Javtor/biomedical-topic-categorization-validation

PMID int64 35.7M 36.4M	Title/Abstract stringlengths 22 8.78k	MeshTerms stringlengths 7 101	SemanticTypes stringlengths 4 64
36,318,360	inhibit kifa suppress replic influenza virus inhibit viral entri influenza virus iav caus sever pandem therefor mani ongo effort identifi novel antivir therapeut strategi includ vaccin antivir drug howev influenza virus continu undergo antigen drift shift result emerg mutat virus turn decreas effici exist vaccin antivir drug control iav infect therefor studi sought identifi altern therapeut strategi target host cell factor rather virus avoid infect mutat virus particular investig role kifa one kinesin superfamili protein replic iav kifa increas viral protein level iav infect cell regul initi entri stage viral infect furthermor kifa inhibitor signific suppress viral replic protect mice morbid mortal therefor find demonstr kifa high involv viral replic process viral propag vitro vivo could thus use target develop novel antivir drug	D009980;D007251	T005;T047
36,318,359	express purif intracrin human fgf studi fgfr depend biolog activ fibroblast growth factor fgf one intracrin fgfs ifgf function within cell unlik canon fgfs fgf remain intracellular play biolog role fgf receptor fgfr independ manner establish express system recombin fgf protein e coli investig whether extracellular administr fgf activ cellular signal human fgf two isoform fgfa fgfb depend presenc nuclear local sequenc nlss n terminus two isoform unstabl prepar fgfa mut substitut three cystein residu nls serin fgfb c c termin truncat introduct mutat nls improv solubl fgf prepar e coli exogen addit fgfb fgfb c balbt increas cell prolifer fgfa mut exert effect fgfb c show higher cell prolifer activ fgfr signal fgfb cell prolifer activ fgfb fgfb c block fgfr inhibitor recombin fgfr confirm fgfr depend extracellular activ fgfb analysi circular dichroism suggest c terminus fgf helic structur may affect interact fgfr result suggest n c terminus recombin fgf involv activ fgfr result provid novel insight function mechan fgf may aid develop use ligand fgfr regul	D004926;D005346	T123;T007;T116
36,318,358	cytoplasm molecular chaperon pseudomona speci pseudomona widespread various environment host nich promot rejuven cellular protein homeostasi must fine tune respons divers stress extrem high low temperatur oxid stress desicc result protein homeostasi imbal molecular chaperon function key compon aid protein fold prevent protein denatur pseudomona ecolog import bacteri genus includ human plant pathogen well growth promot symbiont speci use bioremedi review focus protein qualiti control system particular molecular chaperon ecolog divers speci pseudomona includ opportunist human pathogen pseudomona aeruginosa plant pathogen pseudomona syringa soil speci pseudomona putida psychrophil pseudomona antarctica	D044224;D018832	T123;T007;T116
36,318,352	effect wean feed provis time perform sever behaviour trait post wean lamb aim present studi assess wean time morn even feed provis immedi h delay influenc growth perform express juvenil lamb behaviour immedi age day old forti lamb random assign group e even immedi e even delay morn immedi morn delay lamb especi activ first hour wean howev activ within first h wean main affect circadian rhythm sinc lamb activ day compar night hand effect alfalfa hay provis lamb activ first h observ age day old bodi weight measur isol flight distanc test implement signific differ among lamb bodi weight number jump heart rate assess isol test flight distanc howev number vocal lower th day p e compar e lamb breed also slight affect th day p averag heart rate lamb greater valu karagouniko compar chio lamb conclud discern effect wean feed time observ growth perform display stress induc behaviour compon juvenil lamb till age day old	D034561	T015
36,318,350	influenc bacteri biopolym physic properti experiment limeston block articl describ consolid effect bacteri biopolym synthes biofilm bacteria colon mayan limeston build surfac properti limeston block includ disaggreg hard total color chang laboratori level biopolym evalu produc bacteri isol tmb tmb tmb tmb influenc surfac properti differ level rrna gene sequenc analysi show isol tmb relat psychrobact sp strain marseill p tmb relat agrococcus terreus strain bt isol tmb tmb relat xanthomona citri pv mangiferaeindica strain xc biopolym reduc surfac disaggreg materi compar untreat control reveal peel test follow biopolym b remain biopolym neglig effect cactus biopolym reduc disaggreg higher level hand similar concomit increas surfac hard limeston sampl coat biopolym biopolym b higher biopolym c total color chang treatment threshold valu indic non signific color alter partial chemic character best perform biopolym suggest probabl glycoprotein natur whose constitut acid monosaccharid probabl contribut higher adher limeston surfac contribut surfac stabil harden surfac decreas surfac decohes preliminari find suggest potenti applic bioconsolid studi requir	D002119;D001419	T121;T197;T007
36,318,345	featur select approach identifi potenti plasma metabolit postmenopaus osteoporosi patient postmenopaus women osteoporosi pmop prone fragil fractur osteoporosi associ alter level specif circul metabolit	D015663;D010024	T047
36,318,344	small extracellular vesicl load immunosuppress mirna lead inhibit dendrit cell matur particular condit inhibit immun respons requir prevent tissu damag among condit diseas caus reactiv immun respons autoimmun allerg disord immin organ reject transplant avoid tissu damag drug mediat system immun suppress option come high cost form suscept viral bacteri infect thus induct antigen specif toler prefer extracellular vesicl ev capabl deliv antigen togeth immunosuppress signal may use specif induc antigen specif toler howev natur occur ev heterogen show immunosuppress charact trial engin cell cultur deriv ev increas tolerogen potenti equip immunosuppress mirna mimic small ev sev isol purifi human monocyt thp cell line healthi donor peripher blood mononuclear cell electropor mir mir mimic acquir immunosuppress potenti modifi sev demonstr abil alter major histocompat complex molecul co stimulatori receptor present dendrit cell dcs avoid allogen respons cell produc sev serv also recipi cell contrast treatment unmodifi sev tolerogen sev imped lipopolysaccharid induc matur kept dcs immatur development stage experi show simpl manipul sev use immunosuppress cargo lead inhibit dc matur	D035683;D000067128	T026;T123;T114
36,318,337	non ration human enhanc transhuman human enhanc debat last decad concern ethic issu method improv physic cognit emot state individu peopl human speci whole argument favour enhanc defend paradigm ration present clear eye logic defenc stand gain transcend typic limit speci argument correct appear adult principl abl make ration inform decis enhanc paper howev suggest ration inform choic enhanc oneself may case imposs draw l paul work transform experi argu enhanc certain moral cognit modif may give rise unbridg epistem gap key domain import gap could prove mere conting unbridg due lack inform given moment radic unbridg make someon non enhanc state inher unabl conceiv would like enhanc particular way experi key understand valu pursu enhanc may prove imposs person suffici inform make ration decis whether enhanc pose challeng human enhanc propon general transhumanist particular	D009014;D004644	T078;T041
36,318,334	mathemat descript flow spheric lymph node motion lymph import role immun system influenc poros lymph node take peripher path without enter lymphoid compart paper construct mathemat model lymph node assum spheric geometri subcapsular sinus thin spheric shell near extern wall lymph node core porous materi describ lymphoid compart mathemat formul assum incompress use stoke togeth darci brinkman equat flow lymph thank hypothesi axisymmetr flow respect azimuth angl use stream function approach find explicit solut fulli develop pulsatil flow term gegenbau polynomi select set plot provid show trend motion case physiolog paramet finit element simul perform compar explicit solut	D008954;D055641	T081;T075
36,318,325	enzym free fluoresc determin uric acid combin cdte quantum dot metal organ framework signal amplif composit cdte quantum dot qds zif elabor design synthes enzym free fluoresc probe sensit determin uric acid ua base fluoresc detect properti cdte qds signal amplif function zif structur featur composit character transmiss electron microscopi scan electron microscopi powder x ray diffract fluoresc spectrometri ad ua composit emiss cdte qds reduc due inner filter dynam quench effect ua adsorpt abil zif toward ua promot respons signal cdte qds basi ua quantifi composit concentr rang excitationemiss wavelength nm detect limit composit toward ua nm reproduc composit determin ua evalu relat standard deviat composit also exhibit merit enzym free analysi low test cost short analysi time min loos ph condit applic whole physiolog ph rang composit appli determin ua human urin recoveri spike sampl rang	D045663;D019187;D000073396	T197;T073;T109
36,318,321	novel gut inflammatori rat model laparotom inject peptidoglycan staphylococcus aureus inflammatori bowel diseas includ ulcer coliti crohn diseas global increas appropri model system requir dissect diseas pathogenesi drug screen adequ treatment present studi establish novel model gut inflamm inject peptidoglycan staphylococcus aureus use laparotom procedur three differ dose peptidoglycan ie mgkg bodi weight use treatment effect evalu studi macrophag phagocyt function spleen lymphocyt prolifer qrt pcr assess periton cell gene express addit histolog analysi gut section gastric acid immunoglobulin cytokin assess signific increas phagocyt activ mgkg bodi weight pgn group dose depend increas spleen lymphocyt prolifer signific increas total acid secret mgkg bodi weight pgn treat rat observ addit signific increment tlr cd mrna express periton cell tnf il ifn level maximum distort gut architectur observ mgkg bodi weight pgn group henc peptidoglycan aureus use establish screen model studi action mechan anti inflammatori food product drug	D010457;D013203	T123;T047;T109
36,318,296	pilot mobil tech role academ medic center often breakdown communic physic therapi nurs regard respons patient mobil communic problem contribut mobil frequent miss clinic intervent address gap mobil tech mt role implement larg academ medic center purpos articl describ implement role	D000046;D003142	T073;T080;T093;T170;T054;T097
36,318,295	impact transit care pharmacist communiti hospit discharg model pharmacist provid varieti discharg servic aid transit care purpos studi evalu impact pilot program implement unit base clinic pharmacist communiti teach hospit	D010595;D010607	T093;T097
36,318,294	intern oper metric center medicar medicaid servic hospit compar qualiti rate center medicar medicaid servic cms made sever refin model calcul hospit qualiti star rate hospit compar amidst critic evid bias institut argu cms model align import intern qualiti metric encourag measur approach redesign potenti use categor tier rather complet abandon rate system find institut characterist avail resourc averag sever ill academ affili associ intern qualiti metric relat patient flow furthermor regress result origin revis cms star rate methodolog suggest patient flow metric discharg noon p weekend discharg p posit relationship hospit compar rate hospit better patient flow measur higher level discharg noon weekend discharg associ higher cms qualiti rate find suggest cms star rate reflect key aspect oper perform specif effort improv patient flow rank system consid hospit characterist influenc intern oper move toward system capabl qualiti price transpar consum	D019985;D008484	T081;T089;T064
36,318,293	safeti effici efficaci protocol contrast enhanc imag acut stroke evalu comput tomographi angiographi perfus studi increas becom part acut stroke evalu howev volum benefit scope need imag sometim debat	D020521	T047
36,318,288	outcom allogen hematopoiet stem cell transplant follow venetoclax base therapi among aml mds patient use bcl inhibitor venetoclax ven combin hypomethyl agent chemotherapi shown efficaci treat acut myeloid leukemia aml frontlin treatment relaps allow patient bridg allogen hematopoiet stem cell transplant allo hsct howev influenc ven base therapi prognosi subsequ allogen hsct remain unknown retrospect collect data patient proceed allo hsct novemb novemb ven base therapi five transplant center zhejiang provinc china total patient analyz thirti one patient diagnos aml de novo secondari mds mds cmml major patient receiv ven base therapi treatment relaps refractori diseas receiv initi treatment patient alreadi complet remiss cr receiv ven consolid deep remiss hsct twenti seven patient cr time hsct day cumul incid grade iv acut graft versus host diseas agvhd grade ii iv agvhd respect evalu patient develop chronic gvhd year year day cytomegalovirus cmv reactiv occur patient epstein barr virus ebv reactiv occur patient median follow month overal surviv progress free surviv relaps non relaps mortal incid year respect univari multivari analysi reveal relapsedrefractori rr diseas associ inferior pfs hr ci p prior poor respons ven found signific factor predict higher risk relaps hr ci p result show ven base regimen therapi follow allo hsct aml patient feasibl increas risk transplant relat mortal toxic	D020031;D018380;D015470;D006086	T061;T047;T191
36,318,276	explor xe nmr paramet structur investig biomolecul relativist solvent thermal effect recent year studi new probe arous great interest scientif communiti around world therefor present work present potenti candid new spectroscop probe xe co nno conjug aminophenyl benzothiazol complex xeabt propos chemic shift calcul dft level perform thus factori design carri order choos best comput method best combin base function zora def tzvp function pbe consid relativist effect zora implement find reveal xe chemic shift affect thermal solvent effect consid enzymat environ signific decreas xe valu observ suggest xeabt complex may promis spectroscop probe	D014979;D013844	T196;T109
36,318,245	perceiv impact project echo network northern ireland health social care provid patient health system qualit analysi studi assess perceiv impact benefit project echo extens communiti healthcar outcom tele mentor intervent health social care provid patient health system northern ireland access specialist space share experi abl dissemin date best practic cite improv provid knowledg well improv qualiti care patient healthcar provid report confid manag patient relationship improv differ level health system echo describ improv access educ train remov geograph time barrier one first studi qualit analys impact across number differ clinic social care echo network result strong indic perceiv benefit echo improv provid patient health system outcom increas healthcar provid knowledg confid manag patient primari level health system implic futur servic design particular within context covid virtual onlin train necessit social distanc requir	D000086382	T047;T067
36,318,211	chang clinic workforc provid contracept abort care us cross section studi investig chang workforc provid contracept abort servic covid pandem	D003267;D005193	T061;T058;T033
36,318,210	use us food drug administr expedit drug develop review program orphan nonorphan novel drug approv us food drug administr fda program use alon combin expedit drug avail acceler approv breakthrough therapi fast track prioriti review drug use program includ novel drug contain previous fda approv activ moieti orphan drug intend diseas condit affect fewer peopl date comprehens evalu program use combin publish	D017277;D001688	T121;T123;T064
36,318,209	estim death attribut excess alcohol use among us adult age year alcohol consumpt lead prevent caus death us death rate fulli alcohol attribut caus eg alcohol liver diseas increas past decad includ among adult age year howev comprehens assess alcohol attribut death among popul includ partial alcohol attribut caus lack	D019973	T047;T048
36,318,208	associ hormon therapi depress menopaus cohort danish women menopaus level estrogen progesteron decreas women experi menopaus symptom includ mood disturb latter might prevent hormon therapi ht yet studi suggest use ht might associ increas risk depress	D015914;D011372	T061;T121;T039;T125
36,318,207	associ gonadotropin releas hormon analogu use subsequ use gender affirm hormon among transgend adolesc gonadotropin releas hormon analogu gnrha use puberti improv mental health among transgend gender divers tgd adolesc previous studi tgd adolesc start gnrha subsequ start gender affirm hormon gah rais concern gnrha use promot later use gah	D063106;D014189	T032;T098
36,318,206	perspect academ oncologist offer expand access investig drug expand access ea pathway permit patient treat investig medic product outsid clinic trial cancer care common indic ea sought effort requir physician manag understand oncologist perspect help illumin factor influenc patient access	D015507;D000072103	T121;T097
36,318,205	valid singl item screen cannabi sis c cannabi use disord screen routin care cannabi use preval increas frequent use intensifi risk cannabi use disord cud cud underrecogn medic set valid singl item cannabi screen could increas recognit	D002189;D002188;D019966	T121;T109;T002;T033;T047;T167;T048
36,318,198	neurodegener marker galectin apolipoprotein e elev aqueous humor eye glaucoma galectin gal apolipoprotein e apo marker activ microglia neurodegen diseas central nervous system whose target protect mous model glaucoma studi examin level gal apo human aqueous humor ah defin clinic associ glaucoma	D005902;D005901	T047
36,318,196	impact reticular pseudodrusen choriocapillari flow deficit choroid structur optic coher tomographi angiographi examin impact reticular pseudodrusen rpd choriocapillari blood flow choroid structur individu intermedi age relat macular degener amd	D015593;D008268	T047
36,318,195	combin aibp apoa aflibercept overcom anti vegf resist neovascular amd inhibit arteriolar choroid neovascular anti vegf resist repres major unmet clinic need manag choroid neovascular cnv previous report combin aibp apoa anti vegf antibodi overcom anti vegf resist laser induc cnv old mice prevent experi purpos work conduct clinic relev studi assess efficaci combin aibp apoa aflibercept treatment anti vegf resist experiment cnv differ time point laser photocoagul	D020256;D057135	T047;T046
36,318,192	typic viewpoint object better detect atyp one previous work claim canon viewpoint object readili perceiv noncanon viewpoint howev studi requir particip identifi object late perceptu process best arguabl cognit process pylyshyn extend work earli vision remov explicit need identifi object particular ask particip make intactscrambl discrimin briefli present object view either typic atyp viewpoint notabl particip identifi object discrimin nois scrambl particip sensit discrimin object present typic encount orient object present atyp depth rotat experi howev effect object present atyp pictur plane rotat oppos typic one reach statist signific experi suggest particular inform view may play critic role effect interpret enhanc percept item good exemplar probabl scene deriv high real world statist regular	D009949	T041
36,318,191	divid attent effect visual search caus object space divid attent effect observ across varieti stimuli perceptu task given rise object base space base theori divid attent object base theori assert process inform multipl object limit wherea space base theori assert process inform multipl locat limit extant result literatur collect inconsist simpl object base theori simpl space base theori divid attent use visual search task extend simultan sequenti method reveal capac limit found evid limit capac process object properti unlimit capac process featur contrast found evid separ spatial limit multipl pathway process theori account larg bodi previous result accord theori task requir object process must follow limit capac pathway therefor incur divid attent effect task depend featur contrast follow separ unlimit capac process pathway therefor incur divid attent effect	D001288;D013028	T041
36,318,190	achromat chromat perceiv contrast reduc visual peripheri loss contrast sensit eccentr well document steeper higher spatial frequenc lm cone oppon stimuli compar achromat cone oppon ask perceiv contrast depend eccentr stimuli present suprathreshold contrast test two oppos predict contrast constanc predict loss perceiv contrast across visual field regardless chang detect threshold appear depend physic contrast convers perceiv contrast may scale way detect threshold reflect proport increas stimulus contrast threshold measur perceiv contrast lm cone oppon cone oppon ach stimuli degre eccentr use afc contrast match method fovea peripheri test rang refer contrast low close detect threshold high suprathreshold contrast relat suprathreshold perceiv contrast measur detect threshold find evid hybrid model appar contrast reduc eccentr stimuli low mid contrast rang contrast constanc attain highest contrast equat similar sensit loss find differ chromat ach contrast respons	D015350;D017949	T025;T041
36,318,173	filariasi alcohol male coincident causal associ lymphat filariasi parasit diseas transmit mosquito carri minut thread like worm usual sign symptom seen patient diseas part peopl howev develop condit call elephantiasi mark sever swell arm leg breast genit descib interest case year old alcohol brought emerg depart alleg histori injuri incident found microfilariasi thorough blood smear screen case illustr need smear evalu diagnos microfilariasi also beg whether patient may suscept parasit infect due impair immun system	D004605	T047
36,318,172	applic artifici intellig earli comparison efficaci new cancer drug clinic choic among recent approv cancer drug burden absenc direct comparison term efficaci across new agent articl present ipdfromkm method artifici intellig ai applic aim facilit analys efficaci base secondari data	D009369;D000970	T121;T191;T109
36,318,171	psycholog take charg oncolog patient year studi activ psychologist piedmont aosta valley oncolog network tumor patholog bio psycho social event consequ person life point view physic psycholog relat social mental discomfort chronic pain neoplast patholog bring present case request help psychologist provid specif diagnost therapeut assist path case medic patholog less piedmont vall daosta oncolog network role coordin network servic deal care cancer patient includ relat psycho oncolog articl present data relat activ psycho oncologist network year	D008495;D001943	T191;T091
36,318,170	home care home venous access devic insert covid pandem autonom patient emerg activ daili work practic reliabl venous access essenti provid effect care mani patient various vascular access devic vad avail place special team use ultrasound guidanc dedic room hospit howev pandem covid mani autonom bedridden patient unabl reach hospit vad insert unavail ambul transport reason special team organ modal posit vad bedsid home	D000086382;D019636;D013927;D006699	T047;T046;T058;T067
36,318,169	palliat care lombardi region analysi care offer lombardi region one widespread advanc model palliat care pc countri howev relat lack updat data refer activ lombardi pc network	D017051;D010166	T061;T058;T093
36,318,168	conscienti object assist suicid switch rule last year legal weight sick person autonomi increas promot mani countri today legisl allow euthanasia andor assist suicid within law even though assist suicid could caus discomfort sick person often prefer order balanc right doctor respect ethic deontolog principl sick peopl put end suffer line need keep balanc deontolog rule medicin right sick peopl would appropri shift current legal framework consid physician assist suicid oblig doctor conscienti object except anoth envisag physician assist suicid oblig doctor consid conscienti willing except	D017236;D005065;D010820	T058;T097;T054
36,318,167	medic assist die itali bill law polit compromis two judgement italian constitut court first one relat decriminalis well defin condit articl penal code support incit commit suicid second relat referendum held regard partial repeal articl penal code murder consent parti issu physician assist suicid pas recent regul bill law approv italian chamber deputi current senat regist	D010817;D017236	T054
36,318,166	effect effici time come differ attitud health profession health system administr toward effici effect reveal inner health system tension logic produc care tension entail risk dire consequ universalist health protect system push toward dissoci care relationship privat safeguard constraint effici form access inequ generat howev effici product health mean cut qualiti care qualiti oper choic ask clinician evid base medicin administr balanc sheet valu health result health servic health system effect serv scope must administ effect treatment peopl condit benefit	D001290	T078;T055;T041
36,318,156	molecular mechan claudin strand flexibl comput studi claudin one major compon tight junction play key role format mainten epitheli barrier function tight junction strand dynam capabl adapt structur respons larg scale tissu rearrang cellular movement present molecular dynam simul claudin strand nm length two parallel lipid membran character mechan properti persist length claudin strand compar obtain analys freez fractur electron microscopi result indic later flexibl claudin strand due interplay three set interfaci interact network two antiparallel doubl row claudin membran model claudin assembl interlock tetramer ion channel along strand slide respect strand curv submicromet length scale result suggest novel molecular mechan under claudin strand flexibl also shed light intermolecular interact role maintain epitheli barrier function	D057167;D019108	T123;T116;T030
36,318,155	reconstitut depolar induc ca releas platform valid skelet muscl diseas mutat drug discoveri skelet muscl excit contract e c coupl depolar plasma membran trigger ca releas sarcoplasm reticulum sr refer depolar induc ca releas dicr dicr occur type ryanodin receptor ryr physic interact dihydropyridin receptor cav subunit specif machineri form addit essenti compon includ stac adaptor protein junctophilin exom sequenc acceler discoveri mani novel mutat gene encod dicr machineri various skelet muscl diseas howev function valid time consum must perform skelet muscl environ studi establish platform reconstitut dicr hek cell essenti compon effect transduc hek cell express ryr use baculovirus vector ca releas quantit measur r cepiaer fluoresc er ca indic without contamin extracellular ca influx cell k depend ca releas trigger chemic depolar aid inward rectifi potassium channel indic success reconstitut dicr use platform evalu sever cav mutat implic malign hyperthermia myopathi also test sever ryr inhibitor wherea dantrolen cpd inhibit dicr procain effect furthermor twitch potenti perchlor thiocyan shift voltag depend dicr negat potenti without affect ca induc ca releas result well reproduc find muscl fiber cultur myotub sinc procedur simpl reproduc reconstitut dicr platform high use valid mutat drug discoveri skelet muscl diseas	D019837;D009135	T047;T116;T192
36,318,154	conform defin rexinoid prevent inflamm nonmelanoma skin cancer compound potent rexinoid high effect cancer chemoprevent elev serum triglycerid effort separ lipid toxic anticanc activ synthes four new analog rexinoid three rexinoid elev serum triglycerid rexinoid twice potent rexinoid bind retinoid x receptor rxr tran retino acid atra play key role maintain skin homeostasi rexinoid high effect upregul gene respons biosynthesi atra inflamm play key role skin cancer rexinoid high effect diminish lps induc inflamm rexinoid high effect prevent uvb induc nonmelanoma skin cancer nmsc without display overt toxic biophys studi rexinoid bound hrxr ligand bind domain lbd reveal import conform dynam differ ligand bind domain	D013764;D012878	T191;T109
36,318,140	advers matern deliveri outcom children young age year us adolesc compar older adolesc adult studi use us claim databas compar morbid deliveri outcom among pregnant year old vs year old year old	D008423;D011253;D011256;D011248	T033;T040;T079;T046
36,318,139	request self manag medic abort provid use onlin telemedicin us state dobb v jackson women health organ decis studi assess chang onlin telemedicin request self manag abort medic vs dobb v jackson women health organ suprem court decis overturn roe v wade	D000028;D000073278;D017216;D000019;D035521	T061;T121;T039;T092;T093;T033;T089;T081;T058;T046
36,318,134	dobb decis threaten full breadth ob gyn train medic news articl discuss overturn roe v wade chang train futur obstetrician gynecologist state abort ban sever restrict	D000029;D006176;D009774;D004503;D035521;D002983	T061;T091;T080;T092;T065;T089
36,318,133	associ unintend pregnanc matern infant health outcom systemat review meta analysi unintend pregnanc common us associ advers matern infant health outcom howev estim associ specif current us popul lack	D000068104;D049168;D000068097;D011248	T033;T081;T046;T080
36,318,132	menopaus hormon therapi prevent chronic condit jama patient page summar us prevent servic task forc recommend use hormon therapi prevent chronic condit postmenopaus individu	D002908;D020249;D008593	T061;T047;T039
36,318,128	hormon therapi primari prevent chronic condit postmenopaus person updat evid report systemat review us prevent servic task forc uncertain whether hormon therapi use primari prevent chronic condit heart diseas osteoporosi type cancer	D002908;D004967;D020249;D017698;D011372	T061;T121;T039;T109;T040;T033;T125;T047
36,318,127	hormon therapi primari prevent chronic condit postmenopaus person us prevent servic task forc recommend statement menopaus defin cessat person menstrual cycl defin retrospect month final menstrual period perimenopaus menopaus transit year time period preced person final menstrual period character increas menstrual cycl length variabl period amenorrhea often symptom vasomotor dysfunct preval incid chronic diseas eg cardiovascular diseas cancer osteoporosi fractur increas age us person reach menopaus expect averag live anoth year	D002908;D004967;D017698;D011372;D020249;D006728	T039;T121;T061;T109;T040;T033;T125;T047
36,318,126	challeng emerg abort care follow dobb rule viewpoint discuss limit block access legal abort affect provis emerg critic care includ negat effect patient health legal intrus patient physician decis make process concern legal jeopardi	D000028;D004632;D006297;D035521	T061;T080;T092;T093;T033;T089;T081;T058;T046
36,318,125	interoper post roe era sustain progress protect reproduct health inform viewpoint propos solut better safeguard reproduct health inform patient record complet owe interoper health inform exchang network	D060728;D035521;D000073892	T089;T092;T058;T091
36,318,124	confront medic communiti complic margin abort care viewpoint discuss exclus abort care mani establish medic sourc hospit coverag mani major payer health care system legitim ensur clinician train safe abort care	D000028;D028661;D006297	T061;T078;T080;T093;T033;T081;T046
36,318,123	legal risk ethic dilemma clinician aftermath dobb viewpoint discuss way suprem court rule dobb v jackson women health organ trigger abort ban restrict half state present serious legal risk clinician major ethic dilemma	D000028;D010820;D035521;D006297	T061;T080;T092;T093;T033;T097;T081;T089;T046
36,318,122	shift crimin legal abort argentina viewpoint discuss passag implement law legal abort argentina certain circumst examin ongo clinic issu legal challeng law	D000028;D000024	T061;T093;T033;T081;T046
36,318,121	self manag abort us viewpoint detail clinician treat patient self manag abort without put patient risk crimin	D000028;D000073278;D012648	T061;T093;T033;T056;T081;T058;T046
36,318,120	advanc birth equiti post dobb us viewpoint discuss us suprem court decis dobb v jackson women health organ describ decis threaten birth equiti racial social group suggest reproduct justic approach address racial social inequ ensur reproduct freedom autonomi peopl	D000029;D000069576;D035521;D046269	T061;T078;T080;T092;T089
36,318,119	implic dobb decis medic educ inadequ train moral distress viewpoint discuss state restrict abort affect medic student train provid reproduct health care also creat moral distress forc provid care may harm patient	D004501;D009014;D035521	T065;T092;T089;T078
36,318,108	dissoci adsorpt water camn cation cluster water split catalyz photosystem ii compris inorgan core camn protein ligand understand evolut camn attach water molecul isol camn cluster investig use vibrat spectroscopi densiti function theori calcul comput find suggest water molecul adsorb ca atom atom water one oh bond form hydrogen bond oxo bridg dissoci two oh group consist fact isom molecular adsorb water experiment observ	D014867;D010100	T121;T197;T196;T123
36,318,069	simul dark field x ray microscopi imag wavefront propag techniqu dark field x ray microscopi diffract base synchrotron imag techniqu capabl imag defect bulk extend crystallin sampl numer simul present imag format microscop use numer integr dynam takagi taupin equat wavefront propag approach valid compar simul imag experiment data near perfect singl crystal diamond contain singl stack fault defect illumin volum	D008853;D017356	T059;T073
36,318,068	extend novel base phase algorithm solut anomal scatter substructur sad data protein crystal owe import singl wavelength anomal diffract sad techniqu recent develop base phase algorithm incorpor inner pixel preserv ipp procedur rius torrell acta cryst adapt determin anomal scatter substructur applic test seri repres experiment data set most retriev protein data bank give idea suitabl data set main indic measur qualiti also given domin anomal scatter either semet atom metalsclust incorpor soak result sad adapt algorithm solv substructur test protein crystal quit effici	D011506;D000465	T123;T170;T116
36,318,050	one session treatment compar multisess cbt children age year specif phobia aspect non inferior rct children young peopl specif phobia signific affect mental health develop daili function cognit behaviour therapi base intervent remain domin treatment limit provis warrant investig low intens altern one session treatment one altern share cognit behaviour therapi principl shorter treatment period	D015928;D000086382;D010698	T061;T047;T067;T048
36,318,008	medic biographi isak samokovlija famous bosnian herzegovinian writer purpos paper shed light biograph profession health educ work dr isak samakovlija better known writer doctor countri born born gorad easternmost provinc austrian hungarian monarchi modest jewish merchant famili attend high school sarajevo complet studi medicin vienna first world war serv twice austro hungarian armi end first world war complet medic internship nation hospit sarajevo began servic doctor first gorad fojnica sarajevo establish independ state croatia may dismiss duti servic without right pension support without right appeal independ state croatia twice mobil home guard manag clinic alipain refuge camp world war ii head health educ depart ministri public health peopl republ bosnia herzegovina sarajevo togeth group enthusiast doctor found edit first bosnian medic journal ivot zdravlj life health journal dr samokovlija publish articl health educ content dr samokovlija left ministri public health continu edit literatur art journal brazda still privat practic end life die sarajevo januari buri highest state honor jewish cemeteri sarajevo conclus isak samakovlija one first medic doctor born bosnia herzegovina made signific contribut improv peopl health first second world war place work special contribut articl health educ	D011634;D006761	T091;T093;T073
36,318,007	measur vaccin effect observ studi design herein present bird eye view common observ studi design util measur vaccin effect assess vaccin effect integr part vaccin research particular newli develop vaccin cohort studi prospect direct exposur one outcom design best method ascertain attack rate infecti diseas tradit case control studi retrospect direct given outcom one exposur design provid relat risk provid odd ratio good estim relat risk attack rate low critic depend laboratori test result perform test negat case control studi design anoth type observ studi common use nowaday evalu vaccin effect compar cohort tradit case control design conduct test negat case control studi relat cheaper faster herein describ mention studi design exampl generat mont carlo simul program assum real world condit conclus simul show regardless studi design employ diagnost test specif utmost import provid valid estim vaccin effect	D000087507;D014612	T081;T129;T121;T116
36,318,005	pseudohyponatremia secondari hypercholesterolemia set intrahepat cholestasi due metastat liver diseas case report review literatur describ rare case pseudohyponatremia set hypercholesterolemia caus cholestasi due metastat liver diseas provid review publish case literatur	D006937;D007010;D002780;D002779;D009369	T047;T191
36,318,004	text neck syndrom disentangl new epidem aim report provid brief review predispos factor text neck syndrom along diagnost therapeut approach young adult popul text neck pain worldwid public health problem larg report nowaday current data shown erron use person comput cell phone might correl develop various clinic symptom defin text neck syndrom modifi radic chang everyday life may amelior power forc cervic spine lead cervic degener along development medic psycholog social complic attribut text neck syndrom conclus new technolog potenti harm addict cell phone comput read text induc epidem text neck syndrom focus postur correct pain allevi better qualiti life achiev patient predispos factor therapeut approach syndrom affect public health remain elucid	D060145	T170;T052;T066
36,318,003	research phenomenon poor ovarian respond manag strategi ivf narrat review narrat review aim summar latest studi publish concern manag protocol adopt poor ovarian respons por case patient defin poor respond show minim respons control ovarian hyperstimul although standard definit por although infertil specialist endeavor improv cycl outcom poor respond adopt multipl manag strategi still estim risk cycl cancel studi perform studi period evalu result record latest publish protocol improv oocyt retriev poor respond includ anti mllerian hormon clomiphen citrat co enzym q corifollitropin dehydroepiandrosteron doubl stimul follicl stimul hormon growth hormon gonadotropin releas hormon agonist letrozol human chorion gonadotropin lutein hormon progesteron testosteron conclus although mani strategi suggest manag por none proven superior other larg scale random studi need valid experiment techniqu lead toward success individu treatment regimen	D010062;D054315	T061
36,318,002	comparison effect wycop video laryngoscop c mac video laryngoscop direct laryngoscop intub elect surgeri patient airway manag undergon dramat transform sinc arriv video laryngoscop vl vl higher intub success rate first tri lower complic comparison direct laryngoscop dl use vl recommend intub covid patient speed intub time reduc failur rate team airlangga univers develop wycop video laryngoscop wycop vl vl wi fi connect smartphon easier vl low cost studi aim compar effect wycop vl c mac video laryngoscop c mac vl dl	D020704;D000086382	T047;T074;T067
36,318,001	morphometr analysi supraorbit foramen notch popul bosnia herzegovina aim studi learn morpholog characterist supraorbit foramen determin precis posit relat surround anatom landmark adult popul bosnia herzegovina	D005624;D009915	T023;T030
36,318,000	partial superfici parotidectomi versus extracapsular anatom dissect treatment benign parotid tumor superfici benign parotid tumor common neoplasm salivari gland differ surgic procedur appli partial superfici parotidectomi psp extracapsular dissect ecd two predomin surgic techniqu studi aim evalu psp versus ecd benign parotid tumor relat post oper complic recurr rate	D010307	T191
36,317,999	potenti cinnamon extract cinnamomum burmanii anti insomnia medic hypothalamus pituitari adren axi improv rat studi aim explor efficaci cinnamon extract anti insomnia medic experiment anim evalu level hormon neurotransmitt relat insomnia	D007319;D027424	T184;T047;T002;T048
36,317,998	evalu sar cov antibodi respons post third dose covid mrna vaccin universita indonesia hospit longev vaccin effect antibodi titer moderna mrna covid vaccin booster healthcar worker indonesia known	D000917;D000086382	T047;T067;T038
36,317,995	role circular rnas multipl sclerosi neuroimmun disord recent year non code rnas receiv increas attent import epigenet mechan particular role micro rnas regul mirna express high dynam complex grow evid suggest exist anoth higher level regulatori mechan involv mirna activ circular rnas circrna circrna repres novel uniqu class endogen ncrnas control express function mirna call natur mirna spong accumul evid reveal circrna role physiolog patholog process includ cns immun regul previous studi implic mirna regul autoimmun demyelin ms multipl sclerosi chronic neurolog inflammatori demyelin disord central nervous system etiolog ms still fulli understood accumul evid suggest multifactori entiti signific involv autoimmun process	D009103;D035683;D009422	T123;T047;T114
36,317,994	role mcpip protein lipid metabol liver homeostasi non alcohol fatti liver diseas non alcohol fatti liver diseas nafld character excess accumul lipid hepatocyt among nafld patient diseas progress nonalcohol steatohepat character addit develop inflamm fibrosi liver current estim world popul suffer nafld mcpip protein rnase describ negat regul inflamm also mcpip play role lipid metabol inhibit process adipogenesi mice delet zcha gene character dyslipidemia reduc bodi fat content case ischemia reperfus injuri liver mcpip protect inflamm damag organ lipid accumul hepatocyt associ decreas mcpip level addit mcpip may influenc ppar mediat lipogenesi process presenc mcpip myeloid leukocyt liver epitheli cell crucial mainten liver homeostasi	D065626	T047
36,317,993	stimul effect metal biosynthesi plant bioactiv compound secondari metabolit produc plant rich group bioactiv compound mani health promot properti use various sector industri includ pharmaceut cosmet industri one problem applic plant deriv compound low level plant tissu thus new method aim stimul biosynthesi plant metabolit investig recent year sever articl use metal elicitor publish present review present exampl applic copper cu zin zn cadmium cd select nanoparticl elicitor	D015032;D002104	T123;T196;T121;T131
36,317,992	dna base predict human phenotyp trait medico legal forens purpos studi aim present current state knowledg dna base predict human extern visibl characterist unknown person base crime scene biolog materi left behind dna sampl refer biolog wit procedur call forens dna phenotyp fdp analyt part work base scholar articl publish electron search relev refer conduct accord prisma methodolog march ebsco discoveri servic ed adam mickiewicz univers librari googl scholar molecular basi fdp dna marker use predict sex age biogeograph origin extern visibl trait pigment skin eye hair colour hair morpholog facial morpholog presenc freckl bodi height bodi weight obes male pattern bald myopia describ furthermor methodolog difficulti result polygen inherit studi trait well social ethic problem accompani forens dna phenotyp discuss final key theme futur research relat forens dna phenotyp outlin	D005127;D053803	T032;T091
36,317,991	argonaut protein cell biolog plant develop argonaut ago protein integr part regulatori pathway control small rna srna fundament proper function eukaryot cell ago high special platform bind specif srna coordin gene silenc interact protein factor form rna induc silenc complex risc contribut endonucleolyt cleavag target mrna andor influenc translat process increas number evid confirm particip ago protein sever cellular process ie transcript regul sequestr rna depend methyl dna repair dna damag synthesi sirna independ dcl dicer like protein co transcript regul mirna gene express intron splice particular plant speci character presenc differ number ago protein mani case yet unknown regulatori andor biolog function review articl cover current knowledg function ago cell biolog plant develop	D060565;D035683	T123;T116;T114
36,317,990	pharmacolog chaperon therapi treatment inborn error metabol articl describ mechan molecular pharmacolog chaperon treatment inborn error metabol literatur review usag ambroxol act pharmacolog chaperon beta glucocerebrosidas gaucher diseas parkinson diseas associ gba variant review	D005776;D000551;D010300	T121;T047;T109
36,317,989	crisprca intellig immun system bacteria archea invent crispr consid one breakthrough discoveri recent year histori biolog biotechnolog medicin well pharmaceut agricultur industri method develop use crispr creat new previous unattain possibl signific improv qualiti life invent intellig immun system present day much research done use crisprca system result studi develop modern tool genet manipul allow introduct mani modif within dna may contribut silenc express given gene overexpress eg mutat delet paper describ applic method genet manipul use second class system crisprca advantag method advantag previous use genet engin tool well limit disadvantag signific limit possibl applic potenti use method also present well research carri use crsprcas	D064113;D000072669	T063;T040
36,317,988	parent age assist reproduct technolog analysi risk chronic diseas progeni concept child advanc parent age year steadili increas recent decad especi develop countri socio econom factor effect contracept avail assist reproduct technolog art direct impact postpon decis babi art enabl reproduct success peopl diagnos infertil reduc possibl becom pregnant due concomit patholog epidemiolog studi indic advanc parent age art associ patholog pregnanc gestat diabet risk pre eclampsia miscarriag placent abrupt preterm labor stillbirth neurodevelopment disord chronic diseas offspr work focus avail inform metabol chang increas risk develop cardiovascular diseas offspr parent advanc age conceiv art final address sourc observ disturb gamet embryo level relat oxygen stress epigenet modif dna damag consid possibl rescu action	D047928	T046
36,317,987	molecular mechan progesteron action femal reproduct system progesteron p steroid hormon particip mani process femal reproduct system hormon produc main corpus luteum cl howev also ovarian follicl uterin tissu placenta abl produc p progesteron involv regul sexual cycl well initi mainten pregnanc hormon may affect cell function genom mechan nuclear p receptor pgr via nongenom mechan membran p receptor progesteron receptor membran compon pgrmc membran progestin receptor mpr genom mechan p action lead express target gene synthesi new protein nongenom mechan modifi various intracellular signal pathway integr two mechan p activ lead suitabl regul cell tissu consequ respons organ hormon	D011374;D011980	T123;T121;T116;T109;T192;T125
36,317,986	soft laser applic area oral surgeri stomatolog low level laser lll use stomatolog oral surgeri field dentistri due biostimul biomodul photodynam effect heal process soft tissu bone wound acceler indic oral surgeri achiev faster bone heal tooth extract also improv osseointegr implant advantag stomatolog pain allevi improv heal aphtha cold sore well symptom relief mucos due use free side effect low time effort lll offer high patient comfort	D019242	T091
36,317,981	covid mortal usual occup industri state new york citi unit state object report describ covid mortal among us resid state new york citi usual occup industri	D000086382	T047;T067
36,317,979	target neonat echocardiographi patient hemodynam instabl target neonat echocardiographi tne increas use bedsid neonat care provid enhanc understand physiolog affect manag hemodynam unstabl patient tradit method bedsid assess includ blood pressur heart rate monitor capillari refil unabl provid complet pictur tissu perfus oxygen tne allow precis medicin provid tool identifi pathophysiolog continu reassess rapid chang hemodynam relationship cardiolog integr train well qualiti assur imper congenit heart diseas rule util tne hemodynam manag pathophysiolog vari substanti assess manag patient congenit heart diseas util tne longitudin hemodynam assess requir extens train field continu grow guidelin protocol train indic essenti ensur optim use provid platform qualiti assur	D006330;D014652	T019;T047
36,317,978	analgesia sedat anesthesia neonat cardiac diseas analgesia sedat anesthesia continuum diagnost andor therapeut procedur newborn often requir analgesia sedat andor anesthesia newborn general particular heart diseas increas risk serious advers event includ mortal anesthesia section discuss assess manag pain discomfort intervent review dose side effect common use medic provid recommend use newborn heart diseas procedur requir deeper level sedat anesthesia airway hemodynam support might necessari although associ long term deleteri neurocognit effect anesthet agent receiv consider attent scientif lay press causal establish nonetheless earli multimod multidisciplinari approach benefici safe manag intervent procedur surgeri avoid problem toler delirium contribut long term cognit dysfunct	D000698;D000758;D006331	T061;T047
36,317,976	care fetus congenit cardiovascular diseas diagnosi deliveri major congenit cardiovascular diseas includ structur cardiac defect abnorm cardiac function rhythm disturb identifi prenat use screen obstetr ultrasound referr fetal echocardiogram indic	D002318;D006330	T019;T047
36,317,975	preoper manag neonat congenit heart diseas clinician care neonat congenit heart diseas encount challeng clinic care infant await surgeri evalu potenti intervent newborn heart diseas present signific pathophysiolog heterogen therefor requir person therapeut manag plan howev complex field neonat cardiac hemodynam simplifi explor clinic quandari includ specif section review anatom challeng patient propos serv primer focus hemodynam therapeut strategi preoper neonat systol dysfunct diastol dysfunct excess pulmonari blood flow obstruct pulmonari blood flow obstruct system blood flow transposit physiolog singl ventricl physiolog	D006330	T019
36,317,974	bioethic neonat cardiac care clinician care neonat congenit heart diseas encount challeng ethic implic daili practic must basic fluenci ethic principl practic applic	D001675	T091
36,317,973	evalu manag noncardiac comorbid children congenit heart diseas outcom patient neonat heart diseas affect numer noncardiac genet factor includ neonat concern prematur low birth weight congenit anomali airway pulmonari gastrointestin genitourinari anomali genet syndrom section serv summari issu may affect evalu manag neonat heart diseas noncardiac factor heavili influenc condit common neonatologist make strong argument multidisciplinari care neonatologist cardiologist surgeon anesthesiologist cardiovascular intensivist section project aim facilit comprehens approach care neonat congenit heart diseas	D006330;D007235	T019;T047
36,317,972	nutrit consider neonat congenit heart diseas import nutrit manag critic ill infant congenit heart diseas chd foundat optim short long term health outcom growth failur malnutrit common infant chd etiolog growth failur popul often multifactori may relat alter metabol demand compromis blood flow intestin lead nutrient malabsorpt cellular hypoxia inadequ energi intak poor oral motor skill dearth high qualiti studi gap previous publish guidelin led wide variabl nutrit practic local driven review provid recommend nutrit subgroup neonat cardiac care collabor best evid base practic provis nutrit support infant chd review evid recommend focus predefin area clinic care target popul infant month chd admit icu inpati ward area includ energi need nutrient requir enter nutrit feed practic parenter nutrit outcom futur progress direct qualiti improv effort optim periop nutrit manag increas emphasi individu care base nutrit status cardiorespiratori physiolog state ill vulner	D004750;D006330	T061;T019;T074
36,317,971	acut cardiac care neonat heart diseas manuscript one compon larger seri articl produc neonat cardiac care collabor publish supplement pediatr review articl summar contemporari physiolog principl evalu manag acut care issu neonat complex congenit heart diseas multidisciplinari team author creat collabor execut committe author develop detail outlin manuscript small team author assign draft specif section author review literatur focus origin manuscript publish last decad draft preliminari content recommend author subsequ review edit entir manuscript consensus achiev topic address includ cardiopulmonari interact pathophysiolog strategi minim develop ventil induc low cardiac output syndrom common postop physiolog periop bleed coagul common postop complic	D002303;D003422	T033;T058;T046
36,317,967	optim neurodevelopment outcom neonat congenit heart diseas neurodevelopment impair common import long term morbid among infant congenit heart diseas chd half complex chd demonstr form neurodevelopment neurocognit andor psychosoci dysfunct requir special care impact long term qualiti life prevent brain injuri treat long term neurolog sequela high risk clinic popul imper improv neurodevelopment psychosoci outcom thus cardiac neurodevelopment care forefront clinic research effort initi research primarili focus neurocrit care oper strategi mitig brain injuri field evolv investig shift understand prenat genet environment contribut impair neurodevelop articl summar recent literatur detail brain abnorm affect neurodevelop children chd impact genet neurodevelopment outcom best practic neonat neurocrit care focus development care parent support new area import framework also provid infrastructur resourc need support chd famili across continuum care set	D006330;D065886;D001930	T019;T037;T048
36,317,960	sustain dentistri part ii sustain workplac wast manag second final part public topic sustain dental practic deal call workplac manag describ work process consumpt energi materi practic wast manag also address discuss path resourc practic dispos recycl final exampl materi research present use implant	D017132;D018505	T068;T082
36,317,936	transform evalu agrochem present agrochem safeti evalu paradigm long stand anchor well establish test evalu procedur howev meet present day challeng rapid grow popul food insecur pressur climat chang transform current framework appli modern evalu strategi better support sustain agricultur health environment scienc institut hesi assembl technic committe refram safeti evalu crop protect product committe compos intern expert regulatori agenc academia industri nongovernment organ mission establish framework support develop fit purpos agrochem safeti evalu applic chang global well local need regulatori decis incorpor relev evolv scienc accomplish integr state art scientif method technolog data sourc inform safeti risk decis adapt evolv local global need project team use system think approach develop tool implement problem formul exposur driven approach creat sustain safe effect crop protect product reduc replac refin anim studi fit purpos assay new approach necessarili integr modern tool latest advanc chemic test method guarante robust human environment safeti risk assess agrochem articl summar challeng associ modern agrochem safeti evalu propos potenti roadmap seek input engag broader communiti advanc effort health environment scienc institut hesi pest manag scienc publish john wiley son ltd behalf societi chemic industri	D016573;D000069601	T120;T057
36,317,919	efficaci nitrit therapi treatment heart failur meta analysi random control trial efficaci nitrit therapi treatment heart failur remain controversi conduct systemat review meta analysi explor impact nitrit therapi heart failur	D006333;D012749	T047;T046
36,317,918	surgeri fate patient lerich syndrom endovascular therapi result earli follow outcom research aim present earli follow result endovascular treatment patient lerich syndrom singl center	D007925;D019917;D057510	T061;T047
36,317,917	earli clinic outcom thoracoscop mitral valvuloplasti first case report case thoracoscop mitral valvuloplasti earli stage sought analyz earli clinic outcom	D008944;D006348	T061;T047
36,317,916	summari experi result transesophag ultrasound guid ventricular septal defect atrial septal defect closur oper ventricular septal defect vsd atrial septal defect asd congenit heart diseas techniqu transthorac closur tc percutan closur pc treatment vsd asd continu improv matur studi aim retrospect analyz therapeut effect tc pc vsd asd patient	D006345;D006344	T019
36,317,915	embol aortopulmonari collater arteri cooper valv conduit attach right ventricular outflow tract patient tetralog fallot repair one stop procedur describ one stop procedur aortopulmonari collater arteri apca postop complic tetralog fallot tof postop complic tof includ right ventricular outflow tract stenosi pulmonari valvular annular stenosi pulmonari regurgit aortopulmonari arteri stenosi one stop procedur defin apca embol heart continu function cardiopulmonari bypass median sternotomi reconstruct right ventricular outflow tract valv conduit replac aortopulmonari arteri biolog valv sew within valv conduit artifici blood vessel vitro subsequ use procedur achiev signific result	D013771	T019
36,317,914	applic high frequenc oscil ventil combin volum guarante preterm infant acut hypox respiratori failur patent ductus arteriosus ligat studi aim evalu efficaci safeti high frequenc oscil ventil combin volum guarante hfov vg preterm infant acut hypoxem respiratori failur ahrf patent ductus arteriosus ligat	D004374;D012127;D006612;D012128;D012131	T061;T019;T047;T046
36,317,913	case stanford type acut aortic dissect preoper extens cerebr infarct success treat surgic patient organ malperfus acut aortic dissect aad poor outcom surgic indic patient aad complic extens cerebr infarct establish report success treat surgic case patient cerebr infarct stanford type aad year old man admit hospit chief complaint left paresi confirm cerebr hemorrhag head comput tomographi incis right neck right intern carotid arteri ligat close emerg surgeri perform mm triplex raft ascend aorta replac bypass perform prosthet graft right axillari arteri cerebr hemorrhag neurolog issu observ postop indic possibl surgic intervent treatment strategi diseas	D000784;D019917	T061;T047;T046

36,318,360

inhibit kifa suppress replic influenza virus inhibit viral entri influenza virus iav caus sever pandem therefor mani ongo effort identifi novel antivir therapeut strategi includ vaccin antivir drug howev influenza virus continu undergo antigen drift shift result emerg mutat virus turn decreas effici exist vaccin antivir drug control iav infect therefor studi sought identifi altern therapeut strategi target host cell factor rather virus avoid infect mutat virus particular investig role kifa one kinesin superfamili protein replic iav kifa increas viral protein level iav infect cell regul initi entri stage viral infect furthermor kifa inhibitor signific suppress viral replic protect mice morbid mortal therefor find demonstr kifa high involv viral replic process viral propag vitro vivo could thus use target develop novel antivir drug

D009980;D007251

T005;T047

36,318,359

express purif intracrin human fgf studi fgfr depend biolog activ fibroblast growth factor fgf one intracrin fgfs ifgf function within cell unlik canon fgfs fgf remain intracellular play biolog role fgf receptor fgfr independ manner establish express system recombin fgf protein e coli investig whether extracellular administr fgf activ cellular signal human fgf two isoform fgfa fgfb depend presenc nuclear local sequenc nlss n terminus two isoform unstabl prepar fgfa mut substitut three cystein residu nls serin fgfb c c termin truncat introduct mutat nls improv solubl fgf prepar e coli exogen addit fgfb fgfb c balbt increas cell prolifer fgfa mut exert effect fgfb c show higher cell prolifer activ fgfr signal fgfb cell prolifer activ fgfb fgfb c block fgfr inhibitor recombin fgfr confirm fgfr depend extracellular activ fgfb analysi circular dichroism suggest c terminus fgf helic structur may affect interact fgfr result suggest n c terminus recombin fgf involv activ fgfr result provid novel insight function mechan fgf may aid develop use ligand fgfr regul

D004926;D005346

T123;T007;T116

36,318,358

cytoplasm molecular chaperon pseudomona speci pseudomona widespread various environment host nich promot rejuven cellular protein homeostasi must fine tune respons divers stress extrem high low temperatur oxid stress desicc result protein homeostasi imbal molecular chaperon function key compon aid protein fold prevent protein denatur pseudomona ecolog import bacteri genus includ human plant pathogen well growth promot symbiont speci use bioremedi review focus protein qualiti control system particular molecular chaperon ecolog divers speci pseudomona includ opportunist human pathogen pseudomona aeruginosa plant pathogen pseudomona syringa soil speci pseudomona putida psychrophil pseudomona antarctica

D044224;D018832

T123;T007;T116

36,318,352

effect wean feed provis time perform sever behaviour trait post wean lamb aim present studi assess wean time morn even feed provis immedi h delay influenc growth perform express juvenil lamb behaviour immedi age day old forti lamb random assign group e even immedi e even delay morn immedi morn delay lamb especi activ first hour wean howev activ within first h wean main affect circadian rhythm sinc lamb activ day compar night hand effect alfalfa hay provis lamb activ first h observ age day old bodi weight measur isol flight distanc test implement signific differ among lamb bodi weight number jump heart rate assess isol test flight distanc howev number vocal lower th day p e compar e lamb breed also slight affect th day p averag heart rate lamb greater valu karagouniko compar chio lamb conclud discern effect wean feed time observ growth perform display stress induc behaviour compon juvenil lamb till age day old

D034561

T015

36,318,350

influenc bacteri biopolym physic properti experiment limeston block articl describ consolid effect bacteri biopolym synthes biofilm bacteria colon mayan limeston build surfac properti limeston block includ disaggreg hard total color chang laboratori level biopolym evalu produc bacteri isol tmb tmb tmb tmb influenc surfac properti differ level rrna gene sequenc analysi show isol tmb relat psychrobact sp strain marseill p tmb relat agrococcus terreus strain bt isol tmb tmb relat xanthomona citri pv mangiferaeindica strain xc biopolym reduc surfac disaggreg materi compar untreat control reveal peel test follow biopolym b remain biopolym neglig effect cactus biopolym reduc disaggreg higher level hand similar concomit increas surfac hard limeston sampl coat biopolym biopolym b higher biopolym c total color chang treatment threshold valu indic non signific color alter partial chemic character best perform biopolym suggest probabl glycoprotein natur whose constitut acid monosaccharid probabl contribut higher adher limeston surfac contribut surfac stabil harden surfac decreas surfac decohes preliminari find suggest potenti applic bioconsolid studi requir

D002119;D001419

T121;T197;T007

36,318,345

featur select approach identifi potenti plasma metabolit postmenopaus osteoporosi patient postmenopaus women osteoporosi pmop prone fragil fractur osteoporosi associ alter level specif circul metabolit

D015663;D010024

T047

36,318,344

small extracellular vesicl load immunosuppress mirna lead inhibit dendrit cell matur particular condit inhibit immun respons requir prevent tissu damag among condit diseas caus reactiv immun respons autoimmun allerg disord immin organ reject transplant avoid tissu damag drug mediat system immun suppress option come high cost form suscept viral bacteri infect thus induct antigen specif toler prefer extracellular vesicl ev capabl deliv antigen togeth immunosuppress signal may use specif induc antigen specif toler howev natur occur ev heterogen show immunosuppress charact trial engin cell cultur deriv ev increas tolerogen potenti equip immunosuppress mirna mimic small ev sev isol purifi human monocyt thp cell line healthi donor peripher blood mononuclear cell electropor mir mir mimic acquir immunosuppress potenti modifi sev demonstr abil alter major histocompat complex molecul co stimulatori receptor present dendrit cell dcs avoid allogen respons cell produc sev serv also recipi cell contrast treatment unmodifi sev tolerogen sev imped lipopolysaccharid induc matur kept dcs immatur development stage experi show simpl manipul sev use immunosuppress cargo lead inhibit dc matur

D035683;D000067128

T026;T123;T114

36,318,337

non ration human enhanc transhuman human enhanc debat last decad concern ethic issu method improv physic cognit emot state individu peopl human speci whole argument favour enhanc defend paradigm ration present clear eye logic defenc stand gain transcend typic limit speci argument correct appear adult principl abl make ration inform decis enhanc paper howev suggest ration inform choic enhanc oneself may case imposs draw l paul work transform experi argu enhanc certain moral cognit modif may give rise unbridg epistem gap key domain import gap could prove mere conting unbridg due lack inform given moment radic unbridg make someon non enhanc state inher unabl conceiv would like enhanc particular way experi key understand valu pursu enhanc may prove imposs person suffici inform make ration decis whether enhanc pose challeng human enhanc propon general transhumanist particular

D009014;D004644

T078;T041

36,318,334

mathemat descript flow spheric lymph node motion lymph import role immun system influenc poros lymph node take peripher path without enter lymphoid compart paper construct mathemat model lymph node assum spheric geometri subcapsular sinus thin spheric shell near extern wall lymph node core porous materi describ lymphoid compart mathemat formul assum incompress use stoke togeth darci brinkman equat flow lymph thank hypothesi axisymmetr flow respect azimuth angl use stream function approach find explicit solut fulli develop pulsatil flow term gegenbau polynomi select set plot provid show trend motion case physiolog paramet finit element simul perform compar explicit solut

D008954;D055641

T081;T075

36,318,325

enzym free fluoresc determin uric acid combin cdte quantum dot metal organ framework signal amplif composit cdte quantum dot qds zif elabor design synthes enzym free fluoresc probe sensit determin uric acid ua base fluoresc detect properti cdte qds signal amplif function zif structur featur composit character transmiss electron microscopi scan electron microscopi powder x ray diffract fluoresc spectrometri ad ua composit emiss cdte qds reduc due inner filter dynam quench effect ua adsorpt abil zif toward ua promot respons signal cdte qds basi ua quantifi composit concentr rang excitationemiss wavelength nm detect limit composit toward ua nm reproduc composit determin ua evalu relat standard deviat composit also exhibit merit enzym free analysi low test cost short analysi time min loos ph condit applic whole physiolog ph rang composit appli determin ua human urin recoveri spike sampl rang

D045663;D019187;D000073396

T197;T073;T109

36,318,321

novel gut inflammatori rat model laparotom inject peptidoglycan staphylococcus aureus inflammatori bowel diseas includ ulcer coliti crohn diseas global increas appropri model system requir dissect diseas pathogenesi drug screen adequ treatment present studi establish novel model gut inflamm inject peptidoglycan staphylococcus aureus use laparotom procedur three differ dose peptidoglycan ie mgkg bodi weight use treatment effect evalu studi macrophag phagocyt function spleen lymphocyt prolifer qrt pcr assess periton cell gene express addit histolog analysi gut section gastric acid immunoglobulin cytokin assess signific increas phagocyt activ mgkg bodi weight pgn group dose depend increas spleen lymphocyt prolifer signific increas total acid secret mgkg bodi weight pgn treat rat observ addit signific increment tlr cd mrna express periton cell tnf il ifn level maximum distort gut architectur observ mgkg bodi weight pgn group henc peptidoglycan aureus use establish screen model studi action mechan anti inflammatori food product drug

D010457;D013203

T123;T047;T109

36,318,296

pilot mobil tech role academ medic center often breakdown communic physic therapi nurs regard respons patient mobil communic problem contribut mobil frequent miss clinic intervent address gap mobil tech mt role implement larg academ medic center purpos articl describ implement role

D000046;D003142

T073;T080;T093;T170;T054;T097

36,318,295

impact transit care pharmacist communiti hospit discharg model pharmacist provid varieti discharg servic aid transit care purpos studi evalu impact pilot program implement unit base clinic pharmacist communiti teach hospit

D010595;D010607

T093;T097

36,318,294

intern oper metric center medicar medicaid servic hospit compar qualiti rate center medicar medicaid servic cms made sever refin model calcul hospit qualiti star rate hospit compar amidst critic evid bias institut argu cms model align import intern qualiti metric encourag measur approach redesign potenti use categor tier rather complet abandon rate system find institut characterist avail resourc averag sever ill academ affili associ intern qualiti metric relat patient flow furthermor regress result origin revis cms star rate methodolog suggest patient flow metric discharg noon p weekend discharg p posit relationship hospit compar rate hospit better patient flow measur higher level discharg noon weekend discharg associ higher cms qualiti rate find suggest cms star rate reflect key aspect oper perform specif effort improv patient flow rank system consid hospit characterist influenc intern oper move toward system capabl qualiti price transpar consum

D019985;D008484

T081;T089;T064

36,318,293

safeti effici efficaci protocol contrast enhanc imag acut stroke evalu comput tomographi angiographi perfus studi increas becom part acut stroke evalu howev volum benefit scope need imag sometim debat

D020521

T047

36,318,288

outcom allogen hematopoiet stem cell transplant follow venetoclax base therapi among aml mds patient use bcl inhibitor venetoclax ven combin hypomethyl agent chemotherapi shown efficaci treat acut myeloid leukemia aml frontlin treatment relaps allow patient bridg allogen hematopoiet stem cell transplant allo hsct howev influenc ven base therapi prognosi subsequ allogen hsct remain unknown retrospect collect data patient proceed allo hsct novemb novemb ven base therapi five transplant center zhejiang provinc china total patient analyz thirti one patient diagnos aml de novo secondari mds mds cmml major patient receiv ven base therapi treatment relaps refractori diseas receiv initi treatment patient alreadi complet remiss cr receiv ven consolid deep remiss hsct twenti seven patient cr time hsct day cumul incid grade iv acut graft versus host diseas agvhd grade ii iv agvhd respect evalu patient develop chronic gvhd year year day cytomegalovirus cmv reactiv occur patient epstein barr virus ebv reactiv occur patient median follow month overal surviv progress free surviv relaps non relaps mortal incid year respect univari multivari analysi reveal relapsedrefractori rr diseas associ inferior pfs hr ci p prior poor respons ven found signific factor predict higher risk relaps hr ci p result show ven base regimen therapi follow allo hsct aml patient feasibl increas risk transplant relat mortal toxic

D020031;D018380;D015470;D006086

T061;T047;T191

36,318,276

explor xe nmr paramet structur investig biomolecul relativist solvent thermal effect recent year studi new probe arous great interest scientif communiti around world therefor present work present potenti candid new spectroscop probe xe co nno conjug aminophenyl benzothiazol complex xeabt propos chemic shift calcul dft level perform thus factori design carri order choos best comput method best combin base function zora def tzvp function pbe consid relativist effect zora implement find reveal xe chemic shift affect thermal solvent effect consid enzymat environ signific decreas xe valu observ suggest xeabt complex may promis spectroscop probe

D014979;D013844

T196;T109

36,318,245

perceiv impact project echo network northern ireland health social care provid patient health system qualit analysi studi assess perceiv impact benefit project echo extens communiti healthcar outcom tele mentor intervent health social care provid patient health system northern ireland access specialist space share experi abl dissemin date best practic cite improv provid knowledg well improv qualiti care patient healthcar provid report confid manag patient relationship improv differ level health system echo describ improv access educ train remov geograph time barrier one first studi qualit analys impact across number differ clinic social care echo network result strong indic perceiv benefit echo improv provid patient health system outcom increas healthcar provid knowledg confid manag patient primari level health system implic futur servic design particular within context covid virtual onlin train necessit social distanc requir

D000086382

T047;T067

36,318,211

chang clinic workforc provid contracept abort care us cross section studi investig chang workforc provid contracept abort servic covid pandem

D003267;D005193

T061;T058;T033

36,318,210

use us food drug administr expedit drug develop review program orphan nonorphan novel drug approv us food drug administr fda program use alon combin expedit drug avail acceler approv breakthrough therapi fast track prioriti review drug use program includ novel drug contain previous fda approv activ moieti orphan drug intend diseas condit affect fewer peopl date comprehens evalu program use combin publish

D017277;D001688

T121;T123;T064

36,318,209

estim death attribut excess alcohol use among us adult age year alcohol consumpt lead prevent caus death us death rate fulli alcohol attribut caus eg alcohol liver diseas increas past decad includ among adult age year howev comprehens assess alcohol attribut death among popul includ partial alcohol attribut caus lack

D019973

T047;T048

36,318,208

associ hormon therapi depress menopaus cohort danish women menopaus level estrogen progesteron decreas women experi menopaus symptom includ mood disturb latter might prevent hormon therapi ht yet studi suggest use ht might associ increas risk depress

D015914;D011372

T061;T121;T039;T125

36,318,207

associ gonadotropin releas hormon analogu use subsequ use gender affirm hormon among transgend adolesc gonadotropin releas hormon analogu gnrha use puberti improv mental health among transgend gender divers tgd adolesc previous studi tgd adolesc start gnrha subsequ start gender affirm hormon gah rais concern gnrha use promot later use gah

D063106;D014189

T032;T098

36,318,206

perspect academ oncologist offer expand access investig drug expand access ea pathway permit patient treat investig medic product outsid clinic trial cancer care common indic ea sought effort requir physician manag understand oncologist perspect help illumin factor influenc patient access

D015507;D000072103

T121;T097

36,318,205

valid singl item screen cannabi sis c cannabi use disord screen routin care cannabi use preval increas frequent use intensifi risk cannabi use disord cud cud underrecogn medic set valid singl item cannabi screen could increas recognit

D002189;D002188;D019966

T121;T109;T002;T033;T047;T167;T048

36,318,198

neurodegener marker galectin apolipoprotein e elev aqueous humor eye glaucoma galectin gal apolipoprotein e apo marker activ microglia neurodegen diseas central nervous system whose target protect mous model glaucoma studi examin level gal apo human aqueous humor ah defin clinic associ glaucoma

D005902;D005901

T047

36,318,196

impact reticular pseudodrusen choriocapillari flow deficit choroid structur optic coher tomographi angiographi examin impact reticular pseudodrusen rpd choriocapillari blood flow choroid structur individu intermedi age relat macular degener amd

D015593;D008268

T047

36,318,195

combin aibp apoa aflibercept overcom anti vegf resist neovascular amd inhibit arteriolar choroid neovascular anti vegf resist repres major unmet clinic need manag choroid neovascular cnv previous report combin aibp apoa anti vegf antibodi overcom anti vegf resist laser induc cnv old mice prevent experi purpos work conduct clinic relev studi assess efficaci combin aibp apoa aflibercept treatment anti vegf resist experiment cnv differ time point laser photocoagul

D020256;D057135

T047;T046

36,318,192

typic viewpoint object better detect atyp one previous work claim canon viewpoint object readili perceiv noncanon viewpoint howev studi requir particip identifi object late perceptu process best arguabl cognit process pylyshyn extend work earli vision remov explicit need identifi object particular ask particip make intactscrambl discrimin briefli present object view either typic atyp viewpoint notabl particip identifi object discrimin nois scrambl particip sensit discrimin object present typic encount orient object present atyp depth rotat experi howev effect object present atyp pictur plane rotat oppos typic one reach statist signific experi suggest particular inform view may play critic role effect interpret enhanc percept item good exemplar probabl scene deriv high real world statist regular

D009949

T041

36,318,191

divid attent effect visual search caus object space divid attent effect observ across varieti stimuli perceptu task given rise object base space base theori divid attent object base theori assert process inform multipl object limit wherea space base theori assert process inform multipl locat limit extant result literatur collect inconsist simpl object base theori simpl space base theori divid attent use visual search task extend simultan sequenti method reveal capac limit found evid limit capac process object properti unlimit capac process featur contrast found evid separ spatial limit multipl pathway process theori account larg bodi previous result accord theori task requir object process must follow limit capac pathway therefor incur divid attent effect task depend featur contrast follow separ unlimit capac process pathway therefor incur divid attent effect

D001288;D013028

T041

36,318,190

achromat chromat perceiv contrast reduc visual peripheri loss contrast sensit eccentr well document steeper higher spatial frequenc lm cone oppon stimuli compar achromat cone oppon ask perceiv contrast depend eccentr stimuli present suprathreshold contrast test two oppos predict contrast constanc predict loss perceiv contrast across visual field regardless chang detect threshold appear depend physic contrast convers perceiv contrast may scale way detect threshold reflect proport increas stimulus contrast threshold measur perceiv contrast lm cone oppon cone oppon ach stimuli degre eccentr use afc contrast match method fovea peripheri test rang refer contrast low close detect threshold high suprathreshold contrast relat suprathreshold perceiv contrast measur detect threshold find evid hybrid model appar contrast reduc eccentr stimuli low mid contrast rang contrast constanc attain highest contrast equat similar sensit loss find differ chromat ach contrast respons

D015350;D017949

T025;T041

36,318,173

filariasi alcohol male coincident causal associ lymphat filariasi parasit diseas transmit mosquito carri minut thread like worm usual sign symptom seen patient diseas part peopl howev develop condit call elephantiasi mark sever swell arm leg breast genit descib interest case year old alcohol brought emerg depart alleg histori injuri incident found microfilariasi thorough blood smear screen case illustr need smear evalu diagnos microfilariasi also beg whether patient may suscept parasit infect due impair immun system

D004605

T047

36,318,172

applic artifici intellig earli comparison efficaci new cancer drug clinic choic among recent approv cancer drug burden absenc direct comparison term efficaci across new agent articl present ipdfromkm method artifici intellig ai applic aim facilit analys efficaci base secondari data

D009369;D000970

T121;T191;T109

36,318,171

psycholog take charg oncolog patient year studi activ psychologist piedmont aosta valley oncolog network tumor patholog bio psycho social event consequ person life point view physic psycholog relat social mental discomfort chronic pain neoplast patholog bring present case request help psychologist provid specif diagnost therapeut assist path case medic patholog less piedmont vall daosta oncolog network role coordin network servic deal care cancer patient includ relat psycho oncolog articl present data relat activ psycho oncologist network year

D008495;D001943

T191;T091

36,318,170

home care home venous access devic insert covid pandem autonom patient emerg activ daili work practic reliabl venous access essenti provid effect care mani patient various vascular access devic vad avail place special team use ultrasound guidanc dedic room hospit howev pandem covid mani autonom bedridden patient unabl reach hospit vad insert unavail ambul transport reason special team organ modal posit vad bedsid home

D000086382;D019636;D013927;D006699

T047;T046;T058;T067

36,318,169

palliat care lombardi region analysi care offer lombardi region one widespread advanc model palliat care pc countri howev relat lack updat data refer activ lombardi pc network

D017051;D010166

T061;T058;T093

36,318,168

conscienti object assist suicid switch rule last year legal weight sick person autonomi increas promot mani countri today legisl allow euthanasia andor assist suicid within law even though assist suicid could caus discomfort sick person often prefer order balanc right doctor respect ethic deontolog principl sick peopl put end suffer line need keep balanc deontolog rule medicin right sick peopl would appropri shift current legal framework consid physician assist suicid oblig doctor conscienti object except anoth envisag physician assist suicid oblig doctor consid conscienti willing except

D017236;D005065;D010820

T058;T097;T054

36,318,167

medic assist die itali bill law polit compromis two judgement italian constitut court first one relat decriminalis well defin condit articl penal code support incit commit suicid second relat referendum held regard partial repeal articl penal code murder consent parti issu physician assist suicid pas recent regul bill law approv italian chamber deputi current senat regist

D010817;D017236

T054

36,318,166

effect effici time come differ attitud health profession health system administr toward effici effect reveal inner health system tension logic produc care tension entail risk dire consequ universalist health protect system push toward dissoci care relationship privat safeguard constraint effici form access inequ generat howev effici product health mean cut qualiti care qualiti oper choic ask clinician evid base medicin administr balanc sheet valu health result health servic health system effect serv scope must administ effect treatment peopl condit benefit

D001290

T078;T055;T041

36,318,156

molecular mechan claudin strand flexibl comput studi claudin one major compon tight junction play key role format mainten epitheli barrier function tight junction strand dynam capabl adapt structur respons larg scale tissu rearrang cellular movement present molecular dynam simul claudin strand nm length two parallel lipid membran character mechan properti persist length claudin strand compar obtain analys freez fractur electron microscopi result indic later flexibl claudin strand due interplay three set interfaci interact network two antiparallel doubl row claudin membran model claudin assembl interlock tetramer ion channel along strand slide respect strand curv submicromet length scale result suggest novel molecular mechan under claudin strand flexibl also shed light intermolecular interact role maintain epitheli barrier function

D057167;D019108

T123;T116;T030

36,318,155

reconstitut depolar induc ca releas platform valid skelet muscl diseas mutat drug discoveri skelet muscl excit contract e c coupl depolar plasma membran trigger ca releas sarcoplasm reticulum sr refer depolar induc ca releas dicr dicr occur type ryanodin receptor ryr physic interact dihydropyridin receptor cav subunit specif machineri form addit essenti compon includ stac adaptor protein junctophilin exom sequenc acceler discoveri mani novel mutat gene encod dicr machineri various skelet muscl diseas howev function valid time consum must perform skelet muscl environ studi establish platform reconstitut dicr hek cell essenti compon effect transduc hek cell express ryr use baculovirus vector ca releas quantit measur r cepiaer fluoresc er ca indic without contamin extracellular ca influx cell k depend ca releas trigger chemic depolar aid inward rectifi potassium channel indic success reconstitut dicr use platform evalu sever cav mutat implic malign hyperthermia myopathi also test sever ryr inhibitor wherea dantrolen cpd inhibit dicr procain effect furthermor twitch potenti perchlor thiocyan shift voltag depend dicr negat potenti without affect ca induc ca releas result well reproduc find muscl fiber cultur myotub sinc procedur simpl reproduc reconstitut dicr platform high use valid mutat drug discoveri skelet muscl diseas

D019837;D009135

T047;T116;T192

36,318,154

conform defin rexinoid prevent inflamm nonmelanoma skin cancer compound potent rexinoid high effect cancer chemoprevent elev serum triglycerid effort separ lipid toxic anticanc activ synthes four new analog rexinoid three rexinoid elev serum triglycerid rexinoid twice potent rexinoid bind retinoid x receptor rxr tran retino acid atra play key role maintain skin homeostasi rexinoid high effect upregul gene respons biosynthesi atra inflamm play key role skin cancer rexinoid high effect diminish lps induc inflamm rexinoid high effect prevent uvb induc nonmelanoma skin cancer nmsc without display overt toxic biophys studi rexinoid bound hrxr ligand bind domain lbd reveal import conform dynam differ ligand bind domain

D013764;D012878

T191;T109

36,318,140

advers matern deliveri outcom children young age year us adolesc compar older adolesc adult studi use us claim databas compar morbid deliveri outcom among pregnant year old vs year old year old

D008423;D011253;D011256;D011248

T033;T040;T079;T046

36,318,139

request self manag medic abort provid use onlin telemedicin us state dobb v jackson women health organ decis studi assess chang onlin telemedicin request self manag abort medic vs dobb v jackson women health organ suprem court decis overturn roe v wade

D000028;D000073278;D017216;D000019;D035521

T061;T121;T039;T092;T093;T033;T089;T081;T058;T046

36,318,134

dobb decis threaten full breadth ob gyn train medic news articl discuss overturn roe v wade chang train futur obstetrician gynecologist state abort ban sever restrict

D000029;D006176;D009774;D004503;D035521;D002983

T061;T091;T080;T092;T065;T089

36,318,133

associ unintend pregnanc matern infant health outcom systemat review meta analysi unintend pregnanc common us associ advers matern infant health outcom howev estim associ specif current us popul lack

D000068104;D049168;D000068097;D011248

T033;T081;T046;T080

36,318,132

menopaus hormon therapi prevent chronic condit jama patient page summar us prevent servic task forc recommend use hormon therapi prevent chronic condit postmenopaus individu

D002908;D020249;D008593

T061;T047;T039

36,318,128

hormon therapi primari prevent chronic condit postmenopaus person updat evid report systemat review us prevent servic task forc uncertain whether hormon therapi use primari prevent chronic condit heart diseas osteoporosi type cancer

D002908;D004967;D020249;D017698;D011372

T061;T121;T039;T109;T040;T033;T125;T047

36,318,127

hormon therapi primari prevent chronic condit postmenopaus person us prevent servic task forc recommend statement menopaus defin cessat person menstrual cycl defin retrospect month final menstrual period perimenopaus menopaus transit year time period preced person final menstrual period character increas menstrual cycl length variabl period amenorrhea often symptom vasomotor dysfunct preval incid chronic diseas eg cardiovascular diseas cancer osteoporosi fractur increas age us person reach menopaus expect averag live anoth year

D002908;D004967;D017698;D011372;D020249;D006728

T039;T121;T061;T109;T040;T033;T125;T047

36,318,126

challeng emerg abort care follow dobb rule viewpoint discuss limit block access legal abort affect provis emerg critic care includ negat effect patient health legal intrus patient physician decis make process concern legal jeopardi

D000028;D004632;D006297;D035521

T061;T080;T092;T093;T033;T089;T081;T058;T046

36,318,125

interoper post roe era sustain progress protect reproduct health inform viewpoint propos solut better safeguard reproduct health inform patient record complet owe interoper health inform exchang network

D060728;D035521;D000073892

T089;T092;T058;T091

36,318,124

confront medic communiti complic margin abort care viewpoint discuss exclus abort care mani establish medic sourc hospit coverag mani major payer health care system legitim ensur clinician train safe abort care

D000028;D028661;D006297

T061;T078;T080;T093;T033;T081;T046

36,318,123

legal risk ethic dilemma clinician aftermath dobb viewpoint discuss way suprem court rule dobb v jackson women health organ trigger abort ban restrict half state present serious legal risk clinician major ethic dilemma

D000028;D010820;D035521;D006297

T061;T080;T092;T093;T033;T097;T081;T089;T046

36,318,122

shift crimin legal abort argentina viewpoint discuss passag implement law legal abort argentina certain circumst examin ongo clinic issu legal challeng law

D000028;D000024

T061;T093;T033;T081;T046

36,318,121

self manag abort us viewpoint detail clinician treat patient self manag abort without put patient risk crimin

D000028;D000073278;D012648

T061;T093;T033;T056;T081;T058;T046

36,318,120

advanc birth equiti post dobb us viewpoint discuss us suprem court decis dobb v jackson women health organ describ decis threaten birth equiti racial social group suggest reproduct justic approach address racial social inequ ensur reproduct freedom autonomi peopl

D000029;D000069576;D035521;D046269

T061;T078;T080;T092;T089

36,318,119

implic dobb decis medic educ inadequ train moral distress viewpoint discuss state restrict abort affect medic student train provid reproduct health care also creat moral distress forc provid care may harm patient

D004501;D009014;D035521

T065;T092;T089;T078

36,318,108

dissoci adsorpt water camn cation cluster water split catalyz photosystem ii compris inorgan core camn protein ligand understand evolut camn attach water molecul isol camn cluster investig use vibrat spectroscopi densiti function theori calcul comput find suggest water molecul adsorb ca atom atom water one oh bond form hydrogen bond oxo bridg dissoci two oh group consist fact isom molecular adsorb water experiment observ

D014867;D010100

T121;T197;T196;T123

36,318,069

simul dark field x ray microscopi imag wavefront propag techniqu dark field x ray microscopi diffract base synchrotron imag techniqu capabl imag defect bulk extend crystallin sampl numer simul present imag format microscop use numer integr dynam takagi taupin equat wavefront propag approach valid compar simul imag experiment data near perfect singl crystal diamond contain singl stack fault defect illumin volum

D008853;D017356

T059;T073

36,318,068

extend novel base phase algorithm solut anomal scatter substructur sad data protein crystal owe import singl wavelength anomal diffract sad techniqu recent develop base phase algorithm incorpor inner pixel preserv ipp procedur rius torrell acta cryst adapt determin anomal scatter substructur applic test seri repres experiment data set most retriev protein data bank give idea suitabl data set main indic measur qualiti also given domin anomal scatter either semet atom metalsclust incorpor soak result sad adapt algorithm solv substructur test protein crystal quit effici

D011506;D000465

T123;T170;T116

36,318,050

one session treatment compar multisess cbt children age year specif phobia aspect non inferior rct children young peopl specif phobia signific affect mental health develop daili function cognit behaviour therapi base intervent remain domin treatment limit provis warrant investig low intens altern one session treatment one altern share cognit behaviour therapi principl shorter treatment period

D015928;D000086382;D010698

T061;T047;T067;T048

36,318,008

medic biographi isak samokovlija famous bosnian herzegovinian writer purpos paper shed light biograph profession health educ work dr isak samakovlija better known writer doctor countri born born gorad easternmost provinc austrian hungarian monarchi modest jewish merchant famili attend high school sarajevo complet studi medicin vienna first world war serv twice austro hungarian armi end first world war complet medic internship nation hospit sarajevo began servic doctor first gorad fojnica sarajevo establish independ state croatia may dismiss duti servic without right pension support without right appeal independ state croatia twice mobil home guard manag clinic alipain refuge camp world war ii head health educ depart ministri public health peopl republ bosnia herzegovina sarajevo togeth group enthusiast doctor found edit first bosnian medic journal ivot zdravlj life health journal dr samokovlija publish articl health educ content dr samokovlija left ministri public health continu edit literatur art journal brazda still privat practic end life die sarajevo januari buri highest state honor jewish cemeteri sarajevo conclus isak samakovlija one first medic doctor born bosnia herzegovina made signific contribut improv peopl health first second world war place work special contribut articl health educ

D011634;D006761

T091;T093;T073

36,318,007

measur vaccin effect observ studi design herein present bird eye view common observ studi design util measur vaccin effect assess vaccin effect integr part vaccin research particular newli develop vaccin cohort studi prospect direct exposur one outcom design best method ascertain attack rate infecti diseas tradit case control studi retrospect direct given outcom one exposur design provid relat risk provid odd ratio good estim relat risk attack rate low critic depend laboratori test result perform test negat case control studi design anoth type observ studi common use nowaday evalu vaccin effect compar cohort tradit case control design conduct test negat case control studi relat cheaper faster herein describ mention studi design exampl generat mont carlo simul program assum real world condit conclus simul show regardless studi design employ diagnost test specif utmost import provid valid estim vaccin effect

D000087507;D014612

T081;T129;T121;T116

36,318,005

pseudohyponatremia secondari hypercholesterolemia set intrahepat cholestasi due metastat liver diseas case report review literatur describ rare case pseudohyponatremia set hypercholesterolemia caus cholestasi due metastat liver diseas provid review publish case literatur

D006937;D007010;D002780;D002779;D009369

T047;T191

36,318,004

text neck syndrom disentangl new epidem aim report provid brief review predispos factor text neck syndrom along diagnost therapeut approach young adult popul text neck pain worldwid public health problem larg report nowaday current data shown erron use person comput cell phone might correl develop various clinic symptom defin text neck syndrom modifi radic chang everyday life may amelior power forc cervic spine lead cervic degener along development medic psycholog social complic attribut text neck syndrom conclus new technolog potenti harm addict cell phone comput read text induc epidem text neck syndrom focus postur correct pain allevi better qualiti life achiev patient predispos factor therapeut approach syndrom affect public health remain elucid

D060145

T170;T052;T066

36,318,003

research phenomenon poor ovarian respond manag strategi ivf narrat review narrat review aim summar latest studi publish concern manag protocol adopt poor ovarian respons por case patient defin poor respond show minim respons control ovarian hyperstimul although standard definit por although infertil specialist endeavor improv cycl outcom poor respond adopt multipl manag strategi still estim risk cycl cancel studi perform studi period evalu result record latest publish protocol improv oocyt retriev poor respond includ anti mllerian hormon clomiphen citrat co enzym q corifollitropin dehydroepiandrosteron doubl stimul follicl stimul hormon growth hormon gonadotropin releas hormon agonist letrozol human chorion gonadotropin lutein hormon progesteron testosteron conclus although mani strategi suggest manag por none proven superior other larg scale random studi need valid experiment techniqu lead toward success individu treatment regimen

D010062;D054315

T061

36,318,002

comparison effect wycop video laryngoscop c mac video laryngoscop direct laryngoscop intub elect surgeri patient airway manag undergon dramat transform sinc arriv video laryngoscop vl vl higher intub success rate first tri lower complic comparison direct laryngoscop dl use vl recommend intub covid patient speed intub time reduc failur rate team airlangga univers develop wycop video laryngoscop wycop vl vl wi fi connect smartphon easier vl low cost studi aim compar effect wycop vl c mac video laryngoscop c mac vl dl

D020704;D000086382

T047;T074;T067

36,318,001

morphometr analysi supraorbit foramen notch popul bosnia herzegovina aim studi learn morpholog characterist supraorbit foramen determin precis posit relat surround anatom landmark adult popul bosnia herzegovina

D005624;D009915

T023;T030

36,318,000

partial superfici parotidectomi versus extracapsular anatom dissect treatment benign parotid tumor superfici benign parotid tumor common neoplasm salivari gland differ surgic procedur appli partial superfici parotidectomi psp extracapsular dissect ecd two predomin surgic techniqu studi aim evalu psp versus ecd benign parotid tumor relat post oper complic recurr rate

D010307

T191

36,317,999

potenti cinnamon extract cinnamomum burmanii anti insomnia medic hypothalamus pituitari adren axi improv rat studi aim explor efficaci cinnamon extract anti insomnia medic experiment anim evalu level hormon neurotransmitt relat insomnia

D007319;D027424

T184;T047;T002;T048

36,317,998

evalu sar cov antibodi respons post third dose covid mrna vaccin universita indonesia hospit longev vaccin effect antibodi titer moderna mrna covid vaccin booster healthcar worker indonesia known

D000917;D000086382

T047;T067;T038

36,317,995

role circular rnas multipl sclerosi neuroimmun disord recent year non code rnas receiv increas attent import epigenet mechan particular role micro rnas regul mirna express high dynam complex grow evid suggest exist anoth higher level regulatori mechan involv mirna activ circular rnas circrna circrna repres novel uniqu class endogen ncrnas control express function mirna call natur mirna spong accumul evid reveal circrna role physiolog patholog process includ cns immun regul previous studi implic mirna regul autoimmun demyelin ms multipl sclerosi chronic neurolog inflammatori demyelin disord central nervous system etiolog ms still fulli understood accumul evid suggest multifactori entiti signific involv autoimmun process

D009103;D035683;D009422

T123;T047;T114

36,317,994

role mcpip protein lipid metabol liver homeostasi non alcohol fatti liver diseas non alcohol fatti liver diseas nafld character excess accumul lipid hepatocyt among nafld patient diseas progress nonalcohol steatohepat character addit develop inflamm fibrosi liver current estim world popul suffer nafld mcpip protein rnase describ negat regul inflamm also mcpip play role lipid metabol inhibit process adipogenesi mice delet zcha gene character dyslipidemia reduc bodi fat content case ischemia reperfus injuri liver mcpip protect inflamm damag organ lipid accumul hepatocyt associ decreas mcpip level addit mcpip may influenc ppar mediat lipogenesi process presenc mcpip myeloid leukocyt liver epitheli cell crucial mainten liver homeostasi

D065626

T047

36,317,993

stimul effect metal biosynthesi plant bioactiv compound secondari metabolit produc plant rich group bioactiv compound mani health promot properti use various sector industri includ pharmaceut cosmet industri one problem applic plant deriv compound low level plant tissu thus new method aim stimul biosynthesi plant metabolit investig recent year sever articl use metal elicitor publish present review present exampl applic copper cu zin zn cadmium cd select nanoparticl elicitor

D015032;D002104

T123;T196;T121;T131

36,317,992

dna base predict human phenotyp trait medico legal forens purpos studi aim present current state knowledg dna base predict human extern visibl characterist unknown person base crime scene biolog materi left behind dna sampl refer biolog wit procedur call forens dna phenotyp fdp analyt part work base scholar articl publish electron search relev refer conduct accord prisma methodolog march ebsco discoveri servic ed adam mickiewicz univers librari googl scholar molecular basi fdp dna marker use predict sex age biogeograph origin extern visibl trait pigment skin eye hair colour hair morpholog facial morpholog presenc freckl bodi height bodi weight obes male pattern bald myopia describ furthermor methodolog difficulti result polygen inherit studi trait well social ethic problem accompani forens dna phenotyp discuss final key theme futur research relat forens dna phenotyp outlin

D005127;D053803

T032;T091

36,317,991

argonaut protein cell biolog plant develop argonaut ago protein integr part regulatori pathway control small rna srna fundament proper function eukaryot cell ago high special platform bind specif srna coordin gene silenc interact protein factor form rna induc silenc complex risc contribut endonucleolyt cleavag target mrna andor influenc translat process increas number evid confirm particip ago protein sever cellular process ie transcript regul sequestr rna depend methyl dna repair dna damag synthesi sirna independ dcl dicer like protein co transcript regul mirna gene express intron splice particular plant speci character presenc differ number ago protein mani case yet unknown regulatori andor biolog function review articl cover current knowledg function ago cell biolog plant develop

D060565;D035683

T123;T116;T114

36,317,990

pharmacolog chaperon therapi treatment inborn error metabol articl describ mechan molecular pharmacolog chaperon treatment inborn error metabol literatur review usag ambroxol act pharmacolog chaperon beta glucocerebrosidas gaucher diseas parkinson diseas associ gba variant review

D005776;D000551;D010300

T121;T047;T109

36,317,989

crisprca intellig immun system bacteria archea invent crispr consid one breakthrough discoveri recent year histori biolog biotechnolog medicin well pharmaceut agricultur industri method develop use crispr creat new previous unattain possibl signific improv qualiti life invent intellig immun system present day much research done use crisprca system result studi develop modern tool genet manipul allow introduct mani modif within dna may contribut silenc express given gene overexpress eg mutat delet paper describ applic method genet manipul use second class system crisprca advantag method advantag previous use genet engin tool well limit disadvantag signific limit possibl applic potenti use method also present well research carri use crsprcas

D064113;D000072669

T063;T040

36,317,988

parent age assist reproduct technolog analysi risk chronic diseas progeni concept child advanc parent age year steadili increas recent decad especi develop countri socio econom factor effect contracept avail assist reproduct technolog art direct impact postpon decis babi art enabl reproduct success peopl diagnos infertil reduc possibl becom pregnant due concomit patholog epidemiolog studi indic advanc parent age art associ patholog pregnanc gestat diabet risk pre eclampsia miscarriag placent abrupt preterm labor stillbirth neurodevelopment disord chronic diseas offspr work focus avail inform metabol chang increas risk develop cardiovascular diseas offspr parent advanc age conceiv art final address sourc observ disturb gamet embryo level relat oxygen stress epigenet modif dna damag consid possibl rescu action

D047928

T046

36,317,987

molecular mechan progesteron action femal reproduct system progesteron p steroid hormon particip mani process femal reproduct system hormon produc main corpus luteum cl howev also ovarian follicl uterin tissu placenta abl produc p progesteron involv regul sexual cycl well initi mainten pregnanc hormon may affect cell function genom mechan nuclear p receptor pgr via nongenom mechan membran p receptor progesteron receptor membran compon pgrmc membran progestin receptor mpr genom mechan p action lead express target gene synthesi new protein nongenom mechan modifi various intracellular signal pathway integr two mechan p activ lead suitabl regul cell tissu consequ respons organ hormon

D011374;D011980

T123;T121;T116;T109;T192;T125

36,317,986

soft laser applic area oral surgeri stomatolog low level laser lll use stomatolog oral surgeri field dentistri due biostimul biomodul photodynam effect heal process soft tissu bone wound acceler indic oral surgeri achiev faster bone heal tooth extract also improv osseointegr implant advantag stomatolog pain allevi improv heal aphtha cold sore well symptom relief mucos due use free side effect low time effort lll offer high patient comfort

D019242

T091

36,317,981

covid mortal usual occup industri state new york citi unit state object report describ covid mortal among us resid state new york citi usual occup industri

D000086382

T047;T067

36,317,979

target neonat echocardiographi patient hemodynam instabl target neonat echocardiographi tne increas use bedsid neonat care provid enhanc understand physiolog affect manag hemodynam unstabl patient tradit method bedsid assess includ blood pressur heart rate monitor capillari refil unabl provid complet pictur tissu perfus oxygen tne allow precis medicin provid tool identifi pathophysiolog continu reassess rapid chang hemodynam relationship cardiolog integr train well qualiti assur imper congenit heart diseas rule util tne hemodynam manag pathophysiolog vari substanti assess manag patient congenit heart diseas util tne longitudin hemodynam assess requir extens train field continu grow guidelin protocol train indic essenti ensur optim use provid platform qualiti assur

D006330;D014652

T019;T047

36,317,978

analgesia sedat anesthesia neonat cardiac diseas analgesia sedat anesthesia continuum diagnost andor therapeut procedur newborn often requir analgesia sedat andor anesthesia newborn general particular heart diseas increas risk serious advers event includ mortal anesthesia section discuss assess manag pain discomfort intervent review dose side effect common use medic provid recommend use newborn heart diseas procedur requir deeper level sedat anesthesia airway hemodynam support might necessari although associ long term deleteri neurocognit effect anesthet agent receiv consider attent scientif lay press causal establish nonetheless earli multimod multidisciplinari approach benefici safe manag intervent procedur surgeri avoid problem toler delirium contribut long term cognit dysfunct

D000698;D000758;D006331

T061;T047

36,317,976

care fetus congenit cardiovascular diseas diagnosi deliveri major congenit cardiovascular diseas includ structur cardiac defect abnorm cardiac function rhythm disturb identifi prenat use screen obstetr ultrasound referr fetal echocardiogram indic

D002318;D006330

T019;T047

36,317,975

preoper manag neonat congenit heart diseas clinician care neonat congenit heart diseas encount challeng clinic care infant await surgeri evalu potenti intervent newborn heart diseas present signific pathophysiolog heterogen therefor requir person therapeut manag plan howev complex field neonat cardiac hemodynam simplifi explor clinic quandari includ specif section review anatom challeng patient propos serv primer focus hemodynam therapeut strategi preoper neonat systol dysfunct diastol dysfunct excess pulmonari blood flow obstruct pulmonari blood flow obstruct system blood flow transposit physiolog singl ventricl physiolog

D006330

T019

36,317,974

bioethic neonat cardiac care clinician care neonat congenit heart diseas encount challeng ethic implic daili practic must basic fluenci ethic principl practic applic

D001675

T091

36,317,973

evalu manag noncardiac comorbid children congenit heart diseas outcom patient neonat heart diseas affect numer noncardiac genet factor includ neonat concern prematur low birth weight congenit anomali airway pulmonari gastrointestin genitourinari anomali genet syndrom section serv summari issu may affect evalu manag neonat heart diseas noncardiac factor heavili influenc condit common neonatologist make strong argument multidisciplinari care neonatologist cardiologist surgeon anesthesiologist cardiovascular intensivist section project aim facilit comprehens approach care neonat congenit heart diseas

D006330;D007235

T019;T047

36,317,972

nutrit consider neonat congenit heart diseas import nutrit manag critic ill infant congenit heart diseas chd foundat optim short long term health outcom growth failur malnutrit common infant chd etiolog growth failur popul often multifactori may relat alter metabol demand compromis blood flow intestin lead nutrient malabsorpt cellular hypoxia inadequ energi intak poor oral motor skill dearth high qualiti studi gap previous publish guidelin led wide variabl nutrit practic local driven review provid recommend nutrit subgroup neonat cardiac care collabor best evid base practic provis nutrit support infant chd review evid recommend focus predefin area clinic care target popul infant month chd admit icu inpati ward area includ energi need nutrient requir enter nutrit feed practic parenter nutrit outcom futur progress direct qualiti improv effort optim periop nutrit manag increas emphasi individu care base nutrit status cardiorespiratori physiolog state ill vulner

D004750;D006330

T061;T019;T074

36,317,971

acut cardiac care neonat heart diseas manuscript one compon larger seri articl produc neonat cardiac care collabor publish supplement pediatr review articl summar contemporari physiolog principl evalu manag acut care issu neonat complex congenit heart diseas multidisciplinari team author creat collabor execut committe author develop detail outlin manuscript small team author assign draft specif section author review literatur focus origin manuscript publish last decad draft preliminari content recommend author subsequ review edit entir manuscript consensus achiev topic address includ cardiopulmonari interact pathophysiolog strategi minim develop ventil induc low cardiac output syndrom common postop physiolog periop bleed coagul common postop complic

D002303;D003422

T033;T058;T046

36,317,967

optim neurodevelopment outcom neonat congenit heart diseas neurodevelopment impair common import long term morbid among infant congenit heart diseas chd half complex chd demonstr form neurodevelopment neurocognit andor psychosoci dysfunct requir special care impact long term qualiti life prevent brain injuri treat long term neurolog sequela high risk clinic popul imper improv neurodevelopment psychosoci outcom thus cardiac neurodevelopment care forefront clinic research effort initi research primarili focus neurocrit care oper strategi mitig brain injuri field evolv investig shift understand prenat genet environment contribut impair neurodevelop articl summar recent literatur detail brain abnorm affect neurodevelop children chd impact genet neurodevelopment outcom best practic neonat neurocrit care focus development care parent support new area import framework also provid infrastructur resourc need support chd famili across continuum care set

D006330;D065886;D001930

T019;T037;T048

36,317,960

sustain dentistri part ii sustain workplac wast manag second final part public topic sustain dental practic deal call workplac manag describ work process consumpt energi materi practic wast manag also address discuss path resourc practic dispos recycl final exampl materi research present use implant

D017132;D018505

T068;T082

36,317,936

transform evalu agrochem present agrochem safeti evalu paradigm long stand anchor well establish test evalu procedur howev meet present day challeng rapid grow popul food insecur pressur climat chang transform current framework appli modern evalu strategi better support sustain agricultur health environment scienc institut hesi assembl technic committe refram safeti evalu crop protect product committe compos intern expert regulatori agenc academia industri nongovernment organ mission establish framework support develop fit purpos agrochem safeti evalu applic chang global well local need regulatori decis incorpor relev evolv scienc accomplish integr state art scientif method technolog data sourc inform safeti risk decis adapt evolv local global need project team use system think approach develop tool implement problem formul exposur driven approach creat sustain safe effect crop protect product reduc replac refin anim studi fit purpos assay new approach necessarili integr modern tool latest advanc chemic test method guarante robust human environment safeti risk assess agrochem articl summar challeng associ modern agrochem safeti evalu propos potenti roadmap seek input engag broader communiti advanc effort health environment scienc institut hesi pest manag scienc publish john wiley son ltd behalf societi chemic industri

D016573;D000069601

T120;T057

36,317,919

efficaci nitrit therapi treatment heart failur meta analysi random control trial efficaci nitrit therapi treatment heart failur remain controversi conduct systemat review meta analysi explor impact nitrit therapi heart failur

D006333;D012749

T047;T046

36,317,918

surgeri fate patient lerich syndrom endovascular therapi result earli follow outcom research aim present earli follow result endovascular treatment patient lerich syndrom singl center

D007925;D019917;D057510

T061;T047

36,317,917

earli clinic outcom thoracoscop mitral valvuloplasti first case report case thoracoscop mitral valvuloplasti earli stage sought analyz earli clinic outcom

D008944;D006348

T061;T047

36,317,916

summari experi result transesophag ultrasound guid ventricular septal defect atrial septal defect closur oper ventricular septal defect vsd atrial septal defect asd congenit heart diseas techniqu transthorac closur tc percutan closur pc treatment vsd asd continu improv matur studi aim retrospect analyz therapeut effect tc pc vsd asd patient

D006345;D006344

T019

36,317,915

embol aortopulmonari collater arteri cooper valv conduit attach right ventricular outflow tract patient tetralog fallot repair one stop procedur describ one stop procedur aortopulmonari collater arteri apca postop complic tetralog fallot tof postop complic tof includ right ventricular outflow tract stenosi pulmonari valvular annular stenosi pulmonari regurgit aortopulmonari arteri stenosi one stop procedur defin apca embol heart continu function cardiopulmonari bypass median sternotomi reconstruct right ventricular outflow tract valv conduit replac aortopulmonari arteri biolog valv sew within valv conduit artifici blood vessel vitro subsequ use procedur achiev signific result

D013771

T019

36,317,914

applic high frequenc oscil ventil combin volum guarante preterm infant acut hypox respiratori failur patent ductus arteriosus ligat studi aim evalu efficaci safeti high frequenc oscil ventil combin volum guarante hfov vg preterm infant acut hypoxem respiratori failur ahrf patent ductus arteriosus ligat

D004374;D012127;D006612;D012128;D012131

T061;T019;T047;T046

36,317,913

case stanford type acut aortic dissect preoper extens cerebr infarct success treat surgic patient organ malperfus acut aortic dissect aad poor outcom surgic indic patient aad complic extens cerebr infarct establish report success treat surgic case patient cerebr infarct stanford type aad year old man admit hospit chief complaint left paresi confirm cerebr hemorrhag head comput tomographi incis right neck right intern carotid arteri ligat close emerg surgeri perform mm triplex raft ascend aorta replac bypass perform prosthet graft right axillari arteri cerebr hemorrhag neurolog issu observ postop indic possibl surgic intervent treatment strategi diseas

D000784;D019917

T061;T047;T046