PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,673,431 | occurr character sourc risk assess petroleum relat hydrocarbon sediment along st clair river ontario canada total petroleum hydrocarbon tph n alkan petroleum biomark polycycl aromat hydrocarbon pah analyz sediment collect shorelin bottom st clair river ontario canada sampl site low tph gg river bottom sediment usual higher level tphs total alkan total biomark total pah shorelin one mix biogen petrogen n alkan present site site trace amount petroleum biomark mix pyrogen petrogen input predomin petroleum contribut detect pah sampl site pah detect would show potenti toxic benthic organ shorelin sampl site howev light molecular weight pah eg phenanthren methyl naphthalen acenaphthylen anticip possibl advers impact sediment dwell organ part river bottom sediment | D010578;D011084;D014874 | T131;T109 |
34,673,430 | feasibl sourc identif dom fingerprint marin pollut event accur sourc identif first step pollut control environment emerg manag especi marin pollut event dissolv organ matter dom absorpt fluoresc excit emiss matric eem analys appli trace contamin sourc pollut event occur along coast laizhou bay bohai sea parallel factor analysi parafac eem identifi four fluoresc compon terrestri humic like c tryptophan like c mixtur terrestri marin humic like c tyrosin like c compon relationship among c c qualiti indic indic dom origin terrestri input biolog activ eem parafac result accompani optic characterist dom fingerprint demonstr marin pollut event occur enterpris emiss numer simul confirm reliabl eem parafac model dom fingerprint pollut sourc pollut region studi provid feasibl method sourc recognit marin pollut event | D000090422;D006812 | T109;T123 |
34,673,429 | ingest plastic debri coastal pelag bird along coast esprito santo eastern brazil although ingest plastic anthropogen debri seabird global problem studi employ standard protocol quantifi classifi debri ingest seabird southwest atlant evalu ingest marin debri item mm coastal pelag bird speci along coast esprito santo eastern brazil debri found bird examin speci particl g plastic debri record five speci atlant yellow nose albatross thalassarch chlororhyncho cori shearwat calonectri boreali manx shearwat puffinus puffinus brown boobi sula leucogast magellan penguin spheniscus magellanicus find suggest ingest marin debri especi plastic common problem coastal pelag bird tropic southwest atlant water | D010969;D046429 | T167;T012 |
34,673,428 | baselin assess ocean ambient nois western clarion clipperton zone pacif ocean ocean nois western clarion clipperton zone pacif ocean record min everi hour depth month hour mean spectrum level hz band calcul along skew kurtosi percentil distribut spectral probabl densiti high nois level low frequenc generat distant ship vocal whale found rang db hz typic domin wind found low rang db frequenc hz nois level winter approxim db higher summer consist season variat wind speed fin whale blue whale fish also potenti contribut variat baselin ambient nois | D009622;D014828 | T055;T069;T067 |
34,673,427 | bioaccumul trophic magnif short chain chlorin paraffin marin organ east china sea new persist organ pollut short chain chlorin paraffin sccps recent receiv particular attent howev knowledg bioaccumul trophic magnif marin organ east china sea ec still scare studi investig concentr sccps seawat n marin organ n collect ec total concentr sccps sccps rang ngl seawat ngg wet weight ww organ c sccps cl sccps predomin homologu sampl mean proport seawat well marin organ respect logarithm bioaccumul factor log baf valu sccps rang zooplankton fish shrimp crab shellfish snail cephalopod log baf valu sccp homologu increas signific increas logarithm octanol water partit coeffici log k ow valu indic hydrophob major factor control bioaccumul sccps trophic magnif factor tmf valu sccps calcul indic potenti trophic magnif sccps marin food web ec slight increas trend observ tmf valu sccp homologu log k ow valu overal first time studi systemat examin bioaccumul trophic magnif sccps marin food web east china sea | D006843;D010232 | T121;T073;T109 |
34,673,426 | recalibr depart nation defenc approach activ sonar impact manag field well train combat readi militari observ canada respons environment steward time conflict prioriti depart nation defenc dnd new low frequenc sourc introduc servic dnd must review updat polici procedur regard use activ sonar minim impact marin mammal evid base approach risk mitig primarili avoid requir understand marin mammal distribut order avoid sensit speci habitat parallel research develop program evalu develop technolog solut minim risk harm first embrac empir framework assess acut chronic impact dnd abl partner govern depart research develop technolog target toward residu risk marin mammal pose sonar oper | D002591;D013016 | T070;T015 |
34,673,425 | jkst novel multikinas modul bcr ablstat signal pathway potenti direct bcr abl inhibit overcom imatinib resist chronic myelogen leukemia chronic myelogen leukemia cml hematolog malign high depend bcr ablstat signal pathway cell surviv first line treatment cml consist tyrosin kinas inhibitor effici target bcr abl activ howev drug resist intoler still therapeut limit ph cell therefor develop new anti cml drug exhibit altern mechan overcom limit desir goal work antitumor activ jkst naphthoquinon pyron hybrid assess imatinib sensit imatinib resist human cml cell live cell imag analysi reveal jkst potent antiprolif activ cml cultur jkst provok cell increas subg phase along reduct gg phase alter express key protein involv control mitosi dna damag rapid increas annexin v stain activationcleavag caspas observ jkst treatment cml cell interest jkst inhibit bcr ablstat signal oncokinas downregul preced rapid polyubiquitin addit jkst caus transient increas jnk akt phosphoryl wherea phosphoryl p mapk src reduc combinatori treatment unveil synergist effect imatinib jkst notabl jkst maintain antitumor efficaci bcr abl ti posit cell cml cell overexpress bcr abl even restor imatinib efficaci short exposur time find togeth observ low toxic jkst reveal novel multikinas modul might overcom limit bcr abl inhibitor cml therapi | D019008 | T042;T038 |
34,673,424 | psycho cardiolog therapeut effect shuangxinfang rat depress behavior post acut myocardi infarct focus protein sa proteom depress disord induc acut myocardi infarct ami play pivot role deterior cardiac function shuangxinfang psycho cardiolog formula pcf report allevi heart function damag improv depress like behavior complex mechan process clarifi | D040901 | T091 |
34,673,421 | adrenoreceptor agonist amelior mechan allodynia paclitaxel induc neuropath pain via induct mitochondri biogenesi chemotherapi induc neuropath pain debilit common side effect cancer treatment far effect drug avail treatment serious side effect previous studi demonstr adrenoreceptor adrb agonist attenu neuropath pain howev role adrb paclitaxel induc neuropath pain pinp remain unclear studi investig effect formoterol long act adrb agonist relat mechan pinp rat model pinp establish intraperiton inject paclitaxel mgkg everi day final cumul dose mgkg hind paw withdraw threshold pwts respons von frey filament stimuli use evalu mechan allodynia western blot use examin express adrb peroxisom prolifer activ receptor coactiv pgc nuclear respiratori factor nrf mitochondri transcript factor tfam immunofluoresc detect cellular local adrb pgc spinal cord moreov measur mitochondri dna mtdna copi number qpcr studi formoterol attenu establish pinp delay onset pinp formoterol restor adrb express well mtdna copi number pgc nrf tfam protein express major gene involv mitochondri biogenesi spinal cord pinp rat moreov found analges effect formoterol pinp partial abolish pgc inhibitor sr collect result demonstr activ adrb formoterol amelior pinp least partial induct mitochondri biogenesi | D001678 | T043;T070 |
34,673,420 | factor associ success follow transcerv innomin arteri suspens aortopexi includ innomin arteri suspens well establish treatment anterior vascular compress associ tracheomalacia report result case seri cervic approach innomin arteri suspens hypothes increas distanc innomin sternum predict superior symptomat outcom | D014135;D055090 | T047 |
34,673,419 | systemat review pediatr mandibular arterioven malform manag arterioven malform avm challeng pediatr popul utmost import keep mind various manag option lesion disastr outcom systemat review treatment avm describ current practic practition awar current report literatur challeng avm manag mitig approach patient multidisciplinari team base approach | D001165;D004621 | T019;T061 |
34,673,418 | potassium enhanc cadmium resist abil panax notoginseng brassinolid signal pathway regul cell wall pectin metabol mechan potassium k attenu cadmium cd induc demethyl anabol cell wall cw pectin brassinolid br signal pathway verifi panax notoginseng burk p notoginseng pectin methylesteras gene pnpme clone function verifi tobacco pectin br metabol cd content pectin methyl degre pmd detect respons k epibrassinolid ebl brassinazol treatment p notoginseng tobacco cd stress activ main root pectin methylesteras enzym pme promot ebl treatment cd content increas cd stress potassium reduc pme activ cd content main root pectin respect ebl cd co treatment potassium inhibit promot effect cd stress express pnpme potassium also inhibit express br synthesi gene pndet pnrot pncypa pnbrox respect reduc accumul cd pnpme locat cw activ transgen tobacco root pme higher wild type pmd signific lower regulatori effect k ebl tobacco root pectin metabol consist p notoginseng conclus k downregul express br synthesi gene p notoginseng root cd stress reduc product brs inhibit pnpme express reduct pme activ increas pmd reduc accumul cd | D002104;D053723 | T131;T002;T196 |
34,673,417 | explor toxic age styren butadien rubber microplast petroleum hydrocarbon degrad bacteria compound pollut system new pollut microplast increas drawn public attent toxic behavior environ aim investig effect styren butadien rubber microplast msbr differ degre age petroleum hydrocarbon phc degrad bacteria environ simultan exist pollut seri experi carri investig chang physic chemic properti msbr age examin influenc chang inhibit phc degrad bacteria msbr vicin coexist pollut result show earli stage ultraviolet age particl surfac show wrinkl structur intact reach late stage age nano scale fragment generat surfac msbr averag particl size decreas zeta potenti increas mv mv inhibitori effect bacteria greater time chang physicochem properti increas adsorpt effect cd also improv stabil msbr solut wherebi bacteri growth inhibit inhibit lpo activ protein concentr phc degrad bacteria | D010578;D059392;D014874 | T131;T069;T109 |
34,673,416 | mixtur predict effect concentr deriv independ action model vs concentr addit model base differ speci sensit distribut model hazard assess mixtur mixtur predict effect concentr mpnec alway deriv concentr addit ca model mpnec ca assess risk mixtur combin exposur assess howev independ action ia model also wide use ca model predict evalu mixtur toxic alway use calcul popul fraction show predefin effect mpnec limit applic ia model mixtur risk assess studi explor process mpnec deriv ia method mpnec ia base speci sensit distribut ssd compar mpnec ia mpnec ca take two common pesticid dimetho dim dichlorvo dic expos actual water environ exampl ssd model construct separ use nine distribut function toxic data screen qualiti test dic dim differ nine model pass kolmogorov smirnov test pnec two pesticid deriv base ssd model final mpnec ia differ concentr ratio deriv compar mpnec ca base combin nine ssd model mpnec valu deriv ia model conserv ca worth note mpnec ia conserv mpnec ca common use log logit distribut function log normal distribut log weibul distribut studi provid new direct applic ia risk assess enrich framework mixtur risk assess | D010575 | T131 |
34,673,415 | perform mechan degrad typic antibiot antibiot resist gene magnet resin mediat uv fenton process incomplet remov antibiot antibiot resist gene arg often report wastewat treatment plant effici treatment process need reduc risk environ herein evalu degrad antibiot arg use magnet anion exchang resin maer uv fenton catalyst sulfamethoxazol smz ofloxacin ofx amoxicillin amx select target compound three antibiot almost complet degrad follow maer uv fenton reaction min degrad mechan studi found fe fe could cyclic transfer catalyst permeabl interfac photo generat electron could effect separ domin reactiv radic antibiot degrad hydroxid maer uv fenton reaction degrad pathway sulfamethoxazol propos addit wastewat sampl wastewat treatment plant appli investig remov effici antibiot arg maer uv fenton system rapid decreas antibiot arg level observ reaction system result studi suggest maer mediat uv fenton reaction could appli effect remov antibiot arg wastewat | D000900;D018508 | T052;T195;T121;T057 |
34,673,414 | effect rnai mediat plasma membran calcium transport atpas inositol trisphosph receptor gene silenc suscept mythimna separata wilforin wilforin compound sesquiterpen alkaloid isol tripterygium wilfordii exhibit excel insecticid activ mythimna separata order clarifi action mechan wilforin plasma membran calcium transport atpas pmca inositol trisphosph receptor ip r separata studi result show open read frame msip r mspmca bp bp length well encod amino acid respect multipl sequenc align phylogenet analysi reveal msip r mspmca high homolog ip r pmca insect low similar mammal mean ip r pmca potenti novel target insecticid high select mammal insect msip r mspmca gene exist throughout life cycl separata predomin express somat muscl fifth instar larva adult suscept pmca silenc separata wilforin signific lower normal separata illustr pmca could one target wilforin howev suscept ip r silenc separata wilforin chang signific compar suscept normal separata show wilforin may interact ip r protein find provid clue elucid insecticid mechan wilforin | D007306;D009036 | T131;T204 |
34,673,413 | respons jnk signal pathway toxic dinoflagel prorocentrum lima mussel perna viridi diarrheic shellfish poison dsp toxin wide distribut world caus diarrhea vomit even tumor human howev bivalv main carrier dsp toxin toler mechan dsp toxin though remain unclear studi scrutin role jun n termin kinas jnk toler dsp toxin relationship jnk apoptosi nuclear factor e relat factorantioxid respons element nrfare pathway found phosphoryl level jnk protein signific increas hemocyt h gill h mussel perna viridi short term exposur dsp toxin produc dinoflagel prorocentrum lima exposur p lima induc oxid stress mussel hemocyt gill display differ sensit cytotox dsp toxin exposur p lima activ caspas induc apoptosi gill induc caspas apoptosi hemocyt short term exposur p lima could activ nrfare signal pathway hemocyt h longer term exposur could induc glutathion reductas gr express hemocyt h glutathion transferas gst gill h base phylogenet tree nrf nrf p viridi close relat mussel especi mytilus coruscus far mus musculus like phosphoryl site nrf mussel p viridi threonin jnk differ musculus taken togeth toler mechan p viridi dsp toxin might involv jnk nrfare signal pathway jnk play key role mechan find provid new clue understand toler mechan bivalv dsp toxin | D004141;D049883 | T204 |
34,673,412 | studi reproduct toxic mechan tri n butyl phosphat tnbp caenorhabd elegan tri n butyl phosphat tnbp typic alkyl organophosph ester wide use emerg flame retard polybromin diphenyl ether altern potenti toxic mechan unclear studi reproduct toxic tnbp relat mechan explor use caenorhabd elegan c elegan model tnbp gl exposur brood size number fertil egg uterus c elegan signific reduc relat area gonad arm number total germlin cell c elegan signific reduc germ cell apoptosi germ cell dna damag c elegan signific increas level ros c elegan signific increas furthermor tnbp exposur caus abnorm gene express cell apoptosi ced ced ced dna damag hus clk cep egl oxid stress mev gas tnbp exposur lead reproduct abil decreas gonad develop impair c elegan mechan tnbp reduc reproduct abil may relat germ cell apoptosi germ cell dna damag oxid stress environment exposur tnbp may potenti reproduct toxic | D017173;D029742 | T204;T116 |
34,673,411 | transcriptom analysi reveal antioxid defens mechan red swamp crayfish procambarus clarkia exposur chromium chromium cr chromat anion strong redox capac serious threaten ecolog environ human health cr contamin water impart toxic aquat speci procambarus clarkii import food sourc repres larg proport aquacultur industri due rapid reproduct high econom valu howev report death p clarkii due heavi metal pollut under mechan regard heavi metal toxic studi paper transcriptom data hemocyt extract p clarkii inject cr analyz high throughput sequenc compar control group total clean read obtain treatment group clean read obtain control group read assembl use triniti identifi unigen annot differenti express gene deg found upregul downregul mani gene found relat glutathion metabol transport glutathion metabol pathway p clarkii thus activ cr exposur detoxifi maintain bodi function valid deg quantit real time pcr confirm chang gene express thus studi provid data support glutathion focus respons p clarkii exposur heavi metal | D003400;D031663 | T204;T002 |
34,673,410 | role nramp transport gene spirodela polyrhiza cadmium accumul pollut cd caus sever impact environ damag live organ uptaken environ natur resist associ macrophag protein nramp plant howev ion absorpt function nramp transport gene spirodela polyrhiza report studi spnramp spnramp spnramp polyrhiza clone function analyz polyrhiza yeast growth paramet physicochem indic wild type transgen line measur cd stress result reveal spnramp spnramp spnramp identifi plasma membran local transport role transport cd verifi yeast polyrhiza spnramp overexpress signific increas content cd fe mn fresh weight spnramp overexpress increas mn cd spnramp overexpress increas fe mn concentr result indic spnramp spnramp spnramp differ prefer ion absorpt two polyrhiza transgen line oe oe obtain one oe show stronger accumul abil one oe exhibit toler capac cd studi provid new insight function spnramp spnramp spnramp obtain import enrich line oe manipul cd accumul phytoremedi ecolog safeti | D029064;D027682 | T116;T002;T123 |
34,673,409 | urban fine particul air pollut exposur promot atherosclerosi apolipoprotein e defici mice activ perivascular adipos tissu inflamm via wntaror signal pathway urban fine particul matter pm deleteri risk factor ambient air recogn exacerb atherosclerosi perivascular adipos tissu pvat secret larg number inflammatori cytokin play crucial role pathogen microenviron atherogenesi howev lack knowledg role pvat inflamm genesi pm relat atherosclerosi aim research probe latent link pm exposur pvat inflamm discov under mechan pm trigger atherosclerosi pathogenesi apolipoprotein e defici apo mice expos real world atmospher pm filter clean air three month wnta inhibitor box ror inhibitor arrestin appli verifi possibl mechan notic averag daili pm mass concentr gm pm inhal might signific expedit deterior atherosclerosi increas protein mrna express mcp il tnf wnta ror pvat tissu upregul distribut il tnf mcp leptin histolog section pvat promot lipid deposit aorta elev plasma level leptin mcp il tnf ldl c tc tg howev decreas plasma level adiponectin hdl c downregul distribut adiponectin nevertheless effect caus pm exposur dramat diminish administr box arrestin research illumin pvat inflamm involv pm induc atherosclerosi process well lipid deposit close associ activ wntaror signal pathway | D000397;D050197 | T080;T069;T047;T046 |
34,673,408 | gestat arsenic exposur induc anxieti like behavior adult offspr reduc dna hydroxymethyl develop brain sever studi found reduct hydroxymethylcytosin hmc marker dna hydroxymethyl high enrich develop brain associ anxieti like behavior studi aim investig whether gestat arsenic exposur induc anxieti like behavior adult offspr reduc dna hydroxymethyl develop brain dam drank ultrapur water contain naaso mgl throughout pregnanc anxieti like behavior evalu develop brain hmc detect result show anxieti like behavior observ expos adult offspr addit hmc content reduc expos fetal brain despit differ tet tet tet express tet activ suppress expos fetal brain mechanist alpha ketoglutar kg cofactor tet dioxygenas reduc idh key enzymat gene mitochondri kg synthesi downregul expos fetal brain interest ascorb acid cofactor tet dioxygenas revers induc suppress tet activ moreov ascorb acid attenu induc reduct hmc fetal brain addit ascorb acid allevi induc anxieti like behavior adult offspr taken togeth result suggest gestat exposur induc anxieti like behavior adult offspr possibl part inhibit dna hydroxymethyl develop brain | D001151 | T131;T121;T196 |
34,673,407 | mir promot cadmium induc autophagi rat hepatocyt suppress rheb express cadmium environment pollut threaten health human anim current studi shown hepatotox damag induc cadmium close relat autophagi intrins mechan elucid microrna play regulatori role differ stage autophagi studi investig mechan microrna mir regul cadmium induc hepatotox rat hepatocyt brl cell vivo found cadmium exposur could caus liver injuri rat result decreas liver index increas alanin aminotransferas alt aspart aminotransferas ast alkalin phosphatas alp activ hepatocyt steatosi ultrastructur damag cadmium exposur also induc autophagi hepatocyt result increas express atg belin lcii increas number autophagosom addit cadmium exposur upregul mir express downregul rheb mrna express downregul level protein express rhebmtor signal pathway rat hepatocyt overexpress mir follow cadmium exposur upregul level autophagi brla cell wherea mir inhibit opposit effect addit mir negat regul rheb dual luciferas report assay verifi negat regulatori effect mir rheb target knockdown rheb downregul cadmium induc autophagi therefor rhebmtor signal negat regul autophagi present studi demonstr mir promot cadmium induc autophagi rat hepatocyt suppress rheb express | D002104;D035683 | T131;T114;T196;T123 |
34,673,406 | soybean isoflavon protect sh syy neuron atrazin induc toxic activ mitophagi stimul bexbnipnix pathway atrazin atr wide use herbicid induc degener dopaminerg daergic neuron substantia nigra result parkinson diseas like syndrom despit high risk environment exposur studi investig strategi prevent atr neurotox previous studi demonstr atr impair mitochondri function lead metabol failur cell maintain mitochondri qualiti select autophag elimin term mitophagi soybean isoflavon si possess multipl benefici bioactiv includ preserv mitochondria function hypothes si protect neuron atr toxic promot mitophagi pretreat sh syy neuron si prevent atr induc metabol failur cytotox assess intracellular atp na k atpas activ mitochondri membran potenti cell viabil assay neuroprotect efficaci si superior major individu compon genistein daidzein glycitein ultrastructur analys reveal atr induc mitochondri damag si promot sequestr damag mitochondria autophag vesicl soybean isoflavon also induc mitophagi evidenc upregul express bnipnix bex lc ii co treatment mitophagi inhibitor mdivi block si mediat neuroprotect prevent si revers atr induc bex downregul furthermor bex knockdown inhibit si induc activ bnipnix pathway mitophagi neuroprotect find suggest si protect atr induc mitochondri dysfunct neurotox activ bexbnipnix pathway | D001280;D007529;D063306 | T043;T131;T121;T109 |
34,673,405 | effect compost deriv humic acid bio dechlorin pentachlorophenol high iron content paddi soil pentachlorophenol pcp common residu organ pollut paddi soil harm effect soil ecosystem confirm humic acid ha could act electron shuttl promot reduct dechlorin pcp anaerob condit humic like substanc produc compost kitchen wast abl facilit reduct dechlorin pcp fe iii oxid reduct iron reduc bacteria howev effect compost deriv reduct dechlorin pcp paddi soil system high iron content fulli confirm characterist differ stage compost bio dechlorin pcp still unclear function compon compost deriv respons reduct dechlorin pcp differ stage compost also need investig studi conduct seri experi guangdong paddi soil system high iron content mg kg investig reduct dechlorin pcp ha earli middl later stage food wast compost result show middl late stage compost deriv promot reduct dechlorin pcp paddi system opposit earli stage signific differ also present compon differ stage compost earli stage compost deriv contain numer easi degrad compon would inhibit dechlorin pcp chang microbi metabol paddi soil compost deriv middl compost stage show best reduct dechlorin effect pcp reason might compost deriv middl compost stage could act electron donor transfer electron transfer capac etc middl stage compost deriv signific higher earli later compost stage compar natur soil system compost deriv contain chlorin product lower toxic pcp degrad result main contribut detoxif miner pcp soil find clarifi effect compost deriv pcp bio dechlorin paddi soil high iron content identifi optim phase compost deriv ha provid theoret basi util kitchen wast compost resourc ha | D000076282;D010416;D012037;D012989 | T057;T109;T167;T131;T068 |
34,673,404 | direct inject amblyomma americanum tick cytauxzoon feli cytauxzoon feli tick born hemoprotozoan parasit caus life threaten diseas domest cat unit state current platform c feli research limit natur experiment infect domest cat studi aim develop altern model infect amblyomma americanum tick c feli via direct inject amblyomma americanum adult inject c feli infect felin erythrocyt two rout direct digest tract anal pore ia inject percutan tick hemocoel ih inject rnascop situ hybrid ish use visual parasit within tick differ time point inject four month inject tick divid infest group base inject method inoculum type fed nave cat assess tick abil transmit c feli prior transmiss challeng select tick infest group test c feli rna via revers transcript pcr rt pcr ia ih inject tick ish signal observ tick week inject number hybrid signal notabl decreas time signal detect month inject prior transmiss challeng sampl tick posit c feli rna via rt pcr major inject tick success attach fed replet cat transmiss challeng none cat becam infect c feli result suggest inject c feli remain aliv tick unabl progress infect sporozoit inject unclear infect techniqu success close relat tick born hemoprotozoa c feli outcom may associ uncharacter differ c feli life cycl lack feed molt model absenc gametocyt inoculum nonetheless studi demonstr potenti use tick altern model studi c feli futur improv tick model c feli consid tick speci inject model util infect method close emul natur infect process | D002371;D045991;D026863;D011529;D013987 | T204;T015;T047 |
34,673,403 | small rna express pattern semin plasma exosom isol semen contain spermatozoa cytoplasm droplet versus regular exosom boar semen multipl physiolog pathway control exosom exosom may found semin plasma carri function molecul sperm microrna mirna sperm cytoplasm droplet cds remnant cytoplasm migrat morpholog characterist epididym matur howev mirna express pattern semin plasma exosom found semen contain spermatozoa cds versus regular exosom boar semen examin studi semin plasma exosom isol semen contain spermatozoa cds mirna express profil analyz total known new mirna identifi sixteen mirna signific differenti express mirna ssc mir ssc mir p ssc mir ssc mir p ssc mir p ssc mir ssc mir p ssc mir c ssc mir ssc mir ssc mir p ssc mir p ssc mir p signific upregul wherea three mirna ssc mir ssc mir p ssc mir p signific downregul go kegg pathway analys show target gene enrich function metabol process reproduct process proteasom ubiquitin mediat proteolysi oxid phosphoryl therefor semin plasma exosom predict play key role regul sperm cds | D001826;D055354;D035683 | T026;T031;T114;T123 |
34,673,402 | safeti recommend vaccin children inborn error metabol inborn error metabol iem genet disord due defect metabol pathway incid disord variabl depend respect popul disord urea cycl disord ucd organ aciduria pose high risk metabol crisi culmin life threaten event especi infect thus vaccin may play crucial role prevent howev differ trigger decompens includ notion vaccin activ fever malais addit mani iem includ immunodefici place patient increas risk infecti diseas possibl weaker respons immun sinc metabol crise vaccin regimen intersect first year life question whether vaccin child occupi parent medic staff mani metabol expert hesit vaccin iem patient disregard higher risk direct infect paper summar publish data regard safeti recommend vaccin iem patient refer risk decompens immunogen compon | D008661;D056806 | T047;T019 |
34,673,401 | health relat qualiti life children adolesc tuber sclerosi complex caregiv multicentr cohort studi germani studi aim measur health relat qualiti life hrqol children adolesc tuber sclerosi complex tsc qualiti life qol depress symptom among caregiv | D011788;D014402 | T191;T078 |
34,673,400 | ecolog impact antibiot bioremedi perform construct wetland microbi plant dynam potenti antibiot resist gene hotspot construct wetland cws natur base solut treat domest livestock wastewat may contain residu antibiot concentr antibiot may exert select pressur wetland microb therebi increas global antibiot resist problem review critic examin chemodynam antibiot antibiot resist gene arg cws antibiot affect biogeochem cycl function microbi communiti cws direct disrupt remov effici total nitrogen total phosphorus chemic oxygen demand respect sinc chang microbi function structur link emerg propag antibiot resist antibiot could advers affect microbi divers cws cyanobacteria communiti seem particular vulner proteobacteria could resist persist antibiot contamin wetland antibiot trigger excit respons plant increas root activ exud microb plant substrat play crucial role antibiot remov high remov effici exhibit triclosan enrofloxacin metronidazol tetracyclin chlortetracyclin levofloxacin sulfamethoxazol cws review show cws exhibit high antibiot remov capac absolut abund arg increas suggest cws potenti hotspot arg futur research focus specif bacteri respons impact microbi interact | D014874;D053833 | T131;T070;T083 |
34,673,399 | feasibl studi metal sulfid fes mns simultan denitrif chromat reduct metal sulfid base biolog process consid promis biotechnolog next generat wastewat treatment howev clear simultan bio reduct nitrat chromat achiev process studi aim evalu feasibl metal sulfid fes mns simultan denitrif chromat reduct autotroph denitrifi column bioreactor result show simultan reduct nitrat chromat achiev use metal sulfid fes mns electron donor sulfat sole solubl end product apart sulfur element metal sulfid fe ii mn ii also involv nitrat chromat reduct indic format oxid state compound microbi communiti shd thiobacillus predomin bacteria might play import role simultan denitrif chromat reduct compar fes mns show higher perform nitrat chromat remov could also reduc toxic inhibit chromat nitrat reduct accord result xrd xps well lower sulfat product fes system fes might cover easili hydroxid due bio oxid limit mass transfer effici bio avail fes find studi offer insight develop promis approach treatment toxic hazard compound use metal sulfid | D002840;D058440 | T197;T067 |
34,673,398 | simul impact volatil atmospher concentr pesticid chemistri transport model chimer method develop applic metolachlor folpet modul simul volatil pesticid soil plant implement air qualiti model chimer order simul spatiotempor distribut pesticid atmospher concentr pesticid applic spatial distribut accord quantiti pesticid sold per municip franc record french bnvd databas tempor distribut accord applic period determin enquiri model appli metolachlor folpet first stage studi pesticid emiss simul chimer voltair model compar second stage measur concentr metolachlor folpet mid april end june compar simul result french paca southeastern region franc scale model reproduc spatial distribut metolachlor concentr spatial correl franc bias rang station applic period simul folpet concentr remain challeng lack correl model result measur could possibl due lack precis tempor applic | D010575 | T131 |
34,673,397 | fluoresc activ droplet sort pet degrad microorgan enzym decompos synthet plastic polyethylen terephthal pet urgent need still bottleneck remain due lack techniqu detect sort environment microorgan vast divers abund develop fluoresc activ droplet sort fad pipelin high throughput screen pet degrad microorgan enzym petas pipelin compris three step generat incub droplet encapsul singl cell picoinject fluorescein dibenzo fdbz fluorogen probe screen droplet obtain pet degrad cell character critic factor associ method includ specif sensit discrimin petas enzym optim perform compat environment sampl system use screen wastewat sampl pet textil mill success obtain pet degrad speci nine differ genera moreov two putat petas isol kineococcus endophyticus un staphylococcus epidermidi un c genet deriv heterolog express preliminarili valid pet degrad activ specul fad pipelin wide adopt discov new plastic degrad microorgan enzym various environ may util direct evolut degrad enzym use synthet biolog | D006867;D011093 | T116;T126;T109;T122 |
34,673,396 | non thermal plasma irradi polyaluminum chlorid heterogen adsorpt enhanc cs sr binari system natur ecosystem continu deterior decad leakag cs sr isotop explor new materi techniqu effici treatment radioact wastewat critic import studi dielectr barrier discharg dbd configur construct oper non thermal plasma ntp ntp incorpor synthesi polyaluminum chlorid pac two differ procedur intensifi synthesi pac ntp pac enhanc remov cs sr wastewat employ ntp two procedur signific chang physicochem characterist pac materi facilit adsorpt applic ntp pac treatment cs sr differ molecular morpholog adsorpt characterist confirm ntp pac materi heterogen adsorpt ntp pac appropri fit pseudo first order kinet model elovich model physisorpt chemisorpt reaction mechan ensur heterogen adsorpt ntp pac materi toward cs sr guarante excel adsorpt perform ntp pac materi compar pac electron collis caus ntp alum pulp creat high reactiv growth precursor intensifi nucleat hydrolysi polymer pac employ ntp explicit broaden reaction pathway pac cation contamin aqueous environ expand applic area pac materi environment sustain | D058626 | T104 |
34,673,395 | selenium migrat mechan wet fgd slurri experiment dft analysi selenium se one hazard trace element emit coal fire power plant se migrat behavior wet flue gas desulfur fgd slurri still unclear speci se fgd gypsum remain controversi research bubbl experi use simul slurri withwithout gypsum crystal process conduct experiment result indic pure gypsum poor capabl captur se compon selenit could trap gypsum crystal growth stage furthermor dft calcul conduct provid microscop inform se adsorpt substitut characterist gypsum crystal process research find studi could help understand mechan se migrat process fgd slurri facilit develop effect se emiss control technolog futur | D012643;D014131 | T121;T196;T123 |
34,673,394 | pyrolysi wast oil product biofuel critic review applic wast oil pyrolysi feedstock produc high grade biofuel receiv extens attent diversifi energi suppli address environment challeng caus wast oil treatment fossil fuel combust wast oil optim raw materi produc biofuel due high hydrogen volatil matter content howev tradit dispos method gasif transesterif hydrotr solvent extract membran technolog difficult achiev satisfactori effect owe shortcom like enorm energi demand long process time high oper cost hazard materi pollut usag clean safe pyrolysi technolog break current predica bio oil produc convent pyrolysi wast oil high yield hhv great potenti replac fossil fuel contain high acid valu mg kohg nevertheless applic cao naoh signific decreas acid valu bio oil close zero addit addit coexist bifunct catalyst sba mgo zn particular simultan reduc acid valu posit influenc yield qualiti bio oil moreov co pyrolysi plastic wast effect save energi time improv bio oil yield qualiti consequ paper present critic comprehens review product biofuel use convent advanc pyrolysi wast oil | D056804;D000077319 | T070;T109 |
34,673,393 | fate pah treat wastewat reus irrig water environment risk water soil ryegrass multimedia system main aim studi determin fate bio metabol environment risk low ring high ring polycycl aromat hydrocarbon pah water soil ryegrass multi media system long term irrig condit micro pollut treat wastewat field experi carri simul garden irrig use treat wastewat contain typic repres low ring naphthalen nap high ring benzo pyren bap result show bap vertic attenu rate adsorpt accumul rate time higher nap respect adsorpt biodegrad rhizospher effect respons respect attenu bap nap major metabol pathway nap bap hydroxyl ring open cleavag decarboxyl metabol chain bap longer nap due ring cleav reaction pseudomona mycobacterium sphingomona function microorgan pah degrad capac posit correl pah degrad particular rhizospher ten year irrig treat wastewat predict environment risk reveal potenti risk thus result feasibl studi demonstr use treat wastewat garden irrig relat safe effect strategi | D008129;D011084;D012989 | T131;T002;T109 |
34,673,392 | fe mn dope powder activ carbon pellet ozon catalyst cost effect phenol wastewat treatment mechan studi phenol product elimin novel bimetal dope pac fe mnpac pellet prepar facil sol gel method use ozon catalyst phenol wastewat pww treatment adopt fe mnpac pellet microbubbl ozon enhanc h chemic oxygen demand cod phenol remov pww respect ozon dosag mgl gl fe mnpac pellet exhibit ozon convers comparison microbubbl ozon process fe mnpac induc microbubbl catalyt ozon process promot ozon decomposit rate time term oh product fe mnpac pellet enhanc oh exposur time r ct valu r ct kinet model also suggest fe mnpac pellet obtain higher kinet rate constant initi promot oh generat usag fe mnpac pellet microbubbl ozon phenol wastewat treatment also reduc total ozon consumpt fe mnpac induc microbubbl catalyt ozon process ratio ozon consumpt cod remov cod fe mnpac pellet character x ray photoelectron spectroscopi xps fourier transform infrar ft ir x ray powder diffract xrd analysi reveal success dope fe mn pac substrat larger number carbon oxygenhydroxyl surfac group play key role ozon decomposit oh product | D010126;D014874 | T131;T103 |
34,673,391 | enhanc photocatalyt effici direct photoexcit electron transfer pollut adsorb surfac valenc band biobr modifi graphit c herein novel biobr photocatalyst partial surfac modif graphit c biobr c g synthes hydrotherm method hydrotherm carbon carbon htcc slow releas carbon sourc character experiment theoret method biobr c g exhibit excel visibl light photocatalyt perform toward various refractori pollut bisphenol ibuprofen ciprofloxacin dichlorophenoxyacet acid diphenhydramin character result demonstr strong molecular orbit interact occur graphit c biobr result format new surfac valenc band graphit c promot oxid pollut surfac hole also reduc recombin carrier bulk phase transfer process therebi increas number photogener carrier intrigu analyt result degrad intermedi character techniqu demonstr pollut adsorb graphit c biobr c g direct excit light irradi react along organ radic degrad pathway addit pollut degrad hole ho | D004785 | T131 |
34,673,390 | rhizobium rhizogen mediat root prolifer cdzn hyperaccumul sedum alfredii effect plant growth promot root exud metal uptak effici studi rhizobium rhizogen mediat root prolifer system sedum alfredii establish twenti strain r rhizogen screen root prolifer signific differ p observ plant morpholog charact influenc differ bacteri strain highest root fresh weight gplant observ strain furthermor signific differ p observ chemic composit organ acid tartar acid ta succin acid sa malic acid citric acid ca oxal acid oa ph total nitrogen tn total organ carbon toc solubl sugar root exud differ r rhizogen mediat root furthermor seri hydropon experi conduct vari concentr cd zn assess phytoextract effici prolifer root rhizobium sever plant prolifer root show enhanc growth improv metal extract effici five strain lba k msu cc identifi potenti strain root prolifer sedum alfredii r rhizogen strain improv cdzn phytoextract exogen product phytochem promot root prolifer improv shoot biomass lower oxid damag enhanc phytoextract effici alfredii therefor select potenti microbi partner alfredii develop extens root system better growth enhanc phytoremedi potenti result suggest r rhizogen mediat root prolifer system use optim metal extract contamin soil | D031963;D012989 | T131;T002 |
34,673,389 | bimetal oxid complex meet fenton like process heterogen fenton like reaction advanc oxid process wide recogn effici remov recalcitr organ contamin recent year construct effici reusabl heterogen fenton like catalyst extens investig recent use bimetal oxid complex catalyst fenton like reaction attract intens attent due high catalyt perform excel stabil wide ph rang articl fundament mechan fenton like reaction briefli introduc import report bimetal oxid complex classifi detail main divid fe base fe free bimetal catalyst focus depth perform respect applic fenton like reaction special consider given respect contribut synergist mechan two metal catalyst overal conclud synergist effect two metal bimetal catalyst boost util hydrogen peroxid provid adequ access activ site benefici improv catalyt perform final current challeng field propos review expect provid help applic bimetal oxid complex | D007501;D010087 | T197;T121;T196;T123 |
34,673,388 | perceiv profession compet spiritu care predict role spiritu intellig iranian nurs student aim studi identifi relationship perceiv compet spiritu care spiritu intellig among nurs student | D004508;D026443;D013338 | T065;T097;T061;T067;T058 |
34,673,387 | turkish version patient safeti compet self evalu tool valid reliabl studi test valid reliabl patient safeti compet self evalu tool turkish develop evalu patient safeti compet nurs student | D061214;D013338 | T058;T097 |
34,673,386 | associ residenti instabl individu area level futur psychosi adolesc clinic high risk north american prodrom longitudin studi napl consortium accumul evid support associ residenti instabl increas risk psychosi associ residenti instabl convers psychosi among adolesc clinic high risk chr unclear studi determin whether individu level area level residenti instabl interact associ convers psychosi within two year | D062706;D011618 | T048;T184 |
34,673,385 | metastasectomi versus radiat secondari site stage iv breast cancer analysi nation cancer registri locoregion therapi primari secondari site breast cancer may associ improv surviv compar system therapi alon explor sociodemograph clinicopatholog factor associ use radiat versus surgic resect metastat site metastasectomi patient de novo stage iv breast cancer follow associ overal surviv | D001943;D059146 | T191;T061 |
34,673,384 | enhanc gene regulatori network infer hub base data integr one main research topic comput biolog gene regulatori network grn reconstruct refer infer relationship gene involv regul cell condit respons intern extern stimuli end comput method use transcript gene express data reconstruct gene regulatori network recent studi suggest gene express data must integr type data obtain accur model predict real relationship gene studi diffus base method enhanc integr biolog data network type besid structur prior knowledg random walk restart algorithm rwr emphasi hub node execut separ network joint optim low dimension featur vector network node diffus compon analysi next featur vector use infer gene regulatori network fourteen central measur studi detect hub node use rwr algorithm best central measur greatest effect improv gene network infer select case studi saccharomyc cerevisia e coli network show use propos featur comparison gene express data alon result unit improv area receiv characterist oper auroc criteria across differ gene regulatori network infer method furthermor propos method appli esophag cancer data infer gene regulatori network propos framework substanti improv accuraci scalabl grn infer fuse featur best central measur detect use provid function insight gene protein various biolog applic moreov serv general framework network data structur data integr analysi problem various scientif disciplin includ biolog | D019295;D053263 | T091;T044 |
34,673,383 | childhood advers modul central autonom network compon cognit regul emot major depress disord borderlin person disord advers childhood experi ace lifelong effect emot behavior frequent borderlin person disord bpd major depress disord mdd central autonom network modul heart rate variabl hrv compris brain region mediat emot regul process howev remain unclear effect ace dynam relationship hrv disord studi effect ace brain hrv simultan regul psycholog stress bpd mdd healthi control hc particip underw cognit reapprais task fmri simultan ecg acquisit ace exposur associ increas activ salienc network compon patient mdd compar bpd cognit reapprais brain autonom coupl found bpd relat hc emot regul wherebi greater activ left anterior cingul medial superior frontal gyrus area coupl increas hrv result suggest ace exposur associ distinct activ salienc network region govern respons psycholog stress mdd compar bpd alter may constitut distinct neurobiolog mechan abnorm emot process regul relat ace mdd | D000076783;D001883;D003865 | T033;T048 |
34,673,382 | context awar driver model determin recommend speed blind intersect situat near miss event involv vulner road user lead serious accid safe care expert driver perform hazard anticipatori drive natur seek reduc uncertainti attempt fit current drive context pre exist categori alreadi develop predict happen studi target situat consist cyclist attempt road cross blind spot studi aim develop context awar driver model determin recommend drive speed blind intersect base analysi near miss incid databas includ data driver behavior road environment factor near miss first extract drive record data use manag tool provid databas second risk defin time margin driver perform evas action avoid crash quantifi extract data use safeti cushion time safeti cushion time observ result driver adjust vehicl veloc depend given road environ one key aspect develop context awar driver model categor extract near miss data two level base risk quantif low high risk event low high risk event regard result driver appropri adjust inabl failur adjust vehicl veloc depend given road environ respect third base multipl linear regress analysi low risk event dataset construct context awar driver model produc recommend vehicl speed depend given road environ road environ variabl determin stepwis regress identifi factor reduc increas vehicl veloc blind intersect incorpor model predictor furthermor quantit visual driver set baselin speed adjust increas decreas speed accord given road environ context fourth model valid demonstr coeffici determin r mean absolut error mae kmh averag fold cross valid final investig effect construct driver model safeti perform use dataset high risk event test data theoret construct driver model guid driver drive vehicl recommend speed thus convert half high risk event low risk event result indic context awar driver model feasibl use adjust approach speed blind intersect accord road environ factor | D000063;D001334 | T056;T037;T067 |
34,673,381 | chang share privat e scooter use brisban australia safeti implic share electr scooter e scooter scheme debut us citi spread mani citi worldwid rider inexperi inexperi road user interact e scooter may contribut injuri share e scooter came brisban australia novemb observ studi februari found high level non complianc regul rider share privat e scooter paper examin whether e scooter safeti improv time compar number behavior share privat e scooter rider follow observ studi conduct octob rider e scooter bicycl count six site inner citi brisban train observ four weekday type e scooter privat lime neuron helmet use gender age group ride locat time day presenc passeng record number share e scooter observ drop februari octob number privat e scooter increas result slight reduct total number e scooter correct helmet wear rate increas non signific share e scooter remain high rider privat e scooter februari octob percentag e scooter ridden road illeg central brisban remain rough share februari octob privat februari octob percentag children adolesc illeg ride share e scooter fell preval illeg behavior among share e scooter rider fell signific share e scooter rider preval illeg behavior rider remain lower chang reduct illeg behavior among share e scooter rider accompani tripl usag privat e scooter suggest e scooter safeti like improv | D000063;D006260 | T073;T037;T067 |
34,673,380 | comput model driver pre crash brake respons without road glanc parameter use real world crash near crash face immin collis threat human vehicl driver respond brake manner stereotyp yet modul complex way mani factor includ specif traffic situat past driver eye movement comput model captur phenomena would high appli valu exampl virtual vehicl safeti test method exist model either simplist suffici valid paper extend exist quantit driver model initi modul pre crash brake respons handl road glanc behavior result model fit time seri data real world naturalist rear end crash near crash stringent parameter model select procedur present base particl swarm optim maximum likelihood estim major contribut paper result first ever fit comput model human brake real near crash crash behavior data model select result also permit novel conclus regard behavior accid causat first result indic driver partial visual loom percept road glanc evid brake collect albeit slower pace driver look away forward roadway second result suggest import causat factor crash without road glanc may reduc respons visual loom possibl associ cognit driver state eg drowsi erron driver expect also demonstr model parameter less critic data near crash may also accur reproduc driver behavior high critic situat crash | D000063;D001334 | T056;T037;T067 |
34,673,378 | pt cis diaminocycloalkan cl analog exhibit hallmark typic immunogen cell death induc model cancer cell platinum drug belong prevail chemotherapeut use treatment cancer present howev search new anticanc metal base drug oper mechan distinct convent chemotherapeut activ furthermor demonstr cytotox chemotherapi immunotherapi may exert high synergist anticanc activ thus develop antitumor platinum metal base drug exhibit cytostat effect concurr elicit immunogen cell death icd shown promis cancer treatment notabl convent platinum drug oxaliplatin pt rr dach oxal dach diaminocyclohexan well known agent display cytostat immun respons moreov also demonstr even minor derivat unleav cycloalkyl moieti oxaliplatin might pronounc effect immunomodulatori activ investig replac rr diaminocyclohexan ring diaminocycloalkan alkan butan pentan hexan affect abil evok secret damag associ molecular pattern characterist icd model murin colorect carcinoma cell line ct result indic among investig pt cis diaminocycloalkan cl complex complex contain cyclobutyl moieti exhibit hallmark typic icd induc thus pt cis diaminocyclobutan cl may expand spectrum anticanc chemotherapeut capabl induc icd cancer cell might interest pre clinic develop | D000970;D015179;D056831;D000091369;D009374;D010984 | T191;T121;T109;T050;T104;T196 |
34,673,377 | effect integr object boundari region improv perform medic imag segment use two cascad network exist cnn base method object segment use region object alon label train network potenti use boundari annot radiologist use direct train thus propos framework two cascad network integr region boundari inform improv accuraci object segment | D007091;D014057 | T066;T060 |
34,673,374 | calreticulin function antimicrobi immun obscur puffer takifugu obscurus calreticulin crt high conserv multi function protein lectin like properti import immunolog activ studi crt homolog name tocrt clone character obscur puffer takifugu obscurus open read frame bp encod putat protein amino acid deduc amino acid sequenc tocrt consist three conserv structur domain n domain p domain c termin domain phylogenet tree tocrt form separ cluster three crts pufferfish speci takifugu rubrip takifugu flavidus takifugu bimaculatus mrna transcript tocrt ubiquit express examin tissu decreas order liver spleen kidney gill intestin heart vibrio harveyi edwardsiella tarda aeromona hydrophila stimul level tocrt mrna kidney spleen signific upregul compar control group recombin calreticulin domain tocrt rtocrt could bind three gram negat bacteria v harveyi e tarda hydrophila polysaccharid bacteri cell wall lipopolysaccharid peptidoglycan meanwhil rtocrt could agglutin differ kind microorgan exhibit antimicrobi activ result suggest obscurus tocrt could serv antimicrobi effector host immun respons invad microorgan | D007109 | T042 |
34,673,373 | interplay ferric uptak regul fur horizont acquir virul regul esrb coordin virul gene express edwardsiella piscicida edwardsiella piscicida mediat hemorrhag septicemia lead pathogen fish e piscicida invad colon macrophag use type iii vi secret system ttss control two compon system tcs esra esrb iron acquisit essenti e piscicida pathogenesi coordin iron tcs signal modul bacteri virul well understood show iron uptak system co regul ferric uptak regul fur e piscicida fur bound gene harbor conserv fur box global control express gene includ encod iron uptak system ttss icc camp phosphodiesteras repress biofilm format addit fur complex iron bound esrb promot repress express ultim attenu virul convers esrb activ express ttss iron uptak system mitig shortag intracellular iron iron scarciti furthermor esrb direct bound activ fur promot lead fur ferrous ion depend esrb repress presenc iron final fur esrb interplay essenti bacteri fit vivo infect surviv seawat environ collect highlight mechan underli reciproc regulatori network iron homeostasi virul system e piscicida | D001426;D020594;D015964;D012097;D014774 | T116;T007;T045;T123;T032;T038 |
34,673,372 | molecular dock sar cov spike epitop sequenc identifi heterodimer peptid protein complex format human zo tlr brain specif glial protein sar cov infect caus sever respiratori tract ill lead asphyxia death onset infect associ loss smell blur vision headach bronchopulmonari symptom clinic observ neurolog abnorm lead us address question virus enter brain under mechan brain infect work hypothesi sar cov spike epitop modifi blood brain barrier infect glial cell induc brain inflamm genet divers human popul hypothesi test determin bind interact abil virus spike epitop peptid mlys alaglu human toll like receptor tlr brain target vascular cell adhes molecul vcam protein zonula occluden zo glial cell specif protein ndrg apo sb molecular dynam experi perform root mean squar deviat rmsd valu determin interact spike peptid select protein observ demonstr format heterodimer complex epitop peptid select protein structur viral epitop abil bind hla drb allel thus found immunogen natur observ altogeth suggest entri spike protein epitop human brain caus inflamm | D000086382;D000086402 | T047;T005;T067 |
34,673,371 | model sar cov associ thrombocytopenia associ hemophagocyt histiocyt subset covid patient experienc secondari immun thrombocytopenia also call immun thrombocytopen purpura itp secondari hemophagocyt lymphohistiocytosi hlh pathogenesi sar cov associ thrombocytopenia unknown rare case vaccin induc prothrombot immun thrombocytopenia vipit occur associ covid vaccin covid vipit associ autoantibodi target platelet factor pf covid adenovirus vaccin herein four model hemophagocyt histocyt contribut etiolog thrombocytopenia associ sar cov propos one model propos potenti involv hemophagocyt histocyt target platelet bound autoantibodi consist observ pf autoantibodi covid vipit | D000086382;D013921 | T047;T067 |
34,673,370 | systemat compil set quantit metric describ spatial characterist radiotherapi dose distribut aid treatment plan mani quantit metric propos literatur character spatial dose properti aim studi work toward much need consensus radiotherapi communiti metric use compar characterist metric provid systemat select set metric comprehens quantifi properti spatial dose distribut | D011880;D050397 | T061 |
34,673,366 | role medic school prestig locat neurosurgeri resid placement analysi data remain gap literatur analyz categor variabl may affect high competit neurosurgeri resid applic process md senior unit state aim improv understand impact medic school prestig geograph locat candidaci neurosurgeri resid | D007396;D012577 | T097;T065;T093;T073 |
34,673,365 | entangl affect space evid pandem healthcar analysi australian healthcar worker experi covid covid pandem continu highlight global interconnected schism across place context peopl countri australia securitis border respons global spread diseas flow inform collect affect continu permeat boundari draw interview australian healthcar worker examin experi pandem shape affect evid travel across time space analysi point limit global health crisi respons focus sole materi risk spatial separ institut respons must suggest also consid affect discurs dimens health relat risk environ | D000086382;D058873 | T047;T067 |
34,673,363 | biomechan studi proxim humer fractur fixat lock plate medial support screw vs lock plate intramedullari fibular graft purpos studi evalu biomechan properti two differ fixat construct varus collaps proxim humerus fractur lock plate medial support screw lock plate intramedullari fibular graft | D005594;D012784 | T037;T061 |
34,673,362 | flavor cigar avail oakland partial ban report continu avail flavor cigar base analysi discard cigar wrapper collect februari partial flavor ban oakland ca | D005421;D062789 | T131;T120;T073;T109 |
34,673,361 | relationship parent psycholog control problemat smartphon use earli chines adolesc repeat measur studi two time point current studi examin bidirect relationship parent psycholog control problemat smartphon use psu earli chines adolesc use two time point repeat measur studi explor role psycholog secur insomnia relationship parent psycholog control subsequ psu earli adolesc sampl consist fourth fifth grade student male age age sd particip two measur complet questionnair parent psycholog control psu psycholog secur insomnia result indic autoregress cross lag model show reciproc relationship parent psycholog control psu sever earli adolesc psycholog secur insomnia mediat link parent psycholog control subsequ psu sever psycholog secur insomnia play serial mediat role parent psycholog control subsequ psu sever find indic reduc parent psycholog control boost psycholog secur allevi insomnia symptom adolesc conduc decreas psu sever earli adolesc | D000068997;D013334 | T098;T073;T081 |
34,673,360 | ongo tobacco use women experi homeless unstabl hous prospect studi inform tobacco cessat intervent polici tobacco use common peopl experi homeless howev despit biolog differ use sex lower quit rate women research homeless unstabl hous huh women spars identifi correl use specif popul goal inform tobacco cessat program tailor huh women | D006703;D020340 | T095;T033;T098;T055 |
34,673,358 | influenc crystallin phase transform induc airborn particl abras low temperatur degrad mechan properti dental zirconia ceram stabil mol yttria monolith dental prosthes fabric mol yttria stabil zirconia yz develop improv transluc convent mol yttria stabil zirconia studi aim evalu influenc airborn particl abras apa low temperatur degrad ltd mechan properti yz associ crystallin phase transform total disc shape specimen two brand yz lava esthet katana utml prepar specimen divid four group n group control ii apa iii ltd iv apa ltd group apa perform alumina particl ltd induc autoclav c h biaxial flexur strength specimen assess use piston three ball test accord iso vicker hard determin use microhard tester crystallin phase analyz rietveld refin x ray diffract pattern apa signific increas flexur strength lava esthet specimen wherea ltd hard affect strength materi apa apa ltd signific increas vicker hard materi accord rietveld analysi pseudocub phase predomin materi ie mass mass lava esthet katana utml specimen respect apa induc rhombohedr phase approxim mass materi ltd induc monoclin phase mass lava esthet specimen mass katana utml specimen apa ltd weak affect amount rhombohedr phase slight increas amount monoclin phase find suggest apa may improv mechan properti yz particular hard via generat rhombohedr phase contrast influenc ltd mechan microstructur properti yz limit | D002516;D015019 | T196;T073 |
34,673,357 | quasispeci bhk cell deriv virul tembusu virus strain contain three group variant distinct virul phenotyp previous studi result isol low virul plaqu purifi variant third passag p bhk cell tembusu virus tmuv isol suggest presenc viral quasispeci p cultur confirm notion fourth passag virus p prepar infect bhk cell p isol variant isol plaqu purifi virus compar genom sequenc analysi identifi six virus genet differ variant harbor total eight amino acid differ envelop ns ns ns protein test day old pekin duck model p caus mortal belong high virul tmuv strain six genet differ variant two present high virul one exhibit moder virul three display low virul caus mortal respect result demonstr p contain least three group variant distinct virul phenotyp analysi link eight residu virul six variant identifi ns protein residu ns protein residu andor novel determin tmuv virul analysi also provid new clue futur studi molecular basi tmuv virul term genet interact differ protein overal studi provid direct evid suggest tmuv exist vitro cultur virul isol quasispeci may enhanc understand molecular mechan tmuv virul | D005416;D018177;D011201 | T047;T005 |
34,673,356 | prefer qualiti australian general public willing pay home residenti age care australia mani countri intern age care servic provid older peopl home residenti care facil major servic fund feder govern use taxpay contribut general public howev monetari valu australian place age care servic factor predict valu examin therefor sought determin general public willing pay wtp age care servic examin factor influenc wtp cross section conting valuat survey administ nation repres cohort australian septemb octob general popul age year respond ask indic wtp valu satisfactori high qualiti age care servic provid futur two part regress model use explain factor explain variat wtp total respond will pay access satisfactori high qualiti home care counterpart figur residenti care averag respond will pay per week receiv satisfactori qualiti high qualiti home care per week satisfactori qualiti high qualiti residenti care respond will pay addit per week averag access high qualiti age care higher wtp valu general associ younger male recent experi age care close famili member access age care abil pay result suggest general public support payment individu co contribut access age care servic futur | D005190;D044469 | T079;T098;T099;T054;T062 |
34,673,355 | inform govern public privat partnership uk obes polici collabor calori reduct reduc effect collabor govern non state actor emerg domin mode polici make address wide rang public global health issu particular via public privat partnership multi stakehold platform despit paradigmat status contemporari health govern polit claim promis partnership approach effect state regul receiv limit attent studi address gap trace negoti calori reduct pledg within public health respons deal public privat partnership uk depart health food industri civil societi organis focus obes polici demonstr polit claim make depart health public privat partnership effect substitut legisl contrast protract conflictu negoti food industri busi associ employ erv goffman distinct frontstag backstag interact concept inform govern studi trace shift inform back stage govern mechan cope acut tension econom interest nutrit polici goal studi illustr shift back stage substant public health implic privileg commerci sector perspect marginalis civil societi particip inform serv refram calori reduct industri focus person respons lifestyl behaviour process reduc effect result suggest partnership multi stakehold approach wide promot legitim tool health govern visibl tension commerci sector public health interest challeng polit claim public privat collabor consensus orient effect inform govern use cope mechan manag tension public health commerci sector interest may symptomat wider dysfunct conflict interest partnership approach suggest may limit scope effect polici innov commerci sector actor perceiv core interest threaten | D006076;D055818 | T092;T064 |
34,673,354 | predict childhood lead exposur aggreg level use machin learn childhood lead exposur affect children year old us howev state recommend regular univers blood screen sever studi report use predict model estim lead exposur individu children albeit limit success lead exposur vari great among individu individu data easili access model train one locat alway perform well anoth report novel approach use machin learn accur predict elev blood lead level blls larg group children use aggreg data end use public avail zip code citytown bll data state new york n exclud new york citi massachusett n respect five machin learn model use predict childhood lead exposur use socioeconom hous water qualiti predict featur best perform model random forest fold cross valid roc auc score massachusett new york dataset respect model test new york citi data result compar measur blls borough level model yield predict excel agreement measur data citi level predict elev bll rate children new york citi close measur valu predict model one present potenti help identifi geograph hotspot signific larg occurr elev lead blood level children limit resourc may deploy risk | D007854;D007855 | T037;T131;T196 |
34,673,353 | identifi psychosoci determin water sanit hygien wash behavior develop evid base babi wash intervent reduc program diarrheal diseas remain lead caus child mortal global democrat republ congo drc year estim million episod diarrhea children five year age reduc enteropathi diarrhea undernutrit contamin environ reduc program seek develop theori driven evid base approach reduc diarrheal diseas among young children reduc prospect cohort studi walungu territori eastern drc took guidanc risk attitud norm abil self regul model integr behavior model water sanit hygien wash behavior chang theori identifi psychosoci factor associ wash behavior psychosoci factor measur among caregiv baselin caregiv respons child mouth dirti fomit handwash soap assess hour structur observ month follow caregiv agre child could becom sick put dirt mouth perceiv suscept caregiv agre could prevent child play dirti thing outsid self efficaci signific like stop child mouth dirti fomit higher perceiv suscept self efficaci disgust lower dirti reactiv associ higher handwash soap behavior studi took theori driven evid base approach identifi psychosoci factor target intervent develop find studi inform develop reduc babi wash modul deliv million peopl eastern drc | D012499;D014867 | T121;T090;T197 |
34,673,352 | dfttd dft studi deciph fluorid induc ring open process spiropyran dfttd dft method use determin fluorid anion sens mechan bis tert butyldimethylsilyloxi spiro benzo f chromeneffuoren abbrevi sp descript ring open ground state sp molecul isomer open form present reveal studi ground state sp stabl form contrast isom obtain open form initi ring open first fluorid ion attack nucleophil de silyl sp molecul attack fluorid ion may induc cspiro bond cleavag lead format two anion speci ie mc mc respect mc merocyanin mono de silyl process endogen follow ring open process furthermor orthogon geometri probe sp show ict charact wherea mc mc display ict charact owe format planar geometri along increas conjug fluoresc properti sp stabl isom open form ct mc mc predict theoret calcul emiss spectra uncov sp may show fluoresc could quench presenc fluorid anion | D001578;D005459 | T121;T109;T197 |
34,673,350 | understand correl suicid among usual pain discomfort canadian nation repres studi suicid ideat plan attempt elev among chronic pain howev popul base research limit studi primarili focus mechan associ increas rather decreas risk studi aim identifi correl associ increas decreas odd suicid among canadian usual paindiscomfort nation repres sampl | D059350;D013405 | T033;T047;T184 |
34,673,349 | cost effect dabrafenib schedul combin trametinib compar target therapi immunotherapi dacarbazin treatment unresect metastat melanoma brafv mutat colombia advanc melanoma account malign skin tumor approxim death attribut frequent mutat raf gene brafv associ wors prognosi object research evalu cost effect combin regimen dabrafenib plus trametinib compar target therapi immunotherapi dacarbazin treatment unresectablemetastat melanoma brafv mutat perspect colombian health system | D003606;D008545 | T191;T121;T109 |
34,673,348 | cardioprotect activ ethyl acet extract cinnamomi ramulus myocardi ischemiareperfus injuri rat via inhibit nlrp inflammasom activ pyroptosi nlrp inflammasom activ pyroptosi play import role myocardi ischemiareperfus injuri miri cinnamomi ramulus cr import folk medicin plant china deriv dri twig cinnamomum cassia l presl function warm tonifi heart yang tradit util treat cold blood cold amenorrhea phlegm edema arthralgia palpit well improv blood circul aqueous extract c ramulus report show signific therapeut potenti treat miri wherea previous investig china abroad report cardioprotect effect under mechan ethyl acet extract c ramulus creae bioactiv substanc cinnam acid ca trigger nlrp inflammasom activ subsequ pyroptosi | D015428;D000069292 | T043;T046 |
34,673,347 | salivari stress marker dog potenti marker acut stress along grow awar psycholog stress companion anim sever treatment becom avail address fear anxieti relat behavior dog detect vulner individu appli effect treatment reliabl evalu quantifi individu stress respons high demand develop measur variabl clinic applic investig need increas knowledg stress respons activ sympathet adren medullari sam hypothalam pituitari adren hpa axe immun system also activ although peripher cortisol level common use stress biomark primarili reflect hpa axi respons suffici reflect complex stress respons thus review primarili focus avail salivari biomark main reflect acut stress respons activ sam axi immun system dog hope review promot valid biomark dog aid develop futur studi evalu stress respons dog | D007030;D010913 | T022;T030 |
34,673,345 | rhinosinus without nasal polyp associ poorer health relat qualiti life copd rhinosinus without nasal polyp rssnp preval copd previous studi associ health relat qualiti life hrqol limit rssnp current recogn comorbid studi investig hrqol copd includ focus rssnp generic hrqol assess short form sf v questionnair compar copd control subject subgroup without rssnp associ rssnp copd versus generic hrqol assess multivari linear regress adjust age educ bodi mass index bmi diseas specif hrqol assess sinonas outcom test snot st georg respiratori questionnair sgrq copd assess test cat compar copd without rssnp associ rssnp assess multivari linear regress adjust age bmi fev predict rssnp associ poorer diseas specif hrqol higher snot total score point ci p psycholog subscal score point ci p sgrq symptom score point ci p cat score point ci p generic hrqol poorer copd patient control subject addit copd concomit rssnp associ poorer physic function general health vital physic compon summari rssnp copd associ poorer diseas specif hrqol clinic relev amen treatment recogn comorbid copd | D011788 | T078 |
34,673,342 | impact sonolyt ozon us degrad pesticid residu fresh veget fruit case studi faisalabad pakistan high pesticid residu fresh produc serious food safeti issu studi aim assess pesticid residu import veget fruit market faisalabad pakistan impact sonolyt ozon us treatment remov contamin short grower survey five regist most use pesticid acetamiprid carbendazim imidacloprid thiacloprid thiamethoxam identifi time optim trial us applic min okra show min treatment signific reduc three identifi chemic thiamethoxam imidacloprid thiacloprid without advers effect qualiti follow trial five fresh veget cauliflow chilli cucumb spinach tomato three fresh fruit grape guava peach collect three market faisalabad pool togeth uniform sampl veget fruit treat us min respect along control simpl tap wash determin impact pesticid degrad sampl process extract clean analysi use hplc uv vis isocrat mode data reveal presenc five mention chemic accumul mean residu gg test veget fruit respect subject us accumul chemic residu reduc gg treat veget fruit respect irrespect fresh produc mean residu thiamethoxam imidachloprid acetamiprid thiachloprid carbendazim reduc respect conclud sonolyt ozon treatment effect signific reduct pesticid residu veget fruit thus employ good food safeti practic culinari level reduc associ health hazard risk | D005638;D010573;D014675 | T131;T002;T168 |
34,673,340 | promis low intens ultrasound review sonosensit sonocatalyst ultrason activ bacteri kill antimicrobi resist becom one main public health issu modern societi ultrasonicantimicrobi treatment uat expect solv problem antimicrobi resist sinc ultrason treatment caus drug resist inactiv howev ultrason applic hinder due high energi cost cast light ultrasound tandem catalyst superior strategi bacteri inactiv present review focus uat assist continu develop organ sonosensit inorgan sonocatalyst applic nanomateri ultrason paramet chang low frequenc high power ultrasound high frequenc low power ultrasound review also present composit sonosensitizerssonocatalyst includ organ inorgan nanoparticl discuss ultrason activ mechan trigger catalyst base synergist effect ultrasound catalyst discuss import extracellular oxid intracellular oxid process bacteri inactiv overal uat combin catalyst appear effect treatment strategi success appli field medicin environment treatment food industri | D014465 | T070 |
34,673,339 | improv soak effici soybean sweep frequenc ultrasound assist paramet optim soybean soak import process bean product howev restrict long soak time herein soybean soak assist khz sweep frequenc ultrasound sfu shorten mechan soak time physicochem properti soybean analyz result show soak temperatur c ultrason power w soak time min optimum sfu assist paramet soak time reduc solubl protein content increas sfu base analysi acoust signal maximum voltag amplitud sfu increas increment oscil period cavit bubbl enlarg intercellular space size soybean cell membran permeabl enhanc unpleas beani flavor compound reduc therefor sfu could signific improv soak effici soybean provid theoret basi process enterpris soybean product | D013025 | T168 |
34,673,338 | ultrasound assist encapsul pandan pandanus amaryllifolius extract pandan pandanus amaryllifolius common use food ingredi southeast asia due delici flavor appet aroma bright green colour pandan plant uniqu found certain part world despit increas popular worldwid export market limit practic issu one main problem export pandan global market stabil transport due volatil activ constitu function properti pandan lost storag shipment studi explor abil ultrasound process technolog encapsul aromat pandan extract use lysozym chitosan shell materi khz ultrason use encapsul pandan extract w appli power two paramet ultrason probe tip core shell ratio vari control properti encapsul diamet probe tip use cm core shell volum ratio use size distribut stabil synthes microspher character understand explor possibl paramet variat impact size size distribut microspher found influenc paramet vari certain extent result show mean size microspher general smallest use cm probe tip lower core shell volum ratio largest use mm tip higher core shell volum ratio indic sonic paramet could fine tune achiev encapsul pandan extract storag export pandan encapsul microspher also found stabl storag least one month | D031673 | T002 |
34,673,337 | ultrasound regul flexibl protein materi fabric structur physic biolog properti ultrasound use biomateri field due high effici easi oper chemic treatment repeat high level control work demonstr ultrasound abl quick regul protein structur solut assembl stage obtain design properti protein base materi silk fibroin protein dissolv formic acid cacl solut system treat ultrasound vari time power alter variabl silk physic properti structur fine tune result investig fourier transform infrar spectroscopi ftir x ray diffract xrd scan electron microscopi sem differenti scan calorimetri dsc thermogravimetr analysi tga dynam mechan analysi dma gas permeabl water contact angl measur ultrason treatment aid interact calcium ion silk molecular chain lead increas amount intermolecular sheet helix uniqu structur chang caus silk film high insolubl water also induc hydrophil swell properti ultrasound regul silk materi also show higher thermal stabil better biocompat breathabl favor mechan strength flexibl also possibl tune enzymat degrad rate biolog respons cell growth prolifer protein materi chang ultrasound paramet studi provid uniqu physic non contact materi process method wide applic protein base biomateri | D012831 | T204 |
34,673,336 | evalu armedxpert softwar tool mixtureac mixtur interpret analyz mps str data massiv parallel sequenc mps technolog revolution studi genom variat transform dna analysi multipl field assay base mps must capabl discrimin variat introduc method ie artifact true polymorph pcr mps method target microsatellit marker artifact aris pcr mis incorpor pcr strand slippag stutter sequenc error reliabl detect artifact mix dna sampl signific challeng must address forens dna analysi armedxpert nichevis softwar tool mixtureac mixtur interpret analyz mps data categor sequenc read allel stutter non stutter artifact analyz autosom str loci mix sampl studi evalu armedxpert tool analysi str profil singl sourc mix sampl generat forenseq dna signatur prep kit verogen data eight experiment run sampl analyz one benchmark run two run test sensit pg dna input one run test artifici degrad sampl dna deriv bone blood card teeth well four run mix dna sampl vari ratio sex differ number contributor two six mixtureac stutter threshold initi set follow recommend verogen plus non stutter artifact threshold set allel read count benchmark run sampl plus two control contain total allel reveal artifact analyt threshold total artifact correct classifi mis classifi allel due exceed initi threshold set fals posit must resolv analyst time consum stutter threshold adjust base benchmark data sampl test result fals posit allel call revis set use analysi remain seven experiment run result show mixtureac accur classifi artifact allel laboratori specif threshold set use mixtur interpret tool appli two three person mixtur tool util analyz data mixtureac calcul base number allel locus read count possibl deconvolut outcom respect ratio | D016172;D059014 | T034;T059;T063 |
34,673,332 | activ kynurenin pathway predict mortal neurolog outcom cardiac arrest patient valid studi activ kynurenin pathway kp shown predict outcom cardiac arrest ca patient valid find swiss cohort | D006323;D007737 | T123;T116;T047;T046 |
34,673,331 | diagnost prognost predict model ventil associ pneumonia systemat review meta analysi predict model studi exist expert system improv diagnost accuraci ventil associ pneumonia vap aim systemat literatur review review summar state art predict model detect predict vap exhal breath patient report demograph clinic characterist | D053717 | T047 |
34,673,330 | lumefantrin attenu plasmodium falciparum artemisinin resist earli ring stage emerg artemisinin resist plasmodium falciparum malaria potenti becom global public health crisi southeast asia phenomenon clinic manifest form delay parasit clearanc follow artemisinin treatment reduc artemisinin suscept limit earli ring stage window suffici allow parasit surviv short half life artemisinin exposur screen known clinic implement antimalari drug perform identifi drug capabl enhanc kill activ artemisinin critic resist window result lumefantrin found increas kill activ artemisinin artemisinin resist clinic isol harbor cy kelch mutat isobologram analysi reveal synerg earli ring stage resist window lumefantrin combin artemeth artemisinin deriv clinic partner lumefantrin find suggest lumefantrin clinic explor partner drug artemisinin base combin therapi control emerg artemisinin resist | D000962;D037621;D016778 | T047;T121;T109 |
34,673,329 | character antimicrobi resist campylobact jejuni campylobact coli isol chicken pork preval antimicrobi resist amr profil investig campylobact jejuni campylobact coli chicken pork fukuoka japan amr profil compar c jejuni c coli strain isol total chicken pork sampl collect differ supermarket fukuoka campylobact spp isol convent method character pcr maldi tof ms among chicken sampl test posit c jejuni c coli respect three pork sampl posit c coli c jejuni posit sampl six strain c jejuni c coli isol respect antimicrobi suscept test differ antimicrobi perform isol c jejuni five c coli chicken isol c jejuni chicken three c coli chicken three c coli pork use disk diffus method c jejuni c coli isol high resist cefazolin sulfamethoxazoletrimethoprim among c jejuni isol chicken isol resist nalidix acid ciprofloxacin levofloxacin ampicillin minocyclin isol resist minocyclin nalidix acid ciprofloxacin levofloxacin ampicillin among c coli isol isol chicken chicken pork resist nalidix acid ciprofloxacin levofloxacin frequenc multi drug resist mdr c jejuni c coli strain chicken respect lower isol respect one c jejuni two c coli isol resist six antibiot howev two c jejuni one c coli isol chicken resist seven five antibiot respect c coli isol pork resist five antibiot high frequenc amr strain c coli isol pork suggest appropri use antimicrobi requir swine husbandri | D000890;D002167;D002169;D017000;D016123;D000080305;D000069466 | T007;T047;T121;T168 |
34,673,328 | enterobacteriacea coliform yeast mold contamin pattern peanut compar product storag use practic knowledg food safeti among grower seneg peanut peanut product signific revenu sourc smallhold farmer senegales peanut basin howev microbi contamin product storag great affect market access produc peanut product emerg possibl sourc foodborn ill encourag discuss intern standard peanut studi interview household throughout senegales peanut basin assess current product practic storag method produc prior knowledg microbi contamin use question survey member household oral complet survey train enumer result compar microbiolog result obtain peanut sampl collect time interview use linear regress analysi varianc model sampl collect store peanut household peanut shell total enterobacteriacea coliform yeast mold popul enumer sampl analyz greater upper detect limit enterobacteriacea coliform respect total sampl detect limit yeast mold popul produc awar pathogen bacteria aflatoxin respect signific differ observ microbi popul household took prevent measur microbi contamin addit four household report wash kitchen utensil use eat report alway wash hand eat enumer ask report peanut storag contain type contain store ground time collect interact storag contain type contain store ground signific enterobacteriacea coliform signific yeast mold addit storag contain type peanut store ground includ regress model method predict contamin level enterobacteriacea coliform knowledg first studi analyz relationship among enterobacteriacea coliform yeast mold contamin produc knowledg senegales peanut result provid preliminari data inform futur studi determin pathogen preval impact prevent measur minim microbi contamin peanut produc seneg | D010367;D004755 | T007;T002 |
34,673,327 | refin cype templat system deciph ligand interact templat system predict human cype mediat reaction drug metab rev refin introduct idea trigger residu residu initi movement ligand activ site refin system also includ idea bi molecul bind angl placement allow sit divers type ligand templat use idea common templat system human cypa cypa cypa drug metab pharmacokinet reaction distinct chemic publish cype ligand examin refin system verif good poor substrat regioselect also inhibitori interact avail faith ligand placement refin templat rule interact mode accompani deciph inform lead judgement refin cype templat system thus offer reliabl estim human cype catalysi toward ligand divers structur | D019388;D019392 | T116;T126 |
34,673,326 | evalu frequenc follow respons predict biomark respons cognit train schizophrenia neurophysiolog biomark auditori process show promis predict outcom follow auditori base target cognit train tct schizophrenia viabil frequenc follow respons ffr biomark yet examin despit ecolog face valid auditori base intervent ffr event relat potenti erp reflect earli auditori process predict schizophrenia patient would show acut longer term ffr malleabl context tct patient random either tct n treatment usual tau n electroencephalographi record rapid present auditori speech stimulus treatment one hour train h train wherea patient tct group show chang ffr train amplitud reduct observ tau ffr posit associ perform measur singl word nois percept tct group measur sentenc nois percept group psychometr reliabl analys ffr score indic high intern consist low one hour week test rest reliabl find support dissoci measur speech discrimin along hierarchi cortic subcort earli auditori inform process schizophrenia | D003072;D012559;D013067 | T048;T041 |
34,673,325 | long term impact covid infect sleep mental health cross section studi long term impact covid infect mental health peopl relat sever unclear aim studi long term effect post covid diseas sleep mental health detect possibl relationship sever covid onset sleep mental ill enrol particip month post covid infect group non sever sever critic accord accord guidanc particip assess use pittsburgh sleep qualiti index post traumat stress disord ptsd checklist dsm symptom checklist test psychiatr symptom psychiatr symptom follow poor sleep ptsd somat obsess compuls ocd depress anxieti phobic anxieti psychotic diabet oxygen support mechan ventil risk sleep impair high neutrophillymphocyt ratio nlr risk factor ptsd psychiatr ill sever risk factor femal diabet oxygen support mechan ventil abnorm sleep somat anxieti common mental ill post covid critic group common associ ptsd anxieti psychosi femal diabet oxygen support mechan ventil high nlr level vulner mental ill post covid | D000086382;D013313 | T048;T047;T067 |
34,673,324 | intramolecular charg transfer dynam excit state diphenylamin substitut oxadiazol deriv excit state dynam process two diphenylamin substitut symmetr oxadiazol deriv differ solvent studi femtosecond transient absorpt spectroscopi reveal cyclohexan local excit le state relax intramolecular charg transfer ict state within ps timescal decay ground state tetrahydrofuran acetonitril ict state stabil via solvat besid le ict convers within ps anoth ict solvent stabil ict ssict convers ps time scale could also observ eventu decay ground state wherea ict ssict process acetonitril slower tetrahydrofuran lead radiationless deactiv domin ict state deactiv process low fluoresc quantum effici result offer guidanc understand relationship low fluoresc quantum effici excit state deactiv mechan organ conjug molecul would help design new advanc opto electron materi | D004159 | T121;T109 |
34,673,320 | limoniastrum guyonianum behavior season condit fluctuat sabkha mader tunisia sabkha biotop sever environment factor ie salin drought temperatur etc especi dri season affect halophyt develop cope harm condit halophyt use multipl mechan adapt studi focus effect environment condit chang year sabkha mader medenin tunisia physiolog biochem behavior limoniastrum guyonianum use model approach studi show model depict well r month fluctuat studi paramet habitat dri period june septemb salin soil increas remark high level ec na content result high na content aerial part follow nutrient defici k ca mg result disrupt l guyonianum decreas water potenti negat valu maintain osmot potenti use inorgan osmolyt ie na organ osmolyt ie sugar sucros fructos glucos xylitol organ acid citric malic acid addit co assimil rate stomat conduct transpir rate photosynthet pigment decreas signific increas salin phenol compound content antioxid activ increas signific dri period result increas level h lipid peroxid increas high correl soil salin air temperatur mainten tissu hydrat ie moder decreas relat water content accumul sugar organ acid enhanc phenol compound amount increas antioxid activ dri period suggest l guyonianum possess effici toler mechan allow plant withstand season fluctuat climat condit natur biotop | D006861;D029606 | T130;T121;T002;T197 |
34,673,319 | role na transport hkt hkt tomato salt toler function loss cheesmania allel root aerial part analyz physiolog impact function loss cheesmania allel hkt hkt loci root aerial part tomato plant order determin relat contribut locus differ tissu plant na k homeostasi subsequ tomato salt toler generat differ reciproc rootstockscion combin non silenc singl rnai silenc line schkt schkt well silenc line loci near isogen line nil homozyg solanum cheesmania haplotyp contain hkt loci subject salin natur greenhous condit result show salt treatment reduc veget growth alter na k ratio leav flower negat affect fruit product particular graft combin contain singl silenc schkt doubl silenc schkt schkt line use scion conclud remov na xylem schkt aerial part plant even greater impact na homeostasi root level salin condit also schkt function loss rootstock great reduc na k ratio leaf flower tissu minim yield loss salin result suggest addit xylem na unload schkt could also involv na upload phloem thus promot na recircul aerial part root recircul na root phloem could favour schkt silenc root | D018551 | T002;T168 |
34,673,318 | elucid xenoestrogen metabol non target stabl isotop assist mass spectrometri breast cancer cell environment exposur xenoestrogen ie chemic imit hormon estradiol potenti influenc hormon homeostasi action detail knowledg xenobiot biotransform process cell model key transfer knowledg learn vitro model vivo relev studi elucid metabol two natur occur phyto mycoestrogen name genistein zearalenon estrogen receptor posit breast cancer cell line mcf aid stabl isotop assist metabolom bioinformat tool metextract ii metabol studi time cours experi h h h incub twelv six biotransform product zearalenon genistein detect respect clear demonstr abund xenobiot biotransform capabl cell zearalenon underw extens phase metabol result zearalenol zel molecul known possess signific higher estrogen sever phase ii metabolit sulfo glycoconjug nativ compound major phase metabolit zel moreov potenti adduct zearalenon vitamin sever hydroxyl metabolit annot genistein metabol result sulfat combin sulfat hydroxyl acetyl glucuronid unexpect adduct format pentos hexos sugar kinet metabolit format subsequ excret extracellular medium reveal time depend increas biotransform product untarget elucid biotransform product form cell cultur experi enabl improv meaning interpret toxicolog assay potenti identifi unexpect unknown metabolit | D001943;D015025 | T131;T191;T109 |
34,673,317 | perchlor chlorat breast milk infant formula babi supplementari food implic infant exposur perchlor chlorat ubiquit pollut various type foodstuff drink water environment compart rais great concern due potenti advers effect human thyroid function dietari intak consid predomin pathway human exposur perchlor chlorat nevertheless data human exposur chemic remain limit particular vulner popul infant present studi breast milk infant formula babi supplementari food tap water sampl collect south china level perchlor chlorat measur sampl perchlor chlorat frequent detect measur sampl differ type sampl median concentr perchlor gl gkg gkg gl respect median concentr chlorat gl gkg gkg non detect respect health risk assess use hazard quotient suggest perchlor chlorat exposur sampl babi food expect increas risk advers health effect knowledg first studi simultan investig perchlor chlorat exposur chines infant via food intak | D002704;D004785 | T131;T121;T197 |
34,673,316 | spread airborn antibiot resist anim farm environ dispers pattern exposur risk anim farm consid critic reservoir antibiot resist gene arg antibiot resist bacteria arb spread antibiot resist anim farm surround environ via aerosol becom grow concern investig dispers pattern exposur risk airborn arg especi zoonot pathogen environ chicken dairi farm aerosol dust anim fece sampl collect livestock hous surround environ upwind downwind area assess arg profil antibiot resist phenotyp genotyp airborn staphylococcus spp especi analyz reveal exposur risk airborn arg result show airborn arg detect upwind downwind air environ wherein least bacteri taxa dispers anim hous moreov atmospher dispers model show airborn arg dispers anim hous distanc km along wind direct clinic import pathogen identifi airborn cultur bacteria genus staphylococcus sphingomona acinetobact potenti bacteri host airborn arg airborn staphylococcus spp isol environ chicken farm n dairi farm n notabl isol chicken relat environ multidrug resist clinic relev antibiot carri methicillin resist gene meca associ arg mges presenc numer arg divers pathogen dust anim hous downwind residenti area indic accumul anim fece origin arg bioaerosol employe local resid chick farm environ expos chicken origin arg multidrug resist staphylococcus spp via inhal studi highlight potenti exposur risk airborn arg antibiot resist pathogen human health | D005798;D055624 | T007;T028 |
34,673,315 | suicid risk suicid bereav role loss relat characterist mental health hopeless suicid bereav associ increas risk sever negat mental health outcom suicid purpos studi examin associ mental health symptom suicid ideat among suicid bereav take multipl factor account | D001601;D008603 | T041 |
34,673,314 | longev studi determin appropri storag condit sexual lubric use spectroscop spectrometr techniqu increas number report case assail use condom sexual lubric sexual predat understand dna semin fluid one main form evid use connect suspect victim crime scene therefor use condom sexual assault case increas dilemma led research type trace evid eg sexual lubric studi present herein perform determin optim storag time length condit appropri store trace lubric residu research project use fourier transform infrar spectroscopi ftir direct analysi real time high resolut mass spectrometri dart hrms gas chromatographi mass spectrometri gc ms techniqu analyz store swab contain sexual lubric timepoint month blank person lubric condom swab store sever environment condit swab storag allow determin whether lubric degrad thus advers affect abil recogn classif pattern result spectra instrument use identifi environment degrad lubric sampl generat investig lead pearson correl coeffici time plot chemic compon use determin chemic breakdown occur lubric pattern chang signific result show strongest correl occur initi timepoint one month correl decreas consist eighteen month best storag condit determin c humid abil understand effect environ time analysi sexual lubric may offer help inform analyz sexual assault kit | D012742 | T048;T037 |
34,673,313 | metabol variat caribbean giant barrel spong influenc age sea depth biochem differenti wide distribut long live marin organ accord age depth water grow intrigu topic marin biolog especi sessil life form spong could expect activ regul biolog process interact environ chemic signal multidimension manner recent year develop chemic profil method metabolom provid approach encourag investig chemic interact organ studi lc ms base metabolom follow featur base molecular network fbmn use explor effect biotic environment factor metabolom giant barrel spong chosen model organ distribut throughout wide rang sea depth allow identif differ metabol composit spong relat age depth | D011161;D047131 | T204 |
34,673,312 | criterion valid interpret singl assess numer evalu sane self report recoveri patient neck pain sane prom recoveri may assist clinician clinic decis make discharg plan psychometr measur properti sane yet determin neck pain | D004185;D019547 | T184;T060 |
34,673,311 | preval risk factor acut stress disord femal victim sexual assault sexual assault one traumat event person experi despit inform regard risk factor associ develop acut stress disord asd sexual assault victim scarc follow prospect cohort studi design examin preval risk factor asd women expos recent sexual assault total women treat emerg depart univers general hospit short sexual assault sociodemograph clinic sexual assault relat variabl collect acut stress disord interview use estim preval asd three week post sa victim n met asd diagnosi use dsm criteria wherea n met asd diagnosi use dsm iv criteria risk factor associ develop asd nation psychiatr histori peritraumat dissoci type assault conclus preval asd femal victim recent sexual assault high affect approxim two third recognit risk factor associ asd develop like peritraumat dissoci type assault may aid prompt detect vulner women requir earli specif intervent short trauma | D019548;D012742;D013313;D040701 | T037;T068;T048;T098 |
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