the study was to assess the prevalence of electrocardiographic (ECG) abnormalities in LVHT a...
8,942
Role of the implantable defibrillator among elderly patients with a history of life-threatening ventricular arrhythmias.
The implantable defibrillator (ICD) reduces arrhythmic and all-cause mortality in patients with a history of life-threatening ventricular arrhythmias. However, its effectiveness in elderly patients is uncertain, given their competing risk of non-arrhythmic death.</AbstractText>Individual patient data from all three sec...
8,943
The effect of preoperative atrial fibrillation on survival following mitral valve repair for degenerative mitral regurgitation.
There is conflicting evidence with regard to the impact of preoperative atrial fibrillation (AF) on the post mitral valve (MV) repair on the early and late outcome.</AbstractText>A total of 349 patients undergoing various MV repair procedures for degenerative mitral regurgitation (MR) between 1997 and 2003 were studied...
8,944
The interaction of interventricular pacing intervals and left ventricular lead position during temporary biventricular pacing evaluated by tissue Doppler imaging.
To determine the effects of interventricular pacing interval and left ventricular (LV) pacing site on ventricular dyssynchrony and function at baseline and during biventricular pacing, using tissue Doppler imaging.</AbstractText>Using an angioplasty wire to pace the left ventricle, 20 patients with heart failure and le...
8,945
Holter monitoring for 24 hours in patients with thromboembolic stroke and sinus rhythm diagnosed in the emergency department.
It is well known that patients with ischemic stroke show ST-T abnormalities and various rhythm abnormalities on an electrocardiogram (ECG). The most commonly encountered rhythm abnormality is atrial fibrillation. It was recently shown that paroxysmal atrial fibrillation (PAF) is an important causative factor in patient...
8,946
Electrophysiologic characteristics and outcome of segmental ostial superior vena cava isolation in patients with paroxysmal atrial fibrillation initiated by superior vena cava ectopy: comparison with pulmonary vein isolation.
This study investigated the electrophysiologic characteristics and outcome of superior vena cava (SVC) segmental ostial isolation (SOI) in patients with SVC-initiated paroxysmal atrial fibrillation (PAF).</AbstractText>Ninety-five patients with PAF underwent pulmonary vein (PV) SOI using a basket catheter whether the P...
8,947
Gender-related differences in presentation, treatment, and outcome of patients with atrial fibrillation in Europe: a report from the Euro Heart Survey on Atrial Fibrillation.
This study sought to investigate gender-related differences in patients with atrial fibrillation (AF) in Europe.</AbstractText>Gender-related differences may play a significant role in AF.</AbstractText>We analyzed the data of 5,333 patients (42% female) enrolled in the Euro Heart Survey on Atrial Fibrillation.</Abstra...
8,948
Atrioventricular junction ablation combined with either right ventricular pacing or cardiac resynchronization therapy for atrial fibrillation: the need for large-scale randomized trials.
Nonrandomized studies suggest that atrioventricular (AV) junction ablation and pacemaker implantation may improve quality of life, ejection fraction, and exercise tolerance in patients with symptomatic drug-refractory atrial fibrillation.</AbstractText>The purpose of this study was to determine whether recent randomize...
8,949
Hyperkalemia and cardiac arrest following succinylcholine administration in a 16-year-old boy with acute nonlymphoblastic leukemia and sepsis.
To report a case of potentially lethal hyperkalemia related to succinylcholine administration.</AbstractText>Case report.</AbstractText>A 13-bed pediatric intensive care unit in a tertiary level, university-based children's hospital.</AbstractText>A 16-yr-old boy treated in the intensive care unit due to Klebsiella pne...
8,950
Remodelling of action potential and intracellular calcium cycling dynamics during subacute myocardial infarction promotes ventricular arrhythmias in Langendorff-perfused rabbit hearts.
We hypothesize that remodelling of action potential and intracellular calcium (Ca(i)) dynamics in the peri-infarct zone contributes to ventricular arrhythmogenesis in the postmyocardial infarction setting. To test this hypothesis, we performed simultaneous optical mapping of Ca(i) and membrane potential (V(m)) in the l...
8,951
Fetal atrial flutter: a case report and experience of sotalol treatment.
Fetal tachyarrhythmia may cause fetal hydrops and lead to fetal morbidity and mortality. Supraventricular tachycardia and atrial flutter have been the most diagnosed. We present a case of fetal atrial flutter diagnosed during the second trimester treated with digoxin and sotalol and delivered at term.</AbstractText>A 3...
8,952
Comparison of hands-off time during CPR with manual and semi-automatic defibrillation in a manikin model.
Rhythm analysis with current semi-automatic external defibrillators (AEDs) requires mandatory interruptions of chest compressions that may compromise the outcome after cardiopulmonary resuscitation (CPR). We hypothesised that interruptions would be shorter when the defibrillator was operated in manual mode by trained a...
8,953
Effects of simvastatin on the development of the atrial fibrillation substrate in dogs with congestive heart failure.
Congestive heart failure (CHF) is a common cause of atrial fibrillation (AF). Oxidative stress and inflammation (profibrotic) and peroxisome proliferator-activated receptor-alpha (PPAR-alpha, antifibrotic) factors may be involved in CHF-related remodeling. We evaluated the effects of simvastatin (antioxidant, anti-infl...
8,954
Left ventricular geometry and renal function in hypertensive patients with diastolic heart failure.
The objective is to define the relationship between cardiac geometry and renal function in hypertensive subjects with and without diastolic heart failure (DHF).</AbstractText>This is a prospective observational study in a tertiary-care teaching institute in a 15-month period of consecutive hospitalized hypertensive pat...
8,955
Association of atrial fibrillation in patients with interatrial block over prospectively followed controls with comparable echocardiographic parameters.
Interatrial block (IAB) (P wave &gt;or=110 ms) is a potential risk of atrial fibrillation (AF). However, few investigations have assessed the relevance of echocardiographic parameters, particularly the contribution of its known correlate, left atrial enlargement in this regard. We identified 32 consecutive patients wit...
8,956
Changing capacity of electrocardiographic ventricular repolarization in post-myocardial infarction patients with and without nonfatal cardiac arrest.
Prolonged and labile ventricular repolarization and decreased heart rate variability may be associated with susceptibility to ventricular fibrillation (VF) after myocardial infarction (MI). The response of ventricular repolarization related to abrupt heart rate changes may also be associated with arrhythmia vulnerabili...
8,957
Neutrophil ablation with anti-serum does not protect against phase 2 ventricular arrhythmias in anaesthetised rats with myocardial infarction.
Arrhythmias, including ventricular fibrillation (VF), occur in two phases after coronary obstruction, the first during the reversible stage of acute myocardial ischaemia (phase 1) and the second during evolution of the infarct (phase 2). We tested the hypothesis that phase 2 arrhythmias are mediated by actions of neutr...
8,958
The functional status and perceived quality of life in long-term survivors of out-of-hospital cardiac arrest.
Limited data exist on how long-term survivors after pre-hospital cardiac arrest lead their lives. This study assessed functional status and perceived quality of life in patients surviving for 15 years after successful resuscitation from witnessed out-of-hospital cardiac arrest as a result of ventricular fibrillation.</...
8,959
Detecting ventricular fibrillation by time-delay methods.
A pivotal component in automated external defibrillators (AEDs) is the detection of ventricular fibrillation (VF) by means of appropriate detection algorithms. In scientific literature there exists a wide variety of methods and ideas for handling this task. These algorithms should have a high detection quality, be easi...
8,960
Ventricular fibrillation in myopathic human hearts: mechanistic insights from in vivo global endocardial and epicardial mapping.
Ventricular fibrillation (VF) is an important cause of sudden cardiac death and cardiovascular mortality in patients with cardiomyopathy. Although it was generally believed that chaotic reentrant wavefronts underlie VF in humans, there is emerging evidence of spatiotemporal organization during early VF. The mechanism o...
8,961
Assessment of a three-phase model of out-of-hospital cardiac arrest in patients with ventricular fibrillation.
Cardiac arrest with ventricular fibrillation (VF) has been divided into three phases in which phase-specific therapy may improve outcome. The aim of this study was to assess the relationship between call-to-shock time, bystander CPR (BCPR), and cardiac arrest outcomes.</AbstractText>In a retrospective analysis of prosp...
8,962
Adults undergoing cardiac surgery at a children's hospital: an analysis of perioperative morbidity.
Limited data exist regarding the perioperative morbidity profile of adults who have cardiac operations at pediatric facilities.</AbstractText>A retrospective review (January 2000 to December 2004) of patients (aged 18 years or older) who underwent cardiac surgery at our pediatric institution was performed.</AbstractTex...
8,963
Early antithrombotic therapy for aortic valve bioprostheses: is there an indication for routine use?
Consensus reports over the past 10 years from the United States, Europe, United Kingdom, and Canada have not provided consistent guidelines for antithrombotic therapy of aortic valve bioprostheses for the three-month period after surgery. This study was conducted to determine if antithrombotic therapy was protective ag...
8,964
Intraoperative epicardial electrophysiologic mapping and isolation of autonomic ganglionic plexi.
Autonomic ganglionic plexi (GPs) have been implicated as triggers in lone atrial fibrillation (AF). The purpose of this study was to describe the technique and results of epicardial electrophysiologic mapping and the early effects of GP isolation.</AbstractText>Intraoperative epicardial electrophysiologic mapping was p...
8,965
Do cardiac neuropeptides play a role in the occurrence of atrial fibrillation after coronary bypass surgery?
One of the potential mechanisms to explain the occurrence of postoperative atrial fibrillation (AF) is imbalance of autonomic nervous system tone. The myocardium is innervated not only by cholinergic and adrenergic nerves but also by peptidergic nerves that synthesize and secrete neuropeptides. To investigate the possi...
8,966
Successful extracorporeal life support in cardiac arrest with recurrent ventricular fibrillation unresponsive to standard cardiopulmonary resuscitation.
Extracorporeal life support has been used as an extension of conventional cardiopulmonary resuscitation (CPR). However, the appropriate indications for extracorporeal CPR (ECPR) including the duration of CPR are unknown. We present a case of a male, 37-year-old out-of-hospital cardiac arrest patient who received prolon...
8,967
Prognostic role of B-type natriuretic peptide in patients with diabetes and acute decompensated heart failure.
Several studies have reported the prognostic value of natriuretic peptides, but their predictive value in patients with diabetes mellitus is unknown. The aim of the study was to test the hypothesis that measurement of brain natriuretic peptide (BNP) levels in ambulatory patients with congestive heart failure (CHF) and ...
8,968
Coronary sinus and fossa ovalis ablation: effect on interatrial conduction and atrial fibrillation.
Interatrial conduction occurs via discrete pathways along the coronary sinus musculature, fossa ovalis region, and Bachman's bundle. We assessed the feasibility of altering interatrial conduction by selectively ablating two of these conduction pathways using a novel mesh electrode ablation catheter.</AbstractText>Circu...
8,969
Cardiac resynchronization therapy: predictive factors of unsuccessful left ventricular lead implant.
Cardiac resynchronization therapy is an established therapy for advanced heart failure. However, coronary sinus access and pacing is not achieved in about 5-10% of patients. The aim of this study was to identify predictive factors for failure of left ventricular (LV) lead transvenous implant.</AbstractText>We evaluated...
8,970
Role of KATP channels in repetitive induction of ventricular fibrillation.
Patients with sustained ventricular tachyarrhythmias are at high risk for sudden cardiac death. The mechanisms leading to multiple temporally related episodes of ventricular fibrillation (VF) are not yet fully elucidated, and treatment options are limited. We investigated whether K(ATP)-channels could be involved in tr...
8,971
Clinical manifestations of arrhythmogenic right ventricular cardiomyopathy in Korean patients.
The clinical manifestations of the Korean patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) are not well known.</AbstractText>The clinical data of Korean patients who met the Task Force Criteria for ARVC were analyzed.</AbstractText>Thirty-seven patients (41.2+/-14.8 years old, 19 males) were diagnos...
8,972
Acute myocardial infarction during pregnancy successfully treated with primary percutaneous coronary intervention.
We report a case of a 40 year old pregnant woman who presented with an acute myocardial infarction (AMI) complicated by ventricular fibrillation. She underwent successful primary percutaneous coronary intervention (PCI). With a tendency towards increased maternal age in developed countries, AMI during pregnancy may bec...
8,973
Percutaneous mitral balloon valvotomy.
Percutaneous mitral balloon valvotomy (PMBV) was introduced in 1984 by Inoue who developed the procedure as a logical extension of surgical closed commissurotomy. Since then, PMBV has emerged as the treatment of choice for severe pliable rheumatic mitral stenosis (MS). With increasing experience and better selection of...
8,974
A case of short-coupled variant of torsade de pointes characterized by spatial heterogeneity of action potential duration and its restitution kinetics.
A 21-year-old male experienced frequent episodes of polymorphic ventricular tachycardia (PVT) initiated by a closely coupled premature ventricular complex (PVC) in the absence of QT prolongation and structural heart disease. Programmed stimulation at right ventricular apex (RVA), but not at the outflow tract (RVOT), pr...
8,975
Factors affecting error in integration of electroanatomic mapping with CT and MR imaging during catheter ablation of atrial fibrillation.
Integration of 3-D electroanatomic mapping with Computed Tomographic (CT) and Magnetic Resonance (MR) imaging is gaining acceptance to facilitate catheter ablation of atrial fibrillation. This is critically dependent on accurate integration of electroanatomic maps with CT or MR images. We sought to examine the effect o...
8,976
Long-term follow-up of primary prophylactic implantable cardioverter-defibrillator therapy in Brugada syndrome.
To analyse the follow-up data of implantable cardioverter-defibrillator (ICD) therapy in Brugada syndrome (BS).</AbstractText>We conducted a retrospective, single centre study of 47 patients (mean age: 44.5 +/- 15 years) with BS, who underwent primary prophylactic ICD implantation. All patients had baseline spontaneous...
8,977
Variability in survival after in-hospital cardiac arrest depending on the hospital level of care.
Survival after in-hospital cardiac arrest (IHCA) differs considerably between hospitals. This study tries to determine whether this difference is due to patient selection because of the hospital level of care or to effective resuscitation management.</AbstractText>Prospectively collected data on management of in-hospit...
8,978
Improving outcomes in chronic heart failure.
The publication of trials of angiotensin receptor blockers (ARBs) in recent years has led to the need to update the European Society of Cardiology guidelines for the management of chronic heart failure. Of primary importance among these studies were the three trials of the CHARM program comparing candesartan and placeb...
8,979
Pathophysiological mechanism of cardiac arrhythmias as a key for optimal nonpharmacological treatment.
Pathological automatism and triggered activity had focal origin. Thus, the treatment has to be aimed at ablation of the arrhythmogenic region. Some arrhythmogenic places can be precisely characterized by analysis of ECG patterns. Among them are foci located close to the pulmonary veins, sinus node, ventricular outflow ...
8,980
Intimal cardiac sarcoma in a pregnant woman.
A 29-year-old female patient in the 28th week of pregnancy was diagnosed with a cardiac tumor. We performed tumor excision and mitral valve replacement, and her baby was born successfully with cesarean section on the 9th day after cardiac surgery. After this event, 8 cycles of chemotherapy were administered. After 10 m...
8,981
Impact of anxiety and perceived control on in-hospital complications after acute myocardial infarction.
We tested the hypothesis that perception of control moderates any relationship between anxiety and in-hospital complications (i.e., recurrent ischemia, reinfarction, sustained ventricular tachycardia or fibrillation, and cardiac death) in patients with acute myocardial infarction (AMI).</AbstractText>Anxiety is common ...
8,982
[Cardioversion of amiodarone-insensitive atrial fibrillation by bepridil in heart failure: two case reports].
Two patients presented with atrial fibrillation which was refractory to amiodarone but successfully treated with bepridil. A 76-year-old man with ischemic cardiomyopathy, non-sustained ventricular tachycardia (NSVT) and atrial fibrillation received amiodarone for NSVT, which disappeared but atrial fibrillation was sust...
8,983
Fulminant myocarditis survivor after 56 hours of non-responsive cardiac arrest successfully returned to normal life by cardiac resynchronization therapy: a case report.
A 20-year-old female survived fulminant myocarditis with 56 hr of non-responsive cardiac arrest and was able to resume a normal life with cardiac resynchronization therapy(CRT). On admission, she had developed cardiogenic shock refractory to pharmacological intervention. Percutaneous cardiopulmonary support was initiat...
8,984
Effect of autonomic nervous system dysfunction on sudden death in ischemic patients with anginal syndrome died during electrocardiographic monitoring in Intensive Care Unit.
The aim of this study was to investigate the role of sympathovagal imbalance in patients with ''ischemic'' sudden death (arrhythmic death preceded by ST segment shift). Although heart rate variability is a powerful tool for risk stratification after myocardial infarction, the mechanism precipitating sudden death is poo...
8,985
Familial clustering of lone atrial fibrillation in patients with saddleback-type ST-segment elevation in right precordial leads.
We recently identified a large family with a high prevalence of lone atrial fibrillation (AF) and saddleback-type ST-segment elevation in leads V(1-3), without a history of ventricular arrhythmias or syncope. On the basis of this finding, we studied whether there is a relationship between saddleback ST-elevation and lo...
8,986
Pauses in chest compression and inappropriate shocks: a comparison of manual and semi-automatic defibrillation attempts.
Semi-automatic defibrillation requires pauses in chest compressions during ECG analysis and charging, and prolonged pre-shock compression pauses reduce the chance of a return of spontaneous circulation (ROSC). We hypothesised that pauses are shorter for manual defibrillation by trained rescuers, but with an increased n...
8,987
Cardiac magnetic resonance imaging investigation of sustained ventricular fibrillation in a swine model--with a focus on the electrical phase.
We sought to develop a method to evaluate the rapidly changing cardiac dimensions during sustained ventricular fibrillation (VF). We also present details of our CPR research imaging program to facilitate this avenue of clinically important research.</AbstractText>The changes in cardiac dimensions occurring during the i...
8,988
Treatment and outcome in post-resuscitation care after out-of-hospital cardiac arrest when a modern therapeutic approach was introduced.
The outcome among patients who are hospitalised alive after out-of-hospital cardiac arrest is still relatively poor. At present, there are no clear guidelines specifying how they should be treated. The aim of this survey was to describe the outcome for initial survivors of out-of-hospital cardiac arrest when a more agg...
8,989
The susceptibility of ventricular arrhythmia to aconitine in conscious Lyon hypertensive rats.
The present work was designed to investigate the relationship between hemodynamic parameters and the susceptibility of ventricular arrhythmia to aconitine in conscious Lyon hypertensive rats (LH).</AbstractText>Male LH and Lyon low blood pressure rats (LL) were used. After the determination of baroreflex sensitivity (B...
8,990
The resting electrocardiogram in the management of patients with congestive heart failure: established applications and new insights.
The resting electrocardiogram (ECG) furnishes essential information for the diagnosis, management, and prognostic evaluation of patients with congestive heart failure (CHF). Almost any ECG diagnostic entity may turn out to be useful in the care of patients with CHF, revealing the non-specificity of the ECG in CHF. Neve...
8,991
Influence of reciprocating tachycardia on the development of atrial fibrillation in patients with preexcitation syndrome.
We sought to evaluate the influence of atrio-ventricular reentrant tachycardia (AVRT) on atrial pressures during tachycardia and the presence of atrial fibrillation (AF) in patients with preexcitation syndrome.</AbstractText>The study population consisted of 88 patients (37 females, mean age 37.3 years) with left-sided...
8,992
Symptomatic hypoglycemia in a patient with chronic hemodialysis.
We describe the case of a 71-years-old man in chronic hospital hemodialysis who was admitted to the hospital because of symptomatic hypoglycemia. We discovered that this was due to a documented intoxication with cibenzoline, an antiarrhythmic drug, used to treat (supra-)ventricular tachyarrhythmia. In addition we made ...
8,993
Central venous pressure: an old lady in new clothes?
Invasive haemodynamic monitoring plays a pivotal role in critically ill patients. In this respect, central venous pressure is one of the most often used parameters. This review aims to provide an overview of the use of central venous pressure monitoring, the advantages and shortcomings, besides pitfalls. The integratio...
8,994
Signs in vector-electrocardiography (VECG) predicting the fibrillatory propensity of iodixanol and mannitol solutions after injection into the left coronary artery of pigs.
To find signs in vector-electrocardiography (VECG) predicting the ventricular fibrillatory propensity (VF-PROP) of iodixanol and mannitol solutions after injection into the left coronary artery (LCA) of pigs.</AbstractText>Five plasma-isotonic solutions perfused LCA: Iod 320 + Na/Ca (iodixanol 320 mg I/mL, 19 mM NaCl, ...
8,995
Atrial fibrillation and revascularization procedures: clinical and prognostic significance. Incidence, predictors, treatment, and long-term outcome.
Atrial fibrillation is the most common disorder of cardiac rhythm. In spite of simplicity of diagnosis, patients with atrial fibrillation are difficult to treat. In the recent years with the description of the phenomenon called remodelling, it has been possible to better define the principal mechanisms responsible for ...
8,996
Left atrial anatomy and function after conversion from atrial fibrillation in hypertrophic hearts.
The aim of the study was to evaluate the influence of left ventricular (LV) hypertrophy on left atrial (LA) electrical and mechanical function after cardioversion atrial fibrillation (A-Fib) of brief duration. Study group A included 100 patients with a first diagnosis of hypertension who had a moderate LV hypertrophy. ...
8,997
Contrasting gene expression profiles in two canine models of atrial fibrillation.
Gene-expression changes in atrial fibrillation patients reflect both underlying heart-disease substrates and changes because of atrial fibrillation-induced atrial-tachycardia remodeling. These are difficult to separate in clinical investigations. This study assessed time-dependent mRNA expression-changes in canine mode...
8,998
[Acute cardiogenic shock with inferior myocardial infarction associated with an abnormal origin of the coronary arteries].
A 45-year-old previously healthy man was admitted as an emergency having suddenly gone into cardiogenic shock. He had not been on any medications. The only known risk factor for cardiovascular disease was heavy smoking.</AbstractText>The patient was awake and responsive on admission but showed early signs of cardiogeni...
8,999
Tea consumption and infarct-related ventricular arrhythmias: the determinants of myocardial infarction onset study.
Tea consumption is associated with lower post-infarct mortality among patients with acute myocardial infarction. We previously found preliminary evidence that tea consumption may also be associated with lower risk of infarct-related ventricular arrhythmias.</AbstractText>Between 1989 and 1996, 3882 subjects with AMI we...