PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,662,899 | cognit psycholog function chiari malform type surgic decompress prospect cohort studi chiari malform type cm defin cerebellar tonsil displac mm foramen magnum displac alter cerebrospin fluid flow cervicomedullari junction result valsalva induc headach syringomyelia compress brainstem result bulbar symptom howev littl known cognit psycholog chang cm | D001139;D013595 | T047;T019 |
34,662,898 | role surgic resect multifoc glioblastoma retrospect analysi patient glioblastoma multipl local mgbms defin multifoc enhanc lesion present connect visibl magnet reson imag fluid attenu invers recoveri imag multicentr absenc clear dissemin pathway | D001932;D005909 | T191 |
34,662,896 | mrd stratifi pediatr protocol deliver adolesc young adult children pediatr regimen improv outcom adolesc young adult aya acut lymphoblast leukemia howev result remain inferior children australasian leukaemia lymphoma group allg studi anzctrorgauactrn design assess whether pediatr regimen australian new zealand children haematolog oncolog group anzchog studi could administ patient age year compar time frame children assess proport patient complet inductionconsolid commenc next phase therapi protocol high risk hr treatment day minim residu diseas mrd respons stratifi patient hr treatment transplant total patient enrol elig median age year rang year inductionconsolid equal deliver studi confid interv ci commenc protocol hr therapi day vs studi p median time protocol mhr treatment day interquartil rang day vs day studi p induct mortal median follow month month estim year diseas free surviv ci estim year overal surviv ci end inductionconsolid mrd negat rate bodi mass index kgm day mrd posit associ poorer diseas free surviv overal surviv pediatr therapi safe deliver aya patient children intoler pediatr inductionconsolid major contributor inferior outcom aya | D054198 | T191 |
34,662,895 | evolv frontlin immunochemotherapi mantl cell lymphoma impact surviv outcom dvanc frontlin treatment mantl cell lymphoma mcl last decad sought character chang frontlin treatment pattern associ outcom patient newli diagnos mcl septemb june enrol prospect cohort studi clinic characterist treatment clinic outcom compar patient diagnos era compar era patient age sex simplifi mcl intern prognost index smipi score similar group patient age year younger less use rituximab plus hyperfraction cyclophosphamid vincristin doxorubicin dexamethason r hyper cvad vs use rituximab plus maximum strength cyclophosphamid doxorubicin vincristin prednison r maxi chop altern rituximab plus high dose cytarabin r hidac also known nordic regimen r chop altern rituximab plus dexamethason high dose cytarabin cisplatin r dhap vs less use r chop r chop like regimen vs use r bendamustin vs era p chang associ improv event free surviv ef year ef vs p overal surviv os year os vs p era patient older age year less use r chop r chop like therapi vs nonstandard system therapi vs use r bendamustin vs chang associ trend improv ef year ef vs p era shift r chop r chop like regimen r bendamustin associ improv ef year ef vs p era result prospect cohort studi provid critic real world evid improv outcom evolv frontlin pattern care patient mcl | D020522 | T191;T047 |
34,662,893 | bilater nervus intermedius section genicul neuralgia case report oper video genicul neuralgia rare condit character excruci ear pain surgic option genicul neuralgia includ microvascular decompress section nervus intermedius report herein case bilater genicul neuralgia treat nervus intermedius section without prior microvascular decompress knowledg first report treatment strategi subsequ descript side effect bilater nervus intermedius disrupt | D020773;D016697;D061145 | T047;T061 |
34,662,892 | anticoagul cancer associ thromboembol thrombocytopenia prospect multicent cohort studi venous thromboembol vte concurr thrombocytopenia frequent encount patient cancer therapeut anticoagul set thrombocytopenia associ high risk hemorrhag retrospect analys suggest util modifi dose anticoagul popul assess incid hemorrhag thrombosi accord anticoagul strategi perform prospect multicent observ studi patient activ malign acut vte concurr thrombocytopenia platelet count l enrol cumul incid hemorrhag recurr vte determin consid death compet risk primari outcom central adjud comparison made accord initi treatment full dose modifi dose anticoagul total patient enrol hospit seventi five patient initi treat full dose anticoagul modifi dose anticoagul patient receiv anticoagul patient receiv modifi dose anticoagul hematolog malign acut deep vein thrombosi patient initi receiv full dose anticoagul cumul incid major hemorrhag day confid interv ci ci receiv modifi dose anticoagul fine gray hazard ratio ci cumul incid recurr vte day patient initi receiv full dose anticoagul ci patient receiv modifi dose anticoagul conclus modifi dose anticoagul appear safe altern therapeut anticoagul patient cancer develop deep vein thrombosi set thrombocytopenia | D013921;D054556 | T047 |
34,662,891 | vpreb surrog light chain express b lineag report children oncolog group immunotherapi direct b cell surfac marker common development strategi treat b cell malign immunoglobulin heavi chain surrog light chain slc compris vpreb cda lamda cdb subunit express pro pre b cell govern pre b cell receptor bcr mediat autonom surviv signal hypothes pre bcr might merit develop target immunotherapi decoupl autonom signal b lineag acut lymphoblast leukemia b use children oncolog group cog minim residu diseas mrd flow panel assess pre bcr express primari patient sampl accru cog standard high risk b studi aallb also assess cda express case day end induct sampl preselect mrd analys perform color becton dickinson flow cytomet clinic laboratori improv amendmentcolleg american pathologist certifi laboratori among case test case pre b case pro b stage development arrest one monoclon antibodi mab show cda present b lymphoblast popul case express cda end induct b lymphoblast popul cda compon slc common express b regardless genotyp stage development arrest nation cancer institut risk status | D002051;D016393;D054198 | T191 |
34,662,890 | apixaban compar warfarin prevent thrombosi thrombot antiphospholipid syndrom random trial thrombot antiphospholipid syndrom tap character venous arteri microvascular thrombosi patient tap merit indefinit anticoagul warfarin histor standard treatment apixaban oral factor xa inhibitor anticoagul requir dose adjust monitor efficaci safeti apixaban compar warfarin tap patient remain unknown multicent prospect random open label blind endpoint studi assign anticoagul tap patient apixaban warfarin target intern normal ratio month primari efficaci outcom clinic overt thrombosi vascular death apixaban first given mg twice daili two protocol chang institut base recommend data safeti monitor board twenti fifth patient random apixaban dose increas mg twice daili thirtieth patient random subject prior arteri thrombosi exclud primari outcom adjud independ expert blind treatment alloc patient random februari march apixaban n warfarin n similar among compon primari efficaci outcom stroke occur patient random apixaban compar patient random warfarin studi end prematur forti eighth patient enrol conclus studi limit due protocol modif low patient accrual despit limit result suggest apixaban may routin substitut warfarin prevent recurr thrombosi especi stroke among patient tap trial regist wwwclinicaltrialsgov nct | D016736;D020521;D013927 | T047;T046 |
34,662,889 | oper treatment sever scoliosi symptomat adult multicent assess outcom complic minimum year follow report focus adult sever scoliosi | D012600;D013123 | T047;T061 |
34,662,888 | socioeconom sex area relat inequ childhood stunt mauritania evid mauritania multipl indic cluster survey preval stunt five children high mauritania howev pauciti evid extent overtim alter inequ stunt end studi investig stunt inequ chang time use three round mauritania multipl indic cluster survey evid import inform implement equit nutrit intervent help narrow inequ stunt popul group | D006130 | T046 |
34,662,886 | exom sequenc analysi uk biobank particip major goal human genet use natur variat understand phenotyp consequ alter protein code gene genom use exom sequenc explor protein alter variant consequ particip uk biobank studi identifi million code variant includ around million loss function around million deleteri missens variant test associ health relat trait found gene trait associ p rare variant associ enrich loci genom wide associ studi gwas independ common variant signal discov sever risk increas associ trait relat liver diseas eye diseas cancer among other well risk lower associ hypertens slcar diabet mapk fama asthma slca six gene associ brain imag phenotyp includ two involv neural develop gbe pld signal avail power replic independ cohort confirm furthermor associ signal general consist across individu european asian african ancestri illustr abil exom sequenc identifi gene trait associ elucid gene function pinpoint effector gene underli gwas signal scale | D018070;D030541;D000073359 | T170;T093;T063 |
34,662,885 | proinflammatori cytokin profil differ primari open angl pseudoexfoli glaucoma studi investig glaucoma biomark aqueous humor tear found elev proinflammatori cytokin patient primari open angl glaucoma poag pseudoexfoli glaucoma pxg studi investig differ inflammatori cytokin poag pxg patient find specif diseas biomark | D016207;D005901;D005902 | T129;T047;T116 |
34,662,884 | covid pandem health crisi manag panic respons disastr futur consequ year covid spread rapid worldwid affect societi age group taken toll human live approach million peopl infect million report death time write also decim everi economi countri struggl control infect rate introduc draconian lockdown social distanc measur bring great suffer well beyond medic effect diseas parallel pandem result delug inform eman scientif well intern news media includ social media platform fact fiction realiti percept becom entangl realist solut medic well polit concert global vaccin current underway reduc infect introduc univers immun howev public controversi rage due widespread apprehens regard necess immedi risk long term safeti perceiv fast track medic concern may justifi much due misconcept misunderstand review highlight issu concern handl covid crisi govern worldwid medic scientif communiti media may laid foundat far greater medic social econom burden come year present compar data challeng current concept diseas general context human health provid perspect seem lost general panic need ration approach handl diseas unlik disappear spectrum afflict even magnifi glass remov | D000086382;D003140;D061108 | T058;T047;T170;T067 |
34,662,882 | influenza pandem back futur centuri sinc flu pandem sometim refer mother pandem brief retrospect pandem taken viewpoint current sar cov covid pandem base short lectur given virtual congress era edta | D000086382;D058873 | T047;T067 |
34,662,881 | solubl endoglin uterin arteri flow doppler ultrasonographi marker progress preeclampsia women gestat hypertens gestat hypertens gh pregnanc high risk develop advers outcom includ progress preeclampsia predict gh relat advers outcom challeng avail clinic test may predict occurr | D046110;D011225 | T047;T046 |
34,662,880 | identifi amygdala like territori scyliorhinus canicula chondrichthyan evid pallial amygdala identifi putat amygdalar complex cartilagin fish first step obtain evid support exist pallial amygdala catshark scyliorhinus canicula present prevail chondrichthyan model compar neurobiolog development biolog end analyz organ later wall telencephal hemispher adult juvenil earli prehatch embryo immunohistochemistri tyrosin hydroxylas th somatostatin som pax serotonin ht substanc p sp met enkephalin metenk calbindin k cb calretinin cr situ hybrid regulatori gene tbr lhx emx dlx data integr avail literatur relat secondari olfactori project shark speci character two possibl amygdalar territori one may repres ventropalli compon identifi chemic signatur moder densiti pax ir cell scarc th ir som ir cell absenc cr ir cb ir cell gene express tbr lhx express emx negat domain ventral pallium amniot perhap compar later amygdala amphibian pallial amygdala teleost second territori relat pallial subpalli boundari abund pax ir cr ir cell ht ir sp ir metenk ir fiber cap dorsal area superficiali basali olfactori relat region neighborhood pallial subpalli boundari may repres subpalli amygdala subdivis possibl contain migrat cell ventropalli origin | D000679;D013687 | T023 |
34,662,879 | ideal helicobact pylori treatment present futur helicobact pylori erad treatment wide perform improv gastric mucos inflamm promot ulcer heal reduc incid gastric cancer howev sever issu associ h pylori erad treatment first various treatment regimen current use worldwid standard treatment vari region countri second antimicrobi resist h pylori increas due indiscrimin antibiot use final gut microbiota dysbiosi potenti induc h pylori treatment | D016481;D016480 | T007;T047 |
34,662,878 | prolong ventricular paus atrial fibril marker poor prognosi patient atrial fibril af long term prognosi long electrocardiograph paus ventricular action well studi | D001281;D010138 | T074;T047;T046 |
34,662,877 | growth hormon stimul test pattern contribut sex differ pediatr growth hormon treatment male twice like femal receiv pediatr growth hormon gh treatment usa despit similar distribut height z htz score sex male predomin evalu subspecialti referr short statur contribut observ studi investig whether sex differ gh stimul test subsequ gh prescript contribut male predomin gh treatment | D019382;D012727 | T032;T116;T121;T125 |
34,662,875 | ultra perform liquid chromatographi q exact orbitrap mass spectrometri analysi metabol communic heart kidney adriamycin induc nephropathi rat although adriamycin induc nephropathi model frequent employ studi nephrot syndrom focal segment glomerulosclerosi accompani myocardi damag alway caus concern therefor great need studi cardioren communic model | D053858 | T044;T169 |
34,662,874 | dynam patholog dataset creation use urin cytolog exampl dataset creation one first task requir train ai algorithm underestim patholog high qualiti data essenti train algorithm data label accur includ suffici morpholog divers dynam challeng label urin cytolog dataset use pari system tps criteria present | D014571 | T191 |
34,662,872 | clinic molecular epidemiolog crimean congo hemorrhag fever human uganda crimean congo hemorrhag fever cchf endem uganda yet epidemiolog remain larg uncharacter better understand occurr within uganda case report patient hospit cchf review genom sequenc cchf posit rna obtain period determin phylogenet comparison found total case male cfr age year report studi period case detect juli decemb outbreak year p locat along cattl corridor p common present symptom fever hemorrhag headach fatigu vomit myalgia five patient hematolog data avail vari abnorm observ includ thrombocytopenia leukopenia anemia lymphopenia lymphocytosi polycythemia microcytosi p patient report tick bite exposur livestock potenti sourc infect person person transmiss suspect two case use unbias metagenom found viral l segment remain conserv africa clade sinc contrast segment split two geograph interspers clade one belong africa anoth ancestr africa overal data summar inform histori clinic present human cchf uganda import identifi vulner popul well tempor geograph region uganda surveil control intervent could focus | D006479 | T047 |
34,662,871 | case report rapid respons low dose thalidomid case sever steroid recalcitr erythema nodosum leprosum erythema nodosum leprosum enl type lepra reaction present crop evanesc tender erythemat nodul accompani fever arthralgia malais organ specif manifest seen borderlin lepromat leprosi drug approv enl includ nonsteroid anti inflammatori drug system steroid thalidomid clofazimin manag enl challeng long term steroid use lead steroid depend present patient sever steroid recalcitr enl vesicular pustular lesion mimick sweet syndrom treat effect low dose thalidomid regimen mgd oppos high dose mgd recommend literatur discuss patho mechan clinic util low dose thalidomid regimen effect treatment option enl | D013792 | T131;T121;T109 |
34,662,870 | assess commerci real time pcr assay detect malaria infect non endem set malaria control elimin requir prompt diagnosi accur treatment convent method rapid diagnost test rdts microscopi lack characterist detect low parasitemia common found asymptomat parasitemia andor submicroscop malaria carrier contrari molecular method higher sensit specif studi evalu perform two commerci real time polymeras chain reaction pcr assay realstar malaria pcr realstar genus realstar malaria screen type pcr realstar speci compar refer nest multiplex malaria pcr detect main five plasmodium speci affect human total sampl evalu valu sensit specif realstar genus realstar speci assay respect good limit detect lod realstar genus assay show mean valu parasitesl plasmodium falciparum sampl lod realstar speci assay rang parasitesl p vivax two parasitesl p oval time complet diagnosi establish hour find show good concord assay compar refer method good analyt sensit realstar speci assay abl correct character doubl tripl infect therefor realstar assay shown use tool malaria diagnosi non endem countri even endem countri malaria control general detect low parasitemia sensit similar sensit method nest pcr lower time get result | D060888 | T063 |
34,662,869 | global crowdsourc open call improv research mentorship low middl incom countri mix method analysi research mentor program limit mani low middl incom countri lmic tdr global initi global crowdsourc open call solicit propos improv research mentorship lmic purpos studi examin idea submit open call identifi way improv research mentorship lmic open call group individu solv part problem share solut whotdrsesh crowdsourc guid use structur open call submiss judg three independ individu scale textual submiss extract elig propos qualit analyz via induct deduct code techniqu identifi theme open call receiv submiss countri asia africa latin america europ among particip research experi total submiss receiv mean score higher themat analysi identifi three overarch theme relat prementor facilit evalu prementor establish mentor mente compat lay foundat mentorship facilit involv iter cycl plan communic skill improv evalu creat commit account within framework monitor global crowdsourc open call generat numer mentorship idea includ lmic contextu facilit tool open call demonstr need greater focus mentorship data may inform develop formal inform mentor program lmic set | D063045;D014943;D008611;D064890 | T065;T098;T170;T091;T067;T078;T033;T062 |
34,662,868 | resid time water contact age driven schistosoma mansoni infect hotspot communiti uganda schistosomiasi second import parasit infect malaria term socioeconom impact endem countri affect million peopl worldwid case occur sub saharan africa uganda schistosoma mansoni common speci seven million peopl infect million live risk despit mass drug administr mda praziquantel initi year ago shift schistosomiasi goal control morbid elimin public health problem understand driver infect persist transmiss hotspot despit ongo control intervent paramount conduct cross section epidemiolog studi individu bugoto communiti mayug district eastern uganda along structur survey ascertain driver mansoni infect bugoto communiti wide mda sinc detect mansoni preval across whole communiti preval school age children qualifi bugoto high endem communiti accord guidelin use multivari logist regress found mansoni infect best explain age group longer resid time daili contact lake water schistosoma mansoni infect remain larg burden across communiti studi identifi opportun intervent reduc lake water contact expand treatment elig risk improv mda coverag long term resid set control schistosomiasi persist transmiss hotspot | D012111 | T082;T056;T083;T078;T081;T033;T096 |
34,662,867 | nutrit inflamm gut microbiota among outpati activ tuberculosi diseas india india highest rate tuberculosi tb global high preval malnutrit howev interplay host nutrit status inflamm gut microbiom activ tuberculosi diseas atbd less well studi examin differ gut microbi composit divers base undernutrit inflamm status among outpati atbd time treatment initi exploratori cross section studi outpati n atbd confirm xpert mtbrif enrol anti tb treatment initi hospit rural southern india rrna sequenc use assess composit gut microbiom assess multipl marker nutrit status includ micronutri status concentr vitamin oh vitamin b ferritin anthropometri bodi mass index mid upper arm circumfer height c reactiv protein crp indic inflamm found oh posit associ relat abund oscillospira spp butyr produc genus link anti inflamm effect ferritin posit associ proteobacteria taxa associ wors inflamm studi final found greater abund inflamm associ taxa proteobacteria phylum lower alpha divers indic among underweight low mid upper arm circumfer short statur summari found differ gut microbiota composit divers among undernutrit compar adequ nutrit status time initi treatment among patient atbd india clinic implic find need examin larger longitudin studi | D000069196;D009752 | T033;T007;T001 |
34,662,866 | caus outcom admiss investig tuberculosi adult advanc hiv south african hospit data tb fast track trial tuberculosi tb remain lead caus hospit hospit mortal hiv posit adult use data hospit clinic file research databas autopsi describ caus outcom admiss assess investig tb among adult advanc hiv hospit enrol tb fast track trial south africa total adult median cd count cellsl interquartil rang cellsl antiretrovir therapi experienc admiss nineti five first admiss tb relat next common caus aid relat ill surgic caus admit previous undiagnos tb cd count less cellsl overal individu die inpati within day first discharg case fatal rate particular high admit tb bacteri infect admiss anti tb treatment start admiss sputum base tb investig record admiss one tb symptom record start treatment admiss tb symptom record start treatment hospit adult advanc hiv high risk death tb common caus hospit investig even symptom addit earli identif tb aid relat ill hospit adult advanc hiv improv pre hospit manag strategi need interrupt diseas progress reduc poor outcom alreadi vulner popul | D017052 | T080 |
34,662,864 | model impact season malaria chemoprevent district level suspect confirm malaria case chad base routin clinic data sulfadoxin pyrimethamin plus amodiaquin deliv children age month season malaria chemoprevent smc area transmiss high season chad sahelian countri although clinic trial show reduct malaria case evid smc impact scale remain limit use data chadian nation health manag inform system analyz associ smc implement juli octob month district level malaria incid suspect confirm outpati case among children age month health facil health district smc implement general addit model fit separ cyclic cubic spline term district adjust season case smc implement chad associ compar implement lower month count suspect rate ratio rr ci p confirm malaria case rr ci p repres around reduct malaria incid sensit analys show effect size modifi model assumpt caution exercis interpret find may compar studi may underestim impact smc malaria case present health facil suspect case test facil report case consist studi approach present solut employ readili avail routin data evalu impact health intervent scale without extens covari data effort need improv qualiti routin data chad elsewher | D012621 | T079 |
34,662,863 | case report first borrelia yangtzensi infect human korea borrelia yangtzensi identifi rodent tick china japan year old woman bite mark diagnos b yangtzensi infect via molecular serolog test report first case human infect caus b yangtzensi korea | D001898 | T007 |
34,662,859 | effect host avail fit aed albopictus blood feed pattern new york aed albopictus compet vector numer pathogen repres rang transmiss cycl involv uniqu host despit import status vector variat feed pattern poor understood examin feed pattern ae albopictus util rest collect long island ny contextu blood meal sourc host avail measur household interview camera trap identifi blood meal includ human cat hors opossum dog goat rabbit rat squirrel raccoon third studi ae albopictus blood feed biolog quantit assess domest host avail first wild anim host feed indic show cat dog fed upon disproportion often compar human forag ratio suggest tendenc feed cat opossum avoid raccoon squirrel bird feed pattern differ anoth publish studi baltimor ae albopictus fed often rat human understand whether differ host avail mosquito popul variat compar fit new york baltimor ae albopictus feed rat human blood addit examin fit within new york popul feed human rat cat hors opossum blood togeth result indic major mosquito fit differ blood host suggest fit benefit drive northeastern ae albopictus feed pattern | D006790 | T070 |
34,662,858 | proxim resid irrig determin malaria risk anophel abund irrig agroecosystem malawi countri sub saharan africa expand irrig improv food secur foster econom growth import quantifi malaria risk associ process irrig ecosystem associ increas malaria risk relationship fulli understood studi relationship bwanj valley irrig scheme hectar malawi household preval malaria indoor anophel densiti quantifi two cross section studi resid household multilevel logist regress use estim associ distanc irrig scheme malaria infect mosquito densiti preval malaria infect histidin rich protein base malaria rapid diagnost test microscopi individu resid household within km scheme signific higher preval infect adjust odd ratio aor confid interv ci school age children highest preval among age group aor ci individu report bed net use household higher socioeconom status higher level educ household head spous lower odd malaria infect femal anophel mosquito total anophel arabiensi anophel funestus signific abund hous locat within km scheme proxim human dwell irrig scheme increas malaria risk higher household wealth index reduc risk therefor multisector approach spur econom growth mitig increas malaria transmiss need peopl live close irrig site | D057914;D012111 | T082;T056;T083;T081;T068;T078;T033;T096 |
34,662,857 | lower global lung ultrasound score associ higher likelihood success extub invas ventil covid patient lung ultrasound lus use assess loss aerat associ outcom patient coronavirus diseas covid present emerg depart hypothes lus score associ outcom critic ill covid patient receiv invas ventil retrospect intern multicent studi evalu patient covid relat acut respiratori distress syndrom ard least one lus studi within day invas mechan ventil initi global lus score calcul sum region score rang pleural line abnorm subpleur consolid also score outcom success liber ventil intens care mortal within day analyz multist compet risk proport hazard model one hundr thirti seven patient covid relat ard includ studi global lus score associ success liber mechan ventil hazard ratio hr confid interv ci p independ ard sever day mortal hr ci p subpleur consolid pleural line abnorm add prognost valu global lus score examin within hour intub show prognost valu conclud lower global lus score hour invas ventil initi associ increas probabl liber mechan ventil covid ard patient independ ard sever | D060666;D000086402;D014463 | T005;T061;T060 |
34,662,856 | leisur time physic activ glycem control independ predict cardiac autonom neuropathi type diabet mellitus though cardiac autonom neuropathi common complic type diabet mellitus tdm still lack clariti pathophysiolog correl onset progress therefor purpos studi investig predict abil lifestyl cardiometabol risk factor tdm patient | D003924 | T047 |
34,662,855 | physic activ stool metabolit relationship among adult high risk colorect cancer adenomat polyp associ increas risk develop colorect cancer physic activ pa spend less time sedentari may reduc risk polyp recurr cancer incid studi examin associ pa sedentari time stool metabolit adult high risk develop colorect cancer | D015179;D015444 | T061;T191;T056 |
34,662,854 | impact outdoor gym adult particip physic activ natur experi chile although low level physic activ slight decreas global need revers physic inact remain urgent one approach instal outdoor gym og | D015444;D012111 | T082;T056;T083;T081;T061;T078;T033;T096 |
34,662,852 | gill physiolog transcriptom respons threaten freshwat mussel solenaia oleivora salin shift solenaia oleivora freshwat shellfish endem china becom one threaten freshwat mussel owe water pollut habitat fragment overfish henc explor respons differ environment factor import conserv work investig physiolog transcriptom respons oleivora increas salin found increas salin caus death oleivora high salin caus shrink deform gill filament reduc gill cilia induc cell apoptosi gill activ superoxid dismutas sod catalas cat acid phosphatas acp alkalin phosphatas akp well glutathion gsh content increas begin salin stress h sod acp activ decreas h transcriptom data reveal high salin stress h induc differenti express gene deg among deg major stress respons ion transport relat gene regul immun relat gene regul conclus find suggest antioxid immun function oleivora inhibit high salin may one main reason low surviv rate condit increas salin | D049872;D005880 | T204;T023 |
34,662,851 | antibiot resist pattern escherichia coli isol clinic wastewat pathway antimicrobi resist amr remain one lead global health threat studi compar antimicrobi resist pattern among e coli isol clinic uropathogen escherichia coli upec hospit wastewat popul throughout urban wastewat treatment facil influent pre post chlorin effluent antibiot suscept isol analyz eleven differ antibiot presenc twelv antibiot resist gene type integras identifi amr exhibit follow pattern upec hospit wastewat urban post chlorin effluent pre chlorin effluent urban influent wastewat howev multi drug resist three antimicrobi class preval among hospit wastewat popul compar sourc e coli wastewat disinfect chlorin signific correl increas trimethoprim sulfamethoxazol resist e coli compar raw treat wastewat popul bla ctx group common extend spectrum beta lactamas e coli hospit wastewat although upec strain also encod bla ctx group bla tem gene among tetracyclin resist popul teta tetb resist gene identifi throughout wastewat popul associ increas phenotyp resist character e coli popul identifi phylogroup b predomin among clinic upec popul correl highest amr wherea elev rate multi drug resist among hospit wastewat most phylogroup togeth find highlight hospit wastewat rich sourc amr multi drug resist bacteri popul | D004926;D004927 | T007;T047 |
34,662,850 | effect curcuma adjunct therapi periodont diseas systemat review meta analysi periodont diseas pd second preval buccal infecti condit adult owe multifactori etiolog treatment mainten challeng scale root plane associ adequ plaqu control consid gold standard treatment diseas howev instrument techniqu fail complet elimin calculus particular higher grade progress rate pd case continu effici remov biofilm patient limit long term respons treatment anti infect herbal product curcuma ad adjuv therapi prolong periodont treatment outcom | D055113;D010510 | T047 |
34,662,848 | impact subcutan viscer fat adipos patient colorect cancer although differ bodi composit includ fat adipos known associ surviv patient colorect cancer crc clinic signific inconsist investig prognost impact viscer subcutan fat adipos patient crc surgic resect | D050154 | T032 |
34,662,847 | consum illicit opioid drug overdos epidem illicit fentanyl drug discern radic transform illicit opioid market north america continu face opioid overdos epidem driven persist increas illicit fentanyl fluctuat potenc lead uncertainti consum qualit studi conduct better understand peopl inject drug pwid came recogn fentanyl grow adulter heroin subsequ sensori discern strategi employ continu inject main object investig observ knowledg combin homegrown techniqu detect fentanyl minim risk secondari object examin impact grow fentanyl adulter individu drug use behavior | D062787;D013287 | T131;T037;T109 |
34,662,846 | infect incid manag multipl sclerosi patient initi diseas modifi therapi diseas modifi therapi multipl sclerosi ms effect frequent cost year predispos patient serious infect retrospect cohort analysi n compar rate infect month period ms medic rout administr antimicrobi use infect rate oral infus inject infect antimicrobi prescrib oral infus inject case found differ within bacteri herp zoster infect rate antimicrobi use among new user medic rout administr find suggest pharmacovigil may inform share decis process choos ms medic | D006562;D009103 | T047 |
34,662,844 | transcutan auricular vagus nerv stimul heart rate variabl analysi paramet target transcutan auricular vagus nerv stimul tavn modul central peripher neurophysiolog specif tavn increas heart rate variabl hrv indic shift autonom function toward parasympathet predomin howev knowledg influenc stimul paramet target scarc hypothes locat charg per phase tavn influenc hrv | D004561;D055536 | T061 |
34,662,842 | breastfeed practic australian tertiari care hospit retrospect studi world health organ recommend infant exclus breastf six month age babi friend health initi bfhi develop protect promot support breastfeed bfhi global criteria guid hospit practic support infant feed reduc dispar breastfeed outcom | D001942;D009035 | T092;T099;T055;T058;T040 |
34,662,841 | parent econom insecur child health explor effect parent econom insecur children hyperact anxieti central argument even control current famili incom employ status parent may legitim feel econom insecur may detriment children data nation longitudin survey children youth indic health year old children wors parent report worri enough money support famili particular boy hyperact girl anxious parent feel less econom secur chang parent style appear channel parent econom insecur affect children | D000067576;D016487 | T058;T054;T078 |
34,662,840 | assess thaw sperm qualiti felin speci ocelot leopardus pardali oncilla leopardus gutullus studi aim evalu cryopreserv effect semen oncilla leopardus guttulus n ejacul ocelot leopardus pardali n ejacul compar two extend commerci non commerci extend androlog exam conduct testicl measur peni evalu includ semen collect electroejacul collect semen assess volum color ph sperm motil vigor sperm number ejacul viabil membran integr sperm morpholog sampl centrifug g min pellet dilut two extend trisglucoseegg yolk botucrio pack ml french straw spermatozoaml equilibr c h cmin freez nitrogen vapor min thaw achiev c min thaw sampl evalu characterist ultrastructur analysi differ extend ocelot spermatozoa maintain higher qualiti thaw major defect increas thaw sampl especi acrosom injuri speci semen contamin urin remark oncilla ejacul reduc sperm cryoresist speci ultrastructur analysi endors morpholog analysi light microscopi identifi cell acrosom vesicul conclus spermatozoa ocelot cryoresist extend commerci non commerci suitabl cryopreserv extend investig oncilla | D012662 | T058;T031;T059 |
34,662,839 | stachi byzantina extract green biocompat molecul sourc graphen skeleton generat carbon steel superior corros mitig presenc bio activ compound stachi byzantina sb extract made power sourc green inhibitor control steel corros studi attempt creat high durabl corros protect film surfac metal sb dival zinc ii cation investig electrochem imped spectroscopi ei potentiodynam polar pp test surfac analysi method ei result show h place steel sampl nacl solut contain sb zn synergist corros inhibit behavior besid result pp demonstr signific reduct corr furthermor surfac analys field emiss scan electron microscopyenergi dispers x ray spectroscopi fe seme atom forc microscopi afm imag illustr low metal surfac degrad indic mix sb zn caus protect layer creation surfac especi sb zn also new compound graphit materi structur made use sb extract natur base chemic investig fourier transform infrar spectroscopi ftir test graze incid x ray diffract gixrd techniqu ultraviolet visibl spectroscopi uv vis analysi raman spectroscopi | D013232 | T122 |
34,662,836 | radiat energi budget dynam associ float photovolta system shortwav radiat longwav radiat photovolta pv panel air near surfac water temperatur data measur float pv system instal shallow tropic reservoir similar air water temperatur measur conduct open water ambient condit comparison data indic shortwav radiat reduc signific pv panel longwav radiat increas fact becam higher shortwav radiat compar open water condit air temperatur water temperatur pv panel higher open water numer model develop predict pv panel temperatur air water temperatur beneath panel investig heat balanc reservoir surfac beneath panel model air pv panel temperatur good agreement field data model surfac water temperatur also replic field measur show increas c compar open water temperatur heat budget analysi show thermal dynam pv panel main control longwav radiat pv panel reduct latent heat flux alter flux condit beneath panel result higher equilibrium temperatur near water surfac compar open water condit | D006358;D014867 | T070;T121;T197 |
34,662,834 | activ traffic manag strategi expressway base crash risk predict move vehicl group activ traffic manag atm strategi use method reduc crash risk improv safeti expressway although studi atm strategi studi take move vehicl group object analysi base crash risk predict move vehicl group connect vehicl cv environ studi develop various atm safeti strategi variabl speed limit vsls ramp meter rm coordin vsl rm vsl rm strategi vsls updat minim crash risk multipl move vehicl group next time interv min updat speed limit sent direct cvs move vehicl group meter rate rm open time determin use mainlin occup crash risk upcom move vehicl group predict time move vehicl group arriv ramp vsl rm strategi use simultan control coordin traffic flow mainlin ramp strategi test well calibr valid micro simul network crash risk index conflict count util evalu safeti effect strategi result indic atm strategi improv expressway safeti benefit increas cv penetr rate would promot safeti benefit vsl vsl rm moreov vsl rm superior vsl rm reduc crash risk conflict count | D000063;D001334 | T056;T037;T067 |
34,662,833 | oral oligofructos challeng reduc express glucos transport adenosin monophosph activ protein kinas lamellar wall holstein heifer claw laminar tissu bovin lamin may undergo energi failur express glucos transport protein glut adenosin monophosph activ protein kinas ampk affect energi metabol digit laminar tissu studi aim determin express glucos uptak ampk laminar wall corium holstein heifer claw oral administr oligofructos total twelv clinic healthi holstein heifer select divid two group includ control con n experiment n group heifer group given gkg bw oligofructos dissolv water mlkg bw heifer con group given water mlkg bw laminar tissu collect euthanasia amount protein transcript express ampk glut determin western blot quantit revers transcript polymeras chain reaction qrt pcr respect express phosphoenolpyruv carboxi kinas pepck receptor c coactiv pgc peroxisom prolifer activ receptor ppar determin qrt pcr heifer group show signific chang express concentr ampk phosphor thr ampk glut signific decreas gene content ppar pgc signific increas activ ampk glut digit laminar tissu heifer inhibit may contribut digit laminar tissu damag | D055372;D009844 | T116;T126;T109 |
34,662,829 | alter neuromuscular activ postur stabil stand balanc task person non specif neck pain compar neck trunk lower extrem muscl activ stand person neck pain np healthi control determin associ postur sway | D019547;D004856 | T040;T184 |
34,662,827 | optim deeper spike neural network dynam vision sens spike neural network snns recent emerg new generat low power deep neural network due spars asynchron binari event driven process previous deep snn optim method focus static dataset eg mnist convent frame base camera hand optim techniqu event data dynam vision sensor dvs camera still infanc prior snn techniqu handl dvs data limit shallow network thus show low perform general observ integr fire behavior spike neuron diminish spike activ deeper layer spars spike activ result sub optim solut train ie perform degrad address limit propos novel algorithm architectur advanc acceler train deep snns dvs data specif propos spike activ lift train salt increas spike activ across layer optim weight threshold convolut layer appli salt train weight base cross entropi loss salt help network convey ampl inform across layer train therefor improv perform furthermor propos simpl effect architectur call switch bn exploit batch normal bn previous method show standard bn incompat tempor dynam snns therefor switch bn architectur appli bn last layer snn accumul spike previous layer spike voltag accumul ie convert tempor spike inform float valu even though appli bn one layer snns result demonstr consider perform gain without signific comput overhead extens experi show effect salt switch bn train deep snns scratch various benchmark includ dvs cifar n caltech dhp cifar cifar best knowledg first work show state art perform deep snns dvs data | D016571;D009474 | T025;T170 |
34,662,826 | construct imin link coval organ framework advanc adsorb sensit determin chlorophenol food safeti great concern general public chlorophenol cps organ pollut found drink water food caus serious harm human health herein imin link coval organ framework cof name tapt cof synthes anilin modul strategi condens triformylphoroglucinol triazin triyl trianilin anilin modul prepar tapt cof possess good crystallin regular morpholog display excel adsorpt capabl toward cps pollut thus tapt cof use novel adsorb line solid phase extract four cps cp cp cps cps bottl water tea drink honey sampl high perform liquid chromatographi ultraviolet detect optim condit wide linear rang low detect limit satisfactori extract recoveri gain stack hydrophob interact tapt cof analyt play import role adsorpt establish method great potenti determin hydrophob aromat compound | D002733;D000073396 | T109 |
34,662,825 | target extract solvent free pressur method base analyt like oxonium salt exampl simultan determin bamboo leaf flavonoid ultra perform liquid chromatographyultraviolet detect use novel oxonium salt sandwich mode improv approach target enrich pressur solvent free extract coupl ultra perform liquid chromatographyultraviolet detect uplc uv analysi develop main bioactiv flavonoid bamboo leav solid extract salt structur nucleus analyt comparison yield new method higher report way highest enrich factor reach whole process consist pseudo second order model r rate constant gmgmin moreov ideal select linear repeat limit detect limit quantif recoveri achiev | D005419;D053719 | T127;T121;T109;T063 |
34,662,824 | compar extract perform cyclodextrin contain supramolecular deep eutect solvent versus convent deep eutect solvent headspac singl drop microextract headspac singl drop microextract hs sdme method coupl high perform liquid chromatographi develop compar extract eighteen aromat organ pollut aqueous solut use cyclodextrin base supramolecular deep eutect solvent supradess alkylammonium halid base convent deep eutect solvent dess differ deriv beta cyclodextrin cd employ hydrogen bond acceptor hba supradess extract perform investig suprad compris wt nativ cd hba provid highest enrich factor analyt compar supradess compris deriv cd random methyl cyclodextrin heptaki tri methyl cyclodextrin hydroxypropyl cyclodextrin addit nativ cd deriv dissolv neat dess effect extract analyt examin dissolut wt nativ cd cholin chlorid ch cl urea des result signific increas extract effici target analyt compar neat ch cl urea des optimum condit extract method requir solvent microdroplet l rpm stir rate wv salt concentr temperatur c tetrabutylammonium chlorid lactic acid des result highest enrich factor ch cl urea des lowest analyt among evalu solvent method provid limit detect lod g l furthermor develop method appli analysi spike tap lake water relat recoveri rang relat standard deviat lower achiev | D003505;D059627 | T130;T059;T109 |
34,662,823 | rapid sensit analyt method determin amoxicillin relat compound water meet requir european union watch list presenc antibiot aquat environ becom one main research focus scientist polici maker proof inclus four antibiot amongst amoxicillin eu watch list wl decis eu substanc water monitor accur quantif amoxicillin water sub ppb level requir wl troublesom due physicochem properti work analyt challeng relat determin amoxicillin six relat penicillin ampicillin cloxacillin dicloxacillin penicillin g penicillin v oxacillin care address includ sampl treatment sampl stabil chromatograph analysi mass spectrometr detect tripl quadrupol given low recoveri obtain use differ solid phase extract cartridg appli direct inject water sampl use revers phase chromatograph column allow work aqueous mobil phase matrix effect evalu correct use isotop label intern standard correct factor base signal suppress observ analysi spike sampl methodolog develop satisfactorili valid ng l seven penicillin studi appli differ type water matric reveal presenc ampicillin one surfac water sampl cloxacillin three effluent wastewat sampl | D000658;D014867 | T195;T121;T109;T197 |
34,662,820 | identif import featur base fuzzi ensembl techniqu evalu joint space narrow progress knee osteoarthr patient featur select fs crucial time challeng process step aim reduc dimension complex classif regress problem various techniqu propos literatur address challeng emphasi medic applic howev one exist fs algorithm come advantag disadvantag introduc certain level bias | D020370 | T047 |
34,662,819 | relev intern bremsstrahlung photon decay experiment mont carlo studi intern bremsstrahlung ib continu electromagnet radiat accompani beta decay howev process consid radiat protect studi particular estim exposur beta decay radionuclid aim present work show neglect ib process mont carlo mc simul lead underestim energi deposit ionize chamber case high energi pure beta emitt yttrium ii determin reliabl choic sourc term ib use mc simul radionuclid common employ nuclear medicin radiochemistri applic experiment data acquir well ionize chamber compar mont carlo mc calcul carri gamo framework simul includ effect ib process found give result underestim experiment valu consequ two model ib energi spectra previous describ italiano et al implement use mc simul good agreement achiev one therefor conclud inclus ib process mont carlo simul packag advis accur complet treatment electromagnet interact | D017785;D011835 | T167;T061 |
34,662,818 | technic note unexpect extern marker artifact k space base parallel imag turbo spin echo magnet reson imag mri radiotherapi plan requir spatial referenc use immobil devic marker clinic imag difficult interpret artifact present resembl metastasi occur combin caipirinha k space base parallel imag pi distort correct extern marker | D016477;D021621 | T062;T060;T073;T068 |
34,662,815 | bio modul mice epitheli endometri organoid low level laser therapi serv invitro model endometri regener endometri regener dynam process well understood destruct endometrium format intrauterin adhes known asherman syndrom lesion rang minor sever adhes impact pregnanc well document oper hysteroscopi mainstay diagnosi treatment intrauterin adhes nevertheless recurr rate remain high record low level laser therapi low dose stimulatori effect differ tissu high dose produc suppress effect organoid three dimension assembl display architectur function similar vivo organ develop human anim stem cell organ specif progenitor self organ process prospect studi effect low level laser therapi lllt mous epitheli endometri organoid regard cell prolifer endometri regener new modal treatment vitro clinic trial generat mous epitheli organoid model test lllt use ne nm devic organoid prolifer function respons ovarian hormon perform tri endometri regener cultur organoid decellular uterin matrix dum studi lllt effect regener process lllt produc prolif effect epitheli mous organoid confirm ki pcna ihc organoid could regener epitheli layer endometrium vitro dum lllt could help process conclus organoid whether control bio stimul prove new modal regener endometrium | D066298;D028022 | T170;T059;T061 |
34,662,814 | fundus imag segment via hierarch featur learn fundus imag segment fis essenti procedur autom diagnosi ophthalm diseas recent deep fulli convolut network wide use fis state art perform repres deep model u net follow encod decod architectur believ suboptim fis consecut pool oper encod lead low resolut represent loss detail spatial inform particular import segment tini vessel lesion motiv high resolut hierarch network hhnet propos learn semant rich high resolut represent preserv spatial detail simultan specif high resolut featur learn hfl modul increas dilat rate first design learn high level high resolut represent hhnet construct incorpor three hfl modul two featur aggreg modul hhnet run coars fine manner fine segment map output last level extens experi conduct fundus lesion segment vessel segment optic cup segment experiment result reveal propos method show high competit even superior perform term segment perform comput cost indic potenti advantag clinic applic | D000077321;D016571 | T170;T066 |
34,662,812 | defici immunoproteasom assembl drive gain synuclein patholog parkinson diseas aberr synuclein syn accumul result proteasom dysfunct consid promin factor initi aggrav neurodegener parkinson diseas pd although involv proteasom proteostasi imbal wide accept knowledg regul immunoproteasom function potenti role syn patholog remain limit immunoproteasom abund proteolyt activ depend fine tune assembl process especi ring format mediat well known chaperon proteasom matur protein pomp identifi syn overexpress associ reduct immunoproteasom function turn limit degrad polo like kinas plk exacerb syn ser phosphoryl aggreg ultim lead neurodegener effect could dramat attenu overexpress mechanist syn suppress transcript regul pomp nuclear factor erythroid relat factor nrf therebi prevent assembl immunoproteasom subunit dopaminerg neuron specif overexpress nrf pomp axi effect rescu aggreg syn pd like phenotyp find character abnorm immunoproteasom assembl key contributor govern syn accumul neurodegener might open new perspect implic immunoproteasom pd provid approach manipul immunoproteasom assembl therapeut purpos | D010300;D051844 | T116;T047;T123 |
34,662,811 | short chain fatti acid modul redox signal health diseas short chain fatti acid scfas produc colon bacteria obtain diet link benefici effect human health associ metabol signal properti physiolog function relat aliphat tail length depend activ specif membran receptor review focus mechan under scfas mediat protect oxid mitochondri stress role regul metabol pathway specif tissu critic evalu evid cytoprotect role suppress inflamm carcinogenesi consequ age abil natur compound induc signal pathway involv nuclear erythroid relat factor nrf contribut mainten redox homeostasi physiolog condit scfas may thus serv nutrit therapeut agent healthi age vascular diseas diabet neuropatholog cancer | D005232;D015398 | T043;T044;T109;T123 |
34,662,808 | spepiprofin master regul develop tooth tooth develop involv coordin transcript regul extracellular matrix protein produc ameloblast odontoblast studi whole genom chip seq analysi appli identifi transcript regulatori gene target sp mesenchym cell develop tooth bioinformat analysi pool sp target peak identifi consensus nine nucleotid bind dna motif ctgataatta consist find number enamel dentin matrix gene includ amelogenin amelx ameloblastin ambn enamelin enam dental sialophosphoprotein dspp identifi contain sp target sequenc sp peak also found import tooth gene includ transcript factor dlx dlx dlx dlx sp sp pitx msx extracellular matrix relat protein cola cola halpn unsupervis umap cluster tooth singl cell rna seq data confirm presenc sp transcript co express mani identifi target gene within ameloblast odontoblast last transcript report assay use promot fragment hapln sp gene reveal sp co express enhanc gene transcript activ taken togeth result highlight sp major regul multipl extracellular matrix gene develop tooth | D018507;D053263 | T044;T045 |
34,662,806 | cross cultur adapt measur properti visa questionnair chines patient achill tendinopathi cultur adapt visa simplifi chines version visa chn test measur properti | D000125;D052256 | T047;T023 |
34,662,804 | cavit facilit transmembran permeabl enhanc induc acoust vapor nanodroplet ultrasound facilit transmembran permeabl enhanc attract broad attent treatment central nervous system cns diseas deliv genedrug deep site brain tissu safer effect way although feasibl use acoust vapor nanodroplet open blood brain barrier bbb previous report relev physic mechan impact factor well known current studi nitrocellulos nc membran use mimic multi layer pore structur bbb cavit activ penetr abil phase chang nanodroplet system evalu differ concentr level compar result obtain sonovu microbubbl passiv cavit detect show less intensifi sustain inerti cavit ic activ would generat vapor nanodroplet microbubbl result suffici high concentr ml phase chang nanodroplet effect microbubbl enabl fluoresc tracer agent fitc kda penetr deeper homogen nc membran posit correl observ accumul ic dose amount penetr fitc vivo studi confirm acoust vapor nanodroplet perform better microbubbl open bbb rat brain result indic phase chang nanodroplet use safe effici durabl agent achiev satisfactori cavit mediat permeabl enhanc effect biomed applic | D045423 | T074 |
34,662,803 | effect ultrasound treatment combin nisin inactiv listeria innocua escherichia coli ultrasound alon combin natur antimicrobi novel food process technolog interest replac tradit food decontamin method milder classic sterilis heat treatment maintain desir sensori characterist howev ultrasound efficaci affect food structurecomposit well order combin treatment appli specif treatment target differ cell compon could result enhanc inactiv appli appropri order microbi properti ie gram positivegram negat also impact treatment efficaci work present systemat studi combin effect ultrasound nisin inactiv bacteria listeria innocua gram posit escherichia coli gram negat rang cavit condit khz order treatment applic vari impact system structur also investig vari concentr xanthan gum use creat food model system wv microbi inactiv kinet monitor advanc microscopi flow cytometri techniqu utilis quantifi impact treatment cellular level ultrasound shown effect e coli khz l innocua demonstr resist frequenc studi enhanc inactiv e coli observ combin nisin ultrasound khz nisin appli ultrasound treatment system structur negat impact inactiv efficaci combin effect ultrasound nisin e coli attribut short live destabilis outer membran result sonic allow nisin penetr cytoplasm membran facilit cell inactiv | D004926;D008087 | T007 |
34,662,802 | intervent address loneli social isol young peopl systemat review evid accept effect loneli preval associ negat health outcom young peopl understand best address limit systemat review aim assess accept effect intervent reduc prevent loneli social isol young peopl | D008132;D012934 | T033;T054 |
34,662,801 | nonspecif symptom follow infect borrelia burgdorferi sensu lato retrospect cohort studi whether infect borrelia burgdorferi sensu lato sl caus nonspecif symptom matter controversi investig whether individu infect b burgdorferi sl develop unspecif symptom frequent non infect control eighti nine person present b burgdorferi sl infect ask particip infect defin erythema migran diagnos either cours previous studi medic visit outpati depart seroconvers asymptomat subject control group consist seroneg individu without erythema migran past two half year later particip ask fill questionnair list nonspecif symptom data person previous borrelia infect uninfect control avail analysi muscl pain signific p frequent control group fatigu occur often infect group statist signific p likewis distribut symptom differ consider analysi reveal differ frequenc symptom person em asymptomat borrelia infect year prior assess comparison person without borrelia infect | D025065;D015748;D015787;D008193 | T007;T047 |
34,662,800 | effect radiofrequ electromagnet field rf emf biomark oxid stress vivo vitro protocol systemat review oxid stress conjectur relat mani diseas furthermor hypothes radiofrequ field may induc oxid stress various cell type therebi compromis human anim health systemat review sr aim summar evalu literatur relat hypothesi | D004574;D011846 | T070 |
34,662,799 | ecolog spatial variat legaci emerg contamin white tail sea eagl germani implic prioritis futur risk manag increas use chemic european union eu result environment emiss wildlif exposur approv chemic within eu produc need conduct environment risk assess typic reli data generat laboratori condit without consid ecolog landscap context address gap add inform emerg contamin chemic mixtur analys liver white tail sea eagl haliaeetus albicilla northern germani high resolut mass spectrometri coupl liquid gas chromatographi identif contamin model influenc trophic posit n habitat c landscap chemic residu screen persist bioaccumul toxic pbt properti use silico model unravel mismatch predict pbt properti observ exposur despit general low pbt score detect contamin medicin product oxfendazol salicylamid frequent chemic stockholm convent dde pcbs present sampl toxic threshold among pfas especi pfos show elev concentr compar studi contrast pfca level low increas n indic increas prey piscivor speci among plant protect product spiroxamin simazin frequent detect increas concentr agricultur landscap silico model proven reliabl predict pbt properti chemic howev chemic exposur apex predat complex sole reli intrins chemic properti also factor ecolog landscap therefor recommend ecolog context mixtur toxic chemic monitor data frequent consid regulatori risk assess eg weight evid approach trigger risk manag measur advers effect individu popul start manifest | D020307;D011078 | T131;T109;T012 |
34,662,798 | urban environ cognit motor function children four european birth cohort urban environ may influenc neurodevelop concept onward evalu impact multipl group exposur simultan investig associ earli life urban environ cognit motor function children | D000393;D000397 | T131;T069;T080 |
34,662,797 | multispectr fluoresc sensit acid polyphenol chang chardonnay wine case studi malolact ferment studi stationari time resolvedfluoresc signatur statist chemometr analyz among three typolog chardonnay wine b c object evalu sensit acid polyphenol chang purpos dataset built use excit emiss matric fluoresc n decompos parallel factor analysi parafac andfluoresc decay n mathemat fit use convent exponenti model phasor plot represent wine parafac compon c coupledwith phasor plot g valu enabl descript malolact ferment mlf occurr chardonnay wine proxi reflect wine concentr modif total acid maliclact phenol acidslow g valu among fresh mlf wine compar mlf wine explain quench effect wine fluorophor organ phenol acidsth combin multispectr fluoresc parametersopen novel routin implement methodolog diagnos ferment process | D014920 | T168 |
34,662,796 | applic deep eutect solvent base extract coupl cqd fluoresc sensor determin pirimicarb cereal novel deep eutect solvent base extract sulfur dope carbon quantum dot cqds serv fluoresc probe detect pirimicarb cereal establish deep eutect solvent synthes use cholin chlorid butanediol achiev direct effici extract pirimicarb residu cereal fluoresc quench cqds caus electrostat interact negat charg cqds posit charg thiocholin hydrolys acetylthiocholin fluoresc cqds enhanc activ acetylcholinesteras ach inhibit pirimicarb achiev detect pirimicarb cereal sampl limit detect lod g ml recoveri rang extract detect method pirimicarb base environment friend des cqd fluoresc sensor maintain good stabil conveni offer promis strategi extract test harm substanc food sampl | D002523;D045663 | T168;T073 |
34,662,795 | develop label free plasmon gold nanoparticl aggreg sensor basi charg neutral detect zearalenon mycotoxin contamin corn consid serious problem accumul differ organ tissu via ingest skin contact caus sever health problem human construct label free colorimetr fluoresc dual channel sens platform detect zearalenon demonstr plasmon gold nanoparticl aggreg could rapid form basi charg neutral posit charg sybr green sens platform allow quantit detect low g kg visual detect low g kg charg neutral strategi elimin major sourc instabl convent gold nanoparticl colorimetr measur pave way accur label free bioanalysi | D053768;D009183;D015025 | T131;T073;T109 |
34,662,794 | character polysaccharid pleurotus eryngii simul gastrointestin digest ferment pleurotus eryngii valuabl new edibl mushroom varieti cultiv larg scale china polysaccharid found mushroom strong bioactiv studi use simul digest ferment model studi digest ferment characterist pleurotus eryngii polysaccharid pep effect gut microbiota result show molecular weight pep remain unchang simul digest overal structur pep destroy indic pep decompos digest howev ferment pep degrad util intestin flora produc varieti short chain fatti acid scfas reduc ph valu fecal cultur meanwhil pep regul composit intestin flora relat abund firmicut increas signific suggest pep use function food promot intestin health prevent diseas | D020076 | T004 |
34,662,793 | target mangiferin load n succinyl chitosan algin graft nanoparticl atherosclerosi case studi diabet mediat hyperlipidemia rat mangiferin mgf mangifera indica well report hypoglycem activ hypolipidem activ howev mgf suffer therapeut limit due poor solubl caus disparag bioavail herein address problem incorpor mgf algin graft n succinyl chitosan nsc nanomatrix character molecular dock ft ir nmr cosi reveal mgf could reinforc interact nsc oh ch oh group mgf may set interact pyranos oh ch oh nh nh succinyl cooh succinyl nsc nsc mgf nanoconjug reveal spheric particl geometri nm size encapsul mgf show releas vitro vivo nsc mgf nanoconjug reveal blood glucos lower mgdl mgdl well lower total plasma cholesterol well compar earlier report acknowledg lower plasma cholesterol mgf furthermor nsc mgf lower serum trigycerid earlier studi serum triglycerid reduct found solitari mgf | D050197;D048271;D003920;D006949;D053758 | T047;T121;T109;T073;T046;T033 |
34,662,792 | inform display brazilian food bar label point need reformul current food label legisl articl compar inform label brazilian food bar nation health surveil agenc legisl twenti six brand food bar identifi compris commerci line flavor market appeal consum front pack label appear mani way identifi product healthi sustain lifestyl howev mandatori inform hard see packag onlin make difficult consum access inform label follow current legisl nutrit irregular identifi sinc bar ultra process one incorrect inform label claim food healthi reinforc need reformul nutrit label brazil facilit identif nutrit qualityvalu food part healthi sustain diet | D005515;D007881 | T057;T089;T068 |
34,662,791 | use veget enhanc oxid stabil omega oil powder state preliminari studi examin effect various veget stabilis omega oil powder oxid deterior pure made differ veget mushroom brussel sprout broccoli cauliflow snow pea tomato garlic employ prepar veget tuna oil emuls subsequ freez dri powder oxipr data show veget tuna oil powder longer induct period neat tuna oil acceler oxid storag cweek eicosapentaeno docosahexaeno acid veget tuna oil powder protect oxid lower level headspac secondari tertiari oxid product whole veget pure suitabl protect matric omega oil various veget pure examin protect effect omega oxid mushroom brussel sprout broccoli cauliflow superior snow pea garlic tomato antioxid properti phytonutri inher various veget like contributor protect omega oil powder oxid | D015525;D014675 | T121;T168;T109;T123 |
34,662,790 | facil synthesi au ag core shell nanorod bimetal synergist effect ser detect thiabendazol fruit juic studi present effect sensit ser substrat rapid detect thiabendazol tbz fruit sampl core shell goldsilv nanorod au ag nrs synthes bimetal ser activ substrat obtain substrat show excel ser effect tunabl plasmon reson au nrs signific enhanc effect silver bimetal synergist effect au ag nrs optim condit substrat use detect tbz fresh appl juic peach juic limit detect ppm respect addit recoveri rate within satisfactori rang indic au ag nrs substrat could ser detect platform fruit pesticid residu great develop potenti | D053768;D043942 | T073 |
34,662,788 | zero valent iron improv methan product specif reduc aminoglycosid tetracyclin resist gene anaerob digest unadvis discuss antibiot resist gene arg reduct anaerob digest ad system neglect main purpos methan product methan product improv coupl antibiot resist gene arg reduct anaerob digest ad zero valent iron zvi simultan investig whether role zvi arg fate random specif clarifi high throughput qpcr ht qpcr result indic zvi improv methan product arg reduct respect improv methan product associ chemic reaction varianc microbi communiti caus zvi diet petrimona clostridium syntrophomona methanosarcina establish along aca enrich zvi specif random facilit reduct aminoglycosid resist gene antibiot inactiv tetracyclin resist gene ribosom protect protein specif reduct could attribut enzym activ inhibit intracellular ionic disturb caus higher amount zvi although arg fate could well explain microbi communiti contribut arg dynam whole zvi base ad promis way improv methan product coupl arg reduct | D000617;D007501 | T196;T121;T109;T123 |
34,662,787 | lignit dewat lignit modifi subbitumin coal reduc nitrogen loss broiler litter broiler litter generat larg quantiti wast product chicken meat product n may lost litter emit bird hous gaseous nh damag environ limit recycl valuabl nutrient studi investig effect lignit applic rate n loss broiler litter static chamber laboratori incub lignit subsequ dewat subbitumin coal modifi aerob thermal oxid ammoniac n adsorpt potenti characteris second static chamber incub capac materi appli reduc n loss litter investig final potenti direct reduc nh emiss examin use chamber acid trap system studi show lignit reduc n loss appli litter rate amount n retain increas increas lignit applic rate litter treat lignit retain n untreat litter follow aerob thermal treatment maximum ammoniac n adsorpt capac materi follow lignit dewat lignit modifi subbitumin coal subbitumin coal despit inequ adsorpt capac lignit dewat lignit modifi subbitumin coal reduc total n loss nh emiss respect studi demonstr potenti coal base materi reduc nh emiss broiler litter increas nutrient valu wast reduc n loss | D003031;D009584 | T121;T109;T123;T167;T196 |
34,662,786 | perform evalu em system use queu theori locat analysi case studi emerg medic servic em respons time key factor show perform system factor compos two part includ activ time travel time activ time emerg call time call center spend take incom call em decid whether ambul dispatch emerg resolv give medic advic good number call center oper includ call taker dispatch help reduc time thus respons time howev alon may enough reason cycl time fact idl ambul locat right place emerg call occur influenti factor reduc travel time thus optim respons time save peopl live although mani research studi improv either activ time travel time best knowledg exist studi focus motiv gap studi framework propos use queu theori locat analysi address activ travel time regard first queu theori appli evalu perform em call center reduc averag activ time three mathemat model includ mobil station mexclp mecrp appli locat ambul averag travel time minim shed light merit use queu theori locat model comput result base real world data tehran em center provid propos methodolog reduc averag respons time approxim four minut increas averag coverag work exampl tremend posit impact applic queu theori mathemat model propos framework signific decreas cycl time increas ambul coverag level find studi help polici maker em center evalu perform system determin optim number oper locat ambul way enhanc qualiti emerg servic | D000552;D000070456;D004632 | T073;T074;T058;T093;T061;T092 |
34,662,785 | develop prehospit predict model risk stratif patient chest pain chest pain one common reason contact emerg medic servic em chest pain patient high risk condit mani low risk condit need acut hospit care challeng earli stage distinguish whether patient low high risk condit object studi develop predict model optimis identif patient low respect high risk condit acut chest pain earli em work flow | D004632 | T058;T093;T061 |
34,662,784 | reemerg engel concept social murder respons grow social health inequ friedrich engel identifi live work condit experienc english worker sent prematur grave argu respons condit rule author bourgeoisi commit social murder concept remain part dormant academ journal sinc reviv social murder concept growth especi evid uk last decad result grenfel tower fire effect auster impos success conserv govern purpos paper document reemerg concept social murder academ journal articl conduct scope review content appli social murder concept sinc relat health well identifi two primari concept social murder social murder result capitalist exploit social murder result bad public polici across domain work condit live condit poverti hous race health inequ crime violenc neoliber gender food social assist deregul auster consid reason reemerg engel social murder concept role play resist forc respons live work condit kill | D054624;D011203 | T080;T102;T098;T064 |
34,662,783 | dropdown right categor transgend discrimin healthcar technolog studi analyz us healthcar organ implement legal requir treat patient manner consist gender ident section afford care act way healthcar organ determin gender track complaint constitut socio technic system complianc shape discrimin protect look like ground interview grievanc handler use inform technolog process possibl civil right claim patient argu work demobil eras civil right especi claim transgend harass mobil physician led implement group contrast enact version gender ident recognit track ident bodi electron medic record materi object specimen label default structur dropdown menus healthcar softwar shape shape profession norm financi incent concept justic deserving socio technic structur allow conflict stori transgend right continu differ part healthcar organ make difficult law transform healthcar deliveri | D063106 | T098 |
34,662,782 | thorac surgeri improv overal surviv patient stage iiib iv epiderm growth factor receptor mutant lung adenocarcinoma receiv respond tyrosin kinas inhibitor treatment larg scale prospect random studi evalu effect thorac surgeri patient unresect stage iiib iv epiderm growth factor receptor egfr mutant lung adenocarcinoma receiv respond egfr tyrosin kinas inhibitor tki treatment therefor design propens score match nationwid popul base cohort studi investig effect thorac surgeri patient egfr mutant lung adenocarcinoma | D000077192;D008175;D013903 | T091;T191 |
34,662,781 | liquid chromatograph studi two structur isomer pentacycl triterpen revers phase stationari phase hydroxypropyl cyclodextrin mobil phase addit retent behavior two structur isomer pentacycl triterpen acid maslin acid corosol acid investig revers phase high perform liquid chromatographi hplc hydroxypropyl cyclodextrin hp cd mobil phase addit inclus complex maslin acid corosol acid hydroxypropyl cyclodextrin evalu differ concentr hydroxypropyl cyclodextrin appar format constant k methanol hydroxypropyl cyclodextrin determin l mol c use uv spectrophotometri two retent model employ individu evalu inclus complex two pentacycl triterpen acid hydroxypropyl cyclodextrin found higher appar format constant k f corosol acid hydroxypropyl cyclodextrin obtain l mol indic greater affin hydroxypropyl cyclodextrin corosol acid produc compar maslin acid l mol select mobil phase stoichiometr ratio inclus complex found thermodynam analysi show negat standard enthalpi chang h entropi chang analyt transfer obtain h maslin acid corosol acid found kj mol kj mol two compound respect indic transfer structur isom mobil phase stationari phase enthalp driven meanwhil posit valu obtain standard enthalpi chang standard entropi chang kj mol kj mol j mol k j mol k inclus complex maslin acid corosol acid hydroxypropyl cyclodextrin negat valu obtain gibb free energi format inclus complex kj mol kj mol indic spontan inclus reaction happen | D047392 | T109 |
34,662,780 | fluorescein isothiocyan dope conjug polym nanoparticl two photon ratiometr fluoresc imag intracellular ph fluctuat herein report two photon ratiometr fluoresc ph nanosensor base conjug polym poli di n octylfluorenyl diyl pfo nanoparticl load ph sensit fluorescein isothiocyan fitc intracellular ph monitor obtain nanosensor fitc pfo nps possess high sensit excel stabil good revers favor two photon excit low cytotox ratiometr fluoresc fitc pfo f f fitc pfo nps solut show effici ph sensit respons ph rang pka two photon excit addit fitc pfo nps success appli ratiometr imag intracellular ph fluctuat one photon two photon excit mode overal two photon ph nanosensor base fitc pfo nps exhibit great potenti crucial physiolog biolog process relat intracellular ph fluctuat | D053758;D011108 | T104;T122;T073 |
34,662,779 | frequenc specif network activ predict bradykinesia sever parkinson diseas bradykinesia associ beta gamma band interact basal ganglia thalamo cortic circuit parkinson diseas present cross section studi aim search neural network electroencephalographi whose frequenc specif action may predict bradykinesia | D046690;D010300;D020531 | T023;T047;T061 |
34,662,778 | salienc network glutam brain connect medic nave first episod patient multimod magnet reson spectroscopi rest state function connect mri studi salienc network sn connect alter schizophrenia pathophysiolog origin remain poor understood goal multimod neuroimag studi investig role glutamaterg metabol putat mechan under sn dysconnect first episod psychosi fep subject | D018698;D011618 | T116;T121;T048;T123 |
34,662,777 | studi protocol assess polypharmaci comorbid lung cancer least half patient lung cancer comorbid affect treatment decis surviv associ comorbid polypharmaci also consequ patient care studi evalu polypharmaci comorbid cohort hospit patient administr chemotherapi surviv | D008175;D019338 | T191;T061 |
34,662,776 | prosoci social dilemma antibiot prescrib antibiot prescrib conceptualis social dilemma overus antibiot minimis immedi risk individu patient result sub optim outcom societi antimicrobi resist increas risk patient long run doctor face challeng balanc interest individu patient collect good prescrib antibiot evid suggest doctor tend prioritis individu interest collect convent interpret decis selfish may inappropri doctor motiv prosoci concern patient review antibiot decis research provid nuanc understand prosoci context social dilemma antibiot prescrib | D000900;D010820 | T097;T195;T121 |
34,662,775 | peer network studi intervent adolesc peer influenc occur across wide varieti behavior domain import reason peer led intervent intervent peer involv deliveri program program promis combat undesir behavior eg risk behavior promot desir behavior eg healthi lifestyl shown recent effect program modest best mechan under program effect poor understood research need promot understand relat cumul interact impact differ type peer relat unpack various mechan under peer select influenc potenti yield insight advanc theori optim peer led intervent | D000294;D010379 | T098;T055 |
34,662,774 | relat mind prosoci behavior know mind hot topic psycholog research popular media one central claim literatur enhanc mind foster prosoci behavior articl recapitul current known widespread claim first review theoret perspect enhanc mind foster prosoci behavior discuss relev empir evid two meta analys provid preliminari support claim howev limit call caution interpret evid studi investig effect persist sustain period time miss addit theoret assumpt under mechan need stronger empir support discuss theoret predica identifi potenti downsid mind suggest way forward futur research | D064866 | T041 |
34,662,773 | effect advers advantag childhood experi adult health low incom sampl previous studi indic advantag childhood experi counter ace may improv health adulthood regardless advers childhood experi ace score howev studi primarili conduct low risk communiti littl known whether result similar low incom set | D000076783;D011203 | T033;T102;T098;T064 |
34,662,771 | risk respons adapt de intensifi treatment hpv associ oropharyng cancer optima paradigm expand experi favor prognosi human papillomavirus associ hpv oropharyng cancer opc led investig respons adapt de escal yet long term outcom unknown present expand experi follow riskrespons adapt treatment de intensif hpv opc | D009959;D030361 | T191;T047 |
34,662,769 | mandibular advanc devic design systemat review outcom obstruct sleep apnea treatment obstruct sleep apnea osa often treat mandibular advanc devic mad unclear whether particular design featur superior other term osa allevi order facilit clinic decis make systemat review summar object subject outcom differ avail mad design studi compar differ mad design osa treatment search screen titl abstract origin rcts six cohort studi includ articl systemat review meta analysi decreas ahi signific differ mad design clinic relev observ differ howev limit monoblock applianc perform favor compar bilater thrust effect size ci midlin traction applianc perform favor compar design custom applianc perform favor compar thermoplast applianc effect size ci furthermor clinic relev differ mad design reduct ess complianc prefer side effect cost effect respect includ trial present one superior custom mad design osa treatment regard effect ahi reduct ess improv complianc prefer side effect cost effect diseas relat outcom confirm custom mad design perform superior thermoplast mad design | D019186;D020181 | T047;T061 |
34,662,768 | one step fabric au ag alloy applic catalyst ser sensor au ag alloy nanoparticl nps control size composit synthes facil one pot hydrotherm method various character techniqu includ tem uv vis edx haadf stem xps use discuss influenc factor size composit au ag alloy nps obvious size composit au ag alloy nps could adjust experiment paramet catalyt ser perform au ag alloy nps investig ideal catalyt ser perform could also obtain via optim size composit au ag alloy work import theori research practic applic nobl metal nanocomposit | D000497;D053768 | T073;T197 |
34,662,767 | extract fraction musa paradisiaca flower osteogen effect prevent ovariectomi induc osteopenia osteoporosi asymptomat bone disord lead alter bone microarchitectur miner strength musa paradisiaca report antioxid anti inflammatori effect various diseas impact postmenopaus osteoporosi investig yet | D001851;D028521 | T047;T168;T002 |
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