PMID
int64 35.7M
36.4M
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36,319,678
|
knowledg attitud practic dengu prevent dengu sustain hotspot non sustain hotspot singapor cross section studi dengu sustain hotspot shs result signific public health burden studi aim compar knowledg attitud practic kap score shs non sustain hotspot nshs identifi describ gap factor associ kap dengu prevent among shs resid resid singapor cross section studi conveni sampl conduct use digit survey random select shs nshs residenti area consist resid age older resid exist hous unit chi squar test test use comparison analysi categor continu variabl respect total respond complet self administ anonym survey signific differ mean score knowledg shs vs nshs p attitud shs vs nshs p practic shs vs nshs p section signific shs associ factor identifi age group year old ci malay ci secondari school educ ci privat condominium ci resid household unit year ci respond know mosquito breed open contain stagnant water ci disagre reduc aed mosquito way prevent dengu ci go clinichospit even without sever symptom ci independ factor associ dengu sustain hotspot may influenc risk dengu transmiss residenti area
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D003715;D000330
|
T047;T204
|
36,319,677
|
measur chang blood volum fraction induc gingiv healthi unhealthi popul use hyperspectr spatial frequenc domain imag clinic studi investig aim quantit measur chang inflamm subject healthi unhealthi gum period induc gingiv total subject healthi gum inflamm enlist given oral exam dental hygienist baselin measur acquir week period oral hygien abstin loben modifi gingiv index score use inflamm score hyperspectr spatial frequenc domain imag use quantit measur oxi deoxygen blood volum fraction two time point baselin week oral hygien abstin found abstain oral hygien caus near proport increas oxygen deoxygen blood volum fraction healthi individu individu start studi mild moder gingiv increas blood volum main due deoxygen blood
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D005891
|
T047
|
36,319,676
|
cost effect analysi singl sequenti test strategi tuberculosi infect adult live hiv unit state tuberculosi infect tbi frequent progress tuberculosi tb diseas peopl co infect human immunodefici virus hiv examin cost effect singl sequenti test total strategi tbi hiv infect peopl perspect us healthcar provid decis analyt model year timefram construct simul tb relat outcom direct medic cost qualiti adjust life year qali base case analysi confirm negat tst follow qft plus strategi gain qali total cost usd probabilist sensit analysi mont carlo simul probabl confirm negat tst follow qft plus accept cost effect highest strategi willing pay threshold exceed usdqali conclus strategi confirm negat tst follow qft plus appear prefer cost effect option tbi test hiv infect peopl us healthcar provid perspect
|
D055985;D014376;D015658
|
T047
|
36,319,674
|
morphometr imag biomark identifi alzheim diseas even among mix dementia patient definit diagnosi alzheim diseas ad even presenc co morbid neuropatholog occur ad case signific unmet medic need obstruct discoveri effect ad therapeut ad biomark morphometr imag mi assay cultur skin fibroblast use doubl blind allcom age trial patient cohort ad dementia patient n autopsi confirm non ad dementia patient n autopsi genet confirm non dement control ahc patient n fibroblast cell isol mm skin punch biopsi cultur matrigel matrix movement dynam quantifi imag analysi count aggreg n pre defin field imag measur averag area aggreg per imag number area ratio natur logarithm form ln determin patient sampl ad cell line form fewer larg aggreg cell cluster togeth non ad ahc cell line cut valu ln determin biomark valu non dement appar healthi control ahc case unequivoc valid autopsi genet andor dementia criteria possibl patient sampl sampl collect multipl center four us center one center japan studi found effect center center variat fibroblast isol cell growth cell aggreg valu ln autopsi confirm mi biomark distinguish ad non ad dementia non add patient correct diagnos ad even presenc co morbid patholog autopsi true posit fals negat fals posit true negat accuraci sensit specif calcul ci find mi assay appear detect ad great accuraci even abund co morbid
|
D000544
|
T047;T048
|
36,319,673
|
explor natura habitat satellit imag segment combin phytosociolog data case studi ierni balog area central slovakia natura network protect area cover europ valuabl threaten speci habitat recent biota belong network threaten climat chang various human impact regular monitor need ensur effect protect proper manag measur site habitat convent field approach often time consum inaccur new approach studi differ focus result develop approach includ point data field research phytosociolog databas start point automat segment develop recent novel method could help connect ground base remot sens data case studi locat central slovakia mountain around villag ierni balog main aim case studi appli advanc remot sens techniqu map area condit veget unit focus forest habitat belong main natura network concentr verif possibl differenti various habitat use multispectr sentinel satellit data softwar naturasat creat team use reach object collect data field use phytosociolog approach segment explor area program naturasat spectral characterist calcul within identifi habitat use softwar tool subsequ process test statist obtain signific differ forest habitat type also segment accuraci test compar close planar curv ground base file data softwar result provid promis result valid method use result studi potenti use wider area map occurr qualiti natura habitat
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D003247;D017753
|
T078;T070;T082;T069;T081;T064
|
36,319,672
|
product mous offspr zygot fertil freez dri spermatid mous clone nuclear transfer use freez dri fd somat cell possibl success rate signific lower fd spermatozoa spermatozoa unlik somat cell haploid cell harden nuclei due protamin factor respons toler fd treatment remain unclear studi attempt produc offspr fd spermatid haploid sperm progenitor cell whose nuclei like somat cell yet replac protamin develop method collect fd spermatid testicular suspens despit signific lower success rate fd spermatozoa healthi offspr obtain fd spermatid inject oocyt offspr also obtain fd spermatid deriv immatur male mice yet produc spermatozoa result suggest nuclear protamin rather haploid nuclei one key process respons toler fd treatment
|
D013087;D012662
|
T058;T059;T025;T031
|
36,319,671
|
compar transcriptom wgcna reveal key gene involv lignocellulos degrad sarcomyxa eduli development transcriptom sarcomyxa eduli assess explor molecular mechan under lignocellulos degrad six stage analyz span entir development process growth mycelium occupi half bag b mycelium low temperatur stimul occupi entir bag b appear mycelium primordia b primordia b mycelium harvest stage b matur fruit bodi b sampl six development stage use transcriptom sequenc three biolog replic experi co express network weight gene associ extracellular enzym physiolog trait construct use weight gene co express network analysi wgcna obtain gene co express modul signific associ lignocellulos degrad addit key gene kind tf famili involv lignocellulos degrad pathway discov four modul exhibit highest correl target trait result provid new insight advanc understand molecular genet mechan lignocellulos degrad eduli facilit util edibl mushroom industri
|
D059467;D000363
|
T081;T004;T086
|
36,319,668
|
cellular adapt lead coral fragment attach artifici substrat acropora millepora cam reproduct propag asexu fragment reef build coral acropora millepora depend success attach reef substrat modif soft tissu perman bond skelet encrust despit decad research examin asexu propag coral initi respons cellular reorganis develop lead fragment substrat attach via newli form skeleton document entireti establish first coral attach model speci cam develop novel method allow correl fluoresc electron microscopi imag data vivo microscop time laps imageri multi scale imag approach identifi three distinct phase involv asexu propag contact respons coral fragment contact substrat follow fragment stabilis anchor soft tissu format lappet like appendag structur lead substrat bond tissu encrust onset skelet calcif develop cam provid new biolog insight enabl reef research manag coral restor practition begin evalu attach effect need optimis speci substrat compat achiev effect outplant
|
D037421
|
T204
|
36,319,667
|
influenc mate strategi semin materi invest crab reproduct involv high energet cost relat behaviour gamet product femal energi alloc gamet product well document howev estim male invest semin materi scarc present studi aim assess compar male invest four brachyuran speci determin biochem substrat present vasa deferentia subsequ estim energet invest reproduct cycl identifi two group contrast energi invest two speci homalaspi plana romaleon setosum show high invest due signific quantiti protein lipid speci characteris larg complex vasa deferentia format remark larg sperm plug deposit femal copul sperm competit avoid strategi contrast metacarcinus edwardsii taliepus dentatus invest littl energi smaller size simpler vasa deferentia morpho function trait may play key role determin invest may also influenc mechan ie mate tactic prevent sperm competit intens polygyni studi emphasis high amount energi male invest semin materi highlight divers mate strategi brachyura reflect even physiolog level
|
D003386
|
T204
|
36,319,664
|
method quantit apoplast hydrat arabidopsi leav reveal water soak activ effector pseudomona syringa biotrophi plant apoplast crucial role photosynthesi respir due vital function gas exchang transpir apoplast also dynam environ particip mani ion nutrient transport process via plasma membran local protein furthermor divers microb colon plant apoplast includ hemibiotroph bacteri pathogen pseudomona syringa pv tomato pto strain dc pto dc initi pathogenesi upon move stomata apoplast prolifer high level develop centrifug base method isol quantifi apoplast fluid arabidopsi leav without signific damag tissu appli simpl apoplast extract method demonstr pto dc type iii bacteri effector avr hopm induc hydrat arabidopsi apoplast advanc macroscop water soak disrupt host cell integr diseas progress final demonstr util apoplast extract method isol bacteria prolifer apoplast
|
D017360;D018551
|
T168;T002
|
36,319,663
|
host microbiom interact gut liver axi connect organ understand connect gut microbiom liver provid import insight pathophysiolog liver diseas sinc gut microbi dysbiosi increas gut permeabl metabolit biosynthes reach liver portal circul affect hepat immun inflamm immun cell activ metabolit also reach liver lymphat circul liver influenc immun metabol multipl organ bodi includ gut releas bile acid metabolit biliari tract enter system circul review bidirect communic gut liver molecular cross talk host microbiom discuss review also provid detail intric level communic role microbiom gut liver brain gut liver kidney gut liver lung gut liver heart axe observ indic complex network interact host organ influenc gut microbiom
|
D064806;D000069196
|
T047;T046;T001;T007
|
36,319,662
|
develop evalu tripl gene transgen cotton line express three gene cryac cryab epsp lepidopteran insect pest herbicid toler cotton intern agricultur commod main cash crop pakistan qualiti quantiti subject various whim natur climat chang insect pest complex weed reduc product develop tripl gene cotton contain epsp gene along two bt toxin gene cryac cryab use strategi three gene clone dna follow success cotton transform via agrobacterium mediat transform strategi develop help cotton breeder develop new cultivar incorpor gene non transgen singl bt cryac gene cotton background three gene inherit togeth express three protein confirm immunostrip quantifi enzym link immunosorb assay elisa spatio tempor express bt protein differ part tripl gene nibg cotton plant determin maximum express found leav follow seed boll rind insect bioassay cotton bollworm helicoverpa armigera armyworm spodoptera litura pink bollworm pectinophora gossypiella show mortal best perform line nibg e basi spatiotempor express glyphos assay insect mortal data use event character use genom sequenc approach event success character name nibg diagnost test base event specif pcr develop abil distinguish nibg event commerci transgen cotton event confirm confirm stabl express three protein field condit homozyg transgen line grown field express confirm immunostrip assay found three gene express field condit show three gene inherit togeth upon cross local elit cotton line f generat grown glasshous field condit express three gene confirm field condit result show transgen cotton three gene clone dna express gene conveni transfer elit cotton line singl cross
|
D006540;D009036
|
T131;T204
|
36,319,661
|
predict walk work use street level imageri deep learn seven canadian citi new big data stream street level imageri offer unpreced possibl develop health relev data urban environ urban environment featur deriv street level imageri use assess pedestrian friend neighbourhood design predict activ commut studi conduct canada use million googl street view gsv imag seven canadian citi appli imag segment object detect comput vision method extract data person bicycl build sidewalk open sky without tree build veget postal code associ urban featur walk work rate obtain canadian census assess also assess gsv deriv urban featur perform predict walk work rate relat wide use walkabl measur result show featur deriv street level imag better abl predict percent peopl walk work primari mode transport compar data deriv tradit walkabl metric given increas coverag street level imageri around world consider potenti machin learn comput vision help research studi pattern activ transport health relat behaviour exposur
|
D004779;D000077321
|
T078;T066
|
36,319,660
|
health risk consum sphoeroid spp navachist lagoon complex due trace metal organochlorin pesticid content navachist complex nav impact neighbor human activ locat southwestern coastal zone gulf california studi determin trace metal tm organochlorin pesticid ocp health risk content edibl tissu sphoeroid spp nav daili intak edi target hazard quotient thq hazard index hi carcinogen non carcinogen risk calcul twenti ocp seven tm detect cd cu fe mn pb zn mrls chlordan frequent ocp highest averag concentr hch follow chlordan high ratio hch p p ddd p pddd absenc p p ddt higher ratio dieldrin endrin aldrin chlordan chlordan heptachlor heptachlor epoxid indic histor contamin contrast residu product methoxychlor endosulfan isom indic endosulfan recent use tm edi thq g day ilcr minimum level show high risk potenti cancer develop long term
|
D006843;D010575;D014131
|
T121;T123;T109;T131;T196
|
36,319,659
|
two step pre process tool remov gaussian ectop nois heart rate variabl analysi artifact electrocardiogram ecg degrad qualiti record signal conduc heart rate variabl hrv analysi two type nois often found ecg record technic physiolog artifact current preprocess method primarili attend ectop beat consid technic issu affect ecg secondari aim studi investig effect increas increment artifact use hrv measur two step preprocess approach denois hrv introduc target type nois separ first technic artifact ecg elimin appli complet ensembl empir mode decomposit adapt nois second step remov physiolog artifact hrv signal use combin filter singl depend rank order mean adapt filter algorithm perform two step pre process tool show high correl coeffici rmse valu ad ectop beat db gaussian nois hrv measur studi except hf peak lf peak signific affect type nois frequenc measur total power hf power lf power fragment measur pas pip pss sensit type nois
|
D012815;D004562
|
T060;T074;T066
|
36,319,658
|
explain analyt understand caus correct error achiev increas perfect accuraci natur distinguish pattern addit pursu accur analyt invalu clarifi inaccuraci exist propos transpar classif tc method train data consist posit negat observ obtain posit pattern find intersect two posit observ negat pattern obtain manner next pure posit pure negat pattern establish select pattern appear one type test pure posit pure negat pattern use score observ next observ classifi posit posit score zero posit negat score zero otherwis classifi negat experi tc identifi posit eg malign observ low ratio train test data eg use breast cancer wisconsin origin use contracept method choic without fine tune paramet random select uncertainti methodolog elimin use tc tc visual caus therefor predict error network traceabl correct furthermor tc show potenti identifi whether ground truth incorrect eg identifi diagnost error
|
D001943
|
T191
|
36,319,657
|
toward high effici nir ii respons convers phosphor enabl long lifetim er second near infrar nir ii respons photon convers uc materi show great applic prospect field biolog optic communic howev still enorm challeng obtain effici nir ii respons materi herein develop seri er dope ternari sulfid phosphor high effici uc emiss nm irradi nay er achiev visibl uc effici high along high bright spectral stabil light illumin temperatur effici uc domin excit state absorpt accompani advantag long lifetim ms ms excit state level er instead well recogn energi transfer uc sensit activ nay er phosphor develop high perform underwat communic narrowband nir photodetector find suggest novel approach develop nir ii respons uc materi simul new applic eg simultan nir visibl optic communic
|
D004735
|
T044
|
36,319,655
|
non fast chang hs crp level chines patient coronari heart diseas daili meal high sensit c reactiv protein hs crp key inflammatori factor atherosclerot cardiovascular diseas chines patient coronari heart diseas chd chang hs crp level daili meal effect statin never explor total inpati chd includ studi hs crp level measur fast non fast state h h daili breakfast inpati divid two group accord fast hs crp mgl group fast hs crp mgl signific higher percentag patient statin use month admiss fast hs crp mgl vs p hs crp level increas signific non fast state two group p mgl came fast hs crp mgl conclus hs crp level increas signific chd patient daili meal suggest non fast hs crp level could better paramet evalu inflamm state chd patient rather fast hs crp level
|
D019161;D003327
|
T121;T047;T109
|
36,319,653
|
rest state bold signal variabl associ individu differ metacontrol numer studi demonstr moment moment neural variabl behavior relev benefici task behavior requir cognit flexibl howev remain unclear whether posit effect neural variabl also hold cognit persist moreov differ brain variabl measur use previous studi yet comparison lack current studi examin associ rest state bold signal variabl two metacontrol polici ie persist vs flexibl brain variabl estim rest state fmri rsfmri data use two differ approach ie standard deviat sd mean squar success differ mssd metacontrol bias assess three metacontrol sensit task result show brain variabl measur sd mssd high posit relat critic higher variabl measur mssd attent network pariet frontal network frontal acc network pariet motor network higher variabl measur sd pariet motor network pariet frontal network associ reduc persist greater flexibl metacontrol ie larger stroop effect wors rat perform result show benefici effect brain signal variabl cognit control depend metacontrol state involv studi highlight import tempor variabl rsfmri activ understand neural underpin cognit control
|
D001931;D007206
|
T062;T060;T054
|
36,319,652
|
effect immunomodulatori therapi patient repeat implant failur systemat review network meta analysi meta analysi analyz clinic pregnanc outcom repeat implant failur rif patient treat immunomodulatori therapi public publish august identifi search pubm embas web scienc databas qualiti studi evalu cochran bias risk assess tool network meta analysi perform stata outcom clinic pregnanc rate cpr live birth rate lbr implant rate ir result network meta analysi rcts includ particip show pbmcs prp sc gcsf signific improv cpr compar lmwh pbmcs ci prp ci sc gcsf ci lbr prp signific higher iu gcsf ci lmwh ci intralipid ci lbr pbmcs also signific better lmwh ci furthermor prp treatment signific improv ir compar lmwh treatment ci limit evid exist rcts suggest pbmcs prp best therapeut option rif patient howev owe quantiti limit top qualiti research requir obtain addit high level evid
|
D006495;D010064
|
T121;T040;T109
|
36,319,651
|
compar hydrodynam characteris two hydroxyl polym base pinen oleic acid deriv monom potenti use archaeolog consolid oseberg vike ship burial one extens collect vike wooden artefact ever excav norway earli twentieth centuri mani artefact treat alum order preserv inadvert lead current degrad state therefor crucial develop new bioinspir polym could use conserv artefact prevent disintegr two hydroxyl polym synthesis tpa tpa use pinen oleic acid deriv monom functionalis acryl moieti characteris use biomolecular hydrodynam analyt ultracentrifug high precis viscometri shown polym properti would potenti make good wood consolid conform analys viscos increment univers hydrodynam paramet ellip softwar show polym extend conform facilit situ network appli wood sedfit mstar analys sediment equilibrium data indic weight averag molar mass w kda kda tpa tpa respect analys sedfit sediment veloc multisig howev reveal tpa much greater homogen lower proport aggreg studi suggest polym particular tpa characterist suitabl wood consolid optim molar mass conform hydroxyl natur make interest lead research
|
D057446;D011108
|
T104;T122;T070
|
36,319,650
|
slope stabil analysi consid strength anisotropi c soil tradit slope stabil analys soil usual approxim isotrop howev natur cohes soil deposit inher anisotrop primarili due direct arrang soil particl deposit process paper general anisotrop constitut model c soil introduc evalu influenc vari shear strength slope stabil model initi strength anisotropi defin varieti friction angl direct principl stress model util two approach estim slope stabil first upper bound limit analysi solut slope stabil develop safeti factor slope studi second model coupl finit element method get insight influenc anisotropi slope stabil one typic slope case slope studi numer analys found slope stabil larg overestim strength anisotropi ignor overestim term safeti factor reach complex interrel degre anisotropi evolut ensu safeti factor reveal seri parametr studi term differ degre anisotropi
|
D012987
|
T167
|
36,319,649
|
janus regul ice growth hyperbranch polyglycerol generat dynam hydrogen bond studi new phenomenon describ janus effect ice growth hyperbranch polyglycerol align surround water molecul identifi even ident polyglycerol induc inhibit ice growth recrystal also promot growth rate ice twice pure water investig polym architectur popul found stark differ generat quasi structur h molecul icewat interfac play crucial role outcom opposit effect inhibit activ induc polym near fix loci form steadi hydrogen bond ice surfac howev format dissoci dynam interfaci hydrogen bond origin maintain migrat polym result enhanc quasi liquid layer facilit ice growth ice growth activ uniqu properti unseen natur antifreez protein mimet materi
|
D007053;D011108
|
T104;T197;T122
|
36,319,648
|
genom insight local adapt futur climat induc vulner keyston forest tree east asia rapid global climat chang pose substanti threat biodivers assess popul vulner adapt capac climat chang crucial inform conserv mitig strategi generat chromosom scale genom assembl sequenc genom individu collect popul populus koreana pioneer keyston tree speci temper forest east asia integr popul genom environment variabl reveal set climat associ singl nucleotid polymorph insertiondelet structur variat especi numer adapt non code variant distribut across genom incorpor variant environment model scheme predict high spatiotempor shift speci respons futur climat chang identifi vulner popul need conserv prioriti mani candid gene variant may use forest tree breed special aim find highlight import integr genom environment data predict adapt capac key forest rapid climat chang futur
|
D014197;D000069600
|
T040;T002
|
36,319,647
|
design implement virtual fit system base gestur recognit cloth transfer algorithm virtual fit bring fast conveni fit experi peopl two core problem virtual fit system human comput interact cloth simul interact import factor determin fit experi previous virtual fit product usual use mous keyboard interact user rare good sens substitut interact method use multipl camera take user imag differ angl carri postur recognit defect low recognit accuraci view cloth simul human comput interact virtual fit system order achiev better custom immers experi paper implement real time interact virtual fit system base microsoft kinect motion sens devic propos gestur determin algorithm base finger recognit imag transfer algorithm base skeleton inform match use openni develop librari multi thread technolog develop motion sens captur modul complet real time virtual fit system system test result show good user experi
|
D005868;D014584
|
T170;T054
|
36,319,643
|
foxq recruit mll complex activ transcript emt promot breast cancer metastasi aberr express forkhead box transcript factor foxq preval mechan epitheli mesenchym transit emt metastasi multipl carcinoma type howev remain unknown foxq regul gene express report foxq initi emt recruit mllkmt histon methyltransferas complex transcript coactiv first establish foxq promot recognit preced mll complex assembl histon lysin trimethyl within promot region critic gene emt program mechanist identifi forkhead box foxq function transactiv domain direct bind mll core complex subunit rbbp without interrupt foxq dna bind activ moreov genet disrupt foxq rbbp interact pharmacolog target kmtmll recruit inhibit foxq depend gene express emt vivo tumor progress studi suggest target foxq mll epigenet axi could promis strategi combat tripl negat breast cancer metastat progress
|
D001943;D016609
|
T191
|
36,319,642
|
dna read count calibr singl molecul long read sequenc mani applic quantit inform dna mixtur differ molecular length import gene therapi vector much longer sequenc individu via short read ngs howev vector prepar may contain smaller dnas behav differ sequenc use two librari prepar pacif biosystem pacbio oxford nanopor technolog ngs determin suitabl quantit assess vari size dnas equimolar length standard generat e coli genom dna pacbio librari prepar provid consist length depend though complex pattern method suffici sensit differ genom copi number dna e coli grown exponenti stationari phase condit could detect transposas base oxford nanopor librari prepar provid predict length depend random sequenc start caus loss origin length inform ligat base approach retain length inform read frequenc variabl model e coli versus lambda read frequenc via cubic spline smooth show shorter genom could use suitabl intern spike dnas bp kb rang allow meaning qc carri aav prepar
|
D059014;D004926
|
T063;T007;T059
|
36,319,640
|
hiv rev rre function activ primari isol high depend minim context depend chang rev hiv infect intron contain viral mrnas export cell nucleus cytoplasm complet replic cycl cellular restrict export incomplet splice transcript overcom viral protein rev rna structur found unsplic incomplet splice viral mrnas rev respons element rre primari hiv isol display substanti variat sequenc function activ rev protein analyz rev two primari isol dispar activ result differ vitro fit replic compet viral construct result show amino acid differ within oligomer domain arginin rich motif nuclear export signal determin level rev activ two specif amino acid substitut suffici alter low activ rev high activ phenotyp mutat rev sequenc unpredict effect activ differ two rev backbon sensit rev function level small sequenc chang like permit modul rev rre activ hiv infect may play role pathogenesi function consequ rev mutat differ primari isol highlight challeng general studi rev conduct use laboratori hiv strain
|
D015497;D015658;D006679
|
T005;T034;T047
|
36,319,638
|
unsupervis learn age principl longitudin data age lead risk factor preval diseas death howev relat age relat physiolog chang lifespan poor understood combin analyt machin learn tool describ age process larg set longitudin measur assum age result dynam instabl organ state design deep artifici neural network includ auto encod auto regress ar compon ar model tie dynam physiolog state stochast evolut singl variabl dynam frailti indic dfi subset blood test mous phenom databas dfi increas exponenti predict remain lifespan observ limit dfi consist late life mortal deceler dfi chang along hallmark age includ frailti index molecular marker inflamm senesc cell accumul respond life shorten high fat diet life extend rapamycin treatment
|
D000073496
|
T033;T184;T046
|
36,319,637
|
unequ airborn exposur toxic metal associ race ethnic segreg usa person color expos disproportion burden air pollut across unit state decad yet inequ exposur known toxic element air pollut unclear find popul live racial segreg communiti expos form fine particul matter three time higher mass proport known toxic carcinogen metal concentr total fine particul matter two time higher racial segreg communiti concentr metal anthropogen sourc near ten time higher popul live racial segreg communiti disproportion expos environment stressor throughout past decad find evid howev disproportion exposur may abat though target regulatori action exampl recent regul marin fuel oil reduc vanadium concentr coastal citi also sharpli lessen differ vanadium exposur segreg
|
D000393;D000397
|
T131;T069;T080
|
36,319,635
|
analyt comput workflow depth analysi oxid complex lipid blood plasma lipid structur divers class biomolecul undergo varieti chemic modif among lipid per oxid attract attent due signific regul inflamm cell prolifer death program despit appar regulatori signific molecular repertoir oxid lipid remain larg elus accur annot lipid modif complic low abund often unknown biolog context depend structur divers provid workflow base combin bioinformat lc msms technolog support identif relat quantif oxid complex lipid modif type posit specif manner develop methodolog use identifi epilipidom signatur lean obes individu without type diabet characterist signatur lipid modif lean individu domin presenc modifi octadecanoid acyl chain phospho neutral lipid drastic shift toward lipid peroxid driven accumul oxid eicosanoid suggest signific alter endocrin signal oxid lipid metabol disord
|
D053719;D003924
|
T063;T047
|
36,319,634
|
profilin regul dna replic fork context depend fashion interact snfh bodl dna replic fork tight control larg protein network consist well known core regul mani accessori factor remain function undefin studi report previous unknown nuclear function actin bind factor profilin pfn dna replic occur context depend fashion requir bind poli l prolin plp contain protein instead actin unperturb cell pfn increas dna replic initi acceler fork progress bind stimul plp contain nucleosom remodel snfh replic stress pfnsnfh increas fork stall function collabor fork revers enzym enabl resect unprotect fork addit pfn bind function attenu plp contain fork protector bodl increas resect subset stress fork accord rais nuclear pfn level decreas genom stabil cell surviv replic stress thus pfn multi function regul dna replic exploit anticanc potenti
|
D000199;D051304
|
T123;T116
|
36,319,633
|
monkeypox epidemiolog pathogenesi treatment prevent monkeypox zoonot diseas endem west central africa caus monkeypox virus howev case recent confirm mani nonendem countri outsid africa declar ongo monkeypox outbreak public health emerg intern concern juli context covid pandem rapid increas number confirm case could pose threat intern communiti review epidemiolog monkeypox monkeypox virus reservoir novel transmiss pattern mutat mechan viral infect clinic characterist laboratori diagnosi treatment measur addit strategi prevent vaccin smallpox vaccin also includ current epidemiolog data indic high frequenc human human transmiss could lead outbreak especi among men sex men develop antivir drug vaccin monkeypox virus urgent need despit therapeut effect current use drug clinic provid use inform improv understand monkeypox virus give guidanc govern relat agenc prevent control spread monkeypox virus
|
D045908;D000086382;D000072339
|
T047;T098;T067
|
36,319,632
|
small molecul assist assembl multifunct ceria nanozym synergist treatment atherosclerosi consid intravascular reactiv oxygen speci ros inflamm two characterist featur atherosclerot microenviron develop appropri strategi treat atherosclerosi synergist regul ros inflamm attract widespread attent herein special molecul zoledron acid contain imidazol bisphosphon group select first time assist assembl cerium ion produc function ceria zoledron acid nanocomposit cz ncs serv new carrier differ kind drug eg probucol pb also exert effici multienzym activ achiev collabor therapi import platelet membran coat biomimet nanoplatform pcz pb ncs specif accumul inflammatori atherosclerot lesion synergist regul ros level inflamm effici inhibit foam cell format novel assembl method also appli treatment mani diseas associ oxid stress inflamm
|
D053758;D050197
|
T047;T046;T073
|
36,319,631
|
usf mediat upregul txnrd contribut hepatocellular carcinoma progress activ aktmtor signal thioredoxin reductas txnrd one major redox regul mammalian cell report involv tumorigenesi howev role regulatori mechan under progress hcc remain poor understood studi demonstr txnrd signific upregul hcc tumor tissu correl poor surviv hcc patient function studi indic txnrd knockdown substanti suppress hcc cell prolifer metastasi vitro vivo overexpress show opposit effect mechanist txnrd attenu interact trx pten result acceler pten degrad therebi activ aktmtor signal target gene confer elev hcc cell mobil metastasi moreov usf identifi transcript suppressor txnrd direct interact two e box site txnrd promot usf function tumor suppressor downstream repress txnrd clinic data reveal negat co express correl usf txnrd conclus find reveal usf mediat upregul txnrd contribut hepatocellular carcinoma progress activ aktmtor signal
|
D006528;D008113
|
T191
|
36,319,629
|
field measur reveal exposur risk microplast ingest filter feed megafauna microparticl microplast microfib ubiquit marin food web filter feed megafauna may extrem risk exposur microplast neither amount pathway microplast ingest well understood combin depth integr microplast data california current ecosystem high resolut forag measur tag deploy blue fin humpback whale quantifi plastic ingest rate rout exposur find baleen whale predomin feed depth coincid highest measur microplast concentr pelag ecosystem near microplast ingest predict occur via trophic transfer predict fish feed whale less expos microplast ingest krill feed whale per day krill oblig blue whale may ingest million piec microplast fish feed humpback whale like ingest piec microplast speci struggl recov histor whale alongsid anthropogen pressur find suggest cumul impact multipl stressor requir attent
|
D050640;D033201;D014874
|
T131;T015;T204
|
36,319,626
|
soc knockdown suppress metastasi hepatocellular carcinoma amelior hif depend mitochondri damag pringl maneuv pm wide use hepatocellular carcinoma hcc resect howev inevit lead ischemia hypoxia promot tumor metastasi studi immunohistochem stain specimen hcc patient reveal long time pm signific affect prognosi patient high express suppressor cytokin signal soc affect prognosi patient low express soc tcga databas show patient high express soc higher hypoxia score prove soc could promot express hypoxia induc factor subunit alpha hif protein clinic tissu sampl cell experi lung metastas subcutan tumorigenesi experi use cocl construct hypoxia model confirm soc knockdown resist hypoxia induc mitochondri damag inhibit express hif therebi inhibit invas migrat hcc cell immunofluoresc electron microscopi migrat invas experi perform rescu experi use ly rapamycin confirm knockdown soc inhibit hcc cell invas migrat inhibit pikaktmtorhif signal axi import obtain consist conclus clinic cellular anim studi hypoxia induc invas migrat abil soc inhibit hcc weaker normal hcc conclus identifi novel role soc regul hif depend mitochondri damag metastasi pikaktmtor pathway develop soc specif inhibitor indirect inhibitor hif might effect control pm induc tumor micrometastas hcc resect
|
D006528;D008113
|
T191
|
36,319,625
|
situ generat micromet size tumor cell deriv vesicl autolog cancer vaccin boost system immun respons cancer vaccin promot tumor specif immunostimul one import immunotherapeut strategi hold tremend potenti cancer treatmentprevent prepar seri nanoparticl compos doxorubicin tyrosin kinas inhibitor load hyaluron acid coat dendrit polym term hddt nanoparticl find hddt nanoparticl convert various cancer cell micromet size vesicl term hmvs cell hmv convers effici confirm two tumor bear mous model nanoparticl restrain tumor growth induc robust immunogen cell death convert primari tumor antigen depot produc hmvs situ serv person vaccin cancer immunotherapi furthermor hddt heal mice show strong immun memori effect hddt treatment realiz long term protect tumor rechalleng collect present work provid general strategi prepar tumor associ antigen contain vesicl develop person cancer vaccin
|
D019496;D053758;D009369
|
T129;T121;T116;T073;T191
|
36,319,624
|
downregul mettl improv postmenopaus osteoporosi via igfbp depend posttranscript silenc smad osteoporosi op tend occur postmenopaus women make prone fractur n methyladenosin methyl play crucial role op herein aim explor effect mettl osteogenesi under mechan osteogen differenti assess osteoblast marker express cell prolifer alp activ miner detect qrt pcr cck edu assay alp stain assay ar stain assay respect osteoporosi evalu ovx mice use qrt pcr microcomput tomographi h e stain assay level mettl smad measur use qrt pcr western blot interact assess use rip luciferas report assay methyl analyz use rip assay result indic mettl smad level downregul patient op ovx mice upregul osteogen bmscs knockdown mettl suppress osteogenesi bmscs reduc bone mass ovx mice moreov silenc mettl posit relat smad inhibit modif smad suppress stabil igfbp identifi methyl reader knockdown revers upregul induc smad overexpress smad revers suppress osteogen differenti induc mettl knockdown conclus interfer mettl inhibit osteogen differenti bsmcs modif smad igfbp manner suggest mettl might novel approach improv osteoporosi
|
D059630;D035683;D010024;D015663
|
T123;T047;T025;T114
|
36,319,621
|
tiger shark support character world largest seagrass ecosystem seagrass conserv critic mitig climat chang due larg stock carbon sequest seafloor howev effect conserv potenti provid natur base solut climat chang hinder major uncertainti regard seagrass extent distribut describ character world largest seagrass ecosystem locat bahama integr exist spatial estim updat empir remot sens product perform extens ground truth seafloor diver survey across remot sens tile also leverag seafloor assess movement data obtain instrument equip tiger shark strong fidel seagrass ecosystem augment valid predict report consensus area least km km seagrass habitat across bahama bank sediment core analysi store organ carbon confirm global relev blue carbon stock ecosystem data tiger shark prove import support map ground truth remot sens estim work provid evid major knowledg gap ocean ecosystem benefit partner marin anim address gap underscor support rapid protect ocean carbon sink
|
D017753;D012754
|
T070;T082;T013
|
36,319,619
|
function eefk eef pathway nac critic express cocain induc psychomotor sensitis condit place prefer recent evid link synapt plastic mrna translat via eukaryot elong factor kinas eefk known substrat eef howev involv eef pathway cocain induc neuroadapt cocain induc behaviour known knock ki mice shrna use global specif reduc eefk express cocain psychomotor sensit condit place prefer use evalu behaviour outcom chang eef phosphoryl determin western blot analys effect observ ampanmda receptor current ratio ventral tegment area h cocain inject eefk ki mice compar wt howev develop express cocain psychomotor sensit decreas ki mice phosphoryl eef decreas one day psychomotor sensit return baselin seven day nucleus accumben nac wt mice eefk ki mice howev one day follow cocain challeng phosphoryl eef decreas wt ki mice import specif target eefk express shrna nac decreas cocain condit place prefer result suggest eef pathway play role cocain induc locomotor sensit condit place prefer
|
D054736;D003042
|
T121;T116;T109;T131;T126
|
36,319,618
|
gut microbiom dysbiosi antibiot treat covid patient associ microbi transloc bacteremia although microbi popul gut microbiom associ covid sever causal impact patient health establish provid evid gut microbiom dysbiosi associ transloc bacteria blood covid caus life threaten secondari infect first demonstr sar cov infect induc gut microbiom dysbiosi mice correl alter paneth cell goblet cell marker barrier permeabl sampl collect covid patient two differ clinic site also reveal substanti gut microbiom dysbiosi includ bloom opportunist pathogen bacteri genera known includ antimicrobi resist speci analysi blood cultur result test secondari microbi bloodstream infect pair microbiom data indic bacteria may transloc gut system circul covid patient result consist direct role gut microbiom dysbiosi enabl danger secondari infect covid
|
D000069196;D000086382;D060085;D016470
|
T067;T047;T007;T001
|
36,319,601
|
modul myeloid deriv suppressor cell long non code rnas tumor microenviron tumorigenesi myeloid deriv suppressor cell mdscs constitut import compon regul immun respons cancer long non code rnas lncrnas untransl function rna molecul grow evid lncrnas involv modul transcript factor becom complex regulatori network regul immun function activ mdscs immunosuppress tumor microenviron review focus emerg role lncrnas mdscs activ summar lncrnas modul differenti expans immunosuppress function mdscs under mechan hope lncrnas target may prevent growth develop mdscs immunosuppress tumor microenviron
|
D000072737;D062085;D009369
|
T123;T191;T025;T114
|
36,319,511
|
elimin bright induct effect measur motion centr surround suppress contrast perceiv contrast central stimulus supress embed higher contrast surround centr surround suppress contrast local bright induct effect two stimulus region propos account conflict result relat grate phase differ suppress bright induct effect dissoci use centr surround arrang move grate four experienc observ involv experi utilis two interv forc choic contrast match task stimuli drift sinusoid grate pattern surround contrast differ direct motion orient relat contrast centr grate first phase offset direct surround condit compar direct phase align oppos direct condit reduct suppress phase offset condit suggest reduct bright induct influenc suppress examin surround direct vari phase either fix randomis small chang motion direct centr surround amount bright induct vari sinusoid differ phase introduc direct differ final spatial separ centr surround vari determin reduct suppress bright induct increas spatial distanc found fit exponenti decay function surround suppress produc larger rang influenc find quantifi bright induct suppress effect valid use phase randomis remov effect bright induct evalu surround suppress
|
D015350;D009039
|
T041
|
36,319,462
|
clinic featur prognosi cutan melanoma object analyz clinic featur prognosi patient cutan melanoma method clinic data follow data patient cutan malign melanoma cmm treat tongji hospit tongji medic colleg huazhong univers scienc technolog februari august collect kaplan meier method log rank test use surviv analysi cox proport risk regress model use impact factor analysi result among patient stage stage stage stage acral non acral median surviv time month year surviv rate respect kaplan meier univari surviv analysi show karnofski perform status score tumor stage primari site vascular infiltr ki braf lactat dehydrogenas ldh surgic treatment relat prognosi patient p median overal surviv os time patient receiv interferon treatment month better month patient receiv interferon treatment differ statist signific p among stage patient median os time patient receiv interferon therapi month better month patient receiv interferon therapi p among stage patient year surviv rate acral patient year surviv rate non acral patient prognosi patient stage acral type better non acral type p median surviv time stage patient acral type month better month non acral type differ statist signific p median surviv time acral type non acral type month month respect p cox multivari analysi show tumor stage preoper ldh level independ prognost risk factor cutan melanoma conclus interferon treatment improv prognosi patient stage stage acral type patient better prognosi non acral type patient tumor stage preoper ldh level independ prognost risk factor cutan melanoma
|
D008545;D012878
|
T191
|
36,319,461
|
influenc lung metastasi prognosi previous untreat gestat trophoblast neoplasia patient object investig impact lung metastas prognosi patient gestat trophoblast neoplasia gtn method patient intern feder gynaecolog obstetr figo stage gtn receiv primari chemotherapi peke union medic colleg hospit juli decemb retrospect analyz divid group lung metastasi group without lung metastasi baselin characterist treatment outcom two group compar optim cut valu diamet largest lung nodul associ recurr identifi receiv oper characterist roc curv logist regress analys perform identifi risk factor prognosi surviv analysi perform kaplan meier method log rank test result gtn patient enrol lung metastas without lung metastas pretreat human chorion gonadotrophin median iul iul vs iul iul p figo score median vs p signific higher patient lung metastas without lung metastas patient figo score emerg resist vs p median number chemotherapi cours achiev complet remiss vs p signific higher patient lung metastas patient figo score signific differ found treatment outcom two group p among patient lung metastas roc curv show sensit specif respect predict recurr length largest lung nodul cm area curv auc ci p multivari logist regress analysi suggest signific higher recurr rate largest lung nodul cm ci p year diseas free surviv rate signific lower patient largest lung nodul cm patient nodul cm vs p conclus lung metastasi associ increas first line chemotherapi resist patient figo score diamet largest lung metastat nodul cm effect factor predict recurr
|
D031901;D008175
|
T047;T191
|
36,319,460
|
relationship metastasi para aortic lymph node cervic cancer patholog featur object investig incid relat risk factor para aortic lymph node metastasi cervic cancer method patholog data patient cervic cancer underw radic hysterectomi pelvic para aortic lymph node dissect retrospect analyz relat postop patholog paramet para aortic lymph node metastasi statist analyz result among patient cervic cancer para aortic lymph node metastasi univari analysi show tumor size depth muscular invas vessel invas uterin bodi invas vagin invas parametri invas posit surgic margin ovari metastasi fallopian tube metastasi pelvic lymph node metastasi common iliac lymph node metastasi associ para aortic lymph node metastasi multivari logist regress analysi show diamet primari tumor cm parametri invas pelvic lymph node metastasi common iliac lymph node metastasi independ risk factor para aortic lymph node metastasi conclus diamet primari tumor cm parametri invas pelvic lymph node metastasi common iliac lymph node metastasi independ risk factor para aortic lymph node metastasi cervic cancer tumor size common iliac lymph node status fulli evalu initi oper addit assess postop pelvic lymph node status parametri status help reduc rate misdiagnosi miss diagnosi provid basi individu treatment prognost judgment
|
D002583
|
T191
|
36,319,459
|
long term outcom failur pattern definit radiotherapi cervic esophag carcinoma object evalu long term outcom failur pattern prognost factor definit radiotherapi patient cervic esophag carcinoma cec method retrospect review clinic data cec patient treat definit radiotherapi cancer hospit chines academi medic scienc januari decemb median radiat dose gy gy patient receiv concurr chemotherapi kaplan meier method use calcul surviv rate log rank test use surviv comparison univari prognost analysi cox model use multivari prognost analysi result median follow time month median surviv time year overal surviv os month median year progress free surviv month year locoregion recurr free surviv year distant metastas free surviv multivari analysi show eqd gy independ prognost indic os p median surviv time year os rate signific improv patient receiv eqd gy receiv gy month vs month vs p total patient develop tumor progress patient develop local region recurr distant metastas respect eleven patient underw salvag surgeri laryng preserv rate entir group conclus definit radiotherapi effect treatment cervic esophag carcinoma advantag larynx preserv local recurr major failur pattern eqd gy associ improv overal surviv
|
D004938;D002277
|
T191
|
36,319,458
|
relationship dynam chang psycholog distress qualiti life chines earli breast cancer patient object explor dynam chang distress thermomet score relationship psycholog distress qualiti life chines earli breast cancer patient chemotherapi method prospect studi enrol chines postop earli breast cancer patient march decemb psycholog distress qualiti life qol patient assess use psycholog distress manag screen tool patient qualiti life scale logist regress model use analyz influenc factor psycholog distress degre correl distress thermomet dt score chang qualiti life analyz pearson correl analysi result total valid case analyz chemotherapi case dt score point cycl chemotherapi case dt score point thirti four patient dt score point chemotherapi dt score chemotherapi lower chemotherapi cycl chemotherapi univari analysi show incom level patholog stage still signific relat detect dt score point chemotherapi p chang dt score chemotherapi negat correl chang qualiti life r p conclus detect rate psycholog distress patient earli breast cancer chemotherapi show decreas trend incom level tumor stage signific factor affect psycholog distress patient signific correl psycholog distress qualiti life chemotherapi pay attent evalu monitor state psycholog distress patient chemotherapi
|
D001943;D000079225;D009369
|
T191;T048
|
36,319,457
|
preval risk factor coronari arteri calcif lung cancer screen low dose ct object investig preval risk factor coronari arteri calcif cac lung cancer screen low dose comput tomographi ldct method total asymptomat subject male femal underw ldct lung cancer screen recruit cancer hospit chines academi medic scienc visual score method use assess coronari arteri calcif score test independ test use compar differ cac posit rate among differ group multivari logist regress use analyz risk factor associ cac studi result asymptomat subject cac occur case posit rate mild moder sever calcif account respect gender age bmi educ level occup smoke histori diabet hypertens hyperlipidemia statist signific differ cac posit rate among group multivari logist regress analysi show gender age diabet hypertens hyperlipidemia smoke histori risk factor cac age diabet hypertens smoke histori statist signific risk factor mild moder cac group total coronari arteri cac posit case calcif cac posit rate left anterior descend highest case singl vessel calcif case multipl vessel calcif conclus ldct use one stop earli detect lung cancer coronari atherosclerosi gender age diabet hypertens hyperlipidemia smoke relat risk factor coronari atherosclerosi
|
D003324;D008175;D061205;D006973;D006949
|
T033;T047;T191
|
36,319,456
|
express regulatori role ultraconserv long non code rna uc lung cancer object investig effect molecular mechan ultra conserv long non code rna uc lung cancer method lung cancer tissu adjac normal tissu obtain patient lung cancer diagnos lung cancer underw surgeri general hospit southern theater command peopl liber armi real time fluoresc quantit polymeras chain reaction qrt pcr use detect uc relat express normal human bronchial epitheli cell hbe lung cancer cell line pair lung cancer tissu uc sirna transfect lung cancer cell interfer express uc qrt pcr use verifi interfer effect cck method clone format experi use detect cell prolifer abil flow cytometri use detect apoptosi cell cycl chang h cell transfect uc sirna inject subcutan right side balbc nude mice construct tumor bear model explor role uc tumor growth western blot qrt pcr method use detect protein mrna express p result relat express level uc lung cancer cell line h h h hbe signific higher hbe cell p uc rna express level lung cancer tissu signific higher adjac normal tissu p addit increas lncrna uc express signific associ big tumor size lymph node metastasi advanc tnm stage p transfect uc sirna express uc h hbe cell reduc p cell prolifer capac reduc hour hour p transfect uc sirna g g phase cell ratio h sirna group higher h control group h sirna nc group p phase cell ratio h sirna group lower h control group h sirna nc group p apoptosi rate h sirna group higher h control group h sirna nc group p coloni format rate h sirna group lower h control group h sirna nc group p result nude mice tumor format experi show tumor volum h sirna group signific lower h control group h negat control group p averag tumor weight h sirna group signific lower h control group h negat control group p tumor cell growth marker ki h sirna group show weak posit ki h control group h negat control group show posit result qrt pcr analysi show mrna express level p h sirna group higher h control group p h sirna nc group p result western blot analysi also show express p protein level h sirna group increas conclus express ultraconserv long non code rna uc elev lung cancer cell line lung cancer tissu silenc express ultraconserv long noncod rna uc inhibit tumor growth block uc express may potenti therapeut target lung cancer
|
D062085;D008175
|
T123;T191;T114
|
36,319,455
|
epidem characterist esophag cancer mortal qidong object describ epidem characterist esophag cancer mortal qidong provid baselin make control measur strategi prevent method cancer registri data collect analyz mortal oesophagus cancer qidong differ sex age time indic statist includ crude mortal rate cr china age standard rate casr world age standard rate wasr year truncat rate year cumul rate cumul risk averag annual percentag chang aapc mortal period mortal birth cohort result total esophag cancer case male femal die year account cancer death crude mortal casr wasr crude mortal signific increas age crude mortal casr wasr respect averag annual percentag chang aapc mortal esophag cancer age group decreas sinc age birth cohort analysi show declin mortal rate age group conclus crude mortal rate esophag cancer increas slight qidong china age standard rate world age standard rate decreas signific howev esophag cancer still one malign tumor affect health resid serious threaten peopl live health situat cancer prevent control still serious qidong
|
D004938
|
T191
|
36,319,454
|
long term trend esophag cancer surviv rate qidong object analyz surviv esophag cancer case qidong jiangsu provinc provid basi prognosi evalu prevent esophag cancer patient method data esophag cancer obtain qidong cancer registr report system follow date end decemb observ surviv rate osr relat surviv rate rsr calcul surv softwar hakulinen likelihood ratio test use statist differ comparison joinpoint regress model use conduct averag annual percentag chang aapc esophag cancer surviv rate arima model use predict trend esophag cancer surviv rate result new case esophag cancer qidong osr esophag cancer year rsr year respect divid period compar year rsr increas rsr trend period statist signific p surviv rate femal esophag cancer slight higher male howev signific differ rsr male femal p osr rsr male femal respect rsr age group year old respect statist signific differ rsr among differ age group p time trend result show overal aapc rsr esophag cancer qidong p rsr uptrend consist among differ gender uptrend greater femal aapc male aapc femal p furthermor rsr esophag cancer age group show upward trend upward trend statist signific year old group aapc p year old group aapc p surviv rate predict esophag cancer show rsr increas conclus overal surviv rate esophag cancer whole popul qidong improv certain extent still larg room improv emphasi continu strengthen earli diagnosi earli treatment esophag cancer
|
D004938
|
T191
|
36,319,453
|
chins expert consensus issu relat protect treatment manag patient solid tumor covid edit new coronavirus still global pandem stage present delta strain omicron strain main circul strain mutant strain stronger infect origin virus content covid pandem social public resourc medic resourc may affect lead medic treatment delay interrupt patient malign tumor base relev research clinic practic home abroad cancer support therapi committe china anti cancer associ cancer clinic chemotherapi committe china anti cancer associ light china nation condit avail resourc vaccin antivir drug formul consensus chines expert issu relat prevent treatment manag patient solid tumor main content includ vaccin cancer patient covid optim medic resourc time restart anti tumor therapi covid infect articl aim provid refer clinic practic
|
D000086382;D009369
|
T047;T191;T067
|
36,319,452
|
expert consensus whole cours manag home medic care patient pancreat cancer china pancreat cancer known king cancer incid mortal pancreat cancer increas year year worldwid prognosi pancreat cancer poor effect exist diagnosi treatment method limit oncologist branch chines medic doctor associ pancreat diseas special committe china intern exchang promot associ medic health care abdomin tumor special committe china medic educ associ conven relev expert put forward use suggest clinic refer nine aspect home manag patient pancreat cancer includ condit communic follow nutrit support cancer pain manag psycholog adjust ascit manag jaundic manag daili food manag aim improv qualiti life prolong surviv time patient pancreat cancer
|
D011788;D010190
|
T078;T191
|
36,319,451
|
chines expert consensus earli diagnosi treatment esophag cancer although incid rate esophag cancer china declin china still high incid countri esophag cancer great region variat recent year five year surviv esophag cancer china improv signific howev due absenc typic symptom earli stage still exist larg esophag cancer diagnost yield gap china develop countri present intern guidelin defin target popul esophag squamous cell carcinoma escc screen explor implement effect esophag cancer screen togeth earli diagnosi earli treatment key reduc mortal improv surviv rate life qualiti endoscop therapi endoscop submucos dissect esd endoscop mucos resect emr radiofrequ ablat rfa use treat earli stage esophag cancer tumor invas deep lymph node metastasi suspect surgeri need meanwhil radiat therapi could also option treatment regular follow surveil requir strategi deal relaps metachron primari cancer earli diagnosi treatment group chines medic associ oncolog branch reach expert consensus screen diagnost protocol esophag cancer endoscop surgic treatment earli esophag cancer precancer lesion well postop monitor adjuv therapi consensus follow evid base medicin domest intern level combin current clinic practic applic experi treatment esophag cancer china base multidisciplinari treatment model use refer clinician
|
D004938;D000077277;D000069916
|
T061;T191
|
36,319,450
|
chines expert consensus immunotherapi advanc non small lung cancer oncogen driver mutat edit non small cell lung cancer nsclc oncogen driver mutat previous deem forbidden territori immunotherapi grow understand impact target drug immun microenviron continu generat clinic evid immunotherapi expect bring new hope nsclc patient oncogen driver mutat expert panel medic oncolog respiratori medicin patholog organ societi cancer precis medicin chines anti cancer associ expert group lung cancer chines medic journal conduct depth discuss current evid immun microenviron clinic studi formul chines expert consensus immunotherapi advanc nsclc oncogen driver mutat combin clinic experi expert consensus aim provid guidanc chines clinician immunotherapi nsclc oncogen driver mutat
|
D008175;D002289
|
T191
|
36,319,449
|
china guidelin pharmaceut care anti tumor antibodi base drug antibodi base drug prepar cell genet engin technolog wide use treatment malign tumor accord structur characterist antibodi base drug current market divid sever categori includ monoclon antibodi drug bispecif antibodi drug antibodi drug conjug june anti tumor antibodi drug approv china sinc pharmaceut characterist vivo efficaci pharmacokinet characterist anti tumor antibodi drug differ tradit small molecul drug pharmaceut care anti tumor antibodi drug clinic applic distinct featur regul pharmaceut care drug promot ration use antibodi drug china guidelin made cancer pharmacist branch chines pharmacist associ guidanc nation cancer center use delphi method expert interview discuss build key problem content guidelin base clinic evid domest pharmaceut manag regul pharmaceut care practic guidelin cover whole process pharmaceut care system includ use drug administr provid scientif basi pharmacist carri pharmaceut care kind drug
|
D010593;D000970
|
T121;T058;T170;T109
|
36,319,434
|
ensembl inequival negat extens strong stretch wormlik chain fluctuat bend stiff mani semiflex polym exhibit fluctuat local bend stiff along contour may due intrins conform chang eg denatur bubbl format doubl strand dna helix coil transit polypeptid revers adsorpt desorpt molecul polym environ eg dna protein interact hybrid oligonucleotid articl analyz tensil elast strong stretch wormlik chain consist n concaten segment segment one two state b differ bend stiff call model revers wormlik chain rwlc model gibb fix forc isotension ensembl obtain analyt express forc extens relat mean fraction b segment show certain condit tension induc crossov most most b rwlc helmholtz fix extens isometr ensembl obtain analyt express summat show finit n mark ensembl inequival remark helmholtz ensembl rwlc exhibit negat extens multipl peak
|
D004247;D011108
|
T123;T122;T104;T114
|
36,319,430
|
detail dynam discret gaussian semiflex chain arbitrari stiff along contour revisit model semiflex gaussian chain propos winkler et al solv dynam discret descript model deriv exact algebra express relev dynam observ mean squar displac individu monom dynam structur factor end end vector relax shear stress relax modulus mathemat express dynam structur factor verifi compar result brownian dynam simul report excel agreement general model linear polym chain arbitrari stiff particular focus case linear polym stiff chang linear one end chain studi dynam function previous present discuss differ approach check whether polym constant heterogen stiff along contour final provid express lagrangian multipli gaussian chain variabl stiff bond length well chain torsion like interact overal work present new insight well known model semiflex chain provid tool exploit explor much broader class polym compar predict model simul coars grain semiflex polym
|
D056004;D011108
|
T104;T066;T122;T044
|
36,319,425
|
multiconfigur short rang densiti function theori nuclear magnet reson shield constant gaug includ atom orbit paper present theori implement nuclear magnet reson shield constant gaug includ atom orbit hybrid multiconfigur short rang densiti function theori model special case implement also includ hartre fock srdft hf srdft choos complet activ space cas wave function multiconfigur parameter wave function investig well cas srdft reproduc experiment trend nuclear shield constant compar dft complet activ space self consist field casscf calcul nucleobas adenin thymin show cas srdft perform averag best test method much better casscf margin better hf srdft perform compar regular dft similar function contain exact exchang use general find inclus exact exchang import accur descript shield constant case exact exchang includ observ hf cas srdft often outperform regular dft calcul transit metal nuclei organometal compound signific static correl cas srdft method outperform casscf compar experiment shield constant chang hf srdft substanti conclus static correl pose metal complex seem captur cas srdft promis sinc type correl well describ regular dft
|
D011789;D009942
|
T170;T109
|
36,319,420
|
interatom forc neural network base variat quantum mont carlo accur ab initio calcul fundament import physic chemistri biolog materi scienc wit rapid develop last coupl year help machin learn comput techniqu neural network recent effort appli neural network ab initio calcul focus energi system studi take step forward look interatom forc obtain neural network wavefunct method implement test sever common use forc estim variat quantum mont carlo vmc result show neural network ansatz improv calcul interatom forc upon tradit vmc relationship forc error qualiti neural network contribut differ forc term comput cost term also discuss provid guidelin futur applic work demonstr promis appli neural network wavefunct method simul structuresdynam moleculesmateri provid train data develop accur forc field
|
D011789;D016571
|
T170
|
36,319,416
|
multiparticl orient correl respons nonlinear dielectr effect analysi temperatur depend measur glycerol nonlinear dielectr effect nde tradit view origin satur respons individu dipol strong electr field mean field view mathemat describ langevin satur function predict enhanc dielectr satur lower temperatur contrast recent experi glycerol shown sharp increas nde increas temperatur formal present split nde sum term repres binari correl dipolar orient term refer three four particl orient correl analysi experiment data show contribut three four particl correl strong increas elev temperatur mean field pictur dielectr satur origin nde inconsist observ posit nde increment field depend dielectr constant predict low concentr solut polar molecul nonpolar solvent depend nde concentr polar compon polynomi
|
D005990;D000465
|
T123;T121;T170;T109
|
36,319,415
|
frenkel exciton photodynam self assembl monolay azobiphenyl perform comput simul photodynam self assembl monolay sam azobenzen deriv azobiphenyl abpt gold surfac exciton approach adopt semiempir framework allow us consid explicit electron degre freedom azobenzen chromophor surfac hop scheme use nonadiabat molecular dynam simul accord result tran abpt sam excit energi transfer differ chromophor fast manifold occur n state consequ excit transfer play import role quench azobenzen photoisomer sam experiment observ reproduc calcul instead attribut steric effect
|
D001391;D056004
|
T066;T130;T044;T109
|
36,319,405
|
polyodenet deriv mass action rate equat incomplet transient kinet data kinet reaction network follow mass action rate law describ system ordinari differenti equat ode polynomi right hand side howev challeng deriv kinet differenti equat transient kinet data without know reaction network especi data incomplet due experiment limit introduc program polyodenet toward goal base machin learn method neural ode polyodenet defin generat model predict concentr arbitrari time possibl includ unmeasur intermedi speci kinet equat import implement various measur appli physic constraint chemic knowledg train regular solut space use simpl catalyt reaction model demonstr polyodenet predict reaction profil unknown speci even reveal hidden part reaction mechan
|
D000465
|
T170
|
36,319,360
|
design optim two degre freedom parallel four pure slide four parallel quadrilater pair precis posit platform aim complex structur small output displac low posit accuraci two degre freedom dof precis posit platform theoret analys experiment test carri platform characterist compact structur larg output stroke high posit accuraci first optim structur paramet posit platform model method improv model accuraci compliant mechan posit platform propos static model posit platform base euler bernoulli beam theori sixth order complianc matrix method establish accuraci model verifi simul addit singl object genet optim algorithm use optim structur size paramet posit platform optim solut set structur size paramet posit platform obtain take displac amplif rate posit platform optim target final accord theoret simul analysi optim result experiment prototyp fabric seri experiment test carri work stroke displac magnif output stiff experiment result show displac magnif posit platform reach posit stroke displac resolut x axi axi nm respect posit platform design paper meet requir larg output stroke high posit accuraci
|
D020521
|
T047
|
36,319,346
|
onlin charg measur petawatt laser driven ion acceler laser driven ion beam gain consider attent potenti use multidisciplinari research technolog preclin studi radiobiolog effect establish prospect use laser driven ion beam radiotherapi particular research benefici effect ultrahigh instantan dose rate enabl high ion bunch charg uniqu short bunch length present laser driven ion beam studi requir reliabl onlin dosimetri method monitor bunch charg everi laser shot ensur prescrib dose accur appli biolog sampl paper present first success use integr current transform ict laser driven ion acceler noninvas diagnost measur charg acceler ion bunch enabl onlin estim appli dose radiobiolog experi facilit ion beam tune particular optim laser ion sourc align proton transport beamlin present ict implement correl diagnost radiochrom film thomson parabola spectromet scintil
|
D010315;D007834
|
T074;T073
|
36,319,327
|
adapt capon beamform lensless electron cyclotron emiss imag high spatial resolut electron cyclotron emiss ece imag diagnost incorpor lensless approach develop measur involv activ spatial select direct arriv estim capon method adapt array analysi propos improv spatial resolut two dimension ece imag techniqu broadband nois sourc emiss use simul ece verifi practic effect capon method ece imag multipl nois sourc emiss posit proper estim high spatial resolut use capon method
|
D004583;D017357
|
T081;T196;T074;T073
|
36,319,314
|
recent advanc microreson support instrument electron paramagnet reson spectroscopi electron paramagnet reson epr spectroscopi character magnet properti paramagnet materi atom molecular level reson enabl technolog epr spectroscopi microreson miniatur version reson advanc induct detect epr spectroscopi mass limit sampl provid perspect benefit challeng associ microreson use epr spectroscopi begin classifi applic space microreson present conceptu foundat analysi reson sensit summar previous work provid insight design fabric microreson well detail requir challeng aris incorpor microreson epr spectromet system final provid perspect current challeng prospect fruit direct
|
D008280
|
T090
|
36,319,309
|
general weight permut entropi novel heurist approach propos time seri data analysi dub general weight permut entropi amalgam general beyond origin scope two well establish data analysi method permut entropi weight permut entropi method introduc scale paramet discern disord complex ordin pattern small larg fluctuat use scale paramet complex entropi causal plane general complex entropi scale causal box simul conduct synthet seri generat stochast chaotic random process well real world data shown produc uniqu signatur three dimension represent
|
D019277
|
T067
|
36,319,307
|
scale free avalanch dynam possibl generat random jump among mani stabl state larg amount research use scale free statist neuron avalanch signatur critic neural system bear critic instanc work touboul destexh demonstr non critic system could also display scale free dynam pass rigor statist analys paper show fulli connect stochast neural network may also generat scale free dynam simpli jump among mani stabl state
|
D008959;D009474
|
T170;T025
|
36,319,306
|
network spread among area dynam complex network model approach outbreak covid great loss damag brought human societi make studi epidem spread becom signific topic nowaday analyz spread infecti diseas among differ area eg communiti citi countri construct network base epidem model network coupl whose node denot area edg repres popul migrat two area node follow dynam describ epidem spread among individu area node also interact node indic spread among differ area give mathemat proof deduc model stabl solut despit network structur propos peak infect ratio pir properti infecti diseas certain area independ network structur find increas popul mobil diseas infecti caus higher peak infect popul differ simul furthermor appli model real world data covid proper adjust paramet model distribut peak infect ratio differ area well fit
|
D000086382;D058872;D003141
|
T047;T067
|
36,319,304
|
structur infer flock system base trajectori interact swarm individu affect dynam behavior swarm difficult obtain direct outsid observ therefor problem focus infer structur interact swarm individu behavior trajectori similar infer problem exist network scienc name network reconstruct network infer fundament problem pervad research complex system paper new method call motion trajectori similar develop infer direct interact motion state individu swarm construct correl combin similar motion trajectori cross section time seri individu high similar motion state like interact experi flock system demonstr method produc reliabl interact infer outperform tradit network infer method withstand high level nois time delay introduc flock model well paramet variat flock system achiev robust reconstruct propos method provid new perspect infer interact structur swarm help us explor mechan collect movement swarm pave way develop flock model quantifi predict
|
D009038
|
T070
|
36,319,303
|
identifi causal driver deriv govern equat nonlinear complex system identifi describ dynam complex system central challeng various area scienc physic financ climatolog machin learn algorithm increas overtak tradit approach inner work thus driver causal remain elus paper analyz causal structur chaotic system use fourier transform surrog three differ infer techniqu confirm granger causal exclus abl detect linear causal transfer entropi converg cross map indic causal determin signific extent nonlinear properti lorenz halvorsen system find contribut independ strength nonlinear coupl furthermor show simpl rational calibr algorithm suffici extract govern equat direct causal structur data final illustr applic framework real world dynam system use financi data covid outbreak turn pandem trigger fundament ruptur world economi reflect causal structur result equat
|
D017711;D000086382
|
T077;T047;T170;T067
|
36,319,301
|
collect excit high dilut random network oscil report collect excit event high dilut random network non excit node excit aris thank self sustain local adapt mechan drive system slow timescal across hysteret phase transit involv state differ degre synchron phenomena investig kuramoto model bimod distribut natur frequenc kuramoto model inertia unimod frequenc distribut consid global partial stimul protocol character system respons differ level dilut compar result obtain fulli coupl case show collect phenomena remark robust network dilut
|
D003198
|
T066
|
36,319,300
|
model free predict multist use echo state network field complex dynam multist attractor gain signific attent due unpredict occurr extrem sensit initi condit co exist attractor abund divers system rang climat financ ecolog social system articl investig data driven approach infer differ dynam multist system use echo state network start paramet awar reservoir predict divers dynam differ paramet valu interest machin abl reproduc dynam almost perfect even distant paramet lie consider far paramet valu relat train dynam continu predict whole bifurc diagram signific accuraci well extend studi explor various dynam multist attractor unknown paramet valu train machin dynam one attractor paramet p captur dynam co exist attractor new paramet valu p p continu simul multipl set initi condit identifi basin differ attractor general result appli scheme two distinct multist system
|
D003198
|
T066
|
36,319,297
|
boundari dynam non smooth memrist hindmarsh rose neuron system paper complex dynam non smooth hindmarsh rose hr neuron system local activ memristor discuss theori discontinu dynam system six map structur two boundari employ illustr various switch behavior system analyt condit hr system switch motion passabl motion graze motion investig extrem multist improv hr neuron reveal switch bifurc paramet map attract basin fire activ various mode hr system coexist various fire behavior observ chang initi valu furthermor hardwar circuit implement hr system establish valid numer result
|
D008959;D009474
|
T170;T025
|
36,319,294
|
phase frustrat induc remot synchron remot synchron rs may take import role brain function studi attract much attent recent year far studi rs focus stuart landau oscil mean field coupl howev realist case may complic coupl behavior brain network make studi rs substanti progress toward realist situat present model rs phase frustrat show rs induc system rs exist phase frustrat numer simul stuart landau kuramoto oscil find optim rang rs depend match phase frustrat hub leaf node fix relationship match figur non optim rang rs find rs exist linear band phase frustrat hub leaf node brief theoret analysi provid explain result
|
D008962;D005639
|
T062;T170;T041
|
36,319,293
|
birth strang nonchaot attractor piecewis linear oscil nonsmooth system wide encount engin field abund dynam phenomena includ result complex dynam system quasiperiod forc excit work consid quasiperiod forc piecewis linear oscil show strang nonchaot attractor snas exist nonsmooth system generat evolut mechan snas discuss torus doubl fractal bubbl intermitt rout snas identifi strang properti snas character aid phase sensit function singular continu spectrum ration frequenc approxim path partial fourier sum state variabl complex plane nonchaot properti snas verifi method maximum lyapunov expon power spectrum
|
D017711;D017709
|
T077;T170
|
36,319,291
|
forecast macroscop dynam adapt kuramoto network use reservoir comput forecast system behavior essenti task encount complex system theori machin learn offer supervis algorithm eg recurr neural network reservoir comput predict behavior model system whose state consist multidimension time seri real life often limit inform behavior complex system brightest exampl brain neural network describ electroencephalogram forecast behavior system challeng task provid potenti real life applic train reservoir comput predict macroscop signal produc network phase oscil lyapunov analysi reveal chaotic natur signal reservoir comput fail forecast augment featur space use takken theorem improv qualiti forecast rc achiev best predict score number signal coincid embed dimens estim via nearest fals neighbor method found short time predict requir larg number featur long time predict util limit number featur result refer bias varianc trade import concept machin learn
|
D016571;D000069550
|
T170;T066
|
36,319,290
|
physic captur data base method el nio predict averag everi four year tropic pacif warm consider event call el nio lead weather disrupt mani region earth recent machin learn approach el nio predict particular convolut neural network cnns shown surpris high skill relat long lead time attempt understand high skill use data distort physic simul intermedi complex zebiak cane model determin aspect el nio physic repres specif cnn base classif method find cnn adequ correct distort ocean adjust process machin learn method far troubl deal distort upwel feedback strength
|
D059000;D014887
|
T070
|
36,319,289
|
combin social reward punish conduc cooper heterogen social relat individu behavior social relat influenc howev understand under mechan remain challeng social norm control human behavior individu manag interperson relationship reward punish common use measur simul weak prison dilemma finit popul find neither simpl reward measur pure punish mechan extens promot cooper instead combin appropri punish reward mechan promot cooper prosper regardless larg small temptat defect addit combin spontan produc inhomogen social relat individu influenc support continu exist cooper behavior final explain cooper establish sustain exist combin investig social relat differ moment small system result demonstr dispens reward punish imparti societi essenti social harmoni
|
D011678;D005716
|
T078;T170
|
36,319,287
|
find influenti edg multilay network perspect multilay diffus model popular social network analysi inform diffus model wide rang applic viral market publish predict social recommend emerg multiplex social network great enrich daili life meanwhil identifi influenti edg remain signific challeng key problem lie edg node heterogen differ layer network solv problem first develop general inform diffus model base adjac tensor multiplex network show n mode singular valu control level inform diffus explain suppress inform diffus edg delet effici edg eigenvector central propos identifi influenc heterogen edg numer result synthet network real world multiplex network show propos strategi outperform exist edg central measur devis experiment strategi demonstr influenti heterogen edg success identifi consid network layer central delet top edg signific reduc diffus rang inform across multiplex network
|
D060756
|
T098;T054
|
36,319,286
|
hopf bifurc model term two time delay delay depend paramet base theori cross curv three layer prey predat model two time delay one delay depend paramet establish paper begin paper calcul condit popul model maintain quantiti stabl hopf bifurc stabl interv cross curv type direct cross curv obtain use cross curv method compos threshold valu dynam behavior chang two time delay plane real data forag grass ochotona curzonia buteo hemilasius food chain use conduct empir studi model feasibl region cross curv open end model cross curv plane truncat indic model threshold distribut dynam behavior chang regular curv made sever curv simul use time delay valu cross curv show model produc differ dynam behavior stabil bifurc chao depend time delay valu side curv critic valu dynam behavior chang time delay valu cross curv empir studi show increas ochotona curzonia environment capac easili caus hopf bifurc system time number popul plateau ecosystem constant fluctuat ochotona curzonia vulner extinct
|
D017753;D007793
|
T070;T082;T015
|
36,319,285
|
quantit method determin student workload empir studi base digit platform present quantit studi onlin cours develop covid sanitari emerg chile reconstruct teach learn process consid activ log digit platform order answer question student studi result analysi evid complex adapt charact academ environ exhibit regular similar found financi market eg distribut daili time devot learn activ follow pattern like pareto zipf law empir result illustr relev econom notion understand teach learn process ii reliabl quantit method base digit platform conduct experiment studi framework introduc present work seri indic character perform professor student follow cours learn progress cross inform result assess context learn rate appear key statist descriptor alloc student workload
|
D016526;D000086382
|
T081;T047;T067
|
36,319,283
|
quantit method determin student workload ii statist model microcurricular perform indic previous observ student workload follow invers relat learn rate applic kinemat notion speed contextu learn process motiv find propos quantit estim learn rate use differ sourc inform histor record final grade given cours accord empir data analyz similar studi distribut function final grade exhibit regular pattern gaussian behavior approv region homogen distribut fail one fact combin incid student elimin desert rule introduc two simpl agent base model analysi complement revisit perform indic typic employ character student promot progress discuss perform indic character learn advanc student group learn rate learn curv compar result mont carlo simul empir data observ good agreement behavior perform indic deriv sourc analysi suggest adapt method readjust student workload number academ credit consid group learn rate follow period resembl readjust price good servic correspond evolut suppli demand
|
D016526;D007858
|
T081;T062;T041;T061
|
36,319,281
|
communiti format wealth mediat thermodynam strategi evolut studi dynam system defin repeat game lattic player keep track gross payoff time bank strategi updat govern boltzmann distribut depend neighborhood bank valu associ strategi relat temperatur scale defin random fluctuat player higher bank valu thus less like chang strategi player lower bank valu parameter rock paper scissor game deriv condit communiti given strategi form either fix drift boundari show effect temperatur increas under system identifi surpris properti model numer simul
|
D005716
|
T170
|
36,319,279
|
qualit chang bifurc structur soft vs hard impact model vibro impact energi harvest vibro impact phenomena engin system consid advers effect set intrins part mechan other energi harvest vibro impact compon often intent introduc increas power output system bandwidth impact treat hard instantan impact soft compliant materi sinc type model exhibit complex dynam comparison non trivial develop soft impact model vibro impact energi harvest calibr relev hard impact model larg stiff systemat compar differ phenomena dynam various compliant regim numer result use two differ parametr analys consid bifurc diagram term devic size extern forc paramet vari natur frequenc membran form impact boundari observ shift bifurc structur promot period orbit increas soft paramet often generat higher power output also introduc paramet sensit increas soft complementari analyt result reveal unstabl period orbit co exist behavior potenti miss comput method influenc bifurc structur turn energi output non dimension formul highlight signific ratio extern natur frequenc delin soft hard impact scenario parametr soft impact model exhibit new symmetri break bifurc relat key quantiti character soft impact dynam effect restitut coeffici impact phase contact time interv captur hard impact model
|
D055585
|
T070
|
36,319,278
|
multist evolut chimera state network type ii morri lecar neuron asymmetr nonloc inhibitori connect format synchron activ pattern essenti properti neuron network central interest synchron theori chimera state synchron asynchron activ neuron co exist singl network particular poignant exampl pattern whose dynam multist may underli brain function cognit task howev dynam mechan coher state format spike neuron network well way control state remain unclear paper take step direct consid evolut chimera state network class ii excit morri lecar neuron asymmetr nonloc inhibitori connect use adapt coher measur abl partit network paramet space region various collect behavior antiphas synchron cluster travel wave differ type chimera state well spike death regim shown multist various regim track evolut chimera state function chang key network paramet found transit various type chimera state find network demonstr long transient lead quasi persist activ pattern border region hint near critic behavior
|
D009474
|
T025
|
36,319,277
|
virial like thermodynam uncertainti relat tight bind regim present methodolog approxim entropi product brownian motion tilt period potenti approxim stem well known thermodynam uncertainti relat appli virial like expans provid tighter lower limit sole term drift veloc diffus approach present systemat analyz tight bind regim also provid relat simpl rule valid use tight bind approach base drift diffus relat rather energi barrier forc also discuss implic result outsid tight bind regim
|
D035501
|
T033
|
36,319,276
|
cooper evolut opinion format complex social environ cooper signific aspect daili activ human anim popul involv process agent make decis base part idea belief cooper import communic evolutionari game overst paper offer co evolutionari game model communic network includ express privat opinion present theoret analysi scenario character differ paramet elucid relationship agent opinion format process decis make process final run simul propos model surpris discov wherea communic increas cooper erd rnyi random network barabsi albert scale free network meanwhil discov simul result averag privat opinion simplifi valu within chang direct percentag cooper furthermor discov deceiv conceal true privat opinion may extent foster format collabor human popul goe common sens
|
D001290;D012931
|
T078;T055;T068;T041
|
36,319,275
|
control speci densiti structur perturb intransit cycl higher order interact persist biodivers speci challeng proposit ecolog communiti face darwinian select present articl investig beyond pairwis competit interact provid novel perspect understand influenc higher order interact evolut social phenotyp simpl model yield prosper outlook demonstr impact perturb intransit competit higher order interact use mathemat techniqu show alon perturb interact network quick determin coexist equilibrium compet speci instead solv larg system ordinari differenti equat possibl split system multipl feasibl cluster state depend number perturb analysi also reveal ratio unperturb perturb speci invers proport amount employ perturb result suggest nonlinear dynam system interact topolog interplay comprehend speci coexist advers condit particular find signifi less competit two speci increas abund outperform other
|
D008954;D044822
|
T075;T080
|
36,319,270
|
develop valid ascertain dementia ad thai version ascertain dementia ad brief inform base questionnair reliabl distinguish patient neurocognit disord ncd normal cognit object translat ad thai test valid potenti use measur detect patient mild stage major ncd due alzheim diseas major ncd ad
|
D003704;D060825;D000544
|
T047;T048
|
36,319,269
|
cognit assess time pandem mandatori surgic face mask usag affect cognit test perform older adult import disadvantag surgic mask usag avers affect communic studi aim evalu possibl effect face mask cognit test perform older adult
|
D060825;D000544
|
T047;T048
|
36,319,268
|
risk factor depress among older adult live alon shanghai china rapid popul age increas number older adult live alon import phenomena older adult prone depress studi aim investig depress older adult live alon shanghai risk factor
|
D011788;D000091502
|
T078;T033;T082;T080
|
36,319,267
|
feasibl usabl non immers virtual realiti tele cognit app cognit rehabilit patient affect parkinson diseas cognit impair one common non motor featur parkinson diseas pd aim present studi evalu feasibl acceptabilityus protocol use non immers virtual realiti tele cognit app perform remot sampl italian patient pd
|
D010300;D063731;D000076142
|
T047;T170;T066
|
36,319,266
|
new educ tool neuropsycholog test rater dementia field delphi studi neuropsycholog test primari endpoint clinic research field dementia make essenti rater accur calcul test data extens assess howev mani rater lack adequ skill complet neuropsycholog test suffici confid therefor develop examin util checklist manual tool educ rater basic behaviour conduct comprehens neuropsycholog evalu field dementia
|
D057189;D003704
|
T170;T048
|
36,319,265
|
mentor student research case studi evalu benefit best practic effort mentor undergradu research requir time energi resourc yield signific benefit review educ research undergradu research present follow case studi technic educ principl literatur implement practic new underwat acoust lab case studi involv student join lab first three year result highlight import sever key factor mentor implement improv student research experi order meet steep learn curv new student face faculti mentor establish cultur research ie well establish norm expect practic associ part research group clear expect open communic student led peer mentorship support care select design resourc ie scaffold paper seek share educ research resourc acoust communiti provid case studi review specif applic key principl acoust laboratori set
|
D008611;D013334
|
T065;T081;T098
|
36,319,263
|
frequenc depend ultrason power reflect water tissu interfac human cancel bone vitro numer studi perform vitro ultrason measur cancel bone water develop techniqu ultrason bone assess cancel bone high porous medium ultrason reflect water bone interfac may frequenc depend goal studi investig effect poros frequenc depend reflect power ultrason measur perform water tank room temperatur specimen cancel bone prepar proxim end human femur use singl element broadband transduc center frequenc mhz power spectra puls reflect water specimen interfac correct frequenc respons measur system obtain reflect power decibel r db f suppress random phase cancel effect r db f averag multipl site multipl specimen frequenc depend r db f observ mhz rang frequenc depend moder maximum chang less db entir frequenc rang r db f greatest low poros specimen frequenc averag intens reflect coeffici rang high low poros specimen group respect
|
D014465;D000071556
|
T070;T024
|
36,319,262
|
time seri analysi model relationship psychoacoust paramet urban soundscap spatial sequenc emot chang listen test conduct particip obtain data emot chang respons three type urban soundscap spatial sequenc establish time seri model relationship psychoacoust paramet sequenc chang two dimens emot determin result show psychoacoust paramet explain chang pleasant arous dimens emot respect rough fluctuat highest correl emot chang loud articul index lowest correl emot chang research verifi lag psychoacoust chang soundscap associ perceiv emot first lag psychoacoust paramet emot chang second chang rough loud could caus synchron chang emot paramet could caus delay chang emot final lag emot strong stabl explanatori power emot chang research prove effect time seri analysi technolog establish dynam relationship acoust paramet soundscap sequenc second second perceiv emot provid new data analysi method depth studi soundscap sequenc percept
|
D001307;D000162
|
T070;T041
|
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