Datasets:
Javtor
/
biomedical-topic-categorization-validation

Dataset card Data Studio Files
xet
Community
PMID
int64
35.7M
36.4M
Title/Abstract
stringlengths
22
8.78k
MeshTerms
stringlengths
7
101
SemanticTypes
stringlengths
4
64
36,287,470
initi report panstrongylus rufotuberculatus champion triatomina hemiptera reduviida roraima western amazon state brazil studi first report speci panstrongylus rufotuberculatus roraima state northern brazil
D010203;D014225;D020064;D014355
T047;T204
36,287,469
anti sar cov antibodi immunoreact profil covid recurr studi aim evalu igg igm level covid recurr
D000086382
T047;T067
36,287,468
tuberculosi prison inmat southern brazil investig epidemiolog oper indic tuberculosi worldwid public health problem preval specif popul prison aim studi analyz epidemiolog oper indic tuberculosi prison southern region brazil
D014376;D014397;D011329;D015658
T047;T098
36,287,467
endophyt fungus phomopsi sp sourc nitropropion acid larvicid activ aed aegypti linnaeus diptera culicida aed aegypti primari vector virus zika chikungunya yellow fever dengu context biomonitor chemic studi conduct evalu activ crude extract endophyt fungus phomopsi sp larva aed aegypti
D000330;D003465;D000852;D007306;D000071244;D000071243
T131;T005;T204;T047
36,287,464
sea ice weddel sea relationship south atlant subtrop high precipit south america studi aim evalu posit intens south atlant subtrop high sash relat sea ice extent sie retract expans weddel sea assess precipit south america assess differ atmospher field relat sie four intens retract event minus four intens expans event februari end use nsidc sie era reanalysi chirp precipit icoad sst onisam index cpcnoaa follow month neutral enso sam observ tropospher warm weddel sea cool mid latitud south atlant weaken weddel sea circumpolar low high pressur tropic subtrop latitud addit equatorward shift ferrel cell therefor sash weaken contract result reduct tropic atlant moistur suppli south america negat precipit anomali tropic region similar suppress pattern south atlant converg zone result suggest sie retract expans weddel sea may contribut weaken strengthen sash earli end longer end drier end wetter end raini season tropic south america
D046448;D011891
T070
36,287,463
exposur climat risk case studi coffe farm region alta mogiana paulo studi around world show increas global averag temperatur consequ increas extrem event chang distribut precipit caus decreas agricultur product chang plant area studi analyz exposur climat risk coffe crop region alta mogianasp brazil present past thirti year time seri daili data maximum minimum temperatur precipit use statist test observ trend increas maximum temperatur daili approxim c minimum daili c municip region trend toward decreas precipit mm daili indic greater exposur coffe crop region climat risk increas vulner coffe produc view analys literatur review carri suggest agroforestri system mechan irrig promis strategi manag climat risk coffe plantat addit drought resist cultivar train cours farmer increas rural insur nutrit control plant also consid effici option climat exposur coffe plantat alta mogiana
D000383;D002980
T090;T070
36,287,461
qualiti follow preterm infant primari health care network qualipreterm guid develop first version assess guid qualiti follow preterm infant primari health care
D007234;D006293
T033;T058;T170;T100
36,287,460
epistemolog challeng indigen peopl research reflect base experi conceptu map discuss applic conceptu map under theoret anchor analyz challeng potenti method concern particip indigen peopl
D000081034;D019359
T098;T170
36,287,459
public polici social inclus higher educ extens practic ethnic group report experi operation univers extens project train affirm action student
D000083644;D005006
T098;T102;T054
36,287,436
intern trend pulmonari neuroendocrin cancer studi scientometr studi pulmonari neuroendocrin tumor account approxim primari lung tumor studi summar current bodi pulmonari neuroendocrin tumor studi worldwid
D002276;D018278;D008175;D018358
T191
36,287,435
brazilian famili hyperferritinemia cataract syndrom case report hereditari hyperferritinemia cataract syndrom rare autosom domin diseas caus genet mutat iron respons element untransl region ferritin light chain gene hereditari hyperferritinemia cataract syndrom character elev serum ferritin level bilater cataract develop earli life may misdiagnos hemochromatosi case report describ brazilian famili clinic diagnosi hereditari hyperferritinemia cataract syndrom submit ferritin light chain gene sequenc genet mutat c c g identifi untransl region conclus genet test use accur diagnosi hereditari hyperferritinemia cataract syndrom avoid misdiagnosi hemochromatosi diseas associ iron overload ophthalm diseas
D006432;D002386
T033;T047;T190
36,287,434
cancer symptom cluster lab bench clinic practic present discuss advanc scienc symptom manag research involv oncolog symptom cluster osc
D009369
T191
36,287,433
technolog nurs consult transsexu women light leining transcultur theori describ construct valid nurs consult technolog transgend women
D016746;D009732
T058;T091
36,287,432
empodereenf construct applic nurs continu educ psycholog violenc women construct prototyp mobil applic psycholog violenc women facilit nurs continu educ
D014754;D009726
T097;T048
36,287,429
relationship intrins extrins factor eros tooth wear adult cross section studi object studi explor relationship intrins extrins factor high cumul score basic eros wear examin bew chilean adult group cross section studi perform ethic committe approv universidad de los andes consecut adult year old sampl n health center san bernardo chile select septemb januari dental exam perform two train calibr examin accord bew index order search potenti relat factor hetero appli questionnair previous develop evalu appli interest individu sever eros tooth wear bew logist regress model report crude odd ratio adjust age confid interv ci p valu estim variabl odd ratio ci relat bew age current drink alcohol esophag difficulti swallow chest pain anorexia vitamin c intak age alcohol consumpt self report esophag histori gastric symptom anorexia vitamin c intak relat risk factor high bew score sampl chilean adult san bernardo chile
D014077;D057085;D004941
T047;T037
36,287,428
impact redistribut death ill defin caus oral oropharyng cancer mortal brazil less optim reliabl mortal inform system regard under caus death mask realiti oral oc oropharyng cancer opc mortal studi aim assess impact magnitud tempor trend oc opc mortal brazil two statist approach redistribut death ill defin under caus analyz death ill defin caus brazil macro region mortal inform system provid offici inform death two correct method appli ef method proport realloc death classifi r r icd remain specif caus death accord proport death certifi caus gbd method consid concept garbag code redistribut death sever icd chapter accord previous establish coeffici trend analysi mortal certifi redistribut prai winsten method carri oc opc death rate evid increas redistribut two techniqu region countri increas higher use gbd method northeast north region method doubl certifi death rate redistribut method also chang time seri trend epidemiolog studi mortal oc opc necessari redistribut death ill defin caus analyz data less optim inform system choic correct method critic epidemiolog studi must manag methodolog decis signific impact result
D007256;D009959
T170;T191;T073
36,287,427
impact covid gender gap dental public retrospect cohort three brazilian journal retrospect cohort studi investig impact covid pandem gender gap articl submit three intern dental journal base brazil submiss perform brazilian dental journal brazilian oral research journal appli oral scienc pandem assess gender first last correspond author collect variabl collect journal contin studi author stage career classifi accord author highest degre final decis reach articl absolut relat frequenc confid interv pearson chi squar test fisher exact test use total uniqu submiss analyz higher proport earli career author observ pandem p articl reject without associ gender increas proport male first author pandem observ p drop proport articl women first author observ research earli p mid career stage p reduct women first author observ pandem south central america p last author femal correspond author male conclus disproportion impact femal dental research submit articl period pandem observ consid first authorship suggest covid may increas gender inequ dental scienc
D000086382;D010506
T047;T170;T073;T067
36,287,426
heat treat niti instrument final irrig protocol biomechan prepar flatten canal studi evalu shape abil heat treat niti alloy instrument associ differ final irrig protocol flatten root canal thirti human mandibular incisor flatten root canal divid group n xp origin protocol xp endo shaper xp wt origin protocol xp endo shaper work time variat xp k xp endo shaper kinemat variat xp wtk xp endo shaper kinemat work time variat hyflex hyflex cm variat work time protocol sampl xp endo shaper group without kinemat variat use evalu final irrig protocol group submit protocol ni irrig n ci convent irrig n endovac irrig n sampl scan microcomput tomographi prepar scan electron microscopi evalu quantit data evalu use parametr anova test statist signific level set qualit data obtain compar establish agreement examin kappa test observ analysi xp endo shaper protocol addit work time caus differ paramet evalu p relat time recommend manufactur compar hyflex xp k show highest mean volum increas p lowest percentag untouch wall p qualit evalu final irrig protocol endovac provid best clean result associ xp k hyflex thus supplementari techniqu effect tool enhanc clean promot higher touch wall root canal prepar
D003786;D006358
T070;T030
36,287,425
associ citi region traumat dental injuri among adolesc santa maria south brazil studi investig associ citi region traumat dental injuri tdi among adolesc santa maria rio grand sul brazil popul base cross section survey conduct march novemb includ repres sampl adolesc year old attend public privat high school questionnair sociodemograph inform sent parentsleg guardian select adolesc tdi upper lower perman incisor canin record base obrien classif environment variabl sociodemograph structur characterist neighborhood obtain offici public multilevel poisson regress model use preval ratio pr confid interv ci calcul total adolesc particip studi overal preval tdi mild trauma sever trauma adolesc live southern region preval tdi compar northern region adjust import cofactor adolesc live southern region like tdi counterpart northern region pr ci p analyz number environment risk indic differ region southern region present higher mean median region conclus live southern region associ higher preval sever tdi among adolesc santa maria southern brazil find suggest role environ epidemiolog tdi
D018677
T037
36,287,424
absenc trichinella spp larva carcass road kill wild anim paran state brazil trichinella spp zoonot parasit wide distribut warm blood carnivor omnivor includ human present moment brazil consid world anim health organ free domest cycl trichinellosi wherea parasit sylvat cycl status infect limit zone howev neighbor countri argentina report parasit larva wild fauna present studi aim determin occurr trichinella spp road kill wild anim paran brazil biolog sampl wild anim didelphi albiventri nasua nasua ten cerdocyon thous seven dasypus novemcinctus six leopardus guttulus six sphiggurus spinosus two puma concolor collect novemb novemb subject artifici digest follow methodolog describ regul ec trichinella spp larva detect carcass road kill wild anim howev consid wide spectrum possibl reservoir could act link sylvat domest cycl consid current brazilian status sylvat trichinellosi limit zone frequent monitor wild fauna remain necessari
D014234;D014235;D046011;D045988
T047;T015;T204
36,287,423
avoid death first hour life health care reflex analyz risk death first hour life prevent caus
D007226;D003695
T081;T058;T093
36,287,422
therapeut lie brazilian speech languag therapist point view controversi communic strategi employ care peopl dementia object research obtain speech languag therapist point view use therapeut lie communic strategi dementia care
D013070;D003704
T061;T048
36,287,421
home languag environ relat languag outcom brazilian toddler hard hear control typic hear pilot studi includ reliabl analys lena record system purpos pilot studi explor home languag environ languag outcom brazilian toddler hard hear hh control typic hear th investig reliabl use lena record system within brazilian portugues context
D007802;D034381
T033;T171;T047
36,287,418
alopecia universali treatment simvastatin ezetimib affect famili alopecia areata aa autoimmun diseas grow scalp part bodi alopecia universali rare form alopecia areata character loss hair affect entir bodi two patient present studi atorvastatin treatment implement diagnosi hypercholesterolemia howev target valu reach combin simvastatin ezetimib implement period simvastatinezetimib treatment aa disord began hair loss scalp spread entir bodi turn alopecia universali although statin caus alopecia autoimmun reaction general use treatment alopecia due immunomodulatori effect
D000506;D019161
T121;T047;T109
36,287,415
vascular age arteri stiff biolog age occur result interact genet chronolog age extern factor basi new concept vascular age whose progress determin differ biolog chronolog age structur point view effect vascular age evid tunica media larg elast arteri mark increas arteri stiff lumen dilat wall thick effect describ continuum cardiovascular age propos dzau progress step microvasculatur lesion heart kidney brain initi age process increas arteri stiff detect sever non invas method cardiovascular event tradit describ use score combin convent risk factor atherosclerosi classic cardiovascular continuum dzau determin exact contribut risk factor challeng howev sinc arteri stiff reflect earli cumul damag cardiovascular risk factor indic actual damag arteri wall articl provid general overview pathophysiolog mechan arteri structur chang hemodynam consequ arteri stiff non invas method assess arteri stiff central blood pressur cardiovascular age continuum applic arteri stiff cardiovascular risk stratif
D059289;D002318
T047;T046
36,287,405
oviposit perform tephritid polyphag anastrepha fraterculus cerat capitata three period exposur fruit studi evalu oviposit behaviour anastrepha fraterculus wiedemann cerat capitata wiedemann five fruit speci appl guava mango peach tangerin expos infest hour anastrepha fraterculus c capitata show differ oviposit behaviour appl tangerin similar oviposit behaviour guava mango peach posit correl infest time pupaekg well pupaefruit surviv rate immatur pupal viabil studi present discuss oviposit behaviour fli host infest index index reflect reproduct capac fruit speci offer fli speci see adult recoveri rate greater highest infest index observ guava fraterculus per unit fruit peach c capitata per unit fruit understand reproduct capac host help risk analysi manag fruit fli
D033622;D033621;D031647;D002957;D031022
T168;T002;T204
36,287,404
new antioxid lauryl free herbal shampoo formul brazilian plant extract sodium lauryl sulfat main clean ingredi shampoo even though may potenti damag hair demand antioxid rich cosmet hand encourag green cosmet research brazil vast biodivers exploit product cosmet work aim develop minimalist antioxid lauryl free shampoo formul leaf extract brazilian plant hancornia speciosa gome two hydroethanol extract prepar use differ extract method soxhlet ultrasound extract character presenc saponin polyphenol quantif hlpc chemic identif compound antioxid activ determin use dpph method antioxid lauryl free shampoo develop use hydroxyethyl cellulos two concentr leaf extract obtain soxhlet mgg xp mgg xp along antioxid activ physic chemic properti clean potenti foam qualiti evalu soxhlet leaf extract reveal favor chemic profil includ posit result saponin well larger quantiti polyphenol increas antioxid activ xp formul show better foam height dirt dispers antioxid activ thus use mangabeira leaf extract appear promis develop shampoo antioxid activ
D000975;D012503
T123;T121;T109;T039;T044
36,287,403
effect auriculotherapi anxieti stress burnout health profession network meta analysi analyz effect auriculotherapi compar control group placebo usual treatment anxieti stress burnout health profession
D055097;D002055
T061;T048
36,287,402
creation valid high fidel simul scenario suicid postvent creat valid high fidel simul scenario initi support suicid bereav peopl
D001601;D000070856;D013405
T065;T033;T041
36,287,401
effect photobiomodul nm laser anthracyclin extravas experiment studi investig effect use differ agent topic hyaluronidas photobiomodul associ photobiomodul topic hyaluronidas prevent format lesion caus doxorubicin extravas well reduct lesion form extravas drug
D006940;D028022
T061;T047;T046
36,287,400
frailti delirium hospit older adult systemat review meta analysi estim preval synthes divers evid relationship frailti delirium hospit older adult
D000073496;D003693
T033;T184;T046;T048
36,287,399
clean hospit flexibl endoscop limit challeng analyz clean process gastroscop colonoscop duodenoscop eight hospit health servic
D004866;D003902
T120;T121;T073;T067
36,287,398
match matern knowledg infant develop care children one year old analyz matern knowledg infant develop match care offer children first year life
D002657;D009035
T092;T039;T040;T099
36,287,397
trend inequ self report cervic cancer screen brazilian capit studi aim verifi tempor trend inequ self report cervic cancer screen brazilian capit trend studi risk protect factor surveil system chronic non communic diseas telephon interview vigitel data outcom preval cytopatholog examin last three year slope index inequ sii concentr index cix use estim inequ increas trend outcom observ brazil period survey well decreas region capit group accord educ decreas coverag region brazil highlight sii present worst result reach pp ci pp ci respect among women year educ decreas coverag cervic cancer screen brazilian region capit period pandem reduct outcom observ south southeast region suggest covid pandem caus geograph inequ coverag exam brazil
D002583;D000086382
T047;T191;T067
36,287,396
use self help group peopl live hiv central america self help group shgs peopl live hiv plhiv organ creat communiti provid individu secur affect improv self esteem sens belong howev shgs also use govern help implement hiv control polici studi aim identifi characterist associ use shgs plhiv rout displac pattern adopt user analyt cross section studi conduct base data collect six central american countri use list shgs random sampl conduct two stage first shgs select select shgs visit everi third user attend shg survey logist regress model use identifi characterist associ use shgs attend nearest shgs spatial analysi perform identifi rout follow user reach shgs home communiti found characterist signific associ higher odd shg usag countri resid school level averag median distanc travel user attend shgs kilomet respect plhiv use shgs closest local perhap fear stigma discrimin recommend research topic use mix qualit quantit methodolog better understand util decis user expect degre met
D012657;D015658
T047;T095
36,287,308
pattern breast cancer second recurr patient mastectomi littl known second recurr breast cancer patient especi patient mastectomi aim determin risk factor preval pattern second recurr mastectomi patient first recurr
D001943;D016609
T191
36,287,307
popul health assess screen mammographi breast cancer mortal north carolina identifi predictor screen mammographi use effect screen mammographi breast cancer mortal north carolina
D001943;D000075485
T058;T191
36,287,292
influenza respiratori virus children preval clinic featur covid pandem still ongo annual season influenza respiratori virus epidem arriv specimen patient suspect respiratori virus infect collect viral detect perform follow rna extract real time rt pcr studi period receiv test total specimen rhinovirus virus viral type preval detect specimen age rang patient posit influenza influenza hn influenza b day year femal preval viral type cough asthma main clinic manifest present viral type result indic rhinovirus adenovirus metapneumovirus influenza among import agent ari pediatr epidem period respiratori infect observ goinia use plan implement prevent strategi
D007251;D053118;D000086382;D014780;D012141
T047;T005;T067
36,287,277
anthracyclin induc cardiotox cell senesc new therapeut option anthracyclin chemotherapeut drug wide use frontlin cancer treatment therapeut mechan involv stabil topoisomeras ii dna anthracyclin molecul ternari complex recogn dna damag redox imbal anoth vital sourc oxid dna damag togeth mechan lead cytotox effect neoplast cell howev anthracyclin treatment elicit cardiotox heart failur despit therapeut benefit topoisomeras ii oxid damag cardiac cell report pathophysiolog mechan altern cardiac cell undergo stress induc senesc expos anthracyclin state primarili character cell cycl arrest organell dysfunct shift senesc associ secretori phenotyp sasp sasp propag senesc neighbor cell ongo process lead accumul senesc cell promot cellular dysfunct extracellular matrix remodel therefor accumul senesc cardiac cell emerg pathophysiolog mechan associ anthracyclin induc cardiotox paradigm also rais potenti therapeut approach clear senesc cell treat anthracyclin induc cardiotox e senolyt therapi
D018943;D066126
T037;T109
36,287,276
percept pharmaci graduat student toward research ethic educ cross section studi develop countri despit potenti valu graduat level research ethic train middl east countri includ jordan routin offer formal research ethic train student enrol jordanian master level graduat program pharmaci current studi assess differ pre post enrol exposur research ethic core theme whether exposur formal cours inform set student attitud toward research ethic educ need integr dedic research ethic cours pharmaci graduat program item line survey develop author dissemin conveni sampl current former master level pharmaci student jordan total elig respond complet survey minor respond acknowledg receiv research ethic train prior enrol postgradu pharmaci program near half describ train inform comparison larger percentag total respond receiv research ethic train postgradu program enrol near half indic train inform major respond report strong need integr formal research ethic cours postgradu pharmaci curriculum support research train thesi write overal studi reveal notabl lack research ethic educ graduat level pharmaci student jordan
D013339;D010604
T091;T097;T057
36,287,275
carcass trait meat characterist graze nellor cattl submit differ supplement strategi tropic studi explor effect differ supplement strategi dri raini season tropic carcass trait meat qualiti nellor cattl produc graze condit addit cost assess supplement strategi conduct defin suitabl one econom standpoint twenti eight non castrat male anim month initi bodi weight kg use anim equit distribut random complet design thorough four supplement strategi follow miner supplement ms dri raini season msms ii ms dri season concentr supplement cs raini season mscs iii cs dri season ms raini season csms iv cs dri raini season cscs thereaft carcass trait primari carcass cut yield meat qualiti trait chemic composit meat cattl produc across differ supplement strategi determin data reveal anim cscs show greatest p carcass trait ribey area final ph forequart meat qualiti trait shear forc myofibrillar fragment index sarcomer length color meat chemic composit crude protein fat moistur anim cost assess supplement strategi reveal cscs highest product cost nevertheless cscs greatest incom profit msms lowest one conclus data suggest cattl graze tropic forag cs least one season ie dri raini produc similar meat qualiti trait chemic composit meat observ anim cs season addit last supplement strategi reveal greatest profit indic among explor
D053719;D008460
T063;T168
36,287,274
exopolysaccharid produc lactiplantibacillus plantarum ro isol romi chees character antioxid burn heal activ microbi exopolysaccharid epss extract lactic acid bacteria lab general recogn safe earn popular recent year except biolog featur therefor present studi main focus studi ep product probiot lab investig antioxid burn wound heal efficaci seventeen lab isol differ food sampl show ep produc abil rang gl ro isol romi chees chosen due abil produc highest ep yield gl rdna sequenc show belong lactiplantibacillus plantarum group identifi l plantarum ro access number ol display well vitro probiot properti rep extract character exist coo oh amid group correspond typic epss confirm via ftir constitut glucuron acid mannos glucos arabinos molar ratio respect averag molecular weight gmol vitro antioxid assay show rep possess dpph radic scaveng abil mgml reduc power mgml iron chelat activ mgml mgml respect heal efficaci rep burn wound model albino wistar rat show rep ww concentr stimul process heal burn area result suggest rep might use burn wound heal agent
D002611;D048191;D002056
T168;T007;T037
36,287,271
augment field fluoresc measur improv situ contamin detect research propos new method fuse data field lab base optic measur coupl machin learn algorithm quantifi concentr toxic contamin found fuel oil sand process affect water select pair excitationemiss intens key wavelength input augment neural network nn train use lab base measur generat synthet high resolut spectra imag process nn use estim contamin concentr spectra generat key wavelength present approach test use naphthen acid phenol fluoranthen pyren spike natur water spill loss contain contamin repres signific risk environ public health requir accur rapid detect method protect surround aquat environ result compar model base correspond peak intens contamin imag process nn use origin spectra naphthen acid fluoranthen pyren easi detect method howev perform challeng signal identifi phenol optim propos method peak pick mean absolut error mae gl generat excit emiss matrix mae gl result suggest data fusion machin learn techniqu improv detect contamin aquat environ environment relev concentr
D061329;D014874
T068;T070;T073;T131
36,287,267
screen medic error advers event use outlier detect screen algorithm inpati set evalu potenti novel system use outlier detect screen algorithm identifi medic relat risk inpati set
D050316;D020000
T058;T170;T073
36,287,261
distinct aspect placent epigenom theori aris placenta methylom dramat unlik somat cell type among distinct featur low global dna methyl extens partial methyl domain pack dens heterochromatin methyl hundr cpg island import somat develop featur attract interest part substanti fraction human cancer featur exact phenomena suggest parallel epigenom format placent cancer placenta also featur expand set imprint gene come distinct development pathway recent discoveri far outsid placent field shed new light unusu placent epigenet state may aris nonetheless key question remain unresolv
D000081122;D010920
T018;T028
36,287,256
rapid solid phase microextract dna use mesopor metal organ framework coat pcr base identif meat adulter rapid conveni low cost select dna isol method develop identifi meat adulter mesopor metal organ framework meso uio coat solid phase microextract system employ isol devic simplifi dna isol three step lysi wash elut meso uio util adsorb posit charg surfac high chemic stabil mesopor structur meso uio character scan electron microscopi transmiss electron microscopi powder x ray diffract fourier transform infrar spectroscopi ultravioletvis spectroscopi x ray photoelectron spectroscopi nitrogen adsorpt desorpt test paramet affect dna isol optim method use isol purifi dna meat dna concentr puriti compar sampl isol commerci kit multipl dna detect achiev coupl method multiplex polymeras chain reaction techniqu detect limit lower ww
D000073396
T109
36,287,255
mathemat model dengu transmiss intervent strategi use fraction deriv paper deal determinist mathemat model dengu base system fraction order differenti equat fode studi consid dengu control strategi relev current situat malaysia use adulticid larvicid destruct breed site individu protect global stabil diseas free equilibrium endem equilibrium construct use lyapunov function theori relat order oper control paramet briefli analys numer simul perform verifi theoret result examin signific intervent strategi control spread dengu communiti model show vector control tool effici method combat spread dengu virus combin individu protect make effect fact massiv use person protect alon signific reduc number dengu case invers mechan control alon suppress excess number infect popul although reduc aed mosquito popul result real data fit reveal fode model slight outperform integ order model thus suggest fode approach worth consid model infecti diseas like dengu
D003715;D000330
T047;T204
36,287,253
ecocentr biospher life extens biospher repres global sum ecosystem accord promin view environment ethic ecocentr ecosystem matter sake contribut human end ecocentrist critic modern industri civil even argu irrevers collaps modern industri civil would good thing howev take longer view consid eventu destruct biospher astronom process argu human speci consider technolog know industri capac could interven extend lifespan earth biospher perhap sever billion year argu human civil despit flaw harm impact mani ecosystem biospher best hope avoid prematur destruct argu propon ecocentr even wholli disregard anthropocentr valu strong moral reason preserv modern industri civil long need ensur biospher surviv
D017753;D008017
T070;T082;T102;T081;T068
36,287,250
multipl valu characterist fli ash indian coal thermal power plant review coal power thermal plant primari sourc energi product around globe half indian power plant use coal power product coal burn power plant result coal combust residu contain coal fli ash cfa recogn principl product cfa difficult character due broad composit variat henc present articl summar various physic chemic mineralog petrolog character cfa use differ applic indian coal thermal power plant found releas two type cfa f fine c coars cfa particl identifi unburn carbon particl larg fraction silica oxid alumina oxid iron oxid small fraction calcium oxid cao morpholog cfa particl spheric larg carbon molecul smooth textur surfac term mineralog quartz mullit magnetit hematit domin miner phase cfa tend non plastic permeabl level rang cms petrograph cfa enrich inertinit liptinit well collotelinit collodetrinit vitrodetrinit particl moreov cfa found compos various organ inorgan particl virtu multipl character util sever applic decad still quit limit therefor current studi aim provid help insight potenti use cfa deriv product differ way increas sustain
D060729;D003031
T121;T109;T131;T197;T130;T167
36,287,247
role speed technolog biolog inform transfer comput kind implement comput whether technolog biolog materi carrier inform exist real world implement propag speed inform exceed speed carrier limit one must also consid transfer time comput unit implement need differ mathemat method consid limit classic mathemat describ infinit fast small comput system implement differ mathemat handl method lead differ descript comput featur system propos handl also explain biolog implement lifelong learn technolog one conclus learn match publish experiment evid biolog technolog comput
D008433
T090
36,287,219
high sensit limit materi proteom empow data independ acquisit linear ion trap recent year concept cell heterogen biolog gain increas attent concomit push toward technolog capabl resolv biolog complex molecular level singl cell proteom use mass spectrometri scms low input proteom experi sensit orbitrap mass analyz sometim limit therefor low input proteom scms could benefit linear ion trap provid faster scan speed higher sensit orbitrap mass analyz howev cost resolut optim acquisit method combin orbitrap linear ion trap implement tribrid instrument take advantag high field asymmetr waveform ion mobil spectrometri faim pro interfac prime focus low input applic first compar perform orbitrap versus linear ion trap mass analyz subsequ optim critic method paramet low input measur data independ acquisit linear ion trap mass analyz conclud linear ion trap mass analyz combin faim whisper flow chromatographi well tailor low input proteom experi simultan increas throughput sensit larg scale proteom experi limit materi avail clinic sampl cellular subpopul
D040901;D010455
T121;T116;T091
36,287,215
hydrophob gate hydrophob gate flux ion channel common regul chang result steric occlus pore howev ion permeat also prevent format desolv barrier creat hydrophob residu line pore result relat minor structur chang confin hydrophob region channel may undergo transit wet dri state gate pore close without physic constrict permeat pathway concept refer hydrophob gate mani exampl process demonstr howev term also use much broader context often deviat origin mean viewpoint explor formal definit hydrophob gate discuss exampl process compar gate mechan simpli exploit hydrophob residu andor lipid steric closur pore describ best practic identif hydrophob gate
D015640;D008055
T109;T043
36,287,208
electr scooter relat injuri calgari emerg depart electr scooter e scooter contribut rise injuri burden emerg depart ed util sinc local introduct year ago studi novel collabor citi calgari depart transport emerg medicin research better understand natur frequenc e scooter injuri quantifi incid characterist e scooter relat injuri treat calgari edsurg care centr ucc
D004636;D004556
T037;T073;T093
36,287,203
nickel catalyz oxid carbonyl alkylaren arylacet acid catalyt system combin nibr diphenylphosphin oxid enabl direct access valuabl arylacet acid inexpens alkylaren h via oxid carbonyl develop alkylaren primari secondari benzyl c h bond compat method remark market drug ibuprofen diclofenac could easili obtain procedur straightforward
D009532;D018384
T123;T196;T049
36,287,201
label gold nanoparticl depot npd combin anti pd l antibodi strong inhibit growth tumor immunocompet mice induc abscop effect distant non irradi tumor effect normal tissu toxic novel nanoparticl depot npd brachytherapi seed incorpor gold nanoparticl aunp label particl emit term radiat nanomedicin studi treatment tripl negat murin mammari carcinoma tumor balbc mice induc abscop effect distant non irradi tumor alon combin anti pd l immun checkpoint antibodi balbc mice two subcutan tumorsa primari tumor distant secondari tumor implant intratumor primari tumor npd incorpor mbq aunp aunp unlabel aunp alon combin system administ anti pd l antibodi g ip three timesweek week receiv anti pd l antibodi alon treatment primari tumor strong growth inhibit npd incorpor aunp modest inhibit npd incorpor unlabel aunp anti pd l antibodi alon ineffect combin anti pd l antibodi npd incorpor aunp inhibit growth primari tumor secondari tumor growth inhibit treatment primari tumor npd incorpor aunp growth inhibit enhanc anti pd l antibodi treatment primari tumor npd incorpor unlabel aunp anti pd l antibodi alon effect secondari tumor growth biodistribut studi show high uptak primari tumor implant doseg idg low uptak secondari tumor idg normal tissu idg except kidney idg high radiat absorb dose estim primari tumor gy low dose secondari tumor gy highdos heterogen primari tumor dose high gy close proxim npd decreas rapid distanc npd normal organ dose low gy except kidney gy normal tissu toxic observ white blood cell count wbc decreas tumor bear mice treat npd incorpor aunp decreas wbc count interpret tumor respons toxic sinc higher healthi non tumor bear mice direct associ wbc count tumor burden conclud implant npd incorpor aunp primari tumor balbc mice strong inhibit tumor growth combin anti pd l antibodi induc abscop effect distant secondari tumor radiat nanomedicin promis local treatment tripl negat breast cancer tumor patient therapeut effect may extend non irradi lesion especi combin checkpoint immunotherapi
D006046;D053768
T121;T196;T073
36,287,193
access deoxi heptos construct one carbon homolog hexos malononitril diverg synthesi campylobact jejuni strain capsular trisaccharid repeat unit deriv effici approach deoxi heptos construct establish one carbon homolog sugar chain hexos reaction featur format sugar base substitut propanedinitril ensu divers oxid transform mild reaction condit compat wide rang sugar bear various functionalprotect group applic method demonstr diverg assembl campylobact jejuni strain capsular trisaccharid repeat unit deriv
D016123
T007
36,287,192
protect glomerulus role angiotensin ii type receptor podocyt injuri due either drug toxin infect metabol abnorm great concern increas risk develop focal segment glomerulosclerosi fsgs proteinur kidney diseas direct podocyt injuri due doxorubicin associ increas proinflammatori cytokin induct cathepsin l increas activ cathepsin l turn may degrad glomerular slit diaphragm result proteinur kidney injuri angiotensin ii type receptor atr earlier report associ preserv slit diaphragm protein prevent proteinuria recent vivo find zhang colleagu support anti proteinur role atr prevent podocyt injuri via regul cytokin ccl henc cathepsin l therebi limit progress fsgs
D005923;D050199;D007674
T047;T025
36,287,187
znf hypomethyl prognost biomark involv immun infiltr hepatocellular carcinoma associ cell cycl hepatocellular carcinoma hcc one dead common malign cancer around world prognosi hcc patient optimist znf belong krppel like zinc finger gene famili howev studi focus influenc znf hcc first analyz znf express hcc use data tcga icgc conduct joint analysi timer ualcan valid immunohistochemistri clinic hcc sampl appli ualcan explor correl znf express clinicopatholog characterist consequ use kaplan meier plotter analysi cox regress predict prognost valu znf hcc patient next analysi go kegg gsea reveal znf signific correl cell cycl immun final timer gepia analysi verifi znf express close relat tumor infiltr immun cell tiic includ b cell cd cell cd cell macrophag neutrophil dendrit cell analysi tcga icgc data set reveal znf express signific correl relat gene rbmx ythdf mettl conclus znf may prognost biomark relat immun candid liver cancer
D006528;D008113
T191
36,287,183
sex differ major cardiovascular outcom fractur patient subclin thyroid dysfunct systemat review meta analysi evalu whether sex differ associ subclin hypothyroid sh subclin hyperthyroid sch risk major advers cardiovascular event mace fractur
D006980;D007037;D013959;D006620
T047;T037
36,287,182
impact differ mechan metabol stimuli tempor dynam muscl strength adapt lambrianid epro g smith k mileva k jame karamanidi k impact differ mechan metabol stimuli tempor dynam muscl strength adapt j strength cond res fundament task exercis physiolog determin ultim improv adapt take place human bodi integr network various physiolog system exampl muscl tendon bone investig tempor dynam time cours adapt divers system may help us gain new knowledg function neuromotor system healthi patholog condit aim review explor tempor dynam muscular strength adapt studi implement resist train intervent addit categor studi mechan metabol stimuli identifi whether certain stimuli caus faster muscl strength gain search perform use pubm googl scholar databas review compris subject train group within studi met inclus criteria result reveal mean time point first signific increas muscl strength studi week correspond increas averag plateau muscl strength increas found occur week categor stimuli group reveal perform train hypox environ like produc leftward shift increas week dose respons relationship compar blood flow restrict supplement howev stimuli caus faster muscl strength gain may also induc imbalanc adapt muscl surround biolog structur potenti trigger degrad part network ie lead increas risk injuri
D018482;D055070
T061;T023;T024
36,287,181
effect long haul travel recoveri perform elit athlet systemat review rossit warrington gd comyn tm effect long haul travel recoveri perform elit athlet systemat review j strength cond res elit athlet often requir travel long haul lh across numer time zone train competit howev extent lh travel affect elit athlet perform remain larg unknown purpos systemat literatur review critic evalu avail evid effect lh travel elit athlet psychometr physiolog sleep perform marker electron databas search pubm sportdiscus scopus web scienc conduct accord prefer report item systemat review meta analys guidelin studi elig inclus subject identifi elit athlet embark lh flight hour use outcom measur recoveri perform flight studi retrospect use light therapi pharmacolog intervent includ record assess studi compris total athlet sport met inclus criteria increas perceiv jet lag disturb various physiolog marker lh travel howev minim disturb psychometr marker sleep negat affect lh travel studi assess perform found decrement indirect marker perform elit athlet perceiv jet lag experienc disturb various physiolog mechan lh travel howev effect perform inconclus futur research would benefit higher qualiti studi improv control measur larger sampl size wider varieti sport use ecolog valid measur circadian rhythm athlet perform
D020179;D054874
T055;T047
36,287,180
differenti respons strength gain limb resist train older women impact interlimb asymmetri reduct nune jp marcori aj ribeiro cunha pm kassiano w costa bdv aguiar af nakamura mayhew jl cyrino es differenti respons strength gain limb resist train older women impact interlimb asymmetri reduct j strength cond res present studi compar strength respons prefer pref nonpref n pref leg older women muscular strength measur unilater use isokinet dynamomet analyz reproduc score acut perform respons resist train rt program one hundr eleven women age year perform week whole bodi rt time week lower bodi exercis reproduc score intraclass correl coeffici follow test retest part sampl pretrain n averag acut perform averag strength gain pref n pref similar leg p howev individu analys show subject consid respond strength gain leg wherea nonrespond nonetheless consid respons strength test subject consid respond least measur addit observ strength ratio prefn pref leg alter present asymmetri baselin limb becam symmetr strength measur rt conclus observ older women may differ level strength leg howev tradit week rt program bilater exercis reduc asymmetri induc greater strength gain weaker leg
D055070
T061
36,287,179
sex differ perform depth field unit state olymp trial jobe tk shaffer hn doci cl gri kj sex differ perform depth field unit state olymp trial j strength cond res recent increas discuss role sex variabl human perform although like remain sociolog factor estim biolog sex differ human perform compar finish time elit men women sought determin effect sex run swim veloc depth field event vari length previous year finish time unit state olymp trial run event marathon freestyl swim collect sex differ veloc calcul year trend place first seventh depth field nth placefirst place signific set p men faster women run event p dash lowest sex differ compar race longer distanc p swim men faster event p sex differ general decreas longer distanc depth field similar men women run swim event differ analyz variabl observ data suggest elit men faster compar run race longer distanc sex differ swimmer tend get smaller durat increas although particip sociolog factor event may play role sex differ warrant discuss role sex athlet competit
D054874;D012420
T055;T056
36,287,174
comput studi new natur compound inhibitor traf nck interact kinas tnik traf nck interact kinas tnik downstream molecul wnt catenin signal pathway activ kinas catenint cell factor transcript complex fulli activ wnt signal promot growth invas tumor cell conduct comput assist virtual screen seri analys find potenti inhibitor tnik first libdock use molecular dock natur small molecul adm adsorpt distribut metabol excret analysi toxic predict perform top small molecul higher score addit order determin affin bind mechan tnik ligand analyz pharmacophor use cdocker accur molecular dock last least molecular dynam simul use evalu stabil receptor ligand complex natur environ result show natur small molecul zinc zinc high affin low interact energi tnik predict excel pharmacolog properti high plasma protein bind capac water solubl hepatotox blood brain barrier permeabl toler cytochrom p cypd addit less rodent carcinogen ame mutagen development toxic potenti molecular dynam simul show two compound could achiev stabil potenti energi root mean squar deviat rmsd differ time node studi prove zinc zinc ideal lead compound inhibit target tnik compound provid valuabl idea inform develop new colorect cancer target drug
D051176;D017346
T123;T126;T116
36,287,173
gabrb knock mice exhibit doubl direct pmdd like symptom gabaar subunit neurotransmitt metabol disrupt allopregnanolon bind premenstru dysphor disord pmdd sever mood disord patholog chang root gabrb copi number variat aim elucid gene dose effect allopregnanolon bind mechan gabrb possibl pmdd like comorbid phenotyp knockout mice
D065446
T048
36,287,172
combin stem cell rejuven senesc target synergist extend lifespan biolog age major risk factor mani import human diseas remain mysteri know organ age stem cell pool exhaust senesc cell progress accumul independ induct pluripot via express yamanaka factor oct klf sox c myc oksm clearanc senesc cell shown amelior cellular physiolog aspect age suggest process driver organism age stem cell exhaust cellular senesc like interact etiolog progress age depend diseas undermin tissu organ homeostasi differ complementari way combin transient cellular reprogram stem cell rejuven target remov senesc cell test hypothesi simultan target cell fate base age mechan maxim life health span benefit find oksm extend lifespan show intervent protect intestin stem cell pool lower inflamm activ pro stem cell signal pathway synergist improv health lifespan find suggest combin therapi simultan replac lost stem cell remov senesc cell show synergist potenti anti age treatment find transient express effect suggest drug base treatment non genet tractabl organ like translat
D008136;D012060
T061;T102;T079
36,287,147
asymmetr total synthesi havellock first total synthesi furanobutenolid deriv cembranoid diterpenoid havellock disclos converg strategi employ julia kocienski olefin join two enantioenrich fragment produc dien subsequ use propiol acid esterificationdiel alder cascad sequenc generat fuse carbocycl core natur product short order challeng zn mediat barbier allyl forg final c c bond also establish two vicin stereogen center final cu catalyz aerob oxid facilit format hydroxybutanolid complet total synthesi
D004224
T109
36,287,142
chang invertebr food web structur high low product environ driven intermedi top predat diet shift predat prey interact shape ecosystem stabil influenc chang ecosystem product howev multipl biotic abiot driver shape trophic respons predat product often observ pattern mechan product drive food web structur one way captur mechan shape trophic respons quantifi trophic interact among multipl trophic group use complementari metric trophic ecolog studi combin two diet trace method diet dna stabl isotop two trophic group top predat intermedi predat low high product habitat elucid food chain trophic structur shift respons chang under ecosystem product demonstr top predat show increas isotop trophic posit n product neither isotop nich size dna diet composit chang convers intermedi predat show clear turnov dna diet composit toward predatori prey base high product habitat take multi trophic approach highlight predat ident shape respons predat prey interact across environ differ under product build predict power understand outcom ongo anthropogen chang
D020387;D017753
T070;T082
36,287,063
amplif enrich sequenc mutagen methyl dna adduct specif pair unnatur nucleobas methylthymin mt long known chemic stabl strong mutagen dna base adduct howev sequenc method determin mt lack far two main obstacl includ capac mt stall dna elong low abund address challeng report unnatur base pair strategi paper new mt tpt base pair develop vmaxkm valu fold higher mt pair tpt nucleobas specif incorpor opposit mt base result mt tpt base pair effect extend give full length product presenc commerci dna polymeras import featur mt tpt pair enabl replac pcr amplif transfer mt lesion exact posit unnatur base pair permit sanger sequenc well biotin streptavidin base enrich mt lesion taken togeth work offer simpl conveni practic method amplif enrich sequenc mt first time
D018736;D009153
T123;T131;T114
36,287,035
sit emx nutrap mice simultan intact trap pair transcriptom epigenet sequenc epigenet regul transcript gain increas import studi neurobiolog advent sequenc technolog enabl studi regul across entir genom transcriptom howev modern method allow correl transcriptom data epigenom regul sever key limit includ use separ tissu sourc detect low express gene articl describ method combin isol nuclei tag specif cell type intact translat ribosom affin purif trap cell homogen refer simultan intact trap sit use technic approach direct coupl transcriptom sequenc epigenom data neuron deriv mous hippocampus demonstr method emx nutrap transgen mous model present protocol sit generat valid emx nutrap mous model use demonstr sit method enabl cell type specif comparison translat mrna chromatin data set cell use sit emx nutrap transgen mous model research compar epigenom data transcriptom data set hippocamp excitatori neuron author current protocol publish wiley period llc basic protocol emx nutrap transgen mous line label excitatori neuron hippocampus basic protocol sit simultan isol nuclei tag specif cell type intact translat ribosom affin purif trap
D059467;D044127
T081;T045;T086
36,287,034
sever pneumonia caus corynebacterium striatum adult seoul south korea investig proport characterist sever corynebacterium striatum pneumonia south korea part ongo observ studi sever pneumonia among adult patient identifi sever c striatum pneumonia case case hospit acquir patient immunocompromis c striatum case among patient sever hospit acquir pneumonia hap increas methicillin resist staphylococcus aureus mrsa infect among sever hap case decreas timefram c striatum respons sever hap case bacteri pathogen identifi day mortal rate similar high c striatum mrsa group c striatum major caus sever hap high mortal rate pathogen emerg possibl caus sever pneumonia especi among immunocompromis patient
D055624;D003428;D011014
T047;T007;T050
36,287,030
multispeci outbreak nocardia infect heart transplant recipi associ climat condit australia multispeci outbreak nocardia occur among heart transplant recipi htr lung transplant recipi ltr sydney new south wale australia perform retrospect review htr ltr nocardia spp infect june march compar risk factor nocardia infect evalu climat condit period outbreak compar ltr htr shorter median time transplant nocardia diagnosi higher preval diabet greater use induct immunosuppress basiliximab increas rate cellular reject nocardia diagnosi outbreak sydney experienc lowest month precipit driest surfac level compar time period direct outbreak increas immunosuppress htr compar ltr coupl extrem weather condit may explain outbreak nocardia infect htr
D009617;D009615;D016027
T061;T047;T007
36,287,021
miner compar proteom element analysi reveal ancestr composit iron miner molluscan radula radula uniqu forag organ mollusca import evolut taxonom classif mani radula miner metal although remark mechan properti miner radula well studi format miner nonminer radula poor understood take advantag recent sequenc octopus chiton genom abl identifi speci specif radular protein proteom compar proteom known limpet radula proteom enabl us gain insight molecular compon nonminer miner radula highlight iron miner chiton radula possibl due evolut ferritin peroxiredoxin vitro bind assay ferritin shown import iron accumul nonminer radula moreov radular proteom reflect adapt dietari habit extent octopus radula mani scaffold modif protein suit flexibl chiton radula abund sugar metabol protein eg glycosyl hydrolas adapt alga feed studi provid foundat understand molluscan radula format evolut may inspir synthesi iron nanomateri
D040901;D014070
T023;T091
36,286,995
use catalysi drive chemistri away equilibrium relat kinet asymmetri power stroke curtin hammett principl brownian ratchet chemic fuel autonom molecular machin catalysi driven system govern brownian inform ratchet mechan one fundament principl behind oper kinet asymmetri quantifi direct molecular motor howev difficult synthet chemist appli concept molecular design kinet asymmetri usual introduc abstract mathemat term involv experiment inaccess paramet furthermor two seem contradictori mechan propos chemic driven autonom molecular machin brownian ratchet power stroke mechan perspect address issu provid access experiment use design principl catalysi driven molecular machineri relat kinet asymmetri curtin hammett principl use synthet rotari motor kinesin walker illustr exampl approach describ molecular motor term brownian ratchet mechan pinpoint chemic gate power stroke tunabl design element affect kinet asymmetri explain approach kinet asymmetri consist previous one outlin condit power stroke use design element final discuss role inform concept use differ mean literatur hope perspect access broad rang chemist clarifi paramet use control design synthesi molecular machin relat system may also aid comprehens interdisciplinari understand biomolecular machineri
D007700
T070
36,286,989
target ccl ccr axi atheroprotect decad research establish atherosclerosi inflammatori diseas recent though clinic trial provid proof concept evid efficaci anti inflammatori strategi respect cardiovascular event thus offer new paradigm lower residu vascular risk effort target inflammasom interleukin interleukin pathway high success inter individu variat drug respons lack reduct caus mortal higher rate infect also highlight need second generat anti inflammatori agent target atherosclerosi specif immun mechan minim system side effect cc motif chemokin ligand monocyt chemoattract protein cclmcp orchestr inflammatori monocyt traffick bone marrow circul atherosclerot plaqu bind cognat receptor ccr ad strong bodi data experiment atherosclerosi model coher seri recent larg scale genet observ epidemiolog studi along data human atherosclerot plaqu highlight relev therapeut potenti ccl ccr axi human atherosclerosi summar experiment human data pinpoint ccl ccr pathway emerg drug target cardiovascular diseas furthermor contextu previous effort interfer pathway scrutin approach ligand target vs receptor target discuss possibl pathway intrins opportun challeng relat pharmacolog target ccl ccr axi human atherosclerot diseas
D058226;D050197
T047;T046;T020;T031
36,286,986
fabulus concert th anniversari yevdokimov moscow state univers medicin dentistri basi critic analysi sourc author reveal role doctor opera product ballet art general look opera libretto director product author make conclus characterist human health problem treatment method use social status doctor percent four hundr opera ballet product perform today includ doctor charact charact differ signific depend time creation work era reflect plot
D000846;D010820
T051;T052;T097
36,286,985
experi anticipatori therapi il receptor inhibitor perspect use evolut covid advisori board chair chief specialist infecti diseas ministri health russian feder professor vp chulanov held june saint petersburg aim main purpos board follow discuss analysi real world data levilimab anticipatori therapi covid hospit patient review experi perspect levilimab anticipatori anti inflammatori option outpati patient meet defin clinic laboratori criteria result analyz data clinic efficaci safeti form basi recommend propos expert use levilimab inpati outpati medic care covid
D000086382
T047;T067
36,286,984
modern extemporan formul geriatr care manag current opportun futur challeng review age associ disord includ cognit function often occur geriatr patient necessit use novel approach provid appropri medic care pharmacoprophylaxi pharmacotherapi among time import object nation healthcar system stimul pharmaceut compani pharmaci expand rang medicin intend elder patient also increas avail medicin product includ integr extemporan formul clinic practic present review consid sever featur regul use extemporan formul treatment geriatr patient exampl prescript use russian medic practic greatest interest treatment elder patient also present
D010594
T058;T073;T093
36,286,983
hyaluron acid treatment osteoarthr various local review articl discuss treatment osteoarthr oa preval high accord forecast increas next year author emphas high comorbid among patient suffer oa high cardiovascular gastrointestin risk frequent use nsaid volum consumpt constant increas discuss recommend treatment patient oa articl focus use hyaluron acid ha prepar treatment oa mechan anti inflammatori chondroprotect action ha joint effect cartilag synovi membran discuss attent drawn fact despit year experi effect use ha prepar treatment oa procedur still subject controversi among intern profession communiti articl present data meta analys systemat review confirm effect use intra articular manag ha prepar oa various local knee joint hip joint hand joint conclus recommend technic expert group establish intern symposium intra articular treatment given determin criteria success administr ha oa various local well predictor success non success therapi ha drug expert identifi indic contraind intra articular administr ha prepar well condit associ increas risk therapi failur conclus author draw conclus import use ha prepar intra articular administr treatment oa start earli stage follow recommend expert
D006820;D020370
T123;T121;T109;T122;T047
36,286,982
rational choos antibiot treatment cystiti recommend clinic pharmacologist review recent year harmon domest foreign clinic recommend treatment cystiti achiev nitrofuran fosfomycin trometamol recommend first line therapi antibiot oral rd generat cephalosporin recommend altern antibiot fluoroquinolon exclud recommend medic due unfavor safeti profil main rational inclus antibiot recommend first line therapi cystiti level resist uropathogen antibiot primarili escherichia coli stabl low level resist e coli russia note nitrofuran fosfomycin higher cephalosporin among nitrofuran furazidin character higher activ e coli compar nitrofurantoin potassium salt furazidin dosag form magnesium carbon prefer sinc character higher bioavail provid therapeut level concentr urin mic entir dose period due global increas resist uropathogen observ recent year expert begun pay attent ecolog safeti antimicrobi therapi order minim risk concomit collater damag contribut select multi drug resist strain microorgan latest document expert divid antibiot three group access watch reserv accord prioriti choic access group drug treatment cystiti includ nitrofurantoin furazidin agent minim collater effect fosfomycin trometamol cephalosporin list watch group thus standpoint ecolog safeti expert recommend prescrib nitrofuran treatment cystiti first line therapi
D005578;D003556;D009581;D014552
T121;T047;T195;T109
36,286,981
role interleukin human diseas pharmacotherapi prospect review accord current concept human immunoinflammatori diseas iid depend prevail mechan immunopathogenesi divid two main categori autoimmun autoinflammatori time autoimmun autoinflammatori mechan involv pathogenesi iid complex interact mechan reflect polymorph clinic present cours variant outcom therapi efficaci suggest iid overproduct cytokin interleukin il famili one key regul innat immun determin cross autoinflamm autoimmun mechan current anakinra recombin non glycosyl analog il receptor antagonist block il b il signal canakinumab monoclon antibodi il b use clinic practic inhibit patholog effect il analysi treatment outcom drug suggest il inhibit consid promis direct pharmacotherapi system autoinflammatori diseas critic condit associ hyperinflamm children adult
D007375;D053590
T129;T121;T116;T109
36,286,980
mask hide mitochondri neurogastrointestin encephalomyopathi case report first document case mitochondri neurogastrointestin encephalomyopathi describ r luft varieti biguiti clinic manifest diseas complic earli diagnosi treatment first clinic manifest diseas associ patholog gastrointestin tract low alert insuffici awar doctor delay time diagnosi mitochondri neurogastrointestin encephalomyopathi aim work increas alert awar narrow specialti possibl differenti diagnosi extrem rare detect diseas base clinic observ
D007418;D009886;D017237;D005767
T033;T184;T047
36,286,979
esophagoprotect therapi patient eros esophag evalu advantag use combin therapi proton pump inhibitor ppis esophagoprotector comparison basic therapi ppis week base result chang endoscop pictureto compar effect week ppi therapi week combin therapi ppi esophagoprotector alfasoxx sodium hyaluron chondroitin sulfat poloxom patient eros esophag ee degre accord los angel endoscop classif
D004941;D005764;D010437
T047
36,286,978
compar evalu effect narlaprevir composit interferon interferon free treatment regimen patient chronic hepat c aim give compar assess effect use narlaprevir combin pegyl interferon alpha peg ifn alpha interferon free mode patient chronic hepat c chc
D019698
T047
36,286,977
modif dietari pattern patient non alcohol steatohepat assess efficaci dietari pattern modif use special food patient non alcohol steatohepat nash
D065626;D008063
T121;T047;T127;T109
36,286,976
composit oropharyng microbiota patient covid differ pneumonia sever identifi featur taxonom composit oropharyng microbiota covid patient differ diseas sever
D000086382;D064307
T032;T067;T028;T047;T001
36,286,975
studi microcircul tissu metabol earli diagnost criteria risk diabet foot develop assess state microvasculatur tissu metabol reserv capabl purpos earli intervent prevent diabet foot syndrom
D017719;D008687;D003920
T121;T047;T109
36,286,974
epitheli protect therapi comorbid diseas practic guidelin physician document produc support nation medic associ studi comorbid nas first multidisciplinari nation consensus pathophysiolog clinic aspect increas epitheli permeabl syndrom publish propos guidelin develop basi consensus team expert twenti eight practic guidelin physician statement adopt expert council use delphic method main group epitheli protect drug proton pump inhibitor bismuth drug probiot discuss guidelin posit evid base medicin clinic pharmacolog characterist univers epitheli protector rebamipid act preepitheli epitheli subepitheli level throughout gastrointestin tract present detail
D054328;D010820
T121;T097
36,286,973
prospect person helicobact pylori erad therapi pro et contra articl devot debat aspect helicobact pylori erad therapi erad cancer prevent effect consid negat comorbid h pylori infect diseas gastroesophag reflux diseas inflammatori bowel diseas bronchial asthma describ perspect popul individu person strategi h pylori erad therapi assess given recommend individu h pylori erad strategi implement practic healthcar propos
D016480;D016481;D005764
T047;T007
36,286,972
classif system vascul evolut eponym modern criteria system vascul manifold group system autoimmun diseas character inflamm blood vessel first clinic case system vascul describ middl age current recognis nosolog form report first half th centuri first attempt creat unit classif vascul perform p zeek follow decad accumul data etiolog pathogenesi differ vascul guid research differ countri attempt improv classif main principl classif size affect blood vessel diseas etiolog pathogenesi american colleg rheumatolog acr publish classif criteria seven form system vascul gave signific contribut conduct larg scale studi field howev first intern nomenclatur vascul develop consensus confer chapel hill revis augment version nomenclatur creat still valid import step develop classif vascul joint project acr eular aim develop new diagnost classif criteria vascul dcvas first result project new classif criteria granulomatosi polyangi microscop polyangi eosinophil granulomatosi polyangi publish general evolut classif vascul occur influenc progress understand etiolog pathogenesi
D015267;D014890;D055953;D012219
T047;T091
36,286,971
non infecti diseas aorta larg arteri articl describ various form inflammatori lesion aorta larg arteri includ chronic periaort well diagnost method consid larg vessel vascul repres common entiti howev also associ rheumatolog inflammatori diseas drug induc paraneoplast entiti instrument imag modal play import role diagnosi
D013625;D013700;D000073296
T047
36,286,970
specif treatment asthen state focus sulbutiamin articl tri present avail data regard pharmacokinet pharmacodynam sulbutiamin enerion mechan anti asthen action analyz summar avail evid base consid efficaci safeti enerion treatment asthen syndrom compar enerion drug result review indic high efficaci safeti sulbutiamin treatment asthenia result also show enerion clinic relev advantag altern review
D001247;D013831
T184;T121;T127;T109
36,286,969
endogen estrogen defici develop chronic musculoskelet pain review sexual dimorph chronic diseas phenomenon determin differ hormon status men women regard estrogen complex effect bodi great interest particular estrogen play import role natur control pain inflamm decreas estrogen level associ menopaus iatrogen effect hysterectomi use aromotas inhibitor well mutat gene respons synthesi structur compon membran estrogen receptor esr esr signific reduc posit effect hormon defici estrogen becom one reason develop serious patholog chang particular format chronic pain associ patholog musculoskelet system
D059352;D059350;D004700
T033;T184;T047
36,286,968
efficaci safeti regdanvimab patient mildmoder covid high risk progress diseas retrospect studi short term stay unit use virus neutral monoclon antibodi effect method etiotrop therapi sar cov patient high risk group sever covid regdanvimab singl compon monoclon antibodi immunoglobulin g whose mechan action aim bind sar cov virus rbd site spike protein domain russian feder regdanvimab approv emerg administr covid adult patient requir respiratori therapi high risk develop sever cours diseas
D000086382
T047;T067
36,286,967
levilimab baricitinib prescrib experi outpati covid patient treatment studi effect levilimab baricitinib combin standard therapi st incid sever viral pneumonia associ new coronavirus infect covid
D000086382;D011024
T047;T067
36,286,966
difficult treat rheumatoid arthriti real clinic practic preliminari result compar featur cours diseas therapi rheumatoid arthriti ra patient meet criteria difficult treat ra dt
D001172;D018501
T121;T047
36,286,965
phenotyp bodi composit physic perform qualiti life women rheumatoid arthriti evalu frequenc differ bodi composit phenotyp physic perform pp relationship qualiti life women rheumatoid arthriti ra
D055948;D001172
T047
36,286,964
activ ankylos spondyl women within one year childbirth assess dynam activ ankylos spondyl year childbirth identifi predictor high activ
D013167;D018501
T121;T047
36,286,963
achiev clinic laboratori asa partial remiss patient earli axial spondyloarthr accord esac cohort rd year follow accord treat target strategi spondyloarthr spa main goal achiev clinic remiss inact diseas assess spondyloarhtr intern societi asa formul asa criteria partial remiss russian expert group studi spa identifi clinic laboratori remiss clinic manifest diseas persist month presenc normal valu c reactiv protein erythrocyt sediment rate magnet reson imag mri remiss complet remiss combin clinic laboratori mri remiss
D000089183;D025241
T047
36,286,962
immuno inflammatori rheumat diseas covid analysi clinic outcom accord data regist patient novosibirsk region receiv therapi genet engin biolog drug current observ accumul indic negat effect therapi number biolog diseas modifi anti rheumat drug bdmard drug cours covid fact determin relev studi factor sever cours unfavor outcom immuno inflammatori rheumat diseas iird patient treat bdmard order develop tactic manag categori patient pandem
D000086382;D012216;D011024;D018501;D001688
T121;T047;T123;T067