PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,228,227 | physiolog transcriptom analys leav gardenia jasminoid elli waterlog stress gardenia jasminoid elli chines herbal medicin medicin econom valu mechan respons waterlog stress remain unclear studi doubl pot method use simul waterlog stress gardenia jasminoid elli explor physiolog transcriptom respons mechan found signific damag gardenia jasminoid elli membran lipid stress pod play vital antioxid role kegg enrich show secondari metabolit flavonoid might also play antioxid role pro play signific osmot adjust endogen hormon regul gardenia jasminoid elli growth develop play role signal transduct among light waterlog stress delay time differenti express gene th gardenia jasminoid elli waterlog stress gene close associ proteasom endopeptidas ribosom mapk signal transduct endogen hormon signal transduct plant pathogen interact phenylpropanoid biosynthesi physiolog metabol pathway regul turnov transport protein reinforc adhes cell wall induct stomat closur allerg reaction defens reaction leaf movement other also absorb ultraviolet ray reduc generat oxygen free radic chang way energi util adjust osmot pressur plant cell | D004365;D032062 | T121;T123;T002 |
36,228,226 | element composit talang queenfish scomberoid commersonnianus lacpd relat bodi size condit factor pakistan fish thought appropri indic toxic water purpos present studi determin concentr metal na k ca mg fe cd pb zn relat bodi size condit factor scomberoid commersonnianus total sampl marin fish commersonnianus various size rang g bodi weight total length cm random collect arabian sea karachi pakistan examin element composit concentr calcium found maximum cadmium found minimum commersonnianus concentr zn show high signific p negat na ca exhibit strong posit correl fish size correl pb k mg found least signific p fish size condit factor show high signific correl p condit factor commersonnianus | D019216;D010473;D014874 | T131;T196;T013 |
36,228,225 | phytochem analysi hypoglycem potenti filago hurdwarica wall ex dc wagenitz alloxan induc diabet mice plant profound therapeut benefit econom treatment fewer side effect relat cheap cost make sourc drug protect prevent curat conduc purpos creat novel phytomedicin plant deriv medicin relat safe compar synthet medicin mani plant prove success aid treatment diabet includ filago hurdwarica wall ex dc wagenitz current investig therefor design assess phytochem antioxid antidiabet antihyperlipidem activ f hurdwarica phytochem investig antioxid activ differ extract carri use standard chemic test dpph ho scaveng assay f hurdwarica plant extract hydromethanol solut prepar soxhlet method store refriger c two day use swiss albino mice made diabet singl dose alloxan mgkg hydromethanol plant extract fraction f hurdwarica screen antidiabet activ given alloxan induc diabet mice concentr mgkg bodi weight differ group diabet mice oral day day glibenclamid also given anoth group standard drug support result dose mgkg bodi weight oral day day blood glucos level bodi weight mice measur th day studi found extract safe dose level mgkg dose respons effect chloroform extract mgkg f hurdwarica show express antihyperglycem effect also improv alter biochem paramet associ diabet ftir xrd spectra demonstr occurr phenol alcohol alken alkyl halid keton aromat compound confirm amorph natur extract gc ms spectral analysi show tentat presenc phytochem constitu chloroform extract f hurdwarica differ retent time conclud chloroform extract mgkg f hurdwarica reveal consider antioxid antihyperglycem antihyperlipidem potenti safe treat diabet relat complic | D019659;D003921 | T050;T002 |
36,228,224 | evalu inhibitori activ purif x ray crystallographi alpha amylas inhibitor phaseolus vulgari cultivar uttarakhand india present work base analysi inhibitori activ alpha amylas inhibitor select cultivar phaseolus vulgari uttarakhand fifteen sampl assess inhibitori activ alpha amylas inhibitor signific variat found differ cultivar crude extract alpha amylas inhibitor sampl pur purola shown maximum inhibitori activ crude extract cultivar shown consider variat inhibitori activ temperatur rang c c base inhibitori activ heat stabil profil alpha amylas inhibitor purifi pur cultivar purifi inhibitor found stabl even c inhibitori activ molecular weight purifi inhibitor nativ page polyacrylamid gel electrophoresi found kd consist two subunit kd kd sds page | D027805 | T168;T002 |
36,228,223 | minim intervent procedur evalu much pediatr dentist realli know field aim cross section studi evalu much pediatr dentist know noninvas micro minim invas strategi manag cari lesion decidu teeth electron questionnair sent pediatr dentist enrol region board dentistri inform collect concern characterist particip level updat knowledg noninvas micro minim invas procedur cari manag children agreement sentenc indic procedur data analyz descript bivari test seventi pediatr dentist particip result show high frequenc agreement sentenc strategi lesion cari manag sentenc select remov decay tissu fluorid toothpast ppm silver diamin fluorid sdf hall techniqu seal small dentin lesion level agreement sentenc signific relat variabl time sinc graduat degre updated area employ higher educ degre p higher score agreement toward sdf use accompani greater degre self declar updated noninvas micro minim invas procedur cari manag children rho p pediatr dentist consid updat agre sentenc recommend use fluorid toothpast erupt first tooth select remov decay tissu disagr still continu regard applic sdf arrest lesion progress seal small dentin lesion hall techniqu | D003731;D014100 | T047;T122;T033 |
36,228,222 | traumat dental injuri year old schoolchildren multicent cross section studi mexico aim studi determin preval dental trauma schoolchildren year age associ clinic sociodemograph socioeconom variabl cross section studi conduct children public elementari school four locat mexico depend variabl dental trauma dichotom without dental trauma dental trauma statist analysi multivari binari logist regress model generat stata averag age year girl preval dental trauma fall automobil accid sport highest number instanc p multivari model observ risk dental trauma increas age among boy schoolchildren decreas overjet lower dental trauma father age educ level associ dental trauma schoolchildren without health insur present dental trauma less often studi provid import inform regard associ differ sociodemograph socioeconom clinic variabl dental trauma mexican schoolchildren identifi factor associ dental trauma may support health promot opportun amelior preval dental trauma | D018677 | T037 |
36,228,221 | differ dimens oral health literaci associ social determin health brazilian adult social determin health sdh strong associ oral health outcom oral health literaci ohl potenti factor modifi associ studi evalu associ sdh ohl includ function interact dimens ohl cross section studi conduct adult recruit public dental clinic southern brazil function ohl measur use brazilian version rapid estim adult literaci dentistri breald health literaci dental scale held evalu interact ohl sdh evalu structur questionnair econom class determin base brazilian econom classif criteria statist analysi involv bivari multivari poisson regress robust varianc estim rate ratio rr confid interv ci among particip women mean age year median breald score strd quintil median held score strd quintil particip eight year school belong c econom class lower multipl regress analysi show school econom class associ breald held score incom age associ held score marit status occup associ breald score differ dimens ohl associ sdh brazilian adult aspect incorpor strategi improv ohl level individu popul | D057220;D009909;D064890 | T041;T067;T033 |
36,228,220 | religios associ caregiv percept preschool children dental health aim studi investig associ psychosoci factor percept caregiv dental health preschool children cross section analysi perform caregiv child dyad attend pediatr dentistri school clinic goinia midwest brazil data collect structur interview questionnair caregiv children dental record studi outcom caregiv percept children dental health posit negat independ psychosoci variabl religios duke univers religion index durel sens coher antonovski soc scale sociodemograph data oral health relat variabl also collect covari bivari analysi pearson chi squar test mann whitney poisson regress robust varianc perform preval negat percept bivari analysi negat percept associ cari experi report dental pain time child life adjust regress model preval caregiv negat percept children dental health time higher group low organiz religios pr ci time higher group children high cari experi pr ci conclus religios associ caregiv percept dental health preschool children undergo treatment special dental clinic regardless cari experi | D017028;D003731;D009909;D012067 | T047;T098;T078;T099;T097;T033 |
36,228,219 | salivari flow rate associ histopatholog aspect patient rheumatoid arthriti aim retrospect cross section studi verifi associ salivari flow rate sfr histopatholog aspect labial salivari gland lsg patient rheumatoid arthriti ra patient present rheumatolog diseas refer oral evalu includ studi ra sfr measur lsg biopsi perform patient exclud system condit affect sfr treat hyposaliv case without enough materi histopatholog analysi also exclud data collect questionnair oral examin rest stimul sfr lsg biopsi histopatholog reevalu carri order seek addit histopatholog aspect fifti one patient met inclus criteria mean age year women median rest stimul sfrs mlmin mlmin respect presenc lymphocyt focus fibrosi signific associ stimul sfr rest sfr odd ratio patient hyposaliv present posit lymphocyt focus confid interv ci stimul techniqu ci rest sfr medic record patient diagnos secondari sjgren syndrom conclus stimul sfr repres good screen test predict lymphocyt focus lsg patient ra repres specif test diagnos sjgren syndrom | D001172;D012469;D014987 | T047;T023 |
36,228,218 | impact first thousand day life dental cari life cours transdisciplinari approach review aim describ import first day child life golden period intervent action prevent dental cari chronic non communic diseas ncds throughout life cours highlight first day life could even import oral health first day life pregnanc first two year life health care provid identifi unhealthi lifestyl behavior determin bear mind contextu factor like socioeconom condit cultur aspect uniqu period work togeth famili identifi opportun adopt healthi habit might last throughout life expect newborn child window opportun prevent chronic ncds system oral origin overweight obes diabet cardiovascular diseas dental cari fact effect prevent dental cari pregnanc first month child life first day consid critic period work togeth famili facilit adopt healthi habit knowledg first thousand day life essenti repres crucial period implement action intervent guarante good oral general health develop persist throughout life | D003731 | T047;T033 |
36,228,216 | acut toxic regen dose find extract miconia ferruginata dc mous model duchenn muscular dystrophi duchenn muscular dystrophi dmd sever diseas cure caus genet abnorm promot progress muscl degener corticosteroid use drug treatment associ advers effect extract miconia ferruginata melastomatacea mf demonstr potent antioxid anti inflammatori potenti vitro studi use dmd model mdx determin toxic dose plant found possibl non toxic dose therapeut effect mdx group receiv intraperiton inject control group mg kg aqueous leaf extract follow singl dose acut toxic protocol observ day rang toxic extract ld determin histopatholog analysi quantif fibrosi immunohistochem analysi tissu perform result demonstr mg kg high toxic induc histopatholog chang tissu evalu mortal hour dose caus behavior chang sign toxic mf extract led reduct histopatholog chang fibrosi inflamm reduct hsp increas mcl protein dose mg kg demonstr regen tissu anti inflammatori potenti | D035322;D020388 | T047;T002 |
36,228,215 | cytotox antinocicept gastroproiltect potenti abuta selloana eichler fruit plant catarinens flora brazil studi evalu biolog activ extract abuta selloana gastroprotect potenti determin ethanolhcl indomethacin induc gastric ulcer wherea antinocicept effect evalu acet acid induc abdomin contort mice cytotox activ measur human cancer cell line u glioma mcf breast cancer nci h lung cancer radic scaveng potenti verifi preliminari phytochem analys perform phytochem screen reveal higher level phenol compound extract moreov methanol extract pulp fruit mepu peel fruit mepe branch meb leav mel scaveng dpph radic gml besid mel present gi gml test cell besid mepu mepe meb mel mgkg ip reduc abdomin contort respect mepu mepe meb mel reduc ethanolhcl indomethacin induc ulcer mgkg po conclus selloana interest biolog activ present leav promis sourc compound cytotox potenti howev studi perform confirm antitumor activ besid whole plant import sourc bioactiv compound associ gastroprotect antinocicept properti | D000897;D005638 | T121;T168;T002 |
36,228,214 | scienc communic activ research institut brazil recent expans way profession studi design analyz scienc communic activ gear toward general public undertaken brazilian research institut identifi often activ carri human financi resourc avail result suggest year increas scienc communic research institut respons wide rang activ communic public institut studi tend use tradit communic channel social media howev design communic team draw special personnel host institut although engag intens communic activ brazilian research institut still lack structur approach scienc communic | D000047;D003142 | T092;T054;T170;T097;T080 |
36,228,213 | empir semi empir chlorophyl model water qualiti assess river lake transit extrem southern brazil mirim lagoon second largest lacustrin water bodi southern brazil provid water local communiti howev alga growth water qualiti lagoon tributari river influenc nutrient increas context studi perform empir semi empir chlorophyl chl model use remot sens situ data water qualiti assess water qualiti data collect sampl locat lagoon date sentinel satellit overpass surfac reflect data deriv sencor atmospher correct method correl chl concentr best model present pearson correl coeffici mean absolut error gl low chl concentr observ northern lagoon possibl due suspend solid presenc occur left margin associ influenc land use agricultur high chl concentr associ shallow lentic area mean chl concentr predict model gl similar observ valu situ gl overal empir model develop appli tool reduc cost effort fieldwork measur understand eutroph river lake transit ecosystem | D060106;D045483 | T083;T070 |
36,228,212 | nutrit perform hepat renal function goat fed diet contain detoxifi castor cake differ stage pregnanc evalu influenc substitut soybean meal detoxifi castor cake perform digest nutrient nitrogen balanc hepat renal function pregnant goat fed diet contain detoxifi castor cake alkalin solut stage first two third final third pregnanc three diet provid one base soybean meal two base castor cake detoxifi whit calcium hydroxid sodium hydroxid goat fed detoxifi castor cake sodium hydroxid lower consumpt effect p diet stage digest dri matter nutrient goat receiv diet base soybean meal detoxifi castor cake calcium hydroxid consum larger amount nitrogen goat fed diet basi sm greater weight parturit day averag level enzym hepat renal function within normal pattern enzym relat liver metabol gamma glutamyl transferas increas final third pregnanc present studi demonstr detoxifi castor sodium hydroxid reduc consumpt goat gestat affect negat renal hepat paramet | D000821;D006041 | T015;T168 |
36,228,211 | microcrustacean rice field scientometr analysi evalu worldwid trend studi activ dormant form microcrustacean rice field potenti environ stock divers scientometr analysi web scienc scopus databas use compil studi publish public distribut year posit correl number studi year public rho identifi studi countri conduct japan itali unit state spain studi address two group microcrustacean follow focus cladocera ostracoda quantifi speci six group microcrustacean major cladocera ostracoda greatest rich microcrustacean identifi studi found itali thailand malaysia spain franc japan brazil studi center activ form microcrustacean rather dormant form found countri grow rice identifi rich microcrustacean even though artifici environ rice field high potenti store high divers microcrustacean | D033361;D012275 | T168;T002;T204 |
36,228,210 | maxiclavella praeclavella siphonostomatoida lernaeopodida new genera confirm molecular morpholog evid new genus maxiclavella propos accommod clavella simplex castro romero baeza kuroki differ clavella speci includ long narrow cephalothorax small bulla simpl armatur antenna antennul praeclavella nasali new genus speci found parasit olfactori sac isacia conceptioni praeclavella nasali could differenti clavella speci biram antenna exopod shorter endopod base cephalothorax larg lobular suborbicular project side suborbicular bulla mandibl without secondari teeth subov male bodi type male genera fit well clavella clade male type although differ mani aspect main posit buccal area orient ventral maxiclavella distal praeclavella nasali genit process present latter absent former genet distanc mtdna coi rdna support valid two new genera parasit host conceptioni also clavella branch clavellina wilson key base genera femal specimen present | D033342;D000080542 | T015;T204 |
36,228,209 | first record enchytraeid savanna tall woodland cerrado upper montan atlant forest brazil brazil consid megadivers countri soil fauna still poor known aim studi report first time abund genus composit terrestri enchytraeid enchytraeida oligochaeta savanna tall woodland cerrado pastur cerrado biom upper montan atlant forest grassland atlant forest biom enchytraeid densiti pastur cerradao averag individu per squar meter respect atlant forest grassland densiti individu per squar meter averag genus composit studi area enchytraeus hemienchytraeus found four ecosystem evalu tupidrilus fridericia found cerrado atlant forest respect achaeta absent upper montan atlant forest domin pastur guaranidrilus absent pastur predomin ecosystem | D009835 | T204 |
36,228,208 | divers phenolog voltin chironomida diptera neotrop stream studi model studi relationship tempor variat biolog phenomena environment factor essenti understand dynam communiti phenolog structur element togeth voltin relat time reproduct activ aim studi ascertain structur composit chironomid assemblag emerg pattern relat environment variabl use chironomid pupal exuvia techniqu use neotrop stream model stream present similar speci composit highest densiti pupal exuvia record spring greatest rich late summer earli autumn chironomina present greater preval throughout year oscil orthocladiina tanypodina chironomina tanypodina present emerg peak spring summer orthocladiina autumn winter rainfal photoperiod water air temperatur structur chironomid assemblag influenc emerg univoltin bivoltin multivoltin speci record speci present interspecif synchron emerg peak differ time year | D002683 | T204 |
36,228,207 | detect waterborn airborn microorgan rodent facil studi aim evalu air water contamin level identifi microb isol rodent facil locat feder univers uberlndia mina gerai brazil coloni form unit cfu per millilit use monitor water quantit cfu per cubic meter use air monitor isol coloni identifi qualit monitor due absenc specif paramet facil result analyz accord brazilian intern standard depend best suit sampl mean total number microorgan water rang cfuml number microorgan air rang cfum forti one microorgan identifi sampl obtain rodent facil potenti pathogen opportunist anim human eg corynebacterium spp conclud water air sampl contamin potenti pathogen opportunist microorgan harm rodent human basi observ specif sanitari standard suitabl facil develop control microbi contamin prevent zoonosi ensur reliabl scientif result obtain anim experi | D000391;D012377 | T015;T067 |
36,228,206 | plastic growth rate size sexual matur differ popul fiddler crab minuca vocat herbst within latitudin rang growth rate size matur decapod crustacean usual vari throughout latitud evalu whether life histori trait stabl within latitud rang environment factor constant especi temperatur end estim compar growth rate size sexual matur three popul fiddler crab minuca vocat locat latitud mangrov subtrop brazilian coast variat growth rate abdomin width femal propodus major chelip male assess allometr techniqu abdomen growth rate femal chelip growth rate male vari among three popul result differ size matur result support predict growth rate size sexual matur would remain stabl popul latitud rang differ life histori trait could consequ contrast local condit among mangrov therefor suggest crab show plastic respons local scale environment variat optim energi alloc mainten reproduct somat growth | D003386 | T204 |
36,228,205 | bivalv amarilladesma mactroid donax hanleyanus bioindic impact vehicl cassino beach southern brazil sandi beach main recreat ecosystem world enabl high ecolog impact especi benthic macrofauna inhabit sandi matrix low capac locomot cassino beach locat southern brazil intens vehicl traffic summer purpos studi evalu impact vehicl key speci amarilladesma mactroid donax hanleyanus purpos sampl perform three sector beach high impact moder impact control six period year result show lower densiti bivalv high impact sector sector period except first summer sampl predomin recruit throughout studi thus suggest two speci influenc intens vehicl traffic especi impact sector way conclud bivalv could use good indic puls disturb vehicl traffic beach result support manag plan regard use cassino beach consid ecolog aspect ecosystem addit econom cultur demand | D049872;D017753 | T082;T070;T204 |
36,228,204 | mutagen effect commerci fungicid rana catesbeiana leptodactylus latran tadpol examin mutagen effect fungicid elatus tadpol rana catesbeiana leptodactylus latran sixti four tadpol speci expos three concentr elatus gl hour carri micronucleus test mn erythrocyt nuclear abnorm ena tadpol speci other tadpol speci remain solut free elatus hour order assess abil recov damag caus fungicid signific differ mns frequenc treatment expos gl control group r catesbeiana l latran found differ treatment gl follow period without exposur contamin control group ena analyz compar two speci r catesbeiana present higher frequenc mns l latran treatment expos gl fungicid find highlight need monitor amphibian place product wide use | D005659;D009153 | T131 |
36,228,203 | differ environ differ reproduct strategi unexpect field observ harvestmen discocyrtus prospicuus laniator gonyleptida evolut reproduct strategi depend relat balanc current benefit futur cost geograph variat demograph ecolog factor potenti affect reproduct strategi alter optim cost benefit balanc studi popul harvestmen discocyrtus prospicuus inhabit environ never studi context tidal freshwat wetland made month observ male femal interact associ egg clutch two year field survey result match expect pattern speci consist male desert femal immedi copul femal lay isol egg abandon oviposit convers show first time pair prospicuus form femal male rest togeth oviposit femal wetland popul lay egg small clutch clutch egg one stage develop also found mani femal alon near egg clutch typic rest posit find mark widen behavior specter previous report speci set stage futur research determin caus variat | D001097;D012098 | T081;T040;T079;T204 |
36,228,199 | translat portugues set questionnair design evalu impact use telepres robot postop ward round use telepres grow advanc technolog integr medic practic regard surgeri effect distanc communic translat better periop care though patient percept modal need critic evalu structur questionnair use object scale instrument choic measur subject aspect howev questionnair avail portugues object thus translat adapt portugues specif questionnair evalu use telepres robot post operatori ward round | D012371 | T090 |
36,228,198 | clinic epidemiolog chang patient non traumat acut abdomen covid pandem retrospect studi intend demonstr clinic alter postop evolut patient acut abdomen non traumat conserv surgic treatment pandem compar similar period last year | D000006;D000086382 | T047;T184;T067 |
36,228,197 | learn curv semi rigid ureteroscopi small calculi mani case necessari semi rigid ureteroscopi procedur choic treatment ureterolithiasi requir learn curv perform safe | D014514;D018666 | T061;T047;T058 |
36,228,194 | potent specif activ mitochondri sirtuin sirt sirt sirtuin nad depend protein deacylas involv metabol regul age relat diseas specif activ seven human sirtuin isoform would import chemic tool potenti therapeut drug activ describ sirt act via uniqu n termin domain isoform sirtuin isoform includ mitochondri sirt potent specif activ yet identifi describ identif character dihydropyridin base compound either act pan sirtuin activ specif stimul sirt sirt activ bind sirtuin catalyt core independ nad acyl peptid stimul turnov peptid protein substrat compound also activ sirt sirt cellular system regul eg apoptosi electron transport chain result provid scaffold potent sirtuin activ deriv specif sirt sirt excel basi drug develop | D037761;D056566 | T126;T116 |
36,228,182 | origin stori rapamycin system bias biomed research cold war polit metei medic expedit easter island canadian led expedit easter island led discoveri rapamycin launch billion dollar drug industri major field biomed research stanley dream medic historian jacalyn duffin provid remark detail metei rais import time question system bias biomed studi relationship scienc geopolit well oblig pharmaceut compani indigen communiti book must read interest intersect scienc societi well anyon use rapamycin one mani deriv laboratori clinic | D035843;D020123 | T121;T062;T109;T195 |
36,228,180 | crystallograph map tune water adsorpt metal organ framework featur distinct open metal site crucial step toward design water sorption materi fine tune properti specif applic includ precis identif adsorpt site establish rigor molecular level insight water adsorpt process report stepwis crystallograph map densiti function theori comput adsorb water molecul alp mof metal organ framework decor distinct open metal site carbonyl function group serv water anchor site seed nucleat complex water network identif unusu water adsorpt step alp mof motiv tune metal ion composit adjust water uptak studi provid direct evid ident open metal site mof dramat affect water adsorpt behavior rh multipl proxim water anchor site along mof skeleton facilit water uptak could potenti use applic requir rapid energet facil water sorption | D000073396 | T109 |
36,228,179 | cautious artifici intellig improv outcom trust flag outlier case artifici intellig ai model medic imag diagnosi often train valid curat data howev clinic set imag outlier respect train data repres rare diseas condit acquir use slight differ setup lead wrong decis practic expect clinician train discount result outlier imag toward clinic deploy design method train cautious ai automat flag outlier case | D001185;D035502 | T090;T054;T066;T073 |
36,228,178 | enhanc administr claim data feasibl valid applic link medicar claim data nation marrow donor program search data administr claim data provid real world servic util acut myeloid leukemia aml treatment lack insight treatment delay barrier nation marrow donor program nmdp match search search data contain inform donor search lack inform treatment receiv allogen hematopoiet cell transplant hct perform hypothes link two data set would creat rich resourc defin factor associ receiv hct could evalu either data set alon | D018380;D015470 | T191;T061 |
36,228,175 | placent therapeut target nanodeliveri system pregnanc complic affect million women year diseas high morbid mortal preeclampsia present safe effect treatment pregnanc complic still difficult clinic problem mani pregnanc complic close relat placent dysplasia placenta specif therapi import method expect safe effect specif therapeut strategi review explain detail placenta physiolog structur characterist action mechan biomolecul signal pathway play role normal develop disord develop placenta use biomolecul therapeut target placenta disord caus diseas combin latest progress field nanodeliveri system lay foundat develop placenta specif therapi pregnanc complic | D011225;D011248 | T046 |
36,228,174 | metal nanoparticl dope oxid semiconductor film bone tumor suppress bone regener bone implant phototherm effect promis treatment bone tumor defect nobl metal base phototherm nanoag wide studi stabl phototherm effect expens difficult direct grow implant surfac contrast non nobl metal phototherm nanoag econom unstabl herein develop stabl econom phototherm film bone implant ni nanoparticl dope oxid semiconductor film grown situ nitinol via reduct ni ti layer doubl hydroxid ni nanoparticl remain stabl nitio structur even immers fluid month thus film present reliabl phototherm effect near infrar light irradi film also show excel vitro vivo antitumor perform moreov nanostructur film allow bone differenti mous embryo cell cht releas ni ion support angiogenesi behavior human vein endotheli cell bone implant experi show enhanc osteointegr modifi nitinol implant vivo novel multifunct nitinol bone implant design offer promis strategi therapi bone tumor relat defect | D001859;D053768;D053758 | T191;T073 |
36,228,172 | zwitterion polym coat antibiofoul photoelectrochem aptasensor vivo antibiot metabol monitor track long term vivo monitor track target molecul live organ essenti reveal vital physiolog activ howev undesir contamin protein biolog cell may bring serious biofoul issu herein zwitterion sulfobetain methacryl sbma polym graft tio nanotub nt surfac polydopamin pda linker fabric tio ntspdasbma photoelectrod tio ntspdasbmaaptam base pec aptasensor sensit select detect target molecul excel antibiofoul activ benefici advantag implant micro pec aptasensor implement vivo track monitor metabol antibiot live mous robust antibiofoul properti generat new inquiri approach long stand question new way reliabl long term sens vital biomolecul complex biolog fluid uncov promis advanc intrins physiolog mechan | D014025;D011108 | T104;T196;T122 |
36,228,170 | blue light mediat photocatalyst free decarboxyl alkyl heteroaryl sulfinimin report diastereoselect photocatalyst free decarboxyl alkyl hetero aryl sulfinimin use redox activ ester blue light high yield diastereoselect achiev mild condit demonstr util synthet method especi medicin chemist | D007097 | T109 |
36,228,126 | one pot synthesi diaryl diketon via zn mediat reduct coupl reduct coupl reaction establish synthesi diaryl dicarbonyl compound aryl methyl keton good yield mechanist studi show reaction undergo c co c sp bond cleavag reduct coupl reaction occur electron transfer process notabl reaction simpl oper also mild reaction condit wide rang applic substrat | D007659;D015032 | T121;T109;T123;T196 |
36,228,115 | impact cellular environ adenosin triphosph conform cytoplasm environ crowd macromolecul fill metabolit ion recent experiment comput studi address environ affect protein stabil fold kinet protein protein protein nucleic acid interact though impact metabolit remain larg unknown show simul cytoplasm affect conform adenosin triphosph atp key energi sourc regulatori metabolit present high concentr cell analysi atom model small volum escherichia coli cytoplasm contrast atp model vitro resolv protein structur deposit protein data bank reveal atp molecul bound protein cell form specif pitch conform observ signific concentr environ hypothes interact evolv fulfil function role atp interact protein surfac | D000255;D009696 | T121;T123;T114 |
36,228,111 | reconstruct surgeri treat pressur ulcer sever possibl intervent manag pressur ulcer sometim refer pressur injuri rang pressur reliev measur reposit reconstruct surgeri surgic approach usual reserv recalcitr wound heal process stall wound respond treatment wound full thick skin loss exposur deeper structur muscl fascia bone reconstruct surgeri common involv wound debrid follow fill wound new tissu whilst accept mean ulcer manag benefit harm differ surgic approach compar non surgic treatment unclear updat cochran review publish | D003668;D019651 | T061;T047 |
36,228,078 | communiti health worker trust builder healer cohort studi primari care improv patient self care chronic diseas often elus context social depriv evalu whether practic integr communiti health worker chw intervent could encourag effect long term self manag type diabet mellitus tdm | D003150;D003924 | T047;T097;T102 |
36,228,076 | racial ethnic inequ use prevent servic among privat insur adult pediatr onset disabl cerebr palsi cp spina bifida sb pediatr onset disabl adult live cpsb greater need prevent care general popul due increas risk chronic diseas object compar whiteblack whitehispan inequ use prevent servic | D001741;D003920 | T098;T047 |
36,228,075 | use state payer claim data identifi activ primari care workforc novel studi virginia primari care foundat health care workforc part extend life improv health equiti previous research geograph specialti distribut physician reli american medic associ masterfil data limit overestim workforc | D008511;D013038 | T090;T091;T078;T097 |
36,228,073 | caregiv pandem health relat socioeconom vulner among women caregiv earli covid pandem famili friend provid regular care sick depend individu caregiv increas risk health relat socioeconom vulner hrsvs studi examin pre pandem preval earli pandem chang hrsvs among women caregiv compar non caregiv | D000086382;D058873 | T047;T067 |
36,228,069 | joy grief know patient medic school resid taught alway keep boundari patient took lesson heart consid patient mere diseas train transit role earli career attend physician realiz lack meaning patient relationship concomit burnout caus henc chang perspect start listen patient stori stori give purpos gratitud medicin never felt flip side also gain insight stori come cost much joy grief exist simultan bad outcom patient loss heartbreak ever essay reflect upon journey find path humanist side medicin highlight struggl find balanc joy connect patient vulner pain loss accompani | D002055;D006117 | T041;T048 |
36,228,068 | famili physician stop practic covid pandem ontario canada conduct analys use administr data understand whether famili physician ontario canada stop work covid pandem compar previous year first found physician work n report bill first month pandem compar famili physician higher portion age year older vs p fee servic reimburs vs p panel size patient vs p second fit regress line found absolut increas percentag famili physician stop work per year p p research need understand impact physician stop work primari care attach access care | D000086382;D010821 | T047;T097;T067 |
36,228,066 | physician patient interrupt clinic practic quantit analysi physician interrupt long consid intrus masculin action inhibit patient particip systemat analysi interrupt clinic interact lack studi aim examin primari care physician patient interrupt consult | D010817;D010820 | T054;T097 |
36,228,065 | revit primari care part root caus primari care problem part essay offer discuss health primari care unit state part argu root caus primari care problem low percent nation health expenditur dedic primari care primari care spend over larg patient panel clinician without team unabl manag lead widespread burnout poor patient accessinform use essay come person clinic polici experi bolster summari evid analysi lean heavili visit dozen practic interview hundr clinician practic leader practic staffin unit state spent approxim total health expenditur primari care compar averag among organ econom co oper develop oecd countri averag us primari care panel size around would take clinician without effect team hour per day provid good care panel low primari care spend excess panel size relat medic student avoid career featur underfund practic unsustain work life balanceov past year mani initi explor part essay attempt address problem part argu revit primari care fundament chang need increas spend dedic primari care creat power team add capac care larg panel | D005102;D011320 | T058;T081 |
36,228,064 | clock draw test screen tool cognit impair associ fecal immunochem test collect error purpos studi determin certain demograph characterist potenti predictor particip clock draw test result screen test cognit impair associ fecal immunochem test fit sampl collect error | D060825;D015179 | T191;T048 |
36,228,063 | return communiti traumat grew food stamp unlik mani medic school classmat prostitut drug deal regular occurr neighborhood man shot death front childhood home left hometown final abl heal devast circumst build safer life difficult question surfac consid want work physician gain clariti chose return hometown part monthlong clinic elect experi facilit vulner introspect learn honor fact hometown place tenaci struggl beauti peopl accept experienc survivor guilt peopl agent chang live serv other owe safe heal wound first ultim decid want partak stori human inexor surviv face structur barrier | D000076783 | T033 |
36,228,061 | face god reveal mani year pass sinc visit donni hospit admit newli diagnos termin lung cancer despit year separ wife rose took back home care donni end life month death learn relationship donni drink infidel emot verbal abus rose put end one offic visit incredul silent amaz ask rose look simpli said one us famili repeat saw face god gaze well care donni rose spiritu director encourag work describ imag god arid time place interior journey activ felt forc inauthent although rose die year ago still think reflect life physician practic shadow covid pandem look uncertainti scatter imag draw stir divin wellspr | D000086382;D058873 | T047;T067 |
36,228,060 | effect facilit strategi support primari care practic chang mix method studi practic facilit evid inform implement strategi support qualiti improv qi aid practic align best evid studi particular size scope identifi strategi contribut facilit effect | D011320;D058996 | T058;T057 |
36,228,059 | revit primari care part hope futur part essay argu root caus primari care problem lie low percent nation health expenditur dedic primari care over larg patient panel clinician without team unabl manag lead widespread burnout poor patient access part explor polici practic chang could solv mitig primari care problemsin attempt improv primari care discuss diffus multi compon initi patient center medic home pcmhs account care organ aco comprehens primari care plus cpc limit success address primari care core problem focus initi care manag open access telehealth offer promiseto truli revit primari care fundament chang need substanti greater percent health expenditur dedic primari care build power team add capac care larg panel reduc burnoutpart essay review approach increas primari care spend state level legisl elimin medicar dispar primari care procedur specialti reimburs effort health system final section part address build power core interprofession team | D060866;D006278 | T093;T064;T089 |
36,228,057 | solvent effect temperatur depend hydrid kinet isotop effect correl donor acceptor distanc protein structur effect temperatur depend kinet isotop effect kie h tunnel reaction recent use discuss role enzym thermal motion catalysi frequent observ near independ kie wild type enzym depend kie variant suggest h tunnel former assist natur evolv protein construct vibrat help sampl short donor acceptor distanc dad need explan correl depend kie dad sampl high debat simul follow h tunnel model sometim gave altern explan paper solvent effect depend kie two hydrid tunnel reaction nadhnad analogu repres e e ad e ah determin attempt replic observ enzym test protein vibrat assist dad sampl concept effect select aprot solvent dad prc product reactant complex prcs dad trs activ tunnel readi state trss obtain comput analys kinet data includ kie respect weaker depend kie ie smaller e found polar aprot solvent system shorter averag dad prc dad trs result show charg transfer ct complex made stronger donoracceptor give rise smaller e overal shorter less broad distribut dad result stronger ct complex vibrat give rise smaller e result appear support explan link depend kie donor acceptor rigid enzym | D009243;D007554 | T121;T196;T123;T114 |
36,228,045 | cryo em structur lolcd reveal molecular mechan bacteri lipoprotein sort escherichia coli bacteri lipoprotein perform divers array function includ bacteri envelop biogenesi microb host interact lipoprotein gram negat bacteria sort outer membran om via local lipoprotein lol export pathway atp bind cassett abc transport lolcd initi lol pathway select extract transport lipoprotein traffick report cryo em structur lolcd apo lipoprotein bound amppnp bound state resolut structur base disulfid crosslink photo crosslink function complement assay verifi apo state structur reveal molecular detail regard substrat select substrat entri rout studi snapshot function state lolcd transport cycl provid deep insight mechan underli lolcd mediat lipoprotein sort e coli | D004926;D029968 | T007;T116 |
36,228,044 | glaesserella parasui serotyp breach porcin respiratori epitheli barrier induc autophagi block cell membran claudin replenish glaesserella parasui g parasui primari pathogen glsser diseas colon upper respiratori tract break epitheli barrier respiratori tract lead lung infect howev under mechan advers effect remain unclear g parasui serotyp sq strain hps sq infect decreas integr piglet lung occludin claudin autophagi regul function epitheli barrier tight junction protein tjs express test hypothesi hps sq break porcin respiratori epitheli barrier link autophagi claudin degrad hps sq infect swine tracheal epitheli cell stec autophagosom encapsul autolysosom degrad oxid stress mitochondria cover claudin furthermor found autophagosom encapsul mitochondria result cell membran claudin unabl replenish degrad damag respiratori tract epitheli barrier conclus g parasui serotyp break porcin respiratori epitheli barrier induc autophagi interrupt cell membran claudin replenish clarifi mechan g parasui infect provid new potenti target drug design vaccin develop | D044137;D006192;D013553 | T007;T047 |
36,228,043 | multipl immunodomin epitop co express live attenu salmonella serovar induc cross protect immun respons paratyphi typhimurium enteritidi salmonella enterica subsp enterica enterica signific public health concern estim caus death annual nowaday vaccin avail human salmonellosi prevent target one serovar ie typhi leav huge potenti risk salmonella diseas epidemiolog chang studi explor strategi multipl immunodomin epitop co express enterica serovar evalu immunogen induc cross immun respons cross protect paratyphi typhimurium enteritidi found nucleotid sugar precursor cdp abe cdp par cdp tyv could util enterica serovar simultan exhibit doubl immunodomin serotyp without obvious growth defect import tripl immunodomin serotyp could achiev typhimurium improv substrat pool cdp par glycosyltransferas wbav flippas wzx via dual plasmid overexpress system immun murin model found doubl tripl serotyp live attenu vaccin candid could induc signific higher heterolog serovar specif antibodi wild type parent strain meanwhil bacteri agglutin serum bactericid assay protect efficaci experi shown elicit serum antibodi cross reactiv cross protect work highlight potenti develop new type live attenu salmonella vaccin paratyphi typhimurium enteritidi simultan | D014436;D022562 | T121;T109;T129 |
36,228,040 | clinic prognost relev sst adult dengu associ cardiac impair sever dengu dengu complic sever outcom includ cardiac impair lack reliabl prognost biomark pose challeng manag febril dengu patient investig function solubl suppressor tumorigen sst predict marker sever dengu associ dengu associ cardiac impair | D020097;D019595 | T047;T116;T121;T123;T125 |
36,228,039 | lrrc inhibit sar cov cellular entri tran sever acut respiratori syndrom coronavirus sar cov infect mediat entri receptor angiotensin convert enzym ace although attach factor coreceptor facilit entri extens studi cellular entri factor inhibit viral entri larg unknown use surfaceom crispr activ screen identifi human lrrc inhibitori attach factor sar cov entri lrrc direct bind receptor bind domain rbd spike protein moder affin inhibit spike mediat entri analysi human lung singl cell rna sequenc dataset reveal express lrrc primarili detect fibroblast particular enrich patholog fibroblast covid patient ace lrrc coexpress cell type lung strike express lrrc ace negat cell block spike mediat viral entri ace cell tran suggest protect role lrrc physiolog context therefor lrrc repres inhibitori attach factor sar cov regul viral entri tran | D000085962;D000086382 | T067;T047;T126;T116 |
36,228,038 | perceptu distract distract target stimulus occur presenc distract decis less accur exact distract affect choic explor question use measur human behaviour psychophys revers correl comput model contrast two model one target distract independ influenc choic independ model one distract modul choic way depend similar target interact model across three experi particip ask make fine orient judgment tilt target grate present adjac irrelev distract found strong evid interact model decis sensit target distract consist relat inconsist consist bias occur frame refer decis oper decis valu rather sensori signal surpris independ spatial attent normal framework target featur normal expect variabl local context success captur observ pattern result | D001288 | T041 |
36,228,036 | orthosnap tree split prune algorithm retriev singl copi ortholog gene famili tree molecular evolut studi phylogenom studi genom wide survey select often reli gene famili singl copi ortholog sc og larg gene famili multipl homolog speci phenomenon observ among sever import famili gene transport transcript factor often ignor identifi retriev sc og nest within challeng address issu increas number marker use molecular evolut studi develop orthosnap softwar use phylogenet framework simultan split gene famili sc og prune speci specif inparalog term sc og identifi orthosnap snap og identifi use split prune procedur analog snap branch tree ortholog group gene infer across eukaryot phylogenom dataset identifi sc og use orthosnap remain ortholog group gene identifi addit snap og comparison snap og sc og reveal phylogenet inform content similar even complex dataset contain whole genom duplic complex pattern duplic loss transcriptom data gene typic multipl transcript contenti branch tree life orthosnap use increas number marker use molecular evolut data matric critic step robust infer explor tree life | D019143;D000465 | T038;T170 |
36,228,035 | compar analysi fenghuang dancong tieguanyin dahongpao tea use headspac solid phase microextract coupl gas chromatographi mass spectrometri chemometr method fenghuang dancong tieguanyin dahongpao tea belong semi ferment oolong tea famous uniqu aroma howev report regard systemat comparison differenti classif volatil compon three type oolong tea lack studi aim establish method distinguish three type oolong tea volatil compon total tea sampl three type oolong tea extract determin identifi headspac solid phase microextract hs spme combin gas chromatographi mass spectrometri gc ms addit chemometr method hierarch cluster analysi hca princip compon analysi pca orthogon partial least squar discrimin analysi opl da use distinguish classifi three type oolong tea basi similar differ volatil compon result show volatil compon extract identifi three type oolong tea among volatil compon overlap among sampl result hca indic sampl three type oolong tea could place one categori valu result pca opl da show volatil compon dehydrolinalool linalool oxid ii linalool farnesen linalool oxid ocimen nerolidol cis butyr acid folat myrcen z hexano acid hexenyl ester characterist compon use distinguish three type oolong tea develop simpl fast effici method distinguish three type oolong tea provid feasibl techniqu identif oolong tea type | D028241;D055549 | T109;T002 |
36,228,034 | role psycholog flexibl mean reconstruct process cancer intens longitudin studi protocol mean make import element adapt diseas howev process still poor understood theoret model comprehens verifi yet particular term complex dynam intraindividu variabl aim studi deeper understand mean reconstruct process cancer empir verif integr mean make model cope extend psycholog flexibl model postul psycholog flexibl foster mean make cancer build flexibl workabl mean make explan diseas | D000223;D009369 | T191;T055 |
36,228,033 | estim microbi popul data optic densiti spectrophotomet use decad measur densiti bacteri popul turbid express optic densiti od howev od alon unreli metric proportion accur cell titer od relationship od cell titer depend configur spectrophotomet length light path cultur size bacteri cell cell cultur densiti demonstr import plate reader calibr identifi exact relationship od cellsml use four bacteri genera two size micro titer plate well well show cellml per unit od depend heavili bacteri cell size plate size appli calibr curv real growth curv data conclud cellsml rather od metric use direct compar result across experi lab instrument speci | D001419 | T007 |
36,228,032 | improv diagnosi tubercul lymphaden combin cytomorpholog mpt immunostain cell block fine needl aspir extra pulmonari tuberculosi eptb constitut tuberculosi tb case tubercul lymphaden tbl constitut eptb diagnosi tbl challeng paucibacillari natur diseas | D009169;D014388 | T007;T047 |
36,228,031 | race black white sex inequ tooth loss popul base studi effect health inequ determin differ socioeconom sex race condit studi aim analyz associ tooth loss race defin self report skin color sex base hypothesi associ tooth loss race may modifi sex also aim evalu possibl interact race sex associ event popul base studi citi campina brazil direct acycl graph use select covari preval tooth loss higher black women compar white men preval ratio pr ci moreov preval tooth loss black women higher white women pr ci within strata black peopl black women higher dental loss pr ci compar black men studi found signific interact race sex tooth loss disadvantag black women addit work contribut discuss health inequ support polici provis univers dental care | D016388 | T020 |
36,228,030 | pool preval stunt associ factor among children age month sub saharan africa countri bayesian multilevel approach million children five suffer stunt respons one million death million disabl adjust life year dali five children worldwid predomin occur low middl incom countri like sub saharan africa stunt children begin live mark disadvantag poor cognit educ perform low adult wage lost product accompani excess weight gain later childhood increas risk nutrit relat chronic diseas adult life devast effect stunt last lifetim even affect next generat despit magnitud rise past year sub saharan africa studi captur pool preval associ factor stunt among children age month sub saharan africa limit therefor studi carri basi bayesian approach determin pool preval predictor stunt among children age month sub saharan africa | D006130;D009748 | T047;T046 |
36,228,029 | assess knowledg percept leishmaniasi island wide studi sri lanka cutan leishmaniasi cl notifi diseas sri lanka increas case number report everi part countri addit diseas treatment vector control measur knowledg percept communiti key contributor success intervent program island wide survey carri assess knowledg percept regard cl across island confirm cl case control data collect train personnel use pre test case report form crf although percentag refer cl correct name low major state fli induc skin diseas knowledg symptom curabl name vector high communiti specif knowledg vector breed place bite time prevent method poor patient knowledg compar control differ level knowledg could identifi accord level educ particip well across differ area countri main sourc inform healthcar system involv media educ communiti diseas minim studi popul unaccustom use repel spray use bed net high particip studi popul although misconcept incorrect practic rare sri lankan communiti promot health educ program may improv diseas awar knowledg vector control strengthen control prevent strategi | D016773 | T047 |
36,228,028 | perspect clinic pharmacist provis pharmaceut care telepharmaci servic covid pandem qatar focus group coronavirus diseas covid pandem creat unpreced pressur healthcar system led widespread adopt telepharmaci servic practic previous establish state qatar | D000086382;D003157;D010607 | T047;T058;T067;T093 |
36,228,027 | preval arbovirus infecti caus skin rash patient treat tertiari health unit brazilian amazon clinic cours diseas arbovirus skin rash may appear often seen infecti diseas aim studi estim preval arbovirus infecti caus skin rash tertiari health unit manaus amazona state western brazilian amazon | D001103;D065632;D003586;D003715;D005076;D015658;D008457;D012409;D013587;D000071244;D000071243 | T047;T184;T005 |
36,228,026 | silico function annot hypothet protein bacillus paralicheniformi strain bac reveal protein biotechnolog potenti adapt function extrem environ member bacillus genus industri cell factori due capac secret signific quantiti biomolecul industri applic bacillus paralicheniformi strain bac isol red sea share close evolutionari relationship bacillus licheniformi howev signific number protein genom annot function uncharacter hypothet protein investig protein function may help us better understand bacteria surviv extrem environment condit find novel target biotechnolog applic therefor purpos research function annot hypothet protein genom b paralicheniformi strain bac employ structur silico approach incorpor numer bioinformat tool databas function annot physicochem character subcellular local protein protein interact three dimension structur determin sequenc hypothet protein evalu abl success attribut function hypothet protein moreov perform receiv oper characterist analysi assess perform various tool use present studi identifi protein signific adapt role unfavor environ sporul format biofilm motil regul transcript etc addit protein predict biotechnolog potenti coenzym biosynthesi phenylalanin biosynthesi rare sugar biosynthesi antibiot biosynthesi bioremedi other evalu perform tool show accuraci repres ration tool use work show annot strategi make function character unknown protein easier find target investig knowledg hypothet protein potenti function aid b paralicheniformi strain bac effect creat new biotechnolog target addit result may also facilit better understand surviv mechan harsh environment condit | D001407 | T007 |
36,228,025 | differ driver mental social function financi well covid evid australia franc germani south africa covid substanti unexpect impact individu daili life around world unpreced public health restrict lockdown potenti affect multipl dimens individu well sever restrict vari across countri howev holist perspect compar differ driver differ dimens well across countri differenti affect covid miss date address gap literatur examin mental social function financi well individu across australia franc germani south africa mean survey administ may support holist approach find differ dimens well correl survey respond franc report lowest australia report highest overal level well respond subject object evalu live condit lockdown well posit health financi behavior posit associ well pandem | D000086382 | T047;T067 |
36,228,024 | individu differ disson arousalreduct relat physic exercis test action base model present research design test predict deriv action base model cognit disson theori predict disson arous would negat relat effect behavior disson reduct would posit relat effect behavior | D003073;D007206 | T054;T041 |
36,228,023 | impact earli life shock educ pursuit fade co exist persist chang climat condit increas variabl rainfal pattern worldwid negat rainfal shock face children initi day life result malnutrit harm likelihood children surviv overal growth develop brain motor skill cognit abil lead poor perform educ labor market exist find long run outcom mix essenti understand nuanc estim | D044342 | T047 |
36,228,022 | conflict fertil under transient evolut reinforc two speci meet secondari contact product low fit hybrid may prevent adapt evolut increas prezygot isol process known reinforc theoret challeng evolut reinforc general cast coordin problem ie statist associ trait prefer maintain face recombin howev evolut reinforc also pose potenti conflict mate exampl opportun cost hybrid may differ sex speci particular like reinforc base postmat prezygot pmpz incompat abil fertil conspecif heterospecif egg benefici male gamet heterospecif mate may incur cost femal gamet develop popul genet model interspecif conflict reinforc inspir gametophyt factor act pmpz barrier among zea may subspeci demonstr conflict result transient evolut reinforc femal adapt evolv reject gamet lack signal common conspecif gamet gamet signal adapt introgress popul ultim male gamet signal fix speci isol return pre reinforc level interpret geograph pattern isol among z may subspeci consid find suggest conflict resolv result suggest sexual conflict fertil may pose understudi obstacl evolut reinforc | D006824;D012098 | T045;T081;T040;T079 |
36,228,021 | inequ matern healthcar use sierra leon evid demograph health survey sierra leon one countri poor health outcom countri made progress uptak matern health servic despit improv nation coverag rate evid equal improv | D008427 | T058 |
36,228,020 | rememb harm advocaci group america frontlin doctor appear step unit state suprem court fals state hydroxychloroquin cure covid pronounc viral share right wing media sound debunk medic academician year later one frontlin joseph ladapo becam surgeon general florida faculti member univers florida colleg medicin continu spread danger misinform covid academ colleagu shame silent | D000086382;D006886;D010820;D003254;D005180 | T047;T121;T090;T109;T057;T097;T067 |
36,228,018 | like like macrophag reduc rsv infect primari bronchial epitheli cell media depend fashion respiratori syncyti virus rsv common childhood infect young infant progress sever bronchiol pneumonia diseas pathogenesi result viral mediat host immun process alveolar macrophag play import part investig role differ type alveolar macrophag rsv infect use vitro co cultur model involv primari tissu deriv human bronchial epitheli cell hbec human blood monocyt deriv like like like macrophag hypothes vitro model would recapitul previous vivo find protect effect macrophag rsv infect found macrophag maintain phenotyp hour co cultur time period bronchial epitheli cell unaffect macrophag media hbec infect rsv decreas like macrophag enhanc like macrophag medium use co cultur also impact outcom infect work demonstr alveolar macrophag phenotyp may differenti role epitheli rsv infect demonstr vitro co cultur model could use investig role macrophag bronchial viral infect | D018357;D018113 | T047;T005 |
36,228,017 | prevent caus cancer texa raceethn major modifi risk factor popul number modifi risk factor design causal relat cancer develop aim estim percentag incid cancer case diagnos person age year texa overal raceethn attribut modifi risk factor | D005006;D009369 | T098;T102;T191 |
36,228,016 | effect differ train frequenc maxim strength perform muscl hypertrophi train individu within subject design sever studi compar resist train rt frequenc may affect larg subject variabl studi aim compar chang lower limb maxim dynam strength rm quadricep femori cross section area csa rt differ week frequenc strength train individu use within subject design twenti four men particip week rt program random divid two condit resist train equal total train volum rtev unequ total train volum rtuv rt protocol use unilater leg press exercis subject lower limb execut one propos frequenc one three timesweek condit effect increas rm csa p howev signific differ observ valu rm p csa p rt frequenc rtev rtuv condit therefor rt perform three time week show similar increas rm csa program perform week regardless train volum equal nevertheless higher rt frequenc allow applic greater ttv ie rtuv higher effect size es valu rm csa respect observ adapt | D053580;D055070 | T046;T061;T042 |
36,228,015 | model impact covid nurs workload qualiti care use process simul higher acuiti level covid patient increas infect prevent control routin increas work demand nurs understand quantifi chang discret event simul des use quantifi effect vari number covid patient assign nurs workload qualiti care model test base usual nurs patient ratio vari number covid posit patient model valid compar outcom step counter field studi test eight nurs des model show nurs workload increas qualiti care deterior nurs assign covid posit patient five covid posit patient demand condit simul nurs don dof person protect equip ppe time shift total hour direct care time reduc hour chang baselin pre pandem case addit nurs walk km increas base pre pandem condit per shift care task averag task queue contribut miss care task increas base pre pandem condit equival hour miss care time care task wait time increas hour comparison baselin pre pandem condit process simul approach may use potenti decis support tool design manag hospit patient care set includ pandem plan scenario | D000086382;D016526 | T047;T081;T067 |
36,228,014 | low rate end stage kidney diseas membran nephropathi singl centr studi decad membran nephropathi commonest caus nephrot syndrom non diabet caucasian adult age year primari membran nephropathi limit kidney clinic manag aim induc remiss either spontan support care immunosuppress describ natur histori condit larg tertiari centr uk | D015433;D007676 | T047 |
36,228,013 | subtract genom analysi comput identif putat immunogen target clinic enterobact cloaca complex enterobact major nosocomi genus enterobacteriacea respons varieti nosocomi infect particular prolong hospit patient intens care unit sinc current antibiot fail treat colistin carbapenem resist enterobacteriacea effort underway find suitabl altern strategi therefor studi conduct revers vaccinolog rv identifi novel putat immunogen target use core proteom differ sequenc type sts clinic enterobact spp moreov introduc structur base approach explor potenti vaccin candid enterobacteriacea famili use conserv domain analysi | D016972;D004756 | T007;T047 |
36,228,012 | effect captur acut long term reflex impair surviv health deepwat fish shortspin thornyhead sebastolobus alaskanus shortspin thornyhead sebastolobus alaskanus benthic deepwat speci famili scorpaenida tag annual alaska sinc low tag return rate may least partial attribut post releas mortal relat captur studi shortspin thornyhead caught bottom hook line longlin gear immedi given reflex test eighteen transport laboratori held day given reflex test given postmortem examin includ histopatholog tissu three given postmortem examin reflex test vessel histolog find could direct link captur hold howev occurr myxozoan protozoa metazoan nematod parasit sometim associ minor inflamm vibrat respons reflex found fish deck fish hold laboratori vestibular ocular respons present fish deck fish laboratori fish abil right success deck fish addit respond slowli laboratori reflex impair may perman may take day week improv reflex respons test tail grab gag operculum flare success deck later laboratori lack reflex may increas risk predat releas may affect behavior relat surviv product | D010473;D014722 | T023;T013 |
36,228,011 | valv angular vein orbiculari oculi depressor supercilii zygomaticus minor aim studi elucid posit relationship cours angular vein facial muscl possibl role latter altern venous valv | D005143;D005152 | T023 |
36,228,010 | nonam depend rag cleavag cpgs explain mechan chromosom transloc associ lymphoid cancer chromosom transloc consid one major caus lymphoid cancer rag complex respons v j recombin also cleav non b dna structur cryptic rsss genom lead chromosom transloc mechan factor regul illegitim function rag result oncogenesi larg unknown upon silico analysi chromosom transloc lymphoid cancer patient find transloc breakpoint possess adjac cryptic nonam rag bind sequenc cpgs proxim proof principl show rag effici bind cryptic nonam present multipl fragil region cleav adjac mismatch generat mimic deamin cpgs chip studi reveal rag inde recogn fragil site chromatin context insid cell final show aid cytidin deaminas play signific role generat mismatch cpgs reconstitut process rag depend generat dna break vitro insid cell thus propos novel mechan generat chromosom transloc rag bind cryptic nonam sequenc direct cleavag adjac mismatch generat due deamin mecpg cytosin | D009369;D014178 | T191;T049 |
36,228,009 | target dose deliveri mycobacterium tuberculosi mice use silicon antifoam agent via aerosol exposur system mycobacterium tuberculosi mtb intracellular pathogen form aggreg clump solid agar plate liquid media deterg tween tyloxapol consid gold standard disrupt clump format mtb cultur presenc deterg howev may generat foam hinder mtb aerosol thus requir addit antifoam agent optim mtb aerosol base procedur aerosol inhal technic challeng particular achiev reproduc inhal target dose studi impact antifoam silicon antifoam agent saf mtb aerosol whole bodi mous aerosol infect investig compar studi use saf liquid suspens contain mycobacterium bovi bcg bovi bcg mtb hrv caus advers effect bacteri viabil incorpor saf mycobacteria inhal procedur reveal aerosol mycobacteri strain maintain control environment condit humid temperatur pressur airflow insid aerosol chamber addit environment factor spray factor affect presenc saf mycobacteri cultur aerosol spray factor signific less aerosol procedur low input dose mycobacteria comparison high dose predict mycobacteri load recov biosampl agi log lower nebul input bacteri load consist mtb bacillari load determin mous lung indic saf affect mycobacteria aerosol aerosol generat process data confirm saf prevent format excess foam aerosol saf negat impact mycobacteri viabil within aerosol droplet mtb droplet within aerosol generat particl well within rang requir reach deposit deep lung tissu saf negat impact achiev target dose mice expos mtb aerosol | D009163;D009169;D014388 | T007;T047 |
36,228,008 | genet variant determin intrafamili variabl sar cov clinic outcom italian famili sever acut respiratori syndrom coronavirus sar cov infect result wide rang outcom character high heterogen symptomatolog suscept diseas perspect covid may consid multifactori diseas featur interact environ virus genet profil host analysi aim investig transmiss dynam sar cov within famili whose member respond differ way infect although exposur common entir group occur avail vaccin goal understand genet background subject influenc viral infect outcom henc mention clinic variabl perform segreg analysi italian famili design custom panel gene involv immun virus entri also shown relat sar cov host respons carri famili segreg analysi global statist analysi former identifi eighteen risk variant co segreg covid posit status six variant possibl protect effect addit sixteen variant show trend associ sever phenotyp togeth common snps detect privat rare variant may also provid insight observ clinic covid heterogen global statist analysi confirm statist signific posit associ sar cov individu respons specif gene variant identifi famili analysi conclus data confirm clinic express covid mark influenc host genet profil mendelian transmiss pattern polygen architectur | D000086382;D014777 | T047;T067 |
36,228,007 | social connected determin mental health scope review public health epidemiolog research establish social connected promot overal health yet recent review find research examin social connected determin mental health goal review evalu recent longitudin research probe effect social connected depress anxieti symptom diagnos general popul scope review perform pubm psychinfo databas januari decemb follow prisma scr guidelin use defin search strategi search yield uniqu studi research pregnant women studi report social support benefit symptom depress remain report minim evid lower level social support predict depress follow research pregnant women studi found low social support increas postpartum depress symptom among studi focus loneli feel lone baselin relat advers outcom follow includ higher risk major depress disord depress symptom sever general anxieti disord lower level physic activ report smaller social network size predict depress symptom disord follow summari recent relev longitudin studi demonstr social connected protect adult general popul depress symptom disord result larg consist across set exposur measur popul support effort improv clinic detect high risk patient includ adult low social support elev loneli | D003865 | T048 |
36,228,006 | communic neglect tropic diseas elimin scope review call action although practic communic often call upon interven involv communiti affect ntds disciplinari framework health communic research larg absent ntd strategi illustr practic conceptu develop within communic field appli context ntd elimin conduct scope review focus two diseas current target elimin lymphat filariasi chaga diseas | D014330;D004605 | T047;T091 |
36,228,005 | develop ferment rice cake contain strawberri show anti inflammatori effect lps stimul macrophag paw edema induc mice strawberri fragaria ananassa one richest sourc contain wide varieti nutrit compound anti inflammatori activ ferment rice cake made strawberri powder well rice powder evalu ferment rice cake contain strawberri powder src signific dose depend inhibit product lps stimul raw cell without cytotox also src effect suppress inflammatori gene express includ ino cox il il tnf addit product pge il il tnf signific reduc furthermor anti inflammatori effect src investig use carrageenan induc paw edema icr mice demonstr pre oral administr src dose mgkg bw signific inhibit paw edema induc carrageenan studi suggest anti inflamm activ strawberri rice cake give potenti increas commerci rice cake rice product | D031985;D012275 | T168;T002 |
36,228,004 | incid factor associ lost follow among peopl live hiv receiv antiretrovir therapi nyarugeng central busi district kigali citi rwanda lost follow ltfup continu threaten sustain antiretrovir therapi art benefit success art program determin incid predictor ltfup among peopl live hiv plhiv art nyarugeng central busi district kigali citi | D019380;D015658 | T121;T047 |
36,228,003 | cnaviz interact webtool user guid segment tumor dna sequenc data copi number aberr cnas genet alter amplifi delet number copi larg genom segment although ubiquit cancer thus critic area current cancer research cna identif dna sequenc data challeng requir partit genom complex segment copi number state may contigu exist segment algorithm address challeng either leverag local inform among neighbor genom region global group genom region affect similar cnas across entir genom howev approach limit overclust case local segment omiss cluster correspond focal cnas case global segment import inaccur segment lead inaccur identif cnas reason pan cancer research studi reli manual procedur qualiti control anomali correct improv copi number segment introduc cnaviz web base tool enabl user simultan perform local global segment thus overcom limit approach use simul data demonstr sever metric cnaviz allow user obtain accur segment relat exist local global segment method moreov analyz six bulk dna sequenc sampl three breast cancer patient valid parallel singl cell dna sequenc data sampl show use cnaviz user abl obtain accur segment improv accuraci downstream copi number call | D009369;D001943 | T191 |
36,228,002 | measur job satisfact midwiv scope review given global shortag midwiv utmost interest improv midwiv job satisfact work environ precis measur tool need identifi predictor job satisfact intervent strategi could increas aim studi collat describ analys instrument use research assess job satisfact midwiv work hospit identifi valid reliabl tool make recommend develop specif instrument midwiferi practic futur midwiferi research | D008880;D009721 | T091;T097 |
36,228,001 | machin learn model train high throughput antibacteri screen increas hit rate drug discoveri screen novel antibacteri compound small molecul librari low success rate appli machin learn ml base virtual screen antibacteri activ evalu predict power experiment valid first binar compound accord growth inhibitori activ hit rate antibiot resist bacterium burkholderia cenocepacia describ molecular featur direct messag pass neural network mpnn use data train ml model achiev receiv oper characterist roc score test set final predict antibacteri activ virtual librari correspond compound food drug administr fda approv list natur product hit rate respect obtain test top rank predict compound growth inhibitori activ b cenocepacia repres least fold increas previous hit rate addit predict antibacteri natur compound inhibit eskap pathogen show predict expand beyond organ specif dataset broad rang bacteria overal develop ml approach use compound priorit screen increas typic hit rate drug discoveri | D055808;D054852 | T062;T170 |
36,227,998 | activ mechan mous cold sens trpm channel cool agonist pip transient receptor potenti melastatin trpm channel primari molecular transduc respons cool sensat elicit menthol cold mammal trpm activ control cool compound togeth membran lipid phosphatidylinositol bisphosph pip knowledg cold sensat therapeut potenti trpm neuroinflammatori diseas pain enhanc understand structur basi cool agonist pip depend trpm activ present cryo electron microscopi structur mous trpm close intermedi open state along ligand pip depend gate pathway result uncov two discret agonist site state depend rearrang gate posit disord order transit gate form elucid molecular basi chemic induc cool sensat mammal | D003080;D050053;D019269;D013697;D015640;D011744 | T116;T109;T123;T040;T070;T043 |
36,227,997 | cellular barcod deciph clonal dynam diseas cellular barcod distinct dna sequenc enabl one track specif cell across time space recent advanc abil detect natur synthet cellular barcod pair singl cell readout cell state mark increas knowledg clonal dynam genealog cell compos varieti tissu organ advanc hold promis redefin view human diseas provid overview cellular barcod approach discuss applic gain new insight diseas mechan provid outlook futur applic discuss unanticip insight gain barcod studi cancer blood cell product describ barcod appli grow array medic field particular increas recognit clonal contribut human diseas | D058893;D060965;D004194 | T047;T191;T043;T062;T087 |
36,227,996 | peptid ligand mediat trade plant growth stress respons decid whether grow divert energi stress respons major physiolog trade plant surviv fluctuat environ show three leucin rich repeat receptor kinas lrr rks act direct ligand perceiv receptor plant peptid contain sulfat tyrosin psi famili peptid mediat switch two oppos pathway contrast known lrr rks activ signal upon ligand bind psi receptor psyr activ express various gene encod stress respons transcript factor upon deplet ligand loss psyr result defect plant toler biotic abiot stress ligand depriv depend activ system potenti enabl plant exert tune regul stress respons tissu proxim metabol dysfunct damag site ligand product impair | D010455;D013312;D014157;D017360;D029681;D000090263 | T046;T032;T116;T002;T121;T123;T040;T039 |
36,227,993 | sentinel p inka cell basement membran form repar nich lung engin ultrasensit report p inka biomark cellular senesc report detect p inka express fibroblast certain senesc characterist appear short birth basement membran adjac epitheli stem cell lung furthermor p inka fibroblast enhanc capac sens tissu inflamm respond increas secretori capac promot epitheli regener addit p inka express requir fibroblast enhanc epitheli regener studi highlight role p inka fibroblast tissu resid sentinel stem cell nich monitor barrier integr rapid respond inflamm promot tissu regener | D016922;D019941;D005347;D008168;D017930;D012038;D004847;D055153 | T022;T023;T025;T116;T028;T042;T123;T043 |
36,227,992 | recycl plastic use hybrid process integr oxid bioconvers provid solut recycl mix plastic | D010969;D059027;D001711;D016958 | T007;T068;T167;T040 |
36,227,990 | viral arsenal sar cov wield versatil protein foil immun system counterattack | D000086382;D000086402;D014764 | T047;T116;T005;T123;T067 |
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