PMID
int64 35.7M
36.4M
| Title/Abstract
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36,315,094
|
compar studi uvh uvpm process treat pulp paper wastewat pulp paper wastewat ppww contain numer refractori harm contamin requir advanc treatment meet discharg criteria studi compar efficaci two ppww treatment ultravioletperoxymonosulf uvpm ultravioleth uvh work similar circumst initi ph valu oxid dosag uv radiat intens pseudo first order constant k ob systemat studi system optim uvpm process produc effluent higher qualiti uvh measur remov effici chemic oxygen demand cod min respect uvh uvpm process correspond k ob valu min respect radic scaveng experi demonstr oh primari reactiv oxygen speci uvh process oh uvpm process moreov ultraviolet visibl spectroscopi gas chromatographi coupl mass spectroscopi analys show deep treatment petroleum hydrocarbon carbon chain length greater macromolecular semi volatil organ compound paper wastewat difficult wherea uvpm process signific improv remov amid ester phenol aromat compound
|
D062065;D014874
|
T131;T083;T069
|
36,315,093
|
interact tio nanoparticl c vulgari oxid stress lipid peroxid lipid amount nanoparticl wide use mani industri food cosmet increas use spread environment environ also increas microalga import place uptak nanoparticl food chain studi effect tio nanoparticl antioxid enzym activ malondialdehyd hydrogen peroxid chlorophyl total lipid amount c vulgari microalga investig result dose studi superoxid dismutas ascorb peroxidas enzym activ decreas amount mda h chlorophyl increas depend time differ light dark ratio increas decreas occur sod apx enzym activ amount mda h increas amount chlorophyl time studi sod apx enzym activ increas amount mda h decreas amount chlorophyl increas total lipid studi total lipid amount group nano tio increas compar control group time c linol acid found fatti acid methyl ester group
|
D053758;D058086
|
T073;T204
|
36,315,092
|
sustain replac edta biojarosit commerci iron fenton uv fenton degrad rhowedamin b process optim use box behnken method biojarosit replac commerci iron catalyst oxid degrad dye rhodamin b confirm establish investig oxid degrad fenton oxid uv fenton oxid edta neutral ph conduct degrad target compound evalu uv fenton oxid shown effici fenton oxid degrad rhodamin b remov effici design experi perform box behnken design investig conduct predict valu separ fenton oxid uv fenton oxid rhodamin b remov taken respons variabl paramet biojarosit h dosag edta optim rang gl mm mm respect quadrat regress model fit fenton uv fenton oxid analysi varianc anova perform model fit discuss
|
D007501;D006861
|
T123;T121;T196;T197;T130
|
36,315,091
|
quantit assess optim bi function membran remedi cr vi wastewat paper explor innov approach use green rout synthes cost effect bi function elimin toxic hexaval chromium common found tanneri wastewat use integr applic membran photocatalyst contamin wastewat first pass bi function ultrafiltr membran retain hexaval chromium reduc toxic reject water high concentr cr vi photocatalyt reduct cr iii presenc sunlight use membran photocatalyst film condit govern separ process solut ph nanoparticl load polym matrix concentr cr vi optim maxim reject photocatalyt reduct cr iii purpos work optim process condit use respons surfac method rsm govern process rsm analysi conclud excel reject reduct possibl predict ph particl load cr vi concentr mgl
|
D018508;D014874
|
T131;T052;T057
|
36,315,090
|
scale photoreactor tio thin layer wastewat treatment studi devot scale potenti tio uv photocatalyst real wastewat treatment includ durabl test activ prepar tio layer first test laboratori reactor key repres pollut diclofenac chloramphenicol triclosan special pilot plant reactor two tube system stainless steel annulet cover tio thin layer inner volum l construct pilot test perform wastewat pharmaceut industri contain danazol norethisteron concentr vari mg l flow l h municip wastewat output sewag plant inhabit contain bisphenol nonyphenol estron ethinylestradiol triclosan concentr individu contamin vari ng l flow l h treatment pilot photocatalyt test concentr individu contamin decreas decreas effici photocatalyt process record long term test last month
|
D014260;D014874;D018508
|
T121;T109;T131;T052;T057
|
36,315,089
|
surfact modifi wast ash remov chloro nitro group substitut benzen wastewat surfact modifi coal fli ash develop multifunct adsorb remov organ pollut wastewat sodium dodecyl sulfat sds use modifi surfac coal fli ash cfa modifi cfa character use scan electron microscopi sem surfac poros analyz thermogravimetr analysi tga fourier transform infrar ftir spectroscopi result show load cfa sds improv function surfac morpholog raw ash adsorpt organ pollut also enhanc thermal stabil effici modifi fli ash test term remov two non polar organ pollut name chlorobenzen cb nitrobenzen nb aqueous phase maximum uptak capac chlorobenzen nitrobenzen sds modifi coal fli ash scfa mgg mgg respect kinet analysi done control kinet model ie pseudo first second order kinet model result show adsorpt cb nb onto scfa follow pseudo second order kinet model adsorpt chlorobenzen exotherm modifi adsorb nitrobenzen show endotherm behavior isotherm analysi depict multilay adsorpt pollut onto surfac surfact modifi adsorb work shown surfac modif use surfact viabl option enhanc adsorpt capac fli ash pollut remov
|
D014874;D004785
|
T131
|
36,315,088
|
mechanochem treatment degrad ciprofloxacin cip solut ciprofloxacin cip kind wide use fluoroquinolon antibiot widespread presenc cip aquat environ becom serious issu mechanochem treatment mct effect approach degrad persist organ pollut mani advantag low cost simplic environment innocu howev littl attent paid employ mct treat effluent contain cip studi mct introduc degrad cip aquat solut seri cip degrad experi conduct planetari ball mill influenc main paramet cip degrad effici investig furthermor optimum combin select orthogon experi cip degrad effici could reach high certain condit besid biotox cip solut also studi mct exhibit satisfi perform degrad cip solut make mct promis approach cip elimin also encourag applic treat effluent contain organ pollut
|
D004785;D014874
|
T131
|
36,315,087
|
remov persist organ pollut disinfect pathogen secondari treat municip wastewat use advanc oxid process afford sustain tertiari treatment imper solv secondari contamin issu relat wastewat reus decontamin disinfect actual secondari treat wastewat various type advanc oxid process aop studi optim oxid catalyst carri identifi best perform system select experiment condit uvperoxymonosulf pms pms uvmno mno uvo h mno h uvmno h uvo mno identifi effici treatment option simultan decontamin cod remov disinfect inactiv total viabl count bacteria techno econom assess reveal uvmno kg cod uvo mno kg cod uvh mno kg cod mno h kg cod compar low cost treatment process overal uvmno uvh mno mno h three best treatment nevertheless investig product catalyst toxicityrecoveri need result show aop technolog feasibl treatment simultan remov persist organ pollut pathogen secondari treat wastewat
|
D018508;D010126;D014874
|
T131;T052;T103;T057
|
36,315,086
|
advanc ahl mediat quorum sens system wastewat biolog nitrogen remov mechan function applic biolog nitrogen remov process convert organ nitrogen ammonia nitrogen nitrogen via seri reaction microorgan wide use wastewat treatment costless high effect secondari pollut free characterist quorum sens qs communic mode microorgan regul bacteria physiolog behavior respons environment chang n acyl homoserin lacton ahl mediat qs system widespread nitrogen remov relat function bacteria promot biolog nitrogen remov perform regul bacteria behavior recent increas investig ahl mediat qs system wastewat biolog nitrogen remov process consequ ahl mediat qs system consid promis regulatori strategi biolog nitrogen remov process articl review qs mechan various nitrogen remov relat function bacteria analyz effect biolog nitrogen remov perform combin applic research qs system enhanc biolog nitrogen remov put forward prospect suggest practic signific practic applic
|
D054742;D053038
|
T043;T109
|
36,315,085
|
insight activ sludgechlorella consortia dark condit compar light condit bacteria alga consortia light bring benefit product co reduct wastewat treatment bottleneck applic behav dark studi inoculum ratio sludg retent time srt affect nutrient remov rather chemic oxygen demand cod remov dark condit sludgechlorella inoculum ratio srt achiev compar perform light condit due bacteria contribut mechan aerat compar light condit ratio chlachlb decreas caro chla chlb increas respons oxid stress dark alga associ nitrosomona dechloromona flavobacterium disassoci chlorella dark associ chlorella light moreov nitrit gene amo hao denitrifi gene narh regul p metabol gene ppx ppk regul propos enrich nitrosomona night denitrifi polyphosph accumul organ dpao daytim establish short cut nitrif denitrifi phosphorus remov practic applic
|
D012722;D002708
|
T069;T002
|
36,315,084
|
recov nutrient reject trace organ compound human urin forward osmosi membran distil fo md hybrid system urin major sourc reclaim water fertil urin treatment involv two key process recoveri nutrient reject trace organ compound torc studi investig reject torc recoveri nutrient human urin use seawat driven forward osmosi membran distil fo md hybrid system three h experi conduct draw solut temperatur c averag reject rate cation anion dissolv organ carbon fo md system fo side respect ten type torc detect feed solut wherea none detect product water indic torc complet reject precipit ie recov nutrient fo side extrem close magnesium ammonium phosphat struvit mgnh po h accord electron microscop imag element composit x ray diffract spectra estim approxim nutrient feed solut recov reject recoveri effici unaffect draw solut temperatur result indic potenti sustain use fo md base treatment human urin
|
D057168;D018508
|
T057;T059;T052
|
36,315,083
|
design methodolog determin optim stage membran aerat biofilm reactor mainstream treatment anammox partial nitrit anammox pna membran aerat biofilm reactor mabr use mainstream nitrogen remov help facil reduc energi consumpt previous pna mabr research investig impact stage ie array mabr seri nitrogen remov perform oper abil suppress nitrit oxid bacteria paper mathemat model simul pna mabr perform differ influent total ammonia concentr load design methodolog stage pna mabr creat found amount membran surfac area depend upon total ammonia nitrogen concentr load air load membran must proport total ammonia nitrogen load maxim total inorgan nitrogen tin remov rate led approxim equal size stage tin remov percentag influent total ammonia nitrogen stage treatment train result larger total ammonia larger total nitrogen remov rate compar un stage reactor un stage reactor also abl produc effluent total ammonia concentr mg nl would necessari mani facil permit
|
D000641;D019149
|
T121;T197;T074
|
36,315,082
|
promot azo dye decomposit natur molybdenit activ peroxymonosulf process low concentr ferrous ion studi low concentr ferrous ion fe ad natur molybdenit mdn activ peroxymonosulf pms process degrad typic azo dye orang g og found addit fe promot og degrad simultan reduc leach toxic mo ion signific util effici mdn improv immens estim reus experi mdn main act reduct promot cycl fe fe redox coupl reduc sulfur mo iv surfac sulfat radic hydroxyl radic oh singlet oxygen verifi main reactiv oxygen speci respons og degrad scaveng test electron paramagnet reson experi paramet mdn dosag fe concentr pms concentr initi solut ph coexist anion affect og degrad effici word work provid new method enhanc pms activ mdn use low concentr fe degrad organ pollut water
|
D014874
|
T131
|
36,315,081
|
enhanc abil two kind oil degrad bacteria treat oili sludg optimis growth condit use respons surfac methodolog biosurfact surfact produc certain microorgan biosurfact increas biodegrad insolubl pollut studi ferment product pseudomona stutzeri lh ps rhodococcus sp pr rd studi oil spread method emulsifi activ infrar spectrum analysi prove ferment product biosurfact ferment condit ps rd optimis placket burman pb design hill climb experi respons surfac methodolog rsm n sourc liquid load signific factor ferment ps c sourc speed signific factor ferment rd surfac tension found low mnm ferment condit ps n sourc g liquid load surfac tension mnm incub condit rd c sourc g rotat speed rmin final experiment result degrad oili sludg show degrad rate oili sludg improv ferment condit optimis result infrar spectroscopi analysi show organ matter content oili sludg treat ps bacteria signific reduc optimis ferment studi provid theoret refer use bacteria produc biosurfact treat organ matter
|
D012722;D001419
|
T007;T069
|
36,315,074
|
nickel catalyz enantioselect reduct conjug aryl heteroaryl via elementari mechan addit nickel complex isoquinox promot enantioselect conjug aryl heteroaryl enon use aryl heteroaryl halid direct reaction success appli stereoselect synthes ar turmeron chiral fragment tolterodin azd mechanist experi calcul support arylnickel complex insert enon via elementari addit
|
D009532
|
T123;T196
|
36,315,071
|
bovin pericardi patch repair abdomin aortic pseudoaneurysm preserv lumbar arteri describ case aortic repair use bovin pericardium pseudoaneurysm dissect abdomin aorta year old man undergon sever aortic replac surgeri type b aortic dissect develop paraparesi thoraco abdomin aortic surgeri recov year schedul comput tomographi scan show pseudoaneurysm dissect abdomin aorta high risk spinal cord ischaemia aortic repair use bovin pericardium perform lumbar arteri preserv month follow asymptomat comput tomographi scan show dilat aorta
|
D017545;D017541;D000784
|
T047;T046
|
36,315,062
|
ultralight superelast gd bi nanofibr aerogel nacr mimet brick mortar structur superior x ray shield widespread use x ray prompt surg demand effect wearabl shield materi howev pb contain materi current use shield x ray common bulki hard biotox sever limit applic wearabl scenario inspir nacr report ultralight superelast nontox x ray shield nanofibr aerogel microarch engin brickmortar structur combin polyurethanebi nanofib brick gd nanosheet mortar synergist attenu effect toward x ray reflect microarch absorpt bigd element signific enhanc shield effici aerogel microarchesrobust nanofibr network endow materi superelast result materi exhibit integr properti superior x ray shield effici ultralow densiti mg cm larg stretchabl revers elong high water vapor permeabl kg day fabric novel aerogel pave way develop next generat effect wearabl x ray shield materi
|
D060734;D057139
|
T073;T109
|
36,315,050
|
p kinas mediat nlrp inflammasom activ ribotox stress respons virus infect inflammasom integr cytosol evid infect damag mount inflammatori respons inflammasom sensor nlrp express human keratinocyt coordin inflamm skin found divers stress signal induc human nlrp inflammasom assembl activ map kinas p ribotox stress respons uv microbi molecul exclus activ p mapk zak infect arthropod born alphavirus includ semliki forest chikungunya virus activ p zak potenti mapk demonstr p direct phosphoryl nlrp serin linker region critic activ nlrp phosphoryl follow ubiquitin nlrppyd n termin degrad nlrp nucleat inflammasom nlrpupa card contrast activ nlrp nanobodi mediat ubiquitin viral proteas inhibit dpp independ p activ taken togeth defin p activ unifi signal hub control nlrp inflammasom activ integr varieti cellular stress signal relev skin
|
D058847;D014777;D048051
|
T123;T047;T126;T116
|
36,315,049
|
clonal lineag trace reveal mechan skew cd cell fate decis chronic infect although recent evid demonstr heterogen among cd cell chronic infect development relationship mechan under fate decis remain incomplet understood use singl cell rna tcr sequenc trace clonal expans differenti cd cell chronic lcmv infect identifi immens clonal phenotyp divers includ subset term intermedi cell trajectori analys infect model show intermedi cell aris progenitor cell bifurc termin effector exhaust subset genet ablat experi identifi type ifn drive exhaust irf depend mechan possibl ifn stimul subset bridg progenitor exhaust cell convers zeb critic generat effector cell intrigu cell clone exhibit lineag bias mechanist identifi tcr avid correl exhaust fate wherea shp select restrict low avid effector cell accumul thus work elucid novel mechan under cd cell fate determin persist infect suggest two potenti pathway lead exhaust
|
D000088562;D018414
|
T047;T025
|
36,315,037
|
mechan recoveri plug left ventricular assist devic explant myocardi recoveri occur approxim left ventricular assist devic recipi select patient possibl elect perform left ventricular assist devic explant accur myocardi function recoveri assess sever surgic approach techniqu report literatur focus left ventricular assist devic remov preserv left ventricular geometri provid detail step step tutori continu flow left ventricular assist devic explant facilit use manufactur titanium apic recoveri plug
|
D006353;D006333
|
T047;T074;T046
|
36,315,029
|
non biolog steroid spare therapi non infecti intermedi posterior panuv adult non infecti intermedi posterior panuv niippu repres heterogen collect autoimmun inflammatori disord isol concentr posterior structur eye niippu typic chronic condit peopl niippu frequent requir treatment steroid spare immunosuppress therapi methotrex mycophenol cyclosporin azathioprin tacrolimus non biolog diseas modifi antirheumat drug dmard use treat peopl niippu
|
D008269;D015864;D018501
|
T121;T047
|
36,315,027
|
effect supplement nannochloropsi oculata microalga biochem inflammatori antioxid respons diabet rat diabet accompani inflamm oxid supplement anti inflammatori antioxid compound prevent progress diabet studi aim investig effect supplement nannochloropsi oculata microalga nom inflammatori antioxid respons diabet rat sixti male rat divid six group diabet non diabet rat receiv mgkg bodi weight nom daili day bodi weight serum concentr insulin glucos tissu concentr interleukin il tumor necrosi factor alpha tnf nuclear factor kappa b nf b interleukin il malondialdehyd mda ferric reduc antioxid power frap superoxid dismutas sod glutathion peroxidas gpx assess result show induct diabet signific reduc bodi weight serum concentr insulin tissu concentr sod frap gpx increas concentr glucos mda il il nf b tnf daili oral administr nom mgkg signific maintain bodi weight serum concentr insulin tissu concentr sod frap gpx prevent increas concentr glucos mda il tnf conclus diabet caus inflamm oxid nom work natur anti inflammatori antioxid compound
|
D058086;D003920;D061385
|
T121;T047;T204
|
36,315,022
|
aptam protein structur guid silico experiment discoveri aptam short peptid recognit complex aptam amino acid cluster complex method comput experiment identifi aptam short peptid amino acid cluster introduc method involv select well defin protein aptam complex extract peptid sequenc particip bind protein aptam subsequ fragment peptid sequenc short peptid silico dock guid identif affin complex miniatur peptid antiprotein aptam follow experiment valid bind featur short peptid antiprotein aptam lead identif new short peptid aptam complex exemplifi identif pentapeptid ryern scaffold bind thrombin dna thrombin aptam dna ta silico dock studi follow microscal thermophoresi mst experi demonstr miniatur tripeptid rye yer ern reveal select bind affin toward dna ta addit dock mst experi show ribonucleotid translat rna ta show relat bind affin yer dna ta import demonstr separ amino acid yer assembl three amino acid cluster dna ta rna ta aptam spatial configur similar tripeptid yer respect aptam cluster phenomenon select yer tripeptid system method identifi bind affin miniatur peptid known antiprotein aptam specif cluster singl amino acid aptam demonstr silico experiment identif bind tripeptid ret select cluster separ amino acid ret onto deriv aptam nucleolin receptor protein
|
D000596;D052157
|
T123;T121;T116;T114
|
36,315,013
|
central scaffold protein cep coordin centriol length stabil matur centriol microtubul base backbon ensur integr function cell cycl depend duplic centrosom most unclear mechan control structur integr centriol show centrosom protein cep function scaffold coordin distal end properti centriol length stabil format distal subdist appendag cep fulfil divers function ensur centriolar local wdr recruit protein cep ofd distal end centriol promot assembl subdist appendag role remov daughter specif protein centrobin cep fop complex associ cep ofd control centriol microtubul length centrobin safeguard centriol distal end stabil especi compromis cep cell cep fop wdr axi secur centriol integr studi identifi cep guardian distal end region centriol without impact proxim pcm part
|
D018797;D002502;D008869;D009687
|
T026;T123;T116
|
36,315,003
|
geograph distribut space time cluster human ill major salmonella serotyp florida usa nontyphoid salmonellosi lead report foodborn ill florida although divers salmonella serotyp circul florida identifi geograph characterist major serotyp poor describ examin geospati pattern whole genom sequenc salmonella isol within seven major serotyp enteritidi newport javiana sandiego braenderup typhimurium metadata obtain florida depart health geograph distribut incid rate vari distinct serotyp ill enteritidi newport serotyp widespread florida incid rate javiana relat higher north compar south typhimurium concentr northwest monophas variant typhimurium limit south also evalu space time cluster isol zip code level use scan statist model space time cluster detect major serotyp multinomi scan statist found risk ill javiana higher north southwest fall compar major serotyp serotyp specif cluster analysi assist unpack associ distinct reservoir ill major serotyp florida
|
D012475;D012478
|
T007;T037
|
36,314,986
|
v atpasetorc mediat atf translat direct mitochondri upr activ c elegan adapt mitochondri function ever chang intra extracellular environ multipl mitochondri stress respons msr pathway includ mitochondri unfold protein respons uprmt evolv howev mitochondri stress signal sens relay uprmt transcript factor atf caenorhabd elegan remain larg unknown show panel vacuolar h atpas v atpas subunit target rapamycin complex torc activ essenti cytosol relay mitochondri stress atf induct uprmt mechanist mitochondri stress stimul v atpaserheb depend torc activ subsequ promot atf translat increas translat atf upon mitochondri stress furthermor reli set ribosom compon independ gcn pek signal final v atpas ribosom subunit requir mitochondri surveil mitochondri stress induc longev result reveal v atpas torc atf signal pathway link mitochondri stress uprmt intim crosstalk multipl organell
|
D029742;D000076222;D056811;D025262;D014157
|
T123;T126;T116;T043
|
36,314,932
|
demograph medic comorbid risk factor increas episod care cost follow lumbar fusion medicar patient object evalu medic comorbid surgic variabl independ risk factor increas health care cost medicar patient undergo lumbar fusion care episod limit lumbar fusion retrospect review center medicar medicaid innov cmmi bundl payment care improv bpci reimburs databas singl academ institut total episod care cost also collect multivari linear regress model develop identifi independ risk factor increas total episod care cost logist model surgic complic readmiss total medicar patient includ risk factor associ increas total episod care cost includ transforamin interbodi fusion tlif anterior lumbar interbodi fusion alif p alifplf ap fusion p level fuse p congest heart failur p hypertens end organ damag p liver diseas p inpati complic p day complic p day readmiss p common surgic complic postop anemia associ signific increas cost p femal sex p ap fusion p level fuse p cerebrovascular diseas p cardiac arrhythmia p fluid electrolyt disord p independ predictor surgic complic bodi mass index p ap fusion p independ predictor surgic readmiss among medic comorbid congest heart failur hypertens end organ damag liver diseas independ associ signific increas total episod care cost interbodi devic associ increas admiss cost
|
D013123;D006333;D006973
|
T061;T047;T046
|
36,314,931
|
promis prom realiz implement experi larg orthoped practic patient report outcom measur prom increas use research qualiti measur laud potenti improv patient center care aggreg report integr clinic practic howev publish studi result use prom clinic practic case studi describ implement use prom midwestern multispecialti medic group orthoped practic among patient undergo total knee hip surgeri specif rate prom use care team track time made avail electron health record time orthoped depart achiev patient prom survey respons rate baselin month post surgeri month post surgeri howev data access care team fewer associ clinic encount suggest make prom avail care team review electron health record even coupl relat high respons rate patient department leadership support enough encourag integr prom clinic care patient addit effort requir identifi barrier prom use clinic care test method enhanc use
|
D000071066;D009985
|
T170;T091
|
36,314,899
|
reorgan energi interfaci proton coupl electron transfer water oxid catalyst reorgan energi interfaci electron transfer et proton coupl et pcet conduct metal oxid sn ito surfac bound water oxid catalyst extract kinet data measur function thermodynam drive forc visibl light excit result rapid excit state inject k inj ito photo initi two interfaci reaction interest rate constant reaction increas drive forc g satur limit k max rate constant consist larger et pcet marcus gerisch analysi kinet data provid reorgan energi interfaci pcet ev et ev respect magnitud k max pcet found decreas ph behavior absent et decreas k max larger reorgan energi unwant compet pcet reaction ito oxid catalyst showcas signific kinet advantag drive solar water oxid high ph comput analysi reveal larger inner sphere reorgan energi contribut pcet et aris signific chang ru bond length pcet reaction extend marcus gerisch theori pcet includ excit electron proton vibron state proton donor acceptor motion provid appar reorgan energi ev studi demonstr marcus gerisch theori initi develop et reliabl extend pcet quantifi interpret reorgan energi observ experiment
|
D011522;D014867
|
T121;T196;T197
|
36,314,898
|
acrogenospora terricola sp nov fungal speci associ seed pioneer tree soil seed bank lowland forest panama current circumscrib acrogenospora acrogenosporacea minutisphaeral dothideomycet genus saprob hyphomycet distinct conidia although consid common cosmopolitan genus poor repres sequenc data neotrop repres present public sequenc databas consequ acrogenospora larg invis ecolog studi reli sequenc base identif part effort identifi fungi collect ecolog studi identifi strain acrogenospora isol cultur seed soil seed bank lowland tropic forest panama describ acrogenospora terricola sp nov base morpholog phylogenet analys confirm genus pantrop distribut observ acrogenospora infect seed terrestri environ contrast previous describ speci genus occur decay wood freshwat environ work highlight often hidden taxonom valu collect deriv ecolog studi fungal communiti way rich sequenc databas shed light ident distribut divers cryptic microfungi
|
D001203;D000068098
|
T004;T002
|
36,314,892
|
diagnost accuraci adjust low igg avid index predict acut toxoplasma gondii infect first trimest pregnanc congenit toxoplasmosi report diseas europ prevent antibodi serolog test introduc sever european countri part screen programm immunoglobulin g igg avid index test one test diagnos acut infect toxoplasma gondii nicoll et manceaux pregnant women howev low moder igg avid index give inconclus result predict woman status june end women includ nation screen program prevent congenit toxoplasmosi one hundr twenti six women consecut includ studi low moder igg avid everi woman possibl acut toxoplasmosi follow everi month till deliveri fifti eight women got infect month current pregnanc women infect earli pregnanc twenti nine pregnant women got infect secondthird trimest pregnanc new cut igg avid index cut abl exclud gondii acut infect first trimest good diagnost accuraci area curv auc confid interv ci sensit specif igg avid index measur woman serum first trimest pregnanc odd ratio acut infect gondii ci p measur igg avid index first trimest pregnanc exclud infect gondii good diagnost accuraci cohort women new cut could reduc number invas procedur amniocentesi put less pregnant women distress
|
D014125;D014123;D014122
|
T047;T204
|
36,314,886
|
identif novel antifreez peptid takifugu obscurus skin molecular mechan inhibit ice crystal growth foodborn hydrolyz antifreez peptid wide use food industri biomed field howev compon hydrolyz peptid complex molecular mechan remain unclear studi focus identif mechan analysi novel antifreez peptid takifugu obscurus skin tradit method comput assist techniqu result show three peptid egpraggapg gdagpsgpagptg geagpagpag possess cryoprotect via reduc freez point inhibit ice crystal growth molecular dock confirm cryoprotect properti relat peptid structur especi helix hydrogen bond site moreov antifreez peptid doubl face control ice crystal affect arrang surround water molecul thus exhibit strong antifreez activ investig deepen comprehens mechan antifreez peptid molecular scale novel effici antifreez peptid develop antifreez materi design appli food industri
|
D007053;D023741
|
T197;T013
|
36,314,885
|
suicid risk mental health general popul french polynesia report burden suicid ideat suicid attempt general popul french polynesia fp aim improv suicid prevent mental health care assess preval suicid risk major mental health disord care among adult fp
|
D008603;D001523
|
T041;T048
|
36,314,884
|
psychometr properti korean version child sexual behavior inventori studi examin psychometr properti korean version child sexual behavior inventori csbi children year age particip compris communiti sampl cs children age three nine year sexual abus sa children age rang parent rate csbi child behavior checklist cbcl traumat symptom checklist young children tscyc examin intern consist measur reliabl conduct anova discrimin pearson correl converg diverg valid reliabl coeffici indic intern consist signific correl sexual behavior intern extern behavior problem sampl r p correl post traumat stress disord symptom sexual concern sa sampl high r p signific differ sexual behavior cs sa find demonstr reliabl valid korean version csbi use identifi children suspect sexual abus howev research identifi cultur differ sexual behavior cs
|
D002650
|
T048
|
36,314,880
|
impact bariatr surgeri procedur modul cardiometabol risk factor patient sever obes month follow evalu effect one anastomosi gastric bypass oagb roux en gastric bypass rygb sleev gastrectomi sg cardiometabol risk factor cmrfs patient sever obes
|
D009767;D003924;D015390;D050110
|
T061;T047
|
36,314,879
|
overal surfaci antenna immobil boost carrier migrat visibl light superoxid generat artifici photosynthesi effici restrict cover introduc light absorb antenna could general immobil specif surfac site semiconductor highlight emerg interact strategi realiz overal surfaci antenna immobil onto semiconductor support larg scale built electr field establish strong drive photocarri migrat catalyt center accompani enhanc light absorpt take porphyrin zif prototyp theoret calcul experiment result show photocatalyt system overal surfaci antenna could absorb broader visibl light form abund photocarri transport pathway porphyrin zif boost generat superoxid organ synthesi effici work develop univers strategi design effici artifici photosynthet system
|
D013481;D011166
|
T121;T123;T109
|
36,314,863
|
direct oral anticoagul revers pediatr emerg depart direct oral anticoagul use adult popul year use frequent pediatr direct oral anticoagul chosen preferenti requir close outpati monitor equal better safeti profil easi patient take warfarin previous common use oral anticoagul act vitamin k antagonist direct oral anticoagul mechan action differ direct inhibit part coagul cascad accomplish end goal given differ mechan requir altern medic proper revers concern overdos life threaten bleed review outlin common use direct oral anticoagul pediatr popul support main adult data avail proper revers medic time need
|
D000088542;D000925
|
T061;T121
|
36,314,862
|
evalu novel point care ultrasound curriculum first year pediatr resid aim studi evalu novel point care ultrasound pocus educ curriculum pediatr resid
|
D007396
|
T065;T097
|
36,314,861
|
evalu clinic impact novel pediatr emerg medicin curriculum asthma outcom beliz respiratori relat complaint prompt pediatr visit karl heusner memori hospit author khmha emerg depart ed beliz develop taught novel pediatr respiratori emerg modul generalist practition assess curriculum clinic impact pediatr asthma emerg manag
|
D000070316;D001249
|
T047;T091
|
36,314,851
|
preval diabet retinopathi eastern mediterranean region systemat review meta analysi individu studi eastern mediterranean region emr shown high preval diabet retinopathi conduct meta analysi yield estim preval diabet type retinopathi emr addit explor potenti modul
|
D003930;D003924
|
T047
|
36,314,844
|
microfluid platform studi bioclog porous media bacteri biofilm found sever environment industri porous media includ soil filtrat membran biofilm grow certain flow condit clog pore therebi redirect local fluid flow abil biofilm clog pore call bioclog tremend effect local permeabl porous medium creat pressur buildup system impact mass flow understand interplay biofilm growth fluid flow differ physic condit eg differ flow veloc pore size present studi microfluid platform develop visual biofilm develop use microscop extern impos control physic condit biofilm induc pressur buildup porous medium measur simultan use pressur sensor later correl surfac coverag biofilm present platform provid baselin systemat approach investig bioclog caus biofilm porous media flow condit adapt studi environment isol multispeci biofilm
|
D044085;D018441
|
T090;T007
|
36,314,843
|
high resolut ultrasonographi analysi orthotop atc tumor genet engin mous model anaplast thyroid carcinoma atc associ poor prognosi short median surviv time effect treatment improv outcom signific genet engin murin model mimic atc progress may help research studi treatment diseas cross three differ genotyp mice tpo creert braf cawt trp ex ex transgen atc model develop atc murin model induc intraperiton inject tamoxifen overexpress braf delet trp tumor generat within month high resolut ultrasound appli investig tumor initi progress dynam growth curv obtain measur tumor size compar magnet reson imag mri comput tomographi scan ultrasound advantag observ atc murin model noninvas portabl real time without radiat exposur high resolut ultrasound suitabl dynam multipl measur howev ultrasonograph examin thyroid mice requir relev anatom knowledg experi articl provid detail procedur util high resolut ultrasound scan tumor transgen atc model meanwhil ultrason paramet adjust ultrasound scan skill anesthesia recoveri anim element need attent process list
|
D065646;D013964
|
T191
|
36,314,840
|
function assess donor heart ex situ perfus insight pressur volum loop surfac echocardiographi heart transplant remain gold standard treatment advanc heart failur howev current critic organ shortag result alloc grow number donor heart extend criteria margin graft associ high risk primari graft failur may benefit ex situ perfus transplant technolog allow extend organ preserv use warm oxygen blood perfus continu metabol monitor nesp devic current avail clinic practic perfus organ unload non work state allow function assess beat heart therefor develop origin platform nesp work mode condit adjust left ventricular preload afterload protocol appli porcin heart ex situ function assess heart achiev intracardiac conduct catheter surfac echocardiographi along descript experiment protocol herein report main result well pearl pitfal associ acquisit pressur volum loop myocardi power nesp correl hemodynam find ultrasound variabl major interest especi rehabilit donor heart transplant protocol aim improv assess donor heart increas donor pool reduc incid primari graft failur
|
D014019;D016027
|
T061;T098
|
36,314,836
|
lethal bioassay use artemia salina l natur product use sinc ancient time produc medicin nowaday plenti chemotherapeut drug obtain natur sourc use plethora diseas unfortun compound often display system toxic advers effect order better evalu toler select potenti bioactiv sampl brine shrimp artemia salina general use model lethal studi salina test base abil studi bioactiv compound kill microcrustacean larval stage nauplii method repres conveni start point cytotox studi well general toxic screen synthet semisynthet natur product consid simpl quick low cost assay compar mani assay vitro cell yeast strain zebrafish rodent general suitabl aforement purpos moreov easili perform even without specif train overal salina assay repres use tool preliminari toxic evalu select compound bio guid fraction natur product extract
|
D001156;D001688
|
T123;T121;T204
|
36,314,835
|
neuronavig laparoscopi guid ventriculoperiton shunt insert treatment hydrocephalus hydrocephalus common adult neurosurg condit typic requir treatment cerebrospin fluid csf shunt ventriculoperiton vp shunt common type unfortun failur rate vp shunt alarm high patient requir revis surgeri within year vp shunt failur may occur due infect cathet misposit migrat occlus undertook joint neurosurgeri general surgeri collabor year prospect non random consecut qualiti improv cohort studi reduc rate ventriculoperiton vp shunt failur adult patient tertiari care institut initi combin use electromagnet stereotact neuronavig guid placement proxim cathet laparoscopi place distal cathet direct visual laparoscop assist distal cathet anchor small hole creat falciform ligament place right retrohepat space free omentum adhes bowel might obstruct cathet tip surgeri perform use shunt infect prevent protocol reduc risk shunt infect present intraop video surgic procedur complianc shunt infect reduct strategi combin util neuronavig laparoscopi techniqu adult vp shunt surgeri result reduct risk overal shunt failur signific posit impact regard shunt failur free patient outcom among patient underw vp shunt surgeri use strategi underscor valu associ use modern intraop techniqu cross specialti collabor vp shunt surgeri
|
D006849;D010535
|
T061;T060;T033;T019;T047
|
36,314,833
|
investig interact histon modifi enzym transcript factor vivo fluoresc reson energi transfer epigenet regul gene express common affect histon modifi enzym hmes generat heterochromat euchromat histon mark transcript repress activ respect hmes recruit target chromatin transcript factor tfs thus detect character direct interact hmes tfs critic understand function specif better studi would biolog relev perform vivo within live tissu protocol describ visual interact plant leav plant histon deubiquitinas plant transcript factor use fluoresc reson energi transfer fret allow detect complex protein molecul within nm two variat fret techniqu present se fret sensit emiss ab fret acceptor bleach energi transfer non radiat donor acceptor emit radiat donor upon photobleach acceptor se fret ab fret approach adapt easili discov interact protein planta
|
D031541;D006657
|
T123;T059;T116
|
36,314,830
|
three dimension cultur murin colon crypt studi intestin stem cell function ex vivo intestin epithelium regener everi day control intestin epitheli stem cell iesc popul locat bottom crypt region iesc includ activ stem cell self renew differenti various epitheli cell type quiescent stem cell serv reserv stem cell case injuri regener intestin epithelium control self renew differenti capabl activ iesc addit balanc crypt stem cell popul mainten stem cell nich essenti intestin regener organoid cultur import attract approach studi protein signal molecul environment cue regul stem cell surviv function model less expens less time consum manipulat anim model organoid also mimic tissu microenviron provid vivo relev present protocol describ isol colon crypt embed isol crypt cell three dimension gel matrix system cultur crypt cell form colon organoid capabl self organ prolifer self renew differenti model allow one manipul environ knock specif protein claudin activatingdeactiv signal pathway etc studi effect influenc function colon stem cell specif role tight junction protein claudin colon stem cell function examin claudin vital maintain intestin homeostasi barrier function integr knockout claudin mice induc inflammatori bowel diseas like phenotyp exhibit intestin inflamm epitheli hyperplasia weight loss mucos ulcer epitheli cell slough adenoma previous report claudin requir intestin epitheli stem cell function small intestin protocol colon organoid cultur system establish studi role claudin larg intestin
|
D013234;D003106
|
T081;T023;T025
|
36,314,816
|
electropor method transform rickettsia spp fluoresc protein express shuttl vector tick cell line rickettsios caus broad rang oblig intracellular bacteria belong genus rickettsia transmit vertebr host bite infect arthropod vector date emerg emerg epidem rickettsios remain public health risk due difficulti diagnosi diagnost method limit standard univers access misdiagnosi result lack recognit sign symptom may result delay antibiot treatment poor health outcom comprehens understand rickettsia characterist would ultim improv clinic diagnosi assess treatment improv control prevent diseas function studi rickettsi gene crucial understand role pathogenesi paper describ procedur electropor rickettsia parkeri strain tate hell shuttl vector pramdsfa select transform r parkeri tick cell cultur antibiot spectinomycin streptomycin method also describ local transform r parkeri tick cell use confoc immunofluoresc microscopi use techniqu check transform vector cell line similar approach also suitabl transform rickettsia
|
D013987;D026863;D012281;D012282
|
T047;T007;T204
|
36,314,815
|
use time laps microscopi stage specif nuclear deplet protein studi meiosi cerevisia time laps fluoresc microscopi revolution understand meiotic cell cycl event provid tempor spatial data often seen imag fix cell bud yeast prove import model organ studi meiotic chromosom segreg mani meiotic gene high conserv time laps microscopi meiosi bud yeast allow monitor differ meiotic mutant show mutat disrupt meiotic process howev mani protein function multipl point meiosi use loss function meiotic null mutant therefor disrupt earli process block disturb later process make difficult determin phenotyp associ individu role circumv challeng protocol describ protein condit deplet nucleus specif stage meiosi monitor meiotic event use time laps microscopi specif protocol describ cell synchron prophas anchor away techniqu use deplet protein nucleus specif meiotic stage time laps imag use monitor meiotic chromosom segreg exampl use techniqu kinetochor protein ctf deplet nucleus differ time point meiosi number chromatin mass analyz end meiosi ii overal protocol adapt deplet differ nuclear protein nucleus monitor meiotic divis
|
D012441;D029701
|
T004;T116
|
36,314,814
|
deciph high resolut chromatin organ via captur hi c spatial organ genom contribut function regul mani context includ transcript replic recombin repair understand exact causal genom topolog function therefor crucial increas subject intens research chromosom conform captur technolog c allow infer structur chromatin measur frequenc interact region genom describ fast simpl protocol perform captur hi c c base target enrich method character allel specif organ megabas size genom target high resolut captur hi c target region captur array biotinyl probe downstream high throughput sequenc thus higher resolut allel specif achiev improv time effect afford technolog demonstr strength captur hi c protocol appli mous x inactiv center xic master regulatori locus x chromosom inactiv xci
|
D002843;D002875
|
T026;T116
|
36,314,813
|
high throughput platform cultur imag organoid character larg number three dimension organotyp cultur organoid differ resolut scale current limit standard imag approach protocol describ way prepar microfabr organoid cultur chip enabl multiscal live imag user friend instrument requir minim manipul capabl organoidsh imag throughput cultur chip compat air immers object air water oil silicon wide rang common microscop eg spin disk point scanner confoc wide field brightfield moreov use light sheet modal singl object singl plane illumin microscopi spim technolog sospim protocol describ give detail step prepar microfabr cultur chip cultur stain organoid short length time requir becom familiar consum equip easili found normal biolab imag capabl demonstr commerci standard microscop eg spin disk reconstruct wide field microscopi routin monitor
|
D009940;D021621
|
T062;T060;T073;T024
|
36,314,812
|
reconstruct human retinoblastoma vitro human rb pediatr cancer lethal treatment administ rb origin cone precursor relat rare rodent model meanwhil regard interspeci differ human rodent diseas model deriv human benefici uncov mechan human rb seek target therapi herein protocol describ generat two gene edit hesc line biallel rb point mutat rb mutmut rb knockout mutat rb respect process retin develop format rb observ rb cell line also establish segreg rb organoid altogeth differenti gene edit hesc line retin organoid use combin differenti protocol success reconstruct human rb dish identifi cone precursor origin would provid help diseas model observ retinoblastoma genesi prolifer growth well develop novel therapeut agent
|
D012175;D019572
|
T191
|
36,314,811
|
lumican extract amniot membran determin storag temperatur lumican small leucin rich proteoglycan human amniot membran promot corneal epitheli organ collagen fiber maintain corneal transpar present work method protein extract obtain lumican propos addit stabil lumican extract ame store differ temperatur time period evalu mg thaw mechan de epitheli de epitheli frozen crush fine powder obtain solubil ml salin buffer proteas inhibitor centrifug protein extract supernat collect store c c room temperatur rt day afterward lumican quantifi ame techniqu allow access acquir protocol lumican extract lumican concentr affect storag time temperatur condit lumican ame day store c c signific higher ame lumican extract could use develop treatment pharmaceut solut studi need determin use ame lumican epitheli wound heal process
|
D000650;D014945
|
T018;T040
|
36,314,805
|
isol analysi traceabl function extracellular vesicl plasma solid tissu circul tissu resid extracellular vesicl ev repres promis target novel theranost biomark emerg import player mainten organism homeostasi progress wide spectrum diseas current research focus character endogen exosom endosom origin microvesicl bleb plasma membran gain increas attent health sick featur abund surfac molecul recapitul membran signatur parent cell reproduc procedur present base differenti centrifug extract character ev plasma solid tissu bone protocol describ subsequ profil surfac antigen protein cargo ev thus traceabl deriv identifi compon relat potenti function method use correl function mechanist analysi ev biolog physiolog patholog studi
|
D000067128;D055354;D055252
|
T026
|
36,314,804
|
explor caspas mutat post translat modif molecular model approach apoptosi type program cell death elimin damag cell control develop tissu homeostasi multicellular organ caspas famili cystein proteas play key role apoptosi initi execut matur caspas activ fine tune post translat modif high dynam fashion assess effect post translat chang potenti site routin mutat residu persist modif exampl serin residu replac alanin aspart acid howev substitut could alter caspas activ site conform lead disturb catalyt activ cellular function moreov mutat amino acid residu locat critic posit could also break structur function caspas lead apoptosi perturb avoid difficulti employ mutat residu molecular model approach readili appli estim potenti effect amino acid substitut caspas structur present protocol allow model wild type caspas mutant form biomolecular simul packag amber supercomput facil test effect mutat protein structur function
|
D020169;D017209
|
T123;T126;T116;T043
|
36,314,803
|
label retent expans microscopi lr exm enabl super resolut imag high effici label expans microscopi exm sampl prepar techniqu combin light microscopi method increas resolut embed cell tissu swellabl hydrogel sampl physic expand three sixteen fold linear dimens compar origin size therefor effect resolut microscop increas expans factor major limit previous introduc exm reduc fluoresc polymer digest procedur overcom limit label retent expans microscopi lr exm develop prevent signal loss great enhanc label effici use set novel trifunct anchor techniqu allow one achiev higher resolut investig cellular subcellular structur nanometr scale minim fluoresc signal loss lr exm use immunofluoresc label also self label protein tag snap clip tag thus achiev higher label effici work present procedur troubleshoot immunostain base approach well discuss self label tag approach lr exm altern
|
D020100
|
T122
|
36,314,795
|
microfluid acoustophoresi flowthrough separ gram negat bacteria use aptam affin bead articl describ fabric oper microfluid acoustophoret chip use microfluid acoustophoresi techniqu aptam modifi microbead use fast effici isol gram negat bacteria medium method enhanc separ effici use mix long squar microchannel system sampl buffer inject inlet port flow control bead center sampl separ ac power appli piezoelectr transduc via function generat power amplifi generat acoust radiat forc microchannel bifurc channel inlet outlet enabl simultan separ purif concentr devic recoveri rate puriti x dose concentr studi demonstr recoveri rate puriti higher exist method separ bacteria suggest devic separ bacteria effici
|
D044085;D046210
|
T090;T059
|
36,314,794
|
use vivo imag screen morphogenesi phenotyp candida albican mutant strain activ infect mammalian host candida albican import human pathogen abil switch morpholog form central pathogenesi morpholog chang regul complex signal network control respons environment stimuli regulatori compon high studi almost studi use varieti vitro stimuli trigger filament determin morphogenesi regul pathogenesi process develop vivo microscopi system obtain high spatial resolut imag organ undergo hyphal format within mammalian host protocol present describ use system screen small collect c albican mutant strain allow us identifi key regul morphogenesi occur site infect repres result present demonstr regul morphogenesi transcript regul efg consist phenotyp vitro vivo wherea regul adenyl cyclas cyr signific differ phenotyp vivo compar vitro
|
D002176;D005656
|
T123;T004;T116
|
36,314,792
|
metastat melanoma present dyspepsia case report gastrointestin tract uncommon site metastasi gastrointestin metastasi melanoma usual asymptomat often affect small intestin colon rare affect stomach patient year old man present gradual worsen dyspepsia week durat mention gastrointestin symptom anem histori auricular melanoma resect black lesion diamet approxim mm detect bodi stomach upper gastrointestin endoscopi biopsi taken diagnosi metastat melanoma confirm immunohistochemistri ihc gastrointestin work comput tomographi ct positron emiss tomographi pet reveal addit lesion lesion stomach resect new cours chemotherapi initi lower threshold consid gastrointestin work patient melanoma
|
D004415;D008545;D005770;D016609
|
T184;T191
|
36,314,789
|
transtubular endoscop posterolater decompress l lumbar later disc herniat report novel techniqu c arm free transtubular l nerv decompress ct base navig reduc radiat hazard procedur perform general anesthesia neuromonitor patient place prone posit oper carbon tabl navig refer frame place percutan contralater sacroiliac joint spinous process ct scan imag obtain instrument registr l foramin level confirm navig probe entri point mark use approxim cm skin incis subcutan tissu muscl dissect navig first dilat aim l kambin triangl sequenti dilat perform mm tube use fix frame bone around kambin triangl remov navig burr later disc herniat l nerv root identifi retract disc fragment remov navig guid tubular endoscop decompress effect procedur radiat hazard surgeon oper room staff
|
D007405
|
T047
|
36,314,785
|
investig electrophysiolog thermograph safeti paramet surgic energi devic thyroid parathyroid surgeri porcin model thyroid parathyroid surgeri surgic energi devic sed provid effici hemostasi convent clamp tie hemostasi area rich blood suppli howev sed activ near recurr laryng nerv rln heat generat sed may injur nerv irrevers safe appli sed thyroidparathyroid surgeri articl introduc experiment porcin model studi investig activ cool safeti paramet sed standard electrophysiolog ep thermograph tg procedur respect ep safeti paramet experi continu intraop neuromonitor c ionm appli demonstr rln function real time ep activ studi evalu safe activ distanc sed ep cool studi evalu safe cool time sed tg safeti paramet experi thermal imag camera use record temperatur chang activ sed tg activ studi evalu later thermal spread distanc sed activ dri humid environ whether smoke splash generat tg cool studi evalu cool time help establish safeti paramet newli develop sed use thyroidparathyroid surgeri provid safeti guidelin avoid rln injuri relat complic
|
D013961;D061226
|
T023;T037
|
36,314,774
|
precis stabl edg orient signal human first order tactil neuron fast adapt type fa slow adapt type sa first order neuron human tactil system distal axon branch skin form mani transduct site yield recept field mani high sensit zone subfield previous demonstr arrang allow fa sa neuron signal geometr featur touch object specif orient rais edg scan fingertip show signal oper fine edg orient differ stabl across broad rang scan speed mms condit relev real world hand use found fa sa neuron weak signal fine edg orient differ via intens spike respons consid singl scan speed neuron type show much stronger edg orient signal sequenti structur evok spike train fa neuron perform better sa neuron repres spatial domain sequenti structur strike invari across scan speed especi natur use tactil spatial discrimin task speed invari suggest neuron respons structur via sequenti stimul subfield thus link capac termin organ skin inde spatial precis elicit action potenti ration match spatial acuiti subfield arrang correspond spatial period similar dimens individu fingertip ridg
|
D014110;D055698
|
T041;T042
|
36,314,761
|
tunabl popul dynam synthet filament cocultur microbi cocultur use tool stimul natur product biosynthesi howev studi often empir combin differ organ without deeper understand popul dynam filament organ offer vast metabol divers develop model filament cocultur cellulolyt fungus trichoderma reesei rut c noncellulolyt bacterium streptomyc coelicolor cocultur set use cellulos carbon sourc establish depend coelicolor hydrolys sugar releas reesei cellulas provid detail insight cocultur dynam appli high throughput onlin monitor respir rate fluoresc tag strain respir rate allow us distinguish condit success cellulas format furthermor dissect individu strain contribut reesei coelicolor tag mcherri mneongreen mng fluoresc protein respect evalu vari inocul ratio observ partner outcompet given high inocul advantag nonetheless adequ proport simultan growth partner cellulas pigment product could determin final popul dynam also tune modul abiot factor increas osmol provid growth advantag coelicolor contrast increas shake frequenc negat effect coelicolor biomass format promot reesei comprehens analysi fill import knowledg gap control complex cocultur acceler setup tailor made cocultur bioprocess
|
D002480;D014242
|
T121;T004;T126;T116
|
36,314,760
|
bacteriophag pass candl shape porous ceram filter applic collect virus soil water despit ubiqu virus soil divers soil water explor main due difficulti collect hydrolog soil water usual collect use porous candl studi propos use porous candl new tool sampl virus soil water analyz passag ceram part candl recoveri virus determin filtrat laboratori condit use three model bacteriophag ms x escherichia coli neutral acid ph field experi carri soil water filtrat viral identif metagenom shotgun perform neutral ph bacteriophag test success pass porous candl filtrat process reduct log log log ms x respect ph passag ms affect x underw slight reduct recoveri probabl caus adsorpt onto filter materi regard applic porous candl field result obtain allow success recoveri virus expos porous candl new method suitabl collect virus soil water context studi viral communiti
|
D001435;D014780
|
T005
|
36,314,759
|
pbbr base vector incp group plasmid compat methylorubrum extorquen plasmid one import genet tool basic research biotechnolog enabl rapid genet manipul present novel pbbr base plasmid methylorubrum extorquen model methylotroph use develop c base microbi cell factori develop vector compat far main use pcm plasmid system transfer pbbr base plasmid pmis show extrem low transform rate caus strong growth defect isol suppressor mutant improv growth led isol variant pmisb higher transform rate less pronounc growth defect phenotyp could shown result mutat promotor region rep gene moreov cotransform pmisb pcm possibl result transform show stronger growth defect comparison singl pmisb transform surpris cotransform carri pcm pmisb deriv contain mcherri report construct show higher fluoresc level strain contain pmisb base report plasmid correspond pcm deriv relat plasmid copi number determin experi confirm hypothesi increas copi number pmisb strain carri plasmid despit slight metabol burden caus pmisb plasmid strong expand genet toolbox extorquen
|
D010957
|
T123;T114
|
36,314,758
|
geobact sulfurreducen metabol differ donoracceptor ratio geobact speci great applic potenti remedi process electrobiotechnolog applic understand metabol enabl target orient optim process typic electron donor carbon sourc geobact speci acet fumar usual electron acceptor could show depend donoracceptor ratio batch cultiv geobact sulfurreducen differ product pattern occur donoracceptor ratio malat accumul intermedi product metabol succin subsequ end cultiv ratio fumar consum succin produc approxim fumar ad excess malat accumul ferment broth without metabol addit acet stationari cell malat concentr decreas immedi addit succin synthes final shown also rest cell g sulfurreducen could effici convert fumar malat without addit electron donor overal demonstr alter donoracceptor ratio target optim metabolit convers g sulfurreducen realiz
|
D045302
|
T007
|
36,314,757
|
dna extract bias pronounc microbi eukaryot prokaryot dna extract preserv bias recur topic dna sequenc base microbi ecolog differ methodolog lead distinct outcom demonstr especi studi investig prokaryot communiti composit eukaryot microb ubiquit divers increas subject investig addit bacteria archaea howev littl known choic dna preserv extract methodolog impact perceiv eukaryot communiti composit studi compar effect two dna preserv method six dna extract method communiti profil eukaryot prokaryot phototroph biofilm seagrass zostera marina leav baltic sea found wherea dna preserv extract method caus signific bias perceiv communiti composit eukaryot prokaryot extract bias pronounc eukaryot prokaryot particular soft bodi hard shell eukaryot like nematod diatom respect differenti abund depend extract method conclud care consider dna preserv extract methodolog crucial achiev repres communiti profil eukaryot marin biofilm like habitat contain divers eukaryot microbi communiti
|
D056890;D064307
|
T001;T032;T028;T204
|
36,314,756
|
de novo biosynthesi aminoadip via multi strategi metabol engin escherichia coli non protein amino acid aminoadip use field medicin chemic engin food scienc other exampl aminoadip import precursor product lactam antibiot current synthesi aminoadip depend chemic catalysi disadvantag high cost low yield serious pollut studi construct biosynthesi pathway aminoadip escherichia coli use lysin precursor addit regul cell metabol improv titer aminoadip via multi strategi metabol engin first novel synthet pathway construct realiz de novo synthesi aminoadip titer mgl second key enzym involv enhanc precursor synthesi overexpress co fixat process introduc led increas aminoadip concentr reach mgl respect third cofactor regul use maintain coupl balanc materi energi intracellular aminoadip concentr reach mgl fourth weaken synthesi acet acid use strengthen synthesi aminoadip result enhanc aminoadip concentr time reach mgl final combin optim use promot product aminoadip titer aminoadip reach mgl strain ecn mgl strain ecn time higher parent strain effort gl aminoadip produc fed batch condit strain ecn studi first present effect biosynthesi aminoadip e coli use multi strategi metabol engin
|
D060847;D029968
|
T063;T116
|
36,314,755
|
isol extend spectrum lactamas produc escherichia coli japanes red fox vulp vulp japonica antimicrobi resist global concern requir one health approach given wild anim harbor antimicrobi resist bacteria arb investig presenc fecal sampl wild anim use deoxychol hydrogen sulfid lactos agar without cefotaxim ctx mgl thus isol ctx resist escherichia coli two japanes red fox fecal sampl one strain h st fimh ctx produc e coli carri gene aph ib aph ia aph id mdf sitabcd sul tet tet b wherea h st fimh ctx produc e coli carri mdf sitabcd show fluoroquinolon resist thus presenc extend spectrum lactamas produc wild fox suggest spillov arb human activ wild anim
|
D004926;D004927
|
T047;T007
|
36,314,754
|
whole genom sequenc genom scale metabol model chromohalobact canadensi b explor salt toler biotechnolog use salt toler organ increas use industri product high valu biomolecul due better adapt compar mesophil chromohalobact canadensi one earli halophil show promis biotechnolog potenti explor date advanc high throughput technolog whole genom sequenc allow depth insight potenti organ frontier system biolog time genom scale metabol model gem enabl phenotyp predict mechanist represent metabol sequenc analyz genom c canadensi b use reconstruct gem analyz gem use flux balanc analysi valid literatur data c canadensi show c canadensi b metabol versatil organ mani featur stress osmot adapt pathway produc ectoin polyhydroxybutyr also predict gem reveal abil grow sever carbon sourc minim medium reproduc osmoadapt phenotyp overal studi reveal insight genom c canadensi b provid genom data draft gem serv first step toward better understand metabol novel applic industri biotechnolog
|
D055049;D055353
|
T040;T007
|
36,314,753
|
enrich captiv condit natur element prevent loss wild like gut microbiota shape composit variat two small mammal continu growth gut microbiota studi captiv model anim elucid import role host biolog pursuit retain wild like microbi communiti becom increas import obtain repres result captiv anim studi assess gut microbiota two wild caught small mammal name crocidura russula eulipotyphla insectivor apodemus sylvaticus rodentia omnivor chang bring captiv analyz fecal sampl sylvaticus c russula immedi bring captiv week later spread two hous treatment natur setup enrich element fresh collect natur laboratori setup steril artifici element sequenc v v region recombin rna gene found initi microbi divers drop captiv speci regardless treatment communiti composit underw chang similar magnitud speci treatment howev observ tempor develop gut microbiom took differ trajectori ie chang differ direct differ treatment particular c russula suggest c russula may suscept environment chang result experi support use microbi enrich environ retain wild like microbi divers composit yet show specif hous condit signific affect drift microbi communiti captiv
|
D000069196;D064307
|
T032;T007;T028;T001
|
36,314,752
|
brucella ceti brucella pinnipediali genom character unveil genet featur highlight zoonot potenti gram negat bacteria brucella ceti brucella pinnipediali circul marin environ primarili infect marin mammal caus often fatal diseas name brucellosi increas brucellosi among sever speci cetacean pinnip togeth report sporad human infect rais concern zoonot potenti pathogen larg scale may pose threat coastal communiti worldwid therefor character b ceti b pinnipediali genet featur prioriti better understand patholog factor may impact global health moreov depth function analysi b ceti b pinnipediali genom context virul pathogenesi undertaken far within pictur present compar whole genom character b ceti b pinnipediali genom avail public resourc uncov collect genet tool possess aquat bacteri speci compar zoonot terrestri relat show b ceti b pinnipediali genom display wide host rang infect capabl polyphylet phylogeni within genus show genom structur fit canon definit close function genom annot led identifi gene relat sever pathway involv mechan infect other confer pan suscept antimicrobi set virul gene highlight similar b ceti b pinnipediali genotyp brucella spp display human infect phenotyp
|
D002002;D002006;D010872
|
T047;T007;T015
|
36,314,751
|
isol test novel yeast strain lignin usag capabl phenol compound resist five yeast fungi strain ie two cryptococcus albidus one candida guillermondii two candida tropicali isol sugarcan test use lignin sole carbon sourc potenti grow presenc phenol phenol deriv ie pentachlorophenol p nitrophenol full set isol yeast show ligninolyt activ achiev least lignin degrad day c albidus js b strain highest ligninolyt activ achiev lignin degrad within day increas activ associ product ligninolyt laccas enzym test yeast fungi strain show growth presenc high concentr phenol compound ie mgl phenol mgl p nitrophenol mgl pentachlorophenol show signific potenti lignin lignin product degrad five strain potenti use biolog treatment process contamin effluent paper pulp bleach phenol phenol deriv biodegrad process industri wastewat effluent
|
D008031;D010416
|
T123;T131;T109
|
36,314,750
|
compar analysi listeria monocytogen plasmid transcriptom reveal common plasmid specif gene express pattern high express noncod rnas recent research demonstr listeria monocytogen plasmid contribut stress surviv howev studi analyz gene express pattern l monocytogen plasmid studi identifi four previous publish stress respons associ transcriptom data set studi plasmid harbor l monocytogen strain includ analysi plasmid transcriptom four transcriptom data set encompass three distinct plasmid three differ l monocytogen strain differenti gene express analysi plasmid reveal number differenti express de l monocytogen plasmid gene rang log fold chang depend plasmid gene often found de includ cadmium resist gene cada cadc gene encod putat nadh peroxidas putat ultraviolet resist gene uvrx sever uncharacter noncod rnas ncrnas plasmid encod ncrnas consist among highest express gene addit one data set util experiment condit two differ strain harbor distinct plasmid found gene express pattern two l monocytogen plasmid high diverg despit ident treatment data suggest plasmid specif gene express respons environment stimuli differenti plasmid regul mechan l monocytogen strain find understand dynam express l monocytogen plasmid encod gene divers environment condit highlight need expand studi l monocytogen plasmid gene function
|
D008089
|
T007
|
36,314,749
|
defect dna doubl strand break repair resensit antibiot resist escherichia coli multipl bactericid antibiot antibiot resist becom increas preval amongst bacteri pathogen urgent need develop new type antibiot novel mode action one promis strategi develop resist breaker compound inhibit resist mechan thus resensit bacteria exist antibiot current studi identifi bacteri dna doubl strand break repair promis target develop resist break co therapi examin genet variant escherichia coli combin antibiot resist determin dna repair defect observ defect doubl strand break repair pathway led signific resensit toward five bactericid antibiot repres differ function class effect rang partial full resensit ciprofloxacin nitrofurantoin sensit manifest reduct minimum inhibitori concentr kanamycin trimethoprim sensit manifest increas rate kill high antibiot concentr ampicillin repair defect dramat reduc antibiot toler ciprofloxacin nitrofurantoin trimethoprim induc promutagen sos respons disrupt doubl strand break repair strong dampen induct sos antibiot find suggest break repair inhibitor develop could resensit antibiot resist bacteria multipl class exist antibiot may suppress develop de novo antibiot resist mutat
|
D029968;D004927
|
T047;T116
|
36,314,748
|
local coti exsi protein exosporium basal layer bacillus anthraci spore infecti form zoonot bacteri pathogen bacillus anthraci outermost spore layer exosporium compris basal layer extern glycoprotein nap layer major structur protein inner basal layer coti mother cell central pole bottlecap exsi around rest spore basi cap noncap specif coti exsi protein current unknown investig role sequenc differ protein local exosporium assembl found sequenc differ less import time express respect gene posit inner basal layer structur protein fusion construct fluoresc protein fuse n terminus result poor incorpor wherea fusion carboxi terminus coti exsi result good incorpor howev complement studi reveal fusion construct although accur indic protein local fulli function model present explain local pattern observ bacteri two hybrid studi escherichia coli host use examin protein protein interact full length truncat protein n terminus amino acid sequenc exsi coti appear recogn spore protein locat spore interspac consist interact seen exsi coti interspac protein cote coto known involv exosporium attach
|
D001408
|
T007
|
36,314,747
|
bacteri composit swedish raw drink water reveal three major interact ubiquit metacommun surfac raw water use sourc drink water product critic resourc sensit contamin conduct studi swedish raw water sourc aim identifi mutual co occur metacommun bacteria environment factor drive pattern
|
D060766
|
T167
|
36,314,746
|
comparison dna purif method high throughput sequenc fungal communiti wine ferment high throughput sequenc approach target taxonom discrimin locus allow depth insight microbi communiti composit although microorgan histor investig cultiv artifici cultur media method present strong limit sinc limit proport microorgan grown vitro pitfal appear even limit enolog winemak process wide rang mold yeast bacteria observ differ stage ferment cours understand dynam communiti impact wine qualiti therefor stand major challeng futur enolog although high throughput sequenc alreadi allow investig fungal communiti avail compar studi focus perform microbi deoxyribonucl acid dna extract enolog matrix studi aim provid comparison five select extract method assay must ferment must well finish wine procedur evalu accord extract yield puriti extract dna robust downstream molecular analys includ polymeras chain reaction high throughput sequenc fungal communiti altogeth two five assess microbi dna extract method dneasi powersoil pro kit ezna food dna kit appear suitabl robust evalu microbi communiti wine sampl consequ studi provid robust tool facilit upcom studi investig microbi communiti winemak use high throughput sequenc
|
D014920;D000072761
|
T168;T004
|
36,314,740
|
effect discontinu antihypertens drug frailti syndrom outpati year prospect design retrospect chart review pilot studi investig effect discontinu antihypertens drug characterist patient frailti syndrom
|
D000073496
|
T033;T184;T046
|
36,314,739
|
gold enough platinum standard quantum chemistri n cost paper extend rank reduc coupl cluster formal calcul non iter energi correct due quadrupl excit two major compon propos formal first approxim compress quadrupl excit amplitud use tucker format second modifi function use evalu correct give exact result exact amplitud less suscept error result aforement compress show theoret numer comput cost propos method scale seventh power system size use refer result set small molecul method calibr deliv relat accuraci percent energi correct illustr potenti theori calcul isomer energi ortho meta benzyn c h barrier height cope rearrang bullvalen c h method retain near black box natur convent coupl cluster formal depend one addit paramet control accuraci
|
D011789;D010984
|
T196;T170
|
36,314,724
|
oesophag ruptur right pneumonectomi case report oesophag ruptur pneumonectomi rare manag remain signific challeng current case report describ patient underw right pneumonectomi right central squamous cell carcinoma third day oper food residu observ thorac tube consid oesophag ruptur surgeri perform intraop oesophag ruptur observ intermitt sutur perform unfortun oesophag pleural fistula develop anti infect treatment chest drainag thorac irrig nutrit support stent implant use oper patient recov smooth discomfort eat oesophag ruptur pneumonectomi extrem rare treatment difficult opinion surgic repair key treatment oesophag ruptur oesophag pleural fistula occur enhanc nutrit adequ irrig drainag stent implant critic factor
|
D004937;D002294
|
T191;T190
|
36,314,718
|
total endoscop robot assist tricuspid valv repair neochord describ techniqu total endoscop robot assist tricuspid valv repair neochord annuloplasti high risk obes patient
|
D014262;D065287;D006348;D019918;D058385
|
T061;T047
|
36,314,709
|
histolog timelin delay hypersensit reaction covid pfizer booster year old man present worsen bilater rash leg arm day receiv bntb mrna covid pfizer vaccin booster develop burn palm day receiv booster day observ signific edema finger palm addit thin erythemat papul forearm day develop edema bilater dorsal feet thin erythemat plaqu shin state rash prurit rash follow first two dose pfizer vaccin deni histori skin diseas autoimmun diseas allergi physic examin reveal multipl thin erythemat papul coalesc thin plaqu flexor forearm thin erythemat plaqu dorsal feet figur three mm punch biopsi perform left flexor forearm biopsi carri papul present differ length time papul biopsi site b c present approxim hour hour hour respect figur
|
D000086382;D006968
|
T047;T046;T067
|
36,314,708
|
gingiv recess unusu oral present morphea en coup de sabr year old woman present year histori linear lesion lip experienc pain esthet complaint person famili histori otherwis unremark histori photosensit raynaud phenomenon arthralgia dri eye fever trauma exposur irradi
|
D012594;D005889;D010787
|
T047;T046;T037
|
36,314,707
|
sporothrix brasiliensi causat agent dissemin sporotrichosi aid year old woman live metropolitan area rio de janeiro abandon acquir immun defici syndrom aid therapi year prior admit hospit due weight loss cough fever week dermatolog examin establish normochrom papul molluscum like central umbil face figur hand erythema infiltr oral caviti figur desquam patch leg ulcer right calcaneus figur cd cell count cell mm direct mycolog examin cultur sever agent perform mycolog cultur done skin sputum grew sporothrix week admiss figur
|
D013175;D013174;D000163
|
T047;T004
|
36,314,706
|
porokeratot variant lichen planus year old woman present mild itchi brownish black plaqu last year lesion first appear upper back follow involv face upper arm within month individu lesion began small papul gradual evolv small annular bare palpabl plaqu system complaint photosensit histori intak prolong medic cutan examin reveal multipl well demarc hyperpig oval round plaqu photo expos area includ face bilater arm upper trunk measur cm size figur b dermatoscop examin establish roll thread doubl margin border central atrophi brownish reticular background multipl brownish black globul dark lacuna also observ figur c wickham striae view combin clinic present dermatoscop find indic provision clinic diagnosi dissemin superfici porokeratosi biopsi perform upper back reveal hyperkeratot epidermi mild lymphocyt exocytosi spongiosi pigmentari incontin coronoid lamina reveal patholog section examin includ deeper section repeat biopsi clinic morpholog dermatoscop featur patholog consid compat diagnosi porokeratot variant lichen planus lp patient counsel start topic steroid fluticason regular follow
|
D017499;D008010;D017495;D057896
|
T019;T047;T046;T020
|
36,314,705
|
sweet syndrom garb cellul continu diagnost conundrum neutrophil dermatos year old woman present emerg depart day histori pain reddish skin lesion leg high grade fever prior medic surgic histori unremark deni histori similar lesion take medic prior onset lesion
|
D016463;D003872
|
T047
|
36,314,703
|
chronic urticaria thorough histori physic examin vital accur diagnosi chronic urticaria extend laboratori test rare yield clinic signific action find henc recommend patient experi symptomat relief follow treatment h antihistamin omalizumab cyclosporin eventu spontan remiss
|
D000080223;D014581;D018926
|
T121;T047
|
36,314,698
|
examin util cysteamin treatment melasma current perspect melasma chronic cutan condit affect appear patient also immens psychosoci impact patient qualiti life although mani treatment option current avail singl univers treatment regimen work patient signific attent recent focus develop use topic treatment lighten dark patch associ melasma one ingredi receiv grow attent recent year cysteamin work sever mechan influenc melanogenesi pathway commentari review inform topic ingredi offer relev clinic insight
|
D003543;D008548
|
T033;T121;T047;T109
|
36,314,697
|
pediatr hospit atop dermat unit state characterist associ atop triad atop dermat ad one common skin disord pediatr patient mani patient ad also asthma andor allerg rhiniti combin constitut atop triad studi character us pediatr patient hospit primari diagnosi ad eczema ad e determin characterist associ coexist addit diagnos triad retrospect analysi perform includ multivari logist regress model data nation inpati sampl patient met inclus criteria n consist predomin toddler male gender white race belong household lowest quartil annual incom cover medicaremedicaid mean length stay total charg signific higher patient ad e plus asthma andor allerg rhiniti compar patient ad e alon multivari analysi age sex signific associ presenc addit atop condit mid childhood group highest likelihood compar infant girl lower likelihood compar boy understand characterist associ addit atop condit children ad e well healthcar dispar popul may yield earli intervent enhanc care improv resourc alloc
|
D003876;D001249;D065631
|
T047
|
36,314,696
|
anti pd agent treatment cutan squamous cell carcinoma cutan squamous cell carcinoma scc second common type skin cancer account approxim nonmelanoma skin cancer nmsc although major cutan scc lesion treat success surgic excis cryotherapi electrodess moh micrograph surgeri local advanc scc patient either inoper metastas patient treatment challeng due limit option review literatur describ mechan anti pd agent cancer therapi current pd blockad immunotherapi trial cutan scc current cemiplimab anti pd agent approv food drug administr treatment local advanc metastat scc review describ anti pd agent pembrolizumab nivolumab depict promis effect advanc scc result reduct tumor size minim advers effect immunotherapi target pd pd l axi must consid advanc cutan scc patient refractori first line procedur treatment option
|
D002294;D012878
|
T191
|
36,314,695
|
monkeypox outbreak women children patient januari juli world health organ receiv report laboratori confirm patient monkeypox predomin men occur multi countri outbreak virus period women six children report infect monkeypox virus although infect number women children small data worrisom young children pregnant women increas risk sever outcom monkeypox one infant alreadi hospit intens care london england data regard monkeypox outbreak also indic healthcar worker diagnos monkeypox although still investig whether infect due occup exposur three death monkeypox report monkeypox outbreak special focus present monkeypox infect involv women children
|
D045908;D016273
|
T047;T037
|
36,314,686
|
kdigo guidelin blood pressur manag chronic kidney diseas base weak evid recent publish kidney diseas improv global outcom kdigo guidelin blood pressur bp manag chronic kidney diseas ckd recommend target systol bp mm hg adult hypertens ckd recommend controversi base weak evid deriv primarili ckd subgroup analysi singl random control trial swedish societi nephrolog recommend bp target mm hg patient provid treatment well toler bp target mm hg recommend patient ckd
|
D051436;D006973
|
T047
|
36,314,685
|
hip pain hip pain difficult assess structur diagnost import facilit evalu hip pain recommend divid hip pain intra extra articular pain latter divid differ entiti plain radiograph warrant referr orthopaed specialist furthermor need magnet reson imag mri decid orthopaed surgeon
|
D006621;D009985
|
T091;T030
|
36,314,659
|
oscillatori reaction activ singl cuprous oxid microparticl report use dark field microscopi dfm simpl low cost imag platform visual resolv kinet singl cuprous oxid cu microparticl remov real time manner unexpect find redox reaction cu microparticl oscil reaction time specif oscillatori behavior singl cu microparticl reduct show larg particl particl variabl also depend upon pressur cu facet combin dfm imag spectroscop scan electron microscopi densiti function theori studi uncov cu gradual transform copper nitrat hydroxid cu oh oscillatori reaction attribut cyclic format structur collaps cu oh present find open altern avenu probe structur perform relationship anticip benefit creation function materi air purif
|
D003300;D009585
|
T123;T121;T131;T196;T197
|
36,314,627
|
histolog timelin delay hypersensit reaction covid pfizer booster year old man present worsen bilater rash leg arm day receiv bntb mrna covid pfizer vaccin booster develop burn palm day receiv booster day observ signific edema finger palm addit thin erythemat papul forearm day develop edema bilater dorsal feet thin erythemat plaqu shin state rash prurit rash follow first two dose pfizer vaccin deni histori skin diseas autoimmun diseas allergi physic examin reveal multipl thin erythemat papul coalesc thin plaqu flexor forearm thin erythemat plaqu dorsal feet figur three mm punch biopsi perform left flexor forearm biopsi carri papul present differ length time papul biopsi site b c present approxim hour hour hour respect figur skinm
|
D000086382;D006968
|
T047;T046;T067
|
36,314,626
|
gingiv recess unusu oral present morphea en coup de sabr year old woman present year histori linear lesion lip experienc pain esthet complaint person famili histori otherwis unremark histori photosensit raynaud phenomenon arthralgia dri eye fever trauma exposur irradi skinm
|
D012594;D005889;D010787
|
T047;T046;T037
|
36,314,625
|
sporothrix brasiliensi causat agent dissemin sporotrichosi aid year old woman live metropolitan area rio de janeiro abandon acquir immun defici syndrom aid therapi year prior admit hospit due weight loss cough fever week dermatolog examin establish normochrom papul molluscum like central umbil face figur hand erythema infiltr oral caviti figur desquam patch leg ulcer right calcaneus figur cd cell count cell mm direct mycolog examin cultur sever agent perform mycolog cultur done skin sputum grew sporothrix week admiss figur skinm
|
D013175;D013174;D000163
|
T047;T004
|
36,314,624
|
porokeratot variant lichen planus year old woman present mild itchi brownish black plaqu last year lesion first appear upper back follow involv face upper arm within month individu lesion began small papul gradual evolv small annular bare palpabl plaqu system complaint photosensit histori intak prolong medic cutan examin reveal multipl well demarc hyperpig oval round plaqu photo expos area includ face bilater arm upper trunk measur cm size figur b dermatoscop examin establish roll thread doubl margin border central atrophi brownish reticular background multipl brownish black globul dark lacuna also observ figur c wickham striae view combin clinic present dermatoscop find indic provision clinic diagnosi dissemin superfici porokeratosi biopsi perform upper back reveal hyperkeratot epidermi mild lymphocyt exocytosi spongiosi pigmentari incontin coronoid lamina reveal patholog section examin includ deeper section repeat biopsi clinic morpholog dermatoscop featur patholog consid compat diagnosi porokeratot variant lichen planus lp patient counsel start topic steroid fluticason regular follow skinm
|
D017499;D008010;D017495;D057896
|
T019;T047;T046;T020
|
36,314,623
|
sweet syndrom garb cellul continu diagnost conundrum neutrophil dermatos year old woman present emerg depart day histori pain reddish skin lesion leg high grade fever prior medic surgic histori unremark deni histori similar lesion take medic prior onset lesion skinm
|
D016463;D003872
|
T047
|
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