PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,666,336 | prolactin reduc hippocamp parvalbumin gabaa receptor express femal mice parvalbumin pv posit cell strateg element neuron network capabl influenc memori learn process howev known whether pituitari hormon may relat pv express hippocampus part limbic system import function learn memori | D006624;D006966;D010320;D011388;D011963 | T116;T023;T047;T121;T123;T026;T125;T192 |
34,666,335 | featur pathobiolog clinic translat approv treatment coronavirus diseas sever acut respiratori syndrom coronavirus sar cov current import etiolog agent acut respiratori distress syndrom ard million infect death last year worldwid sever reason paramet respons difficult manag coronavirus diseas covid patient first virus behavior factor high transmiss rate differ molecular cellular mechan pathogenesi remain matter controversi anoth factor | D000086382 | T047;T067 |
34,666,334 | variabl clinic present children hereditari hypophosphatem ricket hypercalciuria case seri review literatur hereditari hypophosphatem ricket hypercalciuria hhrh rare condit renal phosphat wast due slca mutat j hum genet patient exhibit low serum phosphorus high dihydroxyvitamin inappropri high urin phosphat calcium howev symptom vari littl known specif phenotyp genotyp correl | D053098;D012279 | T047 |
34,666,333 | risk stratif predict factor cephalosporin allergi case control studi compar penicillin cephalosporin allergi less common children diagnost approach less standard recent european academi allergi clinic immunolog posit paper provid risk stratif system patient suspect lactam hypersensit reaction | D000900;D004342 | T195;T046;T121 |
34,666,331 | synergist inhibitori effect combin mk azd marimo cell harbor calreticulin gene mutat somat mutat calreticulin calr gene occur myeloprolif neoplasm mpn patient lack janus kinas thrombopoietin receptor mpl mutat molecular pathogenesi mpn mutat calr unclear limit treatment calr gene mutant patient | D037282;D009196 | T116;T191;T123 |
34,666,330 | applic artifici intellig earli gastric cancer diagnosi develop new technolog magnifi endoscopi narrow band imag endoscopist achiev better accuraci diagnosi gastric cancer gc various aspect howev master skill take substanti effort could difficult inexperienc doctor therefor novel diagnost method base artifici intellig ai develop effect confirm mani studi ai system use convolut neural network show marvel result ongo trial comput aid detect colorect polyp | D013274 | T191 |
34,666,328 | initi result mous brain pet insert stagger layer doi detector object small anim positron emiss tomographi pet requir submillimet resolut better quantif radiopharmaceut hand depth interact doi inform essenti preserv spatial resolut maintain sensit recent develop stagger layer doi detector mm crystal pitch mm total crystal thick demonstr imag perform doi detector full ring geometri studi present initi imag result obtain mous brain pet prototyp develop stagger layer doi detector approach prototyp mm inner diamet mm axial field view pet scanner consist doi detector stagger layer lyso crystal array mm coupl silicon photomultipli array physic perform evalu term nema nu protocol main result measur spatial resolut center mm radial offset mm mm filter back project respect peak absolut sensit obtain energi window kev resolut phantom imag result show clear identif submillimetr rod pattern order subset expect maxim algorithm inter crystal scatter reject use narrow energi window could enhanc resolv mm rod signific signific anim imag experi detail mous brain structur cortex thalamus clear identifi high contrast conclus success develop mous brain pet insert prototyp stagger layer doi detector | D049268;D019275 | T130;T121;T060 |
34,666,327 | dimension stationari cascad gamma ray coincid imag object certain radionuclid decay emit two gamma photon consecut within short time interv call cascad gamma ray locat radiopharmaceut molecul emit cascad gamma ray identifi coincid detect photon cascad photon detect collim mechan locat molecul infer intersect back project two photon approach work report design evalu three dimension stationari imag base concept imag distribut cascad emit radionuclid radiopharmaceut therapi imag compos two gamma ray camera assembl l shape camera nai tl scintil base one multi slit collim multi pinhol collim field view fov mm mm l base uniqu characterist cascad coincid event use direct back project algorithm reconstruct point sourc imag assess imag intrins spatial resolut standard maximum likelihood expect maxim algorithm reconstruct phantom imag main result evalu perform imag simul prototyp form radionuclid lu cascad photon emitt simul imag coincid detect effici center fov spatial resolut mm prototyp imag correspond valu mm respect simul hot rod experiment cardiac phantom studi demonstr first three dimension cascad gamma coincid imag fulli function | D015902;D019275 | T130;T074;T121 |
34,666,321 | ipem topic report result uk survey use onlin treatment monitor solut imrtvmat numer commerci technolog onlin treatment monitor otm radiotherapi rt current avail includ electron portal imag devic epid vivo dosimetri ivd transmiss detector log file analysi despit uk exist limit guidanc implement commiss system clinic use inform resourc requir set maintain servic radiotherapi special interest group work parti establish institut physic engin medicin form view reassess current practic otm uk aim develop consensus guidelin implement system survey distribut head medic physic uk rt depart investig avail otm uk estim workload clinic implement method analysi qualiti assur opinion futur direct survey achiev respons rate demonstr otm wide support uk respond indic patient undergo otm epid ivd eivd popular form otm activ eivd servic report respond believ optim solut demonstr steadi increas adopt sinc form otm use adopt minor centr financi barrier increas staff workload continu hinder wider implement centr devic autom integr key factor success futur adopt requir support treatment machin otm manufactur survey provid updat analysi use otm method across uk futur guidanc recommend commiss adopt local toler root caus analysi strategi assist depart intend implement otm | D050397 | T061 |
34,666,320 | carbon dot deriv beta vulgari evalu potenti antioxid anticanc agent carbon dot cds endow outstand physico chemic characterist expediti garner tremend popular scientif communiti cds synthes varieti natur resourc replac metal semiconductor quantum dot rang applic bio imag sens catalysi herein cds green synthes beta vulgari via singl step hydrotherm approach b cds synthes carbon dot character use uv visibl spectrophotometri fluoresc spectroscopi high resolut transmiss electron microscopi hr tem fourier transform infrar spectroscopi ft ir x ray diffract techniqu xrd raman spectroscopi b cds henc develop exhibit signatur excit depend fluoresc emiss intens emiss green region quantum yield b cds obtain synthet approach evinc appreci valu antioxid properti b cds evalu use diphenyl picrylhydrazyl dpph assay obtain maximum scaveng activ concentr g ml under mechan illustr blood compat b cds assess use haemolysi assay cytotox evalu use mtt assay show signific cell growth inhibit human breast cancer mcf hepatocellular carcinoma hepg cell line succinct studi demonstr inher therapeut potenti biocompat carbon dot | D000970;D000975;D045663 | T044;T121;T109;T123;T073;T039 |
34,666,318 | investig spatial fraction radiat induc bystand effect mathemat model approach radiat induc bystand effect ribe shown caus death cell receiv littl physic dose standard radiotherapi uniform field deliv cell direct expos radiat phenomenon neglect howev role ribe may becom influenti heterogen field consid mathemat model use determin heterogen field might influenc cell surviv establish techniqu account direct effect radiat gain full appreci non uniform field impact cell surviv also necessari consid indirect effect radiat work utilis mathemat model account direct effect radiat cell ribe model use investig spatial fraction radiotherapi plan impact cell surviv vitro predict compar surviv normal cancer cell follow exposur spatial fraction plan use clinic linac model also use explor spatial fraction radiotherapi impact tumour control vivo result suggest spatial fraction plan associ higher equival uniform dose convent uniform plan clinic relev dose model predict small chang chang normal tissu complic probabl compar larger protect seen clinic contradict central paradigm radiotherapi uniform field assum maximis cell kill may import futur radiotherapi optimis | D009369;D011832 | T191;T047;T037 |
34,666,315 | light weight electrophysiolog hardwar softwar platform cloud base neural record experi object neural activ repres function readout neuron increas import monitor wide rang experi extracellular record emerg power techniqu measur neural activ method lead destruct degrad cell measur current approach electrophysiolog low throughput experi due manual supervis expens equip bottleneck limit broader infer achiev numer long term record sampl approach develop piphi inexpens open sourc neurophysiolog record platform consist hardwar softwar easili access control via standard web interfac internet thing iot protocol main result use raspberri pi primari process devic along intan bioamplifi design hardwar expans circuit board softwar enabl voltag sampl user interact standalon system valid primari human neuron show reliabl collect neural activ near real time signific hardwar modul cloud softwar allow remot control neural record experi well horizont scalabl enabl long term observ develop organ neural activ scale | D000067917;D012984 | T170;T066;T073;T090 |
34,666,314 | choos appropri anticoagul cancer associ thrombosi venous thromboembol diseas fatal complic cancer despit advanc prevent thousand patient requir treatment cancer associ thrombosi cat year guidelin advoc low molecular weight heparin lmwh prefer anticoagul cat year base clinic trial data show lmwh associ lower risk recurr thrombosi compar vitamin k antagonist howev potenti pain subcutan administ lmwh inject expens clinic practic consist guidelin recommend recent studi compar lmwh direct oral anticoagul doac manag cat base promis trial result outlin review doac prefer anticoagul cat occur patient without gastric gastroesophag lesion patient gastrointestin cancer may higher risk hemorrhag doac lmwh remain anticoagul choic appli latest data rapid evolv field care divers patient group challeng articl provid evid base review outpati anticoagul select lower extrem deep vein thrombosi pulmonari embol set cancer take account special popul cancer | D009369;D013927;D054556;D020246 | T047;T191;T046 |
34,666,313 | cancer associ venous thromboembol diseas version nccn clinic practic guidelin oncolog nccn clinic practic guidelin oncolog nccn guidelin cancer associ venous thromboembol diseas focus prevent diagnosi treatment patient cancer develop risk develop venous thromboembol vte vte signific concern among cancer patient heighten risk develop well die diseas manag patient cancer vte often requir multidisciplinari effort treat institut nccn panel compris specialist various field cardiolog hematologyhematolog oncolog intern medicin intervent radiolog medic oncolog pharmacologypharmaci surgerysurg oncolog articl focus vte prophylaxi medic surgic oncolog inpati outpati discuss risk factor vte develop risk assess tool well manag method includ pharmacolog mechan prophylact contraind therapeut intervent special dose requir also discuss | D009369;D054556;D020246 | T191;T047;T046 |
34,666,312 | nccn guidelin insight geneticfamili high risk assess colorect version identifi individu hereditari syndrom allow time cancer surveil opportun risk reduct syndrom specif manag establish criteria hereditari cancer risk assess allow identif individu carrier pathogen genet variant nccn guidelin geneticfamili high risk assess colorect provid recommend assess manag patient risk diagnos high risk colorect cancer syndrom nccn geneticfamili high risk assess colorect panel meet annual evalu updat recommend base clinic expertis new scientif data nccn guidelin insight focus famili adenomat polyposi fap attenu famili adenomat polyposi afap syndrom consider manag duoden neoplasia | D011125;D015179 | T191;T047 |
34,666,310 | target therapi young adult novel epithelioid tumor driven prrcb alk fusion case report describ year old woman unusu epithelioid tumor omentum novel prrcb alk fusion although atyp patholog featur rais signific diagnost challeng express cd tumor cell detect alk rearrang provid critic inform select target therapi patient suitabl surgic resect despit initi promis therapeut respons patient die efficaci treatment confirm lack viabl tumor cell autopsi case highlight role time target therapi patient rare tumor novel action molecular target | D012509 | T191 |
34,666,302 | pentoxifyllin effect hospit patient covid random doubl blind clinic trial pentoxifyllin ptx broad spectrum properti anti inflammatori anticoagul antivir effect aim studi evalu efficaci safeti ptx hospit patient covid doubl blind placebo control random clinic trial conduct hospit patient covid recruit patient random assign ptx group placebo group intervent group receiv ptx capsul dose mg three time day day along nation regimen includ interferon plus lopinavirritonavir hydroxychloroquin primari outcom improv clinic score secondari outcom hand improv inflammatori oxid stress factor hospit complic total patient met inclus criteria individu complet studi analyz signific differ shown demograph baselin clinic characterist clinic score signific two group p day respect although mean serum level interleukin il glutathion chang signific day ptx group p p icu admiss intub hospit stay differ two group result studi show superior ptx placebo improv clinic outcom patient covid although ptx benefici effect il show accept safeti profil offer clinic benefit covid complic | D000086402 | T005 |
34,666,301 | valu structur brain imag explain individu differ children arithmet fluenci differ measur brain structur correl individu differ arithmet fluenci paper build two previous publish studi individu differ children arithmet fluenci correl measur white polspoel et al grey matter polspoel et al one sampl children combin brain imag data two studi measur cognit abil shown predict arithmet fluenci ie numer magnitud process work memori rapid automat name ran allow us investig extend observ structur brain imag measur uniqu correl children arithmet fluenci top well top abovement cognit variabl particip typic develop year old measur ad hierarch multipl regress model regress model show white matter integr right inferior longitudin fasciculus cortic complex left postcentr gyrus remain uniqu predictor individu differ arithmet abovement cognit variabl taken account indic structur neuroimag measur explain individu differ arithmet perform mere account relev cognit predictor | D007206;D066127 | T023;T024;T054 |
34,666,300 | rapid automat categor facial express chang high variabl natur imag emot express quick automat read human face natur view condit yet categor facial express typic measur experiment context homogen set face stimuli evalu basic facial emot fear disgust happi anger surpris sad rapid automat categor face vari head orient light condit ident gender age ethnic origin background context high densiti electroencephalographi record particip view sequenc natur variabl imag neutral express face altern hz rate everi five stimuli hz variabl natur imag one six basic express present despit wide physic variabl across imag signific f hz respons harmon eg f hz etc observ express chang group level everi individu particip facial categor respons found main occipito tempor site distinct hemispher later cortic topographi accord differ express specif stronger respons found sad categor especi left hemispher compar fear happi togeth right hemispher domin categor fear face import differ specif upright face rule contribut low level visual cue overal observ point robust rapid automat facial express categor process human brain | D005149;D000066499 | T033;T041 |
34,666,299 | relat account visual short term memori vstm visual short term memori vstm import resourc allow temporarili store visual inform current theori posit elementari featur eg red green encod store independ vstm howev difficulti explain similar effect similar item rememb better dissimilar item experi test n whether similar effect may due store item context depend manner vstm eg reddestyellowest item line relat account vstm found similar effect due featur similar enhanc sensit detect chang relat colour memoris item chang eg reddest reddest item item underw chang retain relat colour eg still reddest experi n show vstm load index cda amplitud eeg smaller colour order relationship colour order requir encod differ relat colour report two new effect vstm relat detect advantag describ enhanc sensit relat chang chang detect relat cda effect reflect vstm load index cda scale number differ relat featur memori item find support relat account vstm question view vstm store featur colour independ | D008570;D014796 | T041 |
34,666,298 | seem confin electrophysiolog evid periperson space remap follow tool use human periperson space pps special portion space immedi surround bodi integr tactil stimuli deliv bodi auditori visual event eman environ occur interest pps widen tool employ interact object far space howev electrophysiolog evid tool use depend plastic human brain scarc seri three experi particip ask respond tactil stimuli deliv right hand either isol unimod condit combin auditori stimul could occur near bimod near far stimul hand bimod far accord multisensori integr spatial rule bimod stimuli present locat expect respons enhanc respons time rt facilit event relat potenti erp super addit experi verifi rt facilit driven bimod input spatial congruenc independ auditori stimulus intens experi show bimod task effect elicit magnif erp bimod condit signific larger respons near compar far condit experi main experi explor tool use driven pps plastic audio tactil task perform either follow tool use min reach task perform use cm long rake control cognit train min visual discrimin task perform far space follow control train faster rts greater super addit erp found bimod near compar bimod far condit replic experi result crucial far near differenti respons signific reduc tool use altogeth result indic select effect tool use remap extend boundari pps present find might consid electrophysiolog evid tool use depend plastic human brain | D053001;D055698 | T041;T053 |
34,666,297 | role stimulus base cue conceptu inform process facial express emot face shape surfac textur two import cue aid percept facial express emot addit percept also influenc high level emot concept across two studi use represent similar analysi investig relat role shape surfac conceptu inform percept categoris neural represent facial express studi particip complet perceptu task design measur perceptu similar express pair categor task design measur confus express pair assign emot label face use represent similar analysi construct three model similar emot use distinct inform two model base stimulus base cue face shape surfac textur one model base emot concept use multipl linear regress found behaviour task relat similar emot concept model base face shape relat behaviour perceptu task categor model base surfac textur relat behaviour categor perceptu task studi particip view facial express undergo fmri allow measur brain represent geometri facial express emot three core face respons region fusiform face area occipit face area superior tempor sulcus region involv theori mind medial prefront cortex across four region represent distanc facial express pair relat similar emot concept either stimulus base cue togeth result highlight import top influenc high level emot concept behaviour task neural represent facial express | D003463;D005149 | T033;T078 |
34,666,296 | food wast anaerob digest fertil agronom properti untreat digest biochar filter digest residu anaerob digest produc larg quantiti digest product potenti appli organ fertil untreat anaerob digest ad may contain phytotoxin larg volum ad make transport storag difficult studi explor two relat inexpens process method improv agronom perform ad fertil via veget cultiv experi first investig effect dilut ad perform use four leafi veget chines spinach water spinach chines cabbag lettuc optim concentr ad vv ml applic per singl plant pot four veget base shoot fresh weight compar control treatment use commerci fertil ad applic also introduc synergistet bacteria grow medium overal bacteri divers composit similar control treatment consid nutrient separ liquid solid fraction ad need reduc volum experi recoveri nutrient liquid solid fraction filter ad use two type wood base biochar g biochar l ad appli ad biochar residu side dress ww type biochar achiev yield compar treatment use commerci fertil three veget test kale lettuc rocket salad result show dilut biochar filtrat improv agronom perform ad make sustain substitut commerci fertil | D002606;D005308 | T121;T073;T196;T109 |
34,666,295 | predict organ matter access complex anaerob digest character proper assess fate organ matter qualiti anaerob digest organ carbon miner soil requir organ matter qualiti base access complex employ success classifi substratedigest pair princip compon hierarch cluster analysi two first compon explain variabl four main group separ accord feedstock type decreas access increas complex access fraction notic besid increas non biodegrad compound global observ anaerob digest observ trend convers organ matter anaerob digest allow fill gap model anaerob digest process chain inde partial least squar regress accur predict organ matter qualiti digest input r q although digest oper condit temperatur hydraul retent time non explic enough novel approach predict digest qualiti use feed partial least squar regress model previous develop predict organ carbon miner soil combin model predict experiment organ carbon miner soil r model qualiti similar model organ carbon miner soil r first studi success conceiv addit step predict organ matter fate raw substrat anaerob digest soil carbon miner | D000383;D012987 | T167;T090 |
34,666,294 | activ zero valent zinc assist cu ii organ remov perform mechan studi propos method activ acceler corros process zero valent zinc zvz assist cu ii promot consecut product reactiv oxygen speci mechan reactiv oxygen speci generat clarifi metronidazol mtz target pollut outcom suggest associ cu zvz present appar cooper activ enhanc mtz remov attain zvzcu system min compar zvz analysi mechan involv indic improv due addit cu acceler corros zvz addit quench experi electron paramagnet reson epr technolog show superoxid radic result rapid mtz degrad primari compon liabl activ certain amount h generat verifi zvz moreov cu detect zvzcu system aris direct reduct pathway driven zvz indirect reduct pathway driven activ hydrogen atom | D006861;D015032 | T121;T123;T130;T196;T197 |
34,666,293 | ultra high sensit electrochemiluminesc aptasensor pb detect base synergist signal amplif strategi quencher absciss g quadruplex generat signal amplif provid effect way improv detect perform herein ultrasensit electrochemiluminesc ecl aptasensor pb detect develop base dual signal amplif strategi absciss quencher generat g quadruplex one step simultan way nitrogen dope carbon quantum dot link complementari dna cdna ncqds sens interfac appli quencher tris dicarboxyl acid bipyridyl ruthenium ii ru dcbpi tripropylamin system minim ecl signal due intermolecular hydrogen bond induc energi transfer process upon addit pb specif bind aptam trigger absciss cdna ncqds accompani format g quadruplex surfac electrod amplifi intens light emiss ecl amplif effici induc two mechan valuabl greater sum valu synergist effect result high detect sensit ecl aptasensor allow therebi obtain pb measur rang fm nm ultra low detect limit fm pb mediat synergist signal amplif ecl strategi provid new approach integr various amplif strategi | D052157;D015374;D053768;D045663 | T059;T114;T073;T075 |
34,666,291 | raman imag maldi ms toward identif microplast generat use stationeri marker characteris microplast still challeng particular sampl mixtur complex background ink mark paper address challeng develop compar two approach raman imag combin logic base princip compon analysi pca base algorithm ii matrix assist laser desorptionionis mass spectrometri maldi ms found accord raman signal plastic identifi complet shield background raman imag extract plastic signal visualis distribut direct help logic base pca base algorithm via fingerprint spectrum ii raman signal shield mask background maldi ms effect captur identifi plastic polym via barcod mass spectrum link monom overal raman imag maldi ms benefit limit microplast analysi access combin use two techniqu general recommend especi assess sampl strong background interfer | D000080545;D010969 | T167;T122 |
34,666,290 | classif drug evalu drug interact drug develop clinic manag new drug develop clinic drug interact studi carri accord mechan potenti drug interact evalu vitro studi obtain inform provid effici medic expert packag insert various inform materi drug launch recent updat japanes guidelin present general procedur consid scientif valid present moment review aim highlight viewpoint japanes guidelin enumer drug involv anticip involv evid pharmacokinet drug interact classifi clearanc pathway potenti intens base systemat review literatur classif would inform design clinic studi develop stage appropri manag drug interact clinic practic | D000076722;D004364 | T091;T062;T121 |
34,666,289 | net anatom inform lesion wise loss function integr neural network multipl sclerosi lesion segment accur detect segment multipl sclerosi ms brain lesion magnet reson imag import diseas diagnosi treatment challeng task lesion vari great size shape locat imag contrast object studi develop algorithm base deep convolut neural network integr anatom inform lesion wise loss function net fast accur autom segment ms lesion distanc transform map use construct convolut modul encod lesion specif anatom inform overcom lesion size imbal network train improv detect small lesion lesion wise loss function develop individu lesion model sphere equal size isbi longitudin ms lesion segment challeng dataset subject total net achiev overal score amongst top perform method larger cornel ms dataset subject total net signific improv voxel wise metric dice improv p valu rang p p auc voxel wise precis recal curv improv lesion wise metric lesion wise f score improv p valu p auc lesion wise roc curv improv compar lead public avail ms lesion segment tool | D009103 | T047 |
34,666,288 | three dimension quadricep vector parallel spheric axi japanes varus osteoarthrit knee quadricep femori may reliabl refer proper align total knee arthroplasti tka previous show quadricep vector qv parallel spheric axi sa center hip center medial condyl healthi knee purpos studi determin whether qv parallel sa knee varus osteoarthr oa | D020370;D052097 | T023;T047 |
34,666,287 | effect tick communiti assemblag ectoparasit deer mice ectoparasit fundament ecosystem play key role trophic regul flea mite tick common hematophag ectoparasit infest share mammalian host one common host ontario canada deer mous peromyscus maniculatus climat warm geograph rang blackleg tick ixod scapulari american dog tick dermacentor variabili expand introduct new ecosystem may alter current ectoparasit communiti three differ site exposur tick vari term tick divers abund ectoparasit communiti structur found deer mous host examin focus speci co occurr habitat partit host predict tick speci preval tick would domin micro habitat attach site often inhabit parasit therebi signific alter parasit communiti structur result suggest blackleg tick american dog tick could posit associ negat random associ ectoparasit speci even occupi attach site sampl site play signific role communiti assemblag well possibl due differ tick exposur tick rang expand becom abund import understand preval potenti alter dynam ectoparasit communiti affect transmiss pathogen may spread within ecosystem one host anoth | D018884;D005423 | T204 |
34,666,285 | effici approach probe bioactiv transderm compon tradit chines herbal patch uhplc ms gutong patch case tradit chines herbal patch tchps character good patient adher side effect wide use clinic howev bioactiv transderm compon key qualiti efficaci rare investig | D004365;D053719 | T121;T063;T123 |
34,666,284 | benefici effect escin muscl regener rat model skelet muscl injuri recent advanc understand escin action provid basi new therapeut claim drug escin evok attenu nf b depend signal increas mmp decreas coup tfii content rise cholesterol biosynthesi could benefici allevi muscl damag process | D004928;D018482 | T024;T023;T121;T109 |
34,666,283 | optim surfac modif silicon nanowir field effect transistor polyethylen glycol microrna detect microrna mirna sens play essenti role diagnosi sever diseas especi cancer appropri intervent treatment howev quantifi mirna demand high sensit select assay distinguish analog sequenc low abund bio sampl determin wide rang concentr report present novel techniqu satisfi requir modifi silicon nanowir field effect transistor sinwfet compon mix self assembl monolay msam polyethylen glycol peg differ ratio silan peg nh silan peg oh glutaraldehyd immobil dna probe mirna detect biomark sever type cancer empir result reveal fabric peg sinwfet dna biosensor could quantifi mirna within fm pm especi one modifi silan peg nh silan peg oh exhibit outstand perform recogn mirna ultra low concentr dynam rang order magnitud pm approach conveni analyt competit cost effect comparison current use method nucleic acid test label amplif free characterist therefor feasibl mirna detect sinwfet base biosensor also potenti clinic applic diseas diagnosi oligonucleotid biomark | D015374;D035683;D053770 | T073;T123;T114;T075;T059 |
34,666,282 | atf regul oxid stress extracellular matrix degrad via pnrf signal pathway pelvic organ prolaps pelvic organ prolaps pop common disord women character weaken pelvic support structur extracellular matrix ecm degrad activ transcript factor atf upregul anterior vagin wall tissu pop patient hypothes upregul atf might contribut pop develop studi aim unveil role atf pathogenesi pop use h induc vitro model vagin fibroblast isol woman pop q stage greater ii asymptomat women normal pelvic floor support knockdown atf enhanc cell viabil decreas cell apoptosi flow cytometri immunnofluoresc show atf defici inhibit h induc ros product express ohdg hne western blot real time pcr analysi reveal atf defici attenu ecm compon degrad increas collagen collagen iii elastin mmpstimp imbal decreas mmp mmp increas timp moreov knockdown atf induc activ pnrfho signal pathway treatment p inhibitor sb abolish protect atf defici h induc cell damag revert nrf activ tbhq thus atf like contribut pop progress induc cell apoptosi oxid stress ecm degrad via regul pnrf pathway provid potenti therapeut target pop | D018384;D015398 | T049;T044;T043 |
34,666,281 | alter immedi behavior respons partial social exclus cross diagnost studi patient borderlin person disord persist depress disord borderlin person disord bpd persist depress disord pdd relat interperson dysfunct might becom particular appar situat social exclus se emot respons se wide explor behavior data clinic sampl lack cross diagnost studi appli variant cyberbal paradigm investig dynam behavior respons partial se bpd pdd bpd patient n pdd patient n age gender match healthi control hc total n play experiment ie partial se cyberbal control ie inclus condit random order group tend increas ball toss toward exclud respons se behavior turn signific lower pdd p trendwis bpd patient p thus alter immedi respons partial se observ bpd pdd addit emot reaction studi support hypothesi behavior cope se bpd pdd might problemat long run provid experiment paradigm futur research interperson dysfunct | D001883;D003866 | T048 |
34,666,280 | slow releas zn applic zn chitosan nanoparticl wheat intensifi sourc activ sink strength sourc activ sink strength import aspect measur growth yield wheat despit zinc extend function amend plant metabol activ critic research find miss map elus interplay slow releas zinc zn applic nanoparticl nps crop plant present studi report slow releas zn applic zn chitosan nps bestow myriad effect sourc activ sink strength wheat plant herein effect foliar applic zn chitosan nps wv boot stage wheat crop evalu quantifi sourc sink potenti compar znso zn chitosan nps endow elev sourc activ regul cellular redox homeostasi improv antioxid status cellular stabil higher photosynthesi cognat field experi nps wv signific spur sink strength regul starch biosynthesi enzym viz sucros synthas sus invertas inv adp glucos pyrophosphorylas agpas solubl starch synthas sss accumul starch develop wheat grain concomit higher spike length without awn signific higher number grainsspik test weight znso treatment yield znso treatment biolog yield harvest index quantifi higher sink size valid better sink strength slow releas zn applic via chitosan nps | D048271;D053758;D013214 | T116;T121;T073;T109;T126 |
34,666,279 | specif glutathion transferas ensur effici detoxif diclofenac solanum lycopersicum l plant diclofenac dcf common pharmaceut due high use low remov rate consid promin contamin surfac groundwat worldwid studi solanum lycopersicum l cv micro tom tomato use disclos role glutathion gsh relat enzym gsh conjug dcf well report detoxif mechan mammal plant speci achiev lycopersicum plant expos mg l dcf week semi hydropon experi result obtain point toward effici dcf detoxif mechan prevent dcf bioaccumul fruit minim concern human health although system respons seem present respons dcf current data also show detoxif most root specif process furthermor appear gsh mediat dcf detoxif main mechan activ glutathion transferas gst activ great enhanc root tomato plant treat mg l dcf accompani increas glutathion reductas activ respons gsh regener appli target gene express analysi provid evid first time slgstf slgstf gene code gsts phi class main player drive conjug contamin sens even though tomato plant appear somewhat toler dcf exposur research gst activ prove instrument remedi dcf contamin environ improv plant growth condit | D018551 | T002;T168 |
34,666,278 | prevent transit regret institut ethnographi gender affirm medic care assess practic canada person open regret gender transit detransit bolster within medic communiti impress transgend non binari tran peopl requir close scrutini seek hormon surgic intervent despit low preval regret patient experi scant empir research detransit rare transit outcom profound organ gender affirm medic care enterpris inform tenet institut ethnographi examin routin gender affirm care clinic assess practic canada interview clinician administr tran patient total n review healthcar document pertin gender affirm care canada analysi uncov pervas regret prevent techniqu includ requir tran patient undergo extens psychosoci evalu prior transit clinician leverag psychiatr diagnos proxi predict transit regret case delay deni medic treatment identifi case patient dissatisfact surgic result person detransit account decoupl transit regret detransit particip endors stricter clinic assess trace clinic work prevent regret cisnorm transnorm medicin togeth construct regret life end turn drive clinician appli strategi mitig perceiv risk malpractic legal action treat tran peopl specif yet attempt prevent outcom contrast materi healthcar need tran peopl conclud regret detransit unpredict unavoid clinic phenomena rare appear life end form critic research experi peopl detransit necessari bolster comprehens gender affirm care recogn dynam transit trajectori address clinician fear legal action cisgend anxieti project onto tran patient seek medic care | D005783;D063106 | T032;T098;T041 |
34,666,277 | gender relationship matern depress adolesc intern symptom well establish adolesc whose mother depress like experi intern symptom eg depress anxieti symptom even extens work show intern symptom preval among adolesc girl compar boy unclear matern offspr mental health relationship gender neutral gender specif matern depress act equal forc adolesc risk intern symptom contribut adolesc gender differ studi analyz whether adolesc gender moder associ matern depress adolesc intern symptom use data year survey fragil famili child wellb studi follow cohort children born larg us citi primarili unmarri parent sampl primari caregiv mother adolesc offspr age year numer social risk factor intern symptom afford opportun care assess possibl gender natur mother adolesc linkag adjust ordinari least squar regress model show matern depress associ signific higher adolesc depress anxieti symptom howev relationship matern depress adolesc intern symptom substanti larger daughter compar son gender natur concurr mother adolesc symptom highlight need consid effect gender risk process within famili moreov strong cluster intern symptom among mother daughter highlight valu prevent treatment effort attend adult adolesc mental health simultan | D003863;D009034 | T048;T184;T054 |
34,666,276 | effect tumor size metastat extent efficaci first line pembrolizumab monotherapi patient high pd l express advanc nsclc tumor tumor size metastat extent may influenc tumor respons immunotherapi non small cell lung cancer nsclc aim studi examin relationship baselin sum longest diamet bsld number metastat organ nmo tumor respons pembrolizumab second aim analyz associ baselin sld nmo progress free surviv pfs overal surviv os | D002289;D008175 | T191 |
34,666,275 | trpc underestim univers pacemak channel transient receptor potenti channel canon trpc cation channel poor ca select signific constitut activ one channel featur strike abil coupl surpris versatil manner differ stream signal pathway therebi serv cellular function tissu specif manner express protein promin excit cell activ repeat implic electr pacemak previous studi demonstr linkag constitut activ trpc neuron fire hippocampus cerebellum recent report park laboratori corrobor concept trpc function critic element neuron pacemak machineri dopaminerg neuron substantia nigra conclus mechanist coupl trpc activ fire frequenc appear evid differ type neuron highlight potenti trpc univers well multifunct pacemak channel | D015398;D050052 | T043;T044;T116;T123 |
34,666,273 | earli subthalam nucleus deep brain stimul parkinson diseas reduc long term medic cost subthalam nucleus stn deep brain stimul dbs recogn safe effect treatment mid advanc stage parkinson diseas pd decreas need pd medic associ cost studi report medic cost clinic trial evalu dbs patient earli stage pd project cost advanc stage diseas | D046690;D017048 | T061;T081 |
34,666,271 | analysi urinari organ acid gas chromatographi tandem mass spectrometri method metabol profil applic sensit accur precis method develop quantif larg number organ acid human urin gc msms analyt select base role key metabol intermedi intermedi kreb cycl fatti acid oxid glycolysi stream metabolit neurotransmitt synthesi degrad metabolit indic nutrit defici byproduct microbi activ gastrointestin tract gi etc effici sampl prepar protocol select base test extract differ solvent mtbe ethyl acet acid condit wherea final general protocol appli methanol regard derivat methoxyamin mstfa tmcs appli method extens valid includ stabil studi ensur accur determin studi organ acid human urin proof util exhibit set sampl human volunt method find wide applic context metabolom clinic nutrit studi | D055432;D053719 | T091;T063 |
34,666,270 | amphiphil triblock copolym gas chromatograph stationari phase high resolut perform toward wide rang isom compon lemon essenti oil work present investig use amphiphil triblock copolym compos poli ethylen oxid peo poli propylen oxid ppo poli ethylen oxid peo denot epe stationari phase gas chromatograph gc analys epe capillari column exhibit moder polar column effici platesm determin naphthalen c k differ peg polysiloxan homopolym show high resolut perform toward wide rang aliphat aromat isom term polar acid base properti particular epe column display distinct advantag separ critic isom alkan anilin phenol compon lemon essenti oil commerci peg polysiloxan column addit epe column exhibit excel separ repeat reproduc relat standard deviat rsd valu rang run run day day column column respect moreov epe column investig term thermal stabil minimum allow oper temperatur miaot sampl loadabl applic gc ms analysi essenti oil demonstr feasibl practic analys work demonstr promis futur triblock copolym new class select stationari phase gc analys bare report date find work import valu fundament research practic applic | D009822 | T109 |
34,666,269 | separ minor cannabinoid hemp extract trap multipl dual mode liquid liquid chromatographi asid tetrahydrocannabinol thc cannabidiol cbd less common cannabinoid recent gain increas popular most due promis biolog potenti howev time save cost effect method prepar purif miss studi trap multipl dual mode mdm flow revers liquid liquid chromatographi llc oper mode use separ differ minor cannabinoid hemp extract separ task specif biphas solvent system select purif target constitu follow n hexanemethanolwat cannabielsoin cbe n hexanemethanolwat cannabidivarin cbdv cannabigerol cbg n hexanemethanolwat cannabinol cbn n hexanemethanolwat cannabichromen cbc cannabicylol cbl separ task concentr hemp extract feed stream mobil phase flow rate select shake flask stationari phase retent experi respect determin trap mdm oper paramet short cut method implement follow equilibrium cell model base simul trap mdm allow separ target cannabinoid puriti yield solvent consumpt fold lower product almost doubl obtain use batch separ | D002186;D002188 | T167;T121;T002;T109 |
34,666,268 | microfluid high throughput solut chromatograph process develop complex multimod chromatographi use proof concept high throughput technolog fundament expedit implement novel purif platform possibl perform process develop within short period time save consum biolog materi prime featur high throughput screen devic work microfluid devic evalu high throughput solut complet studi chromatograph oper condit ten differ multimod resin potenti class purif solut general hinder complex take consider microfluid platform herein appli assess tool high throughput applic commerci avail multimod ligand studi bind three antibodi base biomolecul polyclon mixtur whole antibodi fab fc fragment differ ph salt condit total experi result obtain microfluid devic compar standard well filter micropl high throughput tool addit five ten multimod ligand test pack bench scale column perform final valid microfluid result obtain data acquir work use differ screen protocol corrobor show microfluid chromatographi valuabl tool fast implement new purif step particular goal narrow downstream possibl first point decis | D002845;D044085 | T059;T090 |
34,666,267 | onlin sampl pretreat analysi decomposit product lithium ion batteri liquid chromatographi hyphen ion trap time flight mass spectrometri induct coupl plasma sector field mass spectrometri lithium ion batteri essenti power sourc mobil electron devic like cell phone tablet increas use field electromobl energi transit common appli liquid electrolyt commerci cell contain conduct salt relat high concentr lipf moll analyt batteri electrolyt investig necessari protect column mass spectromet salt precipit clog thus dilut sampl necessari result higher limit detect limit quantif studi comprehens onlin sampl prepar approach revers phase liquid chromatographi onlin solid phase extract develop allow higher inject volum lower dilut factor method develop onlin solid phase extract pristin electrolyt use trimethyl phosphat triethyl phosphat model substanc organo fluoro phosphat weak strong retent extract column organo fluoro phosphat potenti hazard decomposit product due structur similar chemic warfar agent like sarin therefor quantif benefici toxicolog assess optim chromatograph paramet perform use electrochem age electrolyt substanc independ quantif plasma base techniqu isocrat separ method implement use optim condit lipf could remov quantit inject volum increas factor dilut factor could decreas factor ten eleven differ organo fluoro phosphat overal concentr mgkg found therefor limit detect limit quantif improv signific loq g kg phosphorus content lod g kg phosphorus content summari fast onlin sampl prepar liquid chromatograph investig lithium ion batteri electrolyt implement valid electrochem age lithium ion batteri electrolyt | D011211;D008094 | T196;T121;T073 |
34,666,266 | spectrophotometr fluorometr detect dnabsa interact antimicrobi anticanc antioxid catalyt activ biolog activ methoxi substitut pyrimidin ligand cap copper nanoparticl new schiff base ligand dpmn synthes condens hydroxi nitrobenzaldehyd amino dimethoxypyrimidin confirm spectroscop analyt method solid air stabl copper nanoparticl dpmn cunp synthes copper chlorid salt stabil prepar schiff base ligand phase transfer assist synthesi modifi brust schiffrin techniqu format ligand stabil copper nanoparticl confirm uv visibl ft ir spectroscop techniqu size surfac morpholog qualiti dpmn cunp analyz sem tem techniqu antioxid activ dpmn dpmn cunp dpph sod peroxid nitrous oxid analyz electron absorpt spectroscopi dna interact dpmn dpmn cunp ct dna carri use electron absorpt fluoresc viscometr measur cyclic voltammetr techniqu interact bsa synthes compound analyz electron absorpt spectroscopi antimicrobi studi confirm synthes dpmn cunp possess signific biolog activ dpmn anticanc result suggest prepar dpmn cunp signific anticanc activ differ cancer cell line least toxic effect normal nhdf cell line posit respons biolog evalu dpmn cunp possess good catalyt activ methyl orang reduct methylen blue degrad nitro phenol reduct | D000890;D000970;D053768 | T121;T073;T109 |
34,666,265 | high select sensit detect glutathion cystein homocystein turn fluoresc biosensor base cysteamin stabil cdte quantum dot work cysteamin ca stabil cdte quantum dot qds ca cdte qds sodium citrat stabil gold nanoparticl aunp prepar strong electrostat interact spectral overlap emiss spectrum ca cdte qds absorpt spectrum aunp high effect fluoresc reson energi transfer fret system form fluoresc ca cdte qds strong quench synthes ca cdte aunp self assembl larg cluster due electrostat attract fluoresc ca cdte sharpli quench result fret optimum ph posit gsh could assembl negat aunp electrostat interact destroy fret system ca cdte aunp due red shift absorpt wavelength aunp caus aggreg fluoresc ca cdte recov recov fluoresc effici show linear function gsh concentr nm detect limit nm quench emiss ca cdte could recov attribut aggreg aunp gsh optim condit sens system success appli detect gsh real human blood plasma sampl recoveri show promis futur high sensit select gsh detect human blood plasma sampl | D015374;D019187;D053768;D045663 | T059;T073;T197;T075 |
34,666,264 | function approach character safeti risk signal intersect movement level exploratori analysi safeti evalu signal intersect often conduct develop statist data driven method base data aggreg certain tempor spatial level eg year hour per signal cycl intersect approach leg howev aggreg subject major simplif mask under spatio tempor safeti risk pattern within data aggreg level consequ high resolut analysi safeti risk within signal cycl traffic movement level perform studi contribut literatur propos new function data analysi fda approach novel character safeti risk pattern signal intersect function data smooth method mitig overfit account nonneg characterist safeti risk propos model time seri safeti risk within signal cycl traffic movement level function analysi varianc method fanova compar group level differ function curv use test differ safeti risk function among differ traffic movement typic signal intersect repres signal type channel select studi locat approxim hour traffic video data record unman aerial vehicl use extract traffic conflict new movement level safeti risk pattern character base safeti risk function reveal tempor distribut risk within signal cycl test traffic movement signific distinct function risk pattern accord fanova result risk pattern traffic movement differenti base data aggreg cycl approach level propos function approach potenti use facilit proactiv safeti manag calibr microsimul model safeti evalu optim signal time consid traffic safeti disaggreg level | D000063;D001334 | T056;T037;T067 |
34,666,263 | biofilm growth continu uvc irradi quantit effect growth condit growth time intens respons paramet biofilm harbor wide rang microorgan includ opportunist respiratori pathogen establish engin surfac pose risk public health industri emerg compact germicid ultraviolet light emit diod uv led may enabl incorpor confin space inhibit bacteri surfac colon inaccess surfac premis plumb applic necessit knowledg quantit respons biofilm growth rate uv exposur continu irradi surfac herein perform experi vari flow cell temperatur order control baselin biofilm growth rate absenc uv biofilm growth compar condit simultan uvc irradi inhibit effect uv irradi biofilm growth kinet diminish favor growth condit higher temperatur increas temperatur c result increas biovolum uvc nm intens wcm fit exist intens respons model biofilm growth data analyz effect temperatur model paramet consist hypothes shield effect aris deposit extracellular colloid materi shield effect found result breakthrough behavior irradi biofilm h wherein accumul shield substanc eventu enabl biofilm establish even relat high irradi intens wcm respect applic uvc irradi biofilm prevent result impli surfac prone bacteri colon requir disproportion higher intens uvc irradi prevent biofilm establish continu surfac irradi may inadequ sole intervent biofilm prevent mani scenario | D004203;D014466 | T070;T061 |
34,666,262 | examin effect prenat alcohol exposur corticothalam connect multimod neuroimag studi children children fetal alcohol spectrum disord fasd experi rang cognit behavior effect prior studi demonstr white matter chang children fasd relat typic develop control tdc chang relat behavior prior meg studi candelaria cook et al demonstr reduc alpha oscil rest fasd relat tdc alpha power correl behavior howev littl known brain structur influenc brain function hypothes alpha power relat corticothalam connect children year age tdc n fasd n underw rest meg eye open close mri collect structur diffus tensor imag data meg spectral analysi perform sensor sourc data estim mean fraction anisotropi region interest roi includ corticothalam tract fasd group reduc mean fa three corticothalam roi fa tract signific correl alpha power sensor sourc level result support hypothesi integr corticothalam tract influenc cortic alpha power research need understand brain structur function influenc behavior | D063647;D011297;D066127 | T023;T047;T019;T037;T024 |
34,666,261 | advanc glycat end product potenti trigger factor self reactiv myelin antigen multipl sclerosi multipl sclerosi ms demyelin autoimmun diseas autoreact lymphocyt infiltr central nervous system cns react antigen deriv protein myelin sheath reason lymphocyt recogn certain myelin antigen exogen activ autoimmun respons remain unknown repres key understand pathogenesi ms neuron character elev glycolyt metabol methylglyox mg high reactiv oxoaldehyd spontan form product glycolysi react protein nucleotid phospholipid form stabl adduct call advanc glycat end product age sever studi demonstr mg deriv age accumul plasma brain ms patient furthermor evid post myelin oligodendrocyt myelin form glial cell increas glycolyt metabol maintain surviv function like explain progress accumul mg ms lesion hypothesi propos mg deriv age accumul protein compos myelin sheath respons alter antigen present process mimick exogen antigen trigger autoimmun respons hypothesi experiment confirm new pathogen mechan ms identifi | D009103;D009186 | T026;T047;T024 |
34,666,260 | genet link keratoconus fuch endotheli corneal dystrophi keratoconus kc noninflammatori bilater progress corneal stromal thin disord lead corneal ectasia central anterior corneal stromal scar irregular myopic astigmat reduc visual acuiti fuch endotheli corneal dystrophi fecd bilater sporad autosom domin non inflammatori dystrophi involv corneal endothelium dystrophi evolv major complaint includ glare halo reduc visual acuiti rare patholog co exist patient initi report kc fecd near case coexist report literatur till report number case vari region region major case document famili histori henc difficult approxim incid preval base avail literatur henc hypothes patholog probabl genet link avail literatur support hypothesi discuss also discuss various probabl mechan coexist propos manag algorithm assess attempt surgeri patient also propos patient must undergo genet screen counsel prevent spread patholog futur generat | D005642;D007640;D009216 | T047 |
34,666,259 | river postnat psychosi qualit studi women experi mean paper report find studi women experi postpartum psychosi affect women first four six week follow childbirth previous research report mani women reluc disclos symptom mental ill health healthcar profession although like discuss symptom concern health profession known | D008880;D011618 | T097;T091;T048 |
34,666,258 | synthesi biolog evalu molecular dock new sulfonamid base indolinon deriv multitarget kinas inhibitor leukemia seri novel sulfonamid base indolinon f design synthes cytotox activ evalu panel sixti cancer cell line screen indic fluoro oxoindolin yliden acetyl phenyl benzenesulfon f possess promis cytotox ccrf cem sr leukemia cell line ic valu respect investig leukem cytotox compound f carri perform pdgfr vegfr aurora ab flt enzym assay ccrf cem sr cell cycl analysi investig show compound f exhibit pronounc dual inhibit kinas pdgfr aurora potenc nm respect vitro result support molecular dock studi order explor bind affin key amino acid interact work repres compound f promis anticanc agent leukemia | D062105 | T170;T063 |
34,666,255 | chang omentin chemerin week lifestyl intervent year follow children obes data influenc short term lifestyl intervent children obes long term follow bodi weight adipokin cardiometabol risk paramet scarc | D008019 | T047;T054 |
34,666,249 | three dimension kinemat analysi upper limb movement individu without subacromi shoulder pain explor statist parametr map subacromi shoulder pain ssp account case shoulder pain kinemat alter upper limb observ individu ssp although consensus alter literatur therefor present studi aim compar three dimension kinemat scapula trunk arm shoulder flexion extens abduct adduct movement individu ssp control group use statist parametr map spm evalu particip ssp control group cg three dimension kinemat analysi perform start arm extensionadduct move flexionabduct end return extensionadduct respect group ssp group flex trunk p rotat scapula intern p p rotat upward p p posterior tilt p p less cg group arm abduct adduct arm flexion extens ssp group flex p less trunk rotat upward p less scapula posterior tilt scapula p cg combin convent variabl use describ motion individu ssp minimum maximum valu rang motion result provid spm furnish detail descript compens limit patient enabl better understand function scapular girdl well improv evalu process clinic decis make | D012785;D020069 | T023;T184;T030 |
34,666,248 | suppress quadricep fascicl behavior present surgic limb histori acl reconstruct balanc publish data larg focus adapt muscl fiber size anterior cruciat ligament reconstruct aclr fail account dynam chang behavior muscl contractil element strong contribut forc product better understand sourc quadricep dysfunct purpos research determin alter fascicl behavior present aclr unilater aclr individu mf yrs kg month surgeri healthi control mf yrs kg particip vivo vastus laterali fascicl behavior record use ultrasonographi three maxim isokinet knee extens fascicl length angl shorten veloc calcul analyz rest peak torqu peak knee extens torqu averag isokinet trial nmkg group limb interact assess use separ two way analys varianc evalu compar confid interv appropri signific interact present fascicl angl peak torqu p fascicl length excurs p fascicl angl excurs p fascicl shorten veloc p strength p upon post hoc evalu surgic limb display alter vivo fascicl behavior compar limb p reduc strength compar contralater right control limb p data show histori aclr fascicl slower lengthen less oper lower angl relat axi forc product alter fascicl behavior aclr may import under factor explain protract quadricep dysfunct | D000070598;D059549 | T061;T037 |
34,666,247 | effect handrail cross section design age appli handrail forc reach grasp balanc reaction handrail shown reduc likelihood fall despit common use littl known handrail shape size affect forc peopl appli balanc loss forc correspond abil recov balanc depend age follow rapid platform translat older adult sex match younger adult recov balanc use seven handrail cross section vari shape size younger adult abl withstand higher perturb appli higher forc older adult howev younger adult achiev peak result forc quick may reflect slower rate forc generat older adult consid handrail design mm round handrail allow particip success recov largest perturb enabl highest forc generat convers taper handrail poorest perform result lowest forc generat withstood perturb magnitud find suggest handrail cross section design affect magnitud forc generat may impact success recoveri find inform handrail design recommend support effect handrail use demand balanc recoveri scenario | D018737;D004856 | T040;T081 |
34,666,246 | effect seat height whole bodi movement lower limb muscl power sit stand movement young older individu sit stand sts movement low seat height easili execut older individu although young individu increas lower limb muscl power llmp base product ground reaction forc grf center mass veloc comv sts movement low seat height remain unclear whether seat height effect llmp sts movement older individu present studi aim investig differ llmp sts movement seat height lower young older individu twelv older twelv height match young individu instruct perform sts movement low cm middl cm high cm seat height sts movement grf obtain motion analysi system forc plate low seat height condit forward upward llmps upward comv signific lower older individu young individu forward comv complet time sts movement low seat height signific longer older individu young individu find suggest slower upward comv due lower upward llmp extend complet time sts movement low seat height older individu furthermor low seat height condit older individu may move center mass com forward differ way compar young individu may use forward llmp move com forward | D009068;D011187 | T040;T033 |
34,666,245 | trelagliptin amelior il impair chondrocyt function via ampksox pathway chondrocyt dysregul play critic role develop osteoarthr oa pro inflammatori cytokin interleukin il activ chondrocyt degrad structur extracellular matrix ecm event import mechan oa trelagliptin select inhibitor dipeptidyl peptidas dpp use treatment type diabet mellitus tdm display wide rang anti inflammatori capac effect trelagliptin oa chondrocyt test show trelagliptin mitig il induc product inflammatori cytokin interleukin il interleukin il tumor necrosi factor alpha tnf human chondrocyt trelagliptin amelior il induc oxid stress reduc generat reactiv oxygen speci ros particular presenc trelagliptin prevent il induc reduct acan gene protein aggrecan moreov show trelagliptin restor il induc reduct sox knockdown sox abolish protect effect trelagliptin mechanist demonstr ampk requir amelior trelagliptin sox reduct il collect studi demonstr dpp inhibitor trelagliptin protect effect chondrocyt function trelagliptin may potenti role antagon chondrocyt deriv inflamm oa | D015398 | T043;T044 |
34,666,243 | self supervis ct super resolut hybrid model softwar base method improv ct spatial resolut without chang hardwar scanner increas radiat dose object work aim develop deep learn dl base ct super resolut sr method reconstruct low resolut lr sinogram high resolut hr ct imag mathemat analyz imag process ct sr imag problem synergist integr sr model sinogram domain deblur model imag domain hybrid model sadir sadir incorpor ct domain knowledg unrol dl network sadir net sadir net self supervis network train test singl sinogram sadir net evalu sr ct imag catphan physic phantom real porcin phantom perform compar state art sota dl base ct sr method phantom sadir net obtain highest inform fidel criterion ifc structur similar index ssim lowest root mean squar error rmse modul transfer function mtf sadir net also obtain best result improv mtf mtf compar fbp altern spatial resolut mtf mtf sadir net reach counterpart reconstruct hr sinogram fbp result show sadir net provid perform compar sota method ct sr reconstruct especi case extrem limit train data even data thus sadir method could find use improv ct resolut without chang hardwar scanner increas radiat dose object | D012984;D014057 | T170;T073;T090;T060 |
34,666,242 | sociodemograph clinic factor associ depress anxieti general mental health peopl multipl sclerosi covid pandem background peopl multipl sclerosi pwms may increas risk psycholog distress covid studi self report mental health us pwms covid prior vaccin rollout method cross section survey distribut onlin pwms iconquerm depress anxieti symptom burden general mental health status measur via patient health questionnair general anxieti disord promi global mental health scale linear regress model assess associ mental health variabl age sex disabl status comorbid social determin health result us pwms mean age year standard deviat rang femal relaps remit diseas previous depress diagnosi preval moder sever depress anxieti symptom burden respect endors fairpoor general mental health pwms test posit covid n report higher depress anxieti symptom burden p increas disabl status score social determin health associ depress symptom wors general mental health younger age associ increas depress anxieti symptom burden wors general mental health femal sex associ greater anxieti symptom conclus specif associ wors mental health among pwms covid reflect combin clinic demograph social determin health multidisciplinari care team vigil import address ongo mental health impact covid pwms | D000086382;D009103 | T047;T067 |
34,666,241 | applic definit convers secondari progress ms danish nationwid popul number patient relaps remit multipl sclerosi rrms convert secondari progress sp ms uncertain emerg treatment option spms import identifi rrms patient transit sp phase object present studi character clinic paramet use diseas modifi therapi patient diagnos spms rrms patient alreadi enter sp phase use danish multipl sclerosi registri dmsr | D009103;D020528;D020529 | T047 |
34,666,240 | apprais antigen identif igg effector function drive host immun respons multipl sclerosi increas immunoglobulin g igg antibodi oligoclon band ocb characterist featur multipl sclerosi ms neuroinflammatori demyelin diseas neurodegener chronic stage ocb shown associ diseas activ brain atrophi despit intens research last sever decad antigen specif igg ms remain elus present evid support intrathec igg driven antigen stimul therefor provid reason fail ms antigen identif presenc co deposit igg activ complement product ms lesion suggest igg effector function may play critic role diseas pathogenesi | D009103 | T047 |
34,666,239 | incorpor transcriptom metabolom analysi reveal effect ultrasound ethanol product saccharomyc cerevisia studi report enhanc ethanol yield saccharomyc cerevisia low intens ultrason irradi use fix mode frequenc generat self develop six frequenc khz ultrason devic group sonic treatment ethanol product potenti determin optim condit ultrason treatment ultrason frequenc khz power densiti wl treatment time h maximum ethanol yield increas compar control transcriptom sequenc show ultrason treatment expression regul gene involv pyruv metabol glycolysi pentos phosphat pathway glucos transport reduc power product quantit real time polymeras chain reaction qrt pcr confirm chang gene express regul metabolom reveal ultrason treatment increas intracellular glucos nicotinamid adenin dinucleotid nadh content key metabolit ethanol synthesi besid ultrason treatment decreas acet deriv result lower revers consumpt pyruv thus promot ethanol synthesi chang gene express metabolit content might main reason ethanol yield saccharomyc cerevisia increas ultrason irradi | D012441 | T004 |
34,666,236 | cell cultur normal human mammari gland cultiv monolay mini systemat review mammari gland constitut differ cell type exampl epitheli cell appear target mani studi sinc produc secret milk lactat origin mani human breast cancer mammari gland biolog character dynam tissu growth function regress phase understood main due tissu cultur studi cell cultur probabl one use vitro scientif model common research model still two dimension cultur system differ approach condit test use improv isol growth yield mainten viabil mammari gland cell therefor studi aim explor summar cell cultur techniqu normal human mammari gland cell cultur monolay search strategi conduct use electron databas pubm scopus virtual health librari search carri use keyword cell cultur mammari gland human main search carri two author juli august addit perform review matrix elabor spreadsheet organ systemat inform articl inclus total studi includ review conduct qualit analys although studi cell report sinc found last decad larg carri usa addit possibl verifi human mammari epitheli cell hmec primari cultur obtain breast surgeri main cell type studi cell cultiv dulbecco modifi eagl medium dmem medium divers supplement final divers use dissoci reagent lack inform cryopreserv observ detail methodolog inform studi model would propos investig | D018929 | T059 |
34,666,234 | first report rare rnf variant associ famili moyamoya diseas african american famili investig potenti genet suscept moyamoya diseas mmd african american famili | D000251;D001741;D009072;D044767 | T116;T047;T126;T098 |
34,666,233 | cerebr hyperperfus delay coma recoveri subdur hematoma evacu acut subdur hematoma devast neurolog injuri signific morbid mortal patient larg subdur hematoma result compress under brain later brain shift sever neurolog deficit coma occur emerg neurosurg decompress life save intervent improv mortal neurolog function persist coma despit subdur hematoma evacu often result persist midlin shift cerebr infarct relat initi elev intracrani pressur herniat nonconvuls seizur metabol infecti caus howev subset patient remain comatos without discern etiolog report describ elder patient remain comatos without known caus sever week subdur hematoma evacu found delay cerebr hyperperfus brain imag sever day mark recoveri conscious occur timefram match improv brain imag find cerebr hyperperfus follow subdur hematoma evacu requir investig consid caus persist potenti recover coma | D001921;D003128;D006408 | T047;T023;T046;T048;T037 |
34,666,232 | genet caus under grey matter heterotopia grey matter heterotopia gmh caus seizur associ wide rang neurodevelopment disord syndrom caus failur neuron migrat fetal develop lead cluster neuron reach final destin cerebr cortex perform extens literatur search pubm omim googl scholar provid overview known genet associ periventricular nodular heterotopia pnvh subcort band heterotopia sbh subcort heterotopia subh classifi heterotopia pvnh sbh subh collect genet inform frequenc imag featur salient featur tabl everi subtyp heterotopia result pvnh sbh subh genelocus associ make total gene chromosom loci studi emphas extrem genet heterogen under gmh aid clinician establish differenti diagnosi eventu molecular diagnosi gmh patient diagnosi enabl proper counsel prognosi recurr risk enabl individu patient manag | D054221;D054091 | T047 |
34,666,231 | neonat hypox ischaem encephalopathi motor impair beyond cerebr palsi research investig neuromotor function absenc cerebr palsi cp children neonat hie limit | D002547;D020925;D000068079 | T047;T019 |
34,666,230 | strength measur patient dravet syndrom dravet syndrom ds development epilept encephalopathi character drug resist infantil onset seizur cognit motor impair walk problem progress occur crouch gait frequent observ muscl weak hypothes contribut impair yet far studi perform strength measur patient ds like due cognit impair | D004831;D013036 | T033;T047 |
34,666,229 | autom detect grade invas ductal carcinoma breast cancer use ensembl deep learn model invas ductal carcinoma idc breast cancer signific health concern women around world earli detect diseas may increas surviv rate patient therefor comput aid diagnosi cad base system assist pathologist detect diseas earli studi present ensembl model detect idc use densenet densenet follow test time augment tta model achiev balanc accuraci f score outperform current state art compar analysi various pre train deep learn model preprocess method carri qualit analysi also conduct test dataset detect idc breast cancer import grade treatment studi also propos ensembl model grade idc use pre train densenet densenet resnet v resnet architectur model infer two valid cohort patch level classif model yield overal accuraci one valid cohort second valid cohort magnifi imag respect architectur valid use differ idc dataset achiev overal accuraci perform model detect grade idc show use help pathologist detect grade diseas | D001943;D044584;D018270;D000077321 | T191;T066 |
34,666,227 | distribut social semant infer word mean communic pattern distribut model lexic semant proven power account word mean acquir natur languag environ gnther rinaldi marelli kumar standard model type acquir mean word learn word co occurr statist across larg corpora howev model ignor social communic aspect languag process consid central usag base adapt theori languag tomasello beckner et al john recent demonstr integr social communic inform lexic strength measur allow benchmark fit attain lexic organ data indic social world contain import statist inform languag learn process analysi communic pattern individu onlin forum reddit total approxim billion word text find current articl demonstr social inform word usag allow uniqu aspect word mean acquir provid new pathway distribut model develop | D007802;D012660 | T171;T078 |
34,666,226 | discord humor cell immun respons sar cov vaccin peopl multipl sclerosi anti cd therapi sphingosin phosphat receptor sp modul anti cd therapi impair humor respons sar cov mrna vaccin relat studi assess impact array diseas modifi therapi dmts multipl sclerosi ms cell immun respons sar cov vaccin | D007111;D056724 | T040;T043 |
34,666,224 | immunolog profil develop sens devic detect il copd asthma chronic obstruct pulmonari diseas copd asthma two common obstruct lung diseas affect million worldwid impos enorm burden global healthcar overlap featur share two diseas often make differenti diagnosi difficult achiev lead misdiagnosi patient asthma copd associ chronic inflamm airway perpetu interplay immunolog mediat crucial role play mediat make attract target diseas diagnosi present studi investig immunolog mediat profil patient compar control potenti biomark develop sens platform identifi multiplex analysi common studi immunolog marker il il il il tgf ifn mcp ngal serum show distinct dysregul pattern il show highest potenti differenti diagnosi impedimetr self assembl monolay sam base sensor detect il develop distinguish asthma copd devic show reliabl output high accuraci sensit toward detect il | D018793 | T129;T116 |
34,666,223 | vitro enzymat electrochem monitor glucos metabol product rat primari hepatocyt high permeabl plate situ continu glucos monitor physiolog cultur condit imper understand dynam cell tissu behavior physiolog respons sinc glucos play import role princip sourc biolog energi therefor examin physiolog relev dynam chang glucos level base glucos metabol product aerob cultur rat primari hepatocyt stimul insulin glucagon high permeabl plate maintain oxygen concentr close periport zone liver glucos monitor devic use oxygen independ glucos dehydrogenas modifi singl wall carbon nanotub electrod place close surfac hepatocyt current respons glucos oxid slight decreas addit insulin presenc glucos due acceler glucos uptak hepatocyt wherea signific increas addit glucagon fructos even absenc glucos due convers fructos glucos base gluconeogenesi phenomena might consist relat physiolog behavior hepatocyt periport region present monitor system would use studi glucos homeostasi diabet vitro | D015190 | T060 |
34,666,222 | molecular profil osteosarcoma children adolesc differ age group use next generat sequenc panel osteosarcoma os malign bone tumor peak incid second decad life possibl associ presenc germlin mutat besid clinician point second rarer group patient develop os year old access next generat sequenc ngs strategi genet alter present os blood sampl patient diagnos second decad life custom ngs panel design main alter describ childhood adolesc neoplasm name oncomin childhood cancer research assay occra use os sampl investig present somat variant tp myc cdk rb pdgfra gene harbor observ genet variant myc cnvs frequent tumor patient diagnos year old x p addit patient diagnos second decad life present higher percentag somat germlin variant germlin variant tp rb found patient analyz clinic variabl tumor histopatholog characterist also collect correl molecular find | D056915;D020022;D009154 | T086;T032;T045 |
34,666,221 | impact morpholog paramet urban ventil compact citi case tuscolano bosco district rome air pollut heat stress major concern associ liveabl resili sustain citi direct affect health comfort associ augment morbid mortal increas energi demand build ventil air clean cool nevertheless detriment effect poor air qualiti may part mitig increas urban ventil strategi close relat level urban urban morpholog therefor detail investig impact differ morpholog urban ventil paramount import comput fluid dynam simul wide use last decad investig effect urban morpholog urban ventil howev studi focus ideal build arrang detail investig role real urban morpholog scarc studi investig ventil compact area citi rome itali steadi state reynold averag navier stoke simul perform analyz impact morpholog paramet mp urban ventil result show consider worsen urban ventil increas build densiti reduct mean wind veloc experienc pedestrian level z p correl five mps eg plan area densiti area weight mean build height volum densiti faad area densiti non dimension mean veloc pedestrian level height evalu simpl model obtain use linear regress analysi among select mps build faad area densiti show remark correl non dimension mean veloc z p r correl valuabl tool practition urban design particular first stage plan highlight area potenti vulner poor air condit without run comput expens simul | D000397;D012119 | T080;T039;T069 |
34,666,220 | oper room onlin medic student surgeri educ time covid march associ american medic colleg recommend dismiss medic student clinic set due covid pandem third year fourth year medic student home ms interest teach resid faculti fewer clinic respons due elect surgeri cancel continu access educ creat virtual surgeri elect vse aim broaden student exposur elicit interest general surgeri gs | D020375;D004504;D013337 | T097;T065 |
34,666,217 | trend sequenc initi alcohol tobacco marijuana use among adolesc argentina chile variat drug polici norm substanc use time across countri may affect normat sequenc adolesc substanc use initi estim relat absolut time vari associ prior alcohol tobacco use adolesc marijuana initi argentina chile relat measur quantifi magnitud associ wherea absolut measur quantifi excess risk | D000294;D002188;D000074609;D019966 | T121;T002;T109;T055;T167;T048;T033 |
34,666,211 | intestin ciliat ciliophora wild plain zebra equus quagga south africa note microtubul cytoskeleton organis investig ciliat communiti digest tract differ wild vertebr import context host specif differ ciliat speci detect case non specif infect present descript analysi fauna ciliat litostomatea trichostomatia inhabit intestin wild plain zebra equus quagga boddaert south africa nineteen speci belong genera five famili found five speci specif equus quagga one also found equus zebra common differ equid one previous describ rhinocero first time use immunofluoresc stain investig microtubul cytoskeleton trichostomatid found stain method use identif trichostomatid | D016798;D018397 | T204;T015 |
34,666,210 | scale granul colour sexual dimorph trichoni lepidoptera lycaenida theclina larg fraction dorsal wing surfac ground scale show unusu granul natur compos materi appar extrud scale lumen male individu trichoni hewitson speci tribe eumaeini rare guyanian amazonian genus granul male specimen known femal granul granul scale investig various microscop optic scan transmiss electron microscopi focus ion beam lamella cut spectroscop optic reflect energi dispers x ray ed raman techniqu characterist blue colour uniqu south american repres tribe document analys ed spectra show granul contain addit calcium oxygen compar un granul region scale electron diffract insid tem reveal crystallin compon granul granul wing surfac male exhibit uv absorpt band nm characterist biogen caco therefor materi granul tentat identifi caco shown granul influenc optic properti dorsal wing surfac result characterist spectrum | D002080 | T204 |
34,666,209 | treatment anal fissur result nation survey french practic treatment anal fissur af base medic treatment nonop therapi surgic procedur howev choic treatment role therapeut strategi vari one countri anoth date standard french recommend current avail aim assess french practic treatment af | D005401 | T047 |
34,666,208 | practic guid implement smart asthma manag use singl inhal contain combin inhal corticosteroid ic formoterol specif long act bronchodil mainten quick relief therapi singl mainten reliev therapi smart mart recommend global initi asthma nation asthma educ prevent program coordin committe step asthma manag articl provid practic advic implement smart clinic practic base evid clinic experi fundament smart ic formoterol provid quick relief asthma symptom similar short act agonist albuterol reduc risk sever asthma exacerb overal lower ic exposur smart clinic trial adult adolesc age year use budesonid formoterol g deliv dose one inhal twice daili step two inhal twice daili step step patient take addit inhal budesonid formoterol g one inhal whenev need symptom relief maximum adult adolesc total inhal singl day deliv g formoterol efficaci safeti smart budesonid formoterol beclometason formoterol confirm ic long act bronchodil combin studi smart regimen introduc care explan role self manag prefer custom written asthma action plan cost patient avail smart treatment depend prescrib dose nation local payer agreement | D001249;D019819 | T047;T121;T109 |
34,666,207 | impact function laryngoscopi diagnosi laryng hypersensit syndrom chronic cough vocal cord dysfunct manifest laryng hypersensit syndrom | D055154;D007830;D064706 | T023;T047;T184;T048;T033;T030 |
34,666,205 | heart brain neuromodul vasovag syncop well known autonom nervous system an major contributor etiopathogenesi vasovag syncop vvs cathet base neuromodul cna intrins cardiac an evolv rapid experiment unproven procedur current status increas perform ablat procedur mani major hospit worldwid present review aim bring anatom element intrins cardiac an clinic applic intrins cardiac neuromodul togeth review anatom terminolog clinic data order provid practic assist electrophysiolog communiti | D017115;D019462 | T047;T061 |
34,666,204 | effect femal male friendship male postcopulatori level oxytocin vasopressin sperm paramet macacaarctoid male femal stump tail macaqu macaca arctoid form close relationship akin human friendship oxytocin vasopressin modul social relationship reproduct behavior physiolog various mammal speci besid behavior effect oxytocin hormon play essenti role ejaculatori process favor sperm transport upward femal reproduct tract therefor investig influenc friendship postcopulatori serum level oxytocin vasopressin stump tail macaqu macaca arctoid addit search correl kind social relationship sperm transport vagina periovulatori luteal phase six femal six male adult macaqu differ friendship indic serv experiment anim alloc mate pair combin anim allow copul luteal periovulatori phase blood sampl collect anim finish copul measur oxytocin vasopressin afterward profound sedat femal collect three semen sampl vagina everi min perform spermatobioscopi male post copul oxytocin valu increas along friendship index vasopressin behav opposit sperm concentr immotil motil sperm decreas one sampl anoth male femal close increas final periovulatori phase first vagin sampl sperm veloc signific increas friendship indic result show stump tail macaqu heterosexu friendship promot higher postcopulatori oxytocin concentr better physiolog condit male probabl enhanc reproduct success | D033062;D010121 | T116;T121;T098;T125;T054 |
34,666,203 | profeel open sourc dosimetri data visual analysi softwar articl present profeel matlab mathwork inc base open sourc dosimetri data visual analysi softwar profeel aim support qualiti assur dosimetri research field radiotherapi provid environ visual process analys measur simul dosimetri data sever data sourc use radiotherapi practic research | D000078326;D012984 | T170;T073;T090 |
34,666,202 | two untarget metabolom reveal yogurt associ metabol alter women multipl metabol disord random control studi benefici role yogurt metabol profil wide report yet studi intend describ integr metabol alter respons yogurt yogurt milk gd given obes women metabol syndrom nonalcohol fatti liver diseas week random control trial regist http wwwchictrorgcn chictr ipr fast serum sampl collect intervent global untarget metabolom base h nuclear magnet reson nmr ultra high perform liquid chromatographi coupl electrospray ionize time flight mass spectrometri uplc q tof ms posit negat ion mode multivari statist analysi pathway analysi conduct h nmr uplc q tof ms metabolom cluster observ two group baselin clear cluster shown intervent yogurt group signific differ metabol status milk metabolit contribut most class separ identifi involv pathway analysi pathway amino acid metabol fatti acid oxid cholesterol catabol cholin metabol signific chang yogurt intervent studi reveal integr metabol alter respons yogurt via two metabolom approach suggest potenti mechan yogurt metabol disord trial registr chines clinic trial registri chictr ipr regist juli http wwwchictrorgcn chictr ipr signific review prospect studi random clinic trial show protect role yogurt multipl metabol disord howev focus target glucos lipid metabol indic part human metabol fail show integr metabol featur yogurt therefor two global untarget metabolom appli current random clinic trial tri uncov signific metabol alter character effect yogurt obes women multipl metabol disord explor potenti biolog mechan yogurt find shed light comprehens pictur yogurt affect host metabol provid theoret foundat dietari prevent chronic diseas | D024821;D015014 | T047;T168 |
34,666,201 | impact magnesium bone health older adult systemat review meta analysi magnesium play key role bone health may therefor repres interest nutrient prevent bone loss osteoporosi aim systemat review meta analysi investig impact magnesium intak sourc bone miner densiti bmd bone miner content bmc bone turnov marker fractur risk older adult | D008274;D010024 | T047;T196;T123 |
34,666,200 | earli impair cartilag poroelast properti anim model acl tear case anterior cruciat ligament acl lesion lead post traumat osteoarthr ligament reconstruct stabil joint tear seem impair poroelast cartilag synovi membran fluid inflamm observ week tear descript visibl cartilag chang poroelast never analyz earli stage present anim studi aim determin whether cartilag show earli poroelast deterior acl tear whether impair correl macroscop chang whether cartilag poroelast deterior time | D000070598;D059549;D002358 | T061;T024;T037 |
34,666,198 | interimpl femor fractur number hip knee arthroplasti intern fixat proxim distal femur increas proport grow age popul whose life expect lengthen thus fractur femur proxim distal implant although rare becom frequent women age fragil bone whose end two implant close kiss implant particular vulner reliabl reproduc fractur classif exist come prosthes less well establish presenc one even two non prosthet implant treatment difficult must consid possibl fractur consolid ensur restor stabil role implant whether main element treatment complement prosthesi revis lock plate form basi treatment must rigor consid failur main result technic error invas treatment total femor arthroplasti cortic sleev offer rare consolid appear compromis | D019644;D019645;D005264;D057068 | T037;T047;T061 |
34,666,197 | quantit activ level gestat age deliveri prospect cohort studi among nullipar women despit knowledg bed rest reduc risk preterm birth ptb continu recommend mani provid worldwid quantit data assess relationship ptb physic activ pregnanc design prospect cohort studi use fitbit activ tracker quantit explor associ baselin physic activ pregnanc stepsday risk ptb week | D047928 | T046 |
34,666,196 | efficaci antimicrobi photodynam therapi er cr ysgg laser activ irrig dentin tubul penetr mta base root canal sealer confoc microscopi studi antimicrobi photodynam therapi apdt laser activ irrig lai adjunct therapi develop enhanc effect root canal disinfect sealer penetr dentin tubul signific prevent infect sealer penetr abil affect chemo mechan prepar root canal studi aim evalu efficaci apdt lai dentin tubul penetr mta base root canal sealer | D053844;D010778;D012387 | T061;T074;T122;T073 |
34,666,195 | robot assist nippl spare mastectomi follow immedi microsurg free flap reconstruct feasibl aesthet result case seri applic robot assist nippl spare mastectomi r nsm allow mastectomi perform via small incis breast reconstruct free autolog tissu result natur long last result howev applic r nsm difficult via small incis nt explor depth purpos studi investig feasibl aesthet outcom free perfor flap breast reconstruct via small later chest wall incis r nsm | D001943;D058752;D016462;D065287 | T191;T024;T061 |
34,666,194 | quantit character human retinotop map base quasiconform map retinotop map depict cortic neuron respons visual stimuli retina contribut signific understand human visual system although recent advanc high field function magnet reson imag fmri made possibl generat vivo retinotop map great detail quantifi map remain challeng exist quantif method preserv surfac topolog often introduc larg geometr distort map studi develop new framework base comput conform geometri quasiconform teichmller theori quantifi retinotop map specif introduc general pipelin consist cortic surfac conform parameter surfac spline base cortic activ signal smooth vertex wise beltrami coeffici base map descript correct violat topolog condit result beltrami coeffici map bcm rigor complet character retinotop map quantifi local quasiconform map distort visual field locat bcm provid topolog fulli reconstruct retinotop map success appli new framework analyz v retinotop map human connectom project n largest state art retinotopi dataset current avail unpreced precis found v retinotop map quasiconform local map distort similar across observ new framework appli visual area retinotop map individu without eye diseas improv understand visual cortic organ normal clinic popul | D063132;D014793 | T091;T017;T023;T029 |
34,666,191 | deeps detect super enhanc among typic enhanc use sequenc featur embed super enhanc se cluster activ typic enhanc te high level mediat complex master transcript factor chromatin regul ses play key role control cell ident diseas tradit scientist use varieti high throughput data differ transcript factor chromatin mark distinguish ses tes kind experiment method usual cost time consum paper propos model deeps base deep convolut neural network model distinguish ses tes deeps repres dna sequenc use dnavec featur embed dna sequenc inform deeps outperform state art method addit deeps general well across differ cell line impli cell type specif ses may share hidden sequenc pattern across differ cell line sourc code data store github https githubcomqiaoyingjideeps | D002843;D004742 | T116;T114;T123 |
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