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8,700
Lovastatin specifically prevents focal ischemic ventricular tachycardia due to triggered activity.
Use of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor has been associated with reduced implantable defibrillator shocks in several multicenter trials, suggesting an antiarrhythmic effect.</AbstractText>The purpose of this study was to determine if lovastatin had an antiarrhythmic effect in a canine...
8,701
Human KCNQ1 S140G mutation is associated with atrioventricular blocks.
We recently reported that an S140G mutation in human KCNQ1, an alpha subunit of potassium channels, was involved in the pathogenesis of familial atrial fibrillation (AF), but it is not clear whether the mutation is associated with other cardiac arrhythmias.</AbstractText>The purpose of this study was to further explore...
8,702
Use of intracardiac echocardiography to guide implantation of a left atrial appendage occlusion device (PLAATO).
Over 90% of thrombi in atrial fibrillation (AF) originate from the left atrial appendage (LAA). Patients with contraindications to anticoagulation are potential candidates for LAA occlusion using the Percutaneous Left Atrial Appendage Transcatheter Occlusion system (PLAATO, ev3 Inc., Plymouth, MN). Transesophageal echo...
8,703
Defibrillator availability on rotor-wing critical care transports.
Defibrillation is a time-critical and life-saving intervention for patients in ventricular fibrillation or ventricular tachycardia. The preparation of rotor-wing critical care transport teams to manage such arrhythmias out of the transport vehicle is unclear.</AbstractText>A mail and telephone survey of 230 rotor-wing ...
8,704
Shock outcome is related to prior rhythm and duration of ventricular fibrillation.
Several different ventricular fibrillation (VF) analysis features based on ECG have been reported for shock outcome prediction. In this study we investigated the influence of the time from VF onset to shock delivery (VF duration) and the rhythm before onset of VF, on the probability of return of spontaneous circulation...
8,705
Nitric oxide synthase isoform inhibition before whole body ischemia reperfusion in pigs: vital or protective?
Nitric oxide (NO) is a critical regulator of vascular tone, and signal transduction. NO is produced via three unique synthases (NOS); endothelial (eNOS), and neuronal (nNOS) are both constitutively expressed and inducible (iNOS) produced primarily after stimulation. NO has been implicated during and after ischemia repe...
8,706
Direct effects of apelin on cardiomyocyte contractility and electrophysiology.
Apelin, the ligand for the angiotensin receptor like-1, has been implicated in the pathogenesis of atrial fibrillation and heart failure. However, it is unknown if apelin has direct effects on cardiomyocyte contractility and electrophysiology. APJ-like immunoreactivity was localized to T-tubules and intercalated disc a...
8,707
Ischaemic stroke, factor V Leiden heterozygosity and left atrial thrombosis in sinus rhythm: a case report.
We describe a 63-year-old man in sinus rhythm (SR) with an ischaemic stroke involving basal ganglia region on the right side. The patient was known to be heterozygous for factor V Leiden (FVL) mutation. On diagnostic work-up, no arterial sources of embolism were found. Transoesophageal echocardiography evidenced a left...
8,708
Risk factors for prolonged intensive care treatment following atrial septal defect closure in adults.
Today, percutaneous or surgical closure of atrial septal defects (ASD) in adults are considered effective and safe treatments. However, some cases of severe left ventricular dysfunction after ASD closure were observed. This study aims at identifying predictors for prolonged intensive care unit stay, and postoperative i...
8,709
Use of conventional dual chamber pacemakers with custom lead adapters to induce atrial fibrillation or heart failure in dogs.
The purpose of this article is to show how custom "Y"-lead adapters and standard dual-chamber pacemakers can be used to produce pacing paradigms that will lead to stable experimental models of heart failure and atrial fibrillation.</AbstractText>With two custom lead adapters we used both ports of two dual-chamber clini...
8,710
Idiopathic ventricular fibrillation successfully terminated by radiofrequency ablation of the distal Purkinje fibers.
A 21-year-old woman was admitted for evaluation of recurrent episodes of syncope. She had several spontaneous and abrupt loss of consciousness episodes while at the emergency department, caused by sustained and nonsustained ventricular fibrillation episodes. Each episode was initiated by a certain premature ventricular...
8,711
The dilemma of ICD implant testing.
Ventricular fibrillation (VF) has been induced at implantable cardioverter defibrillator (ICD) implant to ensure reliable sensing, detection, and defibrillation. Despite its risks, the value was self-evident for early ICDs: failure of defibrillation was common, recipients had a high risk of ventricular tachycardia (VT)...
8,712
Incidence and initial characteristics of pilsicainide-induced ventricular arrhythmias in patients with Brugada syndrome.
In patients with Brugada syndrome, class I antiarrhythmic drugs can trigger ventricular arrhythmias (VA). The incidence and initial characteristics of VA that developed after pilsicainide was examined in 28 patients with Brugada-type electrocardiographic (ECG) abnormalities and with a positive response in the pilsicain...
8,713
Achieving sufficient safety margins with fixed duration waveforms and the use of multiple time constants.
There are several options to achieve a sufficient safety margin in a patient with a high defibrillation threshold (DFT), with varying and typically modest success. Programming fixed (millisecond) durations of both phases of a biphasic waveform in an implantable cardioverter defibrillator (ICD) has demonstrated utility....
8,714
[A case of right ventricular ischemia mimicking acute myocardial infarction during coronary angioplasty on the right coronary artery].
A 55-year-old man was admitted to our department with a diagnosis of acute inferior myocardial infarction; 1 week later he underwent percutaneous transluminal coronary angioplasty on the proximal right coronary artery; during this procedure, the patient experienced chest pain and his electrocardiogram showed ST-segment...
8,715
Prognosis of patient with cardiopulmonary arrest transported to Kyushu University Hospital.
Three hundreds and sixty six patients with out-of-hospital cardiopulmonary arrest, transported to the Kyushu University Hospital from 2000 to 2006, were examined using the Utstein style in witnessed cardiogenic cardiopulmonary arrest patients. Also, we examined the influence on prognosis due to the difference in the tr...
8,716
Noninvasive assessment of left atrial function by strain rate imaging in patients with hypertension: a possible beneficial effect of renin-angiotensin system inhibition on left atrial function.
Renin-angiotensin system (RAS) inhibitors are likely to reduce the development of atrial fibrillation by preventing atrial fibrosis. Strain rate (SR) imaging is a novel echocardiographic technique to quantify left atrial (LA) function. However, it has not been determined whether SR imaging is applicable for detection o...
8,717
Gamma-irradiated ceruloplasmin affords antifibrillatory protection against ischemia/reperfusion damage in the isolated rat heart.
Ceruloplasmin (CP), an important serum antioxidant, was previously found to reduce the incidence of ventricular fibrillation (VF) induced by ischemia and reperfusion in isolated rat hearts. The present study investigated whether CP sterilized by gamma-irradiation maintains its antiarrhythmic capacity and in vitro antio...
8,718
Postresuscitation accelerated idioventricular rhythm: a potential prognostic factor for out-of-hospital cardiac arrest survivors.
Data are lacking on the relationship between postresuscitation ECG and outcome in out-of-hospital cardiac arrest (OHCA). We examined the prognostic information that postresuscitation ECG rhythm can provide for predicting outcome in OHCA survivors.</AbstractText>The retrospective observational study enrolled 56 successf...
8,719
Utility of intracardiac echocardiography in left heart ablation for tachyarrhythmias.
Catheter-based radiofrequency ablation in the left heart can provide effective therapy for tachyarrhythmias. The recent development of the real time intracardiac echocardiography (ICE) with 2D and Doppler color flow imaging can facilitate left heart ablation procedures. This report reviews the use of ICE during radiofr...
8,720
Usefulness of bedside tissue Doppler echocardiography and B-type natriuretic peptide (BNP) in differentiating congestive heart failure from noncardiac cause of acute dyspnea in elderly patients with a normal left ventricular ejection fraction and permanent, nonvalvular atrial fibrillation: insights from a prospective, ...
The incremental role of bedside tissue Doppler echocardiography and B-type natriuretic peptide (BNP) over the clinical judgment has been recently reported in the emergency diagnosis of congestive heart failure with a normal left ventricular ejection fraction (HFNEF). However, how well does this diagnostic strategy be a...
8,721
Effects of an impedance threshold device on hemodynamics and restoration of spontaneous circulation in prolonged porcine ventricular fibrillation.
An impedance threshold device (ITD) has been designed to enhance circulation during CPR by creating a negative intrathoracic pressure during the relaxation phase of chest compression.</AbstractText>We sought to determine the effects of the ITD on coronary perfusion pressure (CPP), return of spontaneous circulation (ROS...
8,722
Differentiation between the two types of amiodarone-associated thyrotoxicosis using duplex and amplitude Doppler sonography.
To evaluate the usefulness of Doppler parameters in the differentiation between the two types of amiodarone-associated thyrotoxicosis (AAT).</AbstractText>One hundred thirty-seven individuals were selected at our institution. They were divided into four groups: 84 normal subjects (N), 30 euthyroids taking amiodarone (A...
8,723
Interventional electrophysiology and cardiac resynchronization therapy: delivering electrical therapies for heart failure.
Implantable devices have become a readily available option for patients with heart failure. Not only do these patients develop bradycardia and ventricular tachycardia, but their ventricular dysfunction can often improve with cardiac resynchronization therapy. However, this is a complex and rapidly developing clinical s...
8,724
Long-term survival after successful inhospital cardiac arrest resuscitation.
Little is known about long-term outcomes of patients who survive inhospital cardiac arrest.</AbstractText>We examined long-term survival after inhospital cardiac arrest and whether procedural changes that improved survival to discharge impacted long-term survival. Consecutive inhospital arrests in the Atlanta Veterans ...
8,725
Outcome after out-of-hospital cardiac arrest in a physician-staffed emergency medical system according to the Utstein style.
Despite a large amount of data assessing outcomes of out-of-hospital cardiac arrests (OHCAs), little information is available about physician-staffed emergency medical service (EMS) systems. The aim of our study was to investigate the impact of a physician on the outcome of patients after OHCA.</AbstractText>This is a ...
8,726
The relationship between shocks and survival in out-of-hospital cardiac arrest patients initially found in PEA or asystole.
To describe survival rates from out-of-hospital cardiac arrest for patients who present with pulseless electrical activity or asystole according to whether they remained in a non-shockable rhythm or converted to ventricular fibrillation and were shocked appropriately.</AbstractText>Observational analysis of a cardiac a...
8,727
Ventricular fibrillation induced by transoesophageal cardiac pacing: a new model of cardiac arrest in rats.
To investigate whether transoesophageal cardiac pacing can induce ventricular fibrillation (VF) and how long the cardiac pacing has to be sustained to prevent the reversion of the VF induced.</AbstractText>A pacing electrode was inserted orally into the oesophagus and high-frequency ventricular pacing was performed so ...
8,728
[Chronic heart failure treatment in the year 2006].
Heart failure (HF) has a high incidence, near 2% of the population suffered this process, that increases with the age, affecting between 15-20 % of the population elder than 70 years. In the last 20 years the knowledge in pathophysiological mechanisms has improved, mainly, the role of neurohormonal response in the deve...
8,729
Left atrial remodelling contributes to the progression of asymptomatic left ventricular systolic dysfunction to chronic symptomatic heart failure.
Systolic heart failure (HF) is a progressive disorder that often begins with asymptomatic left ventricular (LV) systolic dysfunction and culminates in symptoms from fluid overload and poor end-organ perfusion. The progression to symptomatic HF is accompanied by marked activation of neurohormonal and cytokine systems, a...
8,730
Resynchronization therapy in the context of atrial fibrillation: benefits and limitations.
Atrial fibrillation (AF) and heart failure often coexist and are believed to directly predispose to each other. Cardiac resynchronization does not prevent or increase the induction of AF. However, new onset of AF does not seem to diminish the beneficial effects of CRT on symptoms, cardiac function and, more importantly...
8,731
Use of intravenous magnesium to treat acute onset atrial fibrillation: a meta-analysis.
To assess the effects of intravenous magnesium on converting acute onset atrial fibrillation to sinus rhythm, reducing ventricular response and risk of bradycardia.</AbstractText>Randomised controlled trials evaluating intravenous magnesium to treat acute onset atrial fibrillation from MEDLINE (1966 to 2006), EMBASE (1...
8,732
Mechanisms, prediction and treatment of ventricular tachyarrhythmias occurring late after myocardial infarction.
Studies from the 1980s, refined in the intervening years, have examined the milieu for ventricular tachycardia (VT) and ventricular fibrillation (VF) occurring late after acute myocardial infarction (AMI). The arrhythmogenic substrate appears to be patchy areas of fibrous tissue interdigitating with viable bundles of m...
8,733
Spironolactone reduced arrhythmia and maintained magnesium homeostasis in patients with congestive heart failure.
Patients with congestive heart failure (CHF) often have increased aldosterone activity that leads to hypomagnesemia. Hypomagnesemia can induce arrhythmias, an important cause of death in patients with CHF. We determined whether the aldosterone receptor antagonist spironolactone improved magnesium homeostasis and reduce...
8,734
Accuracy of electrocardiogram interpretation improves with emergency medicine training.
To assess whether electrocardiogram (ECG) interpretation accuracy improves with advancing years of emergency medicine training.</AbstractText>A prospective cross-sectional double-blinded study of emergency medicine trainees attending teaching sessions in ACEM accredited Victorian hospitals. Subjects completed a survey ...
8,735
[Heterotaxia syndrome without congenital cardiac defects in dilated cardiomyopathy].
HISTORY AND OUTPATIENT INVESTIGATION: A 61-year-old woman presented with a six-month history of chest pain and shortness of breath on normal activity. The past medical history included hypertension treated with ACE inhibitors. While still an outpatient a diagnosis was made of cardiomyopathy with left atrial and ventric...
8,736
Assessment, significance and mechanism of ventricular electrical instability after myocardial infarction.
The mechanism of reentrant tachycardia was established nearly a century ago, but the relationships between myocardial infarction and predisposition to sudden death were not unravelled until much later. In the latter half of the twentieth century many studies sought to ascertain what variables were predictive of death f...
8,737
[Atrial electrical, contractile and structural remodeling induced by short-term atrial tachycardia in a canine model].
To evaluate atrial remodeling induced by short term pacing in a canine model.</AbstractText>Transvenous lead was inserted into the right atrial appendage of anesthetized mongrel dogs and paced for 5 hours at 450 bpm (n=12). Effective refractory period (ERP) and P-wave duration were measured before and post pacing and l...
8,738
Continuous arteriovenous haemofiltration to regulate hyperkalaemia during renal transplantation: a case report.
Progressive hyperkalaemia is common in end stage renal disease patients waiting for renal transplantation. Ventricular tachycardia and ventricular fibrillation due to hyperkalaemia are life-threatening complications in these patients. In live and related renal transplant, after induction and anaesthesia, ventricular fi...
8,739
Prognostic value of the computerized ECG in Hispanics.
The prevalence and prognostic values of electrocardiogram (ECG) abnormalities in Hispanics have not been compared to other ethnicities in a large population. Despite a worse cardiovascular risk profile, the prevalence of cardiovascular disease is lower in Hispanics compared to non-Hispanics.</AbstractText>We hypothesiz...
8,740
Clinical characteristics and outcomes of hypertrophic cardiomyopathy in Taiwan--a tertiary center experience.
Most information concerning hypertrophic cardiomyopathy has been derived from western countries and Japan.</AbstractText>Patients with hypertrophic cardiomyopathy in Taiwan may have a distinct morphology and clinical picture.</AbstractText>Information from 163 consecutive patients with hypertrophic cardiomyopathy at a ...
8,741
Intravenous magnesium for acute myocardial infarction.
Mortality and morbidity from acute myocardial infarction (AMI) remain high. Intravenous magnesium started early after the onset of AMI is thought to be a promising adjuvant treatment. Conflicting results from earlier trials and meta-analyses warrant a systematic review of available evidence.</AbstractText>To examine th...
8,742
Out of the guidelines: should an intracardiac defibrillator be implanted in patients with recurrent early ventricular fibrillation due to recurrent acute myocardial infarction?
We report the case of a patient admitted to the hospital on two different occasions, separated by a time interval of 12 years, with the same clinical picture: acute anterior myocardial infarction complicated by early ventricular fibrillation. The patient was successfully resuscitated because, in both circumstances, he ...
8,743
Sudden death in a patient with lamin A/C gene mutation and near normal left ventricular systolic function.
Mutations in the lamin A/C gene seem to be important aetiological factors in familial DCM. Heart disease caused by lamin A/C gene mutations is characterised by conduction system disorders with the need for permanent pacemaker implantations, atrial fibrillation, severe heart failure, and increased risk for sudden cardia...
8,744
Cytokines, interstitial collagen and ventricular remodelling in dilated cardiomyopathy.
Dilated cardiomyopathy (DCM) is associated with myocardial fibrosis, and proinflammatory cytokines may play a role in this.</AbstractText>N-terminal type I and III procollagen propeptides (PINP, PIIINP) and cross-linked telopeptide of type I collagen (ICTP) were measured from serum samples of 73 patients with DCM and 5...
8,745
Ventricular fibrillation after a hymenoptera sting.
A 54-year-old male, who had presented 2 ventricular fibrillation (VF) episodes with post-anoxic coma and later a return to consciousness and to a sinusal rhythm after defibrillation, have been placed a ventricular intracavitary stimulator (AICD). Since all the tests including the coronarygraphy have been found normal, ...
8,746
Reduction of ventricular tachyarrhythmia by treatment of atrial fibrillation in ICD patients with dual-chamber implantable cardioverter/defibrillators capable of atrial therapy delivery: the REVERT-AF Study.
The purpose of this prospective, randomized, multicentre study was to investigate whether the incidence of ventricular tachyarrhythmia can be reduced in standard implantable cardioverter/defibrillator (ICD) patients by implanting a dual-chamber ICD capable of atrial therapy delivery.</AbstractText>A Jewel AF or GEM III...
8,747
In vitro and in vivo effects of the atrial selective antiarrhythmic compound AVE1231.
The novel compound AVE1231 was investigated in order to elucidate its potential against atrial fibrillation. In CHO cells, the current generated by hKv1.5 or hKv4.3 + KChIP2.2b channels was blocked with IC50 values of 3.6 microM and 5.9 microM, respectively. In pig left atrial myocytes, a voltage-dependent outward curr...
8,748
Ventricular arrhythmias during left ventricular assist device support.
Left ventricular assist devices (LVADs) have been used effectively as a "bridge" to cardiac transplantation and as destination therapy in patients with advanced heart failure. Ventricular arrhythmias (VAs) have been reported to occur in LVAD-supported patients, although their incidence, risk factors, and clinical signi...
8,749
Ventricular tachycardia in non-compaction of left ventricle: is this a frequent complication?
Isolated left ventricular non-compaction is the result of incomplete myocardial morphogenesis, leading to persistence of the embryonic myocardium. The condition is recognized by an excessively prominent trabecular meshwork and deep intertrabecular recesses of the left ventricle. Whether these intertrabecular recesses a...
8,750
Reverse electrical remodeling of the atria post cardioversion in patients who remain in sinus rhythm assessed by signal averaging of the P-wave.
This study was designed to determine whether the signal-averaged electrocardiogram of the P-wave (SAPW) is an independent predictor of recurrence of atrial fibrillation (AF) post cardioversion (CV), and to assess atrial remodeling using SAPW.</AbstractText>There are limited electrophysiologic data to predict the recurr...
8,751
[Ablation of a catecholaminergic polymorphic VT and VF originating from Purkinje fibers--a case report].
We describe a case of a 25-year-old woman suffering from recurrent adrenergic polymorphic ventricular tachycardia (PVT). As a 14-year-old the patient suffered from recurrent episodes of syncope during exercise or emotion. On Holter monitoring unsustained runs of PVT were observed. The patient survived SCD (VF) which oc...
8,752
Pulmonary thromboembolism in 102 consecutive patients with chronic atrial fibrillation. Diagnostic value of echocardiography.
Little is known about the incidence and diagnosis of pulmonary thromboembolism (PE) in patients with chronic permanent atrial fibrillation (CAF). Also it has not been established if echocardiography, a diagnostic tool useful in clinical evaluation of both diseases, is of value in diagnosis of PE in CAF patients.</Abstr...
8,753
Contemporary catheter ablation of arrhythmias in geriatric patients: patient characteristics, distribution of arrhythmias, and outcome.
Catheter ablation is a treatment of first choice for many arrhythmias. Data in geriatric patients are still limited, mostly focusing on single arrhythmia types. The aim of the study was to investigate characteristics of contemporary ablation therapy in the very elderly, focusing on patient characteristics, arrhythmia s...
8,754
Effects of garlic on defibrillation efficacy.<Pagination><StartPage>143</StartPage><EndPage>144</EndPage><MedlinePgn>143-4</MedlinePgn></Pagination><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Sungnoon</LastName><ForeName>Rattapong</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Shinl...
The principles of Fontan conversion with arrhythmia surgery are to restore the cardiac anatomy by converting the original atriopulmonary connection to a total cavopulmonary artery extracardiac connection and treat the underlying atrial arrhythmias. Successful outcomes of this procedure are dependent on a thorough under...
8,755
The incidence and significance of emesis associated with out-of-hospital cardiac arrest.
Studies have suggested that emesis may occur in up to a third of cardiac arrest patients. The goal of this investigation was to characterize the frequency, timing, and outcome association of emesis in persons suffering out-of-hospital cardiac arrest in order to understand the role and care-implications of emesis better...
8,756
[Lethal streptococcal toxic shock syndrome in pediatrics. Presentation of 3 cases].
Three cases of children admitted to the Pediatric Intensive Medicine Unit in the months of February to March 2004 with the diagnosis of streptococcal toxic shock syndrome are presented. Two were under 2 years of age and the initial symptoms suggested viriasis. They evolved towards septic shock with early multiorganic f...
8,757
Minimally invasive cardiopulmonary bypass: does it really change the outcome?
Many innovative cardiopulmonary bypass (CPB) systems have recently been proposed by the industry. With few differences, they all share a philosophy based on priming volume reduction, closed circuit with separation of the surgical field suction, centrifugal pump, and biocompatible circuit and oxygenator. These minimally...
8,758
[Familial short QT syndrome].
Short QT syndrome is a newly described cardiologic entity which associates a short OT interval (QT and QTc &lt; or = 300 ms) on the surface ECG to a high risk of syncope or sudden death due to malignant ventricular arrhythmia. This extremely rare syndrome affects mainly young adults or infants and has a wide clinical e...
8,759
P wave dispersion in patients with rheumatoid arthritis: its relation with clinical and echocardiographic parameters.
P wave dispersion (PWD) is a sign for the prediction of atrial fibrillation (AF). The aim of this study was to assess P wave dispersion and its relation with clinical and echocardiographic parameters in patients with rheumatoid arthritis (RA). Thirty RA patients (mean age 49 +/- 10 years) and 27 healthy controls (mean ...
8,760
Limiting sarcolemmal Na+ entry during resuscitation from ventricular fibrillation prevents excess mitochondrial Ca2+ accumulation and attenuates myocardial injury.
intracellular Na+ accumulation during ischemia and reperfusion leads to cytosolic Ca2+ overload through reverse-mode operation of the sarcolemmal Na+ -Ca2+ exchanger. Cytosolic Ca2+ accumulation promotes mitochondrial Ca2+ (Ca2+ m) overload, leading to mitochondrial injury. We investigated whether limiting sarcolemmal ...
8,761
How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology.
Diastolic heart failure (DHF) currently accounts for more than 50% of all heart failure patients. DHF is also referred to as heart failure with normal left ventricular (LV) ejection fraction (HFNEF) to indicate that HFNEF could be a precursor of heart failure with reduced LVEF. Because of improved cardiac imaging and b...
8,762
Implantable cardioverter-defibrillator shocks increase T-wave alternans.
While implantable defibrillator shocks save lives, shock can lead to ventricular arrhythmias. However, the mechanism of shock-related proarrhythmia remains unclear. We evaluated the impact of ICD shock on repolarization instability, a factor associated with ventricular arrhythmogenesis.</AbstractText>Sixty-five patient...
8,763
Estimation of microinhomogeneity of conduction impairment by wavelet analysis during early phase of myocardial ischemia in pigs.
Ventricular fibrillation (VF) is most frequent in the very early phase in acute coronary occlusion, and is triggered by the re-entrant mechanism in this phase. An inhomogeneous conduction in the ischemic myocardium would be substrates for re-entry. The aim of this study was to examine the relationship between the sever...
8,764
[Prevention of ischemic stroke in middle aged patients with atrial fibrillation. Effect of sinus rhythm maintenance, aspirin, warfarin, and simvastatin].
Patients (n=263, age 49-64 years) with persistent nonvalvular atrial fibrillation were subjected to controlled treatment aimed at restoration and maintenance of sinus rhythm (n=134) or slowing of rate of ventricular contractions. Efficacy of complementary use of combination of simvastatin with aspirin, warfarin and asp...
8,765
[Clinical features of thyrotoxic heart disease: analysis of 75 cases].
To investigate the clinical features of thyrotoxic heart disease.</AbstractText>The clinical data of 75 patients with thyrotoxic heart disease, 30 males and 45 females, aged 54.3 +/- 14.4 (17 approximately 84, with the course from 1 month to 30 years, were analyzed retrospectively.</AbstractText>Forty-seven of the 75 p...
8,766
Bivalirudin anticoagulation for cardiopulmonary bypass: an unusual case.
The standard agent used for systemic anticoagulation during cardiopulmonary bypass is heparin. Alternative methods of anticoagulation are required for patients with heparin hypersensitivity. We present the case of a patient with heparin hypersensitivity who was anticoagulated with bivalirudin during cardiopulmonary byp...
8,767
Atrial fibrillation with left bundle branch block and intermittent right axis deviation during acute myocardial infarction.
Rarely the ECG shows an LBBB with changing QRS morphology and changing axis deviation. The intermittent positive aspect of the neglected lead aVR indicates an intermittent right axis deviation in the presence of complete LBBB. An additional left posterior fascicular block accompanying predivisional LBBB is the possible...
8,768
Respiratory controversies in the critical care setting. Should all patients be treated with hypothermia following cardiac arrest?
Cardiac arrest is a common and lethal medical problem; each year more than half a million people in the United States and Canada suffer cardiac arrest treated by emergency medical personnel or in-hospital providers. Of those who survive to hospital admission or suffer in-hospital arrest, 40-60% die prior to discharge. ...
8,769
Is there an anatomical substrate for idiopathic paroxysmal atrial fibrillation? A case-control echocardiographic study.
Idiopathic paroxysmal atrial fibrillation (AF) occurs in patients with apparently normal heart. Its mechanisms may be complex and are poorly understood. The aim of the study was to evaluate whether patients with idiopathic AF have any structural abnormality that may explain the occurrence of AF.</AbstractText>A case-co...
8,770
Is all ventricular fibrillation the same? A comparison of ischemically induced with electrically induced ventricular fibrillation in a porcine cardiac arrest and resuscitation model.
The standard porcine cardiac arrest model uses electrical induction of ventricular fibrillation. Reported restoration of spontaneous circulation and survival rates in this model are as high as 90% for ventricular fibrillation durations of 7-10 mins, values substantially greater than rates in the clinical population (i....
8,771
Prognostic role of post-infarction C-reactive protein in patients undergoing implantation of cardioverter-defibrillators: design of the C-reactive protein Assessment after Myocardial Infarction to GUide Implantation of DEfibrillator (CAMI GUIDE) study.
Patients at risk of sudden cardiac death (SCD) after myocardial infarction (MI) can currently be offered effective means of prevention, such as implantable cardioverter-defibrillators (ICD). However, predictors of SCD able to identify those patients who are at higher risk are still lacking. Whether C-reactive protein (...
8,772
An unusual case of tricuspid lesion in congenital corrected transposition of the great arteries.
An unusual case of severe supravalvular stenosing ring of the left atrium associated with tricuspid valve dysplasia in an adult symptomatic patient affected by congenitally corrected transposition and unrestrictive ventricular septal defect is reported. The stenosis of the systemic atrioventricular valve possibly preve...
8,773
Turbulence control with local pacing and its implication in cardiac defibrillation.
In this review article, we describe turbulence control in excitable systems by using a local periodic pacing method. The controllability conditions of turbulence suppression and the mechanisms underlying these conditions are analyzed. The local pacing method is applied to control Winfree turbulence (WT) and defect turb...
8,774
Arrhythmogenesis in the heart: Multiscale modeling of the effects of defibrillation shocks and the role of electrophysiological heterogeneity.
The mechanisms of initiation of ventricular arrhythmias as well as those behind the complex spatiotemporal wave dynamics and its filament organization during ventricular fibrillation (VF) are the topic of intense research and debate. Mechanistic inquiry into the various mechanisms that lead to arrhythmia initiation and...
8,775
Negative filament tension in the Luo-Rudy model of cardiac tissue.
Scroll waves are vortices that occur in three-dimensional excitable media. Scroll waves have been observed in a variety of systems including cardiac tissue, where they are associated with cardiac arrhythmias. The disorganization of scroll waves into chaotic behavior is thought to be the mechanism of ventricular fibrill...
8,776
Mechanical aortic and mitral valve replacement in infants and children.
The aim of this study was to evaluate early and late outcomes after mechanical systemic heart valve replacement in pediatric patients.</AbstractText>Between October 1981 and December 2003, 32 children (mean age 7.2 +/- 5.4 years; 4 months - 15.9 years) underwent mechanical mitral (MVR, n = 17), aortic (AVR, n = 13) or ...
8,777
Clinical usefulness of electrophysiologic study (EPS)-guided risk stratification for life-threatening arrhythmia in patients with heart failure.
Ventricular tachyarrhythmia is one of the most important factors determining the prognosis of patients with heart failure and sudden death can be observed even during stable therapy controlling clinical heart failure. In this study, the usefulness of electrophysiologic study (EPS) for the prediction of a future arrhyth...
8,778
A successfully novel ICD implantation and medical treatment in a child with LQT syndrome and self-limiting ventricular fibrillation.
Beta-blocker is the first line drug therapy for congenital long QT syndrome. However, in some children this drug is ineffective. In a non-responder patient, Shimizu et al. used Mexiletine to suppress the ventricular arrhythmias, obtaining a good result. In the high risk patient, the ICD is necessary. However the implan...
8,779
Termination of atrial flutter by directed transesophageal atrial pacing during transesophageal echocardiography.
The purpose of this study was to evaluate termination of atrial flutter (AFL) by directed rapid transesophageal atrial pacing (TAP) with and without simultaneous transesophageal echocardiography (TEE) performed using a novel TEE tube electrode.</AbstractText><AbstractText Label="MATERIALS AND METHODS, AND RESULTS" NlmC...
8,780
[The best of arrhythmia in 2006].
Even though the year 2006 did not bring any major publication reporting therapeutic trials in the field of arrhythmia, it has been marked by the publication of important international guidelines on atrial fibrillation (AF), the treatment of ventricular arrhythmia and the prevention of sudden death, as well as studies o...
8,781
[The best of valvular heart disease in 2006].
In the field of valvular diseases, the year 2006 has been above all marked by the publication of new joint AHA/ACC guidelines. Besides, other publications included severe aortic stenosis, drug therapy in chronic aortic regurgitation, the indications for surgery in asymptomatic mitral regurgitation, as well as valve sur...
8,782
[Comparative study of the electrophysiological properties of class iii medicinals (cardiocyclide, nibentan, sotalol) and evaluation of their efficacy in atrial fibrillation produced by auricular and vagal stimulation].
The electrophysiological properties of cardiocyclide, nibentan and sotalol and their efficacy on a model of atrial fibrillation were compared in experiments in anaesthetized dogs. The electrophysiological parameters of drugs were investigated using the method of programmed electrical stimulation of myocardium on the ba...
8,783
[Heart failure and cardiomyopathies: a case report].
Isolated noncompaction of left ventricular myocardium is a rare congenital heart disease, characterized by an excessive prominence of trabecular meshwork, spaced out by deep intertrabecular recesses, consequent to the arrest of the normal myocardial embryogenesis. Although there are numerous descriptions, the pathophys...
8,784
Transient atrial fibrillation complicating acute inferior myocardial infarction: implications for future risk of ischemic stroke.
Atrial fibrillation (AF) that occurs as a frequent complication of myocardial infarction (MI) is associated with a poor clinical outcome. It nonetheless remains uncertain whether AF that occurs transiently during MI is associated with a subsequent increased risk of the development of AF and ischemic stroke.</AbstractTe...
8,785
Echocardiography-based spectrum of severe tricuspid regurgitation: the frequency of apparently idiopathic tricuspid regurgitation.
The cause of tricuspid valve (TV) regurgitation (TR) occasionally remains unclear. The objectives of our study were to define the causal spectrum of severe TR diagnosed by echocardiography at a tertiary medical center and to assess the relative frequency and determine the clinical and echocardiographic characteristics ...
8,786
Novel SCN5A mutation (Q55X) associated with age-dependent expression of Brugada syndrome presenting as neurally mediated syncope.
An association between Brugada syndrome and neurally mediated syncope has been described. Although mutations in SCN5A have been identified in Brugada syndrome, the genetic link between Brugada syndrome and neurally mediated syncope has not been determined.</AbstractText>The purpose of the study was to clinically and ge...
8,787
Impact of heart failure and left ventricular function on long-term survival--report of a community-based cohort study in Taiwan.
There is little community-based information on heart failure (HF) prognosis in ethnic Chinese populations, in whom there is a low prevalence of coronary heart disease.</AbstractText>To study the impact of HF and left ventricular function on long-term all-cause mortality.</AbstractText>This community-based prospective c...
8,788
Isolated atrial segment pacing: an alternative to His bundle pacing after atrioventricular junctional ablation.<Pagination><StartPage>1443</StartPage><EndPage>1449</EndPage><MedlinePgn>1443-9</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">This study was designed to investiga...
The cardioprotective properties of pharmacological and metabolic activators of mitoKATP are reviewed. Metabolic activators of the channels and data on their cardioprotective properties are discussed in the review. The authors adduce their own data concerning cardioprotective properties of mitoKATP channel metabolic act...
8,789
Pre-procedural predictors of atrial fibrillation recurrence after circumferential pulmonary vein ablation.
The success rate of circumferential pulmonary vein ablation (CPVA) to treat atrial fibrillation (AF) ranges from 60 to 90%, depending on the series. The objective of the study was to identify predictors of AF recurrence after a standardized CPVA procedure.</AbstractText>A series of 148 consecutive patients undergoing C...
8,790
On the role of ventricular conduction time in rate stabilization for atrial fibrillation.
Ventricular pacing (VP) could stabilize the ventricular rhythm in atrial fibrillation (AF). This study investigates the role of ventricular conduction time (VCT) in rate stabilization for AF.</AbstractText>A novel computer model was used to generate various patterns of RR intervals in AF. For each model configuration, ...
8,791
A case of recurrent transient left ventricular apical ballooning associated with atrial fibrillation.
We report the case of a post-menopausal female who presented two episodes of transient left ventricular apical ballooning associated with rapid atrial fibrillation within a four-month period. The clinical features of this phenomenon also known as Tako-tsubo mimic acute myocardial infarction and may be a form of catecho...
8,792
Arrhythmic complications of electrical cardioversion: relationship to shock energy.
Existing guidelines for electrical cardioversion (ECV) of atrial arrhythmias suggest starting at a low energy setting on the grounds that shocks of high energy might damage the myocardium or trigger more serious arrhythmias. We hypothesised that more powerful shocks would exceed the upper limit of vulnerability for ind...
8,793
Inappropriate shock delivery by implantable cardioverter defibrillator due to electrical interference with washing machine.
We report a patient with hypertrophic cardiomyopathy who received an inappropriate implantable cardioverter defibrillator shock due to electrical interference from a washing machine. This electrical interference was detected as an episode of ventricular fibrillation with delivery of shock without warning symptoms.
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Racial disparity and technology diffusion: the case of cardioverter defibrillator implants, 1996-2001.
Although implantable cardioverter defibrillator (ICD) therapy is widely endorsed for preventing sudden cardiac death (SCD), prior research documented a large black-white disparity in ICD therapy among the elderly. No studies have examined this disparity among nonelderly adults or over time as ICD therapy became widely ...
8,795
[Is potential equalization in hemodialysis treatments necessary?].
In some cases in haemodialysis blood access is established with a special type of central venous catheter (CVC), sometimes called a central dialysis catheter (CDC), instead of an AV fistula or graft. This central venous catheter tip is placed very close to the heart, increasing the probability of a leakage of electrica...
8,796
The TCM stage-oriented treatment for chronic cardiac insufficiency.
Generally, heart failure at the stable stage can be treated mainly with TCM drugs. Cardiac insufficiency of degree I and II can be simply treated with Chinese drugs. However, the western medicine ACEI is suggested to be used at the same time. For heart failure of degree III, measures of the western medical treatment sh...
8,797
Sudden death in a patient with multiple left anterior descending coronary artery fistulas to the left ventricle.
Coronary fistulas to cardiac chambers are an infrequent anomaly and usually are found casually. Although the majority of patients are asymptomatic, in rare cases it may cause coronary steal and cardiac ischemia. We present a patient with a left anterior descending coronary artery with multiple small fistulas to the lef...
8,798
Comparative antiarrhythmic efficacy of amiodarone and dronedarone during acute myocardial infarction in rats.
The effects of dronedarone, a non-iodinated derivative of amiodarone, on ventricular tachycardia and ventricular fibrillation post-myocardial infarction are not well established. Fifty-five Wistar rats were randomly allocated to a 2-week oral treatment with either vehicle (n=18), amiodarone (30 mg/kg, n=20), or droneda...
8,799
Post-shock synchronized pacing in isolated rabbit left ventricle: evaluation of a novel defibrillation strategy.
A failed near-threshold defibrillation shock is followed by an isoelectric window (IEW) and rapid repetitive responses that reinitiate ventricular fibrillation (VF). We hypothesized that properly timed (synchronized) postshock pacing stimuli (SyncP) may capture the recovered tissues during the repetitive responses and ...