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9,100 | Cost-effectiveness of automated external defibrillators in public places: con. | To discuss the clinical effectiveness, public health impact and cost-effectiveness of public access defibrillation.</AbstractText>High rates of survival from prehospital ventricular fibrillation have been documented in patients treated by first responders using automated external defibrillators. The recent Public Acces... |
9,101 | Gender differences in in-hospital mortality and mechanisms of death after the first acute myocardial infarction. | There are conflicting data about gender differences in short-term mortality after acute myocardial infarction (AMI) after adjusting for age and other prognostic factors. Therefore, we investigated the risk profile, clinical presentation, in-hospital mortality and mechanisms of death in women and men after the first AMI... |
9,102 | Prediction of intrapulmonary right to left shunt with left atrial size in patients with liver cirrhosis. | We screened a large number of liver transplant candidates with contrast echocardiography to detect intrapulmonary right to left shunt (IPS). We found that IPS is frequently present in patients with left atrial enlargement. This finding raises a question concerning the correlation between IPS and left atrial size in pat... |
9,103 | Innovative approaches to anti-arrhythmic drug therapy. | Normal cardiac function requires an appropriate and regular beating rate (cardiac rhythm). When the heart rhythm is too fast or too slow, cardiac function can be impaired, with derangements that vary from mild symptoms to life-threatening complications. Irregularities, particularly those involving excessively fast or s... |
9,104 | Ventricular fibrillation due to severe mitral valve prolapse. | Mitral valve prolapse usually has a good prognosis. However, an association between mitral valve prolapse and atrial and ventricular arrhythmias has been described. This case presents a patient who was admitted after cardiac resuscitation due to ventricular fibrillation. A severe mitral valve prolapse was the only path... |
9,105 | A comparison of electrically induced cardiac arrest with cardiac arrest produced by coronary occlusion. | The present study was undertaken to compare an animal model of electrically induced VF with ischemically induced VF. In a preponderance of models of cardiac arrest and resuscitation in intact animals, ventricular fibrillation (VF) is induced by an alternating current delivered directly to the epicardium or endocardium.... |
9,106 | Relation of arterial stiffness to left ventricular diastolic function and cardiovascular risk prediction in patients > or =65 years of age. | There is a paucity of data regarding the relation between the various noninvasive indexes of arterial stiffness and left ventricular diastolic function. In 188 subjects aged > or =65 years (mean 75 +/- 5; 71% men), the concordance and strength of the association between measures of arterial stiffness and left ventri... |
9,107 | P-wave dispersion is increased in pregnancy due to shortening of minimum duration of P: does this have clinical significance? | Most pregnant women complain of palpitation, and various kinds of arrhythmias can be observed during pregnancy. We investigated P-wave and QT dispersion during pregnancy. Healthy pregnant women (n=162) and healthy age-matched, non-pregnant women (n=150) were included. We performed electrocardiography and transthoracic ... |
9,108 | Modeling cardiac ischemia. | Myocardial ischemia is one of the main causes of sudden cardiac death, with 80% of victims suffering from coronary heart disease. In acute myocardial ischemia, the obstruction of coronary flow leads to the interruption of oxygen flow, glucose, and washout in the affected tissue. Cellular metabolism is impaired and seve... |
9,109 | [Ventricular fibrillation during induction of anesthesia in a patient with polycythemia vera]. | A 53-year-old male patient complained of the pain with bilateral hip area and right hip joint and underwent emergency arthroscopy and drainage. Twenty-eight years before, he had suffered from gout and from his abnormal increase of blood cells was diagnosed as polycythemia vera. The laboratory examination at admission s... |
9,110 | Prevalence of abnormal urinary albumin excretion rate in hypertensive patients with impaired fasting glucose and its association with cardiovascular disease. | The prevalence and significance of microalbuminuria in hypertensive patients with impaired fasting glucose (IFG) has received very little attention. A total of 10,320 hypertensive patients who attended primary care centers were enrolled in this study, and the final analysis was done in 7625 patients: 1459 without IFG (... |
9,111 | Familial idiopathic atrial fibrillation with fetal bradyarrhythmia. | A woman presented at 28 wk gestation with fetal bradycardia 50 bpm, which persisted until 42 wk when an asymptomatic male baby was delivered. Electrocardiograph at 3 wk of age documented an incessant atrial fibrillation with slow ventricular response. He continued to be asymptomatic, but on follow-up at 16 y of age, 24... |
9,112 | Fractionation of memory in medial temporal lobe amnesia. | We report a comprehensive investigation of the anterograde memory functions of two patients with memory impairments (RH and JC). RH had neuroradiological evidence of apparently selective right-sided hippocampal damage and an intact cognitive profile apart from selective memory impairments. JC, had neuroradiological evi... |
9,113 | [Utility of vasopressin in cardiopulmonary resuscitation]. | Many vasopressants have been studied in cardiopulmonary resuscitation (CPR) to increase cerebral and coronary perfusion. Although there is a debate on the utility of epinephrine, this is the one that has been used historically, above all after verifying that other agents such as norepinephrine, metoxamine or phenylephr... |
9,114 | Prognostic value of the Doppler index of myocardial performance in postoperative of coronary artery bypass surgery. | Myocardial Performance Index (MPI) obtained by Doppler echocardiography for the non-geometrical evaluation of systolic and diastolic function has been described as a method for prognostic evaluation in patients with acute myocardial infarction (AMI). Using the same condition, the objective of this study was to evaluate... |
9,115 | Bi-atrial subxiphoid epicardial pacemaker in superior vena cava syndrome. | A patient with a bi-atrial-ventricular permanent pacemaker due to paroxystic atrial fibrillation associated to sinus bradycardia, in chronic use of oral anticoagulant, presented clinical signs of superior vena cava syndrome. Digital subtraction venography showed total obstruction of the right brachiocephalic venous tru... |
9,116 | Clinical and electrophysiological characteristics of binodal disease. | Although coexistence of atrioventricular conduction disturbances with sick sinus syndrome (SSS), so-called binodal disease (BND), is a frequently encountered disorder, its clinical significance and electrophysiological characteristics remain unknown.</AbstractText>One hundred and seven patients with SSS were divided in... |
9,117 | Atrial electrophysiological abnormality in patients with Brugada syndrome assessed by P-wave signal-averaged ECG and programmed atrial stimulation. | There is evidence that some patients with Brugada syndrome (BS) exhibit atrial tachyarrhythmias including paroxysmal atrial fibrillation. We investigated whether BS associated not only with vulnerability to ventricular fibrillation, but also with vulnerability to atrial fibrillation.</AbstractText>In 15 patients with B... |
9,118 | Left ventricular remodeling of hypertrophic cardiomyopathy: longitudinal observation in rural community. | The purpose of the present study was to assess the clinical long-term course of hypertrophic cardiomyopathy (HCM) in a rural Japanese cohort.</AbstractText>A total of 137 consecutive HCM patients (mean age at diagnosis: 52+/-13 years) were enrolled. During a follow-up period of 11.4+/-5.7 years, 28 patients died of HCM... |
9,119 | Antioxidants decrease reperfusion induced arrhythmias in myocardial infarction with ST-elevation. | In myocardial infarctions with ST-segment elevation, ischemia followed by reperfusion (IR) leads to arrhythmia, myocardial stunning and endothelial dysfunction injury by reactive oxygen species (ROS). To determine the impact of ROS, we examined the effect of antioxidant vitamins on biochemical changes and arrhythmias i... |
9,120 | Electrocardiographic findings in 888 patients > or =90 years of age. | The oldest old are the fastest growing component of many national populations. No large-scale analysis of electrocardiographic findings in this group exists to date. This study cataloged the frequencies of specific electrocardiographic (ECG) findings in the target population and compared the frequencies of these findin... |
9,121 | Does the type of out-of-hospital airway interfere with other cardiopulmonary resuscitation tasks? | Out-of-hospital rescuers often perform tracheal intubation (TI) prior to other cardiopulmonary resuscitation (CPR) interventions. TI is a complex and error-prone procedure that may interfere with other key resuscitation tasks. We compared the effects of TI versus esophageal tracheal combitube (ETC) insertion on the acc... |
9,122 | [Therapeutic success of a prospective cardioversion protocol for persistent atrial fibrillation]. | The best therapeutic approach for persistent atrial fibrillation has yet to be defined. Our aim was to investigate the effects of cardioversion in unselected patients with persistent atrial fibrillation who were treated according to a strict protocol involving pretreatment, cardioversion, and follow-up.</AbstractText>C... |
9,123 | Pharmacotherapy considerations in advanced cardiac life support. | Cardiac arrest and sudden cardiac death remain major causes of mortality. Early intervention has been facilitated by emergency medical response systems and the development of training programs in basic life support and advanced cardiac life support (ACLS). Despite the implementation of these programs, the likelihood of... |
9,124 | HLa-class II (DRB & DQB1) in Thai sudden unexplained death syndrome (Thai SUDS) families (Lai-Tai families). | Thai Sudden Unexplained Death Syndrome (Thai SUDS), or Lai-Tai, is a major health problem among rural residents of northeastern Thailand. The cause has been identified as a genetic disease. SUDS, a disorder found in Southeast Asia, is characterized by an abnormal electrocardiogram with ST-segment elevation in leads V1-... |
9,125 | Terlipressin as an adjunct vasopressor in refractory hypotension after tricyclic antidepressant intoxication. | To report the management of cardiovascular failure refractory to standard catecholamine therapy with terlipressin in a patient with tricyclic antidepressant (TCA) intoxication.</AbstractText>A 41-year-old woman, with suicidal ingestion of 11.25 g amitriptyline and 1500 mg diclofenac, was admitted to the emergency depar... |
9,126 | A case of symptomatic coronary artery fistula. | A 57-year-old man presented with dyspnea and presyncope on exertion. He had previously been diagnosed with hypertension, hypercholesterolemia and atrial fibrillation. A soft (grade II/VI), dynamic continuous murmur was noted in the mid precordium.</AbstractText>Electrocardiography, stress echocardiography and coronary ... |
9,127 | Emergency gastric ulcer complications in elderly. Factors affecting the morbidity and mortality in relation to therapeutic approaches. | In elderly the incidence of the emergency gastric ulcer complications, perforation and bleeding are increasing, with a difficult management of these patients for their concomitant diseases. The aim of this work is to analyze the therapeutical approach of emergency gastric ulcer complications in elderly patients, in ord... |
9,128 | Efficacy of radiofrequency catheter ablation in treatment of elderly patients with supraventricular tachyarrhythmias and ventricular tachycardia. | Radiofrequency catheter ablation was performed in 100 men and 81 women, mean age 78 +/- 5 years, referred for ablation of atrial flutter, supraventricular tachycardia, and ventricular tachycardia, and for ablation of the atrioventricular junction with permanent pacemaker implantation in patients with atrial fibrillatio... |
9,129 | Cardiac effects of postconditioning depend critically on the duration of index ischemia. | Postconditioning (POC) is known as the phenomenon whereby brief intermittent ischemia applied at the onset of reperfusion following index ischemia limits myocardial infarct size. Whereas there is evidence that the algorithm of the POC stimulus is an important determinant of the protective efficacy, the importance of th... |
9,130 | Downregulation of connexin40 and increased prevalence of atrial arrhythmias in transgenic mice with cardiac-restricted overexpression of tumor necrosis factor. | Atrial arrhythmias, primarily atrial fibrillation, have been independently associated with structural remodeling and with inflammation. We hypothesized that sustained inflammatory signaling by tumor necrosis factor (TNF) would lead to alterations both in underlying atrial myocardial structure and in atrial electrical c... |
9,131 | Amiodarone-induced thyroid dysfunction in clinical practice. | Amiodarone is a potent class III anti-arrhythmic drug used in clinical practice for the prophylaxis and treatment of many cardiac rhythm disturbances, ranging from paroxismal atrial fibrillation to life threatening ventricular tachyarrhythmias. Amiodarone often causes changes in thyroid function tests mainly related to... |
9,132 | [Do we use digitalis properly in the management of elderly patients suffering from the signs of chronic heart failure?]. | The indications of digoxin therapy has been significantly narrowed and also the effective target therapeutic blood level has been decreased (0.9 micromol/L) compared to the previously desired one.</AbstractText>In this retrospective trial the data of 60 consecutive patients over 65 years (25 male, 35 female, mean age 7... |
9,133 | Milrinone administered before ischemia or just after reperfusion, attenuates myocardial stunning in anesthetized swine. | We assessed the dose or timing effect of milrinone administered against myocardial stunning in 37 anesthetized open-chest swine.</AbstractText>All swine were subjected to 12-min ischemia followed by reperfusion to produce myocardial stunning. Group A (n = 12) received saline in place of milrinone both before and after ... |
9,134 | Epidemiology, trends, and outcome of out-of-hospital cardiac arrest of non-cardiac origin. | The majority of victims who experience out-of-hospital cardiac arrest (OHCA) have ventricular fibrillation (VF) as the presenting rhythm and are thought to have a cardiac etiology for their arrest. Over the past decade, the incidence of VF OHCA has declined. The aims of this study were to describe the epidemiology of O... |
9,135 | Amiodarone and polymorphic ventricular tachycardia: to slow down or to accelerate the underlying rhythm? | Polymorphic ventricular tachycardia (VT) comprises a variety of different subforms. Two patients were admitted to our hospital and developed polymorphic VT under treatment with amiodarone. However, each of them turned out to have a very different form of the arrhythmia and therefore required a different therapeutic app... |
9,136 | Changes in escape rhythms several years after radiofrequency ablation of the atrioventricular junction combined with pacemaker implantation. | Escape rhythm is thought to play a considerable role in protection against adverse outcome due to pacemaker malfunction. We studied the escape rhythms in 32 patients with supraventricular tachyarrhythmia refractory to medical therapy who underwent radiofrequency ablation of the atrioventricular junction combined with i... |
9,137 | Left atrial function in patients with a high C-reactive protein level and paroxysmal atrial fibrillation. | We evaluated left atrial dimensions and function in high C-reactive protein (CRP) patients with paroxysmal atrial fibrillation.</AbstractText>In patients with increased plasma levels of CRP left atrial dysfunction may enhance the occurrence of arrhythmias.</AbstractText>Two-dimensional and pulsed Doppler echocardiograp... |
9,138 | Outcome after implantation of a cardioverter-defibrillator in patients with Brugada syndrome: a multicenter study. | Brugada syndrome is an arrhythmogenic disease characterized by an increased risk of sudden cardiac death (SCD) by ventricular fibrillation. At present, an implantable cardioverter-defibrillator (ICD) is the recommended therapy in high-risk patients. This multicenter study reports the outcome of a large series of patien... |
9,139 | Intracellular calcium and vulnerability to fibrillation and defibrillation in Langendorff-perfused rabbit ventricles. | The role of intracellular calcium (Ca(i)) in defibrillation and vulnerability is unclear.</AbstractText>We simultaneously mapped epicardial membrane potential and Ca(i) during shock on T-wave episodes (n=104) and attempted defibrillation episodes (n=173) in 17 Langendorff-perfused rabbit ventricles. Unsuccessful and ty... |
9,140 | High plasma aldosterone levels on admission are associated with death in patients presenting with acute ST-elevation myocardial infarction. | Aldosterone, the final mediator of the renin-angiotensin-aldosterone pathway, is at its highest plasma levels at presentation for ST-elevation myocardial infarction (STEMI). Whether aldosterone level at presentation for STEMI is associated with adverse outcome remains unknown.</AbstractText>Plasma aldosterone levels we... |
9,141 | Dietary n-3 fatty acids promote arrhythmias during acute regional myocardial ischemia in isolated pig hearts. | Dietary supplementation with fish oil-derived n-3 fatty acids reduces mortality in patients with myocardial infarction, but may have adverse effects in angina patients. The underlying electrophysiologic mechanisms are poorly understood. We studied the arrhythmias and the electrophysiologic changes during regional ische... |
9,142 | Use of the implantable loop recorder in children and adolescents. | Recurrent but infrequent syncopes represent a diagnostic challenge, since they frequently remain unexplained despite extensive investigations. This applies specifically for patients who carry an increased risk of potentially lifethreatening arrhythmias, either due to congenital cardiac disease or primary electrical dis... |
9,143 | Permanent direct his bundle pacing does not induce ventricular dyssynchrony unlike conventional right ventricular apical pacing. An intrapatient acute comparison study. | Benefits of A-V synchrony during right ventricular apical pacing are neutralized by induction of ventricular dyssynchrony. Only a few data are reported about direct His bundle pacing influence on ventricular synchronism.</AbstractText>Was to assess the capability of direct His bundle pacing to prevent pacing-induced ve... |
9,144 | Intrathoracic pressure regulation for intracranial pressure management in normovolemic and hypovolemic pigs. | To evaluate the potential to use subatmospheric intrathoracic pressure to regulate intracranial pressure (ICP) in normovolemic and hypovolemic animals, we tested the hypothesis that mechanical devices designed to reduce intrathoracic pressure will decrease ICP in a dose-related manner. An inspiratory impedance threshol... |
9,145 | delta-Opioid-induced pharmacologic myocardial hibernation during cardiopulmonary resuscitation. | Cardiac arrest and cardiopulmonary resuscitation is an event of global myocardial ischemia and reperfusion, which is associated with severe postresuscitation myocardial dysfunction and fatal outcome. Evidence has demonstrated that mammalian hibernation is triggered by cyclic variation of a delta-opiate-like compound in... |
9,146 | Simultaneous blockade of alpha1- and beta-actions of epinephrine during cardiopulmonary resuscitation. | Experimental and clinical studies have implicated that alpha1- and beta-adrenergic effects of epinephrine significantly increased the severity of postresuscitation myocardial dysfunction by increasing myocardial oxygen consumption during ventricular fibrillation. This prompted experimental studies to investigate the ef... |
9,147 | Microcirculation during cardiac arrest and resuscitation. | Direct observations of the microcirculation using orthogonal polarization spectral imaging have attracted attention and revealed that, especially in cardiogenic and distributive shock, there is discordance between the macrocirculation and the microcirculation. We evaluated serial changes and the effects of epinephrine ... |
9,148 | Preterminal gasping and effects on the cardiac function. | Gasping, also known as agonal respirations, is the terminal pattern that occurs after anoxia or ischemia and is a universal phenomenon in mammals. In this article we review the physiology of gasping, the prevalence and significance of gasping in cardiac arrest, and the effects of gasping on cardiac function.</AbstractT... |
9,149 | Analysis of the ventricular fibrillation waveform in refibrillation. | Frustrating outcomes are driving investigation of alternative resuscitation protocols. Previous analysis of the ventricular fibrillation (VF) waveform has focused on guiding whether to shock immediately or to delay for delivery of cardiopulmonary resuscitation in the case of presenting VF. The same issues emerge in the... |
9,150 | Definition of successful defibrillation. | The definition of defibrillation shock "success" endorsed by the International Liaison Committee on Resuscitation since the publication of Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiac Care has been removal of ventricular fibrillation at 5 secs after shock delivery. Although this success crite... |
9,151 | Outcomes from out-of-hospital cardiac arrest in Detroit. | To determine the out-of-hospital cardiac arrest survival rate, and prevalence of modifiable factors associated with survival, in Detroit, Michigan, over a 6-month period of time in 2002.</AbstractText>A retrospective review of all out-of-hospital cardiac arrests responded to by the Detroit Fire Department, Division of ... |
9,152 | Assessment of CPR-D skills of nurses in Göteborg, Sweden and Espoo, Finland: teaching leadership makes a difference. | Construction of an effective in-hospital resuscitation programme is challenging. To document and analyse resuscitation skills assessment must provide reliable data. Benchmarking with a hospital having documented excellent results of in-hospital resuscitation is beneficial. The purpose of this study was to assess the re... |
9,153 | Candesartan in the prevention of relapsing atrial fibrillation. | Several studies have indicated that treatment with angiotensin converting enzyme (ACE) inhibitors and angiotensin II type 1 receptor blockers (ARBs) may reduce the incidence of atrial fibrillation (AF) in hypertensive patients and patients with left ventricular dysfunction. However, there is limited data on the effect ... |
9,154 | Study of the restitution of action potential duration using the artificial neural network. | It is widely accepted that the APD (action potential duration) restitution plays a key role in the initializing and maintaining of the reentry arrhythmias. The Luo-Rudy II models paced with different protocols showed that the current APD had a complex relation with the previous APDs and diastole intervals (DIs). This r... |
9,155 | Prevalence of arrhythmias and their risk factors mid- and long-term after the arterial switch operation. | Early results of the arterial switch operation (ASO) for transposition of the great arteries (TGA) are good, but there are few mid- and long-term data on postoperative arrhythmias, especially in Japan. In this study, clinical data on 624 1-year survivors who had an ASO between 1976 and 1995 were collected from six inst... |
9,156 | The effect of an adenosine and lidocaine intravenous infusion on myocardial high-energy phosphates and pH during regional ischemia in the rat model in vivo. | We have previously shown that an intravenous infusion of adenosine and lidocaine (AL) solution protects against death and severe arrhythmias and reduces infarct size in the in vivo rat model of regional ischemia. The aim of this study was to examine the relative changes of myocardial high-energy phosphates (ATP and PCr... |
9,157 | AICD treatment in 2004--state of the art. | Primary and secondary prevention of sudden cardiac death is not sufficiently assured by medication. The (automatic) implantable cardioverter/defibrillator ((A)ICD) is able to terminate life-threatening arrhythmias (ventricular fibrillation/flutter, ventricular tachycardia) reliably. The identification and care of risk ... |
9,158 | Outcome prediction for guidance of initial resuscitation protocol: Shock first or CPR first. | Ventricular fibrillation (VF) is treated optimally with a defibrillation shock shortly after patient collapse, but may benefit from initial cardiopulmonary resuscitation (CPR) if the shock is delayed. An objective measure of potential responsiveness to defibrillation could help decide optimal initial therapy.</Abstract... |
9,159 | Postresuscitation myocardial dysfunction: correlated factors and prognostic implications. | To evaluate the clinical factors correlated with postresuscitation myocardial dysfunction and the prognostic implication such dysfunction may have.</AbstractText>Prospective observational study in a university medical center</AbstractText>58 adult patients successfully resuscitated from nontraumatic out-of-hospital car... |
9,160 | Appropriate ICD therapy in patients with idiopathic dilated cardiomyopathy: long term follow-up. | The implantable cardioverter defibrillator (ICD) has proved effective in preventing sudden death and decreasing mortality in randomised secondary prevention trials. Some nonrandomized studies have reported different incidences and predictors of appropriate ICD therapy in patients with idiopathic dilated cardiomyopathy ... |
9,161 | Performance of a new single-chamber ICD algorithm: discrimination of supraventricular and ventricular tachycardia based on vector timing and correlation. | Interval- and morphology-based algorithms have been used in modern implantable cardioverter defibrillators (ICDs) to discriminate supraventricular tachycardia (SVT) from other rhythms. A newly developed ICD discrimination algorithm, Rhythm ID (Guidant Corporation, St Paul, MN, USA), uses both interval-based metrics and... |
9,162 | QT variability strongly predicts sudden cardiac death in asymptomatic subjects with mild or moderate left ventricular systolic dysfunction: a prospective study. | The most widely accepted marker for stratifying the risk of sudden cardiac death (SCD) in post myocardial infarction patients is a depressed left ventricular function. Left ventricular ejection fractions (EF) of 35% or less increase the risk of sudden death but values between 35 and 40% raise concern. The underlying pa... |
9,163 | Arterial minus end-tidal CO2 as a prognostic factor of hospital survival in patients resuscitated from cardiac arrest. | The purpose of this study was to determine the clinical value of arterial minus end-tidal CO(2) [P(a-et)CO(2)] and alveolar dead space ventilation ratio (V(dA)/V(t)) as indicators of hospital mortality in patients that have been resuscitated from cardiac arrest at emergency department.</AbstractText>Forty-four patients... |
9,164 | Structural and functional assessment of arrhythmogenic right ventricular dysplasia/cardiomyopathy by multi-slice computed tomography: comparison with cardiovascular magnetic resonance. | Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an uncommon inheritable cardiomyopathy involving predominant right ventricle with progressive fibrofatty tissue replacement. An integrated assessment of electrical, functional and anatomic abnormalities, in addition to personal and family history wou... |
9,165 | Myopotentials leading to ventricular fibrillation detection after advisory defibrillator generator replacement. | We present an unusual source of oversensing following an internal cardioverter-defibrillator generator change. The early appearance of reproducible myopotentials in the defibrillator sensing channel is usually due to a technical complication at the time of device implantation. Clues such as abrupt impedance change or r... |
9,166 | Evaluation of atrial thrombus formation and atrial appendage function in patients with pacemaker by transesophageal echocardiography. | Physiologic pacing is claimed to be superior to ventricular pacing in as much as it entails lower risk of atrial fibrillation, stroke, and atrial remodeling. There are few data on the relation between atrioventricular (AV) synchrony and atrial clot formation. Utilizing transesophageal echocardiography (TEE), this study... |
9,167 | Comparison of a standard versus accelerated dosing regimen for D,L-sotalol for the treatment of atrial and ventricular dysrhythmias. | The current recommended starting dose of sotalol is 80 mg orally twice per day, followed by a judicious increase in dosage every 3 days under continuous telemetry monitoring. We hypothesized that sotalol administered at a higher starting dose (120 or 160 mg twice daily) would allow a more rapid attainment of therapeuti... |
9,168 | Steeper restitution slopes across right ventricular endocardium in patients with cardiomyopathy at high risk of ventricular arrhythmias. | Steep action potential duration (APD) restitution slopes (>1) and spatial APD restitution heterogeneity provide the substrate for ventricular fibrillation in computational models and experimental studies. Their relationship to ventricular arrhythmia vulnerability in human cardiomyopathy has not been defined. Patient... |
9,169 | Panoramic optical mapping reveals continuous epicardial reentry during ventricular fibrillation in the isolated swine heart. | During ventricular fibrillation (VF), activation waves are fragmented and the heart cannot contract synchronously. It has been proposed that VF waves emanate from stable sources ("mother rotors"). Previously, we used new optical mapping technology to image VF wavefronts from nearly the entire epicardial surface of six ... |
9,170 | Syncopal monomorphic ventricular tachycardia with pleomorphism, sensitive to antitachycardia pacing in a patient with Brugada syndrome. | Polymorphic ventricular tachycardia and ventricular fibrillation are the most common arrhythmias in Brugada syndrome, causing syncope or sudden death. Sustained monomorphic ventricular tachycardias are rare in this context. We report the case of a 41-year-old man with repetitive syncopal episodes and an ajmaline-induce... |
9,171 | Single beat determination of regional myocardial strain measurements in patients with atrial fibrillation. | Atrial fibrillation (AF) and congestive heart failure share several features and often coexist in the same patients; therefore, serial assessment of regional myocardial function is important for patients with AF. However, the clinical assessment of regional myocardial function in AF is unreliable and difficult because ... |
9,172 | Mild therapeutic hypothermia after cardiac arrest - a nationwide survey on the implementation of the ILCOR guidelines in German intensive care units. | To investigate the implementation of mild therapeutic hypothermia (MTH) after cardiac arrest into clinical practice.</AbstractText>A structured evaluation questionnaire was sent to all German hospitals registered to have ICUs; 58% completed the survey. A total of 93 ICUs (24%) reported to use MTH. Of those, 93% started... |
9,173 | Rapidly induced hypothermia with extracorporeal lung and heart assist (ECLHA) improves the neurological outcome after prolonged cardiac arrest in dogs. | We reported previously that therapeutic hypothermia with extracorporeal lung and heart assist (ECLHA) improved neurological outcome after 15 min cardiac arrest (CA) in dogs, although 45 min was needed to achieve hypothermia. We now investigate whether rapidly induced hypothermia with ECLHA (RHE) would result in a bette... |
9,174 | An unusual cause of atrial fibrillation: exposure to insecticides. | Although there are many well-known cardiac results of insecticide poisoning, atrial fibrillation (AF) has not been reported as the result of insecticide intoxication.</AbstractText>Twenty-six-year-old male, complaining of nausea and vomiting, presented to the emergency department with a history of methomyl dust exposur... |
9,175 | Underuse of standard care and outcome of patients with acute myocardial infarction and chronic renal insufficiency. | To investigate characteristics, management and outcome of patients with acute myocardial infarction (AMI) and chronic renal insufficiency (CRI).</AbstractText>Patients with AMI and CRI are considered to be at high risk of complications and death. Physicians may be reluctant to prescribe life-saving medications to patie... |
9,176 | Up-regulation of the inward rectifier K+ current (I K1) in the mouse heart accelerates and stabilizes rotors. | Previous studies have suggested an important role for the inward rectifier K+ current (I K1) in stabilizing rotors responsible for ventricular tachycardia (VT) and fibrillation (VF). To test this hypothesis, we used a line of transgenic mice (TG) overexpressing Kir 2.1-green fluorescent protein (GFP) fusion protein in ... |
9,177 | Increased survival despite a reduction in out-of-hospital ventricular fibrillation in north-east Italy. | We have reported the epidemiology and survival rate of out-of-hospital cardiac arrest (OOH-CA) in a north-east region of Italy previously, the Friuli-Venezia-Giulia Arrest Cooperative Study (FACS). We present the results of a second observational, prospective, multicentre study on OOH-CA victims in a local area in the ... |
9,178 | Growth hormone decreases phase II ventricular tachyarrhythmias during acute myocardial infarction in rats. | GH (growth hormone) administration during acute MI (myocardial infarction) ameliorates subsequent LV (left ventricular) dysfunction. In the present study, we examined the effects of such treatment on arrhythmogenesis. A total of 53 Wistar rats (218+/-17 g) were randomized into two groups receiving two intraperitoneal i... |
9,179 | [Treatment of hydroxychloroquine poisoning with extracorporeal circulation]. | We report a case of massive overdose of hydroxychloroquine treated with circulatory assistance by peripheral extracorporeal circulation (ECC). We expose the case of a 39-year-old woman who ingested 12 g of hydroxychloroquine with bromazepam, paroxetine, and zolpidem, in a suicide attempt. Patient has developed central ... |
9,180 | Imaging of left main coronary artery dissection with multislice computed tomography. | We occurred in a left main (LM) dissection during primary coronary intervention in a 45-year-old man with anterior acute myocardial infarction. Successful, multiple direct stenting was performed from the ostial to the mid left anterior descending coronary artery (LAD). Nonetheless, an LM dissection involving the proxim... |
9,181 | A case of a borderline-broad complex tachycardia. | Prompt and correct treatment of broad complex tachycardias in the emergency department can often be life-saving to the patient and satisfying for the emergency physician. They, however, are often a diagnostic challenge. Here, we present a case of posterior fascicular ventricular tachycardia, an idiopathic form of ventr... |
9,182 | Improved electrodes for electrical defibrillation of rats. | Experimental induction of ventricular fibrillation in animals yields valuable information about this deadly arrhythmia. Human adult or pediatric defibrillators and their paddles can be used easily in larger animals such as dogs and pigs, but these animals are more difficult to house and handle, and available biochemica... |
9,183 | [A case of Brugada syndrome with convulsive seizure during antidepressant administration: relation of antidepressant agents and arrhythmia leading to sudden death]. | Brugada syndrome is an arrhythmogenetic disease characterized by electrocardiographic ST segment elevation in right precordial leads, which is called "coved type", and an increased risk of sudden death as the result of ventricular fibrillation. We presented a case of Brugada syndrome with a convulsive seizure, during a... |
9,184 | [From implantable cardioverter-defibrillator to cardiac resynchronization therapy with the use of epicardial left ventricular lead. The evolution of the treatment of post inflammatory heart failure--a case report]. | The authors present a case of a 77-year-old man with heart failure in the course of dilated cardiomyopathy (DCM) and atrial fibrillation (AF), after implantation of an automatic cardioverter-defibrillator (ICD) due to recurrent symptomatic ventricular tachycardia (VT). Addition of cardiac resynchronization therapy (CRT... |
9,185 | Atrial fibrillation onset circumstances and their relation to patients' quality of life. | As assessed by patients, paroxysmal atrial fibrillation (AF) is very bothersome and significantly decreases quality of life (QoL).</AbstractText>To learn the circumstances that patients attribute to the onset of episodes of paroxysmal AF and attempt to characterise the psychological importance of these situations and t... |
9,186 | Right ventricular apex versus right ventricular outflow tract pacing: prospective, randomised, long-term clinical and echocardiographic evaluation. | In patients treated with permanent pacing, the electrode is typically placed in the right ventricular apex (RVA). Published data indicate that such electrode placement leads to an unfavourable ventricular depolarization pattern, while right ventricular outflow tract (RVOT) pacing seems to be more physiological.</Abstra... |
9,187 | Detection of ventricular fibrillation in the presence of cardiopulmonary resuscitation artefacts. | Providing cardiopulmonary resuscitation (CPR) to a patient in cardiac arrest introduces artefacts into the electrocardiogram (ECG), corrupting the diagnosis of the underlying heart rhythm. CPR must therefore be discontinued for reliable shock advice analysis by an automated external defibrillator (AED). Detection of ve... |
9,188 | On-pump beating-heart mitral valve plasty without aortic cross-clamping. | Patients with ischemic cardiomyopathy often have mitral regurgitation, which should be corrected for better long-term survival. Mitral valve surgery is usually performed during cardiopulmonary bypass under the arrested heart condition. The ascending aorta is cross-clamped and the heart is arrested using a cardioplegic ... |
9,189 | Cardiac resynchronization therapy in chronic heart failure. | Cardiac resynchronisation therapy (CRT) has emerged as a treatment option for patients with severe, drug-refractory heart failure and signs of intraventricular dyssynchrony. In clinical trials CRT reduced the overall mortality, improved symptoms, exercise tolerance, and left ventricular function, as compared with optim... |
9,190 | From hypertension to heart failure -- are there better primary prevention strategies? | Although in the developed world the incidence of and mortality from coronary heart disease (CHD) and stroke have been declining over the last 15 years, heart failure is increasing in incidence, prevalence and overall mortality, despite advances in the diagnosis and management of the condition. Hypertension, alone or in... |
9,191 | Ryanodine receptors and ventricular arrhythmias: emerging trends in mutations, mechanisms and therapies. | It has been six years since the first reported link between mutations in the cardiac ryanodine receptor Ca(2+) release channel (RyR2) and catecholaminergic polymorphic ventricular tachycardia (CPVT), a malignant stress-induced arrhythmia. In this time, rapid advances have been made in identifying new mutations, and in ... |
9,192 | [Observation on the safety: clinical trail on intracoronary autologous bone marrow mononuclear cells transplantation for acute myocardial infarction]. | To investigate the safety of autologous bone marrow mononuclear cell (BM-MNCs) transplantation by intracoronary infusion in patients with acute myocardial infarction (AMI).</AbstractText>One hundred and eighty-four patients with AMI treated with percutaneous coronary intervention (PCI) were randomized in a 1:1 way to e... |
9,193 | Newly detected atrial fibrillation following dual chamber pacemaker implantation. | Pacemaker (PPM)-detected atrial high-rate episodes (AHREs) of even 5-minute duration may identify patients at increased risk for stroke and death. In this study, we sought to determine the incidence of newly detected atrial fibrillation (AF defined as an AHRE > or = 5 minutes) in patients following dual-chamber PPM ... |
9,194 | Reversal of left ventricular dysfunction following ablation of atrial fibrillation. | Evaluation of ventricular rate control in atrial fibrillation (AF) can be difficult, and the presence of an AF-induced ventricular cardiomyopathy due to intermittent poor rate control or other causes may be underestimated. The outcome with AF ablation in patients with a decreased left ventricular ejection fraction (LVE... |
9,195 | The Managed Ventricular pacing versus VVI 40 Pacing (MVP) Trial: clinical background, rationale, design, and implementation. | Implantable cardioverter defibrillators (ICDs) reduce mortality among appropriately selected patients who have had or are at risk for life-threatening ventricular arrhythmia. Right ventricular apical (RVA) pacing has been implicated in worsening heart failure and death. The optimal pacemaker mode for bradycardia suppor... |
9,196 | [Thrombo-embolic events in patients with mechanical prosthetic valves--echocardiography in diagnostic and therapeutic decision making]. | Mechanical prosthetic valves (PV) are prone to thrombosis which may result in death or cripple hood due to PV blockade and embolisation (EM). In most pts with clinical symptoms of PV thrombosis (TPV) and in pts with a history of EM transthoracic echocardiography (TTE) and Doppler echocardiography are sufficient in diag... |
9,197 | Documentation of dynamic electrocardiographic changes shortly after the onset of tako-tsubo cardiomyopathy. | A 76-year-old female with atrial fibrillation and prior cerebral infarction had chest discomfort during rehabilitation for left hemiparesis, and visited the nearby hospital. Her ECG, which was obtained 10 min after the onset, showed marked ST-segment elevation in leads I, II, III, aV(F) and V(2-6), and she was referred... |
9,198 | [Characteristics of action of various drugs blocking atrioventricular conduction (beta-blockers, verapamil, diltiazem) in constant fibrillation tachyarrhythmia. Is monotherapy optimal?]. | To characterize actions of beta-blockers and Ca antagonists (verapamil and diltiazem) on the rate, structure and parameters of ventricular rhythm variability in constant cardiac fibrillation (CCF) and to evaluate validity of monotherapy with these drugs.</AbstractText>Thirty patients with CCF (mean age 64.5 +/- 9.5 yea... |
9,199 | Estimated risk of a first stroke and conditioning factors in Spanish hypertensive women. The RIMH study. | Stroke is the leading cause of mortality in women in Spain. RIMHA is a cross-sectional multicenter study in hypertensive women aged 55 or more in primary care to estimate the 10-year risk for a first stroke. Clinical history, cardiovascular risk factors and diseases, electrocardiogram, blood samples and blood pressure ... |
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