Javtor/biomedical-topic-categorization-validation

PMID int64 35.7M 36.4M	Title/Abstract stringlengths 22 8.78k	MeshTerms stringlengths 7 101	SemanticTypes stringlengths 4 64
36,308,382	snp rs ros dcbld locus signific associ lung cancer risk poor surviv indian popul receptor tyrosin kinas rtk relev therapeut target treatment lung cancer germlin suscept variant influenc rtks may provid new insight regul rs locat genom interv two rtk gene rosdcbld ros alter implic lung carcinogenesi treatment respons latter remain poor understood	D008175;D014029	T191;T048
36,308,381	identif malign pap smear sampl use cgb nop gene methyl marker although various improv made report papanicolaou pap test recent year remain sever challeng yet address term determin standard methodolog categor atyp squamous cell undetermin signific asc us	D065309;D018290;D002583;D030361	T033;T047;T191;T025
36,308,380	anti prolif effect potenti lsdcorest inhibitor base molecular dynam model treatment sh syy neuroblastoma cancer cell line lysin specif demethylas demethylas enzym remov methyl group histon hkme hkme express mani cancer imped differenti contribut cancer cell prolifer cell metastasi invas associ inferior prognosi lsd associ corepressor protein corest util tetrahydrofol cofactor accept ch demethyl process fact cofactor best bound activ site inspir us explor interact lsdcorest enzym complex util molecular dynam simul aid design novel potent inhibitor	D056004;D009447	T066;T191;T044
36,308,379	role efna snp rs tumorigenesi metastasi colorect cancer bioinformat analysi hrm snp genotyp verif colorect cancer preval diseas poor prognosi known heterogen diseas mani differ clinic symptom molecular profil present studi aim systemat evalu associ snps mirna bind site target gene involv crc angiogenesi epitheli mesenchym transit cytoskeleton organ tumorigenesi metastasi crc	D015179;D020641	T191;T086
36,308,378	relaps childhood acut lymphoblast leukemia experi singl tertiari center thailand outcom relaps childhood acut lymphoblast leukemia develop countri improv time result risk adapt minim residu diseas direct therapi hematopoiet stem cell transplant immunotherapi studi examin surviv relaps childhood resourc limit countri therefor studi aim assess prognost factor surviv outcom relaps childhood major tertiari center southern thailand	D054198;D018380	T061;T191
36,308,377	cancer stem cell prognost biomark therapeut target use curcumin piperin extract multipl myeloma multipl myeloma mm hematolog bone marrow malign treat usual fatal medic resist major caus relaps due cancer stem cell cscs result studi aim identifi multipl myeloma cancer stem cell mmcscs bone marrow twelv mm patient patholog complet respons pcr chemotherapi investig potenti effect curcuminpiperin cp extract anti mmcscs treatment twenti newli diagnos patient	D009101;D003474	T121;T191;T130;T109
36,308,376	correl among kras mutat microsatellit instabl f fdg uptak colon cancer studi aim evalu correl maximum standard uptak valu suvmax kirsten ras sarcoma viral oncogen kras mutat microsatellit instabl msi status colon cancer	D019788;D003110	T191;T130;T109
36,308,375	import skin health promot children care makeup use skin cancer prevent numer pathogen complic affect skin prevent skin cancer microbi diseas dermal irrit anaphylaxi context correct use skin product includ sunscreen child makeup import promot skin health prevent advers health condit	D007722;D012878	T053;T191
36,308,374	investig role glutathion transferas gene histopatholog molecular subtyp gene gene interact suscept breast carcinoma ethnic north indian popul breast cancer bc genet clinic heterogen diseas includ complex interact gene gene gene environ compon studi aim explor whether glutathion transferas gsts gene polymorph role bc suscept evalu frequenc four subtyp bc base molecular classif follow microscop histolog analysi studi grade invas ductal carcinoma idc	D001943;D020022	T032;T191
36,308,373	constip sever qualiti life among patient cancer receiv prophylact laxat quasi experiment studi prophylact laxat associ decreas incid opioid induc constip among patient cancer studi aim evalu effect earli prophylact laxat therapi sever constip qualiti life among patient cancer receiv opioid	D000079689;D009369	T184;T047;T191
36,308,372	metabolit profil biolog activ assess casuarina equisetifolia bark incorpor gold nanoparticl casuarina equisetifolia bark rich various activ metabolit select studi due limit synthet antioxid advers side effect present studi aim enhanc effici effect extract incorpor gold nanoparticl au nps	D006046;D053768	T121;T196;T073
36,308,371	tnf allel carrier induc develop chronic lymphocyt leukemia sudanes popul earlier age sever studi perform investig associ tnf g asnp cll suscept howev result inconsist studi aim investig associ tnf g asnp tnf gene cll risk sudanes popul correl genotyp clinicopatholog featur	D014409;D015451	T129;T191;T116
36,308,370	line alu methyl hrhpv associ precancer cervic sampl studi conduct determin global dna methyl pattern cervic cell cytolog identifi atyp squamous cell unknown signific ascus normal lsil hsil histopatholog result	D065309;D011230;D002583;D030361	T033;T047;T191;T025
36,308,369	effect antimicrobi peptid fox lncrna ptcsc gene express colorect cancer crc normal cell innat immun system compon antimicrobi peptid amp exert various effect anticanc properti studi aim evalu amp anticanc effect colorect cancer crc cell express fox lncrna ptcsc gene	D062085;D015179	T123;T191;T114
36,308,368	cigarett display regul point sale pos impact cigarett sale studi aim determin impact cigarett display set cigarett sale store semarang citymethod research conduct august octob use quasi experiment studi approach conduct set cigarett display method cigarett display open day store cigarett display cover cloth pre post intervent period day respect five store cigarett display hidden pre post intervent period day respect three store cigarett sale record base mani pack stick sold per day visit store made everi two three day without prior notif store owner ensur cigarett display appropri record data sale data descript evalu use pair test confid level result result show one hidden cigarett display store r experienc signific decreas sale three hiddencov display store less signific decreas cigarett sale four hiddencov display store nt declin cigarett sale averag declin cigarett consumpt store packsday analysi sale per day pair pre post intervent test store cover display show differ pre post intervent sale store hidden display show differ conclus thus cover display affect store cigarett sale store hidden display show differ sale	D062789	T131;T073;T109
36,308,367	triplet folfoxiri versus doublet folfox folfiri regimen first line treatment metastat colorect carcinoma prospect phase ii random control trial outcom treatment metastat colorect cancer mcrc still unsatisfactori sever trial approv upfront treatment triplet regimen includ fluorouracil leucovorin irinotecan oxaliplatin improv outcom patient metastat diseas compar standard doublet regimen object studi evalu impact upfront treatment triplet folfoxiri regimen oncolog outcom respons rate surviv patient toler comparison standard doublet regimen	D015179	T191
36,308,366	full complianc adjuv endocrin therapi associ higher diseas free surviv hormon receptor posit negat chines breast cancer patient first tumor recurr character complianc status adjuv endocrin therapi aet relationship diseas free surviv dfs hormon receptor posit hr negat chines breast cancer bc patient first tumor recurr	D001943	T191
36,308,365	pki dual stain posit human papillomavirus dna test predict diagnosi abnorm cervic lesion northeastern thai women cervic cancer screen effect reduc new cervic cancer case includ thailand abnorm result subsequ refer colposcopi avoid unnecessari colposcopi effici triag still need valid studi aim investig overal posit cytolog base screen hpv detect pki dual stain evalu differ triag strategi predict diagnosi abnorm cervic lesion northeastern thailand	D018290;D002583;D030361;D065309;D000081483;D052685	T025;T191;T033;T005;T047
36,308,364	associ prestor smartphon monitor physic activ risk hpv infect cervic cancer studi determin preval hpv non vaccin women east china associ prestor smartphon monitor physic activ risk human papillomavirus hpv infect cervic cancer	D030361;D002583	T047;T191
36,308,363	diffus weight mri non invas diagnost tool rectal cancer aggress correl ki express tumor tissu appar diffus coeffici adc suggest prognost marker rectal carcinoma rc howev report data inconsist present studi aim assess relat adc valu ki express index patholog paramet egyptian rc patient	D038524;D012004	T060;T191
36,308,362	low dose berberin suppress cholangiocarcinoma cell progress multi kinas inhibitor berberin bbr natur isoquinolin alkaloid possess divers pharmacolog properti anti cancer effect demonstr mani vitro vivo studi studi inhibitori effect molecular mechan low dose bbr emt induc cell migrat invas capabl cholangiocarcinoma cca cell line demonstr	D001650;D001599;D018281;D000970	T121;T191;T109
36,308,361	surviv analysi clinic outcom paclitaxel carboplatin versus carboplatin gemcitabin patient advanc stage non small cell lung cancer singl center cohort studi palliat chemotherapi use platinum base doublet chemotherapi recommend one standard treatment patient advanc stage non small cell lung cancer nsclc negat egfr mutat studi aim compar clinic outcom patient treat paclitaxel carboplatin pc treat carboplatin gemcitabin cg	D002289;D008175	T191
36,308,360	role mirna foxo express breast cancer evalu role foxo mrna mi rna p express level bc patient	D001943;D035683	T123;T191;T114
36,308,359	estim neural tissu mobil breast cancer survivor lymphedema lymphedema breast cancer survivor common condit progress may lead entrap neuropathi lymphedema accumul fluid due remov lymph node caus stretch nerv fibr within skin compress top nerv bundl lead nerv entrap increas neural mechanosensit function impair shoulder protect neural respons movement traction	D001943;D000073116;D008209	T201;T191;T047;T046;T101
36,308,358	immun relat cerna network prognosi cervic cancer immunotherapi gain attent includ one treatment strategi cancer patient howev molecular mechan immun relat gene affin cervic cancer progress remain unclear studi develop immun relat compet endogen rna cerna network assess tumour infiltr immun cell toward prognosi cervic cancer	D062085;D002583;D035683	T123;T191;T114
36,308,357	relat work abil return work among iranian cancer survivor cancer diseas known disrupt person abil inflict physic psycholog financi social complic person therebi challeng individu return work aim studi investig abil cancer patient work return work	D000073116;D009369	T201;T191;T101
36,308,356	associ pikca mutat blood tumor infiltr lymphocyt peruvian breast cancer patient evalu relationship circul tumor dna ctdna presenc tumor featur includ tumor infiltr lymphocyt til level peruvian breast cancer patient	D000074141;D009369	T191;T114
36,308,355	efficaci short hydrat intermedi high dose cisplatin base chemotherapi outpati shortci trial support data exist concern short hydrat prevent cisplatin induc nephrotox howev studi exist data remain limit compris most retrospect data therefor studi would like evalu efficaci short hydrat use prospect cohort studi	D000970;D064420	T121;T046;T037;T109
36,308,354	studi preoper neutrophillymphocyt nlr plateletlymphocyt ratio plr predict factor endometri cancer evalu predict factor serum inflammatori marker malign potenti endometrium	D009504;D016889	T191;T025
36,308,353	mesenchym stem cell treatment aggrav tumor growth regardless rout administr vivo studi clarifi effect mscs cancer growth detect whether rout administr either local insid tumor tissu system could affect outcom treatment	D062085;D059630;D045164	T061;T123;T025;T114
36,308,352	risk factor diagnosi lung cancer poland larg scale popul base case control studi lung cancer one common dead malign neoplasm current one main caus cancer death worldwid studi aim identifi evalu patient characterist demograph lifestyl factor associ lung cancer diagnosi	D008175;D029424;D014376	T047;T191
36,308,351	comparison classif success rate differ machin learn algorithm diagnosi breast cancer identifi machin learn ml algorithm success predict diagnos breast cancer accord accuraci rate	D001943	T191
36,308,350	effect replac wharton acellular jelli fbs express megakaryocyt linear marker hematopoiet stem cell cd anim environ growth stem cell caus transmiss diseas immun problem recipi accord replac environ healthi environ least human resourc essenti one media use altern anim serum wharton acellular jelli awj therefor studi intend replac fbs wharton jelli investig effect express megakaryocyt relat gene marker stem cell	D008533;D059631	T018;T025
36,308,349	estim cancer treatment cost common type cancer separ pocket government cost afghanistan object studi estim cost cancer treatment servic common type cancer breast esophag colorect stomach lung public sector patient studi cross section studi conduct use medic record patient regist jamhuriyat hospit preval base approach use estim cost five major cancer type data patient elig includ analysi consid cost servic obtain averag cost privat hospit kabul also cost convert us dollar use exchang rate usd equal afn data analyz use ms excel program total number patient type cancer femal age group year illiter common cancer base cancer treatment servic cost health servic breast cancer follow esophagus colorect stomach lung moreov common cancer base cancer treatment servic cost health servic cancer patient need breast cancer follow esophagus colorect stomach lung moreov total cost cancer treatment us patient paid usd pocket cost cancer treatment servic common type cancer high consider portion paid patient need govern pay attent provis servic increas center provid servic exist facil also support intern communiti process enabl peopl access servic reduc econom burden patient	D001943;D015179	T191
36,308,348	measur occup fatigu among higher middl manag special cancer center covid pandem studi aim measur occup fatigu level describ sourc consequ occup fatigu among middl higher manag intern special cancer center covid pandem	D000086382;D009369	T047;T191;T067
36,308,347	valid immun status questionnair isq indonesian bahasa languag simpl assess perceiv immun status studi aim determin whether isq use assess immun status daili clinic practic indonesia translat questionnair bahasa analyz valid reliabl	D007802	T171
36,308,346	evalu cytochrom pe mrna express effect antioxid defens cell toxic print worker cytochrom pe cype metabol environment toxin howev compound metabol produc oxid stress caus cell toxic sometim transform	D016273;D000073888	T123;T037;T114
36,308,345	assess cell cycl induct apoptosi shiga like toxin produc escherichia coli h td breast cancer cell use flow cytometri low general toxic tumor express globotriaosylceramid gb shiga like toxin produc e coli propos anti cancer therapi specif target studi aim determin potenc local strain e coli h isol human cattl new breast cancer therapi analyz cell cycl inhibit apoptosi induct	D019453;D001943;D004927	T047;T007;T191
36,308,344	associ handgrip strength qualiti life breast cancer survivor systemat review meta analysi handgrip strength hgs indic general muscular strength cancer patient act relev marker associ mortal health studi aim evalu associ peripher muscl function health relat qualiti life hrqol breast cancer bc survivor	D000073116;D001943	T201;T191;T101
36,308,280	predictor sirolimus pharmacokinet variabl identifi use nonlinear mix effect approach systemat review sever sirolimus srl popul pharmacokinet poppk conduct explain pharmacokinet variabl result vari across studi thus conduct systemat review summar signific predictor influenc srl pharmacokinet variabl moreov discrep model methodolog across studi also review discuss four databas pubm cinahl complet scienc direct scopus systemat search pico framework use identifi elig studi conduct human employ nonlinear mix effect strategi base inclus exclus criteria studi includ srl pharmacokinet explain use compart model one studi assess model use extern approach rest employ basic advanc intern approach signific covari influenc srl pharmacokinet bodyweight age cypa polymorph gender bsa height cyclosporin dose trough concentr triglycerid total cholesterol hematocrit albumin aspart aminotransferas alanin aminotransferas total bilirubin bodyweight age cypa polymorph three identifi signific predictor srl clearanc review summar signific predictor predict srl clearanc subsequ use individu srl mainten dose howev poppk model select predict base resembl popul characterist target popul use conduct model moreov predict model target popul assess implement clinic practic	D020123;D016030	T061;T121;T195;T109
36,308,265	strive excel subspecialti medic train nigeria th theophilus oladapo ogunlesi lectur solid foundat laid prof theophilus oladapo ogunlesi found father nation postgradu medic colleg nigeria npmcn consist achiev mandat produc specialist medic practition nigeria ever chang world requir nigeria critic mass subspecialist tackl various old emerg ailment afflict citizenri subspecialist train popular among nigerian specialist yet subspecialist crave train nigerian born sub specialist diaspora will assist train left polici maker captain train institut seiz chanc move us forward view improv current embarrass low number subspecialist nigeria npmcn herebi beckon take lead combin excel relev	D007396	T065;T097
36,308,264	hoars nigerian tertiari health facil preval aetiolog predispos factor determin preval aetiolog predispos factor patient present hoars usmanu danfodiyo univers teach hospit sokoto	D006685;D005764	T184;T047
36,308,263	vascular injuri aetiolog present manag outcom tertiari hospit lago nigeria vascular injuri lead haemorrhag shock distal limb ischaemia especi arteri injuri life threaten state mandat urgent evalu intervent save life limb treatment aim restor blood flow replac lost blood within golden hour stabilis cardiovascular haemodynam avert irrevers ischaem damag aim studi analys clinic profil vascular injuri manag outcom institut	D057772	T037
36,308,262	predictor caus hospit matern death within h admiss tertiari hospit south western nigeria retrospect cohort studi effici comprehens emerg obstetr care cemoc consider reduc burden matern mortal mm nigeria inform risk matern death within h admiss reflect qualiti cemoc offer	D063130;D014597;D046110;D018805	T047;T040;T046
36,308,261	socio demograph factor influenc measur cognit function earli adolesc student abuja nigeria brain earli adolesc period undergo enhanc chang radic reorganis neuron network lead improv cognit capac complex interplay exist environ genet influenc outcom intellectu capabl therefor aim evalu relationship socio demograph variabl measur cognit function intellig quotient iq academ perform earli adolesc	D007360;D013334	T081;T098;T041
36,308,260	evalu effect nutrit versus non nutrit pacifi adjunct local anaesthesia male neonat circumcis use plastibel techniqu prospect randomis control studi male circumcis common surgic procedur worldwid often carri religi cultur medic public health reason common perform neonat period mani studi shown pain common intra post oper complic ensur proper analgesia procedur mani surgeon opt use pacifi adjunct anaesthesia neonat circumcis aim studi compar nutrit pacifi nps versus non nps nnps adjunct local anaesthesia male neonat circumcis use plastibel techniqu	D002944	T061
36,308,259	non covid uptak person protect equip rule complianc amongst industri worker kano nigeria everi workplac got hazard mani differ form rang sharp fall object chemic infect nois lot potenti danger situat occup safeti health administr mandat employ protect employe potenti danger workplac hazard person protect equip ppe play import role prevent ensur health safeti amongst industri worker studi aim determin use ppe rule complianc amongst industri worker kano state	D016272;D000067393	T078;T091;T073
36,308,258	willing pay covid vaccin oneself one child among individu attend tertiari care centr west bengal india free cost suppli could meet demand coronavirus diseas covid vaccin india govern approv inject option price aim determin much money individu would will pay covid vaccin children assess factor determin	D000086663;D000086382	T200;T047;T067
36,308,257	accept appropri feasibl webinar strengthen research capac covid era nigeria challeng pose covid pandem necessit increas use onlin virtual train platform object studi assess accept appropri feasibl virtual space strengthen research capac nigeria	D000086382	T047;T067
36,308,256	nigeria nation health insur author act implic toward achiev univers health coverag nation health insur scheme nhis face sever inher system drawback toward achiev univers health coverag nigerian led sign new nation health insur author act nhia articl highlight benefit nhia discuss possibl challeng way forward implement narrat review past literatur search pubm medlin african journal onlin goggl conduct total public initi retriev follow data triangul final use author also includ experi nhia address shortcom previous nhis howev would still face sever challeng implement low govern fund prioriti health shortag healthcar worker poor healthcar coverag well problem enforc mandat nigerian enrol impend constraint must surmount stakehold must involv ensur act accomplish aim	D019472;D009313	T078;T058;T170
36,308,255	recurr tumor ameloblastoma clinicopatholog featur diagnost outcom ameloblastoma benign epitheli odontogen tumor tendenc recurr recurr tumor could behav unpredict atyp microscop chang	D000564;D009808	T191
36,308,253	soft tissu sarcoma arm oncosurg reconstruct challeng case report soft tissu sarcoma sts rare tumor may occur upper extrem present delay slow growth lack symptom lesion discov via physic radiolog examin definit diagnosi conduct histopatholog present case year old man swell dorsum arm nocturn hyperhidrosi weight loss radiolog examin reveal possibl malign metabol activ left axillari lymph node tumor excis defect cover use pedicl myocutan latissimus dorsi flap distal portion muscl attach remnant tricep brachii tendon postop histopatholog reveal high malign sts patient remain relaps free regimen adjuv chemotherapi satisfactori aesthet result modest elbow extens evid month follow proper manag upper extrem sts crucial prevent recurr metastasi	D017695;D019651;D012509	T061;T191;T037
36,308,252	cumul inflammatori burden caus multipl complic success pelvic surgeri advanc ovarian cancer vesicovagin rectovagin fistula may develop pelvic metastasi ovarian carcinoma purul discharg vagina result frequent vagin urinari tract infect trigger chronic inflamm incapacit symptom creat serious medic psychosoci problem result low self esteem qol studi present metastat ovarian cancer case admit bilater nephrostomi nonfunct colostomi high volum recto vesicovagin fistula debulk frequent urinari tract infect system inflammatori respons syndrom surgeri perform success howev deal complic electrolyt imbal wound infect continu sir cumul inflammatori burden caus advanc carcinoma complic creat serious medic psychosoci problem manag patienc	D014719;D002277;D010051	T191;T190
36,308,251	endobronchi actinomycosi case report extrem rare diseas slow cours actinomycosi high mortal risk proper treat pulmonari actinomycosi clinic radiolog analog tuberculosi foreign bodi aspir lung abscess lung cancer therefor often caus misdiagnosi delay diagnosi year old male patient follow diagnosi chronic obstruct pulmonari diseas copd lung adenocarcinoma admit outpati clinic complaint chronic cough chest ct cavitari lesion upper lobe right lung observ sputum acid fast bacilli afb negat consecut time fungal direct examin negat growth mycobacterium cultur fungal cultur flexibl bronchoscopi reveal rais hard white color lesion mucosa obliter apic anterior segment bronchial entranc right lung upper lobe diagnosi actinomycosi made sulfur granul seen patholog result biopsi lavag detect sulfur granul biopsi essenti diagnosi actinomycosi near complet respons usual obtain long term antibiot treatment altern method surgic debrid consid case respond antibiot treatment	D000196;D008171	T047
36,308,250	effect differ polymer time color chang transluc paramet surfac hard bulk fill resin composit polymer play import role optic mechan properti resin composit materi	D003188;D003764	T122
36,308,249	relationship crpalbumin ratio level prognosi pregnant covid patient c reactiv protein crp albumin ratio car one new tool assess sever inflamm use determin clinic sever prognosi mani diseas	D002097;D000086382	T129;T047;T116;T067
36,308,248	profil insulin resist pregnant women late third trimest nigeria descript cross section report exagger level insulin resist ir associ poor pregnanc outcom identifi affect women may forestal outcom report ir predictor among pregnant women nigeria	D007333;D006943;D006973;D016640	T033;T047;T046
36,308,247	subclin hypothyroid children idiopath childhood nephrot syndrom tertiari institut south west nigeria hypothyroid children nephrot syndrom ns often attribut prolong loss thyroxin bind globulin thyroid hormon alongsid protein urin histor associ steroid resist ns alon howev recent evid support fact subclin hypothyroid sch occur even children steroid respons ns complic weight gain hypercholesterolemia delay growth delay puberti depress could result hypothyroid erron attribut ns effect steroid use treatment incident salt intak major form dietari iodin often restrict children ns possibl exacerb under hypothyroid state	D009404;D007037;D007455	T123;T047;T121;T196
36,308,246	allerg rhiniti indic otiti media effus children seen aminu kano teach hospit kano allerg rhiniti ar multifoc ige mediat type hypersensit reaction involv nasal mucosa character excess sneez wateri rhinorrhea nasal itch nasal stuffi eye itch tympanometri simpl rapid object test easili carri use tympanometri clinic set improv detect middl ear effus middl ear abnorm ar found one predispos factor develop otiti media effus ome children	D010034;D010033;D065631;D004427	T047
36,308,245	tissu doppler echocardiograph evalu cardiac function children mucopolysaccharidosi type iii diseas mucopolysaccharidosi type iii mps iii extrem rare group diseas among mps type recent year studi presenc import cardiac involv mps iii patient type mps	D015150;D009083	T060;T047
36,308,244	perfus ndex pleth variabl index titl earli ndicat brachial plexus block studi evalu perfus index pi pleth variabl index pvi success pi pvi block patient undergo brachial plexus limit quit inadequ	D065527;D001917	T061;T023
36,308,243	measur differ diaper paramet evalu postcircumcis bleed signific nfant health evalu circumcis bleed depend visual chang diaper diaper differ product featur absorb capac appar chang diaper may vari accord absorb capac may parallel amount bleed signific visual differ occur patient hemodynam may impair	D003963	T047
36,308,242	assess skelet relationship cleft palat without cleft lip cone beam comput tomographi studi pakistani popul understand differ skelet relationship orofaci cleft use cone beam comput tomographi cbct may eventu lead develop better diagnosi treatment protocol facial deform	D002971;D002972	T019
36,308,241	clinic radiolog outcom lock plate osteosynthesi distal metadiaphys tibial fractur accord sever comminut varus reduct would prefer lower clinic outcom optim treatment distal tibial fractur remain matter debat nonetheless plate osteosynthesi produc favor result intramedullari stabil aspect align restor	D013978;D018460	T037
36,308,240	chang surfac characterist permeabl human enamel subject radiat therapi radiat relat cari complex destruct lesion lead uncompromis damag enamel dentin patient suffer head neck cancer manag radiotherapi	D014070	T023
36,308,239	anti microbi efficaci root canal prepar decidu teeth manual rotari file random clinic trial pulpectomi erad microb primari root canal accomplish biomechan prepar could carri either manual rotari instrument	D018915;D014094	T061;T023
36,308,238	possibl predict outcom endovascular thrombectomi hyperdens middl cerebr arteri sign time first admiss hyperdens middl cerebr arteri sign hmcas admiss non contrast comput tomographi ncct well character phenomenon acut ischem stroke	D020521;D000083242;D002545	T047;T046
36,308,237	new perspect relationship anchorag palat morpholog three dimension digit model analysi tooth movement general analyz two dimens cephalometr radiograph nowaday digit model analysi harm effect patient use evalu palat morpholog coron tooth movement comfort easi way	D008437;D008312	T023;T190
36,308,236	abo rh blood type clinic consequ covid infect suffici evid show relationship blood type sever sever acut respiratori syndrom coronavirus sar cov infect studi plan investig effect abo blood group clinic outcom sar cov infect	D000086382	T047;T067
36,308,235	clinic awar knowledg breast cancer relat lymphedema among group psychiatrist turkey onlin survey point view role physiatrist import clinic care breast cancer relat lymphedema bcrl patient set manag rehabilit strategi	D001943;D008209;D011570	T091;T191;T097;T047;T046
36,308,234	impact covid pandem academ train psychosoci well undergradu dental student nigeria educ institut nigeria shut long onset covid pandem prevent measur affect dental student academ clinic train	D000086382	T047;T067
36,308,233	serum folat level children epilepsi seen tertiari health care facil north central nigeria children suffer epilepsi maintain antiepilept drug a ensur reason qualiti life drug howev without side effect notabl among interfer metabol folat attend clinic implic megaloblast anemia bleed diathesi	D014635;D004827	T033;T121;T047;T109
36,308,232	thoracoscop repair congenit diaphragmat hernia neonat tip trick learn institut experi congenit diaphragmat hernia cdh anomali signific morbid neonat tradit manag open approach recent trend toward minim invas approach	D065630	T019
36,308,231	effect differ posit unerupt lower third molar teeth fragil mandibular angl finit element analysi mandibular bone largest strongest bone comparison bone face skeleton howev common fractur facial injuri locat fractur mandibl depend various factor relationship impact lower third molar teeth mandibular angl fractur subject mani epidemiolog studi argu risk fractur mandibular angl two four time particular impact partial impact third molar teeth howev effect posit impact tooth mandibular angl fractur clear yet	D014095;D008337	T047;T037
36,308,230	outcom surgic manag symptomat renal angiomyolipoma ibadan nigeria sub saharan africa renal angiomyolipoma commonest benign solid kidney neoplasm though rare clinic practic advent radiolog imag techniqu refin surgic approach techniqu avail mammalian target rapamycin improv outcom cohort patient	D018207;D007680;D006222	T191
36,308,229	build respons healthcar system nigerian experi healthcar system must respons need client entail element digniti confidenti autonomi prompt attent social support basic amen choic provid target toward improv mainten qualiti healthcar consequ improv patient outcom reduc cost	D003695;D012944	T054;T058;T093
36,308,226	dr p v gharpur emin indian pathologist pioneer start oral polio vaccin india dr purushottam vishwanath gharpur emin indian pathologist emeritus professor patholog grant medic colleg bombay pioneer carri first field trial polio vaccin mark begin polio erad program india dr gharpur set exampl take laboratori work field prove laboratori research use better societi mesmer stori dr gharpur life describ paper	D000072142;D011051	T047;T097
36,308,213	primari leiomyosarcoma ovari rare malign incident find primari leiomyosarcoma plms ovari extrem rare tumor compris ovarian tumor ovarian malign primari ovarian sarcoma case report till date year old postmenopaus femal present abdomin pain last month ultrasonographi mri reveal heterogen enhanc solid lobul mass left adnexa abut fundus uterus bowel loop endometri caviti normal ovarian marker ca cea ca hematolog paramet within normal limit ldh near normal iuml specimen sent frozen section diagnosi malign spindl cell lesion ovari render histopatholog ovarian mass reveal intersect fascicl tumor cell consist ovoid spindl shape cell moder amount cytoplasm bizarr atyp cell seen singl dispers small aggreg along brisk mitot activ focal area necrosi hemorrhag also note immunohistochemistri show strong posit smooth muscl actin caldesmon focal posit desmin epitheli membran antigen ema note lesion negat inhibin calretinin cd final diagnosi primari ovarian leiomyosarcoma given base histopatholog immunohistochemistri plms ovari rare incident find postmenopaus women high malign tumor carri poor prognosi henc earli diagnosi surgic treatment cytoreduct improv patient surviv	D007890;D010051	T191
36,308,212	renal hepat chang case envenom snake bite case report review literatur snake bite major health hazard moreov tropic countri densiti snake frequent human contact lack diagnost treatment facil add high morbid mortal organ escap effect envenom heart liver kidney cns local bite site effect snake venom kidney document literatur avail patholog effect envenom human liver lack present case elder male renal hepat manifest envenom	D012909	T037
36,308,211	differenti pediatr cystic nephroma common renal multicyst lesion case report pediatr cystic nephroma rare clinic benign renal tumor pediatr renal cystic lesion complex imag find tumor appear often nonspecif care patholog examin necessari discuss diagnosi pediatr cystic nephroma differenti multicyst dysplast kidney cystic partial differenti nephroblastoma	D007680;D009396;D052177;D021782;D009447	T019;T047;T191
36,308,210	acut pancreat masquerad mesentr growth covid patient case report covid infecti diseas caus sever acut respiratori syndrom coronavirus sar cov common affect respiratori system produc pneumonia like symptom among extrapulmonari manifest involv gastrointestin tract common symptom nausea vomit diarrhea abdomin pain coronavirus act target ace receptor alveoli lung receptor also present organ pancrea affect pancrea well thus caus acut pancreat discuss case year old hypertens male covid present atyp present acut abdomin pain episod vomit laboratori investig inconclus imag find suggest small bowel obstruct perfor thus exploratori laparotomi done mesenter growth found report acut pancreat histopatholog therefor attent paid pancreat involv atyp present covid patient	D000086382;D010195	T047;T046;T067
36,308,209	primari hepat lymphoma diagnost dilemma primari non hodgkin lymphoma liver rare malign report case year old femal present dull ach right hypochondrium decreas appetit sinc month ct scan abdomen pelvi show enlarg liver ill defin soft tissu lesion aris left lobe measur cm suggest primari hepat neoplasm ct scan chest abdomen pelvi whole bodi positron emiss tomographi show involv bone marrow lymph node spleen organ liver function test alpha fetoprotein carcinoembryon antigen level normal serolog negat virus patholog examin favor diagnosi burkitt lymphoma cytogenet studi myc transloc suggest confirm diagnosi sinc ki index near characterist burkitt lymphoma	D002051;D008113	T191
36,308,208	angiomatoid fibrous histiocytoma report two case initi constru sarcoma unusu clinico patholog featur angiomatoid fibrous histiocytoma afh rare soft tissu tumor uncertain differenti low metastat potenti common occur children adolesc young adult involv extrem due rare natur divers present clinic morpholog often misdiagnos becom import correct diagnos lesion given distinct therapeut implic present clinic radiolog patholog find two rare case afh sinc afh rare soft tissu tumor low malign potenti pathologist clinician awar entiti encount soft tissu mass extrem child adolesc accord appropri treatment case	D018219;D051677;D012983	T191
36,308,207	high grade mix neuroendocrin non neuroendocrin neoplasm gastroesophag junction rare case report review literatur mix neuroendocrin non neuroendocrin neoplasm minen recent describ entiti esophagus latest fifth edit classif digest system tumor often difficult patholog diagnosi especi small preoper biopsi herein report case high grade minen gastroesophag junction diagnos squamous cell carcinoma preoper biopsi subsequ high grade minen esophagogastrectomi specimen compris area mucoepidermoid carcinoma larg cell neuroendocrin carcinoma nec report accentu import deeper multisit preoper biopsi manag complet differ minen esophag squamous cell carcinoma	D004938;D000077277;D018358;D018278	T191
36,308,206	giant hyperplast gastric polyp diagnost dilemma gastric hyperplast polyp ghp account major benign gastric polyp ghps cm asymptomat incident detect endoscopi radiolog increas size polyp manifest upper gastrointestin bleed iron defici anemia gastric outlet obstruct goo report unusu case giant ghp simul gastric carcinoma pose diagnost challeng surgeon emphas diagnost role histopatholog year old femal present clinic featur progress goo year endoscopi reveal eccentr prolif lesion antrum comput tomographi show polypoid enhanc mural thicken involv distal bodi antro pylor region measur cm cm cm subtot gastrectomi done view clinic featur goo clinic suspicion malign gross examin show giant sessil hyperplast polyp lobul surfac microscopi reveal featur larg sessil hyperplast polyp without evid dysplasia patient symptomat reliev follow conclud giant ghps mimic gastric carcinoma endoscopi radiolog possibl giant ghp kept mind presenc intens contrast enhanc polypoid lesion gastric antrum long term endoscop follow recommend	D018256;D013274;D017219;D011127;D002277	T047;T191;T190
36,308,205	intranas glioma nasal heterotopia rare caus nasal polyp neonat month old boy present intranas polypoid mass protrud nostril present sinc birth grow slowli mass non pulsatil soft firm consist increas size cough cri compress jugular vein magnet reson imag contrast enhanc comput tomographi ct reveal lobul well circumscrib soft tissu mass left nasal caviti intracrani communic complet surgic excis mass carri via intranas endoscop approach histopatholog examin confirm diagnosi intranas glioma	D009298;D002828;D005910;D009669	T047;T046;T191
36,308,204	diagnost accuraci saliva specimen detect sar cov rt pcr covid caus sever acut respiratori syndrom coronavirus sar cov emerg pandem rapid spread million confirm case million death far nasopharyng swab nps vtm use gold standard respiratori specimen sar cov revers transcriptas real time pcr rrt pcr test virus also detect clinic specimen like bronchoalveolar lavag sputum saliva throat swab blood stool specimen	D000086402;D000086382	T005;T067;T047
36,308,203	covid time clinic classif covid pandem caus sar cov virus around year caus signific health care catastroph part world understand covid continu expand multipl newer develop presenc asymptomat case feco oral transmiss endotheli dysfunct exist classif develop current understand avail recent literatur evid attempt classif encompass pathogenesi clinic featur better understand diseas process pathogenesi covid continu evolv spike protein sar cov virus bind ace receptor caus direct cytopath damag hyperinflammatori injuri addit alveolar cell ace also distribut gastrointestin tract vascular endothelium ace sar cov interact engulf receptor lead deplet accumul ang via receptor atr bind caus upregul macrophag activ lead pro inflammatori cytokin releas interleukin il attribut caus hyperinflammatori syndrom covid addit also caus sever widespread endotheli injuri solubl il receptor thrombot complic occur follow cleavag activ von willebrand factor base understand clinic featur organ involv risk stratif diseas sever classifi covid patient asymptomat pulmonari gi system covid covid studi show infect prognosi differ distinct amongst group system covid patient like critic ill multi organ dysfunct thrombo embol complic	D000086382	T047;T067
36,308,202	three shade black secondari thrombot microangiopathi thrombot microangiopathi group disord character microangiopath hemolyt anemia thrombocytopenia organ damag wide age distribut heterogen present demand deeper understand pathogenesi tma primari tma distinct tma associ secondari caus remain clinic occult till precipit factor aggrav extent sever renal damag caus also distinct first alert signal could presenc schistiocyt peripher smear arteriolar thrombi light microscopi thus secondari tma identif under disord indispens target manag	D057049;D011697;D000743;D013927	T047;T046
36,308,201	acquir reactiv perfor collagenosi rare entiti uncommon site acquir reactiv perfor collagenosi arpc rare disord character transepiderm elimin tee collagen fiber seen adult diabet genet predisposit famili aggreg trauma bite scratch implic diabet develop microvascular diseas lead intens pruritus caus repeat micro trauma lead necrosi connect tissu dermi caus tee isol papul plaqu nodul central keratot plug most seen extensor surfac limb trunk face may involv histopatholog show extrus abnorm collagen fiber epidermi multipl treatment modal show variabl respons year old diabet femal multipl itchi well defin erythemat papul plaqu central adher crust lower back sinc month histopatholog show cup shape epiderm depress fill plug alter collagen acanthot epidermi hyperkeratosi parakeratosi under epidermi thin fine slit vertic orient basophil collagen fiber extrud	D003095;D012871;D003920	T047
36,308,200	evalu immunocytochemistri destain giemsa stain smear altern convent techniqu protocol immunocytochem icc stain may grnwald giemsa mgg stain smear difficult establish need hour abl use prestain slide icc specif case deliv time diagnos reduc inconveni patient	D004396	T197;T130;T109
36,308,199	telepatholog base screen tool covid leverag morpholog chang relat leukocyt peripher blood smear approach aftermath global pandem caus sever acut respiratori syndrom corona virus sar cov import quick develop rapid screen test becom clear point view contain also save live present explor studi develop telepatholog base screen tool use peripher blood smear pbs identifi coronavirus diseas covid posit case group patient flu like symptom consist posit negat sampl stain blood smear slide imag use autom slide scanner ai imag upload cloud analyz pathologist generat semi quantit leukocyt morpholog relat data telepatholog data compar data generat manual microscopi set smear slide also pathologist besid good correl data telepatholog manual microscopi abl achiev sensit specif respect identifi posit negat covid case use six paramet combin associ leukocyt morpholog morpholog featur includ plasmacytoid cell neutrophil dysplast promyelocyt neutrophil blast like cell apoptot cell smudg neutrophil neutrophil immatur granulocyt ratio although polymeras chain reaction pcr antibodi test superior perform pbs base telepatholog tool present potenti interim screen tool resourc limit set underdevelop develop countri	D019113;D000086382	T058;T067;T047
36,308,198	evalu util immunohistochemistri marker tool object diagnosi low grade myelodysplast syndrom routin report prospect observ studi diagnosi myelodysplast syndrom mds primarili reli detect morpholog dysplasia bone marrow subject mani studi report lack interobserv agreement report biopsi prefer specimen megakaryocyt assess studi bone marrow biopsi suspect mds patient persist undiagnos cytopenia util immunohistochemistri ihc cd p detect low grade mds analyz routin morpholog	D016159;D009190	T123;T046;T191;T116
36,308,197	feasibl indirect immunofluoresc iif alon screen method antinuclear antibodi connect diseas india sub himalayan region manag connect tissu disord ctds antinuclear antibodi ana test essenti diagnost prognost point view usual pattern obtain ana iif test correl specif autoantibodi obtain test ena liaelisa etc appli data western studi may need valid local popul like subject sub himalayan garhwal region area ctds common also suppos ana ifa pattern correl reliabl known popul minim cost manag ctds limit ena test time costlier ana iif henc studi undertaken know specif autoantibodi target ena lia ana iif pattern local popul	D000974;D003240	T129;T047;T116
36,308,196	basal cell carcinoma clinico patholog studi eastern india correl differ risk factor studi histolog variant mimick basal cell carcinoma bcc alongwith differ risk factor among group patient eastern india	D001151;D012878;D002280	T121;T196;T191;T131
36,308,195	anaplasia childhood rhabdomyosarcoma report entiti rhabdomyosarcoma rms common soft tissu sarcoma children anaplasia rare phenomenon seen childhood rms common histolog subtyp embryon follow alveolar spindl subtyp	D012208;D012509;D012983;D018232	T191
36,308,194	histomorpholog evalu placenta sar cov patient cross section studi sar cov emerg major pandem centuri littl known impact matern infect placent histopatholog histopatholog examin placent tissu contribut signific inform regard pathophysiolog diseas affect fetal outcom	D000086382;D047928;D011251;D010922	T047;T046;T067
36,308,193	signific cd express endometri carcinoma cd membran protein belong immunoglobulin superfamili regul macrophag phagocytosi negat cd express cancer cell membran would inhibit phagocyt activ immun cell connect unfavor prognosi leukemia malign various solid organ materi	D016889	T191
36,308,192	tumor bud valuabl prognost paramet endometri carcinoma tumor bud tb morpholog find believ play import role determin prognosi mani cancer	D016889	T191
36,308,191	endometri blood vessel morphometri patient present abnorm uterin bleed abnorm uterin bleed aub one common problem encount gynecolog practic various benign malign disord endometri tissu show vascular chang congest dilat vessel wall irregular	D004714;D016889	T047;T191

36,308,382

snp rs ros dcbld locus signific associ lung cancer risk poor surviv indian popul receptor tyrosin kinas rtk relev therapeut target treatment lung cancer germlin suscept variant influenc rtks may provid new insight regul rs locat genom interv two rtk gene rosdcbld ros alter implic lung carcinogenesi treatment respons latter remain poor understood

D008175;D014029

T191;T048

36,308,381

identif malign pap smear sampl use cgb nop gene methyl marker although various improv made report papanicolaou pap test recent year remain sever challeng yet address term determin standard methodolog categor atyp squamous cell undetermin signific asc us

D065309;D018290;D002583;D030361

T033;T047;T191;T025

36,308,380

anti prolif effect potenti lsdcorest inhibitor base molecular dynam model treatment sh syy neuroblastoma cancer cell line lysin specif demethylas demethylas enzym remov methyl group histon hkme hkme express mani cancer imped differenti contribut cancer cell prolifer cell metastasi invas associ inferior prognosi lsd associ corepressor protein corest util tetrahydrofol cofactor accept ch demethyl process fact cofactor best bound activ site inspir us explor interact lsdcorest enzym complex util molecular dynam simul aid design novel potent inhibitor

D056004;D009447

T066;T191;T044

36,308,379

role efna snp rs tumorigenesi metastasi colorect cancer bioinformat analysi hrm snp genotyp verif colorect cancer preval diseas poor prognosi known heterogen diseas mani differ clinic symptom molecular profil present studi aim systemat evalu associ snps mirna bind site target gene involv crc angiogenesi epitheli mesenchym transit cytoskeleton organ tumorigenesi metastasi crc

D015179;D020641

T191;T086

36,308,378

relaps childhood acut lymphoblast leukemia experi singl tertiari center thailand outcom relaps childhood acut lymphoblast leukemia develop countri improv time result risk adapt minim residu diseas direct therapi hematopoiet stem cell transplant immunotherapi studi examin surviv relaps childhood resourc limit countri therefor studi aim assess prognost factor surviv outcom relaps childhood major tertiari center southern thailand

D054198;D018380

T061;T191

36,308,377

cancer stem cell prognost biomark therapeut target use curcumin piperin extract multipl myeloma multipl myeloma mm hematolog bone marrow malign treat usual fatal medic resist major caus relaps due cancer stem cell cscs result studi aim identifi multipl myeloma cancer stem cell mmcscs bone marrow twelv mm patient patholog complet respons pcr chemotherapi investig potenti effect curcuminpiperin cp extract anti mmcscs treatment twenti newli diagnos patient

D009101;D003474

T121;T191;T130;T109

36,308,376

correl among kras mutat microsatellit instabl f fdg uptak colon cancer studi aim evalu correl maximum standard uptak valu suvmax kirsten ras sarcoma viral oncogen kras mutat microsatellit instabl msi status colon cancer

D019788;D003110

T191;T130;T109

36,308,375

import skin health promot children care makeup use skin cancer prevent numer pathogen complic affect skin prevent skin cancer microbi diseas dermal irrit anaphylaxi context correct use skin product includ sunscreen child makeup import promot skin health prevent advers health condit

D007722;D012878

T053;T191

36,308,374

investig role glutathion transferas gene histopatholog molecular subtyp gene gene interact suscept breast carcinoma ethnic north indian popul breast cancer bc genet clinic heterogen diseas includ complex interact gene gene gene environ compon studi aim explor whether glutathion transferas gsts gene polymorph role bc suscept evalu frequenc four subtyp bc base molecular classif follow microscop histolog analysi studi grade invas ductal carcinoma idc

D001943;D020022

T032;T191

36,308,373

constip sever qualiti life among patient cancer receiv prophylact laxat quasi experiment studi prophylact laxat associ decreas incid opioid induc constip among patient cancer studi aim evalu effect earli prophylact laxat therapi sever constip qualiti life among patient cancer receiv opioid

D000079689;D009369

T184;T047;T191

36,308,372

metabolit profil biolog activ assess casuarina equisetifolia bark incorpor gold nanoparticl casuarina equisetifolia bark rich various activ metabolit select studi due limit synthet antioxid advers side effect present studi aim enhanc effici effect extract incorpor gold nanoparticl au nps

D006046;D053768

T121;T196;T073

36,308,371

tnf allel carrier induc develop chronic lymphocyt leukemia sudanes popul earlier age sever studi perform investig associ tnf g asnp cll suscept howev result inconsist studi aim investig associ tnf g asnp tnf gene cll risk sudanes popul correl genotyp clinicopatholog featur

D014409;D015451

T129;T191;T116

36,308,370

line alu methyl hrhpv associ precancer cervic sampl studi conduct determin global dna methyl pattern cervic cell cytolog identifi atyp squamous cell unknown signific ascus normal lsil hsil histopatholog result

D065309;D011230;D002583;D030361

T033;T047;T191;T025

36,308,369

effect antimicrobi peptid fox lncrna ptcsc gene express colorect cancer crc normal cell innat immun system compon antimicrobi peptid amp exert various effect anticanc properti studi aim evalu amp anticanc effect colorect cancer crc cell express fox lncrna ptcsc gene

D062085;D015179

T123;T191;T114

36,308,368

cigarett display regul point sale pos impact cigarett sale studi aim determin impact cigarett display set cigarett sale store semarang citymethod research conduct august octob use quasi experiment studi approach conduct set cigarett display method cigarett display open day store cigarett display cover cloth pre post intervent period day respect five store cigarett display hidden pre post intervent period day respect three store cigarett sale record base mani pack stick sold per day visit store made everi two three day without prior notif store owner ensur cigarett display appropri record data sale data descript evalu use pair test confid level result result show one hidden cigarett display store r experienc signific decreas sale three hiddencov display store less signific decreas cigarett sale four hiddencov display store nt declin cigarett sale averag declin cigarett consumpt store packsday analysi sale per day pair pre post intervent test store cover display show differ pre post intervent sale store hidden display show differ conclus thus cover display affect store cigarett sale store hidden display show differ sale

D062789

T131;T073;T109

36,308,367

triplet folfoxiri versus doublet folfox folfiri regimen first line treatment metastat colorect carcinoma prospect phase ii random control trial outcom treatment metastat colorect cancer mcrc still unsatisfactori sever trial approv upfront treatment triplet regimen includ fluorouracil leucovorin irinotecan oxaliplatin improv outcom patient metastat diseas compar standard doublet regimen object studi evalu impact upfront treatment triplet folfoxiri regimen oncolog outcom respons rate surviv patient toler comparison standard doublet regimen

D015179

T191

36,308,366

full complianc adjuv endocrin therapi associ higher diseas free surviv hormon receptor posit negat chines breast cancer patient first tumor recurr character complianc status adjuv endocrin therapi aet relationship diseas free surviv dfs hormon receptor posit hr negat chines breast cancer bc patient first tumor recurr

D001943

T191

36,308,365

pki dual stain posit human papillomavirus dna test predict diagnosi abnorm cervic lesion northeastern thai women cervic cancer screen effect reduc new cervic cancer case includ thailand abnorm result subsequ refer colposcopi avoid unnecessari colposcopi effici triag still need valid studi aim investig overal posit cytolog base screen hpv detect pki dual stain evalu differ triag strategi predict diagnosi abnorm cervic lesion northeastern thailand

D018290;D002583;D030361;D065309;D000081483;D052685

T025;T191;T033;T005;T047

36,308,364

associ prestor smartphon monitor physic activ risk hpv infect cervic cancer studi determin preval hpv non vaccin women east china associ prestor smartphon monitor physic activ risk human papillomavirus hpv infect cervic cancer

D030361;D002583

T047;T191

36,308,363

diffus weight mri non invas diagnost tool rectal cancer aggress correl ki express tumor tissu appar diffus coeffici adc suggest prognost marker rectal carcinoma rc howev report data inconsist present studi aim assess relat adc valu ki express index patholog paramet egyptian rc patient

D038524;D012004

T060;T191

36,308,362

low dose berberin suppress cholangiocarcinoma cell progress multi kinas inhibitor berberin bbr natur isoquinolin alkaloid possess divers pharmacolog properti anti cancer effect demonstr mani vitro vivo studi studi inhibitori effect molecular mechan low dose bbr emt induc cell migrat invas capabl cholangiocarcinoma cca cell line demonstr

D001650;D001599;D018281;D000970

T121;T191;T109

36,308,361

surviv analysi clinic outcom paclitaxel carboplatin versus carboplatin gemcitabin patient advanc stage non small cell lung cancer singl center cohort studi palliat chemotherapi use platinum base doublet chemotherapi recommend one standard treatment patient advanc stage non small cell lung cancer nsclc negat egfr mutat studi aim compar clinic outcom patient treat paclitaxel carboplatin pc treat carboplatin gemcitabin cg

D002289;D008175

T191

36,308,360

role mirna foxo express breast cancer evalu role foxo mrna mi rna p express level bc patient

D001943;D035683

T123;T191;T114

36,308,359

estim neural tissu mobil breast cancer survivor lymphedema lymphedema breast cancer survivor common condit progress may lead entrap neuropathi lymphedema accumul fluid due remov lymph node caus stretch nerv fibr within skin compress top nerv bundl lead nerv entrap increas neural mechanosensit function impair shoulder protect neural respons movement traction

D001943;D000073116;D008209

T201;T191;T047;T046;T101

36,308,358

immun relat cerna network prognosi cervic cancer immunotherapi gain attent includ one treatment strategi cancer patient howev molecular mechan immun relat gene affin cervic cancer progress remain unclear studi develop immun relat compet endogen rna cerna network assess tumour infiltr immun cell toward prognosi cervic cancer

D062085;D002583;D035683

T123;T191;T114

36,308,357

relat work abil return work among iranian cancer survivor cancer diseas known disrupt person abil inflict physic psycholog financi social complic person therebi challeng individu return work aim studi investig abil cancer patient work return work

D000073116;D009369

T201;T191;T101

36,308,356

associ pikca mutat blood tumor infiltr lymphocyt peruvian breast cancer patient evalu relationship circul tumor dna ctdna presenc tumor featur includ tumor infiltr lymphocyt til level peruvian breast cancer patient

D000074141;D009369

T191;T114

36,308,355

efficaci short hydrat intermedi high dose cisplatin base chemotherapi outpati shortci trial support data exist concern short hydrat prevent cisplatin induc nephrotox howev studi exist data remain limit compris most retrospect data therefor studi would like evalu efficaci short hydrat use prospect cohort studi

D000970;D064420

T121;T046;T037;T109

36,308,354

studi preoper neutrophillymphocyt nlr plateletlymphocyt ratio plr predict factor endometri cancer evalu predict factor serum inflammatori marker malign potenti endometrium

D009504;D016889

T191;T025

36,308,353

mesenchym stem cell treatment aggrav tumor growth regardless rout administr vivo studi clarifi effect mscs cancer growth detect whether rout administr either local insid tumor tissu system could affect outcom treatment

D062085;D059630;D045164

T061;T123;T025;T114

36,308,352

risk factor diagnosi lung cancer poland larg scale popul base case control studi lung cancer one common dead malign neoplasm current one main caus cancer death worldwid studi aim identifi evalu patient characterist demograph lifestyl factor associ lung cancer diagnosi

D008175;D029424;D014376

T047;T191

36,308,351

comparison classif success rate differ machin learn algorithm diagnosi breast cancer identifi machin learn ml algorithm success predict diagnos breast cancer accord accuraci rate

D001943

T191

36,308,350

effect replac wharton acellular jelli fbs express megakaryocyt linear marker hematopoiet stem cell cd anim environ growth stem cell caus transmiss diseas immun problem recipi accord replac environ healthi environ least human resourc essenti one media use altern anim serum wharton acellular jelli awj therefor studi intend replac fbs wharton jelli investig effect express megakaryocyt relat gene marker stem cell

D008533;D059631

T018;T025

36,308,349

estim cancer treatment cost common type cancer separ pocket government cost afghanistan object studi estim cost cancer treatment servic common type cancer breast esophag colorect stomach lung public sector patient studi cross section studi conduct use medic record patient regist jamhuriyat hospit preval base approach use estim cost five major cancer type data patient elig includ analysi consid cost servic obtain averag cost privat hospit kabul also cost convert us dollar use exchang rate usd equal afn data analyz use ms excel program total number patient type cancer femal age group year illiter common cancer base cancer treatment servic cost health servic breast cancer follow esophagus colorect stomach lung moreov common cancer base cancer treatment servic cost health servic cancer patient need breast cancer follow esophagus colorect stomach lung moreov total cost cancer treatment us patient paid usd pocket cost cancer treatment servic common type cancer high consider portion paid patient need govern pay attent provis servic increas center provid servic exist facil also support intern communiti process enabl peopl access servic reduc econom burden patient

D001943;D015179

T191

36,308,348

measur occup fatigu among higher middl manag special cancer center covid pandem studi aim measur occup fatigu level describ sourc consequ occup fatigu among middl higher manag intern special cancer center covid pandem

D000086382;D009369

T047;T191;T067

36,308,347

valid immun status questionnair isq indonesian bahasa languag simpl assess perceiv immun status studi aim determin whether isq use assess immun status daili clinic practic indonesia translat questionnair bahasa analyz valid reliabl

D007802

T171

36,308,346

evalu cytochrom pe mrna express effect antioxid defens cell toxic print worker cytochrom pe cype metabol environment toxin howev compound metabol produc oxid stress caus cell toxic sometim transform

D016273;D000073888

T123;T037;T114

36,308,345

assess cell cycl induct apoptosi shiga like toxin produc escherichia coli h td breast cancer cell use flow cytometri low general toxic tumor express globotriaosylceramid gb shiga like toxin produc e coli propos anti cancer therapi specif target studi aim determin potenc local strain e coli h isol human cattl new breast cancer therapi analyz cell cycl inhibit apoptosi induct

D019453;D001943;D004927

T047;T007;T191

36,308,344

associ handgrip strength qualiti life breast cancer survivor systemat review meta analysi handgrip strength hgs indic general muscular strength cancer patient act relev marker associ mortal health studi aim evalu associ peripher muscl function health relat qualiti life hrqol breast cancer bc survivor

D000073116;D001943

T201;T191;T101

36,308,280

predictor sirolimus pharmacokinet variabl identifi use nonlinear mix effect approach systemat review sever sirolimus srl popul pharmacokinet poppk conduct explain pharmacokinet variabl result vari across studi thus conduct systemat review summar signific predictor influenc srl pharmacokinet variabl moreov discrep model methodolog across studi also review discuss four databas pubm cinahl complet scienc direct scopus systemat search pico framework use identifi elig studi conduct human employ nonlinear mix effect strategi base inclus exclus criteria studi includ srl pharmacokinet explain use compart model one studi assess model use extern approach rest employ basic advanc intern approach signific covari influenc srl pharmacokinet bodyweight age cypa polymorph gender bsa height cyclosporin dose trough concentr triglycerid total cholesterol hematocrit albumin aspart aminotransferas alanin aminotransferas total bilirubin bodyweight age cypa polymorph three identifi signific predictor srl clearanc review summar signific predictor predict srl clearanc subsequ use individu srl mainten dose howev poppk model select predict base resembl popul characterist target popul use conduct model moreov predict model target popul assess implement clinic practic

D020123;D016030

T061;T121;T195;T109

36,308,265

strive excel subspecialti medic train nigeria th theophilus oladapo ogunlesi lectur solid foundat laid prof theophilus oladapo ogunlesi found father nation postgradu medic colleg nigeria npmcn consist achiev mandat produc specialist medic practition nigeria ever chang world requir nigeria critic mass subspecialist tackl various old emerg ailment afflict citizenri subspecialist train popular among nigerian specialist yet subspecialist crave train nigerian born sub specialist diaspora will assist train left polici maker captain train institut seiz chanc move us forward view improv current embarrass low number subspecialist nigeria npmcn herebi beckon take lead combin excel relev

D007396

T065;T097

36,308,264

hoars nigerian tertiari health facil preval aetiolog predispos factor determin preval aetiolog predispos factor patient present hoars usmanu danfodiyo univers teach hospit sokoto

D006685;D005764

T184;T047

36,308,263

vascular injuri aetiolog present manag outcom tertiari hospit lago nigeria vascular injuri lead haemorrhag shock distal limb ischaemia especi arteri injuri life threaten state mandat urgent evalu intervent save life limb treatment aim restor blood flow replac lost blood within golden hour stabilis cardiovascular haemodynam avert irrevers ischaem damag aim studi analys clinic profil vascular injuri manag outcom institut

D057772

T037

36,308,262

predictor caus hospit matern death within h admiss tertiari hospit south western nigeria retrospect cohort studi effici comprehens emerg obstetr care cemoc consider reduc burden matern mortal mm nigeria inform risk matern death within h admiss reflect qualiti cemoc offer

D063130;D014597;D046110;D018805

T047;T040;T046

36,308,261

socio demograph factor influenc measur cognit function earli adolesc student abuja nigeria brain earli adolesc period undergo enhanc chang radic reorganis neuron network lead improv cognit capac complex interplay exist environ genet influenc outcom intellectu capabl therefor aim evalu relationship socio demograph variabl measur cognit function intellig quotient iq academ perform earli adolesc

D007360;D013334

T081;T098;T041

36,308,260

evalu effect nutrit versus non nutrit pacifi adjunct local anaesthesia male neonat circumcis use plastibel techniqu prospect randomis control studi male circumcis common surgic procedur worldwid often carri religi cultur medic public health reason common perform neonat period mani studi shown pain common intra post oper complic ensur proper analgesia procedur mani surgeon opt use pacifi adjunct anaesthesia neonat circumcis aim studi compar nutrit pacifi nps versus non nps nnps adjunct local anaesthesia male neonat circumcis use plastibel techniqu

D002944

T061

36,308,259

non covid uptak person protect equip rule complianc amongst industri worker kano nigeria everi workplac got hazard mani differ form rang sharp fall object chemic infect nois lot potenti danger situat occup safeti health administr mandat employ protect employe potenti danger workplac hazard person protect equip ppe play import role prevent ensur health safeti amongst industri worker studi aim determin use ppe rule complianc amongst industri worker kano state

D016272;D000067393

T078;T091;T073

36,308,258

willing pay covid vaccin oneself one child among individu attend tertiari care centr west bengal india free cost suppli could meet demand coronavirus diseas covid vaccin india govern approv inject option price aim determin much money individu would will pay covid vaccin children assess factor determin

D000086663;D000086382

T200;T047;T067

36,308,257

accept appropri feasibl webinar strengthen research capac covid era nigeria challeng pose covid pandem necessit increas use onlin virtual train platform object studi assess accept appropri feasibl virtual space strengthen research capac nigeria

D000086382

T047;T067

36,308,256

nigeria nation health insur author act implic toward achiev univers health coverag nation health insur scheme nhis face sever inher system drawback toward achiev univers health coverag nigerian led sign new nation health insur author act nhia articl highlight benefit nhia discuss possibl challeng way forward implement narrat review past literatur search pubm medlin african journal onlin goggl conduct total public initi retriev follow data triangul final use author also includ experi nhia address shortcom previous nhis howev would still face sever challeng implement low govern fund prioriti health shortag healthcar worker poor healthcar coverag well problem enforc mandat nigerian enrol impend constraint must surmount stakehold must involv ensur act accomplish aim

D019472;D009313

T078;T058;T170

36,308,255

recurr tumor ameloblastoma clinicopatholog featur diagnost outcom ameloblastoma benign epitheli odontogen tumor tendenc recurr recurr tumor could behav unpredict atyp microscop chang

D000564;D009808

T191

36,308,253

soft tissu sarcoma arm oncosurg reconstruct challeng case report soft tissu sarcoma sts rare tumor may occur upper extrem present delay slow growth lack symptom lesion discov via physic radiolog examin definit diagnosi conduct histopatholog present case year old man swell dorsum arm nocturn hyperhidrosi weight loss radiolog examin reveal possibl malign metabol activ left axillari lymph node tumor excis defect cover use pedicl myocutan latissimus dorsi flap distal portion muscl attach remnant tricep brachii tendon postop histopatholog reveal high malign sts patient remain relaps free regimen adjuv chemotherapi satisfactori aesthet result modest elbow extens evid month follow proper manag upper extrem sts crucial prevent recurr metastasi

D017695;D019651;D012509

T061;T191;T037

36,308,252

cumul inflammatori burden caus multipl complic success pelvic surgeri advanc ovarian cancer vesicovagin rectovagin fistula may develop pelvic metastasi ovarian carcinoma purul discharg vagina result frequent vagin urinari tract infect trigger chronic inflamm incapacit symptom creat serious medic psychosoci problem result low self esteem qol studi present metastat ovarian cancer case admit bilater nephrostomi nonfunct colostomi high volum recto vesicovagin fistula debulk frequent urinari tract infect system inflammatori respons syndrom surgeri perform success howev deal complic electrolyt imbal wound infect continu sir cumul inflammatori burden caus advanc carcinoma complic creat serious medic psychosoci problem manag patienc

D014719;D002277;D010051

T191;T190

36,308,251

endobronchi actinomycosi case report extrem rare diseas slow cours actinomycosi high mortal risk proper treat pulmonari actinomycosi clinic radiolog analog tuberculosi foreign bodi aspir lung abscess lung cancer therefor often caus misdiagnosi delay diagnosi year old male patient follow diagnosi chronic obstruct pulmonari diseas copd lung adenocarcinoma admit outpati clinic complaint chronic cough chest ct cavitari lesion upper lobe right lung observ sputum acid fast bacilli afb negat consecut time fungal direct examin negat growth mycobacterium cultur fungal cultur flexibl bronchoscopi reveal rais hard white color lesion mucosa obliter apic anterior segment bronchial entranc right lung upper lobe diagnosi actinomycosi made sulfur granul seen patholog result biopsi lavag detect sulfur granul biopsi essenti diagnosi actinomycosi near complet respons usual obtain long term antibiot treatment altern method surgic debrid consid case respond antibiot treatment

D000196;D008171

T047

36,308,250

effect differ polymer time color chang transluc paramet surfac hard bulk fill resin composit polymer play import role optic mechan properti resin composit materi

D003188;D003764

T122

36,308,249

relationship crpalbumin ratio level prognosi pregnant covid patient c reactiv protein crp albumin ratio car one new tool assess sever inflamm use determin clinic sever prognosi mani diseas

D002097;D000086382

T129;T047;T116;T067

36,308,248

profil insulin resist pregnant women late third trimest nigeria descript cross section report exagger level insulin resist ir associ poor pregnanc outcom identifi affect women may forestal outcom report ir predictor among pregnant women nigeria

D007333;D006943;D006973;D016640

T033;T047;T046

36,308,247

subclin hypothyroid children idiopath childhood nephrot syndrom tertiari institut south west nigeria hypothyroid children nephrot syndrom ns often attribut prolong loss thyroxin bind globulin thyroid hormon alongsid protein urin histor associ steroid resist ns alon howev recent evid support fact subclin hypothyroid sch occur even children steroid respons ns complic weight gain hypercholesterolemia delay growth delay puberti depress could result hypothyroid erron attribut ns effect steroid use treatment incident salt intak major form dietari iodin often restrict children ns possibl exacerb under hypothyroid state

D009404;D007037;D007455

T123;T047;T121;T196

36,308,246

allerg rhiniti indic otiti media effus children seen aminu kano teach hospit kano allerg rhiniti ar multifoc ige mediat type hypersensit reaction involv nasal mucosa character excess sneez wateri rhinorrhea nasal itch nasal stuffi eye itch tympanometri simpl rapid object test easili carri use tympanometri clinic set improv detect middl ear effus middl ear abnorm ar found one predispos factor develop otiti media effus ome children

D010034;D010033;D065631;D004427

T047

36,308,245

tissu doppler echocardiograph evalu cardiac function children mucopolysaccharidosi type iii diseas mucopolysaccharidosi type iii mps iii extrem rare group diseas among mps type recent year studi presenc import cardiac involv mps iii patient type mps

D015150;D009083

T060;T047

36,308,244

perfus ndex pleth variabl index titl earli ndicat brachial plexus block studi evalu perfus index pi pleth variabl index pvi success pi pvi block patient undergo brachial plexus limit quit inadequ

D065527;D001917

T061;T023

36,308,243

measur differ diaper paramet evalu postcircumcis bleed signific nfant health evalu circumcis bleed depend visual chang diaper diaper differ product featur absorb capac appar chang diaper may vari accord absorb capac may parallel amount bleed signific visual differ occur patient hemodynam may impair

D003963

T047

36,308,242

assess skelet relationship cleft palat without cleft lip cone beam comput tomographi studi pakistani popul understand differ skelet relationship orofaci cleft use cone beam comput tomographi cbct may eventu lead develop better diagnosi treatment protocol facial deform

D002971;D002972

T019

36,308,241

clinic radiolog outcom lock plate osteosynthesi distal metadiaphys tibial fractur accord sever comminut varus reduct would prefer lower clinic outcom optim treatment distal tibial fractur remain matter debat nonetheless plate osteosynthesi produc favor result intramedullari stabil aspect align restor

D013978;D018460

T037

36,308,240

chang surfac characterist permeabl human enamel subject radiat therapi radiat relat cari complex destruct lesion lead uncompromis damag enamel dentin patient suffer head neck cancer manag radiotherapi

D014070

T023

36,308,239

anti microbi efficaci root canal prepar decidu teeth manual rotari file random clinic trial pulpectomi erad microb primari root canal accomplish biomechan prepar could carri either manual rotari instrument

D018915;D014094

T061;T023

36,308,238

possibl predict outcom endovascular thrombectomi hyperdens middl cerebr arteri sign time first admiss hyperdens middl cerebr arteri sign hmcas admiss non contrast comput tomographi ncct well character phenomenon acut ischem stroke

D020521;D000083242;D002545

T047;T046

36,308,237

new perspect relationship anchorag palat morpholog three dimension digit model analysi tooth movement general analyz two dimens cephalometr radiograph nowaday digit model analysi harm effect patient use evalu palat morpholog coron tooth movement comfort easi way

D008437;D008312

T023;T190

36,308,236

abo rh blood type clinic consequ covid infect suffici evid show relationship blood type sever sever acut respiratori syndrom coronavirus sar cov infect studi plan investig effect abo blood group clinic outcom sar cov infect

D000086382

T047;T067

36,308,235

clinic awar knowledg breast cancer relat lymphedema among group psychiatrist turkey onlin survey point view role physiatrist import clinic care breast cancer relat lymphedema bcrl patient set manag rehabilit strategi

D001943;D008209;D011570

T091;T191;T097;T047;T046

36,308,234

impact covid pandem academ train psychosoci well undergradu dental student nigeria educ institut nigeria shut long onset covid pandem prevent measur affect dental student academ clinic train

D000086382

T047;T067

36,308,233

serum folat level children epilepsi seen tertiari health care facil north central nigeria children suffer epilepsi maintain antiepilept drug a ensur reason qualiti life drug howev without side effect notabl among interfer metabol folat attend clinic implic megaloblast anemia bleed diathesi

D014635;D004827

T033;T121;T047;T109

36,308,232

thoracoscop repair congenit diaphragmat hernia neonat tip trick learn institut experi congenit diaphragmat hernia cdh anomali signific morbid neonat tradit manag open approach recent trend toward minim invas approach

D065630

T019

36,308,231

effect differ posit unerupt lower third molar teeth fragil mandibular angl finit element analysi mandibular bone largest strongest bone comparison bone face skeleton howev common fractur facial injuri locat fractur mandibl depend various factor relationship impact lower third molar teeth mandibular angl fractur subject mani epidemiolog studi argu risk fractur mandibular angl two four time particular impact partial impact third molar teeth howev effect posit impact tooth mandibular angl fractur clear yet

D014095;D008337

T047;T037

36,308,230

outcom surgic manag symptomat renal angiomyolipoma ibadan nigeria sub saharan africa renal angiomyolipoma commonest benign solid kidney neoplasm though rare clinic practic advent radiolog imag techniqu refin surgic approach techniqu avail mammalian target rapamycin improv outcom cohort patient

D018207;D007680;D006222

T191

36,308,229

build respons healthcar system nigerian experi healthcar system must respons need client entail element digniti confidenti autonomi prompt attent social support basic amen choic provid target toward improv mainten qualiti healthcar consequ improv patient outcom reduc cost

D003695;D012944

T054;T058;T093

36,308,226

dr p v gharpur emin indian pathologist pioneer start oral polio vaccin india dr purushottam vishwanath gharpur emin indian pathologist emeritus professor patholog grant medic colleg bombay pioneer carri first field trial polio vaccin mark begin polio erad program india dr gharpur set exampl take laboratori work field prove laboratori research use better societi mesmer stori dr gharpur life describ paper

D000072142;D011051

T047;T097

36,308,213

primari leiomyosarcoma ovari rare malign incident find primari leiomyosarcoma plms ovari extrem rare tumor compris ovarian tumor ovarian malign primari ovarian sarcoma case report till date year old postmenopaus femal present abdomin pain last month ultrasonographi mri reveal heterogen enhanc solid lobul mass left adnexa abut fundus uterus bowel loop endometri caviti normal ovarian marker ca cea ca hematolog paramet within normal limit ldh near normal iuml specimen sent frozen section diagnosi malign spindl cell lesion ovari render histopatholog ovarian mass reveal intersect fascicl tumor cell consist ovoid spindl shape cell moder amount cytoplasm bizarr atyp cell seen singl dispers small aggreg along brisk mitot activ focal area necrosi hemorrhag also note immunohistochemistri show strong posit smooth muscl actin caldesmon focal posit desmin epitheli membran antigen ema note lesion negat inhibin calretinin cd final diagnosi primari ovarian leiomyosarcoma given base histopatholog immunohistochemistri plms ovari rare incident find postmenopaus women high malign tumor carri poor prognosi henc earli diagnosi surgic treatment cytoreduct improv patient surviv

D007890;D010051

T191

36,308,212

renal hepat chang case envenom snake bite case report review literatur snake bite major health hazard moreov tropic countri densiti snake frequent human contact lack diagnost treatment facil add high morbid mortal organ escap effect envenom heart liver kidney cns local bite site effect snake venom kidney document literatur avail patholog effect envenom human liver lack present case elder male renal hepat manifest envenom

D012909

T037

36,308,211

differenti pediatr cystic nephroma common renal multicyst lesion case report pediatr cystic nephroma rare clinic benign renal tumor pediatr renal cystic lesion complex imag find tumor appear often nonspecif care patholog examin necessari discuss diagnosi pediatr cystic nephroma differenti multicyst dysplast kidney cystic partial differenti nephroblastoma

D007680;D009396;D052177;D021782;D009447

T019;T047;T191

36,308,210

acut pancreat masquerad mesentr growth covid patient case report covid infecti diseas caus sever acut respiratori syndrom coronavirus sar cov common affect respiratori system produc pneumonia like symptom among extrapulmonari manifest involv gastrointestin tract common symptom nausea vomit diarrhea abdomin pain coronavirus act target ace receptor alveoli lung receptor also present organ pancrea affect pancrea well thus caus acut pancreat discuss case year old hypertens male covid present atyp present acut abdomin pain episod vomit laboratori investig inconclus imag find suggest small bowel obstruct perfor thus exploratori laparotomi done mesenter growth found report acut pancreat histopatholog therefor attent paid pancreat involv atyp present covid patient

D000086382;D010195

T047;T046;T067

36,308,209

primari hepat lymphoma diagnost dilemma primari non hodgkin lymphoma liver rare malign report case year old femal present dull ach right hypochondrium decreas appetit sinc month ct scan abdomen pelvi show enlarg liver ill defin soft tissu lesion aris left lobe measur cm suggest primari hepat neoplasm ct scan chest abdomen pelvi whole bodi positron emiss tomographi show involv bone marrow lymph node spleen organ liver function test alpha fetoprotein carcinoembryon antigen level normal serolog negat virus patholog examin favor diagnosi burkitt lymphoma cytogenet studi myc transloc suggest confirm diagnosi sinc ki index near characterist burkitt lymphoma

D002051;D008113

T191

36,308,208

angiomatoid fibrous histiocytoma report two case initi constru sarcoma unusu clinico patholog featur angiomatoid fibrous histiocytoma afh rare soft tissu tumor uncertain differenti low metastat potenti common occur children adolesc young adult involv extrem due rare natur divers present clinic morpholog often misdiagnos becom import correct diagnos lesion given distinct therapeut implic present clinic radiolog patholog find two rare case afh sinc afh rare soft tissu tumor low malign potenti pathologist clinician awar entiti encount soft tissu mass extrem child adolesc accord appropri treatment case

D018219;D051677;D012983

T191

36,308,207

high grade mix neuroendocrin non neuroendocrin neoplasm gastroesophag junction rare case report review literatur mix neuroendocrin non neuroendocrin neoplasm minen recent describ entiti esophagus latest fifth edit classif digest system tumor often difficult patholog diagnosi especi small preoper biopsi herein report case high grade minen gastroesophag junction diagnos squamous cell carcinoma preoper biopsi subsequ high grade minen esophagogastrectomi specimen compris area mucoepidermoid carcinoma larg cell neuroendocrin carcinoma nec report accentu import deeper multisit preoper biopsi manag complet differ minen esophag squamous cell carcinoma

D004938;D000077277;D018358;D018278

T191

36,308,206

giant hyperplast gastric polyp diagnost dilemma gastric hyperplast polyp ghp account major benign gastric polyp ghps cm asymptomat incident detect endoscopi radiolog increas size polyp manifest upper gastrointestin bleed iron defici anemia gastric outlet obstruct goo report unusu case giant ghp simul gastric carcinoma pose diagnost challeng surgeon emphas diagnost role histopatholog year old femal present clinic featur progress goo year endoscopi reveal eccentr prolif lesion antrum comput tomographi show polypoid enhanc mural thicken involv distal bodi antro pylor region measur cm cm cm subtot gastrectomi done view clinic featur goo clinic suspicion malign gross examin show giant sessil hyperplast polyp lobul surfac microscopi reveal featur larg sessil hyperplast polyp without evid dysplasia patient symptomat reliev follow conclud giant ghps mimic gastric carcinoma endoscopi radiolog possibl giant ghp kept mind presenc intens contrast enhanc polypoid lesion gastric antrum long term endoscop follow recommend

D018256;D013274;D017219;D011127;D002277

T047;T191;T190

36,308,205

intranas glioma nasal heterotopia rare caus nasal polyp neonat month old boy present intranas polypoid mass protrud nostril present sinc birth grow slowli mass non pulsatil soft firm consist increas size cough cri compress jugular vein magnet reson imag contrast enhanc comput tomographi ct reveal lobul well circumscrib soft tissu mass left nasal caviti intracrani communic complet surgic excis mass carri via intranas endoscop approach histopatholog examin confirm diagnosi intranas glioma

D009298;D002828;D005910;D009669

T047;T046;T191

36,308,204

diagnost accuraci saliva specimen detect sar cov rt pcr covid caus sever acut respiratori syndrom coronavirus sar cov emerg pandem rapid spread million confirm case million death far nasopharyng swab nps vtm use gold standard respiratori specimen sar cov revers transcriptas real time pcr rrt pcr test virus also detect clinic specimen like bronchoalveolar lavag sputum saliva throat swab blood stool specimen

D000086402;D000086382

T005;T067;T047

36,308,203

covid time clinic classif covid pandem caus sar cov virus around year caus signific health care catastroph part world understand covid continu expand multipl newer develop presenc asymptomat case feco oral transmiss endotheli dysfunct exist classif develop current understand avail recent literatur evid attempt classif encompass pathogenesi clinic featur better understand diseas process pathogenesi covid continu evolv spike protein sar cov virus bind ace receptor caus direct cytopath damag hyperinflammatori injuri addit alveolar cell ace also distribut gastrointestin tract vascular endothelium ace sar cov interact engulf receptor lead deplet accumul ang via receptor atr bind caus upregul macrophag activ lead pro inflammatori cytokin releas interleukin il attribut caus hyperinflammatori syndrom covid addit also caus sever widespread endotheli injuri solubl il receptor thrombot complic occur follow cleavag activ von willebrand factor base understand clinic featur organ involv risk stratif diseas sever classifi covid patient asymptomat pulmonari gi system covid covid studi show infect prognosi differ distinct amongst group system covid patient like critic ill multi organ dysfunct thrombo embol complic

D000086382

T047;T067

36,308,202

three shade black secondari thrombot microangiopathi thrombot microangiopathi group disord character microangiopath hemolyt anemia thrombocytopenia organ damag wide age distribut heterogen present demand deeper understand pathogenesi tma primari tma distinct tma associ secondari caus remain clinic occult till precipit factor aggrav extent sever renal damag caus also distinct first alert signal could presenc schistiocyt peripher smear arteriolar thrombi light microscopi thus secondari tma identif under disord indispens target manag

D057049;D011697;D000743;D013927

T047;T046

36,308,201

acquir reactiv perfor collagenosi rare entiti uncommon site acquir reactiv perfor collagenosi arpc rare disord character transepiderm elimin tee collagen fiber seen adult diabet genet predisposit famili aggreg trauma bite scratch implic diabet develop microvascular diseas lead intens pruritus caus repeat micro trauma lead necrosi connect tissu dermi caus tee isol papul plaqu nodul central keratot plug most seen extensor surfac limb trunk face may involv histopatholog show extrus abnorm collagen fiber epidermi multipl treatment modal show variabl respons year old diabet femal multipl itchi well defin erythemat papul plaqu central adher crust lower back sinc month histopatholog show cup shape epiderm depress fill plug alter collagen acanthot epidermi hyperkeratosi parakeratosi under epidermi thin fine slit vertic orient basophil collagen fiber extrud

D003095;D012871;D003920

T047

36,308,200

evalu immunocytochemistri destain giemsa stain smear altern convent techniqu protocol immunocytochem icc stain may grnwald giemsa mgg stain smear difficult establish need hour abl use prestain slide icc specif case deliv time diagnos reduc inconveni patient

D004396

T197;T130;T109

36,308,199

telepatholog base screen tool covid leverag morpholog chang relat leukocyt peripher blood smear approach aftermath global pandem caus sever acut respiratori syndrom corona virus sar cov import quick develop rapid screen test becom clear point view contain also save live present explor studi develop telepatholog base screen tool use peripher blood smear pbs identifi coronavirus diseas covid posit case group patient flu like symptom consist posit negat sampl stain blood smear slide imag use autom slide scanner ai imag upload cloud analyz pathologist generat semi quantit leukocyt morpholog relat data telepatholog data compar data generat manual microscopi set smear slide also pathologist besid good correl data telepatholog manual microscopi abl achiev sensit specif respect identifi posit negat covid case use six paramet combin associ leukocyt morpholog morpholog featur includ plasmacytoid cell neutrophil dysplast promyelocyt neutrophil blast like cell apoptot cell smudg neutrophil neutrophil immatur granulocyt ratio although polymeras chain reaction pcr antibodi test superior perform pbs base telepatholog tool present potenti interim screen tool resourc limit set underdevelop develop countri

D019113;D000086382

T058;T067;T047

36,308,198

evalu util immunohistochemistri marker tool object diagnosi low grade myelodysplast syndrom routin report prospect observ studi diagnosi myelodysplast syndrom mds primarili reli detect morpholog dysplasia bone marrow subject mani studi report lack interobserv agreement report biopsi prefer specimen megakaryocyt assess studi bone marrow biopsi suspect mds patient persist undiagnos cytopenia util immunohistochemistri ihc cd p detect low grade mds analyz routin morpholog

D016159;D009190

T123;T046;T191;T116

36,308,197

feasibl indirect immunofluoresc iif alon screen method antinuclear antibodi connect diseas india sub himalayan region manag connect tissu disord ctds antinuclear antibodi ana test essenti diagnost prognost point view usual pattern obtain ana iif test correl specif autoantibodi obtain test ena liaelisa etc appli data western studi may need valid local popul like subject sub himalayan garhwal region area ctds common also suppos ana ifa pattern correl reliabl known popul minim cost manag ctds limit ena test time costlier ana iif henc studi undertaken know specif autoantibodi target ena lia ana iif pattern local popul

D000974;D003240

T129;T047;T116

36,308,196

basal cell carcinoma clinico patholog studi eastern india correl differ risk factor studi histolog variant mimick basal cell carcinoma bcc alongwith differ risk factor among group patient eastern india

D001151;D012878;D002280

T121;T196;T191;T131

36,308,195

anaplasia childhood rhabdomyosarcoma report entiti rhabdomyosarcoma rms common soft tissu sarcoma children anaplasia rare phenomenon seen childhood rms common histolog subtyp embryon follow alveolar spindl subtyp

D012208;D012509;D012983;D018232

T191

36,308,194

histomorpholog evalu placenta sar cov patient cross section studi sar cov emerg major pandem centuri littl known impact matern infect placent histopatholog histopatholog examin placent tissu contribut signific inform regard pathophysiolog diseas affect fetal outcom

D000086382;D047928;D011251;D010922

T047;T046;T067

36,308,193

signific cd express endometri carcinoma cd membran protein belong immunoglobulin superfamili regul macrophag phagocytosi negat cd express cancer cell membran would inhibit phagocyt activ immun cell connect unfavor prognosi leukemia malign various solid organ materi

D016889

T191

36,308,192

tumor bud valuabl prognost paramet endometri carcinoma tumor bud tb morpholog find believ play import role determin prognosi mani cancer

D016889

T191

36,308,191

endometri blood vessel morphometri patient present abnorm uterin bleed abnorm uterin bleed aub one common problem encount gynecolog practic various benign malign disord endometri tissu show vascular chang congest dilat vessel wall irregular

D004714;D016889

T047;T191