PMID
int64 35.7M
36.4M
| Title/Abstract
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36,269,709
|
model optimis approach laser cut sheet simultan appli ev compon product paper propos laser cut potenti viabl altern stamp mass manufactur thin steel compon stator rotor compon electr automot sector current laser cut process much less effici stamp howev laser cut much flexibl use small batch one product paper assess potenti perform laser cut oper multipl sheet layer simultan method refer herein polystromata cut numer model use assess manufactur perform stamp tradit laser cut polystromata laser cut polystromata laser cut shown capabl produc part less cost stamp howev polystromata remain slower stamp take time produc stator stack research identifi optimis polystromata process complex perform effici vari wild depend manufactur set work aim provid best practic optimis methodolog polystromata laser cut assess result use differ manufactur object
|
D007834;D053685
|
T061;T074;T073
|
36,269,708
|
genom wide discoveri diabet depend triglycerid associ loci aim discov loci associ triglycerid tg level context type diabet td conduct genom wide associ studi gwas genotyp particip uk biobank ukb td status tg level
|
D003922;D003924;D014280
|
T123;T047;T109
|
36,269,706
|
oral tradit chines patent medicin combin non steroid anti inflammatori drug primari dysmenorrhea protocol bayesian network meta analysi systemat review primari dysmenorrhea pd common gynecolog disord increas high preval worldwid pd often accompani dysmenorrhea associ symptom trigger exacerb even caus depress anxieti patient effect first line medic non steroid anti inflammatori drug nsaid becom widespread across china combin oral tradit chines patent medicin tcpms pd clinic practic hope provid better efficaci safeti evid oral tcpms combin nsaid oral tcpmsnsaid patient pd network meta analysi
|
D000894;D004365;D004412
|
T121;T047;T123
|
36,269,702
|
sex determin diseas sever clinic outcom febril children five present region referr hospit uganda sex gender well establish determin health adult adolesc popul low resourc set limit data sex determin host respons diseas clinic outcom febril children sub saharan africa risk infect relat mortal greatest examin sex differ gender bias health seek behavior clinic care biolog respons infect outcom prospect observ cohort febril children year age present region referr hospit jinja uganda main outcom stratifi sex diseas sever present measur clinic biolog paramet clinic manag eg time see physician treatment diagnosi diseas outcom eg mortal clinic measur diseas sever includ lambarn organ dysfunct score lod sign inflamm children kill sick pediatr earli death index africa pedia biolog measur diseas sever assess use circul marker immun endotheli activ associ sever fatal infect differ outcom sex analyz use bivari analys bonferroni correct multipl comparison cohort febril patient admit hospit n malaria infect common children present sever diseas lod score children die death n occur within hour hospit admiss clinic measur diseas sever present clinic manag outcom eg mortal differ sex children five year age host respons infect determin endotheli inflammatori mediat eg strem ang quantifi hospit present differ sex cohort children age five sex princip determin diseas sever hospit present clinic manag diseas outcom biolog respons infect p valu signific comparison bonferroni correct result suggest health seek behavior caregiv clinic care hospit set reflect gender bias cohort
|
D063507;D005334
|
T184;T054
|
36,269,701
|
preval probabl characterist malaria filariasi co infect systemat review meta analysi malaria filariasi signific vector born diseas co endem human popul studi aim collat evid probabl characterist malaria filariasi co infect particip among studi report co occurr diseas
|
D060085;D005368;D008368;D008288
|
T047
|
36,269,700
|
ocular find surgeri detail outcom prolif diabet retinopathi patient chronic kidney diseas investig influenc impair renal function fundus characterist par plana vitrectomi ppv detail outcom patient prolif diabet retinopathi pdr
|
D003930;D051436;D003920
|
T047
|
36,269,699
|
capabl perspect sustain employ dutch focus group studi organiz work person convers factor field work shift toward valu base approach studi sustain employ present day worker capabl approach offer valu base innov conceptualis framework sustain employ character contextu normat divers capabl dutch employe establish valid yet known convers factor person work organiz level enabl employe achiev valu work differ dutch occup sector
|
D004651;D009790
|
T090;T098;T080;T033;T057
|
36,269,698
|
rule base habitat suitabl model reintroduct grey wolf cani lupus scotland though nativ scotland grey wolf cani lupus extirp c year ago part global erad drive global popul recent expand occupi former rang evid grow apex predat provid rang ecolog benefit stem reduct overgraz deer someth scotland suffer studi build rule base habitat suitabl model wolv scottish mainland exist literatur identifi import variabl land cover prey densiti road densiti human densiti establish threshold suitabl fuzzi membership function use assign suitabl valu variabl follow fuzzi overlay combin four novel approach habitat suitabl model terrestri mammal model sensit test land cover prey densiti variabl constitut knowledg gap incomplet dataset respect highland grampian mountain emerg strong consist suitabl area larg due high negat covari prey densiti roadhuman densiti sensit test reveal model fair robust chang prey densiti less robust chang score land cover latter alter distribut land main suitabl rang howev statist signific test least generous version model emerg give signific differ result depend version model contigu area km km shown suitabl could suffici support pack four wolv averag pack rang size taken km conclud term habitat avail reintroduct feasibl
|
D019596;D003670
|
T015
|
36,269,696
|
clinic characterist outcom sar cov b infect hospit patient multi surg comparison louisiana peer review data describ sar cov omicron variant symptom clinic outcom compar prior surg unit state thus far limit sought determin diseas sever present featur epidemiolog factor sar cov omicron variant compar prior surg
|
D000086382
|
T047;T067
|
36,269,692
|
updat oral clinic cours among patient sever acut respiratori syndrom coronavirus sar cov infect clinic follow prospect preval cohort studi contemporari literatur reveal sever acut respiratori syndrom coronavirus sar cov caus acut sialaden relat symptom discomfort pain swell secretori dysfunct salivari gland secretori dysfunct due sar cov infect induc xerostomia associ clinic cours sore tongu mucos ulcer gingiv oral caviti furthermor report covid caus develop oral manifest
|
D000086382;D014987;D005891
|
T047;T067
|
36,269,683
|
congenit superior sternal cleft isol newborn report rare case literatur review background sternal cleft great rare congenit thorac deform aris failur sternal bar fusion process complet fetal period incid less case report herein present case report newborn girl superior congenit sternal cleft babi born scar like tissu found middl chest extend root umbil cord base imag data newborn diagnos sternal cleft belong superior sternal cleft associ congenit deform conclus rare congenit thorac deform postpartum diagnosi sternal cleft main current base medic imag includ thorac comput tomographi ct three dimension reconstruct ct magnet reson imag mri sternum cleft affect aesthet appear also lead destruct bone structur thorax result oppos thorac movement therefor earli diagnosi earli treatment play signific role treatment congenit sternal deform regardless whether clinic symptom sternal cleft primari repair surgeri must done soon possibl neonat period best simpl surgic techniqu achiev remark effect
|
D013249;D009139
|
T019;T023
|
36,269,669
|
comprehens imag review pleural fistula diagnosi manag pleural fistula abnorm communic pleural caviti adjac structur interplay anatom physiolog factor includ proxim various intrathorac structur deep pleural recess negat pleural pressur make pleura easi victim fistul iatrogen creation follow necrot infect malign common caus overal incid size postsurg pleural fistula decreas increas adopt vascular flap high risk resect smaller fistula develop set post radiat therapi chang necrot infect immunosuppress patient use newer antiangiogen chemotherapi challeng visual direct imag sign clinic practic often subtl indirect multimod imag biochem pleural fluid analysi offer import adjunct inform diagnosi suggest first imag studi certain pleural fistula inconsequenti spontan close without divers flow use posit pressur ventil other carri higher risk complic recurr estim fistula size factor impair heal possibl divers import consider decid endoscop surgic closur author tailor articl general imag clinic practition review type pleural fistula rang routin rare regard etiolog pathophysiolog clinic cue imag featur nuanc pleural fluid analysi manag option avail today rsna
|
D010995;D005402
|
T047;T190
|
36,269,668
|
qualiti improv report safeti program prevent central line associ bloodstream infect increas usag peripher insert central cathet picc medic imag depart led correspond increas case central line associ bloodstream infect clabsi howev condit prevent proper monitor use asept techniqu comprehens unit base safeti program cusp qualiti improv qi measur implement health care institut reduc incid clabsi howev effect strategi yet establish author describ qi project evalu implement cusp teach hospit reduc picc associ bloodstream infect bsi framework consist five step process understand train staff scienc safeti assembl team engag senior execut identifi defect sensemak implement teamwork communic strategi seri relat sequenti step use qi tool target identifi improv exist process workflow reengin nine month start cusp intervent picc associ bsi incid hospit reduc per central line day intervent incid bsi also reduc correspond qi process studi may adopt hospit involv minim cost signific impact patient safeti well qi sequenti step describ captur implement process modifi use depart set patient safeti could compromis onlin supplement materi avail articl rsna
|
D055499;D002405;D018805
|
T061;T047;T046
|
36,269,664
|
general health status indic digit inequ moder effect age educ cross section studi consider effort direct offer onlin health inform servic aim general popul effort potenti support peopl obtain improv health outcom howev health inform servic move onlin issu equal need consid studi focus general popul take point departur health status physic function social function mental health perceiv health physic pain link internet access span internet attitud materi access internet skill health relat internet use
|
D020407;D006304
|
T170;T073;T080
|
36,269,661
|
perform safeti sodium hyaluron tear substitut polyethylen glycol dri eye diseas multicent investig mask random noninferior trial purpos compar perform safeti tear substitut contain sodium hyaluron sh one contain sh polyethylen glycol peg contain sh method multicent random investig mask noninferior trial patient moder sever dri eye diseas underw week washout random assign receiv sh plus peg tear substitut n compar sh tear substitut n time daili month primari perform endpoint chang baselin ocular surfac fluorescein stain osf score day per protocol pp popul accord point oxford scheme noninferior margin result group improv signific term sign symptom among patient without major protocol deviat pp popul osf score decreas day baselin sh plus peg group compar group confid interv differ demonstr noninferior day improv osf score signific greater sh plus peg group p safeti profil satisfactori group conclus sh plus peg tear substitut noninferior sh tear substitut studi popul may provid addit benefit long term clinicaltrialsgov id nct
|
D006820;D015352
|
T123;T121;T184;T109;T122;T047
|
36,269,659
|
measur properti smartphon approach assess physic activ healthi young peopl systemat review physic inact prevent risk factor sever chronic diseas one drive forc behind grow global burden diseas recent evid shown intervent use mobil smartphon app promot signific increas physic activ pa level howev accuraci reliabl use app unknown
|
D000068997;D063731
|
T170;T073
|
36,269,652
|
ocular biodistribut daili bilastin eye drop reveal highest level conjunctiva h postadministr purpos bilastin second generat antihistamin shown effect treatment allerg conjunct object studi evalu pharmacokinet pks biodistribut bilastin preserv free eye drop method bilastin quantifi conjunctiva cornea aqueous humor vitreous humor irisciliari bodi retinachoroid crystallin len plasma follow singl topic administr male dutch belt rabbit result concentr bilastin highest conjunctiva c max ngg h postadministr area concentr time curv auc nghg cornea c max ngg h postadministr auc nghg follow irisciliari bodi retinachoroid aqueous humor plasma vitreous humor crystallin len quantifi bilastin concentr observ h instil conjunctiva ngg cornea ngg irisciliari bodi ngg retinachoroid ngg crystallin len ngg plasma aqueous humor vitreous humor bilastin detect h postadministr ngml ngml ngg respect conclus pks biodistribut bilastin eye drop rabbit reveal mark preferenti distribut conjunctiva target tissu sustain level h find consist clinic efficaci trial support daili administr topic bilastin treatment allerg conjunct
|
D003233
|
T047
|
36,269,639
|
ration design synthesi biolog evalu novel spr antagonist revers fu resist colorect cancer resist fu reduc clinic efficaci treatment colorect cancer sphingosin phosphat receptor spr emerg potenti target revers fu resist inhibit express dihydropyrimidin dehydrogenas dpd studi novel spr antagonist base aryl urea structur design synthes structur activ relationship investig base spr bind assay repres compound potent interact spr k valu nm display potent fu resensit activ multipl fu resist tumor cell line particular sw fu ec show cytotox normal colon cell line ncm moreov signific enhanc antitumor efficaci fu sw fu anim model data suggest could novel lead compound develop fu resensit agent
|
D005472;D015179
|
T121;T191;T114;T109
|
36,269,633
|
bacteremia trauma contemporari analysi blood cultur result outcom patient background bacteremia potenti lethal complic limit research exist describ incid associ outcom trauma patient descript studi character incid risk factor outcom bacteremia trauma patient method studi use system wide trauma registryelectron data warehous select trauma activ age year blood cultur inform includ pathogen genera speci obtain electron laboratori record bacteremia posit defin two blood cultur within two hour grow organ bacteremia negat growth one blood cultur growth growth two differ organ bacteremia posit bacteremia negat patient compar patient without blood cultur logist regress compar blood cultur result outcom adjust age gender injuri sever score iss comorbid result patient center blood cultur blood cultur bacteremia posit compar blood cultur bacteremia posit patient like male higher iss comorbid intens care unit use bacteremia posit patient like die adjust odd ratio aor confid interv ci p sever sepsissept shock aor ci p common isol staphylococcus epidermidi non methicillin resist staphylococcus aureus escherichia coli highest mortal associ pseudomona aeruginosa enterococcus faecali escherichia coli conclus bacteremia trauma uncommon associ increas resourc use poorer outcom bacteremia suspicion thereof identifi high risk popul justifi aggress empir intervent maxim surviv
|
D055624;D016470;D018805
|
T047;T007;T046
|
36,269,622
|
triazol methanaminium pillar aren function singl nanochannel quantit analysi pyrophosph water inorgan pyrophosph ppi import biolog function anion play crucial role life scienc environment scienc medicin chemic process quantif ppi water far reach signific life explor diseas diagnosi water pollut control label free quantit detect ppi anion nanofluid sens devic base conic singl nanochannel demonstr channel surfac function synthet ppi receptor triazol methanaminium function pillar aren tamap use carbodiimid coupl chemistri due specif bind tamap ppi function nanochannel discrimin ppi inorgan anion high select ionic current record even presenc various interf anion current respons exhibit linear correl ppi concentr rang limit detect spike recoveri analysi ppi east lake water sampl indic propos nanofluid sensor abil quantit micromolar concentr ppi environment water sampl
|
D011756;D014867
|
T121;T197
|
36,269,621
|
fibrinogen reliabl biomark diagnosi peri prosthet joint infect systemat review meta analysi background recent year sever studi identifi close correl coagul cascad inflammatori mechan infect diseas fibrinogen pf emerg promis biomark diagnosi peri prosthet joint infect pji studi aim investig diagnost valu pf diagnos pji explor potenti caus influenc diagnost valu pf materi method pubm embas cochran librari search regard role fibrinogen biomark diagnosi pji studi english includ meta analysi determin diagnost valu fibrinogen pji detect hip knee arthroplasti appli recogn diagnost criteria pji qualiti evalu studi includ perform pool sensit specif likelihood ratio diagnost odd ratio dor area receiv oper characterist curv auroc obtain use statist softwar stata version statacorp colleg station tx result ten studi retrospect includ studi low public bias detect high heterogen among plasma fibrinogen show good diagnost accuraci clinic util pji sensit confid interv ci specif ci auroc ci dor ci conclus attempt find ideal biomark crucial improv sensit specif current diagnost algorithm pji analysi perform current studi indic plasma fibrinogen test valid biomark pji diagnosi
|
D016459;D001170;D006490
|
T121;T047;T046
|
36,269,615
|
circrna profil reveal abund circbdp regul bovin fat develop spong mir bmir target sirttrarg prolifer differenti preadipocyt import factor determin bovin fat develop close relat feed convers ratio carcass trait beef qualiti purpos studi identifi effect candid circrna mirna prolifer differenti bovin preadipocyt order provid basic materi molecular breed cattl circrna sequenc perform bovin adipocyt sampl differ differenti time point total differenti express circrna identifi among circbdp deriv bovin bdp gene potenti bind site mir known regul bovin fat develop mir b give us hint circbdp may regul bovin fat develop adsorb mir mir b result reveal circbdp overexpress promot prolifer differenti bovin preadipocyt mirna profil bovin adipocyt differ differenti time point also analyz use small rna sequenc method total differenti express mirna identifi includ mir mir b expect dual luciferas report result show circbdp competit adsorb mir b mir overexpress interfer mir b bovin preadipocyt l show mir b promot prolifer differenti preadipocyt result display mir b mir simultan target sirt gene mir also target utr region trarg gene summari studi found mir b mir involv fat develop target sirt trarg result studi lay foundat research fat develop beef cattl industri
|
D000079962;D035683
|
T123;T114
|
36,269,603
|
assess facial injuri slock incarcer patient slock padlock sock use weapon correct facil induc trauma assess examin preval pattern degre slock padlock induc facial fractur qualiti assess initi perform retrospect analysi incarcer patient treat surgic facial fractur academ medic center fifti seven patient describ injuri padlock specifi slock preval padlock induc facial fractur doubl padlock induc facial fractur determin complex fist p find support reduc facial trauma louisiana correct facil remov access padlock
|
D005151;D012887;D011329
|
T098;T037
|
36,269,602
|
femal opioid court particip narrat silo medic legal social servic sector interact inform futur integr intervent gap exist regard design gender specif intervent women charg opioid use disord oud relat crime nation recent effort includ opioid court treatment court present opportun earlier intervent women judici supervis interview femal particip first known opioid court could inform cross sector integr approach address need data reveal complex particip involv myriad cross sector organ given dualiti role simultan lifetim victim oud relat perpetr particip difficulti trust system intend help due systemat failur prevent address abus neglect lifetim opioid crisi solv without understand earli miss intervent opportun cross sector approach
|
D000701;D009293
|
T121;T048;T131;T109
|
36,269,595
|
antidepress hip knee osteoarthr although pain common osteoarthr peopl fail achiev adequ analgesia increas acknowledg contribut pain sensitis result investig medic affect pain process central effect antidepress contribut pain manag condit pain sensitis present
|
D015207;D020370
|
T047
|
36,269,593
|
parvovirus b associ sever anemia adult liver transplant recipi case seri review literatur background parvovirus b bv infect rare caus sever anemia liver transplant recipi howev studi systemat review report case summar experi manag diseas object describ retrospect case seri eight adult liver transplant recipi bv associ sever anemia perform literatur review epidemiolog etiolog clinic cours diagnosi treatment option avail outcom bv associ anemia adult liver transplant recipi patient method systemat review articl describ adult liver transplant recipi bv associ anemia pubm sciencedirect databas databas incept may result eight articl contain case identifi addit eight case center total patient mean age year male eighti seven percent develop transfus depend anemia within two month liver transplant lt fever progress anemia among major manifest intraven immunoglobulin ivig base therapi given patient treatment protocol vari among differ center except two case die comorbid patient obtain long term recoveri anemia one cours treatment six experienc relaps revers repeat cours ivig therapi two recipi present ivig associ side effect two develop acut cellular reject acr reduct immunosuppress conclus bv infect suspect earli caus sever anemia unknown etiolog adult liver transplant recipi clearanc bv typic lag behind recoveri anemia inadequ clearanc virus cessat ivig appear potenti risk anemia recurr moreov attent paid side effect high dose ivig infus acr reduct immunosuppress
|
D016732;D010322;D016031;D000740
|
T061;T005;T047
|
36,269,584
|
particip educ employ train neet hope mitig new social risk uk young peopl particip educ employ train neet key polici concern europ studi bring forward idea hope form life cours agenc examin whether hope think play protect role risk neet context british welfar state hope conceptualis multidimension tempor embed agent mental compris one sens adapt decis make present pathway think toward futur longitudin estim base latest understand societi microdata indic direct associ higher hope mode averag lower likelihood neet interact model assess whether hope agenc moder experi parent workless find indic hope agenc shown import face neet risk born famili background uk build ensur young peopl maintain adapt agent mental toward futur educ employ long term may prove one cost effect polici approach
|
D004651
|
T033;T098;T080
|
36,269,582
|
anatom doubl bundl anterior cruciat ligament reconstruct superior anatom singl bundl reconstruct year follow random clinic trial anatom doubl bundl db techniqu purport superior techniqu due mimick doubl strand anatom format anterior cruciat ligament acl previous studi year follow conflict whether techniqu superior previous gold standard method acl reconstruct anatom singl bundl sb reconstruct
|
D059549;D007593;D010003
|
T061;T033;T047
|
36,269,580
|
psychroflexus curvus sp nov psychroflexus longus sp nov psychroflexus montanilacus sp nov isol salt lake tibetan plateau four gram stain negat catalas oxidas posit rod shape non motil strain cakw cakw cakw cclw isol salt lake china comparison base rrna gene sequenc show four strain show less similar speci genus psychroflexus phylogenet tree reconstruct base rrna gene sequenc also show psychroflexus speci close relat neighbour four strain sequenc draft genom size strain cakw cakw cakw cclw mbp gc content respect phylogenom tree reconstruct base ubcg getphylomark pipelin demonstr four strain belong genus psychroflexus calcul pairwis ortholog averag nucleotid ident base usearch digit dna dna hybrid averag amino acid sequenc ident valu among strain cakw cakw cakw cclw speci genus psychroflexus equal lower valu strain cakw cakw respect respiratori quinon four strain mk major fatti acid iso c c c iso c anteiso c major polar lipid four strain includ phosphatidylethanolamin unidentifi aminolipid two kind unidentifi lipid strain cclw contain diphosphatidylglycerol base descript strain cakw cakw cakw cclw belong genus psychroflexus repres three independ novel speci name psychroflexus curvus sp nov type strain cakw gdmcc kctc psychroflexus longus sp nov type strain cakw gdmcc kctc psychroflexus montanilacus sp nov type strain cclw gdmcc kctc propos
|
D041965;D060106
|
T083;T007;T070
|
36,269,578
|
vibrio ostrea sp nov novel gut bacterium isol yellow sea oyster gram stain negat oxidas catalas posit facult anaerob motil bacterium design strain og isol gut oyster collect yellow sea republ korea strain grew c ph wv nacl phylogenet analysi base rrna gene sequenc reveal strain og affili genus vibrio highest sequenc similar vibrio coralliilyticus atcc baa follow vibrio variabili r vibrio hepatarius lmg vibrio neptunius lmg relat vibrio tritonius jcm vibrio fluviali nbrc vibrio furnissii cip complet genom strain og compris two chromosom total bp gc content result analysi base whole genom sequenc show distinct strain og averag nucleotid ident ani valu strain og closest strain v coralliilyticus atcc baa v variabili r v hepatarius lmg v neptunius kctc v tritonius jcm v fluviali atcc v furnissi cip respect digit dna dna hybrid valu strain og close relat strain respect major fatti acid strain og sum featur c c andor c c sum featur c c andor c c c polar lipid contain phosphatidylethanolamin phosphatidylglycerol diphosphatidylglycerol strain og contain q quinon basi polyphas taxonom characterist strain og consid repres novel speci name vibrio ostrea sp nov propos type strain og kctc gdmcc
|
D010125;D014733
|
T007;T204
|
36,269,574
|
novel speci lactic acid bacteria ligilactobacillus pabuli sp nov isol alfalfa silag studi isol novel strain lactic acid bacteria af alfalfa silag prepar local morioka iwat japan polyphas taxonomi use character bacteri strain bacterium rod shape gram stain posit non spore form catalas negat strain grew various temperatur c ph level optimum growth condit temperatur c ph af exhibit growth salt nacl concentr wv gc content strain genom dna major fatti acid c c c c cyclo c sum featur rrna gene sequenc reveal af repres member genus ligilactobacillus higher sequenc similar ligilactobacillus pobuzihii ligilactobacillus acidipisci ligilactobacillus salitoleran digit dna dna hybrid valu af phylogenet relat speci genus ligilactobacillus rang averag nucleotid ident strain close relat taxa lower threshold use speci differenti light mention physiolog genotyp chemotaxonom phylogenet evid confirm af repres member genus ligilactobacillus constitut novel speci propos name ligilactobacillus pabuli sp nov speci type strain af maff jcm bcrc
|
D012820;D056546
|
T168;T007
|
36,269,568
|
sulfurimona marina sp nov oblig chemolithoautotroph sulphur oxid bacterium isol deep sea sediment sampl south china sea novel marin bacterium design strain b isol deep sea sediment sampl collect south china sea cell observ gram stain negat motil rod shape singl polar flagellum b could grow c optimum c ph optimum ph presenc wv nacl optimum isol grew chemolithoautotroph sulphid element sulphur thiosulph electron donor carbon dioxid sole carbon sourc molecular oxygen sole electron acceptor molecular hydrogen support growth predomin fatti acid b c c c c c result phylogenet analysi base rrna gene sequenc indic b repres member genus sulfurimona highest similar rrna gene sequenc sulfurimona indica nwn sulfurimona crateri sn sulfurimona xiamenensi n sulfurimona paralvinella go sequenc similar member genus sulfurimona less addit averag nucleotid ident ani valu digit dna dna hybrid dddh estim b indica nwn respect size complet genom b bp dna gc content mol basi phenotyp phylogenet genom data present strain b repres novel speci genus sulfurimona name sulfurimona marina sp nov propos type strain b mccc kctc
|
D012623;D013885
|
T197;T167
|
36,269,567
|
reclassif clostridium aurantibutyricum helling clostridium roseum ex mccoy mcclung cato et al clostridium aurantibutyricum clostridium felsineum clostridium roseum share high similar base multi locus sequenc analysi studi correct taxonom status determin use genom phenotyp investig averag nucleotid ident base mummer align genom silico dna dna hybrid result valu respect strong indic strain member speci addit morpholog investig fatti acid analys substrat util test reveal strike differ strain therefor propos reclassif c aurantibutyricum c roseum later heterotyp synonym c felsineum type strain lodg sever cultur collect atcc dsm ncimb
|
D005227;D009711
|
T123;T168;T114;T109
|
36,269,566
|
gordonia zhenghanii sp nov gordonia liuliyunia sp nov isol bat faec four mesophil actinobacteria hy hy hy hy isol faec bat collect southern china found strict aerob non motil rod shape oxidas negat gram stain posit catalas posit strain hy hy contain meso diaminopimel acid diagnost diamino acid mk h sole respiratori quinon arabinos galactos ribos detect whole cell hydrolys type strain main cellular fatti acid strain c c c methyl c sum featur strain hy hy contain diphosphatidylglycerol phosphatidylethanolamin phosphatidylinositol phosphatidyl inositol mannosid major polar lipid phylogeneticphylogenom analys base rrna gene genom sequenc comparison reveal four strain belong genus gordonia close relat g neofelifaeci nrrl b sequenc similar ezbiocloud databas gc content strain hy hy base genom dna respect dna dna related valu two type strain member genus gordonia far genotyp phenotyp data indic four strain repres two novel separ speci name gordonia zhenghanii sp nov gordonia liuliyunia sp nov propos hy cgmcc jcm hy cgmcc jcm respect type strain
|
D002685
|
T015
|
36,269,565
|
limibaculum sedimini sp nov isol mangrov sediment gram stain negat cream colour aerob motil ovoid rod shape bacterium design ft isol mangrov sediment collect shenzhen pr china taxonom posit strain ft establish phylogenet physiolog biochem chemotaxonom analys strain ft grew optim c ph presenc wv nacl result rrna gene sequenc analysi show strain ft similar relat limibaculum halophilum cau phaeovulum vinaykumarii dsm amaricoccus solimangrovi hb major fatti acid c c methyl c c sole respiratori quinon q polar lipid phosphatidylglycerol one unidentifi glycolipid three unidentifi aminolipid three unidentifi phospholipid estim genom size bp genom dna gc content mol base distinct phenotyp chemotaxonom phylogenet characterist strain ft repres novel speci genus limibaculum name limibaculum sedimini sp nov propos mccc k kctc
|
D012965;D005227
|
T121;T123;T109;T168;T196;T197;T130
|
36,269,563
|
machin learn model identifi new inhibitor human oatpb uptak transport oatpb slcb larg local sinusoid membran hepatocyt known victim unwant drug drug interact comput model use identifi potenti substrat andor inhibitor clinic relev transport goal generat oatpb vitro inhibit data h estron sulfat es transport cho cell use build machin learn model facilit comparison seven differ classif model deep learn adaboost decis tree bernoulli nave bay k nearest neighbor knn random forest support vector classifi svc logist regress lreg xgboost xgb use ecfp fingerprint perform fold nest cross valid addit compar model use pharmacophor simpl chemic descriptor alon plus ecfp well ecfp ecfp fingerprint sever machin learn algorithm svc lreg xgb knn excel nest cross valid statist particular accuraci auc specif extern test set contain uniqu compound train set demonstr everi threshold svc outperform algorithm base rank normal score prospect valid test set chosen use predict score svc model ecfp fingerprint test vitro compound accuraci predict activ inhibit show inhibit compound six abamectin asiaticosid berbamin doramectin mobocertinib umbralisib appear novel inhibitor oatpb previous report valid machin learn model use make predict drug drug interact human oatpb alongsid machin learn model import drug transport megatran softwar
|
D000069550;D000465
|
T170;T066
|
36,269,562
|
topic corticosteroid dri eye dri eye diseas ded aris various etiolog factor lead tear film instabl ocular surfac damag neurosensori chang ded caus symptom ocular dryness burn itch pain visual impair given well establish anti inflammatori effect topic steroid prepar wide use short term treatment option ded potenti risk ocular hypertens cataract infect associ long term use topic steroid publish trial compar efficaci safeti topic steroid versus placebo most short durat three eight week
|
D015352;D005938
|
T039;T184;T109;T125;T047
|
36,269,561
|
bromin sulfur contain angucyclin deriv singl pathway identif nocardiopsistin f one novel bromin nocardiopsistin two new sulfur contain nocardiopsistin e f identifi nocardiopsi sp hb j biosynthet gene cluster ncd featur brominas identifi compound exhibit signific anti methicillin resist staphylococcus aureus anti mrsa activ minimum inhibitori concentr mic gml respect singl bromin drastic enhanc anti mrsa activ fold without alter cell toxic acquir new activ bacteri pathogen vancomycin resist aureus vrsa enterococcus faecium bacillus cereus
|
D055624
|
T007
|
36,269,540
|
updat diagnost laboratori biomark multipl sclerosi mani patient multipl sclerosi ms diagnost process lengthi cost fraught error recent research aim address unmet need accur simpl diagnost process discoveri novel diagnost biomark review summar recent studi ms diagnost fluid biomark focus blood biomark includ discuss technic limit practic applic
|
D009103
|
T047
|
36,269,539
|
vascular consider amyloid immunotherapi amyloid beta plaqu accumul hallmark patholog contribut alzheim diseas ad wide hypothes lead cognit declin decad research anti immunotherapi provid evid increas clearanc brain howev frequent accompani complic vascular deficit articl review histori anti immunotherapi clinic find provid recommend move forward
|
D016229;D000544
|
T047;T116;T048
|
36,269,526
|
use supervis machin learn model predict oncotyp dx risk categori node posit patient older year age use oncotyp dx recurr score rs predict chemotherapi benefit patient hormon receptor positiveh negat hrher breast cancer recent expand includ postmenopaus patient n diseas rs avail limit resourc poor set howev prompt develop statist model predict rs use clinicopatholog featur sought assess perform supervis machin learn model cohort patient year age n diseas
|
D011960;D001943
|
T191;T116;T192
|
36,269,490
|
batesonian mendel pearsonian biometri shed new light controversi william bateson karl pearson paper contribut ongo reassess controversi william bateson karl pearson characteris call batesonian mendel pearsonian biometri coher compet scientif outlook contrari thesi controversi stem diverg theoret commit natur hered evolut argu pearson bateson altern view process ultim reli differ apprais methodolog valu statist apparatus develop franci galton accord contend bateson belief primaci cross breed experi statist analysi constitut minim methodolog unifi condit ensur intern coher batesonian mendel moreov belief impli view studi hered evolut experiment endeavour concept hered evolut fundament discontinu process similar identifi minim methodolog unifi condit pearsonian biometri characteris view experiment method subordin statist analysi accord methodolog standard set biometr research methodolog commit entail conceiv studi hered evolut subsum biometri prime pearson regard discontinu hereditari evolutionari process except statist norm final conclud batesonian mendel pearsonian biometri repres two potenti version singl genet base evolutionari synthesi sinc methodolog principl phenomena play central role former also acknowledg latter albeit fring case convers
|
D040941;D005823
|
T091;T044
|
36,269,471
|
risk factor associ bovin subclin mastiti amazon micro region studi evalu main risk factor occurr bovin mastiti southeastern par brazilian amazon survey dairi farmer identifi manag practic bovin breed characterist farm ml milk sampl collect microbiolog analysi somat cell count scc depend manag practic breed logit model use determin odd ratio subclin mastiti scm occurr irrig pastur scm associ risk factor occurr scm time higher non irrig pastur similar girolando breed herd occurr scm increas time compar crossbr herd moreov occurr mastiti time higher farm use common cloth dri teat farm use paper towel therefor adopt better manag practic lead scc reduct milk qualiti improv guarante contain scc within prescrib brazilian limit amazon region
|
D002418;D008414
|
T047
|
36,269,461
|
green synthesi character applic metal oxid nanoparticl mercuri remov aqueous solut work novel surfac modifi green base wheat straw support magnetit nanoparticl fe nps synthes via green synthesi method adsorpt mercuri hg ii ion aqueous solut method investig synthes wheat straw support magnetit fe wss nps character use x ray diffract xrd fourier transform infrar spectroscopi ft ir thermogravimetr analysi tga scan electron microscop sem method ft ir tga confirm surfac fe nps function well xrd analysi reveal exist magnetit synthes wheat straw support fe nps nm averag crystallin size sem analysi show fe nps almost spheric averag particl size nm adsorpt studi carri investig adsorpt hg ii ion onto fe wss nps effect various adsorpt paramet ph time adsorb dosag hg ii ion concentr optimum adsorpt condit obtain ph contact time min adsorb mgl adsorb g maximum hg ii ion remov effici obtain optimum condit ft ir analysi also indic surfac function group c c oh c c newli produc fe nps led effici remov hg ii aqueous solut synthes nano adsorb show excel adsorpt capabl mgg hg ii ion adsorpt onto fe wss nps fit well langmuir adsorpt isotherm model therefor reason find reveal fe wss nps effici promis adsorb hg ii remov aqueous water environ
|
D008628;D014874;D058185
|
T131;T196;T130
|
36,269,460
|
technolog use rumin graze manag integr review object studi identifi main technolog use manag rumin graze develop review protocol search term previous test base pvo strategi determin guid question popul p domest rumin variabl v interest graze manag technolog outcom intak perform product anim rais exclus pastur guid question follow technolog use graze manag domest rumin pastur databas use scopus elsevi scielo citat index scienc direct wiley onlin librari search carri octob search identifi research articl howev consid elig includ due methodolog robust data extract common use speci lolium multiflorum lolium perenn panicum maximum brachiaria brizantha wide use graze method continu graze intermitt graze among technolog wide adopt pastur height herbag allow frequent sampl method use ruler measur stick measur height clip frame measur herbag allow anim use includ studi cattl n sheep n goat n pastur height herbag allow wide use graze manag technolog data concentr main brazil studi continu graze cattl
|
D000821;D004032;D000822
|
T090;T168
|
36,269,455
|
impact subleth phenol freshwat fish labeo rohita biochem haematolog paramet phenol aromat chemic common found domest industri effluent upon introduct aquat ecosystem advers affect indigen biota invertebr vertebr increas demand agrochem larg amount phenol releas direct environ byproduct phenol deriv tend persist environ longer period turn pose threat human aquat ecosystem current studi respons labeo rohita subleth concentr phenol observ result show regular decreas biochem constitu target organ exposur labeo rohita subleth concentr phenol mgl epoch day show declin lipid protein carbohydr content phosphatas activ target organ gill muscl intestin liver kidney fish present studi also aim investig toxic effect phenol special refer haematolog paramet labeo rohita end exposur period blood fish collect cut caudal peduncl surgic scalpel observ red blood corpuscl count rbc white blood corpuscl wbc haemoglobin count hb pack cell volum pcv mean corpuscular volum mcv mean corpuscular haemoglobin mch mean corpuscular haemoglobin concentr mchc valu show declin exposur phenol day white blood corpuscl wbc show increas count day day haematolog paramet show signific decreas
|
D003530;D019800;D014873
|
T121;T109;T131;T013
|
36,269,452
|
combin salmonella phage st antibiot prevent salmonella typhimurium vitro novel phage st capabl infect foodborn pathogen salmonella typhimurium isol wastewat biolog charact genom inform st analyz vitro assay phage st moi effect inhibit growth salmonella typhimurium cgmcc h inhibitori effect combin phage st antibiot also studi remov rate plankton host expos st levofloxacin hydrochlorid time ciprofloxacin follow st higher expos antibiot dose group alon antibiot phage dose group phage st combin gml levofloxacin hydrochlorid result largest decreas biofilm biomass phage st could potenti agent control salmonella typhimurium growth provid instruct use antibiot togeth
|
D001435;D012483
|
T005
|
36,269,440
|
recent advanc semiconductor heterojunct z scheme photocatalyt hydrogen generat format semiconductor heterojunct z scheme still promin effici strategi materi chemist extend absorpt rang semiconductor combin moreov spatial separ photoexcit charg carrier therebi reduct recombin ultim lead increas photocatalyt activ present articl review recent trend semiconductor heterojunct z scheme focus hydrogen generat water split exhibit specif need charg carrier separ also includ recent materi trend ie dd combin direct z scheme mof cof combin upconvers materi
|
D012666;D014867
|
T121;T197;T073
|
36,269,439
|
environment surveil antimicrobi resist rapid develop catchment develop spread amr various sourc hospit pharmaceut industri anim farm human habit well understood conduct pilot studi assess preval amr take case rapid develop catchment western india select four sub catchmentsregion domin sourc antibiot viz area dens poultri farm farmskm b spars number poultri farm farmskm c agricultur field habit villag environment sampl soil litter water subject kirbi bauerantibiot disc suscept test assess resist pattern bacteri speci preliminari investig show presenc seven multidrug resist bacteri speci litter poultri farm five speci mar index greater evid amr observ vicin water soil poultri farm could attribut rigor disinfect protocol follow poultri farm prevent infect fresh batch chicken howev agricultur field litter use manur seven multipl drug resist two speci score mar index greater observ mar index less observ escherichia coli enterobact speci isol villag control site soil respect indic neglig contamin antibiot sub catchment studi provid approach investig effect multipl factor preval amr catchment scale
|
D000900;D024881
|
T121;T032;T195
|
36,269,438
|
compartment organ chip structur spatiotempor control oxygen microenviron hypoxia condit tissu oxygen level fall normal level local induc hypoxia due blood vessel blockag oxygen deliveri becom compromis site blood flow diminish form zero oxygen core differ oxygen zone form around core vari oxygen concentr natur differ oxygen microenviron drive cell respond accord oxygen status studi cellular process laboratori set cellular gas microenviron control rapid precis studi propos organ chip devic provid control oxygen environ three separ compart well possibl rapid chang correspond oxygen concentr propos devic includ microfluid channel structur three separ array narrow microchannel guid gas mixtur desir oxygen concentr diffus thin gas permeabl membran cell cultur area propos microfluid channel structur character use ratiometr oxygen imag system measur confirm oxygen concentr cell cultur surfac modul minut structur capabl creat hypox oxygen tension distinct oxygen environ generat simultan three compart combin microfluid channel structur open well cocultur devic multicellular cultur establish togeth compartment oxygen environ modul demonstr propos compartment organ chip structur suitabl cell cultur
|
D010100;D046210
|
T123;T196;T121;T059
|
36,269,437
|
variat multi time seri predict total hard groundwat guanzhong plain china use grey markov model total hard th import index repres water suitabl domest purpos th repres main ca mg essenti element human bone develop th valu groundwat major citi guanzhong plain vari signific studi carri investig th variat year examin effect grey markov model predict th concentr time seri dataset hydrochem paramet determin th concentr origin investig use statist analysi geochem model grey markov model effect short time seri predict use forecast multi time seri th find demonstr preval hco groundwat type combin calcit precipit gypsum dolomit dissolut increas concentr ca mg hco influenc th variat predict th valu eight monitor well year mgl respect dataset low th variat accur predict dataset high th variat especi observ sampl b th concentr mgl sudden drop mgl respect studi also show markov chain model optim gm model improv predict accuraci signific sampl weinan citi one sampl xian citi show signific decreas th concentr except one sampl xian citi th concentr tend rise citi baoji xianyang guanzhong plain studi verifi reliabl grey markov model term forecast time seri dataset high variabl result referenti similar studi world
|
D014874;D060587
|
T081;T131;T070;T082
|
36,269,436
|
water qualiti assess occurr seagrass associ pen shell pinna bicolor gmelin pinna deltod menk pudupattinam coastal area palk bay south east coast india pen shell speci pinna bicolor pinna deltod found muddi region associ intertid seagrass coastal area pudupattinam pen shell one sourc anim protein rich therebi encourag communiti pen shell studi worldwid water sampl collect year januari decemb analys salin ph ec valu mho turbid ntu tss valu mgl mll bod mgl chemic oxygen demand mgl chlorid mgl sulphat mgl ammonia ml inorgan phosphat ml maximum ml total nitrogen ml total phosphat ml silic ml minimum maximum water temperatur rang c record total pinna bicolor pinna deltod collect time consist male femal male femal respect improv paramet physico chemic statist analysi shown minor effect distribut two speci present research environment factor suffici influenc distribut
|
D060753;D061006
|
T033;T083
|
36,269,435
|
evalu climat socio econom influenc agricultur drought vulner jharkhand environment hazard like drought lead degrad food product advers impact agro economi studi investig contribut differ climat socio econom variabl agricultur drought jharkhand three primari criteria ie exposur e sensit adapt capac ac respons agricultur drought vulner examin identifi drought prone area long term grid climat dataset obtain terra climat global dataset modi veget index dataset modq year differ soil paramet obtain isric global soil databas state agricultur portal jharkhand differ socio econom dataset obtain census data provid govt india util studi analyt hierarchi process ahp use estim weight contribut indic variabl fall criterion e ac three criteria index map generat separ map integr generat final vulner index map final studi area categor differ zone base drought vulner index valu rang accord sever drought observ total geograph area high high moder vulner agricultur drought respect amongst three primari criteria exposur show signific posit correl r sensit show strong posit correl r vulner adapt capac negat correl r vulner howev put equal weight variabl calcul vulner exposur sensit indic show signific posit correl vulner r valu respect contrast adapt capac show negat correl vulner r
|
D055864;D004784
|
T070;T057
|
36,269,434
|
studi antimicrobi potenti actinomycet isol organ inorgan wast main object investig character collect actinomycet strain isol unexplor pollut ecosystem evalu antimicrobi potenti order discov interest bioactiv compound base morpholog cultur charact differ strain isol strain compost heap seven strain manur five strain wast water expect genus streptomyc preval follow genus micromonospora analysi antimicrobi activ isol strain show compost heap effici test microorgan candida albican methicillin resist staphylococcus aureus staphylococcus aureus acinetobact baumannii pseudomona aeruginosa escherichia coli sever bioactiv compound identifi liquid chromatographi lc combin mass spectrometri ms analyz medina databas contain common secondari metabolit dictionari natur product chapman hall mani interest well known unknown biomolecul identifi quinomycin daidzein fascin compound isol respect streptomyc sp ww streptomyc sp ww activ strain identifi base rdna sequenc seem new strain crude extract strain ch analyz uv absorpt spectra mass spectra ms main activ compound report interest compound possibl purpuromycin molecular formula cho
|
D039903;D055624;D004448;D013302;D000890;D001688
|
T123;T121;T007;T116;T195
|
36,269,432
|
hydrogeochem character groundwat lahor region use supervis machin learn techniqu cation anion composit groundwat better understood identifi type hydrogeochem process influenc groundwat chemistri research deal character groundwat sampl consid like role hydrogeochem process factor respons weather process studi appli statist method supervis machin learn algorithm ie logist regress model larg data set water sampl lahor district punjab pakistan water sampl collect local author deep unconfin aquif ft depth year character groundwat qualiti paramet includ ph total dissolv solid tds electr conduct ec total hard th calcium ca magnesium mg sodium na potassium k chlorid cl bicarbon hco nitrat sulfat result show sequenc major ion follow order na ca mg k hco cl ionic ratio gibb plot reveal promin hydrogeochem faci aquif water ca hco ca na hco mix ca mg cl type rock weather process especi carbon silic weather signific process control water chemistri statist evalu prepar regress model determin predict accuraci mean model high effici satisfi analysi outcom studi favor util method area larg data set
|
D014874;D060587
|
T081;T131;T070;T082
|
36,269,425
|
construct effici electrochemiluminesc reson energi transfer sensor base sno sns qds ru irmof composit sensit detect procalcitonin effici electrochemiluminesc reson energi transfer ecl ret method propos combin luminesc materi tris dicarboxylicacid bipyridyl ruthenium ii energi donor tin dioxid tin disulfid quantum dot sno sns qds energi acceptor isoreticular metal organ framework irmof materi form composit mode distanc energi donor acceptor great shorten reduc energi loss therebi effect improv ret effici signific improv ecl signal obtain composit sno sns qds ru irmof combin sandwich immunoreact construct ecl immunosensor sensit detect procalcitonin pct optim experiment condit work potenti v vs agagcl propos pct biosensor exhibit linear concentr rang ng ml detect limit pg ml sn biosensor use detect pct actual sampl biosensor broad applic prospect biolog analysi clinic diagnosi due high sensit good select good stabil
|
D015374;D000073396;D012428
|
T196;T059;T075;T109
|
36,269,423
|
paenibacillus hamazuiensi sp nov bacterium isol hamazui hot spring yunnan provinc south west china bacteri strain gram posit aerob rod shape motil design yim b isol hamazui hot spring tengchong yunnan provinc south west china strain grew well intern streptomyc project isp medium coloni creami yellow flat circular result rrna gene sequenc similar analysi show strain yim b close relat type strain paenibacillus filici main menaquinon strain yim b menaquinon mk major fatti acid anteiso c anteiso c c isol contain meso diaminopimel acid diagnost diamino acid major polar lipid diphosphatidylglycerol phosphatidylglycerol phosphatidylethanolamin phosphatidylmonomethylethanolamin four unidentifi glycolipid dna gc content strain yim b mol base physiolog phenotyp chemotaxonom data strain yim b belong novel speci genus paenibacillus name paenibacillus hamazuiensi sp nov propos type strain yim b cgmcc kctc
|
D045482;D056507
|
T070;T007
|
36,269,420
|
character microtubul associ protein tau isoform alzheim diseas like patholog normal sheep ovi ari relev potenti model alzheim diseas alzheim diseas chronic neurodegen diseas account dementia characteris deterior memori cognit function key neuropatholog featur accumul amyloid hyperphosphoryl tau plaqu tangl respect despit extens studi howev exact mechan under aggreg format alzheim diseas remain elus contribut aggreg diseas progress import recent evalu current alzheim diseas anim model suggest rodent model abl fulli recapitul patholog intricaci diseas occur human therefor increas attent paid speci might make good altern rodent studi molecular patholog alzheim diseas sheep ovi ari one speci although date molecular studi relat alzheim diseas sheep investig alzheim diseas relev histopatholog characterist sheep use anti amyloid abcam moc phosphoryl specif anti tau antibodi identifi numer intraneuron aggreg amyloid tau consist earli alzheim diseas like patholog confirm express two repeat nr nr two repeat nr nr tau isoform ovin brain result altern splice two tau exon final investig phosphoryl status serin residu sheep report phosphoryl residu begin sheep age young year togeth data show sheep exhibit natur occur amyloid tau patholog reflect occur earli stage alzheim diseas import step toward valid sheep feasibl larg anim speci model alzheim diseas
|
D000544;D019636;D016875
|
T123;T047;T116;T048
|
36,269,400
|
clonogen assay improv determin variant allel frequenc driver mutat myeloprolif neoplasm molecular diagnost move focus technolog advanc patient myeloprolif neoplasm mpn identif monitor driver mutat becom integr part diagnosi monitor diseas patient none known driver mutat jakvf calr mpl found term tripl negat tn also whole blood variant allel frequenc vaf driver mutat may adequ reflect vaf stem cell drive diseas reason coloni form unit cfu assay deriv clonogen cell may better suit next generat sequenc ngs whole blood detect driver mutat tn patient provid vaf diseas drive cell includ patient carri common driver mutat establish model interest clone effici correl whole blood vaf p suggest number diseas drive cell correl vaf furthermor clonogen vaf correl signific ngs vaf p correl lost patient ngs vaf analysi show patient vaf ngs clonogen vaf higher ngs vaf p suggest enrich low number diseas drive cell cfu assay howev approach enhanc identif driver mutat tn patient signific correl lactat dehydrogenas ldh serum level cfu ngs deriv vaf found result demonstr enrich clonogen cell improv detect mpn driver mutat patient low vaf ldh level correl vaf
|
D009369;D009196
|
T191
|
36,269,398
|
sex differ brain homotop co activ meta analyt studi element great interest function connect homotop connect hc name connect two mirror area two hemispher main mediat fiber corpus callosum despit long tradit studi sexual dimorph human brain knowledg one studi address influenc sex hcwe investig issu homotop co activ women men use coordin base meta analyt method data brainmap databas first unexpect observ databas affect sex bias women group investig less often men one often studi certain domain emot compar men less cognit implement seri sampl procedur equal size proport dataset result indic femal exhibit stronger interhemispher co activ male suggest femal brain less later integr male addit male appear show less intens extens co activ femal local differ also appear particular appear primari motor perceptu area co activ male contrast opposit trend rest brain argu multidimension view sex brain differ suggest issu approach complex model previous thought
|
D012727;D008279
|
T060;T032;T059;T170
|
36,269,387
|
acid center surfac crystallin sn iv phosphat character solid state h h p sn mas nmr techniqu layer crystallin phosphat sn hpo h prepar character present studi multinuclear solid state nuclear magnet reson nmr powder x ray diffract thermogravimetr analysi techniqu treat hod imit reaction condit water medium h solid echo magic angl spin nmr spectra product reveal surfac low mobil water molecul hydronium ion form structur close zundel cation od od deuteron hydronium ion tangl hydrogen bond water surfac phosphat group stabil ionic interact
|
D010710;D014867
|
T121;T197
|
36,269,359
|
associ symptom covid vaccin anti sar cov antibodi respons framingham heart studi cohort studi examin associ self report postvaccin symptom antisar cov antibodi respons among framingham heart studi particip contribut collabor cohort cohort covid research studi
|
D000086663;D000086382
|
T200;T047;T067
|
36,269,358
|
analysi us counti characterist clinician waiver prescrib buprenorphin chang feder educ requir cross section studi investig growth number clinician us obtain waiver prescrib buprenorphin elimin feder educ requir
|
D002047
|
T121;T109
|
36,269,357
|
variat human papillomavirus vaccin effect us age vaccin survey studi assess status time hpv vaccin self report femal particip nation health nutrit examin survey
|
D030361;D053918;D052685
|
T129;T121;T116;T005;T047
|
36,269,356
|
associ expir child tax credit advanc payment food insuffici us household advanc child tax credit ctc month payment administ million household children us juli decemb associ substanti decreas food insuffici month payment expir januari congress fail extend polici subsequ impact food insuffici current unknown
|
D005190;D013660
|
T099;T062;T079;T054;T081;T064
|
36,269,355
|
effect novel brief motiv intervent alcohol intox young adult emerg depart random clinic trial heavi drink among young adult major public health concern brief motiv intervent emerg depart shown promis inconsist result
|
D000435;D019973
|
T047;T048
|
36,269,354
|
priorit health care strategi reduc childhood mortal although child mortal trend decreas worldwid death among children younger year age remain high disproportion circumscrib sub saharan africa southern asia tailor innov approach need increas access coverag qualiti child health care servic reduc mortal understand health system defici may greatest impact mortal among children younger year lack
|
D046688;D066087
|
T081;T033
|
36,269,353
|
immedi postpartum long act revers contracept use follow state specif chang hospit medicaid reimburs facilit access full rang contracept option health polici goal howev inpati provis postpartum long act revers contracept larc method limit due lack hospit reimburs march januari medicaid program state began reimburs hospit immedi postpartum larc separ global matern payment
|
D008484;D000075523
|
T089;T064;T061
|
36,269,352
|
associ neonat pain relat stress parent interact intern behavior across year children born preterm intern anxieti andor depress behavior preval children born preterm week gestat procedur pain relat stress neonat intens care unit nicu associ long term intern problem popul howev whether posit parent toddlerhood attenu develop intern behavior across childhood unknown
|
D062071;D010290
|
T099;T100;T102
|
36,269,351
|
perspect histor black colleg univers advisor premed student covid pandem qualit studi black student remain underrepres medicin despit nation effort increas divers physician workforc histor black colleg univers hbcu student play vital role increas represent workforc current pauciti literatur understand impact covid premed student hbcus understand advers impact pandem hbcu student essenti inform strategi promot holist medic school admiss increas divers equiti inclus medic workforc
|
D013340;D000086382
|
T047;T067;T097
|
36,269,340
|
characterist termin medicar advantag contract cross section studi character medicar advantag contract termin identifi characterist enrolle may disproportion affect event
|
D020398
|
T033;T089
|
36,269,339
|
assess strategi use us hospit address social need covid pandem survey studi use american hospit associ data assess strategi us hospit serv vulner popul address social need covid pandem
|
D000086382
|
T047;T067
|
36,269,338
|
associ hospic payer concurr receipt hospic dialysi among us veteran end stage kidney diseas retrospect analysi nation cohort mani patient end stage kidney diseas eskd medicar hospic benefit preclud concurr receipt hospic dialysi servic forc patient choos continu dialysi enrol hospic whether liber hospic elig criteria veteran health administr va associ improv access concurr dialysi hospic care patient eskd known
|
D017051;D006738;D014728;D007676
|
T098;T073;T093;T058;T047
|
36,269,326
|
chopstick like structur free transfer microdroplet robot chemistri laboratori know chopstick hold food use method carri newtonian fluid droplet paper studi process transfer use method realiz manipul open microfluid robot realiz transfer oper first analyz forc droplet chopstick like structur found bidirect movement droplet structur achiev chang structur paramet afterward whole process transfer droplet use chopstick like structur analyz paramet requir realiz transfer determin research paper provid theoret basi control manipul droplet wide use unman laboratori
|
D012371
|
T090
|
36,269,324
|
self power respiratori monitor strategi base adapt dual network thermogalvan hydrogel low grade sustain heat sourc breath wast heat exhal human bodi alway ignor although produc greater temperatur ambient convert heat electr energi use power sourc detect signal extrem import cut edg wearabl medicin heat electr convers possibl thermogalvan hydrogel howev challeng remain antifreez antidri properti signific restrict durabl thermogalvan gel practic applic herein dual network poli vinyl alcohol gelatin pvagel gel thermogalvan devic fe cn redox pair develop outstand low temperatur durabl antidri capac featur result use binari h ogl glycerin solvent limit hydrogen bond water molecul prepar thermogalvan gel patch capabl easili convert physiolog data understand electr impuls use temperatur differ ambient environ heat produc human breath realiz simpl self power respiratori monitor strategi first time even zero temperatur gel patch base mask oper normal impli fit low temperatur environ studi shed fresh light develop activ wearabl medic electron power demic low level heat
|
D020100;D011142
|
T121;T122;T109
|
36,269,321
|
generat rat monoclon antibodi mous nucleolin immun ferroptosi induc hepa cell nucleolin multifunct phosphoprotein ubiquit distribut nucleus nucleoplasm cytoplasm cell membran princip function nucleolin involv dna rna metabol gene transcript translat ribosom biogenesi mrna stabil ferroptosi type regul cell death character iron depend accumul lipid peroxid product previous studi produc monoclon antibodi mab lysat prepar ferroptosi induc hepa cell studi describ one rat mab b generat mous nucleolin mab use immunofluoresc stain immunoblot immunoprecipit experi confirm recogn endogen nucleolin mous cell line tissu anticip mab b use function analys nucleolin
|
D000911;D000079403
|
T129;T116;T043
|
36,269,318
|
new insight deposit zearalenon minipig suitabl bioindic intern exposur detriment footprint mycotoxin agricultur anim product wide recogn especi swine despit increas number research evalu toxicokinet mycotoxin anim organ absorpt distribut metabol excret adm pattern zearalenon zen need understand furthermor vivo bioindic zen exposur individu pig yet character studi explor adm zen bama aroma pig chines miniatur pig breed use herein swine model find reveal zen main metabol zearalenol zol zen zol most found conjug form plasma urin bile concentr composit pattern zen metabolit tissu specif impli small intestin liver kidney lung play differ role zen metabol plasma concentr zen zol high correl r zen dietari exposur may util bioindic investig anim exposur mitig efficaci mycotoxin detoxifi research would provid fundament inform use anim model zen toxic detoxif studi
|
D015025;D009183
|
T131;T109
|
36,269,312
|
investig unexpect photocycloaddit synthesi scabrolid quantum mechan calcul util ab initio quantum mechan calcul evalu rang plausibl mechanist pathway unexpect format ring system enon olefin photocycloaddit synthesi scabrolid previous report group present mechanist analysi consist current experiment observ includ photoexcit c c bond format associ chemo diastereoselect
|
D011789
|
T170
|
36,269,304
|
graphen oxid acceler diabet wound repair inhibit apoptosi ad mscs via lincmir stk pathway mani studi shown graphen oxid go promot prolifer differenti varieti stem cell howev effect adipos deriv mesenchym stem cell ad mscs apoptosi still unclear apoptosi signific factor affect stem cell base treatment diabet wound therefor explor effect go ad msc apoptosi diabet wound heal studi qrt pcr use detect ad msc express lncrnas mirna mrnas high glucos environ rna immunoprecipit rip rna pull luciferas assay use detect interact specif lncrnas mirna mrnas effect go ad msc apoptosi explor flow cytometri tunel assay western blot diabet wound model use explor function linc ad msc repar properti vivo result go inhibit high glucos induc apoptosi ad mscs linc contribut anti apoptot effect go rip rna pull confirm linc direct interact mir function mirna spong regul express mir target gene stk mst downstream signal pathway addit go reduc apoptosi ad mscs wound promot wound heal taken togeth find suggest go may superior auxiliari materi ad mscs facilit diabet wound heal via lincmir stk pathway
|
D003920;D059630;D035683;D062085;D014945;D006108
|
T123;T025;T109;T196;T040;T114;T047
|
36,269,301
|
antimicrobi resist pattern virul determin molecular analysi carbapenem resist klebsiella pneumonia isol clinic sampl iran carbapenem resist klebsiella pneumonia crkp emerg import global threat recent year object present studi character molecular characterist antibiot resist pattern distribut virul factor crkp isol differ clinic specimen total clinic crkp isol collect clinic sampl base clinic laboratori standard institut guidelin antimicrobi suscept test assess disk diffus method carbapenem aminoglycosid resist determin addit virul gene inspect pcr molecular characterist crkp isol analyz random amplifi polymorph dna rapd pcr enterobacteri repetit intergen consensus eric pcr isol resist imipenem meropenem cefoxitin levofloxacin cefotaxim ceftazidim ciprofloxacin resist tetracyclin gentamicin kanamycin detect isol respect common carbapenem resist gene oxa ndm common aminoglycosid resist gene aacib aac iva preval virul gene mrkd entb ybts eric rapd analys reveal differ pattern crkp isol respect conclud crkp infect associ differ genotyp carbapenemas type oxa ame gene aac ib wide distribut crkp isol hospit continu complianc exist phenotyp genotyp strict enforc infect control guidelin recommend approach prevent dissemin strain
|
D007711;D007710
|
T047;T007
|
36,269,299
|
primari tumor deriv system nangptl inhibit metastasi primari tumor distant site metastas form bidirect communic system yet molecular mechan crosstalk poor understood identifi proteolyt cleav fragment angiopoietin like angptl contextu activ protumorigen antitumorigen contributor communic ecosystem preclin studi multipl tumor model reveal c termin fragment cangptl promot tumor growth metastasi contrast n termin fragment angptl nangptl inhibit metastasi enhanc overal surviv postsurg metastasi model inhibit wnt signal reduc vascular metastat site trace angptl fragment tumor patient detect full length angptl primarili tumor tissu wherea nangptl predomin system circul correl invers diseas progress studi highlight spatial context proteolyt cleavag depend pro antitumorigen function angptl identifi valid nangptl novel biomark tumor progress antimetastat therapeut agent
|
D000075803;D009369
|
T123;T191;T116
|
36,269,293
|
univers newborn eye screen systemat review literatur review intern guidelin systemat review assess effect univers screen newborn eye abnorm compar screen improv infant vision health outcom
|
D002386
|
T033;T047;T190
|
36,269,291
|
effect biofeedback music train programm reduc stress thai patient live cancer receiv palliat care stress physic effect patient cancer undergo palliat care target prevent
|
D009146;D009369
|
T170;T191
|
36,269,290
|
experi emerg depart nurs use palliat care resourc associ tool provis qualiti care die patient access qualiti palliat end life care emerg depart vital import care stage life studi aim investig nurs percept use suit dedic resourc support provis care patient die emerg environ studi follow qualit descript design semi structur interview conduct analys use themat code five theme develop facilit care deliveri comfort environment adjust visual symbol develop knowledg overcom fear percept famili experi increas need access palliat care emerg depart use suit resourc play import role provis qualiti care die
|
D013727;D064946
|
T058;T091
|
36,269,289
|
nurs knowledg palliat care servic north lebanon surg number peopl need palliat care servic along deficit nurs knowledg field challeng address order ensur higher qualiti end life life care
|
D010166;D009726
|
T061;T097
|
36,269,287
|
reflect palliat care children young peopl famili revis model uniqu need children requir palliat care famili increas recognis global scale complex care unpredict ill trajectori increas choic term care provid led challeng nursespractition strive provid optim care famili work partnership children famili reflect practic key issu provid care support reflect model frequent use tool two reason first reflect practic aim qualiti improv second help practition explor difficult challeng aspect care negoti famili author report specialis model develop updat use within children palliat care reason confidenti fictiti case studi use illustr model could implement debrief session follow death child research need initi trial model author suggest use specialis reflect model framework help facilit discuss children palliat care
|
D010166;D064946
|
T061;T058;T091
|
36,269,286
|
qualiti death relat factor termin ill patient perceiv nurs littl known qualiti death termin ill patient hospit thailand
|
D064946;D009726
|
T058;T091;T097
|
36,269,282
|
benchmark taxonom classifi illumina nanopor sequenc data clinic metagenom diagnost applic cultur independ metagenom detect microbi speci potenti provid rapid precis real time diagnost result howev potenti limit sequenc taxonom classif error use simul real world data benchmark rate speci misclassif use refer genom ten common bloodstream pathogen six frequent blood cultur contamin n genom avail micrococcus luteus simul without sequenc error illumina oxford nanopor platform evalu common use classif tool includ kraken bracken centrifug util mini gb standard gb databas bracken standard databas perform best median percentag read across sequenc platform identifi correct speci level iqr rang kraken mini databas common use combin median speci level identif iqr rang classif perform vari speci escherichia coli challeng classifi correct probabl read assign correct speci vari tool use human read misclassif neglig filter shorter nanopor read found perform similar superior illumina sequenc despit higher sequenc error rate misclassif common misclassifi speci higher averag nucleotid ident true speci find highlight taxonom misclassif sequenc data occur vari sequenc analysi workflow account bioinformat contamin present contamin catalogu use metagenom pipelin ensur accur result support clinic decis make
|
D058608
|
T082
|
36,269,280
|
endotheli cypj overexpress restor brb via mettl mediat anxa upregul blood retin barrier brb breakdown respons multipl ocular diseas diabet retinopathi age relat macular degener retin vascular occlus diseas increas vascular permeabl contribut vasogen edema tissu damag consequ advers effect vision herein found endotheli cypj overexpress maintain brb integr ischemia reperfus injuri consequ protect retin ganglion cell loss oxid stress repress endotheli anxa express vivo vitro cypj upregul methyltransferas like mettl express henc promot anxa translat via anxa modif endothelium oxid stress cypj maintain distribut endotheli tight junction adheren junction anxa depend manner endotheli anxa play indispens role vascular homeostasi stabil develop endotheli anxa delet disrupt retin vascular perfus well brb integr cypj metabolit restor brb integr presenc anxa find identifi cypj mettl anxa pathway potenti therapeut target reliev brb impair
|
D001813;D000090762;D012164
|
T047;T126;T116;T042
|
36,269,278
|
new dual p glycoprotein p gp human carbon anhydras xii hca xii inhibitor multidrug resist mdr revers cancer cell continu search dual p gp hca xii inhibitor synthes studi new n n bis alkanol amin aryl diester deriv character presenc coumarin group hybrid contain p gp hca xii bind group synergist overcom p gp mediat multidrug resist mdr cancer cell express p gp hca xii inde hca xii modul efflux activ p gp inhibit hca xii reduc intracellular ph therebi decreas atpas activ p gp compound show inhibitori activ p gp hca xii protein taken individu mani display synergist effect htdox adox cell overexpress p gp hca xii potent kdox cell overexpress p gp compound identifi promis chemosensit agent select inhibit mdr cancer cell overexpress p gp hca xii
|
D002256;D009369
|
T191;T126;T116
|
36,269,266
|
greyhound race ban georgina mill report chang tack welfar chariti want greyhound race ban good
|
D002608
|
T095
|
36,269,262
|
necessari support survey found one women left work symptom caus menopaus world menopaus awar month continu laura black vet say crucial introduc support avoid lose expertis workforc clair read report
|
D008593;D018634
|
T039;T097
|
36,269,260
|
good natur whole host evid show time natur improv physic mental wellb catriona mellor child adolesc psychiatrist tell clair read
|
D014730
|
T091
|
36,269,257
|
introduc apprenticeship rout veterinari medicin matt ashford argu address continu shortag vet perhap profess look preced set medic profess consid apprenticeship rout vet train
|
D018634;D014730
|
T091;T097
|
36,269,233
|
heal potenti propoli extract passiflora eduli seed oil emulgel excision wound biochem histopatholog cytokin level evid propoli rich natur bioactiv compound consid import mani skin therapi emulgel prepar studi examin propoli extract pe passiflora eduli seed ps oil emulgel affect rat deep skin wound heal base preset criteria maximum drug content optimum drug permeat stratum corneum along drug retent skin layer optim emulgel formula base box behnken factori design prepar use subsequ vitro vivo evalu vivo wound heal activ emulgel control treatment investig rat model optim emulgel formula exhibit superior heal activ compar plain pe suspens treat rat day wound histopatholog investig hematoxylin eosin masson trichrom stain skin section support effect emulgel promot cutan wound heal varieti mechan includ anti inflammatori modul cytokin tumor necrosi factor interleukin il il product promot collagen fiber format contribut tissu remodel furthermor compar propoli suspens emulgel show signific antioxid anti inflammatori effect emulgel signific increas skin hydroxyprolin level antioxid potenti wound contract increas penetr local propoli deposit across skin incorpor ps oil emulgel acceler tissu regener process find suggest propoli emulgel could use altern treat wound
|
D029598;D011429;D014945
|
T121;T123;T109;T168;T040;T002
|
36,269,231
|
comput design phosphatidylinositol kinas inhibitor one sought therapeut target treat human cancer phosphoinositid kinas pik integr part pikprotein kinas b signal arcad pathway frequent activ malign drug resist dose limit advers effect current associ challeng exist anticanc chemotherapi therefor research seri pyrimidin deriv design evalu human pik use molecular dock analysi dock result verifi molecular dynam simul analyz strength macromolecular complex respect time compound iv xiv found potent inhibitor human pik receptor high degre stabil within activ site target receptor timefram ns thus compound could import drug candid develop pik inhibitor prospect anticanc agent
|
D000970;D015195;D000081082
|
T090;T121;T109
|
36,269,226
|
vinculin recruit catenin halt differenti matur enterocyt progenitor maintain homeostasi drosophila intestin mechan communic chang tissu stiff size particular relev intestin subject constant mechan stress caus peristalsi variabl content use drosophila intestin epithelium investig role vinculin one best characteris mechanoeffector function cadherin integrin adhes complex discov vinculin regul cell fate decis prevent precoci activ differenti intestin progenitor absorpt cell achiev concert catenin site cadherin adhes rather part integrin function follow asymmetr divis stem cell stem cell enteroblast eb two cell initi remain connect adheren junction vinculin requir eb side maintain eb quiescent state inhibit divis stem cell manipul cell tension show vinculin recruit adheren junction regul eb activ number consequ remov vinculin result enlarg gut improv resist starvat thus mechan regul contact stem cell progeni use control tissu cell number
|
D004330;D020895
|
T025;T204
|
36,269,223
|
carbon nanodot base near infrar photosensit protein ruthenium shell low power photodynam applic near infrar nir light activ photosensit repres encourag therapeut method photodynam therapi especi deep tissu penetr context two photon activ ie util photon relat low energi high photon flux popul virtual intermedi state lead excit state attract concept would high advantag photodynam therapi due minim side effect herein propos combin plasma protein serum albumin hsa contain sever ru complex nir two photon excit carbon nanodot cdot term hsa ru cdot provid sever attract featur enhanc singlet oxygen format within mitochondria cancer cell stimul two photon excit nir region hsa ru cdot featur biocompat water solubl photost well uptak cancer cell endosom releas essenti featur subcellular target mitochondria nir two photon excit induc visibl emiss cdot allow fluoresc reson energi transfer fret excit metal ligand charg transfer ru moieti fluoresc lifetim imag microscopi flim appli demonstr fret within cell nir two photon excit indirect transfer ru complex lead product singlet oxygen within mitochondria cancer cell consequ observ destruct filament mitochondri structur spheroid aggreg within various cancer cell line cell death induc long wavelength nir light irradi nm low power densiti mwcm could attract phototherapi applic deeper tissu penetr crucial
|
D012428;D010778
|
T061;T196
|
36,269,221
|
bimetal metal organ coordin polym facilit select c f cleavag polyfluoroaren select c f bond cleavag polyfluoroaren attract tremend interest due promis applic introduc fluorin build block organ molecul howev remain challeng achiev high site select c f bond cleavag intrins inert c f bond difficulti distinguish specif c f bond aromat ring herein report effici nucleophil aromat substitut n ar reaction polyfluoroaren grignard reagent employ mnfe base bimetal metal organ coordin polym mocp recycl reusabl heterogen catalyst signific reaction prepar mocp mn fe catalyst exhibit excel activ select c f bond cleavag afford seri function polyfluoroaren moder excel yield work highlight potenti mocp catalyst serv tunabl platform lewi acid catalysi
|
D011108;D008670
|
T104;T122;T197
|
36,269,216
|
high respons rate low cost wechat base data collect infant young child feed data rural qinghai provinc china measur infant young child feed iycf indic key effect track progress child health program make evid base decis wechat popular mobil social media platform china becom promis tool collect health data studi aim explor respons rate cost wechat base questionnair iycf inform rural china
|
D012424;D005247
|
T055;T040;T098;T102
|
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