PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,228,473 | novel strategi integr gas phase fraction stagger mass rang lc msms molecular network comprehens metabolit profil gui ling ji rat metabolit detect complex biolog sampl face challeng due interfer endogen substrat inher limit multipl subsequ tandem scan rate instrument new integr approach base gas phase fraction stagger mass rang sgpf liquid chromatographi tandem mass spectrometri lc msms molecular network develop acceler data process target untarget constitu absorb rat oral administr tradit chines medicin tcm prescript gui ling ji glj compar three convent acquisit method sgpf mass fraction could enhanc msms coverag increas msms trigger rate data depend acquisit dda fast dda gas phase fraction mass rang fraction set five optim perform base similar diagnost fragment ion characterist neutral loss behavior dda msms spectrum initi molecular network glj creat help global natur product social molecular network gnps platform furthermor remov endogen interfer node cytoscap softwar adopt produc clean concis molecular network prototyp compound correspond metabolit use strategi total compound includ prototyp constitu metabolit unambigu tentat identifi glj first systemat metabol studi glj vivo elucid potenti pharmacodynam basi glj clinic treatment import work serv practic exampl establish guid rapid identifi tcm metabolit biolog matric | D053719;D004365 | T121;T123;T063 |
36,228,467 | state level variat substanc use treatment admiss among crimin legal refer individu individu involv crimin legal system face uniqu challeng access substanc use disord sud treatment yet state level variat referr treatment remain larg unknown address dispar overdos crisi among individu crimin legal involv import understand variat sud treatment across state | D009293;D062787;D008694;D002047 | T037;T131;T121;T109;T048 |
36,228,459 | lipid composit depend bind apolipoprotein e signal peptid import membran cholesterol protein traffick solubl secretori membran protein contain short stretch signal peptid sp n termin end get cleav reach destin organell howev import sp protein traffick fulli understood lipid composit cellular organell high heterogen prefer sp toward particular lipid composit might play key role unidirect traffick protein order understand prefer apolipoprotein e apo toward endoplasm reticulum er studi interact sp membran vari lipid composit import cholesterol paramount subcellular organell contain differenti amount cholesterol endoplasm reticulum er contain least amount cholesterol util batteri steadi state time resolv fluoresc techniqu understand affin apo signal peptid toward membran vari lipid composit observ apo signal peptid bind tight membran devoid cholesterol bind affin reduc increas concentr membran cholesterol result clear suggest import membran composit unidirect movement apo toward er properti sp util develop organell specif cargo deliveri | D021382;D002784 | T116;T121;T109;T123;T087 |
36,228,453 | inter semispin plane isp block postop analgesia follow cervic spine surgeri prospect random control trial evalu periop analges effect inter semispin plane isp block patient undergo posterior cervic spine surgeri | D009407;D000698 | T061 |
36,228,451 | isotop dilut liquid chromatographi tandem mass spectrometri method serum beta microglobulin quantif beta microglobulin bm common use detect index clinic laboratori current use sensit indic earli detect kidney diseas immunoassay common use method bm detect clinic practic liquid chromatographi tandem mass spectrometri lc msms chang face laboratori test provid high throughput analysi better specif detect method use antibodi isotop dilut lc msms id lc msms method develop serum bm quantif bm denatur reduct alkyl cystein residu trypsin ad digest bm purifi solid phase extract column sampl inject high perform lc msms measur signatur peptid vnhvtlsqpk select surrog bm stabl isotop label peptid vnhvt c n lsqp use intern standard quantifi bm base calibr curv method linear rang serum bm calibr curv mgl limit quantif mgl limit detect mgl differ concentr serum bm precis coeffici variat cv rang accuraci relat error within nomin valu applic reliabl method verifi measur bm erm dakifcc serum sampl valid lc msms method success appli clinic studi involv quantif serum bm patient acut renal insuffici healthi individu deme analysi show id lc msms immunoassay good agreement lc msms method develop sensit reliabl absolut quantif serum bm | D053719;D001613 | T116;T123;T063 |
36,228,449 | adher life simpl associ better carotid properti cardiovascular health score emerg simpl way assess risk suffer cardiovascular diseas american heart associ life simpl constitut modifi lifestyl factor reduc cardiovascular risk associ carotid properti yet inconclus aim studi determin associ adher life simpl carotid properti middl age elder finn | D001786;D002318 | T047;T109 |
36,228,442 | impact frailti day death stroke myocardi infarct sever carotid stenosi endarterectomi versus stent carotid endarterectomi cea carotid arteri stent cas use stroke prevent patient carotid stenosi remain unclear surgic approach produc best outcom elder frail patient investig impact age frailti day combin outcom death stroke myocardi infarct mi patient receiv cea cas sever symptomat carotid stenosi | D016893;D000073496;D016894;D020521;D009203 | T047;T046;T061;T020;T184;T033 |
36,228,441 | applic modifi lifeso radiograph stage system manag outcom craniocerv tuberculosi describ manag algorithm cervicovertebr junction cvj tb base upon diseas sever neurolog status present | D001268;D014399;D013123 | T061;T047;T030 |
36,228,430 | circul mir potenti regul immun respons differ vaccin chicken vaccin one effect mean prevent viral infecti diseas poultri howev function circul mirna immun respons remain unknown studi mir key factor regul immun function select studi express potenti function mechan day old chicken immun respons three vaccin avian influenza virus inactiv vaccin newcastl diseas virus attenu vaccin infecti bursal diseas virus attenu vaccin respect experi aim explor relationship express level serum circul mir immun respons result show express level serum circul mir signific differ three immun respons similar sever time point post inocul day post inocul dpi dpi dpi possibl common key time point three immun respons moreov spleen dpi bursa fabricius cecal tonsil dpi liver dpi possibl key tissu associ differenti express level serum circul mir bioinformat analysi show sever key target gene kras rapb rpska mir possibl play key role immun function regul mapk mtor signal pathway studi lay foundat studi function applic circul mir chicken immun respons | D011201;D007243;D035683;D014765;D018175 | T047;T121;T123;T114;T129;T005 |
36,228,429 | effect myostatin gene mutat erythrocyt osmot fragil hematolog paramet fatti acid composit serum erythrocyt membran piglet fatti acid composit serum erythrocyt membran erythrocyt osmot fragil hematolog paramet estim object determin effect gene mutat one week old mstn homozyg mutant ko mstn heterozyg mutant mstn wild type wt mstn piglet n erythrocyt osmot fragil complet blood count cbc fatti acid composit serum erythrocyt membran determin flow cytometr analysi autom hematolog analyz system liquid chromatographi respect mean median corpuscular fragil mcf lower p ko mstn wt piglet ko piglet decreas p white blood cell wbc count lymphocyt lym count platelet plt count mean corpuscular volum mcv mean corpuscular hemoglobin mch red cell distribut width standard deviat rdw sd red cell distribut width coeffici volum rdw cv plateletcrit pct mean platelet volum mpv platelet distribut width pdw platelet larg cell ratio p lcr increas red blood cell rbc count compar mstn wt piglet ratio unsatur fatti acid ufa satur fatti acid sfa concentr serum erythrocyt membran mstn ko piglet fold fold higher compar wt piglet p respect conclus mstn ko piglet decreas erythrocyt osmot fragil alter hematolog profil fatti acid composit serum erythrocyt membran characterist phenotyp | D055435;D004910 | T026;T123;T116 |
36,228,423 | distract chronic pain impact chronic pain drive behaviour hazard percept road safeti research studi examin drive behaviour chronic pain cohort aim studi investig drive behaviour among driver experienc chronic pain compar individu chronic pain age gender match healthi control particip complet anonym onlin survey includ particip demograph transport characterist self report drive behaviour pain characterist ii respons time hazard percept test verbal respons hazard predict test driver iii drive diari particip record drive two week result show particip chronic pain signific wors control hazard percept predict test score self report attent relat error drive error drive violat involuntari distract driver chronic pain report signific drive laps effect becam non signific variabl confound chronic pain fatigu adjust also found particip report particular high level chronic pain perform wors hazard predict test compar control group effect could account variabl associ chronic pain addit particip chronic pain report signific higher drive workload mental demand physic demand effort frustrat compar control find studi provid new insight drive behaviour individu chronic pain recommend futur research term drive assess self regul strategi provid | D059350;D001334 | T056;T047;T184 |
36,228,416 | health profession view medic teleconsult uptak brazilian unifi health system descript use nasss framework covid pandem acceler effort deploy regul medic teleconsult brazil studi brazilian unifi public health system sus experi implement teleconsult help inform sustain studi identifi chang requir integr special teleconsult local workflow sus | D019114;D000086382 | T047;T060;T067 |
36,228,415 | ai explain affect physician intent use ai artifici intellig ai increas develop support clinic decis better health servic qualiti adopt ai hospit popular expect possibl reason unclear ai explain xai affect physician consider adopt model | D001185;D010820 | T090;T097;T066;T073 |
36,228,407 | annual profil impact simul oil spill northeast arctic cod haddock fisheri simul combin natur pollut induc surviv earli life stage nea cod haddock impact adult popul respons time major oil spill singl year simul reveal dynam ocean process control oil transport fate frequenc interact oil drift fish egg larva mediat magnitud popul loss due oil spill largest impact fish earli life stage occur spill initi feb mar concomit initi rise marin product earliest phase spawn season reproduct health adult fish popul maintain scenario studi demonstr applic simul system provid manag inform plan develop activ protect fisheri resourc potenti impact | D059392;D048388;D004785 | T069;T131;T168;T013 |
36,228,393 | miniatur electrochem devic base nitrogen carbon codop bimet real time monitor acetaminophen dopamin urin situ real time detect drug metabolit biomolecul hospit patient urin help doctor monitor physiolog indic regul use drug dose work nitrogen dope carbon support bimet prepar screen print electrod spes appli real time monitor acetaminophen ac dopamin da urin via one step pyrolysi core shell cubic precursor cu co cn co co cn cuco coco nitrogen dope carbon support bimet cuco nc form bimet composit present twice higher catalyt activ counterpart singl metal addit nanocomposit exhibit strong conduct pyrolysi promot electron transport effici indic imped measur accord cuco nc base sensor offer excel sensit detect limit nm nm detect rang detect ac da respect final combin miniatur electrochem devic sensor appli situ real time monitor ac da urinari bag h compar techniqu high perform liquid chromatographi uv spectrophotometri fluoresc spectromet biosensor demonstr advantag real time monitor easi oper excel portabl howev multi compon detect self calibr function need develop method pave way continu monitor drug metabolit biomolecul hospit patient | D004298;D015374 | T059;T121;T075;T109;T123 |
36,228,392 | simultan ultrasensit adp atp quantif base crisprcasa integr zif ag aus fe nanocomposit adpatp ratio sensit indic chang cellular energi status import regul cell signal activ ultrasensit quantif adp atp concentr singl system great demand bioanalysi earli diseas diagnosi henc target regul lumin nanoplatform base cluster regular interspac short palindrom repeat crispr casa integr zeolit imidazol framework zif ag aus fe nanocomposit establish simultan detect adp atp simultan ultrasensit quantif nanoplatform dsdna zif ag aus fe compos adp sensit modul base aptam activ crisprcasa atp respons modul base atp trigger zif decomposit quencher load releas bind signal process differ nucleotid independ interfer two modul util high specif bind strong signal amplif method limit detect low nm obtain within min adp atp respect moreov propos biosensor exhibit high accuraci specif excel recoveri serum sampl bacteri biofilm therefor dsdna zif ag aus fe base nanoplatform provid promis method ultrasensit dual mode quantif adp atp system possess great potenti bioanalysi earli diseas diagnosi | D015374;D017641;D053761 | T059;T075;T073;T197 |
36,228,387 | congenit cholesteatoma ident twin congenit cholesteatoma ident twin describ otolaryngolog literatur thus far report describ case monozygot twin histori recurr acut otiti media bilater middl ear effus without tympan membran perfor upon myringotomi pressur equal tube insert found right side cholesteatoma near ident locat pattern progress context previous case seri demonstr famili cluster report possibl genet associ condit author present import addit current understand congenit cholesteatoma disord | D002781;D018424;D010034;D018058 | T047;T037 |
36,228,364 | sourc free domain adapt imag segment domain adapt da drawn high interest capac adapt model train label sourc data perform well unlabel weak label target data differ domain common da techniqu requir concurr access input imag sourc target domain howev practic privaci concern often imped avail sourc imag adapt phase frequent da scenario medic imag instanc sourc target imag could come differ clinic site introduc sourc free domain adapt imag segment formul base minim label free entropi loss defin target domain data guid weak label target sampl domain invari prior segment region mani prior deriv anatom inform class ratio prior estim anatom knowledg integr form kullback leibler kl diverg overal loss function furthermor motiv overal loss interest link maxim mutual inform target imag label predict show effect prior awar entropi minim varieti domain adapt scenario differ modal applic includ spine prostat cardiac segment method yield compar result sever state art adapt techniqu despit access much less inform sourc imag entir absent adapt phase straightforward adapt strategi use one network contrari popular adversari techniqu applic sourc free da set framework readili use breadth segment problem code public avail https githubcommathild bsfda | D011467;D013131 | T023 |
36,228,361 | long term exposur microplast induc intestin function dysbiosi rare minnow gobiocypri rarus microplast ubiquit natur environ especi water potenti impact also key issu concern studi use gl polystyren ps mps particl analyz effect exposur day rare minnow gobiocypri rarus result indic ps mps induc structur alter intestin tissu includ epitheli damag villi damag inflammatori cell infiltr chang sever exposur day polystyren microplast also signific increas activ catalas cat increas superoxid dismutas sod increas content malondialdehyd mda increas glutathion gsh increas result show character gut microbi communiti rare minnow also indic microbi divers composit alter gut fish expos ps mps control group proteobacteria actinobacteriota fusobacteriota bacteriadota four domin bacteri phyla intestin rare minnow exposur microplast gut microbiota proport proteobacteria increas exposur time actinobacteria decreas signific differ day addit metabolom analysi suggest exposur ps mps induc alter metabol profil rare minnow differenti metabolit involv energi metabol inflammatori respons secret oxid stress nucleotid metabolom conclus find suggest long term exposur microplast could induc intestin inflamm oxid stress microbiota dysbiosi metabol disord rare minnow alter sever exacerb prolong exposur studi extend cognit toxic polystyren enrich theoret data explor toxicolog mechan microplast | D003530;D014874 | T131;T013 |
36,228,360 | masculin steroid milieu caus fluoren bisphenol disrupt sex typic courtship behavior femal zebrafish danio rerio vertebr behavior congenit sex differ male femal high depend steroid signal hormon milieu presenc endocrin disrupt chemic edc environ general play similar role sex hormon interfer aquat organ popul stabil ignor worth studi fluoren bisphenol bhpf clarifi endocrin disruptor organ sever studi mechan perturb courtship behavior femal zebrafish clear propos autom multi zebrafish track method quantifi courtship process report zebrafish femal expos bhpf recept male rather court femal lose normal ovarian function alter sex steroid milieu result show bhpf damag estradiol synthesi regul sox cypaa link apoptosi ovari develop femal fecund regul express estrogen signal estrogen receptor esrb caus induct masculin femal courtship behavior sexual prefer zebrafish femal bhpf treatment process might mediat inhibit transcript neuropeptid b npb brain studi reveal estrogen signal pathway may play import role classic courtship behavior sexual prefer zebrafish studi provid evid anti estrogen chemic exposur caus advers effect regul brain gonad estrogen axi aquat organ concern highlight import control environment contamin | D014874;D052244 | T131;T039 |
36,228,359 | prenat pm exposur contribut neuron tau lesion male offspr mice mitochondri dysfunct mediat insulin resist epidemiolog evid link prenat exposur fine particul matter pm pollut neurolog diseas offspr howev biolog process toxicolog mechan remain unclear tau protein neuron microtubul associ protein express fetal brain play critic role mediat neuron develop aberr express tau associ advers neurodevelopment outcom studi whether prenat exposur pm pollut induc tau lesion mice offspr elucid under pathogen mechan expos pregnant mice pm mgkg bw oropharyng aspir everi day result indic prenat pm exposur induc hyperphosphoryl tau cortex postnat male offspr accompani insulin resist ir pikakt signal pathway import found prenat pm exposur induc mitochondri dysfunct disrupt mitochondri ultrastructur decreas express rate limit enzym cs idh fh kreb cycl subunit mitochondri complex iv v co co atp atp postnat neurodevelop find suggest prenat pm exposur could induc tauopathi like chang male offspr mitochondri dysfunct induc insulin resist might play import role | D007333;D011297 | T046;T037 |
36,228,358 | effect multi wall carbon nanotub soil earthworm growth reproduct enzymat activ metabolom increas product environment releas multi wall carbon nanotub mwcnts increas soil exposur potenti risk earthworm howev mwcnt toxic earthworm remain unclear studi identifi negat effect other neglig effect studi determin whether exposur mwcnts negat affect earthworm elucid possibl mechan toxic earthworm expos subleth soil concentr mwcnts mgkg day earthworm growth reproduct activ cytochrom p cyp isoform c antioxid enzym superoxid dismutas sod catalas cat glutathion transferas gst metabolom determin effect mwcnts earthworm depend exposur concentr exposur mwcnts signific affect growth reproduct individu earthworm exposur mgkg mwcnts signific increas activ cypc cypa sod cat gst clear reduc level l aspart l asparagin glutamin exposur mgkg mwcnts toxic effect earthworm observ signific inhibit activ cyp isoenzym sod signific reduct l aspart l asparagin glutamin tryptophan simultan accumul citrat isocitr fumar oxoglutar pyruv galactos carbamoyl phosphat formyl anthranil hypoxanthin xanthin result suggest toxic mwcnts earthworm associ reduc detoxif capac excess oxid stress disturb multipl metabol pathway includ amino acid metabol tricarboxyl acid cycl pyruv metabol galactos metabol purin metabol studi provid new insight better understand predict toxic mwcnts soil | D009835;D037742;D012989 | T104;T131;T073;T204 |
36,228,357 | associ short term exposur pm constitu hospit admiss cardiovascular diseas among major chines citi previous studi show differ risk effect exposur fine particul matter pm mass cardiovascular diseas cvd global like due differ constitu pm studi aim investig associ short term exposur pm constitu hospit admiss cvd daili count citi specif hospit admiss cvd citi china extract nation urban employe basic medic insur databas beij municip commiss health famili plan inform center databas direct measur pm constitu includ ion polycycl aromat hydrocarbon collect chines environment public health track system use time stratifi case crossov design estim associ pm constitu hospit admiss cvd concentr ion account major detect constitu excess risk er averag ion concentr cvd highest ci nh whose major sourc residenti agricultur emiss follow general vehicl often fossil fuel burn respect associ ion general consist ischem heart diseas ihd ischem stroke eg nh associ ihd ischem stroke polycycl aromat hydrocarbon pah main coal vehicl relat oil combust constitu associ ischem stroke ihd er ischem stroke highest indeno cd pyren thus term subtyp cvd risk hospit admiss vari exposur differ pm constitu expos nh highest risk ihd ischem stroke wherea pah predomin associ ischem stroke | D000397;D002318;D000393;D011084;D000083242 | T047;T131;T069;T109;T080 |
36,228,356 | ozon caus depress like respons pikaktgsk pathway modul synapt plastic young rat ozon pollut associ sever advers effect includ memori impair intellectu retard emot disturb howev potenti mechan remain uncertain present studi aim investig whether ozon regul synapt plastic pikaktgsk signal pathway induc neurobehavior modif among young rat vivo newborn rat use construct anim model earli postnat treatment vitro studi measur effect differ concentr serum treat rat viabil pc cell investig modif synapt plastic pikaktgsk signal pathway hippocampus pc cell treat result reveal signific depress like behavior increas hippocamp histopatholog damag young rat treat compar control group express level synapt relat protein includ drebrin psd synaptophysin pikr p akt p gsk decreas treat group vitro assay signific reduct drebrin psd synaptophysin pikr p akt p gsk found pc cell serum treat p specif pik activ administ express level drebrin psd synaptophysin pikr p akt p gsk p group signific elev vivo vitro compar group addit mirna modul pikr screen bioinformat websit studi found aberr express mir p hippocampus serum treat group inhibit mir p express effect revers reduct drebrin psd synaptophysin pikr p akt p gsk pc cell induc treatment altogeth studi indic restrain express pikaktgsk signal pathway impair synapt plastic result depress like behavior young rat moreov mir p play import role procedur regul pikr | D010126;D035683 | T103;T123;T114 |
36,228,355 | decabromodiphenyl ethan induc male reproduct toxic glycolipid metabol imbal meiotic failur decabromodiphenyl ethan dbdpe typic flame retard found various electr textil item dbdpe abund avail surround environ wild anim base persist bioaccumul dbdpe shown caus apoptosi rat spermatogen cell result reproduct toxic howev toxic dbdpe male reproduct system potenti mechan still unclear studi evalu effect dbdpe reproduct system male sd rat demonstr potenti mechan reproduct toxic dbdpe mgkgday administ via gavag male sd rat day dbdpe caus histopatholog chang testi reduc sperm quantiti motil rais malform rate rat accord find furthermor caus dna damag rat testicular cell inhibit express spermatogenesi oogenesi specif helix loop helix transcript factor sohlh piwi like rna mediat gene silenc mili cyclin depend kinas cdk cyclina result meiotic failur well express synaptonem complex protein sycp sycp lead chromosom associ disord meiosi spermatocyt cycl arrest moreov dbdpe induc glycolipid metabol disord activ mitochondria mediat apoptosi pathway test sd rat quantiti qualiti sperm might declin due factor find offer evid harm impact dbdpe male reproduct system | D012661;D005411 | T120;T031 |
36,228,354 | enhanc cadmium phytoremedi capac poplar associ increas biomass cd accumul nitrogen deposit condit nitrogen n deposit play signific role soil cadmium cd phytoremedi poplar consid remedi contamin soil enorm biomass strong cd resist reveal under physiolog root phenotyp mechan n deposit affect cd phytoextract poplar assess root phenotyp characterist cd absorpt transloc chlorophyl fluoresc perform antioxid enzym activ clone populus deltoid p nigra combin greenhous cd n experi result show cd signific chang root phenotyp reduc root length tip number diamet cd also caus peroxid lipid damag photosystem ii psii reaction centr reduc photosynthet capac result decreas biomass accumul poplar n kg nha yr n kg nha yr treatment promot net photosynthet rate poplar increas activ antioxid enzym prolin content repair psii reaction centr thus increas biomass accumul poplar expos cd stress simultan n n treatment might increas cd uptak soil upregul total root length root tip fine root length cd main accumul root stem leav n kg nha yr treatment obvious effect paramet compar singl cd treatment consequ studi suggest adequ n improv biomass cd accumul enhanc phytoremedi capac poplar cd might relat improv leaf physiolog defenc chang root phenotyp characterist | D032107;D012989 | T131;T002 |
36,228,353 | assess biotox lanthanid la ce gd ho zebrafish danio rerio differ water environ expand applic lanthanid ln various aspect rais concern biosafeti slight chang chemic composit environment media signific affect biolog effect poor water solubl ln howev knowledg effect environment factor ln toxic remain limit effect ph hco ca mg na k cl bioefficaci biotox ln la ce gd ho compar studi use zebrafish danio rerio test organ standard water toxic ln zebrafish signific correl ph hco ca mg level medium level cl na k begin test four ln complex hco medium form precipit decreas ph hco concentr promot convers granular ln solubl state thus enhanc bioavail biotox bioaccumul ph mmoll hco ln precipit found four ln show consist trend h lc zebrafish data indic differ toxic four ln standard water may due differ effect state individu element rather differ toxic element overal biolog toxic assess ln regard group element addit pattern toxic differ biolog toxic mechan reveal effect ph carbon consid | D028581;D014874 | T131;T196 |
36,228,352 | cellular transport uranium cytotox effect cho k cell uranium radioact heavi metal signific public health concern howev associ under toxicolog mechan remain larg unknown work uptak efflux process uranium cho k cell studi cytotox effect explor found uptak efflux process took place rapid half intern uranium expel within h uranium exposur caus decreas cell viabil adhes abil dose depend manner block cell cycl g stage addit gene express analysi reveal relat chang transcript metabol relat gene studi reveal cytotox uranium could allevi expos cell lower temperatur addit amantadin hcl endocytosi inhibitor interest uranium exposur needl like precipit observ intracellular extracellular region find collect suggest cellular transport uranium rapid process disturb cell metabol induc cytotox impact could reduc slow endocyt process | D014501 | T196 |
36,228,351 | novel high diverg canin distemp virus lineag caus distemp ferret australia canin distemp virus cdv caus high contagi system infect array anim speci studi report outbreak distemp ferret two research facil australia caus novel lineag cdv cdv strain caus main mild symptom ferret histopatholog result present typic profil distemp patholog multi system virus replic develop discriminatori pcr pair full genom sequenc reveal outbreak caus novel lineag cdv novel cdv lineag high diverg less similar across h gene describ lineag includ vaccin strain diverg approxim year ago enhanc surveil determin preval cdv ferret dog risk speci critic better understand presenc divers cdv australia current | D004217;D004216 | T047;T005 |
36,228,338 | longitudin associ pain substanc use disord treatment outcom pain common report among treatment substanc use disord sud associ poorer sud treatment outcom current studi examin trajectori pain cours sud treatment associ substanc use outcom | D019966;D009293 | T048;T033 |
36,228,328 | advanc bulki deliveri system use novel techniqu percutan pulmonari valv implant percutan pulmonari valv implant challeng advanc deliveri system load stent valv right ventricular outflow tract extra stiff wire provid enough support stabl posit prevent displac guid wire stent valv deliveri case report use snare trap extra stiff wire larg sheath support snare thus extra stiff wire pull distal end provid strong support advanc deliveri system month follow patient good condit excel valv function name novel effici techniqu parallel anchor sheath snare techniqu report highlight novel deliveri strategi patient tortuous right ventricular outflow tract percutan pulmonari valv implant | D006350;D019918;D011664;D011665;D014694 | T023;T046;T047;T061;T074 |
36,228,327 | improv right ventricular systol function cardiac resynchron therapi patient heart failur sinc introduct cardiac resynchron therapi crt improv left ventricular function effect crt right ventricl patient heart failur well describ | D058406;D009202;D006333 | T061;T047;T046 |
36,228,322 | carboxyl acid direct lacton unactiv primari c h bond catalyz mn complex applic stereoselect natur product diversif reaction enabl select function strong aliphat c h bond open new synthet path rapid increas molecular complex expand chemic space particular valuabl reaction site select direct toward specif c h bond catalyst control herein describ catalyt site stereoselect lacton unactiv primari c h bond carboxyl acid substrat system reli chiral mn catalyst activ aqueous hydrogen peroxid promot intramolecular lacton mild condit via carboxyl bind metal center system exhibit high site select enabl oxid unactiv primari c h bond even presenc intrins weaker priori reactiv secondari tertiari one carbon substrat bear nonequival c h bond factor govern site select uncov remark manipul absolut chiral catalyst lacton methyl group gem dimethyl structur unit rigid cyclic bicycl carboxyl acid achiev unpreced level diastereoselect control success exploit late stage lacton natur product camphor camphan ketopin isoketopin acid dft analysi point toward rebound type mechan initi intramolecular hat primari c h bond bound substrat high reactiv mn iv oxyl intermedi deliv carbon radic rapid lacton carboxyl transfer intramolecular kinet deuterium isotop effect label experi provid strong support mechanist pictur | D002264;D001688 | T121;T109;T123 |
36,228,320 | enantioselect total synthesi dysiherbol c herein report enantioselect total synthesi dysiherbol c uniqu group pentacycl quinonehydroquinon sesquiterpen featur photo induc quinon alken cycloaddit tandem anion rearrangementcyclopropan fragment key element base total synthesi origin propos structur dysiherbol c revis detail comput studi carri gain deep insight unpreced anion rearrang reveal transform albeit symmetri forbidden process proceed concert manner owe releas high ring strain energi evolut local aromat transit state take present work offer mechanist interest synthet use approach access dysiherbol relat congen | D006873;D012717 | T121;T109 |
36,228,313 | deeper understand solvent base ambient ionize mass spectrometri molecular profil primarili dictat extract mechan solvent base ambient ionize mass spectrometri ms techniqu provid power approach direct chemic analysi molecular profil biolog tissu molecular profil tissu wide use diseas diagnosi littl understood interplay among solvent properti matrix effect ion suppress influenc detect biolog molecul perform systemat investig extract process lipid use ambient ionize droplet microsampl platform investig physicochem properti solvent system extract time influenc molecular extract detect direct molecular profil quantit liquid chromatographi mass spectrometri lc ms discret solvent droplet surfac sampl investig provid insight extract ionize mechan result studi suggest intermolecular interact hydrogen bond play major role extract detect lipid use solvent base ambient ionize techniqu addit extract time observ impact molecular profil obtain suggest optim paramet perform favor detect specif analyt | D008055;D021241 | T059;T109 |
36,228,310 | optimum dose oral folic acid supplement transfus depend thalassemia random control trial compar effect differ dose oral folic acid fa supplement mgday vs mgday vs mgweek proport children folat excess serum folat ngml plasma homocystein hcys excess moll transfus depend thalassemia tdt | D005492;D013789 | T121;T047;T109;T127 |
36,228,309 | impact interpregn interv perinat neonat outcom multiethn pakistani popul short birth interv sbis long birth interv lbis shown serious implic health mother children studi aim investig determin reproduct outcom sbi lbi multiethn pakistani popul | D001721;D066087 | T079;T033 |
36,228,308 | enterobact agglomeran uncommon caus communiti acquir bacteri infect neonat enterobact agglomeran former term erwina herbicola call pantonea agglomeran ubiquit gram negat bacterium rare caus mild opportunist infect human sourc infect myriad caus local system diseas across system bodi infect often fulmin fatal neonat aim report anoth facet infect seen centr neonat recruit studi bacteria isol blood eight e agglomeran sepsi infect acquir communiti though sourc could determin clinic featur non specif run mild cours toxic granul elev immatur polymorph count procalcitonin level found neonat isol sensit test antibiot show sensit gentamicin ciprofloxacin surviv rate excel | D001424;D017714;D020636 | T007;T047 |
36,228,307 | molecular diagnost complic pneumonia post vaccin era etiolog diagnosi communiti acquir pneumonia cap still challeng compar convent cultur method real time polymeras chain reaction rt pcr identif streptococcus pneumonia sever pediatr cap | D017714;D010996;D011014 | T050;T047 |
36,228,305 | farnesol modul rhodotorula mucilaginosa biofilm plankton form biofilm import virul human pathogen fungi molecul found play key role growth regul fungal biofilm farnesol one molecul well describ microorgan still scarc known rhodotorula spp studi aim evalu influenc farnesol biofilm r mucilaginosa initi screen mm mm farnesol evalu plankton form concentr compound chosen evalu effect biofilm format preform biofilm hour impact farnesol evalu coloni form unit cfu count determin metabol activ quantif total biomass presenc mm farnesol abl decreas cfu number hour biofilm format although affect preform biofilm thus result show farnesol exert modul activ biofilm format r mucilaginosa compound reduc metabol activ total biomass biofilm | D005204;D012248 | T121;T109;T004 |
36,228,304 | antimycobacteri anti inflammatori activ fraction substanc erythrina verna vell focus dual sever tb treatment approach tuberculosi remain major health problem worldwid drug resist hypervirul mycobacterium tuberculosi mtb strain lead hyperinflammatori respons necrot patholog hyper reactiv individu requir adjunct treatment plant deriv substanc investig tb treatment among flavonoid stand evalu anti mtb anti inflammatori cytotox activ fraction substanc isol erythrina verna bioassay guid fraction seven fraction obtain dichloromethan e verna extract inhibit product ic gml none poor cytotox effect fraction notabl reduc tnf product fraction suppress mycobacterium growth mic gml fraction potent due dual biolog activ erythratidinon alpinumisoflavon inhibit growth mtb hrv hypervirul strain bacteri cultur mic gml erythratidinon stand reduc intracellular growth mtb hrv gml alpinumisoflavon erythratidinon capabl inhibit tnf product besid show signific inhibitori effect mycobacterium tuberculosi strain low toxic macrophag substanc promis studi focus anti tb dual treatment approach | D004895;D009169 | T007;T002 |
36,228,303 | year diatom studi brazil knowledg gap perspect actual status progress main aspect diatom studi brazil remain unknown paper describ survey publish studi address materi brazilian origin non marin aquat environ object summar categor diatom research topic describ relat studi evolv develop time well respect journal identifi studi region environ indic main institut work address diatom research relat interact conduct systemat review select studi sinc earli studi approach diatom florist exclus frequent even though ecolog studi increas sinc howev concentr southern southeastern last decad brazilian region becam set extens sampl thus reflect interact author institut collect site howev actual biodivers scenario diatom brazil still seem underestim may influenc conserv measur final indic suggest aim fill sampl gap presentedhighlight studi | D017377 | T204 |
36,228,302 | wintertim tale lizard liolaemus lineomaculatus endur temper cold climat patagonia argentina temper polar montan environ ectotherm must find way endur throughout coldest month year lizard search microsit temperatur remain warm alter biochem balanc toler freez avoid supercool evalu cold hardi potenti winter refug two popul liolaemus lineomaculatus temper site cold site analys role possibl cryoprotect compar group cool lizard control group lizard expos cold popul studi freez toler biochem analysi show evid metabolit signific chang concentr exposur cold howev speci remain sever hour supercool point scp suggest supercool analysi potenti winter refug show lizard use potenti refug would spend almost time temperatur close scp furthermor lizard cold site abl surviv c temperatur lower scp lizard temper site liolaemus lineomaculatus develop physiolog mechan help surviv temperatur drop sharpli even lizard suitabl shelter | D008116 | T014 |
36,228,301 | develop anthocyanin marker gene map genom analysi genet divers studi ipomoea speci anthocyanin pigment respons wide rang colour plant blue red purpl play essenti biolog role well gene evolutionarili conserv purpl sweet potato anthocyanin predomin colour even though present orang root mask carotenoid sever studi focus molecular aspect anthocyanin gene main wild ipomoea speci although structur segreg analysi gene sweet potato hexaploid speci still unknown base exon prime intron cross epic approach fourteen pair primer design five structur anthocyanin gene candid strategi exploit intron length polymorph ilp candid gene cg result success marker give scorabl reproduc allel result allow defin partial structur sequenc intron exon select cg determin pattern sequenc variat evalu marker dosag allel segreg ipomoea batata l lam map popul identifi sever allel linkag analysi studi valid util ilp cg marker genet divers conserv applic success amplif gradient across wild ipomoea speci valid transfer | D027741;D027723 | T168;T002 |
36,228,300 | wood inhabit macrofungi hymenochaetal polyporal basidiomycota amazon forest relationship abiot factor substrat colon hymenochaetal polyporal import macrofungi mainten tropic forest sinc act direct nutrient cycl wood decomposit amazon largest tropic forest world knowledg agaricomycet still insipi sinc mani area yet inventori new record appear new studi increas ecolog knowledg hymenochaetal polyporal brazilian amazon region collect conduct western par brazil relat fungi substrat colon environment variabl speci identifi greater macrofungi rich associ raini season fungi show prefer dead wood small diamet class cm stage decomposit still rigid intermedi abund rich hymenochaetal polyporal influenc air humid assemblag composit influenc temperatur air humid rainfal result indic rich divers western par region speci associ environment condit may threaten increas pressur human activ brazilian amazon | D001487;D020072 | T004 |
36,228,299 | associ forest resourc water avail tempor analysi serra azul stream sub basin veget expect influenc process water cycl structur effect key ecosystem function watersh howev tropic forest submit anthropogen pressur result great disturb function ecosystem servic thus present studi use landscap scale analysi explor associ land use chang water avail serra azul stream watersh land use transit year investig set robust landscap metric analyz across studi region includ water bodi perman preserv area correl analysi water volum serra azul reservoir landscap metric also perform verifi associ forest resourc water avail result show region submit sever impact associ loss forest area result landscap transform throughout region forest fragment associ loss connect sever limit water resourc avail besid reduc basin environment resili role differ manag instrument water resourc protect also discuss emphas need particip stakehold creation process environment protect instrument | D017753;D045483 | T082;T070 |
36,228,298 | mesenchym stem cell amelior effect coliti model via nrfho pathway evalu amelior effect mesenchym stem cell mscs acet acid coliti model via nrfho pathway rat | D003092;D059630 | T047;T025 |
36,228,297 | tranexam acid effect postop bleed outcom laparoscop sleev gastrectomi control studi demonstr control studi whether use tranexam acid bariatr surgeri effect bleed control | D000933;D010535;D014148;D054556 | T047;T061;T060;T121;T109 |
36,228,296 | combin cellular thermometri reveal salmonella typhimurium warm macrophag induc pyroptosi like phenotyp attenu salmonella typhimurium vnp enrich tumor known antitumor effect recruit macrophag littl known howev whether vnp lead specif chang macrophag eg cell temperatur use real time wireless multicel thermometri system report first time vnp increas macrophag temperatur c nigericin recogn induc pyroptosi found induc macrophag warm moreov sipd vnp strain fail induc macrophag pyroptosi simultan fail warm macrophag gsdmd macrophag unabl achiev pyroptosi longer warm follow vnp induct result suggest occurr macrophag pyroptosi key vnp mediat cell warm aid singl cell thermometri system confirm cell warm occur pyroptosi like macrophag cellular warm detect induct pyroptosi macrophag loss mitochondri biolog function suggest critic role mitochondria warm moreov found vnp caus local tumor temperatur increas local tumor warm induc vnp signific reduc macrophag clearanc notabl temperatur increas contribut type polar find expand knowledg cellular biolog chang induc strain macrophag well biochem phenomena accompani pyroptosi provid refer studi biochem signal transduc biotherm signal combin cell level temperatur detector | D012486;D062125 | T007;T060 |
36,228,294 | strategi thirst manag postop adult patient scope review map strategi manag thirst postop adult patient | D007053;D013894 | T039;T197 |
36,228,293 | percept men perpetr violenc patern learn percept men judici process due spousal violenc patern | D005219;D010334 | T054;T060 |
36,228,292 | construct valid serial album companion patient stroke construct valid serial album use hospit discharg plan patient stroke | D033062;D020521 | T098;T054;T047 |
36,228,291 | violenc nurs worker repercuss patient access safeti analyz repercuss violenc nurs profession access safeti patient famili health strategi | D058445;D009740;D064450 | T054;T097;T048 |
36,228,290 | nurs workload associ neonat mortal risk cross section studi analyz associ nurs workload neonat mortal risk newborn admit neonat intens care unit | D007363;D016526 | T093;T081;T073 |
36,228,289 | anesthesia seizur like behavior effect two amazonian plant acmella oleracea piper alatabaccum zebrafish danio rerio current avail fish anesthet produc import side effect includ respiratori arrest distress easi implement altern low toxic need ensur fish health well help artisan fisheri fish seller handl transport fish nativ plant seem best altern aim implement anesthet protocol use crude ethanol extract flower leav two amazonian plant acmella oleracea piper alatabaccum first test extract anesthesia use zebrafish model even though treatment anim appar enter deep anesthesia mani present aberr behavior even die thus perform new experi test extract effect seizur like behavior fish leaf extract oleracea potenti effect fish anesthesia flower extract plant leaf extract p alatabaccum induc seizur like behavior anim conclus besid bring possibl new anesthet protocol fish work draw attent neurotox effect anesthet solut may caus sinc sever studi defend piper speci anesthet fish oleracea flower extract alreadi point fish anesthet | D000758;D000777;D019659;D031701 | T121;T061;T002;T039 |
36,228,288 | evalu chitosan silver nanoparticl isol pathogen mulberri silkworm bombyx mori l lepidoptera bombycida laboratori condit studi aim isol identifi certain bactrial fungal pathogn silkworm bombyx mori l promis chitosan plus silvr nanoparticl antimicrobi activ undr laboratori condit silkworm b mori hxkkxgxv bolgaria egg wer attain sricultur rsearch cntr giza governor egypt chitosan silvr nanoparticl matrial assembl laboratori biochmistri departmnt faculti agricultur al azhar univers cairo egypt herein total bactrial fungal isolatd xtrnal intern silkworm larva result mean percentag decreas weight elev diseas fifth instar compar fourth diseas instar addit two bactrial spci isolatd infectd larva identifi follow staphylococcus aurus enterococcus facali wherea thr fungal spci isolatd follow aspergillus flavus aspergillus tamarii beauveria bassiana transmiss elctron microscop imag demonstr morpholog proprti surfac appar silvr chitosan nanoparticl hav nar sphrical shap smooth surfac avrag particl size nm nm silvr chitosan nanoparticl recordd furthermor highst activ among nanoparticl test pathogn bacteria fungi isolatd idntifi studi rcordd chitosan gml sri whilst silvr nanoparticl xhibitd modrat antibacteri antifung activ | D012831;D048271;D007915;D053768;D031625 | T073;T002;T121;T109;T204 |
36,228,287 | nitrogen potassium synerg influenc yield qualiti dioscorea cayennensi studi aim evalu yield qualiti nematod incid chlorophyl content primari foliar macronutri yam respons nitrogen potassium fertil complet random block design use factori scheme x five nitrogen kg ha n five potassium dose kg ha ko four replic mass total commerci product tuber starch content ash leaf n p k content chlorophyl nematod incid evalu averag mass tuber obtain kg dose kg ha n kg ha ko dose kg ha n promot maximum total tuber product ha dose kg ha n kg ha ko result maximum product commerci tuber ha leaf n k starch ash content within standard yam incid meloidogyn scutellonema pratylenchus reduc increas simpl effect dose n ko maximum chlorophyl content obtain dose kg ha n nitrogen potassium interact despit antagonist effect accumul foliar p starch increas product averag mass commerci tuber consequ ensur profit yam cultiv | D027742;D009584 | T123;T168;T002;T196 |
36,228,286 | parasit rate plutella xylostella lepidoptera plutellida larva greenhous tetrastichus howardi hymenoptera eulophida femal differ densiti parasitoid control insect pest number per host affect effici object work evalu best densiti tetrastichus howardi olliff hymenoptera eulophida individu parasit fourth instar plutella xylostella linnaeus lepidoptera plutellida larva greenhous condit larva expos parasit howardi femal parasitoidhost ratio replic hour period larva kept host plant brassica oleracea pupa format tetrastichus howardi parasit reproduc p xylostella larva densiti test higher valu individu respect parasitoidshost nine howardi femal per p xylostella larva adequ number manag insect pest | D006927;D007915 | T204 |
36,228,285 | evalu antibacteri antifung activ antimicrobi soap soap play import role hygien health bactericid effect also remov dirt human bodi evalu effect soap antimicrobi activ differ commerci brand sold brazil test antimicrobi activ differ soap carri diffus agar microorgan staphylococcus aureus escherichia coli pseudomona aeruginosa enterobact cloaca acinetobact baumannii proteus mirabili candida albican commerci soap test transfer antimicrobi inhibit halo format aureus p aeruginosa bacteria two commerci soap inhibit speci baumannii c albican none seven product studi show inhibit e cloaca p mirabili e coli bacteria compar inform contain packag product result obtain survey diverg observ soap provid greater effici test microorgan present present becom use bacteria speci aureus p aeruginosa baumannii fungus speci c albican mark parallel sensit result opposit bacteria speci aureus p aeruginosa quantit variat inhibit halo diverg inform contain packag seven product studi result experiment test | D000890;D000935 | T121;T195 |
36,228,284 | analysi microbi divers root astragalus mongholicus dri root astragalus mongholicus therapeut effect tonif middl jiao replenish qi solidif surfac promot diuresi dispel sepsi outward nourish muscl slice black spot slice root astragalus divers endophyt fungi slice black spot normal slice analys paper endophyt fungal sequenc obtain high throughput sequenc otu subset obtain cluster belong phyla class order famili genera domin class eurotiomycet leotiomycet domin order eurotial helotial domin famili helotialesfamincertaesedi aspergillacea domin genera cadophora aspergillus peculiar fungal flora normal slice spot slice studi endophyt fungi divers astragalus slice provid help drug develop plant | D027885;D010944 | T002 |
36,228,283 | reproduct ecolog similar caretta caretta linnaeus eretmoch imbricata linnaeus southern bahia brazil studi evalu reproduct ecolog similar loggerhead sea turtl caretta caretta hawksbil sea turtl eretmoch imbricata two speci sea turtl southern coast bahia brazil two breed season octob april studi cover km area compos three beach pompilho itacarezinho patizeiro beach km long respect daili field survey perform day assess pattern studi speci use non metric multidimension scale order spearman correl analysi obtain oviposit pattern two speci moreov kruskal walli test perform review differ number hatchl three beach nmds prove speci similar ecolog perspect sinc three clear group term number hatchl three beach refer number nest negat correl observ two speci regard hatch activ speci three beach studi larger amount c caretta e imbricata hatchl found pompilho beach follow patizeiro itacarzinho find influenc manag strategi reduc anthropogen impact contribut conserv two endang sea turtl speci | D014426 | T014 |
36,228,280 | characteris neisseria meningitidi ccet variant whole genom sequenc neisseria meningitidi strain belong clonal complex caus numer outbreak epidem unit state canada europ account case meningococc diseas caus serogroup c worldwid brazil second frequent clonal complex within serogroup genet characteris ccet variant import epidemiolog monitor meningococc diseas identif circul epidem clone support specif action health surveil aim outbreak control | D008589;D009345 | T007;T047 |
36,228,275 | social scienc editor public health practic limit creation scientif habitus scientif publish social valu practic modul academ trajectori scientif journal oper two distinct social field editori scientif axi object intersubject relationship scientif field articl analyz perform social scienc editor field public health well concept process evalu scientif articl perspect relationship agent editori practic role shape scientif habitus methodolog option themat analysi semi structur interview editor chief associ social scienc area promin journal public health editor agent oper contradict pressur deriv productiv relat autonomi editori practic gradual creat editori habitus coin empir practic self taught train voluntari dedic also establish dialogu author peer competitor communiti field delimit object theme interest area legitimaci base disinterest action demand scientif field impos barrier articl consid low qualiti defin especi theoret methodolog gap lack origin howev didact work inculc way consid appropri manag theori methodolog social scienc limit refus text suggest import greater articul editor editor forum graduat program agent train research field | D035081;D011634 | T091;T170 |
36,228,274 | perceiv neighborhood characterist practic physic activ among adolesc young adult model distal outcom studi aim identifi neighborhood profil perceiv adolesc young adult estim associ global leisur time physic activ data individu age year taken cross section studi cluster sampl conduct citi state bahia brazil physic activ measur use intern physic activ questionnair ipaq short version addit question leisur activ percept characterist physic social environ neighborhood base scale question neighborhood profil defin latent class analysi lca estim effect physic activ use model distal outcom latent profil analysi result three neighborhood pattern describ urban sociabl favor physic activ class sociabl safe class insecur low sociabl class individu belong class show highest probabl exercis class percentag correspond respect statist signific associ identifi urban sociabl favor physic activ class whose chanc perform leisur activ ci neighborhood attribut favor practic physic activ exist urban element increas chanc activ leisur behavior among adolesc young adult use lca model distal outcom promis innov neighborhood approach | D007899;D000091542 | T056;T078;T080 |
36,228,273 | continu care care level experi user municip health network studi analyz experi user continu clinic manag care level cross section quantit studi use data survey conduct user public health network recif pernambuco state brazil experi continu clinic manag explor two dimens coher care access level care user present posit opinion coher care access regard coher care user report primari special care physician agre diagnosi treatment recommend primari care physician refer specialist necessari user report collabor physician solv health problem concern access user report long wait time consult specialist less half report delay primari care result studi coincid investig highlight need promot strategi achiev effect integr care network thus provid user greater continu health care | D003266;D003695 | T093;T058 |
36,228,272 | interfed consortium hospit manag brazilian unifi nation health system bahia state brazil decis make process light neo institut articl analyz decis interfed health consortium cis model altern manag hospit brazilian unifi nation health system sus bahia brazil agreement review semi structur interview conduct key actor central level bahia state health depart sesab cis northeast ii find analyz consid theoret framework neo institut emphas character histor polit institut context within sus actor involv decis make rule guidelin institut sesab cis result show decis predomin guid polit motiv state municip execut base purpos decentr manag health action servic region predomin action actor link govern incipi particip technic area sesab also converg theoret framework adopt rule guidelin inher institut sesab cis contribut adopt model element histor context also affect decis make process studi contribut better understand operation logic hospit care manag sus bahia multipl factor stimul develop new investig manag model sus reduct burden cost hospit admiss due neglect tropic diseas state | D006078;D006291 | T064;T089 |
36,228,271 | toward ethic care nurs home covid pandem qualit studi intern migrant chile intern migrant recogn popul risk context covid pandem worldwid various strategi deploy protect popul establish recept quarantin isol center articl report result studi explor experi intern migrant nurs home chile creat ensur safe quarantin covid pandem approach ethic condit care qualit studi carri thirti individu semi structur onlin interview conduct citi arica iquiqu antofagasta santiago intern migrant experi use nurs home health team nurs home manag nurs home local author nation expert themat analysi inform carri studi conclud intern migrant although experi nurs home meant signific health support essenti care provid addit requir frame approach right respect digniti person incorpor perspect intercultur work ensur right cultur relev health servic respect cultur individu minor peopl communiti | D000086382;D014171 | T098;T047;T067 |
36,228,270 | burden lung cancer attribut household air pollut chines femal popul trend analysi futur predict studi analyz long term trend burden lung cancer attribut household air pollut chines femal popul make predict next decad base data global burden diseas gbd joinpoint regress model use reflect tempor trend burden lung cancer attribut household air pollut autoregress integr move averag arima model use predict burden diseas next decad age standard mortal disabl adjust life year dali rate chines femal popul higher global rate gap due residenti radon increas time burden lung cancer attribut solid fuel shown signific downward trend due residenti radon increas slight overal remain lower former burden lung cancer increas age peak age dali rate chang year year model predict burden lung cancer attribut solid fuel gradual decreas next decad wherea burden lung cancer due residenti radon gradual increas surpass burden due solid fuel residenti radon becom import factor household air pollut solid fuel next decad chines femal popul futur intervent target household air pollut need reduc burden lung cancer | D000397;D008175;D011886 | T131;T191;T069;T196;T080 |
36,228,268 | epidemiolog studi lip oral caviti cancer brazil connect scienc clinic applic aim studi describ discuss epidemiolog indic lip oral caviti cancer brazil accord data global burden diseas data | D008046;D009062 | T191;T023 |
36,228,267 | effect berberin nois induc hear loss rat model nois induc hear loss prevent form hear loss serious social econom impact studi aim investig protect effect berberin potent antioxid anti inflammatori agent nois induc hear loss | D001599;D006317 | T121;T109;T037 |
36,228,266 | simpl method clinic implic pain comprehens geriatr assess effect chronic pain elder popul enorm term human suffer cost studi aim investig factor associ chronic low back pain older adult perform comprehens geriatr assess | D059350;D017116 | T047;T184 |
36,228,265 | role appar diffus coeffici measur differenti histolog subtyp brain metastasi lung cancer aim studi investig role appar diffus coeffici diffus weight imag differenti histolog subtyp brain metastasi lung cancer | D001932;D002289;D008175 | T191 |
36,228,264 | chang frequenc clinic featur acut rheumat fever covid era retrospect analysi singl center coronavirus diseas covid pandem result signific chang frequenc mani diseas studi aim investig chang frequenc clinic featur acut rheumat fever arf period determin effect health measur taken covid chang | D000086382;D012213 | T047;T067 |
36,228,263 | compar studi ripasa alvarado score geriatr patient diagnos acut append abdomin pain one preval reason seek medic attent diagnos elder adult acut append aa may difficult studi raja isteri pengiran anak saleha append ripasa alvarado rate evalu diagnost accuraci patient report emerg depart complain abdomin pain receiv surgeri aa | D001064;D012860 | T047;T013 |
36,228,262 | evalu qualiti life patient prematur ejacul lifelong acquir aim studi evalu qualiti life patient lifelong acquir prematur ejacul examin relationship depress anxieti | D007172;D061686 | T047;T048 |
36,228,261 | prognost valu tyg index hospit mortal nondiabet covid patient myocardi injuri purpos studi explor efficaci triglycerid glucos tyg index hospit mortal nondiabet coronavirus diseas covid patient myocardi injuri | D001786;D000086382 | T047;T109;T067 |
36,228,260 | comparison autonom nervous system dysfunct differ chronic spine disord neck pain versus low back pain studi aim compar heart rate variabl hrv patient chronic neck pain patient chronic low back pain correl chronic pain variabl heart rate variabl indic | D059350;D017116;D013122 | T047;T184 |
36,228,259 | evalu promot methyl status hypoxia factor interleukin gene express level mir b mir b childhood obes obes caus mani serious diseas increas exponenti childhood across world epigenet chang well genet play import role process adipogenesi therefor aim examin express level obes relat microrna b microrna b methyl status hypoxia factor interleukin gene associ obes children | D035683;D063766 | T047;T123;T033;T114 |
36,228,258 | protocol care foreign bodi ingest children qualit studi studi aim suggest care protocol foreign bodi ingest address clinic aspect identifi ingest object sever profession conduct | D005547;D005767 | T047;T072;T020;T037 |
36,228,257 | effect tumor diamet lymph node metastas suvmax valu prognosi limit stage small cell lung cancer studi design investig link surviv prognost factor tumor size lymph node metastasi metabol activ detect positron emiss tomographycomput tomographi patient limit stage small cell lung carcinoma | D001932;D008113;D008175;D055752 | T191 |
36,228,256 | predictor pain catastroph women system lupus erythematosus aim studi identifi predict factor associ pain catastroph women system lupus erythematosus sle | D058443;D008180 | T047;T041;T033 |
36,228,255 | system immun inflamm index novel predictor atrial fibril pump coronari arteri bypass graft studi aim examin predict role system immun inflamm index postop new onset atrial fibril patient undergo pump coronari arteri bypass graft | D001281;D047549 | T061;T047;T046 |
36,228,254 | role serum tube agglutin test monitor human brucellosi evalu post treatment sat titer posit result serum tube agglutin test persist treatment may interpret clinician treatment failur therefor studi examin valu serum tube agglutin test demonstr treatment success | D002006 | T047 |
36,228,253 | messag applic doctor patient relationship stressor aim studi assess use smartphon messag app stressor affect well gynecologist use tool communic patient | D002055;D010820 | T097;T048 |
36,228,252 | sexual function brazilian femal adolesc young adult cross section studi aim studi investig compar sexual function brazilian adolesc young women use popular contracept method | D004414 | T033 |
36,228,251 | adjunct corticosteroid therapi patient pulmonari tuberculosi tuberculosi treatment corticosteroid use adjuv especi meningealpericardi tuberculosi form diseas especi sever tuberculosi requir mechan ventil use controversi aim present studi assess whether use corticosteroid treatment pulmonari tuberculosi patient mechan ventil associ hospit mortal | D014376;D014397 | T047 |
36,228,250 | mutagen damag among bronchiectasi patient attend pulmonolog sector hospit southern brazil bronchiectasi chronic respiratori diseas character inflamm irrevers dilat bronchi recurr pulmonari infect high morbid mortal rate less studi point view preval associ factor direct relat respiratori prognosi diseas relat exacerb inflammatori process oxid stress studi search investig micronucleus frequenc patient without bronchiectasi treat special pulmonolog servic hospit extrem south brazil | D001987;D015272 | T047;T091 |
36,228,249 | import epicardi adipos tissu predictor heart failur preserv eject fraction epicardi adipos tissu special form viscer fat surround heart associ cardiac metabol diseas epicardi adipos tissu associ risk factor heart failur preserv eject fraction obes metabol syndrom hypertens diabet studi examin import epicardi adipos tissu predictor heart failur preserv eject fraction | D006333 | T047;T046 |
36,228,248 | behaviour intent hand hygien complianc averag ecuadorian hospit studi aim character hand hygien behaviour intent hospit servic cluster medium size hospit ecuadorian citi | D003428;D063373 | T055;T047 |
36,228,247 | quantif cell free circul mitochondri dna copi number variat hepatocellular carcinoma hepatocellular carcinoma common primari malign liver tumor mitochondri dna copi number shown associ various malign howev studi absolut quantif mtdna copi number hepatocellular carcinoma aim studi develop new method absolut quantif mtdna copi number relat quantifi variat mtdna copi number hepatocellular carcinoma patient comparison healthi individu | D006528;D008113 | T191 |
36,228,238 | effect foveal herniat surgic outcom patient idiopath epiretin membran studi aim compar anatom visual outcom idiopath epiretin membran peel surgeri without foveal herniat | D019773 | T047;T020 |
36,228,237 | factor associ risk relat use psychoact substanc men depriv liberti evalu factor associ risk relat use psychoact substanc male inmat prison citi south brazil | D011329;D019966 | T098;T048;T033 |
36,228,236 | effect supplement oxygen prevent surgic site infect systemat review meta analysi assess effect supplement oxygen high fio compar convent fio prevent surgic site infect | D015179;D013530 | T191;T046 |
36,228,235 | covid pandem vaccin abandon children spatial heterogen map identifi spatial cluster correspond abandon routin vaccin children | D000086382;D011051;D022243 | T047;T116;T121;T129;T067 |
36,228,234 | resili reduct occup stress nurs analyz associ resili occup stress nurs profession general hospit | D000073397;D055500 | T054;T055;T048;T033 |
36,228,232 | hiv knowledg correl undetect untransmitt slogan brazil knowledg hiv transmiss prevent necessari step adopt prevent behavior assess hiv knowledg correl perceiv accuraci undetect untransmitt uu slogan onlin sampl adult brazilian overal particip show high hiv knowledg level perceiv accuraci uu slogan signific correl hiv knowledg younger particip report lower incom lower educ never test hiv show poorer hiv knowledg fill gap knowledg among specif popul urgent order increas prevent behavior decreas hiv stigma | D015658 | T047 |
36,228,231 | hospit advers drug event brazilian unifi health system ten year retrospect analysi routin data describ frequenc characterist hospit forwith advers drug event brazilian unifi health system routin data | D064420;D006760 | T058;T046;T037 |
36,228,230 | mortal inequ measur socioeconom indic brazil scope review summar literatur relationship composit socioeconom indic mortal differ geograph area brazil | D012923;D013405 | T098;T080;T033 |
36,228,229 | phytoremedi toxic heavi metal pollut soil water dargai district malakand khyber pakhtunkhwa pakistan contamin natur resourc heavi metal releas steel mill primari caus soil water pollut dargai malakand locat northern side pakistan therefor present studi aim determin level heavi metal soil water sampl area wild plant grow nine nativ plant pteri vittata populus nigra eucalyptus camaldulensi persicaria maculosa arundo donax xanthium strumarium verbascum thapsus ricinus communi parthenium hysterophorus test phytoremedi capabl environment friend general util low cost approach elimin heavi metal pollut soil water soil water effluent sampl taken contamin site seven steel mill dargai district malakand subject heavi metal analysi base bioconcentr factor bcf transloc factor tf calcul highest bcf zinc record pteri vittata root lowest valu observ verbascum thapsus leav pteri vittata root show highest bcf iron ricinus communi leav show lowest highest bcf valu chromium highest populus nigra root lowest valu record persicaria maculosa leav select metal fe zn cr highest tf record pteri vittata verbascum thapsus xanthium strumairum respect therefor recommend plant grown near steel mill reclaim heavi metal industri effluent pollut soil well pollut water | D019216;D012989 | T131;T196 |
36,228,228 | determin genet divers acacia modesta germplasm use sds page biochem marker protein import determin genet divers among plant speci given popul turn import breeder farmer easili select appropri varieti grow given local connect present studi aim evalu genet divers acacia modesta germplasm sodium dodecyl sulphat polyacrylamid gel electrophoresi sds page techniqu genotyp subject sds page analysi total polypeptid band observ electrophoretogram monomorph remain polymorph variat found b respect locus contribut toward genet disagr cluster analysi sort genotyp cluster genotyp one cluster ident regard protein profil show less intra specif genet variat wherea differ find genotyp | D000045;D007887 | T002 |
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