PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,257,739 | endoplasm reticulum target fluoresc probe visual viscos fluctuat ferroptosi live cell ferroptosi uniqu iron depend cell death form current shown close relat er reveal viscos fluctuat er ferroptosi great signific monitor occurr develop iron poison also deepli understand biolog effect er ferroptosi herein present er target fluoresc probe pv detect viscos chang er ferroptosi pv util rotat c c bond connect two rigid system respond viscos regul coplanar two plane pv display desir sensit select viscos biolog imag result suggest pv main distribut er live cell viscos er exhibit evid increas process erastin induc ferroptosi simultan incub cell erastin fer viscos er show mark chang suggest erastin induc ferroptosi could inhibit fer expect develop probe could provid feasibl rapid method depth studi ferroptosi base diseas treatment drug design | D000079403 | T043 |
36,257,738 | stabl sensit sensor alkalin phosphatas base target trigger wavelength tune fluoresc copper nanoclust general volatil vulner intens signal larg reduc reproduc stabil fluoresc nanosensor herein propos novel stabl fluoresc sensor employ wavelength shift copper nanoclust cunc signal readout thymin templat cunc prepar facil rapid one pot reduct method interest import found fluoresc wavelength cunc could precis tune manganes ion mn systemat investig prove wavelength readout cunc signific stabl intens readout sinc alkalin phosphatas alp catalyz hydrolysi phosphoryl ascorb acid ascorb acid aa trigger decomposit mno nanosheet ns mn stabl sensor sensit alp detect construct base precis wavelength tune fluoresc cunc sensor exhibit good linear respons alp rang ul detect limit ul addit sensor also extend assay two typic alp inhibitor na vo edta reason result last least confirm detect result alp real serum sampl sensor high consist data clinic test main attribut improv stabil practic wavelength readout base sensor | D003300;D053768 | T123;T196;T121;T073 |
36,257,737 | supercrit fluid analysi cannabinoid various cannabi product develop fast select sensit method determin various neutral acid phytocannabinoid emphasi separ structur relat compound optim ultra high perform supercrit fluid chromatographi uhpsfc allow separ group structur isom includ isom mz cannabidiol tetrahydrocannabinol acid isom mz cannabichromen tetrahydrocannabinol tetrahydrocannabinol cannabicyclol cannabidiol mere min follow min equlibr ethylpyridin function stationari phase gradient elut use mobil phase compris carbon dioxid methanol acetonitril water mixtur select optim tandem mass spectrometri msms electrospray ionize posit negat mode methanol water make solvent provid adequ select sensit need analysi phytocannabinoid complex matric limit quantif rang ngml monitor cannabinoid optim uhpsfc msms method use determin cannabinoid various product dietari supplement nutraceut cosmet solvent extract method optim cosmet nutraceut product accuraci rang precis extract cannabinoid herbal infus matrix supercrit fluid extract sfe pressur liquid extract ple method develop use environment friend solvent water ethanol carbon dioxid detail optim extract solvent composit temperatur pressur carri emphasi avoid thermal degrad cannabinoid optim sfe ple method compar appli differ herbal infus confirm declar cannabinoid content | D002188;D002185;D002186;D025924 | T121;T167;T109;T059;T002 |
36,257,736 | ratiometr fluoresc detect mirna via ph regul adsorpt dna polym dot exonucleas iii assist amplif work propos simpl sensit method ratiometr fluoresc detect nucleic acid via ph depend adsorpt dye label dna polym dot polym dot pdot could conveni prepar nanoprecipit water mixtur dye label dna pdot neutral ph show fluoresc pdot adsorpt dye label dna pdot acid ph led fluoresc reson energi transfer pdot dye thus fluoresc dye result signal switch could design detect nucleic acid complementari dna combin exonucleas iii assist digest dna use mirna target model cy label dna probe hybrid dna mirna provid activ site exo iii releas hybrid mirna cyclic digest dna thus decreas adsorpt cy label dna pdot fluoresc cy ratio fluoresc intens pdot cy show linear increas upon increas mirna concentr rang nm limit detect pm excel perform good extend propos strategi demonstr promis applic bioanalysi | D015374;D035683 | T123;T059;T075;T114 |
36,257,735 | novel fluoresc biosensor base doubl strand dna branch migrat induc hcr dnazym feedback circuit sensit detect pseudomona aeruginosa clean version pseudomona aeruginosa p aeruginosa one common bacteria nosocomi infect novel fluoresc biosensor base doubl strand dna branch migrat induc hybrid chain reaction hcr dnazym feedback circuit construct sensit detect p aeruginosa bind p aeruginosa aptam dna three way junction structur initi doubl strand dna branch migrat form two dna junction structur one dna junction structur open fluoresc label dna hairpin trigger hcr dna junction structur form doubl strand dnazym cleav specif ribonucleotid site produc new trigger probe start next cycl doubl strand dna branch migrat ultim larg number dna junction structur produc great promot signal amplif optim condit propos biosensor detect wide linear rang cfu ml limit detect cfu ml sn recoveri test result indic biosensor promis clinic applic potenti simultan initi hcr dnazym feedback circuit doubl strand dna branch migrat construct biosensor provid ideal platform pathogen bacteria detect without protein enzym complex signal amplif procedur | D021881;D015374 | T116;T075;T059;T126;T114 |
36,257,734 | machin learn base multimod electrochem analyt devic base emo x lig multiplex detect tyrosin uric acid sweat saliva multiplex detect biomolecul great valu various field diseas diagnosi food safeti environment monitor howev accur multiplex analyt detect challeng achiev mixtur use singl devicemateri paper demonstr machin learn ml power multimod analyt devic base singl sens materi made electrodeposit molybdenum polysulfid emo x laser induc graphen lig multiplex detect tyrosin tyr uric acid ua sweat saliva electrodeposit mos x show increas electrochem activ surfac area ecsa heterogen electron transfer rate constant k featur extract electrochem data order train ml model predict analyt concentr sampl singl spike mix sampl differ ml architectur explor optim sens perform optim ml base multimod analyt system offer limit detect lod two order magnitud better convent approach reli singl peak analysi flexibl wearabl sensor patch also fabric valid bodi achiev detect ua tyr sweat wide concentr rang perform develop approach demonstr detect tyr ua use emo x lig sensor general analyt methodolog extend varieti electrochem sensor enabl accur reliabl multiplex sens | D006108;D000080745;D015374 | T073;T075;T109;T196;T059 |
36,257,733 | novel approach base gqd phb anchor platform develop sar cov electrochem immunosensor present work report innov approach immunosensor construct experiment strategi base anchor biolog materi screen print carbon electrod spe modifi electrodeposit graphen quantum dot gqd polyhydroxybutyr acid phb use function substract basi recognit site receptor bind domain rbd coronavirus spike protein sar cov detect anti antibodi ab sem imag ed spectra suggest interact protein gqd phb site electrod surfac differenti puls voltametr dpv measur perform incub presenc target shown decreas voltametr signal electrochem probe fe cn use optim experiment condit analyt curv perform pbs human serum spike ab show slight matrix effect relationship voltametr signal ab concentr rang ng ml g ml select propos sensor test yellow fever antibodi yf select layer electrod surfac interact unspecif antibodi eight sampl blood serum analyz total investig provid adequ result addit present approach show better result tradit edcnh reaction enhanc time possibl develop immunosensor singl drop sinc protein anchor prior electrod modif step | D006108;D045663;D015374;D000086382 | T073;T075;T109;T067;T196;T059;T047 |
36,257,732 | cascad primer exchang reaction base amplif strategi sensit portabl detect amyloid oligom use person glucos meter amyloid oligom ao import biomark almerzheim diseas ad earli diagnosi present studi cascad primer exchang reaction per base amplif strategi propos sensit portabl detect ao use person glucos meter pgm two per process employ primari per hairpin templat ht design primer bind domain primer extend domain block extend domain primer design modifi magbead surfac initi primer bind domain ht lock ao aptam target ao present aptam bound ao dissoci ht initi primari per product act primer secondari per hybrid anoth hairpin templat ht initi secondari per produc numer ssdna repeat dna invertas bind site bind dna invertas obtain conjug magnet separ catalyz convers sucros glucos detect pgm strategi achiev limit detect pm linear rang pm pm satisfactori reproduc result obtain actual sampl strategi provid superior tool sensit conveni detect ao show great potenti earli diagnosi ad | D005947;D015374 | T123;T121;T075;T109;T059 |
36,257,731 | develop zno nanoflow assist dnazym base electrochem platform invertas glucos oxidas domin biosens investig invertas inv glucos oxidas gox domin biolog process offer new opportun develop clinic diagnosi prognost treatment herein zno nanoflow znonf assist dnazym base electrochem platform inv gox domin biosens propos chang ph microenviron strategi inv usual catalyz dissolut sucros generat glucos glucos consum gox produc h glucon acid znonf effect etch free zn ion subsequ releas zn ion shear action zn specif dnazym thus trigger hybrid chain reaction along imbed methylen blue excel electrochem signal illustr method employ well test sucros inv gox low detect limit muml muml respect final seri basic advanc logic gate yes inhibit inhibit biolog process construct differ logic input provid valuabl platform establish advanc molecular devic bioanalysi clinic diagnost | D021881;D015034;D015374 | T121;T116;T075;T197;T059;T126;T114 |
36,257,730 | target initi dna releas direct catalyt hairpin assembl base ultrasensit cyclic amplif sensor detect serum mirna microrna mirna import biomark varieti diseas develop enzym assist cyclic amplif strategi electrochem method base high sensit target specif catalyt hairpin assembl cha reaction trace mirna detect serum mirna period trigger hairpin probe h h form three way structur dna cha reaction accompani releas singl strand dna ssdna mirna ssdna bind methylen blue mb label signal probe h mb immobil electrod cleav explicit action enzym ntbbvci result part mb contain fragment leav electrod surfac time ssdna rereleas reus initi new round enzym assist cleavag integr multipl signal amplif electr signal quench effect enabl strategi low limit detect lod fm also use mirna detect serum sampl furthermor strategi potenti use clinic analysi mirna | D035683;D015374;D021881 | T123;T116;T075;T059;T126;T114 |
36,257,729 | function graphen quantum dot obtain graphen foam use high select detect hg real sampl report use graphen quantum dot gqds obtain graphen foam function hydroxyquinolin hq sensit select detect hg via front face fluoresc great surfac area activ group within gqds permit function hq increas select toward analyt interest fluoresc probe follow stern volmer model yield direct relationship degre quench concentr analyt divers paramet includ ph use mask agent optim order improv select toward hg limit detect nmol l herebi demonstr function gqds work perfect fine advers condit acid ph presenc larg number cation anion interfer detect hg real sampl parallel measur use cold vapor atom fluoresc spectrometri also demonstr excel correl front face fluoresc method appli real sampl includ tap river underground dam water | D045663;D006108;D008628 | T131;T196;T073;T109 |
36,257,728 | develop comprehens two dimension liquid chromatograph mass spectrometr method non target identif poli perfluoroalkyl substanc aqueous film form foam research develop onlin comprehens two dimension liquid chromatograph lc lc method hyphen high resolut mass spectrometri hrms non target identif poli perfluorin compound pfass fire fight aqueous film form foam afff method exploit combin mix mode weak anion exchang revers phase octadecyl stationari phase separ pfass accord ionic class chain length develop optim lc lc method use refer train set twenti four anion pfass repres main class compound occur afff cover wide rang physicochem properti particular investig differ modul approach reduc inject band broaden breakthrough second dimens separ activ solvent stationari phase assist modul compar best result obtain last approach optim condit predict peak capac correct undersampl higher three hundr separ space min subsequ develop method appli non target analysi two afff sampl identif homolog seri pfass possibl identifi thirti nine potenti compound interest util kendrick mass defect analysi even within sampl featur consid potenti pfas mass defect analysi elut chromatograph region discrimin ionic group andor chain length thus confirm applic method present analysi afff mixtur extent environment matric affect afff | D005466;D014874 | T131;T109 |
36,257,727 | fluoresc colorimetr sensor base ionic liquid site monitor trace gaseous could caus sever environment pollut health threat real time site monitor attract consider attent work propos novel ionic liquid base sensor call trihexyl tetradecyl phosphonium fluorescein ionic liquid accur detect fluoresc colorimetr dual readout assay without seventeen gase interfer eg n co cos hcl chcl gc ms also use verifi valid detect method first fluorescein base il sensor exhibit fluoresc green colorimetr yellow signal sensor expos gaseous green fluoresc quench colorimetr yellow color fade due chemic bond interact also propos il sensor exhibit good linear concentr rang ppm detect limit ppm fluoresc ppm colorimetri recoveri rsd less besid il sensor could easili assembl paper devic simpl immers paper strip exploit realiz semiquantit visual detect result indic propos fluoresc colorimetr dual signal chemosensor could use intellig paper label real time site monitor ambient air | D003124;D052578 | T120;T059;T103 |
36,257,701 | primari care evalu hepat c virus hcv screen educ intervent increas screen effort develop effect antivir treatment led mark improv hepat c hcv patient outcom howev mani peopl us believ undiagnos hcv success screen strategi access coordin system care critic hcv affect adult object studi evalu primari care hcv screen educ intervent took place improv primari care train manag patient implement electron medic record emr screen alert | D016174;D006526 | T005;T047 |
36,257,700 | primari care critic stopgap mental health servic covid pandem covid pandem result worsen mental health crisi also dramat reduc access person primari care servic primari care essenti provid mental health servic rapid adopt telemedicin address behavior health need examin provis mental health servic primari care pandem includ essenti use telemedicin method data collect via seri nation cross section survey primari care clinician novemb larri green center survey distribut network partner organ subscrib descript chi squar analysi util result among respond report increas mental health need report higher rate substanc use among patient clinician becam involv provid mental health support report use telemedicin provid behavior health servic phone base care common care deliveri among patient uninsur vs p medicar beneficiari vs p non english speak vs p racial ethnic minor vs p conclus primari care lead provid mental health servic play critic role pandem primari care clinician strong relationship patient well outreach within communiti may otherwis struggl access mental health servic use telemedicin primari care specif phone base servic essenti tool provid equit access mental health servic | D000086382;D017216;D008605 | T047;T058;T067 |
36,257,698 | self perceiv mental health perceiv discrimin famili physician resid compar studi men women present studi aim examin sex differ demograph variabl profession activ advers self report mental health problem perceiv discrimin sampl famili doctor famili medicin resid mexico method larger sampl medic specialist analyt cross section studi conduct particip includ famili medicin resid famili doctor mexico onlin survey demograph featur profession activ advers mental health perceiv discrimin examin descript compar analys perform cramer v chi squar test hedg g test conduct determin effect size result sex display similar percentag profession advers attend patient suicid behavior die suicid care higher number women report seek special support cope death fisher men perceiv greater discrimin p work hour per day p verbal assault p wherea women report mental health problem frequent p particular depress anxieti burnout sleep problem women also report wors health status p compar men conclus famili medicin specialist constitut vulner group mental health problem perceiv discrimin particular attent paid men women cope profession advers determin whether addit support requir intervent encourag self care promot well health personnel | D008603;D002055 | T041;T048 |
36,257,697 | famili physician racial ident analysi race select implic futur data collect famili physician report race singl best option question find exist categori forc choic one categori problemat analysi open text respons race categori support modif way data collect provid accur meaning way understand workforc move toward divers equit inclus polici famili medicin | D010821;D018864 | T078;T077;T097 |
36,257,696 | mental health patient clinician covid pandem mental health patient clinician pandem investig report multipl investig improv health practic chang challeng possibl telehealth increas dramat sinc begin pandem futur | D000086382;D017216 | T047;T058;T067 |
36,257,695 | evidencenow practic support initi heart virginia healthcar hhs million heart campaign focus deliveri system abc clinic qualiti measur appropri aspirin use blood pressur control cholesterol control smoke cessat counsel ahrq evid project fund collabor test differ way improv perform outcom abc within small primari care practic heart virginia health care hvh collabor design approach evid | D011320;D002318 | T058;T047 |
36,257,694 | pain manag west virginia opioid crisi opioid use disord caus signific morbid mortal result opioid prescrib limit law state bill west virginia purpos studi explor impact restrict opioid prescript law physician medic practic west virginia | D000080052;D059350 | T068;T047;T184 |
36,257,692 | transcript profil develop subthalam nucleus subthalam nucleus stn small excitatori nucleus regul output basal ganglia motor circuit function stn role pathophysiolog parkinson diseas well establish howev basic characterist like development origin molecular phenotyp neuron subpopul still debat classic model forebrain develop attribut origin stn within diencephalon recent studi gene express pattern expos shortcom classic model accommod find prosomer model develop concept stn develop within hypothalam primordium longer part diencephal primordium concept support express pattern mani transcript factor interest note mani transcript factor involv develop stn also involv pathogenesi neurodevelopment disord thus studi neurodevelopment disord could provid us valuabl inform role transcript factor develop mainten stn phenotyp review summar histor theori development origin stn interpret gene express data within prosomer conceptu framework final discuss import neurodevelopment disord develop stn potenti role pathophysiolog neurodevelopment disord | D020531;D010300 | T023;T047 |
36,257,685 | infecti diseas control achiev without antibiot exploit mechan diseas toler antimicrobi use anim agricultur may contribut emerg public health crisi antimicrobi resist sustain preval infecti diseas drive antimicrobi use industri wide suggest tradit method bolster diseas resist diseas ineffect paradigm shift approach infecti diseas control need reduc antimicrobi use sustain anim human health global economi target defens mechan promot health infect host without impact pathogen fit term diseas toler novel diseas control approach ripe discoveri articl present exampl diseas toler dictat clinic outcom sever infecti diseas human reveal evid suggest similar critic role diseas toler progress infecti diseas plagu anim agricultur thus substanti assert exploit diseas toler mechan posit impact anim human health | D000900;D003141 | T121;T047;T195 |
36,257,684 | equiti divers inclus pediatr clinician scientist canada themat analysi underrepres voic perspect miss academ clinic health scienc aim defin uniqu opportun challeng pediatr clinician scientist relat equiti divers inclus identifi key compon train need support peopl equiti seek group emerg earli career pediatr clinician scientist generat divers health research leader knowledg generat implement translat | D010820;D063505 | T054;T097 |
36,257,683 | determin guidelin concord breast cancer screen famili physician women age year qualit analysi although current canadian task forc prevent health care guidelin recommend physician inform women age year potenti benefit harm screen mammographi support individu decis previous report variat clinic practic physician level suggest lack guidelin concord care explor determin barrier facilit guidelin concord care famili physician regard screen mammographi age group | D010821;D001943 | T191;T097 |
36,257,676 | comparison laboratori method detect neoplast plasma cell plasma cell dyscrasia compar abil immunohistochemistri ihc multiparamet flow cytometri mfc fluoresc situ hybridis fish detect clonal plasma cell also attempt outlin test strategi monitor multipl myeloma patient | D010950;D009101 | T191;T025 |
36,257,619 | evalu complet sniffin stick test versus subtest differenti parkinson diseas patient healthi control hyposmia one common well first nonmotor condit parkinson diseas pd sniffin stick test sst evalu three differ aspect olfactori function threshold discrimin identif sum score three subtest produc global score olfact threshold discrimin identif tdi score | D010300;D000857 | T033;T047 |
36,257,618 | consensus brazilian headach societi sbce prophylact treatment episod migrain part ii migrain affect billion peopl worldwid million brazilian besid underdiagnos undertr disord | D008881 | T047 |
36,257,608 | physic activ measur pedomet peri urban mozambican popul studi perform describ physic activ behavior demograph associ peri urban popul mozambiqu use devic base data | D015444;D056044 | T061;T060;T056 |
36,257,595 | gut microbiota manipul epilepsi treatment mani studi document import role gut microbiota gm regul sever central nervous system cns process microbiota gut brain mgb axi latter repres connect cns enter nervous system gut microbiota sever ascend descend pathway variat gm composit associ pathogenesi andor progress well sever various neuropsychiatricneurolog diseas depress autism spectrum disord multipl sclerosi parkinson alzheim diseas recent chang bacteri composit gm also link epilepsi seizur studi explor potenti role gm regul neuron hyperexcit seizur occurr epileptogenesi accord potenti novel treatment current investig probiot prebiot symbiot may repres innov therapeut approach aim review explor effect gut microbiota manipul therapeut strategi epilepsi methodolog challeng design translat clinic trial investig gut microbiota | D000069196;D000067877;D019936;D004827 | T007;T033;T047;T001;T048 |
36,257,565 | second generat anticoagul rodenticid blood oblig facult european avian scaveng widespread use second generat anticoagul rodenticid sgar high persist anim tissu led compound becom ubiquit rodent predat scaveng food web exposur sgar usual investig wildlif speci found dead despit grow evid potenti risk secondari poison predat scaveng current worldwid exposur free live scaveng bird sgar remain scarc investig present first activ monitor blood sgar concentr preval four european oblig ie vultur facult red black kite avian scaveng ne spain analys free live bird detect sgar n individu sgar preval concentr sgar relat age forag behaviour speci studi black kite show highest preval follow red kite egyptian beard griffon ciner vultur overal preval averag sgar higher non nestl nestl speci kite egyptian vultur forag anthrop landscap eg landfil site livestock farm exploit smallmedium size carrion brodifacoum preval follow difenacoum flocoumafen bromadiolon sgar posit bird sgar mean se ng ml highest level detect ng ml abund diastereom form tran bromadiolon flocoumafen cis brodifacoum difenacoum show lower impact formul could reduc secondari exposur non target speci find suggest sgar bioaccumul scaveng bird show potenti risk avian scaveng guild europ elsewher highlight need studi potenti advers effect associ concentr sgarss blood better interpret activ monitor studi free live bird | D012378;D046093 | T131;T012 |
36,257,564 | microbiom abund environ remodel intestin microbiota improv resist obes induc chlorpyrifo mice grow consensus appropri microbiom abund environ actuat microbiota chang influenc human health whether live environ react threat contamin under mechan remain larg unknown therefor construct microbiom abund environ model focus regulatori effect obes induc exogen chemic chlorpyrifo cpf relat mechan result uncov construct farm woodland microbiom abund environ could protect mice cpf induc obes effect microbiom abund environ regul cpf induc microbiota imbal character increas lactobacillus abund alter microbiota modifi intestin immun system increas express foxp il mitig intestin barrier injuri upregul express il intestin tight junction protein fecal microbiota transplant could receiv similar phenotyp allevi cpf induc obes develop result demonstr microbiom abund environ attenu exogen chemic induc health risk remodel intestin microbiota improv intestin ecosystem prevent intestin epitheli leakag | D004390;D000069196 | T131;T007;T001;T109 |
36,257,563 | particul matter exposur exacerb cellular damag increas stress granul format respiratori syncyti virus infect human lung organoid exposur atmospher particul matter pm increas morbid mortal respiratori diseas caus various advers health effect howev effect pm exposur cellular stress virus infect condit remain unclear effect pm pm diesel pm dpm respiratori syncyti virus rsv infect investig human two dimension lung epitheli cell human three dimension lung organoid mimick lung tissu evalu format stress granul import cellular adapt various stress condit furthermor investig effect repeat exposur pm dpm dna damag cell death viral infect pm dpm caus stress granul format absenc rsv infect drastic increas stress granul format signal transduct rsv infect human lung epitheli cell human lung organoid repeat exposur pm dpm caus cell death sever damag dna rsv infect condit thus pm dpm induc sever lung toxic stress condit viral infect suggest effect pms various stress condit examin accur predict lung toxic pm | D018357;D011024 | T047 |
36,257,562 | chang heart rate variabl healthi subject short expos print shop particl effect air purifi intervent particul matter pm releas printer may caus airway inflamm cardiac electrophysiolog chang conduct two stage crossov studi examin associ short term exposur print shop particl psps heart rate variabl hrv among healthi volunt well evalu effect air purifi intervent site assess psps individu hrv paramet volunt use analyz influenc size fraction psps air purifi intervent hrv differ lag time psps exposur min min min min use linear mix effect model observ chang hrv paramet associ particl mass concentr pmc psps chang hrv paramet associ particl number concentr pnc psps sensit hrv paramet squar root mean sum squar differ adjac nn interv rmssd nn count divid total number nn interv pnn normal high frequenc power nhf high frequenc power vhf normal low frequenc power nlf ratio low frequenc power high frequenc power lfhf hrv paramet exhibit strongest effect associ pmc pnc lag time min air purifi intervent mark reduc pnc pmc size fraction psps enhanc hrv paramet decreas nlf lfhf studi suggest short term exposur psps affect hrv paramet reflect chang cardiac autonom nervous activ use air purifi reduc concentr psps improv autonom nervous system activ expos individu | D061808 | T073 |
36,257,551 | interact toxic ingest nanoparticl intestin barrier gastrointestin tract repres one primari rout entri mani nanomateri size nanomet rang high surfac area confer interest properti food addit use textur opacifi anticak agent food packag contain nanomateri antimicrobi properti human also oral expos nanoparticl nps present air drink water ingest nps reach intestin lumen interact gastrointestin fluid microbiota mucus layer epitheli barrier allow potenti transloc toxicolog profil ingest nps still unclear due varieti term composit physicochem properti well limit number investig uniqu properti relat small size could howev affect intestin ecosystem also physic function properti intestin barrier review focus fate ingest organ inorgan nps intestin lumen toxic microbiota epitheli cell | D053758;D049329 | T073 |
36,257,526 | perform mechan azo dye degrad greenhous gase reduct singl chamber electroact construct wetland system singl chamber microbi fuel cell microbi electrolyt cell novel construct wetland system propos synergist degrad congo red reduct emiss greenhous gase close circuit system show higher chemic oxygen demand congo red remov effici averag respect tradit construct wetland could also signific reduc emiss ch n co equival increas electron transfer microbi communiti analysi demonstr progress enrich dye degrad microorgan comamona electroact bacteria tolumona trichococcus denitrifi microorgan dechloromona promot pollut remov electron transfer base gene abund xenobiot biodegrad congo red biodegrad pathway describ congo red naphthalen alcohol co h summari singl chamber close circuit system could signific improv degrad congo red reduc emiss greenhous gase influenc electron transfer microbi activ | D000074382 | T197 |
36,257,525 | improv green hydrogen product chlorella vulgari via formic acid mediat hydrotherm carbonis neural network model studi investig formic acid mediat hydrotherm carbonis htc microalga biomass enhanc green hydrogen product effect combin sever factor csf feedstock suspens ratio fsr examin htc gas format hydrochar yield qualiti composit liquid phase hydrotherm convers chlorella vulgari investig csf fsr rang wt wt artifici neural network ann develop base experiment data model analys htc process result show green hydrogen format increas mol kg appli csf wt fsr reaction condit develop ann model br describ hydrotherm process high test train perform mse z e e accuraci r r enhanc h yield indic effect altern green hydrogen product scenario low temperatur use high moistur contain biomass feedstock | D048408 | T002 |
36,257,522 | achiev mainstream anammox biolog aerat filter regul bacteria communiti structur although mainstream partial nitrif anammox pn high effici sustain wastewat treatment process difficult achiev stabil due competit among function bacteria studi achiev one stage mainstream anammox via regul bacteria communiti structur studi lab scale biolog aerat filter baf result show high free ammonia mgl nitrit nitrogen n competit anammox bacteria anaob nitrit oxid bacteria nob backwash regul bacteria communiti structur backwash candidatus kuenenia becam domin bacteria relat abund increas baf one stage mainstream anammox total nitrogen tn lower mgl effluent achiev use lag time bacteria activ recoveri caus altern oper high low ammonia nitrogen nh n great potenti appli municip wastewat treatment plant mwwtps | D058440;D009573 | T123;T197;T121;T067 |
36,257,521 | integr biohydrogen biomethan produc bioprocess comprehens product biohythan product biohythan combin energi dens hydrogen methan anaerob digest low cost organ wast attract attent potenti candid transit sustain circular economi substanti research initi upscal process engin establish hythan base economi address major challeng associ process product upgrad review provid overview feasibl biohythan product various anaerob digest system singl stage dual stage possibl technolog upgrad biohythan hydrogen enrich renew natur gas main goal review promot research biohythan product technolog outlin critic need includ meta omic metabol engin approach advanc biohythan product technolog | D019149;D008697 | T074;T109 |
36,257,464 | systemat review mechanist studi relationship pesticid exposur cancer induct pesticid toxic biolog substanc use mitig harm pest applic agricultur field home increas environment pollut studi show harm effect human health specif children vulner adult intern agenc research cancer iarc introduc sever pesticid carcinogen studi aim systemat summar review studi relat pesticid cancer | D010575;D006843;D009369 | T131;T191;T109 |
36,257,463 | within versus group design time onset puberti influenc sex age differ intak palat food rat understand normat develop sensit palat food adolesc key develop anim model preclin research disord reward system eg eat disord nevertheless studi investig chang consumpt palat food sex role time onset puberti factor test multipl age adolesc femal male long evan rat use within group group test paradigm compar effect repeat test consumpt dilut sweeten condens milk within group femal rat consum per bodi mass postnat day p declin intak thereaft male rat also highest intak per bodi mass p declin thereaft although second peak evid p intak femal greater male p except p test one age group design sex differ across age declin reach plateau p sex intak per bodi weight less group rat within group rat suggest within group design use previous studi may induc bing excess consumpt discret period time thus design may captur normat develop rather sensit intak akin behaviour sensit drug abus andor bing eat evid effect time puberti onset intak either design result show methodolog factor may compromis interpret develop sex differ intak palat food | D005247;D002032 | T055;T040;T048 |
36,257,462 | chronic lipopolysaccharid impair motiv deliv ventricl deliv peripher male rat increas neuroinflamm relat control observ major depress moreov depress disord signific elev condit increas neuroinflamm eg brain injuri parkinson diseas alzheim diseas better understand relationship neuroinflamm depress addit research need current set studi made use progress ratio pr task male rat stabl measur motiv evalu daili thus ideal suit examin potenti role chronic neuroinflamm depress like behavior lipopolysaccharid lps use induc inflammatori respons experi confirm prior acut lps administr experi sensit pr task larg effect mgkg partial effect mgkg effect mgkg experi evalu dose respons continu sc lps infus found signific elev brain cytokin day dose mgkgweek experi assess motiv continu sc infus larg mgkgweek lps dose found signific impair motiv transient decreas rate lever press ie motor deficit experi measur motiv continu icv infus gkgweek lps found signific decreas motiv without chang rate lever press ie motiv deficit togeth result suggest pr task effici evalu model chronic inflamm adapt respons chronic lps exposur even deliv central may necessit altern strategi generat long term neuroinflamm | D008070;D009042 | T078;T080;T041;T109 |
36,257,447 | anti seizur mechan midazolam valproat lm variant gaba receptor genet sequenc identifi expand number variant gaba receptor associ human epilepsi identifi new de novo variant subunit lm inhibitori gaba receptor associ seizur analysi determin pathogen variant effect anti seizur medic data demonstr variant reduc cell surfac traffick peak gaba gate current synapt current mediat variant contain receptor decay faster wild type singl receptor current show variant shorten durat receptor activ decreas receptor open time test effect anti seizur medic midazolam carbamazepin valproat found three enhanc variant receptor surfac express addit midazolam restor receptor function increas singl receptor activ period synapt current decay time toward wild type level contrast valproat increas synapt peak current event frequenc promot synapt burst studi identifi new diseas caus variant gaba receptor profil pathogen effect demonstr anti seizur drug correct function deficit | D011963;D004827 | T033;T047;T116;T192 |
36,257,409 | molecular hydrogen posit influenc later root format regul hydrogen peroxid signal although previous studi discov exogen molecular hydrogen h suppli hydrogen rich water hrw mediat later root lr develop whether endogen h influenc lr format still elus report mimick induct respons tomato seedl achiev hrw exogen hydrogen peroxid h posit control transgen arabidopsi overexpress hydrogenas gene crhyd chlamydomona reinhardtii stimul endogen hydrogen peroxid h product also mark promot lr format h h respons abolish remov endogen h moreov chang transcript pattern repres cell cycl gene auxin signal relat gene lr develop tomato transgen arabidopsi thaliana match phenotyp altern level gus transcript driven cycb promot express pin protein indic h synthesi tight link lr format achiev endogen h cell cycl regul auxin depend pathway might target result might provid refer molecular mechan under regul root morphogenesi h | D017360;D018551;D029681 | T168;T116;T002 |
36,257,399 | effect hydrochar bioga slurri reflux methan product mix anaerob digest cow manur corn straw studi aim enhanc methan product mix anaerob digest cow manur corn straw ad hydrochar bioga slurri reflux hydrochar character reveal provid attach microbi growth abund surfac function group c co c oh c n adsorpt direct interspeci electron transfer diet mediat surfac oxygen contain function group hydrochar increas methan yield experiment group ad hydrochar bioga slurri reflux highest methan bioga product higher control group respect result demonstr hydrochar bioga slurri reflux improv microorgan speci rich anaerob digest system hydrochar also improv microorgan speci uniform distanc base redund analysi show vfas ph greatest effect composit microbi communiti domin microorgan phylum level ad system bacteroidet firmicut proteobacteria addit hydrochar bioga slurri reflux signific increas speci abund methanobacterium result indic addit hydrochar bioga slurri reflux improv correspond microbi abund hydrochar enhanc redox characterist diet microorgan bioga slurri reflux also increas nutrient content anaerob digest system collect promot methan yield | D008372;D056804 | T167;T109 |
36,257,398 | dichlorophenoxyacet acid adsorpt remov algal magnet activ carbon nanocomposit present studi ferric oxid nanoparticl impregn activ carbon ulva prolifera biomass upac fe prepar employ remov dichlorophenoxyacet acid adsorpt upac fe nanocomposit character structur function properti varieti techniqu nanocomposit jag irregular surfac pore due uneven scatter fe nanoparticl wherea element analysi portray incid carbon oxygen iron xrd analysi establish crystallin amorph plane correspond iron oxid carbon phase respect ft ir analyz function group confirm integr fe nanoparticl onto nanocomposit surfac vsm xps studi uncov superparamagnet natur presenc carbon fe respect upac fe nanocomposit surfac area g size volum pore nm cm g respect indic mesopor natur suitabl nanocomposit could use adsorb adsorpt remov nanocomposit variat process paramet like ph dosag agit speed adsorpt time concentr studi adsorpt upac fe nanocomposit monolay chemisorpt owe langmuir isotherm behavior along pseudo second order kinet model maximum adsorpt capac second order rate constant valu mgg gmg min respect thermodynam analysi reveal spontan feasibl endotherm adsorpt process find confirm suitabl synthes upac fe nanocomposit use adsorb toxic herbicid wast stream | D014874;D053761;D006540 | T131;T073 |
36,257,397 | function bioinspir nanocomposit anticanc activ generat reactiv oxygen speci cancer debilit dead diseas caus uncontrol growth aberr cell popul diseas alway control tradit therapi medicin differ medicin use purpos howev medicin side effect harm healthi cell better way cure cancer diseas limit agglomer cancer cell minim growth popul destroy harm cell could achiev control function mitochondria dna cancer cell use biocompat materi tuneabl physic properti accord research ongo use nanomateri nanotechnolog medicin zinc oxid semiconductor nanoparticl display good anticanc behaviour uniqu properti biocompat good stabil environment friend owe characterist focus biolog applic drug deliveri cancer therapi present research work zinc oxid titanium dioxid nanoparticl titanium oxid zinc oxid nanocomposit success trail anti cancer activ pure zinc oxid nanoparticl zno nps titanium dioxid nanoparticl tio nps nanocomposit tio zno nps prepar co precipit techniqu structur properti investig x ray diffract confirm wurtzit structur pure zno nps morpholog nps check scan electron microscopi incid light higher energi band gap nanomateri electron excit conduct band electron generat reactiv oxygen speci ros efficaci nanomateri check expos nps human liver cancer cell hepg mtt assay describ anticanc activ via cell viabil cell viabil composit observ greater pure zno nps result show structur zno nps remain composit tio nps band gap composit intermedi individu sampl also show anticanc activ composit also less pure zno nps due reduct ros generat observ nanocomposit zno tio could effect develop treatment human liver cancer cell | D015034;D053768;D053761;D008113 | T121;T197;T191;T073 |
36,257,392 | prepar polyvinyl chlorid pvc membran blend acrylamid graft bentonit oili water treatment current work aim advanc hydrophil morpholog antifoul characterist polyvinyl chlorid pvc membran oili wastewat separ incorpor modifi bentonit surfac bentonit nanoparticl alter adopt graft method use surfac initi atom transfer radic polymer si atrp approach pvc base membran first prepar blend acrylamid graft bentonit aam g bentonit aam graft bentonit presenc bipyridyl copper bromid catalyst modifi bentonit nanoparticl studi use multipl techniqu fourier transform infrar spectroscopi ftir thermal gravimetr analysi tga sediment test field emiss scan electron microscop fe sem etc flat sheet pvc base membran prepar blend aam g bentonit use nonsolv induc phase separ nip techniqu differ method includ fe sem ftir sediment test contact angl poros antifoul properti filtrat studi pure oili water use character determin perform mix matrix membran membran perform improv presenc modifi bentonit ie aam g bentonit best result achiev pvcaam g ben ie wt aam g bentonit enhanc pure water flux lm h permeat flux lm h oil reject obtain reduc contact angl improv poros | D011143;D018508 | T057;T122;T052;T109 |
36,257,391 | role metal transport phytoremedi closer look arabidopsi pollut environ heavi metal hms recent becom global issu affect health live organ continu human activ industri urban major caus hm releas environ year two method physic chemic wide use reduc hms pollut environ howev two method ineffici expens reduc hms releas atmospher altern research tri remov hms employ hyper accumul plant method refer phytoremedi high effici cost effect eco friend phytoremedi divid five type phytostabil phytodegrad rhizofiltr phytoextract phytovolatil contribut hms remov pollut environ brassicacea famili member particular arabidopsi thaliana accumul hms contamin environ plant comprehens review focus hms pollut environ discuss phytoremedi measur requir reduc impact hms environ discuss role metal transport phytoremedi focus arabidopsi draw insight role genom edit tool enhanc phytoremedi effici review expect initi research improv phytoremedi biotechnolog approach conserv environ pollut | D017360;D012989;D019216 | T131;T196;T002 |
36,257,389 | crude oil associ heavi metal hms contamin agricultur land understand risk factor chang soil biolog properti ecolog human risk crude oil associ heavi metal hms contamin agricultur land evalu employ differ indic indic employ includ enrich factor ef contamin factor c f pollut load index pli geo accumul index geo ecolog risk index eri contamin degre c nemerow pollut index p n exposur factor exf hazard quotient hq hazard index hi besid advers effect crude oil associ hms soil biolog properti also analyz result c f ef found consist show hms decreas order contamin mn zn cr ni cu geo eri fall grade geo eri respect result pli c p n exf valu clear indic high environment risk crude oil associ hms result human health risk assess reveal maximum level hms enter bodi via ingest signific p decreas fold activ cellulas phosphatas catalas ureas dehydrogenas polyphenol oxidas peroxidas crude oil contamin soil pearson correl confirm signific negat impact hms soil biolog properti | D012989;D010578;D019216 | T131;T196;T109 |
36,257,388 | z scheme promot heterojunct photocatalyst ag agvo rgocevo improv interfaci charg transfer effici remov aqueous organ irradi led light facil hydrotherm rout follow obtain ternari composit ag agvo rgocevo situ deposit ag nanoparticl agvo nano belt situ deposit promot enhanc introduct go synthes composit demonstr remark visibl light harvest effici greater visibl region charg separ light harvest properti achiev z scheme mechan mediat rgo electron trappingschottki barrier effect ag nanoparticl reduct width space charg region time simultan increas densiti charg carrier promot led irradi photocatalyt perform decay time charg carrier prolong order impli enhanc charg separ studi extend charg trap band structur model later emphas promin z scheme mechan hole mediat degrad pathway led photocatalysi demonstr remov effici mb phenol averag aqe mb phenol ternari miner effici determin toc analysi found mb phenol system respect | D012834;D053768 | T196;T073 |
36,257,387 | explor detail spatiotempor characterist pm generat full coverag hour pm dataset sichuan basin china fine particul matter pm receiv worldwid attent due threat public health sichuan basin scb pm caus heavi health burden due high concentr popul densiti compar heavili pollut area less effort made generat full coverag pm dataset scb detail pm spatiotempor characterist remain unclear consid common exist spatiotempor autocorrel top atmospher reflect toar high coverag rate auxiliari data employ build common use random forest rf model generat accur hour pm concentr predict spatial resolut scb specif histor concentr predict spatial rf rf observ station altern spatiotempor rf ast rf spatiotempor rf st rf built grid station type predict ast rf grid without station type observ type form pm dataset loocv r rmse mae gm gm ast rfst rf respect use produc dataset spatiotempor analysi conduct detail understand spatiotempor characterist pm scb pm concentr gradual increas edg center scb spatial distribut two high concentr area center chengdu zigong observ throughout year anoth high concentr area center dazhou observ winter diurnal variat doubl peak doubl valley scb concentr high night low daytim suggest character relationship pm advers health outcom daili mean might inaccur human activ conduct daytim | D000393;D000397 | T131;T069;T080 |
36,257,386 | migrat diffus unsteadi state flow volatil organ compound activ carbon adsorpt bed revers ventil despit increas attent influenc unsteadi state volatil organ compound voc adsorpt activ carbon studi regard rare therefor studi investig migrat diffus unsteadi state voc activ carbon adsorpt bed revers ventil conduct revers clean air introduc activ carbon bed reach penetr point influenc revers ventil temperatur revers superfici gas veloc activ carbon fill height differ ventil mode adsorpt unsteadi toluen activ carbon studi experiment result show revers ventil temperatur increas c c quasi first order desorpt rate constant increas min min increas revers superfici gas veloc led higher rate constant greater revers superfici gas veloc strip capac increas observ maximum strip capac achiev revers superfici gas veloc ms differ activ carbon fill height follow revers ventil strip capac cm cm activ carbon bed account origin adsorpt capac respect studi conclud concentr toluen first increas decreas time forward ventil wherea concentr gradual decreas revers ventil | D055549 | T109 |
36,257,385 | impact pet microplast fibr pvdf ultrafiltr perform short term assess mp foul simpl complex matric wastewat treatment plant wwtps key compon captur microplast mps releas natur waterway remov effici high may achiev sub micron mps well nanoplast overlook analyt limit furthermor short mp fibr concern low captur rate well lack understand influenc purif system effici studi investig impact poli ethylen terephthal pet short nanofibr perform polyvinyliden fluorid pvdf ultrafiltr membran cross flow oper model mp fibr averag length diamet nm prepar via combin electrospin fine cut use cryomicrotom manufactur mps ad pure synthet domest wastewat concentr mgl determin impact perform pvdf ultrafiltr membran result show pet fibr attach membran disorganis manner low pore coverag water flux decreas mps pure water notic effect wastewat day filtrat addit nutrient remov effici membran alter presenc pet mps find show mp fibr signific influenc earli stage filtrat standard concentr mps wastewat treatment plant studi | D014874;D018508 | T131;T052;T057 |
36,257,384 | strengthen remov emerg contamin sfe codop activ carbon fabric mild one step thermal transform scheme thermal transform carbon materi function activ carbon ac simplifi econom eco friend strategi great potenti practic applic water purif herein sfe codop activ carbon sfe ac wt wt fe creativ fabric one synchron method physic activ carbotherm reduct sulfid solid phase form iron sulfid shell signific enhanc antioxid abil nanoscal zero valent iron nzvi dramat improv hydrophob composit meanwhil dope thiophen ac enhanc hydrophob increas specif surfac area g incorpor ac turn great strengthen dispers stabil sulfur nzvi particl compar nzvi ac ac nzvi remov capac sfe ac repres hydrophob contamin triclosan tcs increas mg g respect outperform previous report materi strong hydrophob interact weak hydrogen bond electrostat repuls respons excel remov perform tcs import improv chemic properti composit caus dope sfe greater effect tcs remov compar chang physic structur furthermor stabl sfe ac show strong anti interfer capabl except regener intrigu discoveri provid new insight design advanc sustain adsorb materi emerg contamin | D014874;D018508 | T131;T052;T057 |
36,257,383 | histon deacetylas inhibitor antidiabet agent advanc opportun loss function dysfunct cell pancrea attribut develop diabet involv alter genet epigenet signatur recent evid highlight pathophysiolog role histon deacetylas hdac type type diabet inde hdac member link critic pathogen event diabet includ redox imbal endoplasm reticulum er homeostasi perturb onset oxid stress inflamm ultim deterior cell function accumul evid highlight inhibit hdac prospect therapeut strategi sever chemic synthes small molecul investig specif abil inhibit hdac reffer hdac inibitor various experiment studi review provid insight critic pathway involv regul differ class hdac intric signal network hdac stress mediat diabet also explor exhaust sum infer various investig effici hdac inhibitor manag diabet associ complic | D003924;D050417 | T047;T025 |
36,257,382 | advanc calcium oxal calculi associ drug target kidney stone constitut diseas urinari system high incid avail stone dissolv drug treatment option mechan calcium oxal stone format still larg unclear various aspect theori initi format renal stone suggest complex multistep format process kidney stone includ supersatur nucleat growth aggreg crystal crystal retent cell adhes initi stage crystal format high concentr oxal exposur may damag renal tubular cell caus oxid stress cell may attach crystal thus support oxal induc injuri drive factor crystal precipit cellular adhes howev present although various drug target kidney stone propos evalu vitro vivo clinic drug stone dissolut rare explor moreov numer advanc renal calcium oxal stone associ target drug warrant summar could discuss may provid potenti idea option explor renal calcium oxal stone treatment target drug | D002129;D007669 | T047;T109 |
36,257,381 | galangin induc osteogen differenti human amniot mesenchym stem cell via jakstat signal pathway regul stem cell direct differenti core research topic regen medicin modul fate stem cell promis strategi precis intervent util natur small molecul compound present studi aim explor potenti pro osteogen differenti effect galangin flavonoid deriv alpinia officinarum human amniot mesenchym stem cell hamsc under molecular mechan result show galangin cytotox toward hamsc concentr less treatment galangin signific increas alkalin phosphatas alp secret calcium deposit hamsc meanwhil galangin upregul mrna protein express earli osteoblast specif marker name alp runx osx late osteoblast specif marker col opn ocn hamsc furthermor signal pathway screen studi show galangin enhanc phosphoryl janus kinas jak signal transduc activ transcript stat addit molecular dock result suggest promis interact galangin jak final treatment jak specif inhibitor ag effect revers induct osteogen differenti upregul osteoblast specif marker express activ jakstat signal induc galangin result show galangin induc osteogen differenti hamsc jakstat signal pathway could serv promis small molecular osteoinduc applic hamsc regen medicin | D010012;D059630 | T025;T042 |
36,257,366 | function character secologanin synthas like homolog gene suggest involv biosynthesi divers metabolit secoiridoid biosynthet pathway camptotheca acuminata decn assign function base homolog recent challeng frequent discoveri function diverg among homolog gene famili member enzym involv plant secondari metabol secologanin synthas sls key cyp enzym act critic biosynthesi strychno alkaloid scaffold studi fulli elucid mechan under metabol variat cyp paralog particip oxid transform secoiridoid pathway function character combin multiti strategi metabolit profil phylogenet analys biochemistri assay revers genet techniqu five caslss like homolog gene mine isol integr multi omic databas camptotheca acuminata protein sequenc structur comparison phylogenet analys confirm casl casl group sls clade casl cluster dlh clade five homolog includ two previous identifi enzymat gene thus design casla casla cadlh casl casl enzymat assay recombin protein yeast show casla casla display multi catalyt activ sls secologan acid synthas slas secoxyloganin synthas sxs addit reaction caslass enzym generat stereospecif isom secoiridoid product new product secoxyloganin observ casl third sls enzym isoform catalyz format secologanin report first time howev casx enzymat activ vitro littl physiolog impact biosynthesi camptothecin cpt camptotheca acuminata primari secondari role caslss like gene secoiridoid metabol confirm virus induc gene silenc vig plant leav effici silenc transcript downregul casla compar casla homolog result greater reduct accumul cpt within silenc plant casl bare effect content metabolit planta thus casla rather casla appear function major particip biosynthesi cpt redund function caslss like enzym consist role casla ubiquit express high level camptotheca tissu casla specif express young leav contrast casl poor express everi tissu test find demonstr homolog belong cyp gene famili function divers exhibit diverg therebi uncov expand group enzymat gene determin chemo divers iridoid pathway | D029769 | T002 |
36,257,362 | textur rheolog featur strain ph sensit chitosan imin graphen oxid composit hydrogel fast self heal natur report smart chitosan isophthalaldehyd graphen oxid cs isd go hydrogel multicompon hydrogel wit unpreced ph respons chang viscoelast stretchabl adhes self heal self adapt upon chang ph concentr cs isd authent textur rheolog analysi go provid physic crosslink antibacteri properti hydrogel take advantag dynam natur coval non coval interact tune hydrogel adhes stretchabl respons ph chang self heal hydrogel fulli investig measur thixotrop respons three cycl strain sweep real time optic imag video record techniqu record video display self heal respons within time frame min properti observ small rang ph hydrogel becom mechan strong ph becom unstabl ph lead subsequ disintegr character hydrogel carri ftir fesem tga analysi addit hydrogel reduc use nabh drug releas reduc gel appear stabl lower ph valu also reduc hydrogel may potenti use drug releas purpos low toxic | D048271;D006108 | T121;T196;T109 |
36,257,351 | pid control synchron master slave neuron fraction order neocort network model model biolog neuron way understand architectur neural network brain complex brain network includ synchron group neuron dynam behavior interact group slave master neuron neocort network unpredict challeng purpos synchron neural interact reduc synchron error chaotic slave master neuron paper use proport integr deriv pid control synchron master slave neuron fraction order neocort network model base dendrit spike frequenc adapt dsfa uncertainti unknown disturb effect purpos articl two part first implement effect previous state neuron condit fraction order differenti equat neocort network model second synchron fo neocort master slave model pid control investig connect strength complex network chaotic point view optim pid coeffici fraction order calcul use root mean squar error rmse criteria control membran voltag synchron chaotic behavior system evalu numer techniqu attractor analysi time seri diagram optim rmse valu master slave neuron occur fraction order shown synchron master slave neuron improv time eventu fulli synchron control error reduc | D019579 | T023;T024 |
36,257,347 | pattern analysi neuroimag data reveal novel insight threat learn extinct human sever decad rodent neurobiolog research identifi network brain region support pavlovian threat condit extinct focus predomin amygdala hippocampus medial prefront cortex mpfc surpris function magnet reson imag fmri studi shown inconsist evid region human undergo threat condit extinct review suggest translat neuroimag effort hinder relianc tradit univari analysi fmri wherea univari analys averag activ across voxel given region multivari pattern analys mvpa leverag inform present spatial pattern activ mvpa therefor provid sensit analysi tool translat rodent neurobiolog human neuroimag review human fmri studi use mvpa success bridg rodent model amygdala hippocampus mpfc function pavlovian learn also highlight clinic applic inform sensit multivari analys sum advoc field consid adopt varieti multivari approach help bridg cut edg research neurosci threat anxieti | D005108;D005239 | T041 |
36,257,343 | ethnopharmacolog use pharmacolog toxicolog phytochemistri progress chines crude drug process later root aconitum carmichaelii debeaux fuzi review later root aconitum carmichaelii debeaux also known fuzi chines toxic chines medicin wide use clinic practic remark effect specif use treat cardiovascular diseas rheumatoid arthriti diseas korea japan india | D031841;D002318;D004365;D000470 | T121;T123;T109;T131;T047;T002 |
36,257,342 | acut oral toxic balbc mice tridax procumben allium sativum extract didehydrofalcarinol approxim peopl develop countri depend medicin plant health care tridax procumben procumben allium sativum sativum benefici effect parasit bacteri diseas side biolog activ oxylipin didehydrofalcarinol isol procumben parasit leishmania mexicana verifi | D005737;D019659 | T168;T002 |
36,257,337 | consider perform qualiti assur outpati surgeri otorhinolaryngolog head neck surgeri germani german health polici propag expans outpati surgeri procedur initi discuss otorhinolaryngolog head neck surgeri offer opportun provid current inpati procedur outpati basi | D000556;D010036 | T061;T091 |
36,257,325 | reduc penetr modi associ hnfahnfa variant gck variant clinic unselect cohort true preval penetr monogen diseas variant often known clinic referr ascertain bias comprehens assess penetr preval pathogen variant hnfa hnfa gck account monogen diabet analyz clinic genet data clinic refer proband famili member clinic unselect individu us health system base cohort n uk popul base cohort n show one individu harbor pathogen variant one gene penetr diabet hnfa hnfa pathogen variant substanti lower clinic unselect individu compar clinic refer proband depend set popul health system cohort famili member proband hnfa relat risk diabet similar across clinic unselect cohort highlight role environmentoth genet factor surpris penetr pathogen gck variant similar across cohort highlight pathogen variant hnfa hnfa gck ultra rare popul hnfa hnfa need tailor genet interpret counsel base set pathogen monogen variant identifi gck except near complet penetr set along clinic implic diagnosi make excel candid american colleg medic genet secondari gene list | D003924 | T047 |
36,257,321 | industri genom revolut new era neuroimmunolog recent discoveri highlight import understand complex interact brain immun system health neurodegen diseas primer outlin singl cell multiom approach appli patient sampl rich metadata function organoid anim model singl cell studi facilit next big leap translat neuro immun research believ pave way reshap understand neuro immun interplay descript function broad cell type effect pathway spatial organ biomark target toward comprehens mechanist understand impetus drug discoveri therapeut breakthrough envis near futur singl cell multiom technolog along advanc immunotherapi develop becom major drive forc fulli integr resourc toolset develop therapeut agent neuroimmunolog revolution drug develop treat neurodegen diseas | D019636 | T047 |
36,257,314 | syk coordin neuroprotect microgli respons neurodegen diseas recent studi begun reveal critic role brain profession phagocyt microglia receptor control neurotox amyloid beta myelin debri accumul neurodegen diseas howev critic intracellular molecul orchestr neuroprotect function microglia remain poor understood studi find target delet syk microglia lead exacerb deposit aggrav neuropatholog cognit defect xfad mous model alzheim diseas ad disrupt syk signal ad model shown imped develop diseas associ microglia dam alter aktgsk signal restrict phagocytosi microglia convers receptor mediat activ syk limit load also found syk critic regul microgli phagocytosi dam acquisit demyelin diseas collect result broaden understand key innat immun signal molecul instruct benefici microgli function respons neurotox materi | D000544;D019636 | T047;T048 |
36,257,312 | hypnotherapi irrit bowel syndrom irrit bowel syndrom ib function disord lower digest tract base biopsychosoci model wide rang therapeut intervent deal symptom ib improv qualiti life affect context hypnotherapi particular gut direct hypnosi repres psychotherapeut intervent great empir evid efficaci | D043183;D006990 | T061;T047 |
36,257,309 | cross section studi three german hospit regard oxygen therapi characterist oxygen therapi one common appli medic german hospit rescu servic hypoxemia hyperoxemia associ complic current lack reliabl data use document surveil therapi german hospit | D010102;D010100 | T061;T123;T196;T121 |
36,257,308 | function character patient isol post capillari combin post capillari pre capillari pulmonari hypertens world confer ph recommend differenti isol postcapillari ipc combin post precapillari cpc ph accord pulmonari vascular resist alon aim studi haemodynam function character patient diagnos ipcph cpcph accord current recommend latest world symposium pulmonari hypertens ph exploratori data analysi | D006976 | T046 |
36,257,307 | complaint clinic find six month covid outpati follow univers medic center freiburg increas evid suggest patient suffer persist symptom month recoveri acut covid howev clinic phenotyp pathogenesi remain unclear present data complaint result diagnost workup patient present post covid clinic univers medic center freiburg | D000086382 | T047;T067 |
36,257,306 | valid studi mep questionnair simplifi detect exacerb chronic obstruct pulmonari diseas questionnair monitor exacerb probabl mep provid novel simpl tool assist detect semiquantit numer document exacerb ecopd daili routin prospect multi center trial involv visit patient center mep evalu compar applic exact pro questionnair real world condit popul copd patient includ studi typic copd popul demograph clinic defin mep score one posit test result found sensit specif addit mep result correl clear exact pro result qualifi mep questionnair valid tool detect ecopd longitudin character copd patient | D029424 | T047 |
36,257,304 | success late treatment orbit infantil haemangioma two teenag topic transcutan timolol maleat alon previous describ first success treatment deep periocular subsequ orbit infantil haemangioma ih topic transcutan timolol maleat tm alon first line treatment acut prolif phase infanc known whether orbit ih persist proptosi later year untreat infanc would still respond tm treatment well best knowledg present first report success late treatment persist orbit ih topic timolol maleat appli skin over orbit ih two teenag case year old girl proptosi measur mm mm valsalva manoeuvr diminish mm topic treatment case year old girl mm mm proptosi valsalva decreas mm proptosi topic treatment time resolut month case month case treatment dose drop tm appli averag case two time daili case comparison proptosi resolut periorbit swell requir less treatment time recurr either proptosi periorbit swell year stop treatment either case find indic beta blocker effect prolif also late involut phase older children advers clinic effect note throughout treatment either case presenc increas proptosi valsalva manoeuvr predict signific persist vascular compart orbit ih may thus serv simpl predict clinic sign like treatment success recommend trial well toler treatment form consid persist case orbit ih especi presenc enhanc proptosi valsalva manoeuvr | D012878;D018324;D005094 | T047;T191 |
36,257,303 | linger fusion adapt influenc bielschowski head tilt test superior obliqu paresi lack posit bielschowski head tilt test bhtt common seen indic superior obliqu paresi sop present studi investig influenc fusion bhtt unilater sop | D009801;D013285 | T023;T047 |
36,257,302 | disconjugaci eye movement attempt fixat suffici marker amblyopia investig whether detect disconjugaci eye movement attempt fixat interocular posit instabl may serv singl sensit test amblyopia | D000550 | T047 |
36,257,297 | advanc glycat end product bone health diabet mellitus advanc glycat end product age compound result non enzymat glycosyl reduc sugar protein deriv food produc de novo time endogen exogen age accumul various organ liver kidney muscl bone threaten human health among organ bone wide report age accumul bone reduc bone strength particip bone structur format break bone homeostasi bind receptor alter prolifer differenti apoptosi cell involv bone remodel review summar research effect age bone health highlight associ bone health diabet patient provid clue toward discoveri new treatment prevent strategi bone relat diseas caus age | D017127;D003920 | T123;T047;T109 |
36,257,275 | rapid dilut shoot lc msms method quantifi thc cooh thc coo gluc urin cannabi remain one common use psychotrop cannabi use frequent evalu via test suspect patient sampl thus high demand simpl accur fast assay support increas need test report highlight reliabl simpl fast liquid chromatographi tandem mass spectrometri assay quantifi cannabi metabolit thc cooh thc coo gluc human urin assay employ direct dilut shoot approach wherebi urin sampl dilut x direct inject liquid chromatographi mass spectromet assay quantif base intern calibr approach use deuter analogu thc cooh thc coo gluc intern standard assay analysi time min quantif valid wide linear rang ngml analyt free matrix interfer within day day precis determin cv analyt assay valid base colleg american pathologist cap clinic laboratori standard institut clsi guidelin | D001826;D006213 | T121;T131;T031 |
36,257,260 | microvesicl inspir oxygen deliv nanosystem potenti radiotherapi mediat modul tumor stroma antitumor immun efficaci radiotherapi great challeng intens hypoxia intric stroma suppress immun microenviron tumor herein ration design microvesicl inspir oxygen deliv polyfluorocarbon nanosystem load diic halofuginon fdh promin capac improv tumor oxygen intratumor distribut synerg radiat disrupt tumor stroma boost antitumor immun combin cancer therapi fdh produc fold enhanc tumor oxygen caus effici product reactiv oxygen speci ros upon radiat fdh x ray treatment result notabl dna damag elimin cancer associ fibroblast caf major compon extracellular matrix signific enhanc tumoricid cd cd cell profound elimin suppress immun cell tumor therapeut benefit fdh x ray suppress tumor growth confirm two murin tumor model therefor studi provid encourag microvesicl inspir strategi target cancer cell caf tumor synerg radiotherapi effect cancer treatment | D009369;D000072645 | T191;T025 |
36,257,242 | feasibl valid reliabl strain measur iliotibi band isol muscular contract iliotibi band itb uniqu anatom structur transmit forc two seri muscl across later knee littl known forc transmit via itb strain respons muscl activ develop techniqu measur strain distal itb isol contract tensor fascia lata tfl muscl use kanad luca tomasi ultrasound imag track algorithm report valid method track itb tissu displac reliabl track itb strain across multipl contract intra probe placement track attempt intra oper data collect session inter probe placement track oper inter oper feasibl approach assess differ strain produc differ tfl contract level method valid track itb displac could use determin tissu strain due isol muscl contract method reliabl singl oper track trial without replac ultrasound transduc averag across multipl stimul method also abl detect chang itb strain result differ level muscl activ futur method could use assess factor like postur itb region affect strain found distal itb | D009119;D007719 | T039;T067;T030 |
36,257,240 | broken patient physiotherapist live experi incivil within healthcar team interpret phenomenolog analysi incivil healthcar team wide recognis phenomenon impact incivil far reach consequ healthcar organis individu patient care date littl research effect incivil physiotherapist extant literatur focuss nurs physician | D059825;D000075282 | T054;T097 |
36,257,238 | femor neck structur properti alter adult type diabet determin differ hip geometri adult type diabet td compar healthi adult without diabet | D005272;D003922 | T023;T047 |
36,257,185 | hydroquinon deriv attenu biofilm format virul factor product vibrio spp gram negat vibrio parahaemolyticus halophil human pathogen known lead caus food poison associ consum uncook undercook seafood increas presenc contamin seafood caus serious safeti concern food facil notabl form biofilm food surfac confer resist antimicrobi treatment therefor present studi antibacteri antibiofilm antivirul activ hydroquinon hq deriv investig v parahaemolyticus v harveyi repres activ antibacteri antibiofilm compound dimethylhydroquinon dmhq ditert butylhydroquinon dbhq examin use crystal violet assay biochem reaction live cell imag scan electron microscopi dmhq minimum inhibitori concentr mic gml complet inhibit biofilm format sub mic gml dbhq mic gml reduc biofilm format sub mic gml dmhq dbhq inhibit proteas indol product well motil phenotyp dmhq decreas fimbria product hydrophob wherea dbhq transcriptom studi reveal gene relat biofilm quorum sens qs hemolysin downregul addit dmhq dbhq prevent biofilm format v parahaemolyticus squid surfac dmhq reduc presenc v parahaemolyticus boil shrimp model toxic assay use caenorhabd elegan seed germin model show non mild toxic result suggest dmhq dbhq possess antimicrobi properti requir control v parahaemolyticus plankton biofilm state food product facil | D037521;D014736 | T123;T007;T131;T109 |
36,257,184 | heat temperatur water activ alfalfa seed affect thermal inactiv salmonella maintain seed viabil sprout involv mani outbreak salmonellosi seed identifi like sourc contamin studi aim develop effect heat treatment could achiev log reduct salmonella inocul alfalfa seed maintain seed viabil vigor effect seed water activ w heat treatment temperatur salmonella inactiv seed viabil determin alfalfa seed dip inocul four strain salmonella cocktail dri w inocul seed place seal glass tube heat c h increas w seed great improv thermal inactiv salmonella exampl achiev log reduct salmonella seed treatment time h c requir w respect treatment temperatur also great affect inactiv salmonella alfalfa seed exampl achiev log reduct salmonella seed w treatment time h requir temperatur c respect seed w critic preserv seed viabil seed treat c h increas w decreas sprout yield ratio treatment seed w c found optimum achiev desir salmonella inactiv level maintain seed viabil result log reduct salmonella yield ratio h treatment respect optimum heat treatment compar tradit ppm chlorin wash term salmonella inactiv preserv seed viabil found far superior disinfect method chlorin treatment achiev log reduct salmonella yield ratio min treatment respect | D000455;D014867 | T121;T197;T002 |
36,257,183 | effect citral nanoemuls inactiv listeria monocytogen sensori properti fresh cut melon papaya storag studi evalu surviv listeria monocytogen fresh cut melon papaya treat citral nanoemuls cn day storag c cn prepar catastroph phase invers fresh cut melon papaya artifici inocul result log cfug l monocytogen treat cn cn lml cn cn present droplet size nm monodispers distribut negat surfac charg cn reduc l monocytogen count effici count detect limit log cfug fruit h c h c c c l monocytogen count detect limit cn h papaya surviv treatment day cn cn decreas indigen microbiota scan electron microscopi sem show bubbl l monocytogen membran cell disrupt fruit treat cn final cn treat melon papaya show greater bright herbal flavor aroma firm juici well lower sugar organ acid profil chang control sampl storag result indic citral nanoemuls effici control l monocytogen growth fresh cut melon papaya store refriger temperatur without negat influenc sensori paramet | D008089;D029441;D019662 | T168;T007;T002 |
36,257,172 | develop biomimet triazin base affin ligand effici immunoglobulin g purif human rabbit plasma immunoglobulin purif differ biolog fluid consid one critic step antibodi product diagnost therapeut research purpos current studi aim elucid role differ aryl substitu triazin base affin ligand perform affin chromatographi purif media separ immunoglobulin g igg biomimet triazin base affin ligand chosen vari contain fix spacer support sepharos bead activ epichlorohydrin five type aryl substitu replac triazin ring coval immobil resin surfac diaminobutan spacer affin resin various ligand character valid use ftir sem edx microscop imag find reveal use r aminophenol r aminophenol substitu triazin ring affin ligand attach sepharos surfac atom linker cae b cl r maf r maf lead better purif igg human rabbit plasma mgml resin bind capac yield puriti result confirm design triazin base affin ligand could effect purifi igg compat fast low cost approach | D007074;D014227 | T129;T121;T116;T109 |
36,257,160 | chang algal organ matter differ dissolv oxygen pressur condit relat disinfect product format potenti metalimnet oxygen minimum reservoir lake form metalimnet oxygen minimum mom character substanti fraction dissolv oxygen deplet epilimnion effect intracellular organ matter iom algal cell transform mom condit complet differ origin iom water qualiti studi iom chang microcyst aeruginosa differ mom condit relat disinfect product format potenti dbpfps investig chang pressur concentr mom total fmax increas slight decreas differ pressur condit final decreas aerob condit dissolv organ carbon doc total fmax decreas signific decreas within first day result specif uv absorb suva uv uv indic aromat compound averag molecular weight iom gradual increas differ mom condit total dbpfps increas first decreas differ pressur condit final decreas decreas total dbpfps signific higher aerob condit anox condit final decreas redund analysi show fluoresc paramet protein like humic like fluoresc could expect index predict dbpfps moreov result reveal decreas activ divers natur microbi consortium decreas prevent degrad util organ matter natur microbi consortium therefor lower key player deterior water qualiti mom condit | D018508;D014874 | T131;T052;T057 |
36,257,159 | valid assess michigan propos qpcr threshold valu rapid water qualiti monitor e coli contamin michigan water qualiti standard specifi e coli concentr bath beach must exceed e coli per ml determin geometr mean cultur base concentr three repres sampl given beach given day cultur base analysi requir h complet result avail day sampl one day delay problemat result use prevent recreat beach unsaf sampl day reliabl indic whether recreat prevent next day due high day variabl e coli concentr demonstr previous studi contrast qpcr base e coli concentr obtain h make day beach notif decis possibl michigan propos qpcr threshold valu qtv e coli log gene copi per reaction potenti equival valu state standard base statist analysi set state wide train data main purpos present studi assess valid propos qtv determin whether impli qpcr base beach notif decis agre well cultur base decis two set test data sampl sampl whether perform propos qtv similar test train data result show perform michigan propos qtv set test data consist good eg agreement cultur base beach notif decis good better perform train data set fals negat rate propos qtv mean beach notif decis base qtv would expect permit recreat day sampl case beach exceed state standard fib contamin fals negat rate higher one would hope see well correspond error rate cultur base decis permit recreat beach exceed state standard day sampl case one day delay obtain result key advantag qpcr base analysi permit larg percentag unsaf beach identifi time prevent recreat day sampl | D004926;D014867 | T121;T197;T007 |
36,257,158 | discoveri new genus anaerob ammonium oxid bacteria mechan oxygen toler past year major stride understand core mechan anaerob ammonium oxid anammox bacteria still sever discuss point surviv strategi discov new genus anammox bacteria full scale wastewat treat biofilm system tentat name candidatus loosdrechtia aerotoleran next gene core anammox metabol encod transcrib gene involv dissimilatori nitrat reduct ammonium dnra coupl oxid small organ acid could use replenish ammonium sustain metabol surpris uniqu harbor new ferredoxin depend nitrat reductas yet found anammox genom might confer select advantag nitrat assimil similar mani microorgan superoxid dismutas catalas relat oxid stress resist encod transcrib ca loosdrechtia aerotoleran interest bilirubin oxidas bod like involv oxygen resist anammox bacteria fluctuat oxygen concentr identifi ca loosdrechtia aerotoleran four ca brocadia genom activ demonstr use purifi heterolog express protein follow survey oxygen activ protein anammox bacteria reveal presenc previous undetect oxygen defens system novel cbb type cytochrom c oxidas bifunct catalas peroxidas may confer select advantag ca kuenenia ca scalindua face frequent chang oxygen concentr discoveri new genus signific broaden understand ecophysiolog anammox bacteria furthermor divers oxygen toler strategi employ distinct anammox bacteria advanc understand nich adapt provid valuabl insight oper anammox base wastewat treatment system | D064751 | T104;T197 |
36,257,157 | quick test method predict adsorpt organ micropollut activ carbon control contamin water cycl organ micropollut omp target mani region adsorpt activ carbon effect technolog remov omp differ water matric effici design oper adsorpt process adsorpt omp proper assess usual time consum batch adsorpt test sophist analys studi quick adsorpt test method develop load powder activ carbon pac syring filter use subsequ filtrat water sampl short time treat wastewat appli compar quick test method convent batch test regard adsorpt frequent detect omp abat uv chang fraction dissolv organ matter dom similar adsorpt pattern individu omp total omp dom fraction found two method uv predict remov total omp individu omp method abat uv remov omp determin quick test led high accur predict omp adsorpt convent adsorpt test novel quick test method thus could help oper research quick monitor adsorpt capac pac product | D018508;D014874 | T131;T052;T057 |
36,257,155 | integr mfc reduc ch n nh emiss batch fed wetland system combin microbi fuel cell mfcs construct wetland cws enhanc water purif effici generat bioelectr attract extens attent howev benefit mfc cws seldom report especi potenti control gaseous emiss studi quantit compar pollut remov effici emiss multipl gase mfc cws batch fed wetland system bf cws mfc cws exhibit signific p higher cod nh n tn tp remov effici signific p lower global warm potenti gwp bf cws integr mfc decreas gwp due reduct ch n flux wherea co flux slight promot quantit pcr result indic reduc n flux mfc cws driven reduc transcript nosz gene enhanc ratio nosz nir nirk reduc ch flux relat poma mcra addit nh flux reduc mfc cws compar bf cws integr mfc promot divers microbi communiti especi anaerolineacea saprospiracea clostridiacea studi highlight benefit mfc cws provid new strategi simultan remov pollut abat multipl gas emiss bf cws | D001674;D018508 | T074;T052;T073;T057 |
36,257,154 | enhanc coagul oxid mn vii fe iii peroxymonosulf process perform mechan improv perform convent coagul process permangan mn vii pre oxid combin fe iii peroxymonosulf pms coagul process mn vii fe iii pms signific improv remov dissolv organ carbon doc turbid micropollut propos studi compar convent fe iii coagul mn vii fe iii pms process also signific enhanc remov iohexol sulfamethoxazol raw water process primari reduct product mn iv mn vii pre oxid adsorb floc surfac involv fe iii pms process natur organ matter nom raw water mediat redox cycl iron synergist effect nom fe mn facilit redox cycl mn iii mn iv fe iii fe ii promot activ pms sulfat radic play import role degrad micropollut format potenti detect volatil disinfect product dbp subsequ chlorin reduc mn vii fe iii pms process studi demonstr promis applic mn vii fe iii pms process coagul micropollut control illustr reaction mechan studi provid guidanc improv convent drink water treatment process | D005290;D018508 | T104;T052;T057 |
36,257,135 | knockdown toe caus development arrest morula blastocyst transit mice target egr protein toe evolutionarili conserv caenorhabd elegan mammal play critic role matur varieti small nuclear rnas mutat human toe report caus pontocerebellar hypoplasia type sever neurodegen syndrom howev role toe earli embryon develop remain unclear herein found toe mrna protein express mous preimplant embryo silenc toe sirna led morula blastocyst transit failur development arrest rescu toe mrna microinject edu incorpor assay show defect blastomer prolifer within development arrest embryo studi reveal toe knockdown caus increas signal hax micronuclei indic sustain dna damag moreov mrna level cell cycl inhibitor p signific upregul toe knockdown embryo development arrest togeth result suggest toe indispens mous earli embryo develop potenti maintain genom integr find provid insight role toe mous preimplant embryon develop | D001755;D047108 | T018;T039;T038;T042 |
36,257,131 | n reaction cross section calcul reactor materi nuclear reaction charg particl applic mani field radioisotop product industri applic astrophys etc therefor examin excit function perform obtain activ techniqu also import understand natur nuclear reaction also especi necessari studi reaction estim effect radiat damag fusion structur materi use construct first wall core reactor studi cross section data calcul theoret sc n ti cu n zn n zr mo n tc reaction rang mev energi via aliceash tali empir nuclear reaction code optic model paramet omp calcul deuteron induc reaction result perform via tali code calcul cross section valu reproduc well also empir develop n cross section formula kavun calcul perform mev energi final experiment exfor data compar result found compat | D011868 | T196 |
36,257,130 | sedimentari environment condit al rassafeh badyieh area syria aerial gamma ray spectrometri multifract techniqu interpret aerial gamma ray spectrometri term geolog environment analysi undertaken herein appli specif methodolog includ differ radioact statist techniqu character sedimentari environment condit al rassafeh badyieh area syria radioact techniqu use uranium favor index u alter f paramet evalu analyz relationship eu eth k ratio etheu euek ethek nine score litholog unit alreadi determin studi area statist techniqu appli non linear multifract approach concentr number model c n log log graph differenti differ radioact rang u f paramet radioact element distribut favor regard uranium potenti degre uranium remobil separ estim document nine score litholog unit unit show limit uranium remobil redistribut sedimentari environment condit area clarifi analyz etheu ratio marin continent environ indic studi region | D014501;D012990;D011834 | T131;T196;T059 |
36,257,125 | impact inhal fluticason propionatesalmeterol health relat qualiti life asthma network meta analysi network meta analysi nma compar fix dose twice daili fluticason propionatesalmeterol fpsal vs inhal corticosteroid ic icslong act beta agonist laba treatment includ administ use mainten reliev therapi mart regimen term improv health relat qualiti life hrqol relationship chang asthma control hrqol assess | D011788;D001249 | T078;T047 |
36,257,123 | metagenom character bacteri communiti antibiot resist gene found mass transit system seoul south korea mass transit system includ subway buse use environ studi urban microbiom vast major popul urban area use public transport microbi communiti urban environ includ human environ associ bacteria play role health pathogen transmiss studi use shotgun metagenom sequenc profil microbi communiti sampl various surfac found subway station bus stop within seoul mass transit system metagenom approach network analysi use investig broad spectrum antibiot resist gene arg co occurr pattern uncov bacteri speci sampl collect various surfac within seoul mass transit system sampl domin potenti human pathogen salmonella enterica human skin bacterium cutibacterium acn signific abund biomark detect subway station sampl associ bacteria typic found human oral caviti respiratori tract wherea biomark detect bus stop sampl associ bacteria common found soil water plant temperatur locat signific effect microbi communiti structur divers total uniqu arg subtyp identifi associ singl drug multidrug resist clinic import extens use antibiot includ aminoglycosid carbapenem glycopeptid sulfonamid reveal seoul subway station bus stop possess uniqu microbiom contain potenti human pathogen arg find provid insight refin locat specif respons reduc exposur potenti causat agent infecti diseas improv public health | D000900;D056186 | T121;T195;T091 |
36,257,122 | chang metabol syndrom burden risk coronari arteri calcif progress statin nave young adult aim investig associ metabol syndrom met coronari arteri calcium cac progress statin nave young adult | D024821;D061205;D019161;D003324 | T121;T047;T109 |
36,257,102 | interfer verbal interfer research interrel languag compon cognit make frequent use verbal interfer paradigm particip engag primari nonverb task simultan repeat non sens syllabl memori playback occupi articulatori buffer assum block intern languag use howev languag product involv differ subprocess level represent previous studi explicit investig affect occupi articulatori buffer thus current studi address question whether occupi articulatori buffer signific interfer conceptu experi speaker name simpl object fast accur three condit interfer condit verbal task run parallel secondari syllabl memorizationrecal task expect induc situat articulatori buffer temporarili hold phonolog inform speaker engag conceptu articulatori buffer occupi two control condit experi speaker perform similar complex task verbal respond visual depict action interfer condit two control condit result obtain experi suggest interfer taken togeth find suggest occupi articulatori buffer signific affect conceptu | D014705;D011939 | T055;T041 |
36,257,101 | deliber control facial express gono go task erp studi two studi investig role affect factor top process under product deliber control emot facial express neural underpin studi examin facial express joy fear disgust depend emot content visual stimuli upright face invert face emot induc pictur without face studi focus express joy disgust depend gaze direct without eye contact natur set real person stimulus hypothes automat process induc stimuli eg arous mimicri social cue like eye contact harder control facial express particular express joy compar fear disgust studi use gono go task show faster rts condit upright face eye contact respect also found faster rts express joy fear disgust studi particip show error go trial express joy express fear disgust indic wors top control express joy fear disgust erp analysi go p studi reveal larger amplitud upright face compar invert face emot induc pictur larger amplitud express joy disgust indic greater demand top control automat mimicri process activ degre specif particular facial express studi error go trial condit eye contact express joy indic mimicri could larger express high affili intent like express joy reduc mimicri negat express result indic facial express buffer automat process eg mimicri greater need top control especi express joy compar express fear disgust | D005149;D004644 | T033;T041 |
36,257,066 | therapeut activ lansoprazol metabolit hydroxi lansoprazol sulfid tripl negat breast cancer inhibit enoyl reductas fatti acid synthas fatti acid synthas fasn sole cytosol enzym respons de novo lipid synthesi overexpress cancer normal non lipogen tissu fasn target albeit inhibitor approv proton pump inhibitor ppis approv digest disord found inhibit fasn anticanc activ attempt repurpos food drug administr approv drug inde ppi usag benefit breast cancer patient increas respons rate due structur similar thought metabolit might extend anticanc effect ppis inhibit fasn test hypothesi found hydroxi lansoprazol sulfid hls end lansoprazol metabolit activ lansoprazol inhibit fasn function regul nhej repair oxid dna damag via parp surpris hls inhibit enoyl reductas wherea lansoprazol inhibit thioesteras fasn thus ppi metabolit may contribut last anticanc effect ppis inhibit fasn | D054328;D064726 | T121;T191 |
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