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36,282,696
experiment quantif interact drug deliveri system cell vitro guid preclin nanomedicin evalu major compon design drug deliveri system concern amplifi attenu interact specif cell type instanc chemotherapeut might function antibodi enhanc bind cancer cell target function polyethylen glycol help evad immun cell recognit stealth even cellular level optim bind uptak drug carrier complex biolog design problem thus valuabl separ strong new carrier interact cell function efficaci carrier cargo deliv cell continu chemotherapeut exampl well bind cancer cell separ problem well kill cancer cell quantit vitro assay latter well establish usual reli measur viabil howev publish research cell carrier interact qualit semiquantit general measur reli fluoresc label carrier consequ report interact cell relat arbitrari unit howev work standard made absolut quantit small number character experi absolut quantif valuabl facilit ration inter intra class comparison various drug deliveri system nanoparticl microparticl virus antibodi drug conjug engin therapeut cell extracellular vesicl furthermor quantif prerequisit subsequ meta analys silico model approach articl video guid well decis tree achiev vitro quantif carrier drug deliveri system present take account differ carrier size label modal addit consider quantit assess advanc drug deliveri system discuss intend serv valuabl resourc improv ration evalu design next generat medicin
D053758;D018796
T129;T121;T073
36,282,695
investig long distanc transport perfluoroalkyl acid wheat via split root exposur techniqu larg amount perfluoroalkyl acid pfaa introduc soil accumul plant pose potenti risk human health imper investig accumul transloc pfaa within plant long distanc transport import pathway pfaa transfer plant leav edibl tissu phloem howev previous difficult assess transloc potenti organ contamin short term exposur period split root experi provid solut effect uncov long distanc transloc pfaa use hydropon experi studi carri two ml centrifug tube b centrifug tube ml one quarter strength hoagland steril nutrient solut centrifug tube b amount nutrient concentr target pfaa perfluorooctan sulfon acid pfos perfluorooctan acid pfoa ad given concentr whole wheat root manual separ two part insert care tube b concentr pfaa root shoot wheat solut tube b evalu use lc msms respect cultur incub day harvest result suggest pfoa pfos experi similar long distanc transport process phloem shoot root could releas ambient environ thus split root techniqu use evalu long distanc transport differ chemic
D005466
T109
36,282,694
intramyocardi inject studi cardiac lymphat function zebrafish zebrafish prove import model studi cardiovascular format function postembryon develop regener present protocol describ method inject fluoresc tracer zebrafish myocardium studi interstiti fluid debri uptak cardiac lymphat vessel microspher nm diamet quantum dot nm diamet introduc myocardium live zebrafish track use ex vivo confoc microscopi tracer track intermitt sever hour follow clearanc myocardium cardiac lymphat vessel quantum dot transport cardiac lymphat vessel away heart larger microspher remain inject site three week method intramyocardi inject extend use includ inject encapsul ms hydrogel local releas cell protein compound interest target region heart
D015027;D042601
T023;T013
36,282,693
sourc rout pyrrolizidin alkaloid contamin tea sampl toxic pyrrolizidin alkaloid pas found tea sampl pose threat human health howev sourc rout pa contamin tea sampl remain unclear work adsorb method combin uplc msms develop determin pas weed ageratum conyzoid l conyzoid rhizospher soil fresh tea leav dri tea sampl averag recoveri rang relat standard deviat fifteen pair conyzoid conyzoid rhizospher soil sampl fresh tea leaf sampl collect jinzhai tea garden anhui provinc china analyz pas pas detect fresh tea leav except intermedin n oxid imno senecionin sn content imno gkg greater sn gkg addit imno sn concentr young leav tea plant content lower old leav result indic pas tea transfer path pa produc weed soil fresh tea leav tea garden
D053719;D011763
T063;T123;T131;T109
36,282,692
determin temperatur prefer mosquito ectotherm insect ectotherm relat narrow optim temperatur window deviat optima signific effect fit well characterist consequ mani ectotherm seek optim temperatur rang although temperatur prefer mosquito insect well studi tradit experiment setup perform use temperatur gradient aluminum surfac high enclos space case equip restrict mani natur behavior fli may import prefer select object studi observ insect prefer air temperatur use two chamber apparatus suffici room flight two chamber consist independ temperatur control incub larg apertur incub connect apertur use short acryl bridg insid incub two net cage link via apertur bridg allow insect freeli fli differ condit acryl bridg also act temperatur gradient two incub due spacious area cage easi construct method use studi small ectotherm andor manipul may alter temperatur prefer includ sensori organ manipul diet gut flora endosymbiont presenc biosafeti level bsl addit apparatus use studi pathogen infect use contain eg insid biosafeti cabinet bsl
D009033
T204
36,282,691
generat tissu spheroid via print stamp like devic advanc cell cultur develop physiolog relev vitro model tissu spheroid cell cultiv spheroid realist biolog respons resembl vivo environ due advantag tissu spheroid repres emerg trend toward superior reliabl predict studi model broad rang biotechnolog applic howev reproduc platform achiev larg scale product tissu spheroid becom unmet need fulli explor boost potenti herein larg scale product homogen tissu spheroid report use low cost time effect methodolog print stamp like devic develop generat spheroid per well plate devic fabric stereolithographi method use photocur resin final devic compos cylindr micropin height mm width approach allow fast generat homogen spheroid co cultur spheroid uniform shape size cell viabil moreov stamp like devic tunabl differ size well plate petri dish easili steril reus long period effici larg scale product homogen tissu spheroid essenti leverag translat multipl area industri tissu engin drug develop diseas model demand person medicin
D018874;D018929
T059;T025
36,282,690
frugal imag techniqu capillari flow three dimension polymer print powder develop novel imag techniqu molecular colloid transport includ nanoparticl area activ investig microfluid millifluid studi advent three dimension print new domain materi emerg therebi increas demand novel polym specif polymer powder averag particl size order micron experienc grow interest academ industri communiti control materi tunabl mesoscop microscop length scale creat opportun develop innov materi gradient materi recent need micron size polymer powder grow clear applic materi develop three dimension print provid high throughput process direct link new applic drive investig physio chemic transport interact mesoscal protocol discuss articl provid non invas techniqu imag fluid flow pack powder bed provid high tempor spatial resolut leverag mobil technolog readili avail mobil devic smartphon util common mobil devic imag cost would normal associ optic microscop elimin result frugal scienc approach propos protocol success character varieti combin fluid powder creat diagnost platform quick imag identifi optim combin fluid powder
D066330;D011108
T104;T122;T073
36,282,689
high spatial resolut chemic imag implant associ infect x ray excit luminesc chemic imag tissu microbi infect associ implant medic devic major concern fractur fixat failur earli diagnosi infect allow success erad antibiot without extra cost second surgeri herein describ xelci techniqu high x ray resolut implant specif chemic sensit noninvas imag chemic concentr near surfac implant medic devic devic coat chemic report surfac chemic respons surfac consist two layer coat implant medic devic ph sensit layer bromothymol blue bromocresol green incorpor hydrogel coat red light emit scintil gdos eu layer monitor focus x ray beam irradi spot implant red light generat scintil nm nm peak transmit sens layer alter spectral ratio depend ph imag generat scan x ray beam across implant measur spectral ratio light pass tissu point point use imag techniqu monitor implant associ infect previous bone surfac femur modifi implant plate sensor studi ph chang occur tibial intramedullari rod infect two differ type intramedullari rod design use pre pilot rabbit studi learn xelci techniqu could use monitor chemic chang occur bone surfac also insid bone thus enabl noninvas high spatial resolut low background local ph imag studi implant associ infect biochemistri
D049449;D001961
T070;T130;T109
36,282,688
prepar characterist toxic efficaci evalu nasal self assembl nanoemuls tumor vaccin vitro vivo epitop peptid attract widespread attent field tumor vaccin safeti high specif conveni product particular mhc restrict epitop induc effect cytotox lymphocyt activ clear tumor cell addit nasal administr effect safe deliveri techniqu tumor vaccin due conveni improv patient complianc howev epitop peptid unsuit nasal deliveri poor immunogen lack deliveri effici nanoemuls nes thermodynam stabl system load antigen deliv direct nasal mucos surfac ile lys val ala val ikvav core pentapeptid laminin integrin bind peptid express human respiratori epitheli cell studi intranas self assembl epitop peptid ne tumor vaccin contain synthet peptid ikvav ova ova prepar low energi emulsif method combin ikvav ova enhanc antigen uptak nasal mucos epitheli cell establish protocol studi physicochem characterist transmiss electron microscopi tem atom forc microscopi afm dynam light scatter dls stabil presenc mucin protein toxic examin cell viabil bea b cell nasal lung tissu cbl mice cellular uptak confoc laser scan microscopi clsm releas profil imag small anim vivo protect therapeut effect vaccin use eg tumor bear model anticip protocol provid technic theoret clue futur develop novel cell epitop peptid mucos vaccin
D019496
T129;T121;T116
36,282,687
isol quantif epstein barr virus phr cell line epstein barr virus ebv formal design human herpesvirus hhv first isol human tumor virus near world adult popul infect ebv recent advanc molecular biolog immunolog applic vitro vivo experiment model provid deep meaning insight pathogenesi ebv mani diseas well ebv associ tumorigenesi aim visual experi paper provid overview isol ebv viral particl cell phr cell line follow quantif viral prepar phr cell origin isol human burkitt lymphoma produc phr virus type ebv strain ebv lytic cycl induc phr cell treatment phorbol myrist acet pma yield ebv viral particl use protocol isol ebv particl phr cell cultur day c co complet rpmi medium contain ngml pma subsequ cultur medium centrifug speed x g min pellet cell virus contain supernat collect spun speed x g min pellet ebv particl viral pellet resuspend complet rpmi medium follow dna extract quantit real time pcr assess concentr ebv particl prepar
D004854;D020031
T005;T047
36,282,686
contact hypersensit murin model allerg contact dermat contact hypersensit chs experiment model allerg contact dermat acd studi mice studi aim present object laboratori method may help studi chs reaction mice measur quantifi various test induc chs day mice sensit previous shave spot abdomin skin paint hapten trinitrochlorobenzen tncb aceton ethanol mixtur wherea negat control mice sham sensit vehicl alon aceton ethanol mixtur day baselin ear thick measur micromet prior elicit chs challeng paint ear dilut tncb test control group h ear swell measur micromet chs exampl cell mediat immun respons caus swell inflam tissu peak h skin challeng hapten increas ear edema correl augment ear weight myeloperoxidas mpo activ pro inflammatori cytokin concentr ear extract increas thicken edemat dermi histolog examin ear vascular permeabl also increas concentr tnp specif igg antibodi sera test group compar control mice addit chs success transfer chs effector cell obtain donor previous sensit tncb chs effector cell administ intraven nave recipi mice subsequ challeng dilut hapten ear swell measur micromet h later
D009195;D017449
T047;T126;T116
36,282,685
imag acquisit use portabl sonographi emerg airway manag increas popular access portabl ultrasonographi rapid adapt improv periop care patient also address potenti benefit employ ultrasound airway manag benefit point care ultrasound pocus includ portabl speed util lack invas exposur patient radiat imag modal two primari indic airway pocus includ confirm endotrach intub identif cricothyroid membran event surgic airway requir articl techniqu use ultrasound confirm endotrach intub relev anatomi describ along associ ultrasonograph imag addit identif anatomi cricothyroid membran ultrasonograph acquisit appropri imag perform procedur review futur advanc includ util airway pocus identifi patient characterist might indic difficult airway manag tradit bedsid clinic exam best fair predict valu addit ultrasonograph airway assess potenti improv predict accuraci articl describ use pocus airway manag initi evid suggest improv diagnost accuraci predict difficult airway given one limit airway pocus requir skill sonograph imag analysi oper depend paper provid recommend standard technic aspect airway ultrasonographi promot research util sonographi airway manag goal protocol educ research medic health profession advanc research field airway pocus
D019095;D007830
T058;T023;T030
36,282,683
primari cultur porcin retin pigment epitheli cell retin pigment epithelium rpe monolay polar pigment epitheli cell locat choroid neuroretina retina multipl function includ phagocytosi nutrientmetabolit transport vitamin metabol etc conduct rpe daili basi rpe cell termin differenti epitheli cell littl regen capac loss rpe cell result multipl eye diseas lead visual impair age relat macular degener therefor establish vitro cultur model primari rpe cell close resembl rpe vivo cell line critic characterist mechanist studi rpe cell consid fact sourc human eyebal limit creat protocol cultur primari porcin rpe cell use protocol rpe cell easili dissoci adult porcin eyebal subsequ dissoci cell attach cultur dishesinsert prolifer form confluent monolay quick establish key featur epitheli tissu vivo within wks qrt pcr demonstr primari porcin rpe cell express multipl signatur gene compar level nativ rpe tissu express gene losthigh reduc human rpe like cell arp moreov immunofluoresc stain show distribut tight junction tissu polar cytoskeleton protein well presenc rpe isomeras critic vitamin metabol cultur primari cell altogeth develop easi follow approach cultur primari porcin rpe cell high puriti nativ rpe featur could serv good model understand rpe physiolog studi cell toxic facilit drug screen
D014801;D055213
T121;T023;T127;T109
36,282,682
comment articl risk factor associ lateonset neonat sepsi read great interest articl publish aria arellano santiago et al risk factor associ late neonat sepsi studi aim determin neonat risk factor use invas matern method associ neonat sepsi earli late neonatolog unit hospit ecuador
D000071074
T047
36,282,675
index revista mdica del imss revista mdica del imss face challeng maintain visibl articl within scienc communic process index bibliograph databas make scientif articl publish avail reader thank autom constant develop inform search retriev system index repres main mean reader consult articl regardless geograph locat educ special affili even nativ languag likewis allow generat bibliometr indic use evalu scientif product
D015706;D003142
T080;T062;T170;T054;T097
36,282,670
morpholog anatom surgic featur vermiform appendix histor review aim review focus light histori human vermiform appendix morpholog anatom surgic classif origin type blood suppli aspect order understand real function summar inform posit impact clinic decis case append popular surgic condit although characterist featur normal diseas appendix report mani previous centuri still common challeng face everi singl day oper room appendectomi commonest surgic emerg procedur may caus littl confus surgeon due high variabl situat insid abdomin caviti howev recent imag techniqu increas surgeon abil crucial diagnosi diseas appendix besid mention criteria clinic featur diagnosi manag author deepli search mani scientif databas includ embas cochran librari pubm pubm central pmc medlin web scienc scopus
D001065;D001064
T023;T047
36,282,669
medic sanit provis refuge irkutsk provinc basi archiv document articl studi provid inform creation medic sanitari bodi public organ provid refuge irkutsk provinc medic care carri comprehens anti epidem measur combat emerg epidem diseas characterist wartim studi show role medic sanitari bodi committe commiss ensur epidemiolog well refuge dynam increas number bed number hospit open infecti barrack increas financi alloc provis medic assist refuge note
D012036;D003141
T047;T098
36,282,668
civil healthcar eastern siberia eve begin great patriot war eastern siberia great patriot war deep rear one key region popul industri enterpris evacu front line zone west territori ussr among arriv popul mani high qualifi specialist sent along enterpris resum work one hand gave precondit develop region includ major industri scientif center futur also creat addit burden civil health care system region moment eastern siberia provid ussr healthi human necessari product resourc make possibl soviet armi defend motherland main thing difficult year face sudden invas nazi germani archiv materi give idea state civil health care system region begin first day great patriot war analyz compar analysi indic eastern siberia region individu republ rsfsr whole carri studi carri part research work state polici field health protect medic scienc russian empir ussr
D047789;D008887
T051;T091
36,282,667
problem railway medicin pirogov congress report organ medic care resettl articl devot problem medic sanitari support transport resettl rail russia begin th centuri basi perform histor reconstruct materi railway medicin section congress societi russian physician memori n pirogov
D008511;D010820
T091;T097
36,282,666
default pharmaceut market report predict estim seri articl research analyz signific default develop pharmaceut industri fate pharmaceut market particip second communic present result analysi predict statement collect memori repres pharmaceut communiti analysi carri basi interview publish pharmaceut public taken author articl total text use
D004345
T093
36,282,665
monitor evalu effect infecti control stomatolog organ kyrgyz republ paper highlight issu monitor assess state infect control conduct four year research order prevent infect associ provis medic dental care popul republ result present baselin period order predict scientif substanti prevent measur studi carri dental organ use evalu sheet state infect control dentistri includ criteria seven function organiz block method direct observ exist practic interview medic staff discuss causal relationship process phenomena qualit assess method calcul numer express percentag exist expect complianc infect control requir quantif result fourth monitor evalu indic complianc infect control requir show signific increas general time compar baselin monitor evalu function block infect control system growth rate rate increas p howev indic remain low requir improv system measur prevent infect associ provis dental care popul
D017053;D019242
T058;T091
36,282,664
communic doctor nurs teamwork articl deal issu communic doctor nurs attent paid obstacl affect effect communic doctor nurs includ increas workload constant chang staff use high tech terminolog previous negat experi communic nurs doctor etc recommend improv communic medic team given emphas factor contribut effect communic hospit organ provid primari health care multidisciplinari medic care plan drawn cooper patient caregiv
D010820;D009726
T097
36,282,663
analysi provis medic personnel subject north caucasus feder district articl present result compar analysi provis medic personnel differ indic provis specialist various profil studi note north caucasian feder district total valu medic servic densiti indic lower russian feder highest rate provis doctor regist republ ingushetia increas republ north ossetia higher valu provis indic head organ deputi establish north caucasus feder district russian feder time subject north caucasus feder district shortag specialist follow specialti anesthesiologist resuscit pediatr surgeon neonatologist pediatrician psychiatrist radiologist epidemiologist howev indic provis dentist north caucasus feder district exceed russian one time base analysi author present recommend includ need elimin shortag doctor number specialti increas admiss resid strengthen social support measur temporarili restrict admiss applic specialti dentistri etc
D013038;D010820
T078;T090;T097
36,282,662
issu educ children long term medic need healthcar organ articl present theoret analysi domest foreign experi teach children undergo long term treatment rehabilit context medic care specif educ process differ tradit classroom lesson system main role stakehold administr medic organ teacher children parent differ educ technolog well basic function educ children hospit school analyz
D012574;D010290
T092;T099;T102;T073
36,282,661
evid base propos improv zemski doctor program current attent paid shortag medic staff rural remot area order ensur staf medic institut worker rural area region one time compens paid part event call zemski doctor howev zemski doctor shown fade effect year implement includ due unwilling medic student particip program purpos work identifi attitud student medic univers particip zemski doctor program develop measur increas attract program achiev goal studi conduct survey medic student russia interview medic student medic staff includ former current particip novelti work lie studi attitud current potenti particip program order develop propos improv improv program necessari choos term conclud contract differenti payment depend distanc region center creat inform site defer armi durat contract
D019035;D013337
T058;T097;T073;T093
36,282,660
capric medicin equal respons medicin task technolog specif conflict manag multidisciplinari privat clinic articl substanti task introduc conflict manag system work privat sector medic organ reduc number ethic legal conflict aris provis medic care analysi conceptu foundat regulatori framework specif use conflict manag tool context solv organiz manageri task privat multidisciplinari clinic present
D017149;D008511
T098;T091;T057
36,282,659
improv organ labor qualiti medic care paramed obstetr station provis primari health care rural popul role paramed obstetr station fap great purpos studi develop system measur aim improv qualiti medic care provid paramed obstetr station studi conduct basi fap central district hospit crh republ dagestan organ labor paramed midwiv hour studi method time laps observ content visit fap popul analyz expert evalu method studi qualiti medic care patient fap main work fap paramed account midwiv labor cost signific share cost structur occupi prevent paramed midwiv diagnost therapeut activ high cost transit reloc work document structur visit popul paramed midwiv fap reason greatest proport visit therapeut diagnost purpos follow visit medic appoint prevent qualiti medic care provid paramed patient therapeut diseas inadequ case everi third patient treat fap unreason total number patient treat unreason fap accord expert treat crh district hospit outpati clinic
D000488;D004632
T093;T058;T097;T061
36,282,658
medic econom analysi effect structur unit medic organ medico econom analysi medic organ set techniqu method assess indic medic industri financi activ purpos choos way ration use intern resourc main object medic econom analysi determin reserv use organ resourc introduct effect technolog treatment process assess effect medic care assess effect manag decis combin type analysi subordin manag goal improv effici medic organ structur divis context increas competit medic servic market import medic econom analysi medic organ various form ownership grow state medic institut except modern autonom budgetari healthcar institut oper status independ econom entiti role chief physician organ medic econom process well role head structur unit must analyz result cost calcul need materi financi resourc determin effici medic activ subject analysi articl determin optim algorithm conduct medic econom analysi context function structur unit medic organ
D003695;D009938
T092;T058;T093
36,282,657
develop digit compet medic staff context overal digit russian healthcar relev studi due fact russian healthcar term pace qualiti digit lag behind healthcar system develop develop countri low level digit literaci medic staff allow develop proper level compet work high tech equip softwar applic various telemedicin servic turn reduc qualiti effici medic care popul purpos articl develop profil digit compet medic staff methodolog articl base use method statist analysi public data sociolog research sampl sociolog studi form medic staff region moscow tula bryansk sverdlovsk pace level digit russian healthcar sever order magnitud lower healthcar system unit state south korea japan oecd countri develop digit compet high level digit literaci observ among medic worker first oper high tech medic organ second among medic worker whose organ locat close region econom center russian healthcar need addit invest direct digit develop digit literaci medic staff assess digit literaci special digit compet profil middl senior medic personnel develop
D003695;D017216
T058;T093
36,282,656
research problem medic social work russian feder review dissert develop social work field health protect medic social work larg depend ongo scientif research topic review present analysi dissert demonstr research various aspect medic social work profession activ analyz studi cover year period begin first dissert work area dissert carri within framework medic sociolog pedagog scienc base interdisciplinari approach format modern system social work russian feder
D012947;D009790
T090;T057
36,282,655
social health peopl disabl context social chang absolut world constant increas number peopl disabl result number econom social ecolog demograph reason share disabl peopl territori pridnestrovian moldavian republ remain high recent year articl touch upon issu qualit indic social health peopl disabl give fundament characterist social health questionnair survey conduct februari among peopl disabl purpos addit studi interview peopl work age disabl conduct march result author research territori pridnestrovian moldavian republ among peopl disabl subject studi process social social adapt societi present base conduct quantit qualit research method main trend regard social health peopl disabl identifi main barrier way success integr process hinder social social adapt outlin result necessit modern current system target support peopl disabl
D012922;D006233
T101;T054;T080
36,282,654
specif aspect legisl consolid institut earli care children disabl purpos work children disabl includ disabl children children age year recogn disabl prescrib manner temporari perman deviat physic mental develop hereinaft children disabl legisl basi implement right opportun children disabl famili constitut constitut provis enshrin state guarante protect childhood motherhood patern famili part articl paragraph g part articl constitut russian feder earli start comprehens care children disabl contribut maximum possibl achiev develop child maintain health well success social inclus child educ environ subsequ integr societi research materi intern treati regulatori legal act russian feder provid earli assist children disabl work use set method scientif knowledg includ general scientif method analysi synthesi induct deduct special compar formal legal etc legisl consolid institut provid earli assist children disabl carri amend exist legisl act adopt separ regulatori legal act legisl level establish legal basi provid earli assist articl outlin direct improv legal regul term legisl consolid institut provid earli assist children disabl amend current legisl act feder level
D019988
T101
36,282,653
topic issu medic rehabilit patient consequ sever traumat brain injuri municip level articl present age sex structur peopl suffer sever traumat brain injuri exampl municip medic organ provid medic care medic rehabilit outpati set high preval type injuri among male work age establish durat temporari disabl time referr categori peopl medic social examin reflect high level disabl among peopl suffer sever traumat brain injuri case assign sever first second disabl group articl reflect personnel problem municip medic organ provid outpati medic care format multidisciplinari rehabilit team requir resolut region level
D001930;D000070642;D006233
T101;T037
36,282,652
satisfact resid circumpolar region state healthcar system depend level health literaci region arctic zone far north russia weak social infrastructur includ region segment state healthcar system studi citizen satisfact healthcar system one lead method assess effect citizen satisfact may distort health literaci hl half healthi citizen excel suffici level general gvh patient medic organ insuffici problemat level general hl level citizen satisfact domest healthcar determin clinic status higher group patient group healthi peopl patient evalu loyal comparison health peopl respond insuffici hl evalu health care system less loyal high level hl allow patient assess result work domest health care system object comparison healthi citizen aim studi assess satisfact resid circumpolar region russia arkhangelsk oblast region segment state healthcar system depend level hl
D057220
T041
36,282,651
evalu medic econom effici non invas prenat test moscow evalu medic econom effici prenat diagnost fetal chromosom abnorm ca pregnant women moscow use non invas prenat test nipt second line model compar analysi medic econom effici standard prenat screen prenat screen nipt group pregnant women regist moscow high medium fetal ca risk carri analysi base number children born ca cost medic care direct cost social payment indirect cost calcul scenario follow standard prenat screen children ca would born follow prenat screen nipt includ nipt prenat diagnost increas direct cost million rubl reduc annual indirect cost million rubl start th year use nipt estim effect reduc indirect cost would exceed direct cost nipt prenat diagnost increas detect fetal ca reduc indirect cost assess indirect cost econom effici enhanc accuraci estim
D004314
T047
36,282,650
monitor offici requir state health citizen militari age diseas nervous system articl provid analysi chang offici requir state health young men diseas nervous system regul militari medic examin amend column ii articl schedul diseas provis consid point view categori fit militari servic conscript set measur propos reduc consequ chang requir function state nervous system health futur conscript servicemen
D008889
T097
36,282,649
retrospect analysi incid rate popul republ tatarstan diseas endocrin system diseas endocrin system urgent medic social problem connect widespread preval negat growth trend throughout world often accompani chronic diseas lead disabl aim studi trend structur characterist morbid popul republ tatarstan diseas endocrin system studi base materi offici statist republ tatarstan period method descript statist linear regress analysi use indic primari morbid preval endocrin system diseas among various age group republ tatarstan studi retrospect analysi incid endocrin system diseas popul republ tatarstan indic format stabl negat trend growth preval thyroid diseas diabet obes among group studi increas primari incid preval thyroid diseas among children growth rate compar respect adolesc growth rate respect well increas preval type diabet group growth rate respect increas primari incid growth rate preval hypothyroid among children growth rate increas preval thyroid among adult growth rate rate increas primari incid obes year observ among children among adolesc among adult popul revers negat trend morbid believ necessari strengthen prevent work among age group form healthi eat habit maintain normal bodi weight take legisl decis mass prevent iodin defici endem region well conduct research aim assess impact risk factor caus impact endocrin disruptor health popul republ
D052244;D003924;D013959;D004700;D007455
T121;T123;T131;T196;T039;T047
36,282,648
epidemiolog featur papillomavirus infect cervic cancer republ bashkortostan kaliningrad region context improv cancer prevent program becom relev justifi introduct region hpv cervic cancer screen program base studi preval human papillomavirus infect cervic cancer aim identifi main pattern preval human papillomavirus infect cervic cancer bashkortostan kaliningrad region scientif substanti criteria adopt region screen program prospect analyt cohort singl stage observ examin women republ bashkortostan women kaliningrad region carri well retrospect observ analyt studi cervic cancer incid bashkiria kaliningrad region accord offici statist compar russian indic bashkortostan kaliningrad region hpv dna detect women reproduct age respect hpv high oncogen risk hpv hr found pcm kaliningrad region hpv dna detect women studi hpv vr accompani cervix uteri diseas increas incid note kaliningrad region year annual increas bashkortostan growth demonstr annual increas signific higher russian feder year preval cervic cancer increas kaliningrad region averag annual increas bashkortostan preval csm increas annual increas high preval hpv infect among women reproduct age unfavor dynam indic cervic hpv associ oncopatholog remot region russian feder bashkiria kaliningrad region scientif base criterion reorgan region cervic screen program implement organ screen primari hpv examin mandatori separ genotyp type remain type hpv hrc complex enhanc effect ongo prevent measur meet intern standard
D030361;D002583
T047;T191
36,282,647
assess nosolog structur associ anem syndrom anem syndrom stage primari health care deliveri outpati basi risk factor unfavor outcom patient chronic somat diseas primarili cardiovascular oncolog patholog order understand true preval anemia among outpati necessari improv registr patient diseas aim analyz featur manag patient anemia primari health care system use computer patient monitor system studi includ patient age dispensari observ famili physician analysi medic record comput program develop author monitor system patient anem syndrom use structur morbid two select area outpati depart context main class diseas icd analyz accord analysi medic record carri use program develop us anemia record patient analysi use comput regist accord criteria peopl anem syndrom indic underdiagnosi patholog condit need direct effort healthcar organ earli reveal patient anemia
D000740
T047
36,282,646
hygien assess nutrit incid individu diseas student secondari profession educ modern condit primari prevent signific number diseas today base principl healthi lifestyl import condit maintain strengthen health popul time one main task optim nutrit status preserv improv health certain group popul children adolesc purpos work hygien assess characterist nutrit status nutrit health young student scientif substanti recommend optim establish insuffici level knowledg basic healthi lifestyl exist shortcom organ nutrit adolesc well econom factor lead inadequ nutrit status student secondari profession educ express low energi valu diet imbal lack divers well low provis macronutri vitamin miner signific increas incid diseas digest system junior senior year allow us consid colleg educ risk factor diseas class
D009752;D004517
T033;T065
36,282,645
issu impact radioact substanc public health countermeasur radiat exposur global problem widespread use today world radioact sourc energi medicin engin construct contamin track food steril increas likelihood accident exposur use ioniz radiat radioact element direct indirect caus life threaten complic oncopatholog radiat burn impair immun pollut environ radioact element deplet ozon layer also contribut increas level radiat exposur protect health popul live contamin area consum local produc product necessari organ system monitor radioact damag well special anti radiat protect measur field agricultur forestri hunt fish provid popul food purpos studi analyz modern scientif data effect ioniz radiat reproduct function modern approach aim correct violat bibliograph inform analyt method method compar analysi use
D011634;D011832
T047;T091;T037
36,282,644
gender age featur preval hypertens popul medium urban citi central russia establish gender age characterist preval risk develop hypertens ah among outpati live citi tambov accord electron medic record emr inform emc peopl age live tambov use preval rate per peopl relat risk develop rr hypertens differ sex age group calcul preval hypertens among peopl age case women higher men vs case age increas preval hypertens year old peopl transit smaller age group larger one increas preval hypertens among femal cohort averag among male cohort averag rr develop hypertens among femal cohort age year time higher compar male cohort age age develop hypertens prevail among male cohort year old among femal cohort high level establish differ preval risk develop hypertens determin need develop recommend hypertens screen among popul stratif risk group prevent treatment focus differ age gender group
D006973
T047
36,282,643
determin qualiti life morbid adult popul russian feder number work age popul grow annual number abl bodi popul million peopl figur increas million republ tatarstan begin number abl bodi citizen reach thousand peopl purpos studi analyz determin adult live standart impact determin morbid rate survey peopl use sf intern questionnair sf health status survey major work age popul studi age age respect smallest number studi age older thus research shown live standart work age popul live larg metropoli tend signific decreas depend age gender discov high level preval medic social risk factor individu involv format determin live standart first time reveal peopl work age intens morbid depend level determin live standart data obtain make possibl develop measur improv qualiti life peopl work age reduc morbid
D011788;D006304
T078;T080
36,282,642
homeostasi tool studi technolog impact human health analysi homeostasi tool restrain save secur rehabilit technolog ensur sustain function human organ cultiv health save rehabilit technolog well health program prevent anti alcohol anti nicotin drug addict recreat activ upbring health cultur also environment medic treatment practic correct technolog cyclic mechan homeostasi describ work principl altern mode behavior social system structur generat order structur maintain order function stabil human organ relat natur dynam balanc fluctuat around certain averag valu constant deviat either direct posit strengthen chang direct negat destruct one
D013672;D006293
T090;T058;T170
36,282,641
normat legal aspect format basic prerequisit public health public review preserv public health main goal social progress develop societi search potenti opportun improv individu public health indic posit predictor increas socio econom effici societi increas healthi life expect citizen scientif review provid argument favor need profession collabor specialist various industri order univers realiz import right citizen protect public health regulatori legal document defin nation intern polici field health protect form general vector develop health care activ use sourc inform format basi studi result logic general global nation prioriti trend develop healthcar sector main prerequisit determin health save citizen adopt world communiti reflect domest document formul main prerequisit determin health defin promot activ advantag health protect creation singl prevent space specif concept respons attitud health coverag entir life cycl person sphere activ format respons attitud health motiv preserv develop inform technolog field health protect expans intersector interdisciplinari cooper order maintain strengthen health improv public health literaci transform health servic standpoint health protect develop human resourc ensur health save activ identifi determin preserv individu public health act theoret basi develop scientif practic methodolog aim solv problem improv health potenti interdisciplinari interact specialist various field activ
D011634;D003695
T058;T091;T093
36,282,640
strateg direct competit primari health care organ articl analyz current state medic servic market russian feder includ assess volum paid medic servic popul monetari expens household pay medic servic expens consolid budget russian feder healthcar invest fix asset healthcar volum pharmaceut market russia import medicin medic equip rate largest non government medic organ russia term revenu number branch cost initi admiss number patient present total revenu top non government medic organ analyz negat trend affect current state medic servic market studi risk imposit sanction opportun develop medic servic market determin measur state support health care context sanction discuss conclus present perspect develop medic servic market context sanction impos russian feder european union unit state state connect special militari oper ukrain
D009938;D008889
T092;T097
36,282,639
nation project healthcar impact export therussian medic servic articl report main direct nation project healthcar provid format medic sector hospit polyclin fit modern equip onlin servic conveni patient medic personnel staf high qualifi medic personnel author analys factor influenc develop medic tourism russian feder preserv best tradit medic practic develop togeth global trend field health preserv russian medicin becom innov order solv task set expand scope medic care foreign citizen feder project develop export medic servic implement within framework nation project healthcar alreadi unit region countri purpos work identifi factor influenc develop export russian medic servic within framework implement nation project healthcar conclus report implement project contribut inflow invest fund nation healthcar system promot russian medic center creation posit imag countri abroad
D003695;D006268
T058;T073;T093
36,282,638
methodolog approach format rate constitu entiti russian feder reflect effici qualiti medic care profil aim studi determin approach format rate constitu entiti russian feder reflect state medic care various profil effect qualiti medic care various profil studi includ comprehens analysi structur content report base result nation medic research center field event use classif group method assess advantag disadvantag use variant methodolog form subject rate russian feder use method select swot analysi methodolog publish form scientif articl base result obtain main requir build rate system subject russian feder base indic effici perform qualiti medic care formul possibl appli intern experi build benchmark system russian feder analyz requir formul build subject rate system russian feder take account peculiar domest healthcar system main methodolog approach format subject rate russian feder quantit score rate assess quantit indic without weight coeffici qualit rate assess effect medic care profil without weight coeffici mix score rate assess quantit qualit indic use weight coeffici determin expert method establish mani exist approach format subject rate russian feder base combin point rate weight coeffici establish expert method sinc differ indic differ contribut final integr valu subject rate russian feder advis conduct anoth studi establish weight coeffici indic
D003695;D005791
T058;T093
36,282,637
russian healthcar imag info field third wave covid articl contain result repeat studi russian healthcar inform field conduct third wave covid medialogia media databas well yandex search engin may septemb carri compar analysi result studi previous measur conduct decemb februari result studi part imag panel studi russian healthcar use concern structur order adjust
D000086382
T047;T067
36,282,636
sector involv public health russian feder covid pandem articl develop research agenda cross sector collabor issu public health aspect collabor scientif found covid pandem aim research studi inventori sector involv public health russian feder covid pandem put perspect import anonym survey expert health servic manag made respond ask identifi inventori sector involv public health voic opinion import covid pandem result survey compar result obtain pandem result studi suggest sector alway involv public health covid pandem without sector relat equal import howev sector inventori rank differ order import pandem without statist signific differ analys characterist featur note articl develop research agenda studi provid implic health servic manag
D058873;D000086382
T047;T067
36,282,631
lost time covid indemn claim report result wisconsin worker compens system march decemb covid pandem introduc new compens infecti diseas workplac
D014942;D000086382
T047;T064;T067
36,282,621
come hot polic transport prehospit time firearm injuri philadelphia pa polic emerg medic servic em transport patient firearm injuri prior studi evalu system lack reliabl prehospit time link polic hospit data set establish complet timelin firearm injuri outcom hypothes polic transport patient shorter prehospit time turn associ improv surviv increas unexpect survivorship hour
D005389;D014948;D004632
T061;T073;T093;T037;T058
36,282,618
support healthi breastfeed mother healthi term babi extens evid import health risk infant mother relat breastfeed world health organ recommend infant breastf exclus six month age breastfeed continu import part infant diet least two year age howev current breastfeed rate mani countri reflect recommend
D008427
T058
36,282,614
ketamin potenti treatment postpartum depress narrat review postpartum depress ppd sever debilit mood disord consequ mother children highlight need rapid act effect treatment ppd aim narrat review synthes avail literatur administr ketamin ppd propos ketamin viabl advantag treatment
D007649;D019052
T121;T048;T109
36,282,613
frequenc ill anxieti hypochondriasi proxi encount doctor parent toward children ill anxieti disord condit persist fear serious life threaten ill despit symptom current classif system assum ill anxieti experienc relat one health toward other proxi yet observ occur parent toward children studi design survey doctor common encount ill anxieti proxi iap
D006998;D010820
T097;T048
36,282,612
anxieti depress stroke evalu psychopatholog outcom stroke type use nation inpati sampl anxieti depress report complic cours stroke studi evalu associ anxieti depress independ ischem vs non ischem stroke
D002545;D020521
T047;T046
36,282,611
emot regul difficulti link trait resili symptom depress anxieti psychiatr outpati despit negat associ trait resili depress anxieti symptom mechan resili may buffer symptom remain underexplor studi investig emot regul difficulti potenti link relationship trait resili depress anxieti sever psychiatr outpati n
D010045;D000080103
T101;T041
36,282,607
random doubl blind clinic pilot trial adjunct keton supplement compar placebo treat posttraumat stress disord despit evid help role keton neuropsychiatr disord clinic trial examin agent posttraumat stress disord ptsd aim investig whether keton salt supplement improv ptsd symptom random placebo control trial
D013313
T048
36,282,606
impair insight ill unrel subject happi success life satisfact schizophrenia impair insight ill common featur schizophrenia improv insight associ better treatment adher clinic outcom time improv insight suggest increas depress symptom diminish qualiti life aim studi examin associ impair insight degre subject happi perceiv level success life satisfact patient schizophrenia spectrum disord
D012559
T048
36,282,605
telemedicin outpati treatment depress disord newli develop app tellus digit offer psychiatr outpati treatment includ diagnost therapeut tool aim studi test clinic effici patient satisfact tellus
D017216;D003866
T058;T048
36,282,604
incontin cataton sign incontin urinari fecal includ dsm criteria catatonia catatonia rate scale howev histor basi inclus consider incontin cataton sign
D002389;D005242
T184;T047;T048
36,282,584
orthoped manag patient pigment villonodular synov pigment villonodular synov pvns sometim also call tenosynovi giant cell tumor rare slow grow benign soft tissu disord pvns common affect knee associ pain hemarthrosi joint swell condit also affect hip ankl shoulder elbow articl review practic guidelin pvns diagnosi surgic nonsurg treatment
D013586;D004551
T191;T030
36,282,580
pa profess israel half decad perspect implement physician assist pas ed throughout israel began may profess show progress relat slow rate articl provid overview israel healthcar system describ implement deploy educ train scope practic pas israel plus recent develop suggest advanc profess
D010823
T097
36,282,578
assess benchmark equiti divers inclus healthcar profess healthcar profess among fastest grow career unit state issu equiti divers inclus remain challeng percentag underrepres minor group disproportion small despit mani effort increas workforc divers past sever decad demograph nation rapid chang increas racial ethnic cognit divers crucial achiev workforc capac provid access equit healthcar given grow evid divers workforc improv healthcar outcom foster uniqu perspect cognit divers help reduc health dispar urgent need address perenni barrier structur racism bias stereotyp educ institut held account integr equiti divers inclus aspect healthcar profess educ practic articl discuss potenti area innov opportun leverag assess benchmark equiti divers inclus healthcar profess abil thorough assess pa profess cultur relationship divers equiti inclus provid opportun determin well profess perform strateg plan els need done
D018864;D019985
T078;T077;T081
36,282,577
nonsurg treatment option basal cell carcinoma basal cell carcinoma bcc common form nonmelanoma skin cancer surgeri includ moh micrograph surgeri consid gold standard manag bcc yet patient may unabl undergo surgeri articl describ effect nonsurg option treat superfici bccs well nodular infiltr bccs
D002280;D012878
T191
36,282,576
prevent life alter case fluoroquinolon associ tendon fluoroquinolon ciprofloxacin levofloxacin broad spectrum antibacteri agent histor wide use urinari tract infect pneumonia intra abdomin infect associ sever serious advers reaction includ tendinopathi tendon ruptur peripher neuropathi aortic aneurysm drug use uncompl infect unless antimicrobi treatment feasibl articl describ patient experienc life alter disabl fluoroquinolon review advers reaction drug class discuss recommend treatment acut uncompl cystiti asymptomat bacteriuria
D052256;D014552;D000890
T121;T047
36,282,574
rilonacept role treat recurr pericard interleukin il antagonist rilonacept approv fda treat recurr pericard adult adolesc multipl recurr pericard compar placebo rilonacept associ lower risk recurr pericard persist clinic respons normal c reactiv protein within day higher number day minim pericard symptom patient receiv rilonacept could wean standard therapi recurr pericard eventu transit rilonacept monotherapi common advers reaction rilonacept includ inject site reaction upper respiratori tract infect increas lipid load dose rilonacept administ subcutan sq along week sq mainten dose self administ rilonacept indic treatment recurr pericard reduct risk recurr patient age year older elev c reactiv protein level signific diseas burden
D002097;D010493
T129;T047;T116
36,282,570
streptomyc solincola sp nov isol soil malaysia ureas produc gram stain posit actinobacterium design strain isol soil sampl collect highway hillslop selangor malaysia strain found produc pale yellowish pink aerial mycelia smooth long chain spore extens branch light yellowish pink substrat mycelia oatmeal agar strain grew c ph toler wv nacl optim growth occur c ph without nacl whole cell sugar hydrolys strain contain galactos glucos ribos diaminopimel acid isom detect cell wall diphosphatidylglycerol phosphatidylcholin phosphatidylethanolamin phosphatidylglycerol phosphatidylinositol found predomin polar lipid main fatti acid anteiso c iso c anteiso c iso c compar analysi rrna gene sequenc indic strain belong streptomyc famili streptomycetacea highest rrna gene sequenc similar streptomyc licheni lcr overal genom related indic reveal closest relat speci licheni lcr averag nucleotid ident digit dna dna hybrid phylogeni analys show strain close relat streptomyc fradia streptomyc lavendofolia streptomyc licheni streptomyc roseolilacinus streptomyc somaliensi base polyphas data strain repres novel speci name streptomyc solincola sp nov propos type strain tbrc dsm
D010714;D013302
T123;T007;T109
36,282,569
chelonus inanitus bracovirus encod lineag specif protein truncat immun ib like factor bracovirus ichnovirus endogen virus parasit wasp produc particl contain virul gene express host tissu necessari parasit success case bracovirus particl produc conserv gene nudivir origin integr perman wasp genom wherea virul gene strike differ depend wasp lineag date data obtain bracovirus concern speci braconid subfamili microgastrina gain broader view divers virul gene sequenc genom packag particl chelonus inanitus bracovirus cibv produc wasp belong differ subfamili chelonina egg larval parasitoid mean oviposit host egg wasp larva develop within larval stage host found cibv virul gene belong famili specif chelonina bracovirus ichnovirus howev cibv encod v ank gene encod truncat version immun cactusib factor suggest protein might play key role host parasit interact involv domest endogen virus found structur cibv v ank differ previous report phylogenet analysi support hypothesi may origin cactusib immun gene wasp genom acquir bracovirus howev evolutionari histori differ share v ank whose common origin probabl reflect horizont gene transfer event virus sequenc braconid ichneumonid wasp
D018071;D014863
T005;T204
36,282,567
judici commiss intern committe systemat prokaryot minut meet juli minut onlin meet judici commiss intern committe systemat prokaryot held juli per video confer present
D005227
T123;T168;T109
36,282,564
pseudomona lijiangensi sp nov novel phytopathogen bacterium isol black spot tobacco three gram stain negat motil amphilophotrich flagella rod shape bacteria lj lj lj isol lower leav black spot flue cure tobacco yunnan pr china result phylogenet analysi base rrna gene sequenc indic strain tobacco close relat type strain pseudomona syringa group within p fluorescen lineag lj highest sequenc ident p cichorii dsm p capsici pc p ovata f rrna gene sequenc ident lj member genus pseudomona averag nucleotid ident blast anib valu lj p cichorii dsm p capsici pc p ovata f less silico dna dna hybrid ddh valu yield formula less major fatti acid c c andor c c sum featur c c c andor c c sum featur polar lipid profil lj consist diphosphatidylglycerol phosphatidylethanolamin phosphatidylglycerol phosphatidylcholin two unidentifi phospholipid one unidentifi glycolipid predomin respiratori quinon q dna gc content lj mol basi data conclud lj repres novel speci genus pseudomona name pseudomona lijiangensi sp nov propos type strain pseudomona lijiangensi sp nov lj cctcc ab gdmcc jcm
D011549;D010714
T123;T007;T109
36,282,561
mycolicibacterium aurantiacum sp nov mycolicibacterium xanthum sp nov two novel actinobacteria isol mangrov sediment two novel actinobacteria abil degrad kerosen design b isol mangrov sediment tieshan harbour south china sea strain gram stain posit non spore form slow grow oxidas posit non motil aerob major cellular fatti acid c c c analysi rrna gene sequenc reveal close relationship strain b mycobacterium kyogaens dsm nucleotid ident strain mycolicibacterium chubuens atcc mycolicibacterium rufum js whole genom averag nucleotid blast ident ani digit dna dna hybrid dddh valu two isol type strain speci genus mycolicibacterium lower respect threshold valu ani dddh recommend bacteri speci differenti genom sequenc b compris circular mb chromosom dna gc content mol genom size mb dna gc content mol gene involv degrad aromat compound copper resist identifi genom strain could improv adapt capac mangrov environ result combin chemotaxonom analys maldi tof ms profil phenotyp analys support affili strain two novel speci within genus mycolicibacterium propos name mycolicibacterium aurantiacum sp nov b kctc mccc k mycolicibacterium xanthum sp nov kctc mccc k type strain
D039903
T007
36,282,549
pseudalkalibacillus salsugini sp nov novel salt toler bacterium isol salin lake sediment salt toler bacterium design strain egi l isol salin lake sediment xinjiang uygur autonom region pr china taxonom posit isol determin use polyphas taxonom analysi phylogenom analysi phylogenet analysi rrna gene sequenc similar indic egi l form distinct clade pseudalkalibacillus berkeleyi kctc sequenc ident novel isol could distinguish speci genus pseudalkalibacillus distinct phenotyp physiolog genotyp characterist cell egi l aerob gram stain posit non motil rod shape optim growth condit egi l occur marin agar ph c major respiratori quinon mk major fatti acid anteiso c iso c iso c anteiso c detect polar lipid includ diphosphatidylglycerol phosphatidylglycerol phosphatidylethanolamin basi genom sequenc data dna gc content egi l basi phenotyp physiolog genotyp phylogenet data strain egi l repres novel speci genus pseudalkalibacillus name pseudalkalibacillus salsugini sp nov propos type strain propos novel isol egi l kctc cgmcc
D060106;D010714
T123;T083;T070;T109
36,282,531
delay bowel necrosi due inferior mesenter arteri occlus stanford type acut aortic dissect although inferior mesenter arteri occlus due acut aortic dissect sometim occur usual consid import find herein present extrem rare case delay bowel ischaemia due inferior mesenter arteri occlus stanford type acut aortic dissect highlight need cardiac surgeon mind inferior mesenter arteri occlus patient superior mesenter arteri dissect vascular anomali mesenter arteri
D000784;D008641;D065666
T047;T046
36,282,514
zni mediat galactosyl c ether type donor convent glycosyl galactosyl donor c benzyl bn ether type function often lead anomer mixtur due anomer steric effect stabil cis tran glycosid respect herein report versatil zni direct galactosyl approach employ tether bn galactosyl donor stereoselect effici synthesi galactosid broad substrat scope reaction toler wide rang function group complex molecular architectur provid stereocontrol galactosid moder excel yield practic transform demonstr synthesi tetrasaccharid arabinogalactan fragment high stereoselect
D004986;D006027
T121;T109
36,282,505
associ person vs telehealth follow rate repeat hospit visit among patient seen emerg depart patient discharg emerg depart ed time outpati person follow associ improv mortal effect telehealth follow modal unknown
D004636;D017216
T058;T073;T093
36,282,504
associ ambient air pollut birth weight matern individu neighborhood level stressor fetal growth precis program could interrupt environment exposur specif time pregnanc insight potenti sensit window air pollut exposur associ birth weight need
D000397;D000393;D010126
T131;T103;T069;T080
36,282,503
assess cystatin c level risk stratif adult chronic kidney diseas kidney function usual estim serum creatinin level wherea altern glomerular filtrat marker cystatin c level associ close futur risk cardiovascular diseas cvd mortal
D051436;D002318
T047
36,282,502
analysi blood cultur collect laboratori process practic israel blood cultur critic diagnost procedur affect patient outcom antibiot stewardship although standard blood cultur process often measur
D016470;D018805
T047;T046
36,282,501
estim sar cov omicron ba subvari sever new england sar cov omicron subvari ba may less sever previous variant howev confound factor make interpret intrins sever challeng
D000086402;D000086382
T005;T067;T047
36,282,500
associ cardiometabol multimorbid caus coronari heart diseas mortal among black adult jackson heart studi combin diabet coronari heart diseas chd stroke multipl caus mortal risk compar individu morbid white popul lack studi black popul us
D003327;D020521;D003920
T047
36,282,499
variat clinic treatment outcom race among us veteran hospit covid patient racial ethnic minorit popul black hispan patient may less like receiv evid base covid treatment white patient contribut advers clinic outcom
D000086382;D014728
T047;T098;T067
36,282,498
menstrual cycl regular length across reproduct lifespan risk cardiovascular diseas menstrual cycl characterist may associ increas risk cardiovascular diseas cvd howev exist studi limit explor mediat role establish cvd risk factor
D002318;D003924;D006937;D006973
T047
36,282,497
variat research experi public medic school sex race ethnic divers research team critic solv complex health problem produc high qualiti medic research
D012577;D004504
T065;T073;T093
36,282,477
daili variabl urinari artifici sweeten associ oxid stress biomark urinari artifici sweeten ass prove use biomark assess dietari intak howev unclear well spot urin sampl may repres longer term exposur therefor longitudin studi design six ass two oxid stress biomark name hydroxi deoxyguanosin ohdg malondialdehyd mda determin acesulfam ace saccharin sac detect urin concentr rang loq loq ngml respect poor intrasubject variabl found measur least void requir estim particip specif mean exposur furthermor ass exhibit signific posit interact ohdg mda p hazard quotient impli safe exposur level particip ace sac best knowledg first studi sampl strategi ass urin tempor basi togeth explor potenti toxic mechan
D013549;D018384
T120;T168;T049
36,282,473
parent mental ill borderlin person disord parent behavior moder role social support parent mental disord particular borderlin person disord bpd impair parent behavior consequ children exhibit elev risk psychopatholog across lifespan social support parent thought moder relationship parent mental ill parent behavior may dampen negat effect serv start point prevent intervent paper provid literatur overview regard impact social support sequela parent mental ill bpd parent behavior
D001883;D016241
T098;T048
36,282,453
compar assess groundwat qualiti indic kannur district kerala india use multivari statist approach gis aim studi determin groundwat characterist rural industri zone kannur region groundwat data collect centr water resourc develop manag cwrdm groundwat sampl rural near industri area collect analys major anion hco co cl cation th ca mg na k fe use apha standard better understand link water qualiti paramet multivari statist analysi approach princip compon analysi pca hierarch cluster analysi hca correl matrix analysi cma pearson correl bivari one tail analysi pcbota use analys inter relationship data invers distanc weigh idw method use generat spatial distribut groundwat qualiti index gwqi water qualiti index wqi valu groundwat sampl excel good use drink purpos moder poor irrig purpos studi area excel good use drink purpos moder poor irrig purpos compar data bis standard clear groundwat kannur district good qualiti groundwat sampl pca eigen valu report statist approach studi use hca pcbota analys element result better understand groundwat qualiti develop gis base wqi map obtain utilis gain better knowledg studi area past present water qualiti status observ qualiti groundwat studi region north western portion insuffici drink water
D060766;D014874;D060587
T070;T082;T131;T081;T167
36,282,442
wake sleep metaphor normal connect intersex dsd scope review medic literatur aim studi encourag critic debat use normal medic literatur dsd intersex purpos scope review conduct identifi map various way normal use medic literatur dsd identifi studi mani case studi highlight rare case dsd other main retrospect observ studi focus improv diagnosi treatment common use adject normal associ phenotyp sex overal appear common cite criteria evalu normal sex organ studi includ also medic photograph sex organ persist use normal refer phenotyp sex worrisom given long term medic intersex bodi name normal appear lead normal life healthcar profession care ethic implic use photograph public given mani intersex person describ experi medic photographi dehuman
D019365;D012734
T078;T019;T047;T054
36,282,436
periodont diseas metabolom signatur differ biofluid systemat review periodont result complex interact genet epigenet microbi factor host respons metabolom analys reflect steadi state physiolog equilibrium cell organ well dynam metabol respons environment stimuli
D010510;D010518
T047
36,282,432
investig ocean deoxygen oxygen minimum zone central indo pacif region base hindcast dataset deoxygen increas recogn signific environment threat ocean follow sea temperatur rise due global warm climat chang consid crucial deoxygen impact import assess current status predict futur possibl ocean deoxygen instanc within central indo pacif cip region repres climat regul marin area studi divid cip five region investig deoxygen paramet dissolv oxygen temperatur salin ph collect sourc situ measur long term hindcast data overal error statist indic good accuraci hindcast data compar situ valu surfac water identifi fluctuat season pattern dissolv oxygen concentr compar water column howev fluctuat occur differ pattern region studi show ocean deoxygen acceler five region decad strongest oxygen minimum zone omz identifi bay bengal arafura sea lowest oxygen concentr less mmolm weakest omz locat south china sea mmolm concentr deoxygen rate cip region vari mmolm year depend differ control factor work five region result indic deoxygen attribut ocean warm seawat salin increas ocean acidif possibl continu futur continu global chang
D012623;D010100
T123;T196;T121;T167
36,282,427
histometr morpholog damag caus serratia marcescen tick rhipicephalus microplus acari ixodida rhipicephalus microplus tick ectoparasit caus greatest econom loss livestock industri multi resist tick increas generat ineffici tradit ixodicid biolog control propos altern work analyz histomorpholog damag caus bacteri strain ec rhipicephalus microplus ixodicid effect ec total protein evalu larval adult tick compar commerci ixodicid coumapho control femal tick process use paraffin embed techniqu stain hematoxylin eosin also pathogen ec evalu capillari feed coelom inocul test identif bacterium perform use molecular marker rna rpob pcr sequenc techniqu evolutionari distanc analyz bayesian phylogenet infer differ observ perimet area larva treat ec coumapho thick integu decreas ec treatment coumapho larva compar control group differ found adult tick capillari feed test coelom inocul ec show inhibit reproduct potenti oviposit inhibit ec strain genet relat serratia marcescen conclud bacteria caus high mortal oviposit inhibit integu thin drastic loss histoarchitectur r microplus tick larva
D048494;D026863
T204
36,282,426
cannabidiol modul nicotin receptor cannabidiol cbd import terpenoid compound marijuana psychoact effect becom great pharmaceut interest sever health condit cbd multitarget drug need establish molecular mechan cbd may exert therapeut well advers effect nicotin acetylcholin receptor nachr cation permeabl ach gate channel present nervous system non neuron cell involv differ patholog condit includ neurolog neurodegen disord inflamm cancer high resolut singl channel record confoc microscopi reveal cbd modul nachr ionotrop metabotrop function cbd lead profound concentr depend decreas nachr singl channel activ ic sub micromolar rang inhibit nachr activ take place membran pathway neither mediat receptor phosphoryl overcom posit alloster modul compat cbd stabil rest desensit nachr conform state cbd modul complex also lead later appear atyp low frequenc nachr channel open cellular level cbd inhibit increas intracellular calcium trigger nachr activ thus decreas cell calcium respons modul nachr pharmacolog relev consid evalu cbd potenti therapeut use thus studi provid novel molecular inform cbd multipl action target requir set basi prospect applic human health
D002185;D011978
T192;T121;T116;T109
36,282,407
impact repetit transcrani magnet stimul direct connect autism eeg signal pilot studi compar differ direct connect typic develop td autism spectrum disord asd children identifi potenti effect repetit transcrani magnet stimul rtms brain connect behavior children asd td children male femal averag age asd children male femal averag age particip experi asd children divid random experiment group control group experiment group receiv rtms session twice week nine week wherea control group receiv procedur sham stimul direct transfer function dtf use calcul effect connect way investig differ asd td children simultan evalu effect rtms asd result illustr dtf td children frontal lobe fp fp f f tempor lobe higher asd children frequenc band howev dtf asd children higher td midlin fz cz central lobe c c pariet lobe p p experiment group asd children effect connect decreas p fp alpha band pz gamma band stimul signific chang autism behavior checklist abc score also found social behavior effect connect deriv dtf distinguish asd td children rtms provid chang connect behavior suggest potenti use viabl treatment option asd individu
D001321;D000067877
T048
36,282,405
path plan optim unman aerial vehicl use meta heurist algorithm systemat review unman aerial vehicl uav recent increas popular various area field applic militari disast manag rescu oper public servic agricultur various area exampl result uav path plan concern determin optim path sourc destin avoid collis lower cost time energi resourc review aim assort academ studi path plan optim uav use meta heurist algorithm summar result optim algorithm extend understand current state path plan uav meta heurist optim field purpos implement broad autom search use boolean snowbal search method find academ work path plan uav studi paper distinguish follow inform obtain aggreg articl author public year journal name confer name propos algorithm aim studi outcom qualiti studi accord find meta heurist algorithm standard optim method tackl singl multi object problem besid find show meta heurist algorithm great compact path plan optim uav good progress field howev problem still exist main complex dynam environ battlefield rescu mission mobil obstacl multipl uav
D000066506;D000401
T170;T073
36,282,398
locat hygien medicin within intellectu histori hygien case e w lane r allinson nineteenth centuri hygien might confus concept one hand concept hygien gradual becom import concept focus cleanli use interchang sanit hand classic notion hygien root hippocrat teach remain influenti studi two attempt newli theoris confus concept hygien second half centuri edward w lane thoma r allinson work stand border self help medic advic theoret treatis medic philosophi exact scholar one medic thought conceptualis hygien medicin show characterist holist medic view hygien nineteenth centuri version reinterpret natur cure philosophi vital howev aim studi proper locat conceptualis hygien medicin within histor context second half nineteenth centuri rather simpli introduc medic idea book view hygien distinguish contemporari sanitari approach also similar attempt contemporari orthodox unorthodox medic doctor chronolog analysi chang concept hygien compar analysi two author medic profession view hygien paper aim help understand complic pictur nineteenth centuri hygien particular second half centuri perspect medic holism reduction
D006920;D008511
T091
36,282,373
research acut phase protein inflammatori cytokin biomark dromedari camel camelus dromedarius clinic endometr uterin diseas preval camel lead econom loss decreas fertil aim studi look express pattern acut phase protein app inflammatori cytokin dromedari camel clinic endometr ce highlight role immun pathogenesi diseas moreov identifi use paramet complementari tool ce screen well investig efficaci ceftiofur antibiot app inflammatori cytokin estim camel ce valu app hp saa fg pro inflammatori ifn tnf il il il anti inflammatori cytokin il higher camel ce healthi control p higher proport camel ce treat ceftiofur p score clinic cure first dose requir second dose conclus ce caus increas app inflammatori cytokin biomark indic signific acut phase respons diseas camel ce chang biomark could benefici understand immun pathogenesi ce dromedari camel clinic practic basic clinic research
D004716
T047
36,282,363
intrins subtyp ethiopian breast cancer patient recent develop multi gene assay gene express profil contribut signific understand clinic biolog heterogen breast cancer bc diseas pam one assay use stratifi bc patient individu treatment present studi conduct character pam base intrins subtyp among ethiopian bc patient
D001943
T191
36,282,356
immobil chromium bioavail applic organ wast indian mustard brassica juncea chromium contamin indian soil industri result product larg volum wastewat dispos becom serious problem wastewat may rang heavi metal impact soil plant health object evalu influenc farm yard manur fym pressmud pm applic indian mustard growth chromium cr uptak tanneri effluent irrig cr contamin soil soil collect tanneri effluent irrig field chromium contamin shekhpura villag kanpur india pot cultur experi carri grow indian mustard brassica juncea var rh cr contamin soil applic differ level combin fym pm g kg biomass yield cr uptak bioconcentr factor bcf transfer factor tf transfer effici te cr remov indic examin higher dose fym pm result reduct cr concentr shoot g g root g g absorpt plant tissu improv total dri matter yield g pot use fym pm substanti p impact phytoremedi paramet like bcf te cr remov combin applic fym g kg pm g kg enhanc dri matter yield shoot g pot root g pot reduc cr uptak mg pot individu amend addit fym mg pot pm mg pot combin applic fym g kg pm g kg could benefici remedi cr contamin area cultiv crop
D012989;D019216
T131;T196
36,282,355
human respiratori rate rest schoolchildren know often breath even expert nt know exact aim public develop model rest spontan breath rate use physiolog physic mathemat method aid principl evolut push physiolog direct econom possibl respiratori rate follow equat paramet formula see text product rate organ resist static complianc dead space lung inspir durat expir durat ratio end expiratori formula see text fraction deriv requir exclus secondari school mathemat use exampl adult human newborn child data literatur result normal valu breath rate rest reason higher respiratori rate newborn human compar adult relat high formula see text product rate togeth compar low complianc lung side result fact common alveolar pressur throughout lung common time constant consequ econom principl well sinc paramet human specif reason assum equat could also applic mani anim breath lung within thorax especi mammal physiolog biolog also medicin could benefit applic discuss pulmonari function diagnost includ pathophysiolog howev present public claim theoret concept spontan quiet breath rate absenc compar anim data public intend encourag scientif test
D056152;D008168
T201;T023
36,282,353
function genom enabl character cypb cypb plumbago zeylanica l substanti involv plumbagin biosynthesi novel cytochrom ps cypb cypb plumbago zeylanica function character understand involv polyketid plumbagin biosynthesi propos methyl naphthalenediol isoshinanolon intermedi plumbagin biosynthesi plumbago zeylanica l p zeylanica medicin import plant belong famili plumbaginacea compris abund naphthoquinon plumbagin anti cancer activ polyketid synthas pks enzym identifi biosynthet pathway catalyz iter condens acetyl coa malonyl coa molecul plumbagin biosynthesi involv hydroxyl oxid hydrat dehydr intermedi compound expect catalyz cytochrom ps cyp identifi cyp co express analysi carri use pks candid gene eight identifi cyp cypb cypb similar express pks belong cyp famili phylogenet analysi suggest cypb cypb cluster cyp cypb cypd cype cypaa subfamili known involv hydroxyl oxid reaction moreov artifici microrna mediat transient individu silenc co silenc cypb cypb signific reduc plumbagin increas methyl naphthalenediol isoshinanolon content base metabolit analysi propos methyl naphthalenediol isoshinanolon function intermedi plumbagin biosynthesi transient silenc express dock analysi reveal cypb involv c oxid c hydroxyl c c hydrat methyl naphthalenediol form isoshinanolon wherea cypb catalyz c c dehydr c oxid isoshinanolon form plumbagin result indic cypb cypb promiscu necessari plumbagin biosynthesi first report identif function character p zeylanica specif cyp involv plumbagin biosynthet pathway general hexaketid synthesi plant
D029606;D009285;D061065;D035683
T121;T123;T109;T114;T002